TreeWAS – Variant ID: rs5746647

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K60.3 Anal fistula	0.029	0.971	0.000
K61.0 Anal abscess	0.025	0.975	0.000
K61 Abscess of anal and rectal regions	0.020	0.980	0.000
R12 Heartburn	0.000	0.981	0.019
K61.3 Ischiorectal abscess	0.019	0.981	0.000
K60 Fissure and fistula of anal and rectal regions	0.018	0.982	0.000
H36.0 Diabetic retinopathy	0.000	0.983	0.017
H33.3 Retinal breaks without detachment	0.000	0.983	0.017
K60.2 Anal fissure, unspecified	0.016	0.984	0.000
K61.4 Intrasphincteric abscess	0.015	0.984	0.000
K61.2 Anorectal abscess	0.015	0.985	0.000
K61.1 Rectal abscess	0.015	0.985	0.000
K60.5 Anorectal fistula	0.015	0.985	0.000
H36 Retinal disorders in diseases classified elsewhere	0.000	0.986	0.014
D12.4 Descending colon	0.014	0.986	0.000
K60.0 Acute anal fissure	0.013	0.987	0.000
H33 Retinal detachments and breaks	0.000	0.987	0.013
K60.4 Rectal fistula	0.013	0.987	0.000
H30-H36 Disorders of choroid and retina	0.000	0.988	0.012
K60.1 Chronic anal fissure	0.011	0.989	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.989	0.010
H33.5 Other retinal detachments	0.000	0.990	0.010
K62.8 Other specified diseases of anus and rectum	0.010	0.990	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.990	0.010
H31 Other disorders of choroid	0.000	0.990	0.010
H30 Chorioretinal inflammation	0.000	0.991	0.009
H33.4 Traction detachment of retina	0.000	0.991	0.009
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.991	0.009
D12.2 Ascending colon	0.009	0.991	0.000
H34 Retinal vascular occlusions	0.000	0.991	0.008
H35 Other retinal disorders	0.000	0.992	0.008
H31.1 Choroidal degeneration	0.000	0.992	0.008
C90.0 Multiple myeloma	0.008	0.992	0.000
C83.3 Large cell (diffuse)	0.008	0.992	0.000
H31.3 Choroidal haemorrhage and rupture	0.000	0.992	0.007
H33.2 Serous retinal detachment	0.000	0.992	0.008
H31.8 Other specified disorders of choroid	0.000	0.993	0.007
H31.4 Choroidal detachment	0.000	0.993	0.007
H31.2 Hereditary choroidal dystrophy	0.000	0.993	0.007
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.007	0.993	0.000
H31.9 Disorder of choroid, unspecified	0.000	0.993	0.007
H30.2 Posterior cyclitis	0.000	0.993	0.007
C90 Multiple myeloma and malignant plasma cell neoplasms	0.007	0.993	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.007	0.993	0.000
H35.8 Other specified retinal disorders	0.000	0.993	0.007
H31.0 Chorioretinal scars	0.000	0.993	0.007
H35.0 Background retinopathy and retinal vascular changes	0.000	0.993	0.007
H30.8 Other chorioretinal inflammations	0.000	0.993	0.007
H30.1 Disseminated chorioretinal inflammation	0.000	0.993	0.007
H30.0 Focal chorioretinal inflammation	0.000	0.993	0.007
H30.9 Chorioretinal inflammation, unspecified	0.000	0.993	0.007
H35.6 Retinal haemorrhage	0.000	0.993	0.007
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.000	0.993	0.007
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.000	0.993	0.007
H34.9 Retinal vascular occlusion, unspecified	0.000	0.993	0.007
C92 Myeloid leukaemia	0.007	0.993	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.007	0.993	0.000
H34.2 Other retinal artery occlusions	0.000	0.993	0.007
C91 Lymphoid leukaemia	0.007	0.993	0.000
D12.5 Sigmoid colon	0.007	0.993	0.000
H34.0 Transient retinal artery occlusion	0.000	0.994	0.006
H35.5 Hereditary retinal dystrophy	0.000	0.994	0.006
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.006	0.994	0.000
H35.2 Other proliferative retinopathy	0.000	0.994	0.006
H34.8 Other retinal vascular occlusions	0.000	0.994	0.006
H35.1 Retinopathy of prematurity	0.000	0.994	0.006
C95 Leukaemia of unspecified cell type	0.006	0.994	0.000
C91.1 Chronic lymphocytic leukaemia	0.006	0.994	0.000
C92.1 Chronic myeloid leukaemia	0.006	0.994	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.006	0.994	0.000
C92.0 Acute myeloid leukaemia	0.006	0.994	0.000
H35.7 Separation of retinal layers	0.000	0.994	0.006
C93 Monocytic leukaemia	0.006	0.994	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.006	0.994	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.005	0.994	0.000
C90.1 Plasma cell leukaemia	0.005	0.994	0.000
H34.1 Central retinal artery occlusion	0.000	0.994	0.005
H35.9 Retinal disorder, unspecified	0.000	0.994	0.005
C94 Other leukaemias of specified cell type	0.005	0.994	0.000
C86 Other specified types of T/NK-cell lymphoma	0.005	0.994	0.000
D12.9 Anus and anal canal	0.005	0.994	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.005	0.994	0.000
C83.2 Mixed small and large cell (diffuse)	0.005	0.995	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
C83.7 Burkitt's tumour	0.005	0.995	0.000
K55-K64 Other diseases of intestines	0.005	0.995	0.000
C90.3 Solitary plasmacytoma	0.005	0.995	0.000
C83.6 Undifferentiated (diffuse)	0.005	0.995	0.000
C83.4 Immunoblastic (diffuse)	0.005	0.995	0.000
C92.9 Myeloid leukaemia, unspecified	0.005	0.995	0.000
C83.5 Lymphoblastic (diffuse)	0.005	0.995	0.000
K62.0 Anal polyp	0.005	0.995	0.000
C91.0 Acute lymphoblastic leukaemia	0.005	0.995	0.000
C91.5 Adult T-cell leukaemia	0.005	0.995	0.000
C88 Malignant immunoproliferative diseases	0.005	0.995	0.000
C92.7 Other myeloid leukaemia	0.005	0.995	0.000
C83.1 Small cleaved cell (diffuse)	0.005	0.995	0.000
C92.4 Acute promyelocytic leukaemia	0.005	0.995	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.005	0.995	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.005	0.995	0.000
C92.3 Myeloid sarcoma	0.005	0.995	0.000
K62 Other diseases of anus and rectum	0.005	0.995	0.000
Y84.8 Other medical procedures	0.000	0.995	0.005
C95.9 Leukaemia, unspecified	0.005	0.995	0.000
C92.2 Subacute myeloid leukaemia	0.005	0.995	0.000
C85.1 B-cell lymphoma, unspecified	0.005	0.995	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.005	0.995	0.000
C91.7 Other lymphoid leukaemia	0.005	0.995	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.005	0.995	0.000
C91.3 Prolymphocytic leukaemia	0.005	0.995	0.000
C91.2 Subacute lymphocytic leukaemia	0.005	0.995	0.000
C85.0 Lymphosarcoma	0.005	0.995	0.000
C92.5 Acute myelomonocytic leukaemia	0.005	0.995	0.000
C83.0 Small cell (diffuse)	0.005	0.995	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.005	0.995	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.995	0.005
C95.1 Chronic leukaemia of unspecified cell type	0.005	0.995	0.000
C91.4 Hairy-cell leukaemia	0.005	0.995	0.000
C90.2 Plasmacytoma, extramedullary	0.004	0.995	0.000
A41.9 Septicaemia, unspecified	0.005	0.995	0.000
C95.0 Acute leukaemia of unspecified cell type	0.004	0.995	0.000
C95.7 Other leukaemia of unspecified cell type	0.004	0.995	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.004	0.995	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.004	0.995	0.000
C91.9 Lymphoid leukaemia, unspecified	0.004	0.995	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.004	0.995	0.000
C93.1 Chronic monocytic leukaemia	0.004	0.995	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.004	0.995	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.004	0.995	0.000
D12.7 Rectosigmoid junction	0.004	0.995	0.000
C84.5 Other and unspecified T-cell lymphomas	0.004	0.995	0.000
K62.2 Anal prolapse	0.004	0.996	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.004	0.996	0.000
C82.4 Follicular lymphoma grade IIIb	0.004	0.996	0.000
C82.3 Follicular lymphoma grade IIIa	0.004	0.996	0.000
C94.4 Acute panmyelosis	0.004	0.996	0.000
D12.1 Appendix	0.004	0.996	0.000
H54.7 Unspecified visual loss	0.000	0.996	0.004
C82.2 Large cell, follicular	0.004	0.996	0.000
C93.9 Monocytic leukaemia, unspecified	0.004	0.996	0.000
C93.7 Other monocytic leukaemia	0.004	0.996	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.004	0.996	0.000
C93.2 Subacute monocytic leukaemia	0.004	0.996	0.000
C93.0 Acute monocytic leukaemia	0.004	0.996	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.004	0.996	0.000
C71.9 Brain, unspecified	0.000	0.996	0.004
C84.9 Mature T/NK-cell lymphoma, unspecified	0.004	0.996	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.004	0.996	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.004	0.996	0.000
C84.3 Lymphoepithelioid lymphoma	0.004	0.996	0.000
C84.2 T-zone lymphoma	0.004	0.996	0.000
C84.1 Sezary's diease	0.004	0.996	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.004	0.996	0.000
C86.4 Blastic NK-cell lymphoma	0.004	0.996	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.004	0.996	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.004	0.996	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.004	0.996	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.004	0.996	0.000
C94.7 Other specified leukaemias	0.004	0.996	0.000
C94.5 Acute myelofibrosis	0.004	0.996	0.000
C94.3 Mast cell leukaemia	0.004	0.996	0.000
C94.2 Acute megakaryoblastic leukaemia	0.004	0.996	0.000
C94.1 Chronic erythraemia	0.004	0.996	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.004	0.996	0.000
H33.0 Retinal detachment with retinal break	0.000	0.996	0.004
C82.6 Cutaneous follicle centre lymphoma	0.004	0.996	0.000
C82.5 Diffuse follicle centre lymphoma	0.004	0.996	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.004	0.996	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.004	0.996	0.000
C96.8 Histiocytic sarcoma	0.004	0.996	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.004	0.996	0.000
C96.3 True histiocytic lymphoma	0.004	0.996	0.000
C96.2 Malignant mast cell tumour	0.004	0.996	0.000
C96.1 Malignant histiocytosis	0.004	0.996	0.000
C96.0 Letterer-Siwe disease	0.004	0.996	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.004	0.996	0.000
C84.0 Mycosis fungoides	0.004	0.996	0.000
K62.6 Ulcer of anus and rectum	0.004	0.996	0.000
H54 Blindness and low vision	0.000	0.996	0.004
C84.4 Peripheral T-cell lymphoma	0.004	0.996	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.004	0.996	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.004	0.996	0.000
C88.7 Other malignant immunoproliferative diseases	0.004	0.996	0.000
C88.3 Immunoproliferative small intestinal disease	0.004	0.996	0.000
C88.2 Gamma heavy chain disease	0.004	0.996	0.000
C88.1 Alpha heavy chain disease	0.004	0.996	0.000
T43.2 Other and unspecified antidepressants	0.000	0.996	0.004
D12.3 Transverse colon	0.004	0.996	0.000
C82.0 Small cleaved cell, follicular	0.004	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.996	0.004
K55 Vascular disorders of intestine	0.004	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.996	0.004
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.996	0.004
A41 Other septicaemia	0.004	0.996	0.000
H35.4 Peripheral retinal degeneration	0.000	0.996	0.003
H54.5 Low vision, one eye	0.000	0.996	0.004
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
A41.8 Other specified septicaemia	0.004	0.996	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.996	0.004
T43.6 Psychostimulants with abuse potential	0.000	0.996	0.004
C88.0 Waldenstrom's macroglobulinaemia	0.003	0.996	0.000
Y84.0 Cardiac catheterisation	0.000	0.996	0.004
H54.2 Low vision, both eyes	0.000	0.996	0.004
C81 Hodgkin's disease	0.003	0.996	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.996	0.003
K55.9 Vascular disorder of intestine, unspecified	0.003	0.996	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.996	0.003
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
H54.6 Unqualified visual loss, one eye	0.000	0.997	0.003
T43.9 Psychotropic drug, unspecified	0.000	0.997	0.003
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
H54.4 Blindness, one eye	0.000	0.997	0.003
H54.3 Unqualified visual loss, both eyes	0.000	0.997	0.003
K62.4 Stenosis of anus and rectum	0.003	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.997	0.003
K64.9 Haemorrhoids, unspecified	0.003	0.997	0.000
K64.8 Other specified haemorrhoids	0.003	0.997	0.000
K64.5 Perianal venous thrombosis	0.003	0.997	0.000
K64.4 Residual haemorrhoidal skin tags	0.003	0.997	0.000
K64.3 Fourth degree haemorrhoids	0.003	0.997	0.000
K64.2 Third degree haemorrhoids	0.003	0.997	0.000
K64.1 Second degree haemorrhoids	0.003	0.997	0.000
K64.0 First degree haemorrhoids	0.003	0.997	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.003	0.997	0.000
H47.1 Papilloedema, unspecified	0.000	0.997	0.003
H54.1 Blindness, one eye, low vision, other eye	0.000	0.997	0.003
K55.0 Acute vascular disorders of intestine	0.003	0.997	0.000
H47.5 Disorders of other visual pathways	0.000	0.997	0.003
H47.2 Optic atrophy	0.000	0.997	0.003
H47.3 Other disorders of optic disk	0.000	0.997	0.003
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.997	0.003
A41.4 Septicaemia due to anaerobes	0.003	0.997	0.000
D12.8 Rectum	0.003	0.997	0.000
K62.7 Radiation proctitis	0.003	0.997	0.000
N92.3 Ovulation bleeding	0.000	0.997	0.003
A41.3 Septicaemia due to Haemophilus influenzae	0.003	0.997	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.997	0.003
A41.1 Septicaemia due to other specified staphylococcus	0.003	0.997	0.000
H53-H54 Visual disturbances and blindness	0.000	0.997	0.003
K62.9 Disease of anus and rectum, unspecified	0.003	0.997	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.997	0.003
H47.7 Disorder of visual pathways, unspecified	0.000	0.997	0.003
H47.6 Disorders of visual cortex	0.000	0.997	0.003
H47.4 Disorders of optic chiasm	0.000	0.997	0.003
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.003	0.997	0.000
C81.7 Other Hodgkin's disease	0.002	0.997	0.000
L60.0 Ingrowing nail	0.000	0.997	0.003
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.002	0.997	0.000
C81.3 Lymphocytic depletion	0.002	0.997	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.003	0.997	0.000
J33.0 Polyp of nasal cavity	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
Y84.1 Kidney dialysis	0.000	0.997	0.003
H54.0 Blindness, both eyes	0.000	0.997	0.003
K55.8 Other vascular disorders of intestine	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.000	0.997	0.003
K55.2 Angiodysplasia of colon	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
A49.0 Staphylococcal infection, unspecified	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.003
Chapter VII Diseases of the eye and adnexa	0.000	0.997	0.003
C81.1 Nodular sclerosis	0.002	0.997	0.000
D06.9 Cervix, unspecified	0.003	0.997	0.000
Z91.5 Personal history of self-harm	0.000	0.997	0.003
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.997	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
C81.0 Lymphocytic predominance	0.002	0.997	0.000
I63.9 Cerebral infarction, unspecified	0.003	0.997	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.002	0.997	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.000	0.997	0.002
K55.1 Chronic vascular disorders of intestine	0.002	0.997	0.000
H46 Optic neuritis	0.000	0.997	0.002
C81.2 Mixed cellularity	0.002	0.997	0.001
Y84.5 Insertion of gastric or duodenal sound	0.000	0.997	0.002
C71.3 Parietal lobe	0.000	0.997	0.002
Y84.9 Medical procedure, unspecified	0.000	0.997	0.002
Y84.7 Blood-sampling	0.000	0.997	0.002
C81.9 Hodgkin's disease, unspecified	0.002	0.998	0.000
Y84.3 Shock therapy	0.000	0.998	0.002
Y84.4 Aspiration of fluid	0.000	0.998	0.002
H55-H59 Other disorders of eye and adnexa	0.000	0.998	0.002
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.000	0.998	0.002
H59.0 Vitreous syndrome following cataract surgery	0.000	0.998	0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
C71.1 Frontal lobe	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
C71.2 Temporal lobe	0.000	0.998	0.002
T50.8 Diagnostic agents	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.002
T50.5 Appetite depressants	0.000	0.998	0.002
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.002
A49 Bacterial infection of unspecified site	0.002	0.998	0.000
C71.4 Occipital lobe	0.000	0.998	0.002
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
C71.7 Brain stem	0.000	0.998	0.002
K22.7 Barrett's oesophagus	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.000	0.998	0.002
H48.0 Optic atrophy in diseases classified elsewhere	0.000	0.998	0.002
N87.0 Mild cervical dysplasia	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.998	0.002
K62.3 Rectal prolapse	0.002	0.998	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.000	0.998	0.002
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
A49.1 Streptococcal infection, unspecified	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.000	0.998	0.002
D12.6 Colon, unspecified	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.998	0.002
T39.0 Salicylates	0.000	0.998	0.002
A30-A49 Other bacterial diseases	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
A49.2 Haemophilus influenzae infection, unspecified	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
J31.0 Chronic rhinitis	0.000	0.998	0.002
K22.1 Ulcer of oesophagus	0.002	0.998	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
T47.4 Other laxatives	0.000	0.998	0.002
H53.9 Visual disturbance, unspecified	0.000	0.998	0.002
H52 Disorders of refraction and accommodation	0.000	0.998	0.002
H49 Paralytic strabismus	0.000	0.998	0.002
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
T47.7 Emetics	0.000	0.998	0.002
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.002
T47.5 Digestants	0.000	0.998	0.002
T47.3 Saline and osmotic laxatives	0.000	0.998	0.002
A49.3 Mycoplasma infection, unspecified	0.002	0.998	0.000
H02.4 Ptosis of eyelid	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.998	0.002
T47.2 Stimulant laxatives	0.000	0.998	0.002
H52.3 Anisometropia and aniseikonia	0.000	0.998	0.002
T42.3 Barbiturates	0.000	0.998	0.002
T42.0 Hydantoin derivatives	0.000	0.998	0.002
H52.7 Disorder of refraction, unspecified	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
A48 Other bacterial diseases, not elsewhere classified	0.002	0.998	0.000
A48.1 Legionnaires' disease	0.002	0.998	0.000
D12.0 Caecum	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
T48.4 Expectorants	0.000	0.998	0.002
T48.3 Antitussives	0.000	0.998	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
T48.0 Oxytocic drugs	0.000	0.998	0.002
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.998	0.002
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
J47 Bronchiectasis	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
H10-H13 Disorders of conjunctiva	0.000	0.998	0.002
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.000	0.998	0.002
H02.1 Ectropion of eyelid	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
H53 Visual disturbances	0.000	0.998	0.002
F60.3 Emotionally unstable personality disorder	0.000	0.998	0.002
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
T48.5 Anti-common-cold drugs	0.000	0.998	0.001
H49.8 Other paralytic strabismus	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.000	0.998	0.002
H53.0 Amblyopia ex anopsia	0.000	0.998	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H57 Other disorders of eye and adnexa	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T45.4 Iron and its compounds	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.001
A44 Bartonellosis	0.002	0.998	0.000
A43 Nocardiosis	0.002	0.998	0.000
A37 Whooping cough	0.002	0.998	0.000
A36 Diphtheria	0.002	0.998	0.000
A32 Listeriosis	0.002	0.998	0.000
A31 Infection due to other mycobacteria	0.002	0.998	0.000
A30 Leprosy [Hansen's disease]	0.002	0.998	0.000
A38 Scarlet fever	0.002	0.998	0.000
A35 Other tetanus	0.002	0.998	0.000
A34 Obstetrical tetanus	0.002	0.998	0.000
A33 Tetanus neonatorum	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
N86 Erosion and ectropion of cervix uteri	0.000	0.998	0.002
H52.2 Astigmatism	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.001
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.001
T36.6 Rifamycins	0.000	0.998	0.001
T36.5 Aminoglycosides	0.000	0.998	0.001
T36.4 Tetracyclines	0.000	0.998	0.001
T36.2 Chloramphenicol group	0.000	0.998	0.001
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.001
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.002
T42.1 Iminostilbenes	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.001
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.001
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.001
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.001
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.001
A42 Actinomycosis	0.002	0.998	0.000
H51 Other disorders of binocular movement	0.000	0.998	0.002
A49.9 Bacterial infection, unspecified	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.001
A40 Streptococcal septicaemia	0.002	0.998	0.000
D07.1 Vulva	0.000	0.998	0.002
H49.4 Progressive external ophthalmoplegia	0.000	0.998	0.002
T45.5 Anticoagulants	0.000	0.998	0.001
T46.1 Calcium-channel blockers	0.000	0.998	0.001
Y84.6 Urinary catheterisation	0.000	0.998	0.001
K91.3 Postoperative intestinal obstruction	0.000	0.998	0.002
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.000	0.998	0.001
T42.4 Benzodiazepines	0.000	0.998	0.002
Y84.2 Radiological procedure and radiotherapy	0.000	0.998	0.001
A39 Meningococcal infection	0.001	0.998	0.000
A40.9 Streptococcal septicaemia, unspecified	0.001	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.000	0.998	0.001
H52.6 Other disorders of refraction	0.000	0.998	0.002
H52.5 Disorders of accommodation	0.000	0.998	0.002
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.000	0.998	0.001
H58.1 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.001
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.000	0.998	0.001
T36.3 Macrolides	0.000	0.998	0.001
T36.0 Penicillins	0.000	0.998	0.001
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.001
Z98.8 Other specified postsurgical states	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations