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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs5749446
log Bayes Factor = <0.0001
Chromosome 22   position 32,880,585  (GRCh37) Explore rs5749446 on Ensembl!
Variant rs5749446 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Y86 Sequelae of other accidents
0.000 0.956 0.044
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.017 0.983 0.000
D13.1 Stomach
0.014 0.986 0.000
S27 Injury of other and unspecified intrathoracic organs
0.000 0.986 0.014
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.000 0.986 0.014
S27.0 Traumatic pneumothorax
0.000 0.987 0.013
S27.3 Other injuries of lung
0.000 0.987 0.013
S22.10 Multiple fractures of thoracic spine (closed)
0.000 0.987 0.013
S27.30 Other injuries of lung (without open wound into thoracic cavity)
0.000 0.987 0.013
S22.1 Multiple fractures of thoracic spine
0.000 0.988 0.012
S22 Fracture of rib(s), sternum and thoracic spine
0.000 0.988 0.012
S27.2 Traumatic heamopneumothorax
0.000 0.988 0.012
S27.8 Injury of other specified intrathoracic organs
0.000 0.989 0.011
S20-S29 Injuries to the thorax
0.000 0.989 0.011
D13.4 Liver
0.011 0.989 0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)
0.000 0.989 0.011
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.011 0.989 0.000
S21 Open wound of thorax
0.000 0.990 0.010
S22.0 Fracture of thoracic vertebra
0.000 0.990 0.010
S27.9 Injury of unspecified intrathoracic organ
0.000 0.990 0.010
S27.7 Multiple injuries of intrathoracic organs
0.000 0.990 0.010
S27.6 Injury of pleura
0.000 0.990 0.010
S27.5 Injury of thoracic trachea
0.000 0.990 0.010
S27.4 Injury of bronchus
0.000 0.990 0.010
S22.2 Fracture of sternum
0.000 0.990 0.010
D13.2 Duodenum
0.010 0.990 0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)
0.000 0.990 0.010
O47.9 False labour, unspecified
0.010 0.990 0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)
0.000 0.990 0.009
R44.0 Auditory hallucinations
0.000 0.990 0.009
S22.00 Fracture of thoracic vertebra (closed)
0.000 0.991 0.009
S24 Injury of nerves and spinal cord at thorax level
0.000 0.991 0.009
S22.11 Multiple fractures of thoracic spine (open)
0.000 0.991 0.009
S22.4 Multiple fractures of ribs
0.000 0.991 0.009
S21.1 Open wound of front wall of thorax
0.000 0.991 0.009
O70.0 First degree perineal laceration during delivery
0.009 0.991 0.000
S22.9 Fracture of bony thorax, part unspecified
0.000 0.991 0.009
S22.8 Fracture of other parts of bony thorax
0.000 0.991 0.009
S22.20 Fracture of sternum (closed)
0.000 0.991 0.009
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)
0.000 0.991 0.009
S21.9 Open wound of thorax, part unspecified
0.000 0.991 0.009
S21.2 Open wound of back wall of thorax
0.000 0.991 0.009
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)
0.000 0.991 0.008
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)
0.000 0.991 0.008
D13.7 Endocrine pancreas
0.008 0.992 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.000 0.992 0.008
S26 Injury of heart
0.000 0.992 0.008
S25 Injury of blood vessels of thorax
0.000 0.992 0.008
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.000 0.992 0.008
D13.6 Pancreas
0.008 0.992 0.000
S22.5 Flail chest
0.000 0.992 0.008
L30.8 Other specified dermatitis
0.008 0.992 0.000
L30.9 Dermatitis, unspecified
0.008 0.992 0.000
S27.1 Traumatic haemothorax
0.000 0.992 0.008
S22.01 Fracture of thoracic vertebra (open)
0.000 0.992 0.008
S21.8 Open wound of other parts of thorax
0.000 0.992 0.008
S21.7 Multiple open wounds of thoracic wall
0.000 0.992 0.008
L30 Other dermatitis
0.008 0.992 0.000
S24.1 Other and unspecified injuries of thoracic spinal cord
0.000 0.992 0.007
S27.41 Injury of bronchus (with open wound into thoracic cavity)
0.000 0.992 0.007
S27.40 Injury of bronchus (without open wound into thoracic cavity)
0.000 0.992 0.007
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)
0.000 0.992 0.007
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)
0.000 0.992 0.007
S27.61 Injury of pleura (with open wound into thoracic cavity)
0.000 0.992 0.007
S27.60 Injury of pleura (without open wound into thoracic cavity)
0.000 0.992 0.007
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)
0.000 0.992 0.007
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)
0.000 0.992 0.007
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)
0.000 0.992 0.007
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)
0.000 0.992 0.007
S22.21 Fracture of sternum (open)
0.000 0.993 0.007
D13.9 Ill-defined sites within the digestive system
0.007 0.993 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.007 0.993 0.000
S29 Other and unspecified injuries of thorax
0.000 0.993 0.007
S22.3 Fracture of rib
0.000 0.993 0.007
S21.0 Open wound of breast
0.000 0.993 0.007
S24.6 Injury of unspecified nerve of thorax
0.000 0.993 0.007
S24.5 Injury of other nerves of thorax
0.000 0.993 0.007
S24.4 Injury of thoracic sympathetic nerves
0.000 0.993 0.007
S24.3 Injury of peripheral nerves of thorax
0.000 0.993 0.007
S24.2 Injury of nerve root of thoracic spine
0.000 0.993 0.007
S24.0 Concussion and oedema of thoracic spinal cord
0.000 0.993 0.007
S22.40 Multiple fractures of ribs (closed)
0.000 0.993 0.007
B37.3 Candidiasis of vulva and vagina
0.007 0.993 0.000
S22.41 Multiple fractures of ribs (open)
0.000 0.993 0.007
L30.1 Dyshidrosis [pompholyx]
0.007 0.993 0.000
Z86.7 Personal history of diseases of the circulatory system
0.007 0.993 0.000
S22.81 Fracture of other parts of bony thorax (open)
0.000 0.993 0.006
S22.80 Fracture of other parts of bony thorax (closed)
0.000 0.993 0.006
S22.91 Fracture of bony thorax, part unspecified (open)
0.000 0.993 0.006
S22.90 Fracture of bony thorax, part unspecified (closed)
0.000 0.993 0.006
L30.3 Infective dermatitis
0.006 0.993 0.000
D13.3 Other and unspecified parts of small intestine
0.006 0.993 0.000
D13.0 Oesophagus
0.006 0.993 0.000
Z74.0 Reduced mobility
0.006 0.994 0.000
S25.9 Injury of unspecified blood vessel of thorax
0.000 0.994 0.006
S25.8 Injury of other blood vessels of thorax
0.000 0.994 0.006
S25.7 Injury of multiple blood vessels of thorax
0.000 0.994 0.006
S25.5 Injury of intercostal blood vessels
0.000 0.994 0.006
S25.4 Injury of pulmonary blood vessels
0.000 0.994 0.006
S25.3 Injury of innominate or subclavian vein
0.000 0.994 0.006
S25.2 Injury of superior vena cava
0.000 0.994 0.006
S25.1 Injury of innominate or subclavian artery
0.000 0.994 0.006
S25.0 Injury of thoracic aorta
0.000 0.994 0.006
S26.9 Injury of heart, unspecified
0.000 0.994 0.006
S26.8 Other injuries of heart
0.000 0.994 0.006
S26.0 Injury of heart with haemopericardium
0.000 0.994 0.006
S28.1 Traumatic amputation of part of thorax
0.000 0.994 0.006
S28.0 Crushed chest
0.000 0.994 0.006
S23.5 Sprain and strain of other and unspecified parts of thorax
0.000 0.994 0.006
S23.3 Sprain and strain of thoracic spine
0.000 0.994 0.006
S23.2 Dislocation of other and unspecified parts of thorax
0.000 0.994 0.006
S23.1 Dislocation of thoracic vertebra
0.000 0.994 0.006
S23.0 Traumatic rupture of thoracic intervertebral disk
0.000 0.994 0.006
S22.51 Flail chest (open)
0.000 0.994 0.006
S23.4 Sprain and strain of ribs and sternum
0.000 0.994 0.006
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.000 0.994 0.006
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)
0.000 0.994 0.006
R44 Other symptoms and signs involving general sensations and perceptions
0.000 0.994 0.006
T92.2 Sequelae of fracture at wrist and hand level
0.000 0.994 0.006
L30.5 Pityriasis alba
0.006 0.994 0.000
L30.4 Erythema intertrigo
0.006 0.994 0.000
L30.2 Cutaneous autosensitisation
0.006 0.994 0.000
L30.0 Nummular dermatitis
0.006 0.994 0.000
S22.50 Flail chest (closed)
0.000 0.995 0.005
T92 Sequelae of injuries of upper limb
0.000 0.995 0.005
H15.1 Episcleritis
0.005 0.995 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.000 0.995 0.005
S29.7 Multiple injuries of thorax
0.000 0.995 0.005
S22.31 Fracture of rib (open)
0.000 0.995 0.005
S29.8 Other specified injuries of thorax
0.000 0.995 0.005
K31.7 Polyp of stomach and duodenum
0.005 0.995 0.000
R44.2 Other hallucinations
0.000 0.995 0.005
I44.2 Atrioventricular block, complete
0.000 0.995 0.005
H40.2 Primary angle-closure glaucoma
0.005 0.995 0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
0.005 0.995 0.000
S29.0 Injury of muscle and tendon at thorax level
0.000 0.995 0.005
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.000 0.995 0.005
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.000 0.995 0.005
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)
0.000 0.995 0.004
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)
0.000 0.995 0.004
S26.81 Other injuries of heart (with open wound into thoracic cavity)
0.000 0.995 0.004
S26.80 Other injuries of heart (without open wound into thoracic cavity)
0.000 0.995 0.004
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)
0.000 0.995 0.004
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)
0.000 0.995 0.004
T92.9 Sequelae of unspecified injury of upper limb
0.000 0.995 0.005
S79.9 Unspecified injury of hip and thigh
0.000 0.995 0.005
Y89 Sequelae of other external causes
0.000 0.995 0.005
D13.5 Extrahepatic bile ducts
0.004 0.995 0.000
R44.3 Hallucinations, unspecified
0.000 0.995 0.005
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.005 0.995 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.000 0.995 0.004
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.000 0.995 0.004
R44.1 Visual hallucinations
0.000 0.995 0.004
S29.9 Unspecified injury of thorax
0.000 0.996 0.004
T92.0 Sequelae of open wound of upper limb
0.000 0.996 0.004
S20 Superficial injury of thorax
0.000 0.996 0.004
J38.7 Other diseases of larynx
0.004 0.996 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.000 0.996 0.004
T92.4 Sequelae of injury of nerve of upper limb
0.000 0.996 0.004
S00.9 Superficial injury of head, part unspecified
0.000 0.996 0.004
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.000 0.996 0.004
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)
0.000 0.996 0.003
H65.3 Chronic mucoid otitis media
0.004 0.996 0.000
Y89.9 Sequelae of unspecified external cause
0.000 0.996 0.004
H65 Nonsuppurative otitis media
0.004 0.996 0.000
Y89.1 Sequelae of war operations
0.000 0.996 0.003
Y89.0 Sequelae of legal intervention
0.000 0.996 0.003
H65.4 Other chronic nonsuppurative otitis media
0.004 0.996 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.000 0.996 0.004
S20.0 Contusion of breast
0.000 0.996 0.003
S82.21 Fracture of shaft of tibia (open)
0.000 0.996 0.004
H15 Disorders of sclera
0.004 0.996 0.000
S90 Superficial injury of ankle and foot
0.000 0.996 0.004
S90.8 Other superficial injuries of ankle and foot
0.000 0.996 0.004
E73.9 Lactose intolerance, unspecified
0.004 0.996 0.000
Y88 Sequelae of surgical and medical care as external cause
0.000 0.997 0.003
H74 Other disorders of middle ear and mastoid
0.003 0.997 0.000
H74.4 Polyp of middle ear
0.003 0.997 0.000
S20.4 Other superficial injuries of back wall of thorax
0.000 0.997 0.003
H65.2 Chronic serous otitis media
0.003 0.997 0.000
H66.3 Other chronic suppurative otitis media
0.003 0.997 0.000
S20.7 Multiple superficial injuries of thorax
0.000 0.997 0.003
H66 Suppurative and unspecified otitis media
0.003 0.997 0.000
S22.30 Fracture of rib (closed)
0.000 0.997 0.003
H40.9 Glaucoma, unspecified
0.003 0.997 0.000
H66.4 Suppurative otitis media, unspecified
0.003 0.997 0.000
H15.0 Scleritis
0.003 0.997 0.000
I35.0 Aortic (valve) stenosis
0.003 0.997 0.000
R49.0 Dysphonia
0.003 0.997 0.000
G35 Multiple sclerosis
0.000 0.997 0.003
H74.9 Disorder of middle ear and mastoid, unspecified
0.003 0.997 0.000
H74.0 Tympanosclerosis
0.003 0.997 0.000
I49.9 Cardiac arrhythmia, unspecified
0.003 0.997 0.000
Y87.2 Sequelae of events of undetermined intent
0.000 0.997 0.003
H74.3 Other acquired abnormalities of ear ossicles
0.003 0.997 0.000
F99 Mental disorder, not otherwise specified
0.000 0.997 0.003
S90.1 Contusion of toe(s) without damage to nail
0.000 0.997 0.003
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.000 0.997 0.003
H40 Glaucoma
0.003 0.997 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.003 0.997 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.000 0.997 0.003
S90.3 Contusion of other and unspecified parts of foot
0.000 0.997 0.003
H65.0 Acute serous otitis media
0.003 0.997 0.000
H66.0 Acute suppurative otitis media
0.003 0.997 0.000
M79.2 Neuralgia and neuritis, unspecified
0.000 0.997 0.003
Y87.0 Sequelae of intentional self-harm
0.000 0.997 0.003
S92.30 Fracture of metatarsal bone (closed)
0.000 0.997 0.003
H40.0 Glaucoma suspect
0.003 0.997 0.000
S20.1 Other and unspecified superficial injuries of breast
0.000 0.997 0.003
H65-H75 Diseases of middle ear and mastoid
0.003 0.997 0.000
H15.9 Disorder of sclera, unspecified
0.003 0.997 0.000
S90.7 Multiple superficial injuries of ankle and foot
0.000 0.997 0.003
S90.2 Contusion of toe(s) with damage to nail
0.000 0.997 0.003
S90.0 Contusion of ankle
0.000 0.997 0.003
H65.1 Other acute nonsuppurative otitis media
0.003 0.997 0.000
S82.60 Fracture of lateral malleolus (closed)
0.000 0.997 0.003
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use
0.000 0.997 0.003
N36.2 Urethral caruncle
0.000 0.997 0.003
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use
0.000 0.997 0.003
H15.8 Other disorders of sclera
0.003 0.997 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.000 0.997 0.003
D39.1 Ovary
0.003 0.997 0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures
0.000 0.997 0.002
S92.3 Fracture of metatarsal bone
0.000 0.997 0.003
H40.4 Glaucoma secondary to eye inflammation
0.003 0.997 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.003 0.997 0.000
S20.3 Other superficial injuries of front wall of thorax
0.000 0.997 0.002
T38.1 Thyroid hormones and substitutes
0.003 0.997 0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)
0.000 0.997 0.002
H20.0 Acute and subacute iridocyclitis
0.000 0.997 0.002
H60.3 Other infective otitis externa
0.003 0.997 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.997 0.003
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.000 0.997 0.002
H74.2 Discontinuity and dislocation of ear ossicles
0.002 0.997 0.000
Y87.1 Sequelae of assault
0.000 0.997 0.002
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.000 0.997 0.002
S92.00 Fracture of calcaneus (closed)
0.000 0.997 0.002
T81.3 Disruption of operation wound, not elsewhere classified
0.003 0.997 0.000
H70 Mastoiditis and related conditions
0.002 0.997 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.002 0.998 0.000
T40.2 Other opioids
0.002 0.998 0.000
S79 Other and unspecified injuries of hip and thigh
0.000 0.998 0.002
H40.6 Glaucoma secondary to drugs
0.002 0.998 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.000 0.998 0.002
H60 Otitis externa
0.002 0.998 0.000
S92 Fracture of foot, except ankle
0.000 0.998 0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.002 0.998 0.000
O47 False labour
0.002 0.998 0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)
0.000 0.998 0.002
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.002 0.998 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.002 0.998 0.000
H60.4 Cholesteatoma of external ear
0.002 0.998 0.000
H33.2 Serous retinal detachment
0.000 0.998 0.002
S92.7 Multiple fractures of foot
0.000 0.998 0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.002 0.998 0.000
T92.1 Sequelae of fracture of arm
0.000 0.998 0.002
M79.24 Neuralgia and neuritis, unspecified (Hand)
0.000 0.998 0.002
M79.23 Neuralgia and neuritis, unspecified (Forearm)
0.000 0.998 0.002
M79.22 Neuralgia and neuritis, unspecified (Upper arm)
0.000 0.998 0.002
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)
0.000 0.998 0.002
S92.70 Multiple fractures of foot (closed)
0.000 0.998 0.002
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.002 0.998 0.000
H60.5 Acute otitis externa, non-infective
0.002 0.998 0.000
S92.0 Fracture of calcaneus
0.000 0.998 0.002
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.000 0.998 0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.002 0.998 0.000
H68 Eustachian salpingitis and obstruction
0.002 0.998 0.000
H67 Otitis media in diseases classified elsewhere
0.002 0.998 0.000
H70.1 Chronic mastoiditis
0.002 0.998 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.002 0.998 0.000
Z43.2 Attention to ileostomy
0.002 0.998 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.002 0.998 0.000
H60.8 Other otitis externa
0.002 0.998 0.000
Y45.0 Opioids and related analgesics
0.000 0.998 0.002
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.002 0.998 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.002 0.998 0.000
S92.2 Fracture of other tarsal bone(s)
0.000 0.998 0.002
H72 Perforation of tympanic membrane
0.002 0.998 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.002 0.998 0.000
H60.9 Otitis externa, unspecified
0.002 0.998 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.002 0.998 0.000
Y85 Sequelae of transport accidents
0.000 0.998 0.002
D11.0 Parotid gland
0.002 0.998 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.002 0.998 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.998 0.002
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.002 0.998 0.000
H74.1 Adhesive middle ear disease
0.002 0.998 0.000
L94.2 Calcinosis cutis
0.002 0.998 0.000
S79.8 Other specified injuries of hip and thigh
0.000 0.998 0.002
S92.40 Fracture of great toe (closed)
0.000 0.998 0.002
S92.31 Fracture of metatarsal bone (open)
0.000 0.998 0.002
H72.8 Other perforations of tympanic membrane
0.002 0.998 0.000
S92.4 Fracture of great toe
0.000 0.998 0.002
T40.6 Other and unspecified narcotics
0.002 0.998 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.002 0.998 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.002 0.998 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.000 0.998 0.002
S92.20 Fracture of other tarsal bone(s) (closed)
0.000 0.998 0.002
C82.2 Large cell, follicular
0.002 0.998 0.000
Z74 Problems related to care-provider dependency
0.002 0.998 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.002 0.998 0.000
H73 Other disorders of tympanic membrane
0.002 0.998 0.000
H40.5 Glaucoma secondary to other eye disorders
0.002 0.998 0.000
T45.0 Antiallergic and antiemetic drugs
0.002 0.998 0.000
D48.6 Breast
0.000 0.998 0.002
H40.3 Glaucoma secondary to eye trauma
0.002 0.998 0.000
H70.9 Mastoiditis, unspecified
0.002 0.998 0.000
H70.2 Petrositis
0.002 0.998 0.000
H70.0 Acute mastoiditis
0.002 0.998 0.000
S79.7 Multiple injuries of hip and thigh
0.000 0.998 0.002
H60.2 Malignant otitis externa
0.002 0.998 0.000
T38.9 Other and unspecified hormone antagonists
0.002 0.998 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.002 0.998 0.000
T38.7 Androgens and anabolic congeners
0.002 0.998 0.000
T38.5 Other oestrogens and progestogens
0.002 0.998 0.000
T38.4 Oral contraceptives
0.002 0.998 0.000
T38.2 Antithyroid drugs
0.002 0.998 0.000
T38.0 Glucocorticoids and synthetic analogues
0.002 0.998 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.002 0.998 0.000
S82.2 Fracture of shaft of tibia
0.000 0.998 0.002
S92.71 Multiple fractures of foot (open)
0.000 0.998 0.002
S92.5 Fracture of other toe
0.000 0.998 0.002
T40.5 Cocaine
0.002 0.998 0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.002 0.998 0.000
D11.9 Major salivary gland, unspecified
0.002 0.998 0.000
H67.8 Otitis media in other diseases classified elsewhere
0.002 0.998 0.000
H67.1 Otitis media in viral diseases classified elsewhere
0.002 0.998 0.000
H67.0 Otitis media in bacterial diseases classified elsewhere
0.002 0.998 0.000
H68.1 Obstruction of Eustachian tube
0.002 0.998 0.000
H68.0 Eustachian salpingitis
0.002 0.998 0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.002 0.998 0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.002 0.998 0.000
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere
0.002 0.998 0.000
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere
0.002 0.998 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.000 0.998 0.002
H70.8 Other mastoiditis and related conditions
0.002 0.998 0.000
Z74.9 Problem related to care-provider dependency, unspecified
0.002 0.998 0.000
S92.21 Fracture of other tarsal bone(s) (open)
0.000 0.998 0.002
H72.0 Central perforation of tympanic membrane
0.002 0.998 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.002 0.998 0.000
T40.8 Lysergide [LSD]
0.002 0.998 0.000
T40.7 Cannabis (derivatives)
0.002 0.998 0.000
T40.3 Methadone
0.002 0.998 0.000
T40.1 Heroin
0.002 0.998 0.000
T40.0 Opium
0.002 0.998 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.000 0.998 0.002
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.002 0.998 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.002 0.998 0.000
H20.1 Chronic iridocyclitis
0.002 0.998 0.000
R49.8 Other and unspecified voice disturbances
0.002 0.998 0.000
R49 Voice disturbances
0.002 0.998 0.000
H60.1 Cellulitis of external ear
0.002 0.998 0.000
H60.0 Abscess of external ear
0.002 0.998 0.000
S82.6 Fracture of lateral malleolus
0.000 0.998 0.002
S92.9 Fracture of foot, unspecified
0.000 0.998 0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.002 0.998 0.000
S82.40 Fracture of fibula alone (closed)
0.000 0.998 0.002
F33.1 Recurrent depressive disorder, current episode moderate
0.002 0.998 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.000 0.998 0.002
O47.0 False labour before 37 completed weeks of gestation
0.002 0.998 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.000 0.998 0.002
C82.4 Follicular lymphoma grade IIIb
0.002 0.998 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.002 0.998 0.000
R77.9 Abnormality of plasma protein, unspecified
0.002 0.998 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.000 0.998 0.002
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.000 0.998 0.002
S92.01 Fracture of calcaneus (open)
0.000 0.998 0.002
H40.8 Other glaucoma
0.002 0.998 0.000
N95.3 States associated with artificial menopause
0.000 0.998 0.002
Q54.0 Hypospadias, balanic
0.000 0.998 0.002
H20.9 Iridocyclitis, unspecified
0.002 0.998 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.000 0.998 0.002
Z74.3 Need for continuous supervision
0.002 0.998 0.000
C82.6 Cutaneous follicle centre lymphoma
0.002 0.998 0.000
C82.5 Diffuse follicle centre lymphoma
0.002 0.998 0.000
C82.3 Follicular lymphoma grade IIIa
0.002 0.998 0.000
H73.0 Acute myringitis
0.002 0.998 0.000
T40.4 Other synthetic narcotics
0.002 0.998 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.002 0.998 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.002 0.998 0.000
C82.0 Small cleaved cell, follicular
0.002 0.998 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.002 0.998 0.000
S92.51 Fracture of other toe (open)
0.000 0.998 0.002
S20.2 Contusion of thorax
0.001 0.998 0.001
T93.8 Sequelae of other specified injuries of lower limb
0.000 0.998 0.002
H20 Iridocyclitis
0.002 0.998 0.000
T45.4 Iron and its compounds
0.002 0.998 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.002 0.998 0.000
S92.1 Fracture of talus
0.000 0.998 0.001
H72.1 Attic perforation of tympanic membrane
0.002 0.998 0.000
T50.1 Loop [high-ceiling] diuretics
0.002 0.998 0.000
T36 Poisoning by systemic antibiotics
0.002 0.998 0.000
H73.1 Chronic myringitis
0.001 0.998 0.000
S90-S99 Injuries to the ankle and foot
0.000 0.998 0.002
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.002 0.998 0.000
T36.0 Penicillins
0.002 0.998 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.002 0.998 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.002 0.998 0.000
L05.9 Pilonidal cyst without abscess
0.000 0.998 0.002
R49.2 Hypernasality and hyponasality
0.001 0.998 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.002 0.998 0.000
S92.91 Fracture of foot, unspecified (open)
0.000 0.998 0.001
S93.0 Dislocation of ankle joint
0.000 0.998 0.002
T50.8 Diagnostic agents
0.001 0.998 0.000
T50.7 Analeptics and opioid receptor antagonists
0.001 0.998 0.000
T50.5 Appetite depressants
0.001 0.998 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.001 0.998 0.000
T50.0 Mineralocorticoids and their antagonists
0.001 0.998 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.000 0.998 0.002
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.002 0.998 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.000 0.998 0.001
Z74.8 Other problems related to care-provider dependency
0.001 0.998 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.002 0.998 0.000
Q12.0 Congenital cataract
0.000 0.998 0.002
Z74.2 Need for assistance at home and no other household member able to render care
0.001 0.998 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.000 0.998 0.002
G11.9 Hereditary ataxia, unspecified
0.002 0.998 0.000
L81.4 Other melanin hyperpigmentation
0.002 0.998 0.000
S82.4 Fracture of fibula alone
0.000 0.998 0.002
T50.6 Antidotes and chelating agents, not elsewhere classified
0.001 0.998 0.000
E73 Lactose intolerance
0.002 0.998 0.000
T93 Sequelae of injuries of lower limb
0.000 0.998 0.002
S92.50 Fracture of other toe (closed)
0.000 0.998 0.001
R73.0 Abnormal glucose tolerance test
0.002 0.998 0.000
T93.2 Sequelae of other fractures of lower limb
0.000 0.998 0.002
M00.91 Pyogenic arthritis, unspecified (Shoulder region)
0.000 0.998 0.001
S41.1 Open wound of upper arm
0.000 0.998 0.002
T45.9 Primarily systemic and haematological agent, unspecified
0.001 0.998 0.000
T45.8 Other primarily systemic and haematological agents
0.001 0.998 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.001 0.998 0.000
T45.6 Fibrinolysis-affecting drugs
0.001 0.998 0.000
T45.3 Enzymes, not elsewhere classified
0.001 0.998 0.000
Z74.1 Need for assistance with personal care
0.001 0.998 0.000
M62.66 Muscle strain (Lower leg)
0.001 0.998 0.000
S92.41 Fracture of great toe (open)
0.000 0.998 0.001
H20.2 Lens-induced iridocyclitis
0.001 0.998 0.000
H72.2 Other marginal perforations of tympanic membrane
0.001 0.998 0.000
T36.4 Tetracyclines
0.001 0.998 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.001 0.998 0.000
M54.37 Sciatica (Lumbosacral region)
0.001 0.998 0.000
S92.11 Fracture of talus (open)
0.000 0.998 0.001
B02.9 Zoster without complication
0.000 0.998 0.002
D86.0 Sarcoidosis of lung
0.002 0.998 0.000
R49.1 Aphonia
0.001 0.998 0.000
T50.4 Drugs affecting uric acid metabolism
0.001 0.998 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.001 0.998 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.001 0.998 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.000 0.998 0.001
D48.0 Bone and articular cartilage
0.000 0.998 0.001
T36.9 Systemic antibiotic, unspecified
0.001 0.998 0.000
T36.8 Other systemic antibiotics
0.001 0.998 0.000
T36.7 Antifungal antibiotics, systemically used
0.001 0.998 0.000
T36.6 Rifamycins
0.001 0.998 0.000
T36.5 Aminoglycosides
0.001 0.998 0.000
T36.3 Macrolides
0.001 0.998 0.000
T36.2 Chloramphenicol group
0.001 0.998 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.001 0.998 0.000
M54.36 Sciatica (Lumbar region)
0.001 0.999 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.001 0.999 0.000
Z75.4 Unavailability and inaccessibility of other helping agencies
0.001 0.999 0.000
H69 Other disorders of Eustachian tube
0.001 0.999 0.000
S98 Traumatic amputation of ankle and foot
0.000 0.999 0.001
S95 Injury of blood vessels at ankle and foot level
0.000 0.999 0.001
S94 Injury of nerves at ankle and foot level
0.000 0.999 0.001
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.001 0.999 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.000 0.999 0.001
M79.80 Other specified soft tissue disorders (Multiple sites)
0.000 0.999 0.001
S82.11 Fracture of upper end of tibia (open)
0.000 0.999 0.001
S82.61 Fracture of lateral malleolus (open)
0.000 0.999 0.001
S92.90 Fracture of foot, unspecified (closed)
0.000 0.999 0.001
B00.5 Herpesviral ocular disease
0.001 0.999 0.000
H21.0 Hyphaema
0.001 0.999 0.000
Q54.1 Hypospadias, penile
0.000 0.999 0.001
H21 Other disorders of iris and ciliary body
0.001 0.999 0.000
S93.3 Dislocation of other and unspecified parts of foot
0.000 0.999 0.001
S93.2 Rupture of ligaments at ankle and foot level
0.000 0.999 0.001
T45.2 Vitamins, not elsewhere classified
0.001 0.999 0.000
H34.2 Other retinal artery occlusions
0.001 0.999 0.000
H66.9 Otitis media, unspecified
0.001 0.999 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.999 0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.000 0.999 0.001
S93.4 Sprain and strain of ankle
0.000 0.999 0.001
S93.5 Sprain and strain of toe(s)
0.000 0.999 0.001
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.000 0.999 0.001
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.000 0.999 0.001
M62.68 Muscle strain (Other)
0.001 0.999 0.000
S82.41 Fracture of fibula alone (open)
0.000 0.999 0.001
C45.0 Mesothelioma of pleura
0.000 0.999 0.001
D33.2 Brain, unspecified
0.001 0.999 0.000
E73.8 Other lactose intolerance
0.001 0.999 0.000
E73.1 Secondary lactase deficiency
0.001 0.999 0.000
E73.0 Congenital lactase deficiency
0.001 0.999 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.001 0.999 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.001 0.999 0.000
I77.0 Arteriovenous fistula, acquired
0.001 0.999 0.000
L81.8 Other specified disorders of pigmentation
0.001 0.999 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.000 0.999 0.001
T93.4 Sequelae of injury of nerve of lower limb
0.000 0.999 0.001
D11 Benign neoplasm of major salivary glands
0.001 0.999 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.000 0.999 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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