TreeWAS – Variant ID: rs57994353

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M81.99 Osteoporosis, unspecified (Site unspecified)	0.066	0.934	0.000
M81.9 Osteoporosis, unspecified	0.059	0.941	0.000
M81.98 Osteoporosis, unspecified (Other)	0.053	0.947	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.050	0.950	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.047	0.953	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.045	0.955	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.044	0.956	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.042	0.957	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.042	0.957	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.042	0.957	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.037	0.963	0.000
L57.0 Actinic keratosis	0.033	0.967	0.000
M81 Osteoporosis without pathological fracture	0.031	0.969	0.000
H65-H75 Diseases of middle ear and mastoid	0.028	0.972	0.000
H71 Cholesteatoma of middle ear	0.028	0.972	0.000
H73 Other disorders of tympanic membrane	0.025	0.975	0.000
H70 Mastoiditis and related conditions	0.025	0.975	0.000
H65 Nonsuppurative otitis media	0.024	0.976	0.000
H69 Other disorders of Eustachian tube	0.024	0.976	0.000
M81.2 Osteoporosis of disuse	0.023	0.977	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.023	0.977	0.000
H81.0 Meniere's disease	0.023	0.977	0.000
H69.9 Eustachian tube disorder, unspecified	0.023	0.977	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.023	0.977	0.000
M81.4 Drug-induced osteoporosis	0.023	0.977	0.000
M81.8 Other osteoporosis	0.022	0.978	0.000
M81.6 Localised osteoporosis [Lequesne]	0.022	0.978	0.000
M81.5 Idiopathic osteoporosis	0.022	0.978	0.000
M81.1 Postoophorectomy osteoporosis	0.022	0.978	0.000
H74 Other disorders of middle ear and mastoid	0.022	0.978	0.000
H74.4 Polyp of middle ear	0.022	0.978	0.000
M31.6 Other giant cell arteritis	0.022	0.978	0.000
M81.0 Postmenopausal osteoporosis	0.021	0.979	0.000
M31 Other necrotising vasculopathies	0.021	0.979	0.000
H65.2 Chronic serous otitis media	0.021	0.979	0.000
H70.1 Chronic mastoiditis	0.021	0.979	0.000
H70.9 Mastoiditis, unspecified	0.021	0.979	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.020	0.979	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.020	0.980	0.000
H68 Eustachian salpingitis and obstruction	0.020	0.980	0.000
H67 Otitis media in diseases classified elsewhere	0.020	0.980	0.000
M31.3 Wegener's granulomatosis	0.020	0.980	0.000
H73.1 Chronic myringitis	0.020	0.980	0.000
H66 Suppurative and unspecified otitis media	0.020	0.980	0.000
H81 Disorders of vestibular function	0.020	0.980	0.000
M31.9 Necrotising vasculopathy, unspecified	0.019	0.981	0.000
Chapter VIII Diseases of the ear and mastoid process	0.019	0.981	0.000
H73.8 Other specified disorders of tympanic membrane	0.019	0.981	0.000
H80-H83 Diseases of inner ear	0.019	0.981	0.000
H73.0 Acute myringitis	0.018	0.981	0.000
H70.2 Petrositis	0.018	0.982	0.000
H70.0 Acute mastoiditis	0.018	0.982	0.000
H65.0 Acute serous otitis media	0.018	0.982	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.018	0.982	0.000
M31.0 Hypersensitivity angiitis	0.018	0.982	0.000
H69.0 Patulous Eustachian tube	0.017	0.982	0.000
H70.8 Other mastoiditis and related conditions	0.017	0.982	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.017	0.982	0.000
H65.1 Other acute nonsuppurative otitis media	0.017	0.983	0.000
H81.9 Disorder of vestibular function, unspecified	0.017	0.983	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.017	0.983	0.000
M81.28 Osteoporosis of disuse (Other)	0.017	0.983	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.017	0.983	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.017	0.983	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.017	0.983	0.000
M81.24 Osteoporosis of disuse (Hand)	0.017	0.983	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.017	0.983	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.017	0.983	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.017	0.983	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.017	0.983	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.017	0.983	0.000
M31.8 Other specified necrotising vasculopathies	0.017	0.983	0.000
M81.48 Drug-induced osteoporosis (Other)	0.016	0.983	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.016	0.983	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.016	0.983	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.016	0.983	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.016	0.983	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.016	0.983	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.016	0.983	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.016	0.983	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.016	0.983	0.000
H74.1 Adhesive middle ear disease	0.016	0.984	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.016	0.984	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.016	0.984	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.016	0.984	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.016	0.984	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.016	0.984	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.016	0.984	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.016	0.984	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.016	0.984	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.016	0.984	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.016	0.984	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.016	0.984	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.016	0.984	0.000
M81.58 Idiopathic osteoporosis (Other)	0.016	0.984	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.016	0.984	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.016	0.984	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.016	0.984	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.016	0.984	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.016	0.984	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.016	0.984	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.016	0.984	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.016	0.984	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.016	0.984	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.016	0.984	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.016	0.984	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.016	0.984	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.016	0.984	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.016	0.984	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.016	0.984	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.016	0.984	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.016	0.984	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.016	0.984	0.000
M81.89 Other osteoporosis (Site unspecified)	0.016	0.984	0.000
M81.88 Other osteoporosis (Other)	0.016	0.984	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.016	0.984	0.000
M81.86 Other osteoporosis (Lower leg)	0.016	0.984	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.016	0.984	0.000
M81.84 Other osteoporosis (Hand)	0.016	0.984	0.000
M81.83 Other osteoporosis (Forearm)	0.016	0.984	0.000
M81.82 Other osteoporosis (Upper arm)	0.016	0.984	0.000
M81.81 Other osteoporosis (Shoulder region)	0.016	0.984	0.000
M81.80 Other osteoporosis (Multiple sites)	0.016	0.984	0.000
H66.9 Otitis media, unspecified	0.016	0.984	0.000
M31.1 Thrombotic microangiopathy	0.016	0.984	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.016	0.984	0.000
H81.8 Other disorders of vestibular function	0.016	0.984	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.015	0.984	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.015	0.984	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.015	0.984	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.015	0.984	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.015	0.984	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.015	0.984	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.015	0.984	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.015	0.984	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.015	0.984	0.000
M31.2 Lethal midline granuloma	0.015	0.984	0.000
M31.7 Microscopic polyangiitis	0.015	0.984	0.000
H60-H62 Diseases of external ear	0.016	0.984	0.000
H60 Otitis externa	0.015	0.985	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.015	0.985	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.015	0.985	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.015	0.985	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.015	0.985	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.015	0.985	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.015	0.985	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.015	0.985	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.015	0.985	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.015	0.985	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.015	0.985	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.015	0.985	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.015	0.985	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.015	0.985	0.000
H68.1 Obstruction of Eustachian tube	0.015	0.985	0.000
H68.0 Eustachian salpingitis	0.015	0.985	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.015	0.985	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.015	0.985	0.000
H83 Other diseases of inner ear	0.015	0.985	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.014	0.985	0.000
H81.4 Vertigo of central origin	0.014	0.986	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.014	0.986	0.000
H66.0 Acute suppurative otitis media	0.014	0.986	0.000
H60.9 Otitis externa, unspecified	0.014	0.986	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.014	0.986	0.000
H60.0 Abscess of external ear	0.013	0.986	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.987	0.013
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.013	0.987	0.000
H65.3 Chronic mucoid otitis media	0.013	0.987	0.000
H66.3 Other chronic suppurative otitis media	0.013	0.987	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.013	0.987	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.013	0.987	0.000
H60.8 Other otitis externa	0.013	0.987	0.000
M80-M85 Disorders of bone density and structure	0.013	0.987	0.000
H72 Perforation of tympanic membrane	0.013	0.987	0.000
H81.3 Other peripheral vertigo	0.012	0.987	0.000
H60.5 Acute otitis externa, non-infective	0.012	0.988	0.000
H69.8 Other specified disorders of Eustachian tube	0.012	0.988	0.000
H60.3 Other infective otitis externa	0.012	0.988	0.000
M84 Disorders of continuity of bone	0.012	0.988	0.000
H74.0 Tympanosclerosis	0.012	0.988	0.000
H83.9 Disease of inner ear, unspecified	0.011	0.988	0.000
H83.0 Labyrinthitis	0.012	0.988	0.000
H83.3 Noise effects on inner ear	0.011	0.989	0.000
H60.2 Malignant otitis externa	0.011	0.989	0.000
L57.5 Actinic granuloma	0.011	0.989	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.011	0.989	0.000
H81.2 Vestibular neuronitis	0.011	0.989	0.000
Z97.8 Presence of other specified devices	0.000	0.989	0.011
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.011	0.989	0.000
M84.8 Other disorders of continuity of bone	0.011	0.989	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.011	0.989	0.000
H66.4 Suppurative otitis media, unspecified	0.011	0.989	0.000
H83.2 Labyrinthine dysfunction	0.011	0.989	0.000
H83.1 Labyrinthine fistula	0.011	0.989	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.989	0.011
L57.3 Poikiloderma of Civatte	0.010	0.989	0.000
L57.2 Cutis rhomboidalis nuchae	0.010	0.989	0.000
L57.1 Actinic reticuloid	0.010	0.989	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.010	0.989	0.000
M83 Adult osteomalacia	0.010	0.990	0.000
H83.8 Other specified diseases of inner ear	0.010	0.990	0.000
Z97 Presence of other devices	0.000	0.990	0.010
H72.9 Perforation of tympanic membrane, unspecified	0.010	0.990	0.000
M84.0 Malunion of fracture	0.010	0.990	0.000
M84.03 Malunion of fracture (Forearm)	0.010	0.990	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.010	0.990	0.000
H65.4 Other chronic nonsuppurative otitis media	0.009	0.990	0.000
L57.4 Cutis laxa senilis	0.009	0.990	0.000
M84.3 Stress fracture, not elsewhere classified	0.009	0.990	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.009	0.991	0.000
H80 Otosclerosis	0.009	0.991	0.000
H72.1 Attic perforation of tympanic membrane	0.009	0.991	0.000
M82 Osteoporosis in diseases classified elsewhere	0.009	0.991	0.000
M84.9 Disorder of continuity of bone, unspecified	0.009	0.991	0.000
M84.2 Delayed union of fracture	0.009	0.991	0.000
M84.02 Malunion of fracture (Upper arm)	0.009	0.991	0.000
H81.1 Benign paroxysmal vertigo	0.009	0.991	0.000
M83.9 Adult osteomalacia, unspecified	0.008	0.991	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.000	0.991	0.009
M84.83 Other disorders of continuity of bone (Forearm)	0.008	0.992	0.000
Z97.0 Presence of artificial eye	0.000	0.992	0.008
H62.8 Other disorders of external ear in diseases classified elsewhere	0.008	0.992	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.008	0.992	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
H62.2 Otitis externa in mycoses	0.008	0.992	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.008	0.992	0.000
N81.1 Cystocele	0.000	0.992	0.008
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.008	0.992	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.008	0.992	0.000
M84.88 Other disorders of continuity of bone (Other)	0.008	0.992	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.008	0.992	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.008	0.992	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.008	0.992	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.008	0.992	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.008	0.992	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.008	0.992	0.000
H72.8 Other perforations of tympanic membrane	0.008	0.992	0.000
H60.1 Cellulitis of external ear	0.008	0.992	0.000
M84.4 Pathological fracture, not elsewhere classified	0.008	0.992	0.000
H72.2 Other marginal perforations of tympanic membrane	0.008	0.992	0.000
H60.4 Cholesteatoma of external ear	0.007	0.992	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.992	0.008
M83.5 Other drug-induced osteomalacia in adults	0.007	0.992	0.000
M83.4 Aluminum bone disease	0.007	0.992	0.000
M83.3 Adult osteomalacia due to malnutrition	0.007	0.992	0.000
M83.2 Adult osteomalacia due to malabsorption	0.007	0.992	0.000
M83.1 Senile osteomalacia	0.007	0.992	0.000
M83.0 Puerperal osteomalacia	0.007	0.992	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.007	0.992	0.000
M83.8 Other adult osteomalacia	0.007	0.992	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.000	0.992	0.007
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.007	0.993	0.000
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.007	0.993	0.000
M84.09 Malunion of fracture (Site unspecified)	0.007	0.993	0.000
M84.08 Malunion of fracture (Other)	0.007	0.993	0.000
M84.00 Malunion of fracture (Multiple sites)	0.007	0.993	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.007	0.993	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.007	0.993	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.007	0.993	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.007	0.993	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.007	0.993	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.007	0.993	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.007	0.993	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.007	0.993	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.007	0.993	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.007	0.993	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.007	0.993	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.007	0.993	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.007	0.993	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.007	0.993	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.007	0.993	0.000
M84.04 Malunion of fracture (Hand)	0.007	0.993	0.000
Z97.4 Presence of external hearing-aid	0.000	0.993	0.007
H80.8 Other otosclerosis	0.006	0.993	0.000
H80.2 Cochlear otosclerosis	0.006	0.993	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.006	0.993	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.006	0.993	0.000
H40.1 Primary open-angle glaucoma	0.007	0.993	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.007	0.993	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.007	0.993	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.007	0.993	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.007	0.993	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.006	0.993	0.000
M84.28 Delayed union of fracture (Other)	0.006	0.993	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.006	0.993	0.000
M84.26 Delayed union of fracture (Lower leg)	0.006	0.993	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.006	0.993	0.000
M84.24 Delayed union of fracture (Hand)	0.006	0.993	0.000
M84.23 Delayed union of fracture (Forearm)	0.006	0.993	0.000
M84.22 Delayed union of fracture (Upper arm)	0.006	0.993	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.006	0.993	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.006	0.993	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.006	0.993	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.006	0.993	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.006	0.993	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.006	0.993	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.006	0.993	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.006	0.993	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.006	0.993	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.006	0.993	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.006	0.993	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.006	0.993	0.000
M80 Osteoporosis with pathological fracture	0.007	0.993	0.000
Z97.3 Presence of spectacles and contact lenses	0.000	0.993	0.006
G25.8 Other specified extrapyramidal and movement disorders	0.006	0.994	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.006	0.994	0.000
M83.98 Adult osteomalacia, unspecified (Other)	0.006	0.994	0.000
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.006	0.994	0.000
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.006	0.994	0.000
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M83.94 Adult osteomalacia, unspecified (Hand)	0.006	0.994	0.000
M83.93 Adult osteomalacia, unspecified (Forearm)	0.006	0.994	0.000
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.006	0.994	0.000
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.006	0.994	0.000
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.006	0.994	0.000
L85.9 Epidermal thickening, unspecified	0.006	0.994	0.000
M82.1 Osteoporosis in endocrine disorders	0.006	0.994	0.000
H90-H95 Other disorders of ear	0.006	0.994	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.006	0.994	0.000
H72.0 Central perforation of tympanic membrane	0.006	0.994	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.006	0.994	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.006	0.994	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.006	0.994	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.006	0.994	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.006	0.994	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.006	0.994	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.006	0.994	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.006	0.994	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.006	0.994	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.006	0.994	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.005	0.994	0.000
M83.08 Puerperal osteomalacia (Other)	0.005	0.994	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.005	0.994	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.005	0.994	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.005	0.994	0.000
M83.04 Puerperal osteomalacia (Hand)	0.005	0.994	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.005	0.994	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.005	0.994	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.005	0.994	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.005	0.994	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.005	0.994	0.000
M83.18 Senile osteomalacia (Other)	0.005	0.994	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.005	0.994	0.000
M83.16 Senile osteomalacia (Lower leg)	0.005	0.994	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.005	0.994	0.000
M83.14 Senile osteomalacia (Hand)	0.005	0.994	0.000
M83.13 Senile osteomalacia (Forearm)	0.005	0.994	0.000
M83.12 Senile osteomalacia (Upper arm)	0.005	0.994	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.005	0.994	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.005	0.994	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.005	0.994	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.005	0.994	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.005	0.994	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.005	0.994	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.005	0.994	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.005	0.994	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.005	0.994	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.005	0.994	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.005	0.994	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.005	0.994	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.005	0.994	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.005	0.994	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.005	0.994	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.005	0.994	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.005	0.994	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.005	0.994	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.005	0.994	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.005	0.994	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.005	0.994	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.005	0.994	0.000
M83.49 Aluminium bone disease (Site unspecified)	0.005	0.994	0.000
M83.48 Aluminium bone disease (Other)	0.005	0.994	0.000
M83.47 Aluminium bone disease (Ankle and foot)	0.005	0.994	0.000
M83.46 Aluminium bone disease (Lower leg)	0.005	0.994	0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.005	0.994	0.000
M83.44 Aluminium bone disease (Hand)	0.005	0.994	0.000
M83.43 Aluminium bone disease (Forearm)	0.005	0.994	0.000
M83.42 Aluminium bone disease (Upper arm)	0.005	0.994	0.000
M83.41 Aluminium bone disease (Shoulder region)	0.005	0.994	0.000
M83.40 Aluminium bone disease (Multiple sites)	0.005	0.994	0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.005	0.994	0.000
M83.58 Other drug-induced osteomalacia in adults (Other)	0.005	0.994	0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.005	0.994	0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.005	0.994	0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.005	0.994	0.000
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.005	0.994	0.000
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.005	0.994	0.000
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.005	0.994	0.000
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.005	0.994	0.000
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.005	0.994	0.000
M84.06 Malunion of fracture (Lower leg)	0.005	0.994	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.005	0.994	0.000
M83.88 Other adult osteomalacia (Other)	0.005	0.994	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.005	0.994	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.005	0.994	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.005	0.994	0.000
M83.84 Other adult osteomalacia (Hand)	0.005	0.994	0.000
M83.83 Other adult osteomalacia (Forearm)	0.005	0.994	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.005	0.994	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.005	0.994	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.005	0.994	0.000
L58 Radiodermatitis	0.005	0.994	0.000
L55 Sunburn	0.005	0.994	0.000
M84.01 Malunion of fracture (Shoulder region)	0.005	0.995	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.005	0.995	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.005	0.995	0.000
G25 Other extrapyramidal and movement disorders	0.005	0.995	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.005	0.995	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.005	0.995	0.000
M85 Other disorders of bone density and structure	0.005	0.995	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.005	0.995	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.005	0.995	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.005	0.995	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.005	0.995	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.005	0.995	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.005	0.995	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.005	0.995	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.005	0.995	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.005	0.995	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.005	0.995	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.005	0.995	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.005	0.995	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.005	0.995	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.005	0.995	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.005	0.995	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.005	0.995	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.005	0.995	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.005	0.995	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.005	0.995	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.005	0.995	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.005	0.995	0.000
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.005	0.995	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.005	0.995	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.005	0.995	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.005	0.995	0.000
G25.2 Other specified forms of tremor	0.005	0.995	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.005	0.995	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.005	0.995	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.005	0.995	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.005	0.995	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.005	0.995	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.005	0.995	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.005	0.995	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.005	0.995	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.005	0.995	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.005	0.995	0.000
G25.0 Essential tremor	0.005	0.995	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.005	0.995	0.000
L56.4 Polymorphous light eruption	0.005	0.995	0.000
M80.8 Other osteoporosis with pathological fracture	0.004	0.995	0.000
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified	0.004	0.995	0.000
L59.0 Erythema ab igne [dermatitis ab igne]	0.004	0.995	0.000
H61 Other disorders of external ear	0.005	0.995	0.000
H35.8 Other specified retinal disorders	0.000	0.995	0.005
M80.5 Idiopathic osteoporosis with pathological fracture	0.004	0.995	0.000
L56.3 Solar urticaria	0.004	0.995	0.000
L56.2 Photocontact dermatitis [berloque dermatitis]	0.004	0.995	0.000
L56.1 Drug photoallergic response	0.004	0.995	0.000
L56.0 Drug phototoxic response	0.004	0.995	0.000
H92 Otalgia and effusion of ear	0.004	0.995	0.000
H93 Other disorders of ear, not elsewhere classified	0.004	0.996	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.004	0.996	0.000
G24.5 Blepharospasm	0.004	0.996	0.000
M85.4 Solitary bone cyst	0.004	0.996	0.000
H40.2 Primary angle-closure glaucoma	0.004	0.996	0.000
L55.9 Sunburn, unspecified	0.004	0.996	0.000
L55.8 Other sunburn	0.004	0.996	0.000
L55.2 Sunburn of third degree	0.004	0.996	0.000
L55.1 Sunburn of second degree	0.004	0.996	0.000
L55.0 Sunburn of first degree	0.004	0.996	0.000
L58.9 Radiodermatitis, unspecified	0.004	0.996	0.000
L58.1 Chronic radiodermatitis	0.004	0.996	0.000
L58.0 Acute radiodermatitis	0.004	0.996	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.004	0.996	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.004	0.996	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.004	0.996	0.000
I31.9 Disease of pericardium, unspecified	0.004	0.996	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.004	0.996	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.004	0.996	0.000
M85.9 Disorder of bone density and structure, unspecified	0.004	0.996	0.000
C71.9 Brain, unspecified	0.004	0.996	0.000
G25.5 Other chorea	0.004	0.996	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.004	0.996	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.004	0.996	0.000
G25.4 Drug-induced chorea	0.004	0.996	0.000
K55.9 Vascular disorder of intestine, unspecified	0.004	0.996	0.000
G25.1 Drug-induced tremor	0.004	0.996	0.000
M85.5 Aneurysmal bone cyst	0.004	0.996	0.000
M85.3 Osteitis condensans	0.004	0.996	0.000
M85.1 Skeletal fluorosis	0.004	0.996	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.004	0.996	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.004	0.996	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.004	0.996	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.004	0.996	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.004	0.996	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.004	0.996	0.000
J45.0 Predominantly allergic asthma	0.004	0.996	0.000
H93.2 Other abnormal auditory perceptions	0.004	0.996	0.000
H61.8 Other specified disorders of external ear	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations