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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs580962
log Bayes Factor = 85.1195
Chromosome 6   position 32,925,692  (GRCh37) Explore rs580962 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
E10.4 With neurological complications
0.000 0.005 0.995
L40.9 Psoriasis, unspecified
0.995 0.005 0.000
L40 Psoriasis
0.993 0.007 0.000
L40.5 Arthropathic psoriasis
0.992 0.008 0.000
E40-E46 Malnutrition
0.000 0.028 0.972
E10.2 With renal complications
0.000 0.041 0.959
E46 Unspecified protein-energy malnutrition
0.000 0.048 0.952
L40.8 Other psoriasis
0.937 0.063 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.098 0.902
E10.5 With peripheral circulatory complications
0.000 0.147 0.853
K90 Intestinal malabsorption
0.000 0.150 0.850
E13 Other specified diabetes mellitus
0.000 0.163 0.837
E10.8 With unspecified complications
0.000 0.165 0.835
K90.9 Intestinal malabsorption, unspecified
0.000 0.183 0.817
E07 Other disorders of thyroid
0.000 0.210 0.790
E16.1 Other hypoglycaemia
0.000 0.235 0.765
E13.9 Without complications
0.000 0.264 0.736
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.715
L40.4 Guttate psoriasis
0.712 0.288 0.000
L40.2 Acrodermatitis continua
0.712 0.288 0.000
E05.8 Other thyrotoxicosis
0.000 0.288 0.712
E10.7 With multiple complications
0.000 0.291 0.709
L40.3 Pustulosis palmaris et plantaris
0.707 0.293 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.294 0.706
E10.0 With coma
0.000 0.303 0.697
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.303 0.697
E45 Retarded development following protein-energy malnutrition
0.000 0.303 0.697
E43 Unspecified severe protein-energy malnutrition
0.000 0.303 0.697
E42 Marasmic kwashiorkor
0.000 0.303 0.697
E41 Nutritional marasmus
0.000 0.303 0.697
E40 Kwashiorkor
0.000 0.303 0.697
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.328 0.672
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.334 0.666
L40.1 Generalised pustular psoriasis
0.661 0.339 0.000
E10.6 With other specified complications
0.000 0.349 0.651
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.353 0.647
K90.3 Pancreatic steatorrhoea
0.000 0.391 0.609
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.391 0.609
K90.1 Tropical sprue
0.000 0.391 0.609
E13.8 With unspecified complications
0.000 0.400 0.600
E13.7 With multiple complications
0.000 0.400 0.600
E13.6 With other specified complications
0.000 0.400 0.600
E13.5 With peripheral circulatory complications
0.000 0.400 0.600
E13.4 With neurological complications
0.000 0.400 0.600
E13.2 With renal complications
0.000 0.400 0.600
E13.1 With ketoacidosis
0.000 0.400 0.600
E13.0 With coma
0.000 0.400 0.600
E65-E68 Obesity and other hyperalimentation
0.000 0.420 0.580
E07.1 Dyshormogenetic goitre
0.000 0.433 0.567
E07.0 Hypersecretion of calcitonin
0.000 0.433 0.567
K90.8 Other intestinal malabsorption
0.000 0.434 0.566
E13.3 With ophthalmic complications
0.000 0.435 0.564
E20-E35 Disorders of other endocrine glands
0.000 0.453 0.547
E14 Unspecified diabetes mellitus
0.000 0.456 0.544
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E44.1 Mild protein-energy malnutrition
0.000 0.500 0.500
E44.0 Moderate protein-energy malnutrition
0.000 0.500 0.500
E06 Thyroiditis
0.000 0.510 0.490
E65 Localised adiposity
0.000 0.518 0.482
L40.0 Psoriasis vulgaris
0.478 0.522 0.000
E22 Hyperfunction of pituitary gland
0.000 0.524 0.476
E27 Other disorders of adrenal gland
0.000 0.529 0.471
E14.3 With ophthalmic complications
0.000 0.544 0.456
E26 Hyperaldosteronism
0.000 0.551 0.449
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.560 0.440
E14.8 With unspecified complications
0.000 0.575 0.425
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.580 0.420
E27.1 Primary adrenocortical insufficiency
0.000 0.582 0.418
E22.1 Hyperprolactinaemia
0.000 0.582 0.418
E67 Other hyperalimentation
0.000 0.584 0.416
E68 Sequelae of hyperalimentation
0.000 0.584 0.416
E14.6 With other specified complications
0.000 0.594 0.406
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.598 0.402
E14.4 With neurological complications
0.000 0.604 0.396
E50-E64 Other nutritional deficiencies
0.000 0.605 0.395
E07.8 Other specified disorders of thyroid
0.000 0.605 0.395
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.608 0.392
E32 Diseases of thymus
0.000 0.608 0.392
E30 Disorders of puberty, not elsewhere classified
0.000 0.608 0.392
E14.7 With multiple complications
0.000 0.609 0.390
E14.0 With coma
0.000 0.609 0.390
E25 Adrenogenital disorders
0.000 0.610 0.390
E14.2 Withrenal complications
0.000 0.613 0.387
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.623 0.377
E34 Other endocrine disorders
0.000 0.628 0.372
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.629 0.371
E26.0 Primary hyperaldosteronism
0.000 0.633 0.367
E14.5 With peripheral circulatory complications
0.000 0.640 0.360
E31 Polyglandular dysfunction
0.000 0.640 0.360
E29 Testicular dysfunction
0.000 0.643 0.357
E06.4 Drug-induced thyroiditis
0.000 0.648 0.351
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.648 0.351
E06.0 Acute thyroiditis
0.000 0.648 0.351
E24 Cushing's syndrome
0.000 0.648 0.352
E21.0 Primary hyperparathyroidism
0.000 0.650 0.350
E06.1 Subacute thyroiditis
0.000 0.650 0.350
E21.2 Other hyperparathyroidism
0.000 0.654 0.346
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.655 0.345
L40-L45 Papulosquamous disorders
0.343 0.656 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.659 0.341
E22.8 Other hyperfunction of pituitary gland
0.000 0.659 0.341
E26.9 Hyperaldosteronism, unspecified
0.000 0.660 0.340
E27.5 Adrenomedullary hyperfunction
0.000 0.662 0.338
E27.0 Other adrenocortical overactivity
0.000 0.662 0.338
E58 Dietary calcium deficiency
0.000 0.667 0.333
E27.9 Disorder of adrenal gland, unspecified
0.000 0.671 0.329
E03 Other hypothyroidism
0.000 0.672 0.328
E06.5 Other chronic thyroiditis
0.000 0.673 0.327
E06.3 Autoimmune thyroiditis
0.000 0.677 0.323
E26.8 Other hyperaldosteronism
0.000 0.678 0.322
E26.1 Secondary hyperaldosteronism
0.000 0.678 0.322
E27.2 Addisonian crisis
0.000 0.684 0.316
E21.4 Other specified disorders of parathyroid gland
0.000 0.684 0.316
E22.0 Acromegaly and pituitary gigantism
0.000 0.685 0.315
E34.8 Other specified endocrine disorders
0.000 0.687 0.313
E14.1 With ketoacidosis
0.000 0.694 0.305
E67.8 Other specified hyperalimentation
0.000 0.702 0.298
E67.3 Hypervitaminosis D
0.000 0.702 0.298
E67.2 Megavitamin-B6 syndrome
0.000 0.702 0.298
E67.1 Hypercarotenaemia
0.000 0.702 0.298
E67.0 Hypervitaminosis A
0.000 0.702 0.298
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.716 0.283
E63 Other nutritional deficiencies
0.000 0.716 0.283
E50 Vitamin A deficiency
0.000 0.716 0.283
E60 Dietary zinc deficiency
0.000 0.716 0.283
E59 Dietary selenium deficiency
0.000 0.716 0.283
E54 Ascorbic acid deficiency
0.000 0.716 0.283
E52 Niacin deficiency [pellagra]
0.000 0.716 0.283
E30.9 Disorder of puberty, unspecified
0.000 0.719 0.281
E30.8 Other disorders of puberty
0.000 0.719 0.281
E30.1 Precocious puberty
0.000 0.719 0.281
E30.0 Delayed puberty
0.000 0.719 0.281
E32.9 Disease of thymus, unspecified
0.000 0.719 0.281
E32.8 Other diseases of thymus
0.000 0.719 0.281
E32.1 Abscess of thymus
0.000 0.719 0.281
E32.0 Persistent hyperplasia of thymus
0.000 0.719 0.281
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.719 0.281
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.719 0.281
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.719 0.281
L42 Pityriasis rosea
0.280 0.720 0.000
E20 Hypoparathyroidism
0.000 0.720 0.280
E25.9 Adrenogenital disorder, unspecified
0.000 0.720 0.280
E25.8 Other adrenogenital disorders
0.000 0.720 0.280
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.722 0.278
E56 Other vitamin deficiencies
0.000 0.723 0.277
E34.0 Carcinoid syndrome
0.000 0.731 0.269
E34.5 Androgen resistance syndrome
0.000 0.733 0.267
E34.4 Constitutional tall stature
0.000 0.733 0.267
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.733 0.267
E34.1 Other hypersecretion of intestinal hormones
0.000 0.733 0.267
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.735 0.265
E24.8 Other Cushing's syndrome
0.000 0.737 0.263
E21.3 Hyperparathyroidism, unspecified
0.000 0.739 0.261
E31.9 Polyglandular dysfunction, unspecified
0.000 0.741 0.258
E31.8 Other polyglandular dysfunction
0.000 0.741 0.258
E31.1 Polyglandular hyperfunction
0.000 0.741 0.258
E24.0 Pituitary-dependent Cushing's disease
0.000 0.742 0.258
E29.9 Testicular dysfunction, unspecified
0.000 0.744 0.256
E29.8 Other testicular dysfunction
0.000 0.744 0.256
E29.0 Testicular hyperfunction
0.000 0.744 0.256
E03.8 Other specified hypothyroidism
0.000 0.746 0.254
E24.2 Drug-induced Cushing's syndrome
0.000 0.746 0.254
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.748 0.252
E24.3 Ectopic ACTH syndrome
0.000 0.748 0.252
E24.1 Nelson's syndrome
0.000 0.748 0.252
E27.8 Other specified disorders of adrenal gland
0.000 0.749 0.250
E51 Thiamine deficiency
0.000 0.749 0.250
L44 Other papulosquamous disorders
0.246 0.754 0.000
L41 Parapsoriasis
0.246 0.754 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.246 0.754 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.754 0.246
E06.9 Thyroiditis, unspecified
0.000 0.763 0.236
E03.5 Myxoedema coma
0.000 0.765 0.235
E03.4 Atrophy of thyroid (acquired)
0.000 0.765 0.235
E03.3 Postinfectious hypothyroidism
0.000 0.765 0.235
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.768 0.232
E55 Vitamin D deficiency
0.000 0.769 0.231
E31.0 Autoimmune polyglandular failure
0.000 0.773 0.226
E29.1 Testicular hypofunction
0.000 0.779 0.221
E03.1 Congenital hypothyroidism without goitre
0.000 0.781 0.219
E61 Deficiency of other nutrient elements
0.000 0.785 0.214
E50.9 Vitamin A deficiency, unspecified
0.000 0.796 0.203
E50.8 Other manifestations of vitamin A deficiency
0.000 0.796 0.203
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.796 0.203
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.796 0.203
E50.5 Vitamin A deficiency with night blindness
0.000 0.796 0.203
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.796 0.203
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.796 0.203
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.796 0.203
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.796 0.203
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.796 0.203
E63.9 Nutritional deficiency, unspecified
0.000 0.796 0.203
E63.8 Other specified nutritional deficiencies
0.000 0.796 0.203
E63.1 Imbalance of constituents of food intake
0.000 0.796 0.203
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.796 0.203
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.796 0.203
E64.8 Sequelae of other nutritional deficiencies
0.000 0.796 0.203
E64.3 Sequelae of rickets
0.000 0.796 0.203
E64.2 Sequelae of vitamin C deficiency
0.000 0.796 0.203
E64.1 Sequelae of vitamin A deficiency
0.000 0.796 0.203
E64.0 Sequelae of protein-energy malnutrition
0.000 0.796 0.203
E20.1 Pseudohypoparathyroidism
0.000 0.799 0.201
E20.0 Idiopathic hypoparathyroidism
0.000 0.799 0.201
E56.9 Vitamin deficiency, unspecified
0.000 0.801 0.199
E56.8 Deficiency of other vitamins
0.000 0.801 0.199
E56.0 Deficiency of vitamin E
0.000 0.801 0.199
E28 Ovarian dysfunction
0.001 0.801 0.198
E56.1 Deficiency of vitamin K
0.000 0.807 0.193
E34.9 Endocrine disorder, unspecified
0.000 0.815 0.185
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.816 0.184
E24.9 Cushing's syndrome, unspecified
0.000 0.817 0.183
E20.8 Other hypoparathyroidism
0.001 0.818 0.182
E51.9 Thiamine deficiency, unspecified
0.000 0.820 0.180
E51.8 Other manifestations of thiamine deficiency
0.000 0.820 0.180
E51.1 Beriberi
0.000 0.820 0.180
L41.9 Parapsoriasis, unspecified
0.177 0.823 0.000
L41.8 Other parapsoriasis
0.177 0.823 0.000
L41.5 Retiform parapsoriasis
0.177 0.823 0.000
L41.4 Large plaque parapsoriasis
0.177 0.823 0.000
L41.3 Small plaque parapsoriasis
0.177 0.823 0.000
L41.2 Lymphomatoid papulosis
0.177 0.823 0.000
L41.1 Pityriasis lichenoides chronica
0.177 0.823 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.177 0.823 0.000
L44.9 Papulosquamous disorder, unspecified
0.177 0.823 0.000
L44.8 Other specified papulosquamous disorders
0.177 0.823 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.177 0.823 0.000
L44.3 Lichen ruber moniliformis
0.177 0.823 0.000
L44.2 Lichen striatus
0.177 0.823 0.000
L44.1 Lichen nitidus
0.177 0.823 0.000
L44.0 Pityriasis rubra pilaris
0.177 0.823 0.000
E55.0 Rickets, active
0.000 0.834 0.166
E53 Deficiency of other B group vitamins
0.000 0.843 0.157
E61.9 Deficiency of nutrient element, unspecified
0.000 0.846 0.154
E61.8 Deficiency of other specified nutrient elements
0.000 0.846 0.154
E61.7 Deficiency of multiple nutrient elements
0.000 0.846 0.154
E61.6 Vanadium deficiency
0.000 0.846 0.154
E61.5 Molybdenum deficiency
0.000 0.846 0.154
E61.4 Chromium deficiency
0.000 0.846 0.154
E61.3 Manganese deficiency
0.000 0.846 0.154
E61.0 Copper deficiency
0.000 0.846 0.154
E23 Hypofunction and other disorders of pituitary gland
0.000 0.849 0.150
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.147 0.853 0.000
E51.2 Wernicke's encephalopathy
0.000 0.853 0.146
C91.1 Chronic lymphocytic leukaemia
0.000 0.855 0.145
E28.9 Ovarian dysfunction, unspecified
0.001 0.857 0.142
E28.8 Other ovarian dysfunction
0.001 0.857 0.142
E28.1 Androgen excess
0.001 0.857 0.142
E28.0 Oestrogen excess
0.001 0.857 0.142
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.142 0.858 0.000
L43 Lichen planus
0.141 0.859 0.000
T39.1 4-Aminophenol derivatives
0.139 0.861 0.000
E61.2 Magnesium deficiency
0.000 0.866 0.134
E20.9 Hypoparathyroidism, unspecified
0.001 0.874 0.125
E61.1 Iron deficiency
0.000 0.883 0.117
E53.1 Pyridoxine deficiency
0.000 0.887 0.113
E53.0 Riboflavin deficiency
0.000 0.887 0.113
E55.9 Vitamin D deficiency, unspecified
0.000 0.887 0.113
E28.3 Primary ovarian failure
0.001 0.889 0.111
T39.0 Salicylates
0.109 0.891 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.892 0.108
E23.1 Drug-induced hypopituitarism
0.000 0.892 0.108
E23.7 Disorder of pituitary gland, unspecified
0.000 0.893 0.107
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.107 0.893 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.895 0.105
T39.4 Antirheumatics, not elsewhere classified
0.102 0.898 0.000
T39.2 Pyrazolone derivatives
0.102 0.898 0.000
L43.3 Subacute (active) lichen planus
0.101 0.899 0.000
L43.2 Lichenoid drug reaction
0.101 0.899 0.000
L43.1 Bullous lichen planus
0.101 0.899 0.000
L43.0 Hypertrophic lichen planus
0.101 0.899 0.000
E14.9 Without complications
0.000 0.902 0.098
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.097 0.902 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.097 0.903 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.095 0.905 0.000
L43.8 Other lichen planus
0.092 0.908 0.000
E04 Other non-toxic goitre
0.000 0.911 0.089
T43.3 Phenothiazine antipsychotics and neuroleptics
0.089 0.911 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.085 0.915 0.000
T43.2 Other and unspecified antidepressants
0.085 0.915 0.000
E23.2 Diabetes insipidus
0.000 0.917 0.083
T43.5 Other and unspecified antipsychotics and neuroleptics
0.081 0.919 0.000
E23.6 Other disorders of pituitary gland
0.000 0.925 0.075
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.075 0.925 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.074 0.925 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.074 0.925 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.074 0.926 0.000
T36 Poisoning by systemic antibiotics
0.073 0.927 0.000
T43.6 Psychostimulants with abuse potential
0.073 0.927 0.000
E66 Obesity
0.000 0.928 0.072
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.072 0.928 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.070 0.930 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.070 0.930 0.000
T43.9 Psychotropic drug, unspecified
0.068 0.932 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.068 0.932 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.068 0.932 0.000
R06.8 Other and unspecified abnormalities of breathing
0.067 0.933 0.000
T42.1 Iminostilbenes
0.067 0.933 0.000
T42.4 Benzodiazepines
0.067 0.933 0.000
E04.8 Other specified non-toxic goitre
0.000 0.936 0.064
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.063 0.937 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.062 0.938 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.062 0.938 0.000
T47.2 Stimulant laxatives
0.062 0.938 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.061 0.938 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.061 0.939 0.000
T42.2 Succinimides and oxazolidinediones
0.061 0.939 0.000
T42.0 Hydantoin derivatives
0.060 0.940 0.000
T38.1 Thyroid hormones and substitutes
0.060 0.940 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.059 0.941 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.058 0.942 0.000
T42.3 Barbiturates
0.056 0.944 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.055 0.944 0.000
T36.3 Macrolides
0.055 0.945 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.055 0.945 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.055 0.945 0.000
K90-K93 Other diseases of the digestive system
0.000 0.945 0.055
T47.0 Histamine H(2)-receptor antagonists
0.054 0.945 0.000
T47.4 Other laxatives
0.054 0.946 0.000
T38.9 Other and unspecified hormone antagonists
0.054 0.946 0.000
T38.7 Androgens and anabolic congeners
0.054 0.946 0.000
T38.5 Other oestrogens and progestogens
0.054 0.946 0.000
T38.4 Oral contraceptives
0.054 0.946 0.000
T38.2 Antithyroid drugs
0.054 0.946 0.000
T38.0 Glucocorticoids and synthetic analogues
0.054 0.946 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.054 0.946 0.000
T37.5 Antiviral drugs
0.054 0.946 0.000
T37.4 Anthelminthics
0.054 0.946 0.000
T37.3 Other antiprotozoal drugs
0.054 0.946 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.054 0.946 0.000
T37.1 Antimycobacterial drugs
0.054 0.946 0.000
T37.0 Sulphonamides
0.054 0.946 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.053 0.946 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.053 0.946 0.000
T47.7 Emetics
0.053 0.946 0.000
T47.6 Antidiarrhoeal drugs
0.053 0.946 0.000
T47.5 Digestants
0.053 0.946 0.000
T47.3 Saline and osmotic laxatives
0.053 0.946 0.000
T36.0 Penicillins
0.054 0.946 0.000
T36.9 Systemic antibiotic, unspecified
0.053 0.947 0.000
T36.8 Other systemic antibiotics
0.053 0.947 0.000
T36.7 Antifungal antibiotics, systemically used
0.053 0.947 0.000
T36.6 Rifamycins
0.053 0.947 0.000
T36.5 Aminoglycosides
0.053 0.947 0.000
T36.4 Tetracyclines
0.053 0.947 0.000
T36.2 Chloramphenicol group
0.053 0.947 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.053 0.947 0.000
E66.1 Drug-induced obesity
0.000 0.948 0.052
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.052 0.948 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.051 0.949 0.000
E23.0 Hypopituitarism
0.000 0.949 0.051
T49.9 Topical agent, unspecified
0.051 0.949 0.000
T49.8 Other topical agents
0.051 0.949 0.000
T49.7 Dental drugs, topically applied
0.051 0.949 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.051 0.949 0.000
T49.5 Ophthalmological drugs and preparations
0.051 0.949 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.051 0.949 0.000
T49.3 Emollients, demulcents and protectants
0.051 0.949 0.000
T49.2 Local astringents and local detergents
0.051 0.949 0.000
T49.1 Antipruritics
0.051 0.949 0.000
T41.5 Therapeutic gases
0.050 0.950 0.000
T41.4 Anaesthetic, unspecified
0.050 0.950 0.000
T41.3 Local anaesthetics
0.050 0.950 0.000
T41.2 Other and unspecified general anaesthetics
0.050 0.950 0.000
T41.1 Intravenous anaesthetics
0.050 0.950 0.000
T41.0 Inhaled anaesthetics
0.050 0.950 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.950 0.050
H36.0 Diabetic retinopathy
0.000 0.952 0.048
T38.8 Other and unspecified hormones and their synthetic substitutes
0.048 0.952 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.046 0.954 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.046 0.954 0.000
E66.0 Obesity due to excess calories
0.000 0.954 0.046
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.046 0.954 0.000
T48.5 Anti-common-cold drugs
0.046 0.954 0.000
T48.4 Expectorants
0.046 0.954 0.000
T48.3 Antitussives
0.046 0.954 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.046 0.954 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.046 0.954 0.000
T48.0 Oxytocic drugs
0.046 0.954 0.000
T45.0 Antiallergic and antiemetic drugs
0.045 0.955 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.045 0.955 0.000
T45.8 Other primarily systemic and haematological agents
0.045 0.955 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.045 0.955 0.000
T45.6 Fibrinolysis-affecting drugs
0.045 0.955 0.000
T45.4 Iron and its compounds
0.045 0.955 0.000
T45.3 Enzymes, not elsewhere classified
0.045 0.955 0.000
T50.1 Loop [high-ceiling] diuretics
0.044 0.956 0.000
T45.5 Anticoagulants
0.043 0.957 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.957 0.042
T46.5 Other antihypertensive drugs, not elsewhere classified
0.042 0.957 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.042 0.958 0.000
C91 Lymphoid leukaemia
0.000 0.958 0.042
T50.8 Diagnostic agents
0.042 0.958 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.041 0.959 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.041 0.959 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.041 0.959 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.040 0.959 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.040 0.960 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.040 0.960 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.040 0.960 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.040 0.960 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.040 0.960 0.000
T44.0 Anticholinesterase agents
0.040 0.960 0.000
T50.7 Analeptics and opioid receptor antagonists
0.040 0.960 0.000
T50.5 Appetite depressants
0.040 0.960 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.040 0.960 0.000
T50.0 Mineralocorticoids and their antagonists
0.040 0.960 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.040 0.960 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.039 0.960 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.039 0.960 0.000
T46.7 Peripheral vasodilators
0.039 0.960 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.960 0.039
T48.6 Antiasthmatics, not elsewhere classified
0.039 0.961 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.039 0.961 0.000
E28.2 Polycystic ovarian syndrome
0.001 0.961 0.037
T50.4 Drugs affecting uric acid metabolism
0.038 0.962 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.038 0.962 0.000
T45.2 Vitamins, not elsewhere classified
0.037 0.963 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.036 0.964 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.035 0.965 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.034 0.966 0.000
C91.0 Acute lymphoblastic leukaemia
0.000 0.967 0.033
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.970 0.030
C91.7 Other lymphoid leukaemia
0.000 0.970 0.030
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.970 0.030
C91.3 Prolymphocytic leukaemia
0.000 0.970 0.030
C91.2 Subacute lymphocytic leukaemia
0.000 0.970 0.030
E11 Non-insulin-dependent diabetes mellitus
0.000 0.970 0.030
C91.5 Adult T-cell leukaemia
0.000 0.970 0.029
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.971 0.028
K93.1 Megacolon in Chagas' disease
0.000 0.971 0.028
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.971 0.028
C91.9 Lymphoid leukaemia, unspecified
0.000 0.972 0.028
T46.1 Calcium-channel blockers
0.028 0.972 0.000
T40.1 Heroin
0.028 0.972 0.000
E11.5 With peripheral circulatory complications
0.000 0.972 0.028
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.028 0.972 0.000
T40.8 Lysergide [LSD]
0.028 0.972 0.000
T40.7 Cannabis (derivatives)
0.028 0.972 0.000
T40.3 Methadone
0.028 0.972 0.000
T40.0 Opium
0.028 0.972 0.000
T40.6 Other and unspecified narcotics
0.027 0.972 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.974 0.026
E04.0 Non-toxic diffuse goitre
0.001 0.974 0.025
T40.4 Other synthetic narcotics
0.026 0.974 0.000
T40.5 Cocaine
0.025 0.975 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.977 0.023
R06 Abnormalities of breathing
0.023 0.977 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.023 0.977 0.000
L43.9 Lichen planus, unspecified
0.022 0.978 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.022 0.978 0.000
E11.7 With multiple complications
0.000 0.978 0.022
R06.1 Stridor
0.021 0.979 0.000
M07.3 Other psoriatic arthropathies
0.021 0.979 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.979 0.021
T43.0 Tricyclic and tetracyclic antidepressants
0.020 0.980 0.000
R06.5 Mouth breathing
0.020 0.980 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.020 0.980 0.000
J33.8 Other polyp of sinus
0.000 0.981 0.019
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.018 0.982 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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