TreeWAS – Variant ID: rs58263042

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G30.9 Alzheimer's disease, unspecified	0.029	0.971	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.024	0.976	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.024	0.976	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.024	0.976	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.023	0.976	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.022	0.978	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.978	0.022
G06.0 Intracranial abscess and granuloma	0.021	0.979	0.000
O80.0 Spontaneous vertex delivery	0.021	0.979	0.000
F03 Unspecified dementia	0.021	0.979	0.000
G30 Alzheimer's disease	0.020	0.980	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.020	0.980	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.020	0.980	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.020	0.980	0.000
F00 Dementia in Alzheimer's disease	0.020	0.980	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.019	0.981	0.000
G03 Meningitis due to other and unspecified causes	0.018	0.981	0.000
R52.1 Chronic intractable pain	0.000	0.982	0.018
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.018	0.982	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.017	0.982	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.017	0.983	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.017	0.983	0.000
G04.1 Tropical spastic paraplegia	0.017	0.983	0.000
G04.0 Acute disseminated encephalitis	0.017	0.983	0.000
G00 Bacterial meningitis, not elsewhere classified	0.017	0.983	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.017	0.983	0.000
F02 Dementia in other diseases classified elsewhere	0.016	0.983	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.016	0.984	0.000
F01 Vascular dementia	0.016	0.984	0.000
G30.0 Alzheimer's disease with early onset	0.016	0.984	0.000
G06.2 Extradural and subdural abscess, unspecified	0.016	0.984	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.016	0.984	0.000
F05.9 Delirium, unspecified	0.016	0.984	0.000
G06.1 Intraspinal abscess and granuloma	0.016	0.984	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.015	0.985	0.000
G30.8 Other Alzheimer's disease	0.015	0.985	0.000
G30.1 Alzheimer's disease with late onset	0.015	0.985	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.015	0.985	0.000
F09 Unspecified organic or symptomatic mental disorder	0.015	0.985	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.015	0.985	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.015	0.985	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.015	0.985	0.000
F07.2 Postconcussional syndrome	0.014	0.985	0.000
G03.9 Meningitis, unspecified	0.014	0.985	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.014	0.986	0.000
F02.0 Dementia in Pick's disease	0.014	0.986	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.014	0.986	0.000
G02.1 Meningitis in mycoses	0.014	0.986	0.000
G03.8 Meningitis due to other specified causes	0.013	0.986	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.013	0.986	0.000
G03.1 Chronic meningitis	0.013	0.986	0.000
G03.0 Nonpyogenic meningitis	0.013	0.986	0.000
F05.0 Delirium not superimposed on dementia, so described	0.013	0.986	0.000
F01.9 Vascular dementia, unspecified	0.013	0.987	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.013	0.987	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.013	0.987	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.013	0.987	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.013	0.987	0.000
F05.1 Delirium superimposed on dementia	0.013	0.987	0.000
G00.9 Bacterial meningitis, unspecified	0.012	0.987	0.000
G00.8 Other bacterial meningitis	0.012	0.988	0.000
G00.3 Staphylococcal meningitis	0.012	0.988	0.000
G00.2 Streptococcal meningitis	0.012	0.988	0.000
G00.0 Haemophilus meningitis	0.012	0.988	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.012	0.988	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.012	0.988	0.000
F07.1 Postencephalitic syndrome	0.012	0.988	0.000
F07.0 Organic personality disorder	0.012	0.988	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.012	0.988	0.000
F02.2 Dementia in Huntington's disease	0.012	0.988	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.012	0.988	0.000
F02.3 Dementia in Parkinson's disease	0.012	0.988	0.000
G30-G32 Other degenerative diseases of the nervous system	0.012	0.988	0.000
F01.8 Other vascular dementia	0.012	0.988	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.012	0.988	0.000
F01.2 Subcortical vascular dementia	0.012	0.988	0.000
F01.1 Multi-infarct dementia	0.012	0.988	0.000
F01.0 Vascular dementia of acute onset	0.012	0.988	0.000
G00.1 Pneumococcal meningitis	0.012	0.988	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.011	0.988	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.011	0.988	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.989	0.011
D69 Purpura and other haemorrhagic conditions	0.000	0.989	0.011
F05.8 Other delirium	0.011	0.989	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.010	0.989	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.010	0.989	0.000
F06.5 Organic dissociative disorder	0.010	0.989	0.000
F06.4 Organic anxiety disorder	0.010	0.989	0.000
F06.3 Organic mood [affective] disorders	0.010	0.989	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.010	0.989	0.000
F06.1 Organic catatonic disorder	0.010	0.989	0.000
F06.0 Organic hallucinosis	0.010	0.989	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.010	0.990	0.000
G31.8 Other specified degenerative diseases of nervous system	0.009	0.991	0.000
G31.0 Circumscribed brain atrophy	0.009	0.991	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.009	0.991	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.991	0.009
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.991	0.009
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.991	0.009
F06.7 Mild cognitive disorder	0.008	0.991	0.000
R47.1 Dysarthria and anarthria	0.000	0.991	0.009
D69.9 Haemorrhagic condition, unspecified	0.000	0.992	0.008
O80 Single spontaneous delivery	0.008	0.992	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.992	0.008
D69.2 Other nonthrombocytopenic purpura	0.000	0.992	0.008
D69.1 Qualitative platelet defects	0.000	0.992	0.008
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.992	0.008
S62.60 Fracture of other finger (closed)	0.008	0.992	0.000
N85.4 Malposition of uterus	0.008	0.992	0.000
D69.5 Secondary thrombocytopenia	0.000	0.992	0.008
D69.0 Allergic purpura	0.000	0.992	0.008
G31.1 Senile degeneration of brain, not elsewhere classified	0.007	0.992	0.000
D69.4 Other primary thrombocytopenia	0.000	0.993	0.007
R47.0 Dysphasia and aphasia	0.000	0.993	0.007
Y43.3 Other antineoplastic drugs	0.000	0.993	0.007
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.006	0.993	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.006	0.993	0.000
T86 Failure and rejection of transplanted organs and tissues	0.000	0.993	0.007
G31.2 Degeneration of nervous system due to alcohol	0.006	0.993	0.000
I44.0 Atrioventricular block, first degree	0.006	0.994	0.000
T86.0 Bone-marrow transplant rejection	0.000	0.994	0.006
O80.1 Spontaneous breech delivery	0.006	0.994	0.000
O80-O84 Delivery	0.006	0.994	0.000
O81 Single delivery by forceps and vacuum extractor	0.006	0.994	0.000
T86.1 Kidney transplant failure and rejection	0.000	0.994	0.006
G31.9 Degenerative disease of nervous system, unspecified	0.006	0.994	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.006	0.994	0.000
O81.4 Vacuum extractor delivery	0.006	0.994	0.000
K60.3 Anal fistula	0.000	0.994	0.006
O81.3 Other and unspecified forceps delivery	0.005	0.995	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.995	0.005
Y43 Primarily systemic agents	0.000	0.995	0.005
Y45.1 Salicylates	0.000	0.995	0.005
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.995	0.005
T86.4 Liver transplant failure and rejection	0.000	0.995	0.005
T86.3 Heart-lung transplant failure and rejection	0.000	0.995	0.005
T86.2 Heart transplant failure and rejection	0.000	0.995	0.005
O82 Single delivery by Caesarean section	0.005	0.995	0.000
R52 Pain, not elsewhere classified	0.000	0.995	0.005
R52.2 Other chronic pain	0.000	0.995	0.005
O84 Multiple delivery	0.004	0.995	0.000
O83 Other assisted single delivery	0.004	0.995	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.004	0.995	0.000
O81.2 Mid-cavity forceps with rotation	0.004	0.995	0.000
O81.1 Mid-cavity forceps delivery	0.004	0.995	0.000
O82.9 Delivery by Caesarean section, unspecified	0.004	0.995	0.000
O81.0 Low forceps delivery	0.004	0.995	0.000
Y43.1 Antineoplastic antimetabolites	0.000	0.996	0.004
Y45.5 4-Aminophenol derivatives	0.000	0.996	0.004
O80.8 Other single spontaneous delivery	0.004	0.996	0.000
Y43.0 Antiallergic and antiemetic drugs	0.000	0.996	0.004
Y43.4 Immunosuppressive agents	0.000	0.996	0.004
Y43.9 Primarily systemic agent, unspecified	0.000	0.996	0.004
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.996	0.004
Y43.6 Enzymes, not elsewhere classified	0.000	0.996	0.004
Y43.5 Acidifying and alkalising agents	0.000	0.996	0.004
Y43.2 Antineoplastic natural products	0.000	0.996	0.004
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.996	0.004
Y45.4 Antirheumatics	0.000	0.996	0.004
K31.9 Disease of stomach and duodenum, unspecified	0.000	0.996	0.004
K31.7 Polyp of stomach and duodenum	0.000	0.996	0.004
Y45.8 Other analgesics and antipyretics	0.000	0.996	0.004
O82.8 Other single delivery by Caesarean section	0.004	0.996	0.000
O82.2 Delivery by Caesarean hysterectomy	0.004	0.996	0.000
H52.0 Hypermetropia	0.004	0.996	0.000
C15.5 Lower third of oesophagus	0.004	0.996	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.996	0.004
O83.9 Assisted single delivery, unspecified	0.003	0.996	0.000
O83.8 Other specified assisted single delivery	0.003	0.996	0.000
O83.4 Destructive operation for delivery	0.003	0.996	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.003	0.996	0.000
O83.2 Other manipulation-assisted delivery	0.003	0.996	0.000
O83.1 Other assisted breech delivery	0.003	0.996	0.000
O83.0 Breech extraction	0.003	0.996	0.000
O84.9 Multiple delivery, unspecified	0.003	0.996	0.000
O84.8 Other multiple delivery	0.003	0.996	0.000
O84.2 Multiple delivery, all by Caesarean section	0.003	0.996	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.003	0.996	0.000
O84.0 Multiple delivery, all spontaneous	0.003	0.996	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.004	0.996	0.000
O82.1 Delivery by emergency Caesarean section	0.003	0.997	0.000
O82.0 Delivery by elective Caesarean section	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.997	0.003
Y45.2 Propionic acid derivatives	0.000	0.997	0.003
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.997	0.003
A04.8 Other specified bacterial intestinal infections	0.003	0.997	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.997	0.003
N90.7 Vulvar cyst	0.000	0.997	0.003
R94.3 Abnormal results of cardiovascular function studies	0.003	0.997	0.000
O80.9 Single spontaneous delivery, unspecified	0.003	0.997	0.000
Y45.0 Opioids and related analgesics	0.000	0.997	0.003
Y57 Other and unspecified drugs and medicaments	0.000	0.997	0.003
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.997	0.003
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.997	0.003
S62.6 Fracture of other finger	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.997	0.003
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
D67 Hereditary factor IX deficiency	0.000	0.997	0.003
D66 Hereditary factor VIII deficiency	0.000	0.997	0.003
Y57.9 Drug or medicament, unspecified	0.000	0.997	0.003
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.997	0.003
C73 Malignant neoplasm of thyroid gland	0.003	0.997	0.000
Y53.4 Other laxatives	0.000	0.997	0.002
Y57.8 Other drugs and medicaments	0.000	0.997	0.002
I05.0 Mitral stenosis	0.000	0.997	0.002
K31 Other diseases of stomach and duodenum	0.000	0.997	0.003
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.997	0.002
Y54.5 Other diuretics	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.000	0.998	0.002
Y58 Bacterial vaccines	0.000	0.998	0.002
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
L29.0 Pruritus ani	0.000	0.998	0.002
Y49.2 Other and unspecified antidepressants	0.000	0.998	0.002
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.998	0.002
C15.4 Middle third of oesophagus	0.002	0.998	0.000
N13.4 Hydroureter	0.000	0.998	0.002
Z74.0 Reduced mobility	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.002	0.998	0.000
N70.1 Chronic salpingitis and oophoritis	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.998	0.002
Y52 Agents primarily affecting the cardiovascular system	0.000	0.998	0.002
C15.3 Upper third of oesophagus	0.002	0.998	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.998	0.002
N42.8 Other specified disorders of prostate	0.002	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
Y53.7 Emetics	0.000	0.998	0.002
Y53.6 Antidiarrhoeal drugs	0.000	0.998	0.002
Y53.5 Digestants	0.000	0.998	0.002
Y53.3 Saline and osmotic laxatives	0.000	0.998	0.002
Y53.2 Stimulant laxatives	0.000	0.998	0.002
Y53.0 Histamine H2-receptor antagonists	0.000	0.998	0.002
Y57.7 Vitamins, not elsewhere classified	0.000	0.998	0.002
Y57.6 Other diagnostic agents	0.000	0.998	0.002
Y57.4 Pharmaceutical excipients	0.000	0.998	0.002
Y57.3 Alcohol deterrents	0.000	0.998	0.002
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
Y57.1 Lipotropic drugs	0.000	0.998	0.002
Y57.0 Appetite depressants [anorectics]	0.000	0.998	0.002
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
K31.1 Adult hypertrophic pyloric stenosis	0.000	0.998	0.002
N13 Obstructive and reflux uropathy	0.000	0.998	0.002
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.998	0.002
N42.1 Congestion and haemorrhage of prostate	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.000	0.998	0.002
R52.0 Acute pain	0.001	0.998	0.002
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.998	0.002
C82.0 Small cleaved cell, follicular	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.000	0.998	0.002
Y49.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
Y49.7 Psychostimulants with abuse potential	0.000	0.998	0.002
Y49.6 Psychodysleptics [hallucinogens]	0.000	0.998	0.002
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
Y57.5 X-ray contrast media	0.000	0.998	0.002
D86 Sarcoidosis	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.000	0.998	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
Y41.4 Anthelminthics	0.000	0.998	0.002
Y41.3 Other antiprotozoal drugs	0.000	0.998	0.002
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
Y41.1 Antimycobacterial drugs	0.000	0.998	0.002
Y41.0 Sulphonamides	0.000	0.998	0.002
Y47.1 Benzodiazepines	0.000	0.998	0.002
Y49.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
R47-R49 Symptoms and signs involving speech and voice	0.000	0.998	0.002
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
W22.9 Unspecified place	0.000	0.998	0.002
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
D68 Other coagulation defects	0.000	0.998	0.002
S72.30 Fracture of shaft of femur (closed)	0.000	0.998	0.002
K31.6 Fistula of stomach and duodenum	0.000	0.998	0.002
K31.3 Pylorospasm, not elsewhere classified	0.000	0.998	0.002
K31.2 Hourglass stricture and stenosis of stomach	0.000	0.998	0.002
K31.0 Acute dilatation of stomach	0.000	0.998	0.002
R52.9 Pain, unspecified	0.001	0.998	0.001
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.998	0.002
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.998	0.002
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.998	0.002
Y47.4 Bromine compounds	0.000	0.998	0.002
Y47.3 Paraldehyde	0.000	0.998	0.002
Y47.2 Chloral derivatives	0.000	0.998	0.002
Y47.0 Barbiturates, not elsewhere classified	0.000	0.998	0.002
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.998	0.002
K31.4 Gastric diverticulum	0.000	0.998	0.002
H52.2 Astigmatism	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
S20.3 Other superficial injuries of front wall of thorax	0.002	0.998	0.000
S20.2 Contusion of thorax	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.000	0.998	0.002
Y50.8 Other central nervous system stimulants	0.000	0.998	0.002
Y50.2 Methylxanthines, not elsewhere classified	0.000	0.998	0.002
Y50.1 Opioid receptor antagonists	0.000	0.998	0.002
Y50.0 Analeptics	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
Y55.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
Y55.5 Anticommon cold drugs	0.000	0.998	0.002
Y55.4 Expectorants	0.000	0.998	0.002
Y55.3 Antitussives	0.000	0.998	0.002
Y55.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
Y55.0 Oxytocic drugs	0.000	0.998	0.002
Y58.9 Other and unspecified bacterial vaccines	0.000	0.998	0.002
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.000	0.998	0.002
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.000	0.998	0.002
Y58.5 Diphtheria vaccine	0.000	0.998	0.002
Y58.4 Tetanus vaccine	0.000	0.998	0.002
Y58.3 Plague vaccine	0.000	0.998	0.002
Y58.2 Cholera vaccine	0.000	0.998	0.002
Y58.1 Typhoid and paratyphoid vaccine	0.000	0.998	0.002
Y58.0 BCG vaccine	0.000	0.998	0.002
Y59.9 Vaccine or biological substance, unspecified	0.000	0.998	0.002
Y59.8 Other specified vaccines and biological substances	0.000	0.998	0.002
Y59.3 Immunoglobulin	0.000	0.998	0.002
Y59.2 Protozoal vaccines	0.000	0.998	0.002
Y59.1 Rickettsial vaccines	0.000	0.998	0.002
Y59.0 Viral vaccines	0.000	0.998	0.002
S20 Superficial injury of thorax	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.000	0.998	0.002
G72.9 Myopathy, unspecified	0.000	0.998	0.002
K22.2 Oesophageal obstruction	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.000	0.998	0.002
C15.8 Overlapping lesion of oesophagus	0.002	0.998	0.000
C15.2 Abdominal part of oesophagus	0.002	0.998	0.000
C15.1 Thoracic part of oesophagus	0.002	0.998	0.000
C15.0 Cervical part of oesophagus	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.000	0.998	0.002
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.998	0.002
Y54.0 Mineralocorticoids	0.000	0.998	0.002
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
Y48 Anaesthetics and therapeutic gases	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
Y52.7 Peripheral vasodilators	0.000	0.998	0.002
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
Y56.9 Topical agent, unspecified	0.000	0.998	0.002
Y56.8 Other topical agents	0.000	0.998	0.002
Y56.7 Dental drugs, topically applied	0.000	0.998	0.002
Y56.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
Y56.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
Y56.3 Emollients, demulcents and protectants	0.000	0.998	0.002
Y56.2 Local astringents and local detergents	0.000	0.998	0.002
Y56.1 Antipruritics	0.000	0.998	0.002
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.002
Chapter VI Diseases of the nervous system	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.002
M35.3 Polymyalgia rheumatica	0.002	0.998	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.998	0.002
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.998	0.002
Y46.8 Antispasticity drugs	0.000	0.998	0.002
Y46.7 Anti-Parkinsonism drugs	0.000	0.998	0.002
Y46.5 Valproic acid	0.000	0.998	0.002
Y46.4 Iminostilbenes	0.000	0.998	0.002
Y46.3 Deoxybarbiturates	0.000	0.998	0.002
Y46.1 Oxazolidinediones	0.000	0.998	0.002
Y46.0 Succinimides	0.000	0.998	0.002
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.002	0.998	0.000
C82.2 Large cell, follicular	0.002	0.998	0.000
I05.8 Other mitral valve diseases	0.000	0.998	0.002
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
G71.0 Muscular dystrophy	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.002
Y54.4 Loop [high-ceiling] diuretics	0.000	0.998	0.002
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
Y54.3 Benzothiadiazine derivatives	0.000	0.998	0.002
Y44 Agents primarily affecting blood constituents	0.000	0.998	0.002
N34.2 Other urethritis	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.000	0.998	0.002
G71 Primary disorders of muscles	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.000	0.998	0.002
D68.4 Acquired coagulation factor deficiency	0.000	0.998	0.002
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.998	0.002
C82.4 Follicular lymphoma grade IIIb	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.000	0.998	0.002
D47.2 Monoclonal gammopathy	0.000	0.998	0.002
I50.9 Heart failure, unspecified	0.002	0.998	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.998	0.002
I49.8 Other specified cardiac arrhythmias	0.000	0.998	0.002
S20.7 Multiple superficial injuries of thorax	0.002	0.998	0.000
S20.4 Other superficial injuries of back wall of thorax	0.002	0.998	0.000
S20.1 Other and unspecified superficial injuries of breast	0.002	0.998	0.000
S20.0 Contusion of breast	0.002	0.998	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.998	0.002
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.002	0.998	0.000
Z74.1 Need for assistance with personal care	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.000	0.998	0.001
Y48.1 Parenteral anaesthetics	0.000	0.998	0.001
Y48.0 Inhaled anaesthetics	0.000	0.998	0.001
H80 Otosclerosis	0.000	0.998	0.002
G70-G73 Diseases of myoneural junction and muscle	0.001	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.998	0.002
G71.3 Mitochondrial myopathy, not elsewhere classified	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.000	0.998	0.002
H52 Disorders of refraction and accommodation	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.000	0.998	0.001
C82.6 Cutaneous follicle centre lymphoma	0.002	0.998	0.000
C82.5 Diffuse follicle centre lymphoma	0.002	0.998	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.998	0.002
G72 Other myopathies	0.001	0.998	0.001
D68.6 Other Thrombophilia	0.000	0.998	0.002
Y48.2 Other and unspecified general anaesthetics	0.000	0.998	0.001
Z71.8 Other specified counselling	0.002	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.001
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.998	0.001
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.998	0.001
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.998	0.001
G71.1 Myotonic disorders	0.001	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.001
C82.3 Follicular lymphoma grade IIIa	0.001	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.998	0.001
H92.1 Otorrhoea	0.000	0.998	0.002
G71.9 Primary disorder of muscle, unspecified	0.001	0.998	0.000
G71.8 Other primary disorders of muscles	0.001	0.998	0.000
G71.2 Congenital myopathies	0.001	0.998	0.000
I44.6 Other and unspecified fascicular block	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.001	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.000	0.998	0.001
Y44.7 Plasma substitutes	0.000	0.998	0.001
Y44.6 Natural blood and blood products	0.000	0.998	0.001
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.000	0.998	0.001
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.000	0.998	0.001
Y48.3 Local anaesthetics	0.000	0.998	0.001
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.001	0.998	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.998	0.002
F22.0 Delusional disorder	0.002	0.998	0.000
L29.8 Other pruritus	0.000	0.998	0.002
R48.8 Other and unspecified symbolic dysfunctions	0.000	0.998	0.001
R48.2 Apraxia	0.000	0.998	0.001
R48.1 Agnosia	0.000	0.998	0.001
R48.0 Dyslexia and alexia	0.000	0.998	0.001
Y44.5 Thrombolytic drugs	0.000	0.998	0.001
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.001	0.998	0.000
G14 Postpolio syndrome	0.001	0.998	0.000
Z74 Problems related to care-provider dependency	0.002	0.998	0.000
D43.0 Brain, supratentorial	0.001	0.998	0.000
I49.5 Sick sinus syndrome	0.000	0.998	0.002
N60.1 Diffuse cystic mastopathy	0.000	0.998	0.002
Y60.4 During endoscopic examination	0.001	0.998	0.000
Y60.0 During surgical operation	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.001
H80.8 Other otosclerosis	0.000	0.998	0.001
H80.2 Cochlear otosclerosis	0.000	0.998	0.001
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.998	0.001
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.998	0.001
Z43.3 Attention to colostomy	0.000	0.998	0.001
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.001	0.998	0.000
H52.6 Other disorders of refraction	0.001	0.999	0.000
H52.5 Disorders of accommodation	0.001	0.999	0.000
H52.4 Presbyopia	0.001	0.999	0.000
K02.9 Dental caries, unspecified	0.000	0.999	0.001
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.999	0.001
Q50.4 Embryonic cyst of Fallopian tube	0.001	0.999	0.000
G72.8 Other specified myopathies	0.001	0.999	0.001
G72.3 Periodic paralysis	0.001	0.999	0.001
G72.2 Myopathy due to other toxic agents	0.001	0.999	0.001
G72.1 Alcoholic myopathy	0.001	0.999	0.001
Y48.4 Anaesthetic, unspecified	0.001	0.999	0.001
Y60.6 During aspiration, puncture and other catheterisation	0.001	0.999	0.000
G11 Hereditary ataxia	0.001	0.999	0.000
L29 Pruritus	0.000	0.999	0.001
C15.9 Oesophagus, unspecified	0.001	0.999	0.000
D68.8 Other specified coagulation defects	0.000	0.999	0.001
G72.0 Drug-induced myopathy	0.001	0.999	0.001
Q67.6 Pectus excavatum	0.001	0.999	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.999	0.001
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.999	0.001
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.001	0.999	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.999	0.001
G11.4 Hereditary spastic paraplegia	0.001	0.999	0.000
H50.9 Strabismus, unspecified	0.001	0.999	0.000
M35.1 Other overlap syndromes	0.001	0.999	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.999	0.001
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.999	0.001
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations