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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs59251082
log Bayes Factor = 16.0591
Chromosome 11   position 132,584,575  (GRCh37) Explore rs59251082 on Ensembl!
Variant rs59251082 is part of Cluster X0177

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
N30-N39 Other diseases of urinary system
0.998 0.002 0.000
I20 Angina pectoris
0.992 0.008 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.991 0.009 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.991 0.009 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.990 0.010 0.000
I20.0 Unstable angina
0.986 0.014 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.984 0.016 0.000
Chapter VI Diseases of the nervous system
0.982 0.018 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.981 0.019 0.000
D60-D64 Aplastic and other anaemias
0.972 0.028 0.000
M20-M25 Other joint disorders
0.970 0.030 0.000
I30-I52 Other forms of heart disease
0.969 0.031 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.968 0.032 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.965 0.035 0.000
D64 Other anaemias
0.965 0.035 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.962 0.038 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.961 0.039 0.000
D64.9 Anaemia, unspecified
0.960 0.040 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.956 0.044 0.000
G40-G47 Episodic and paroxysmal disorders
0.955 0.045 0.000
Chapter XI Diseases of the digestive system
0.947 0.053 0.000
I84 Haemorrhoids
0.940 0.060 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.938 0.062 0.000
N81 Female genital prolapse
0.937 0.063 0.000
M25 Other joint disorders, not elsewhere classified
0.929 0.071 0.000
I84.8 Unspecified haemorrhoids with other complications
0.928 0.072 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.927 0.073 0.000
K90-K93 Other diseases of the digestive system
0.927 0.073 0.000
Chapter VII Diseases of the eye and adnexa
0.926 0.074 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.926 0.074 0.000
N30 Cystitis
0.925 0.075 0.000
O60-O75 Complications of labour and delivery
0.921 0.079 0.000
K92 Other diseases of digestive system
0.920 0.080 0.000
G43 Migraine
0.919 0.081 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.917 0.083 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.906 0.094 0.000
Chapter X Diseases of the respiratory system
0.901 0.099 0.000
I05-I09 Chronic rheumatic heart diseases
0.900 0.100 0.000
I24 Other acute ischaemic heart diseases
0.900 0.100 0.000
N81.1 Cystocele
0.897 0.103 0.000
N00-N08 Glomerular diseases
0.895 0.105 0.000
G43.9 Migraine, unspecified
0.894 0.106 0.000
N81.6 Rectocele
0.893 0.107 0.000
N39 Other disorders of urinary system
0.884 0.116 0.000
I60-I69 Cerebrovascular diseases
0.880 0.120 0.000
M05-M14 Inflammatory polyarthropathies
0.876 0.124 0.000
I21 Acute myocardial infarction
0.875 0.125 0.000
I34 Nonrheumatic mitral valve disorders
0.873 0.127 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.865 0.135 0.000
G44 Other headache syndromes
0.861 0.139 0.000
E10-E14 Diabetes mellitus
0.860 0.140 0.000
R06 Abnormalities of breathing
0.855 0.145 0.000
I45 Other conduction disorders
0.854 0.146 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.853 0.147 0.000
K70-K77 Diseases of liver
0.848 0.152 0.000
N39.3 Stress incontinence
0.847 0.153 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.845 0.155 0.000
Chapter V Mental and behavioural disorders
0.845 0.155 0.000
R06.0 Dyspnoea
0.844 0.156 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.843 0.157 0.000
M25.4 Effusion of joint
0.841 0.159 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.833 0.167 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.833 0.167 0.000
S40-S49 Injuries to the shoulder and upper arm
0.832 0.168 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.831 0.169 0.000
I25.1 Atherosclerotic heart disease
0.831 0.169 0.000
J40-J47 Chronic lower respiratory diseases
0.831 0.169 0.000
I24.8 Other forms of acute ischaemic heart disease
0.829 0.171 0.000
E20-E35 Disorders of other endocrine glands
0.829 0.171 0.000
N10-N16 Renal tubulo-interstitial diseases
0.827 0.173 0.000
I35 Nonrheumatic aortic valve disorders
0.826 0.174 0.000
M70-M79 Other soft tissue disorders
0.826 0.174 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.824 0.176 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.824 0.176 0.000
O80-O84 Delivery
0.823 0.177 0.000
E11 Non-insulin-dependent diabetes mellitus
0.821 0.179 0.000
N81.5 Vaginal enterocele
0.819 0.181 0.000
N17-N19 Renal failure
0.817 0.183 0.000
S70-S79 Injuries to the hip and thigh
0.816 0.184 0.000
I84.6 Residual haemorrhoidal skin tags
0.814 0.186 0.000
J44 Other chronic obstructive pulmonary disease
0.814 0.186 0.000
I08 Multiple valve diseases
0.811 0.189 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.811 0.189 0.000
I31 Other diseases of pericardium
0.810 0.190 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.806 0.194 0.000
H40-H42 Glaucoma
0.806 0.194 0.000
H55-H59 Other disorders of eye and adnexa
0.799 0.201 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.798 0.202 0.000
I36 Nonrheumatic tricuspid valve disorders
0.797 0.203 0.000
Chapter XX External causes of morbidity and mortality
0.796 0.204 0.000
K55-K64 Other diseases of intestines
0.789 0.211 0.000
N32 Other disorders of bladder
0.786 0.214 0.000
N60-N64 Disorders of breast
0.786 0.214 0.000
M21 Other acquired deformities of limbs
0.784 0.216 0.000
I65.2 Occlusion and stenosis of carotid artery
0.784 0.216 0.000
M35 Other systemic involvement of connective tissue
0.784 0.216 0.000
I21.9 Acute myocardial infarction, unspecified
0.782 0.218 0.000
M25.7 Osteophyte
0.780 0.220 0.000
N87 Dysplasia of cervix uteri
0.780 0.220 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.779 0.221 0.000
I84.2 Internal haemorrhoids without complication
0.778 0.222 0.000
G30-G32 Other degenerative diseases of the nervous system
0.778 0.222 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.775 0.225 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.775 0.225 0.000
N30.2 Other chronic cystitis
0.772 0.228 0.000
L60-L75 Disorders of skin appendages
0.772 0.228 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.772 0.228 0.000
M23 Internal derangement of knee
0.770 0.230 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.769 0.231 0.000
K50-K52 Noninfective enteritis and colitis
0.769 0.231 0.000
O66 Other obstructed labour
0.767 0.233 0.000
E70-E90 Metabolic disorders
0.764 0.236 0.000
I38 Endocarditis, valve unspecified
0.763 0.237 0.000
S20-S29 Injuries to the thorax
0.763 0.237 0.000
G44.2 Tension-type headache
0.759 0.241 0.000
N30.9 Cystitis, unspecified
0.759 0.241 0.000
S90-S99 Injuries to the ankle and foot
0.758 0.242 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.758 0.242 0.000
S80-S89 Injuries to the knee and lower leg
0.758 0.242 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.758 0.242 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.756 0.244 0.000
R01 Cardiac murmurs and other cardiac sounds
0.755 0.245 0.000
R00 Abnormalities of heart beat
0.755 0.245 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.755 0.245 0.000
R02 Gangrene, not elsewhere classified
0.754 0.246 0.000
N17 Acute renal failure
0.752 0.248 0.000
I45.1 Other and unspecified right bundle-branch block
0.752 0.248 0.000
I22 Subsequent myocardial infarction
0.750 0.250 0.000
M91-M94 Chondropathies
0.749 0.251 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.747 0.253 0.000
N03 Chronic nephritic syndrome
0.747 0.253 0.000
M40-M43 Deforming dorsopathies
0.746 0.254 0.000
I34.1 Mitral (valve) prolapse
0.746 0.254 0.000
I47 Paroxysmal tachycardia
0.746 0.254 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.745 0.255 0.000
I85 Oesophageal varices
0.745 0.255 0.000
G90-G99 Other disorders of the nervous system
0.745 0.255 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.743 0.257 0.000
N81.9 Female genital prolapse, unspecified
0.743 0.257 0.000
M13 Other arthritis
0.742 0.258 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.741 0.258 0.000
I20.1 Angina pectoris with documented spasm
0.741 0.259 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.741 0.259 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.740 0.260 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.740 0.260 0.000
O73 Retained placenta and membranes, without haemorrhage
0.739 0.261 0.000
I34.0 Mitral (valve) insufficiency
0.738 0.261 0.000
I33 Acute and subacute endocarditis
0.737 0.263 0.000
N30.1 Interstitial cystitis (chronic)
0.737 0.263 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.737 0.263 0.000
M65-M68 Disorders of synovium and tendon
0.735 0.265 0.000
O16 Unspecified maternal hypertension
0.735 0.265 0.000
S00-S09 Injuries to the head
0.733 0.267 0.000
I49 Other cardiac arrhythmias
0.733 0.267 0.000
M31 Other necrotising vasculopathies
0.733 0.267 0.000
M25.46 Effusion of joint (Lower leg)
0.732 0.268 0.000
N13 Obstructive and reflux uropathy
0.731 0.269 0.000
M25.9 Joint disorder, unspecified
0.730 0.270 0.000
I20.8 Other forms of angina pectoris
0.730 0.270 0.000
M24 Other specific joint derangements
0.729 0.271 0.000
I10-I15 Hypertensive diseases
0.729 0.271 0.000
N36 Other disorders of urethra
0.727 0.273 0.000
G81 Hemiplegia
0.726 0.274 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.725 0.274 0.000
N30.0 Acute cystitis
0.725 0.275 0.000
E11.9 Without complications
0.725 0.275 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.724 0.276 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.723 0.277 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.723 0.277 0.000
M06 Other rheumatoid arthritis
0.723 0.277 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.723 0.277 0.000
J30-J39 Other diseases of upper respiratory tract
0.722 0.278 0.000
K92.1 Melaena
0.722 0.278 0.000
K56.6 Other and unspecified intestinal obstruction
0.722 0.278 0.000
M25.5 Pain in joint
0.722 0.278 0.000
L20-L30 Dermatitis and eczema
0.721 0.279 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.721 0.279 0.000
R81 Glycosuria
0.720 0.280 0.000
I25.2 Old myocardial infarction
0.720 0.280 0.000
D69 Purpura and other haemorrhagic conditions
0.720 0.280 0.000
H40 Glaucoma
0.719 0.281 0.000
E78.5 Hyperlipidaemia, unspecified
0.719 0.281 0.000
N94.1 Dyspareunia
0.718 0.282 0.000
M75 Shoulder lesions
0.718 0.282 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.5 Ischaemic cardiomyopathy
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
N81.3 Complete uterovaginal prolapse
0.716 0.284 0.000
S60-S69 Injuries to the wrist and hand
0.716 0.284 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.716 0.284 0.000
N37 Urethral disorders in diseases classified elsewhere
0.716 0.284 0.000
N34 Urethritis and urethral syndrome
0.716 0.284 0.000
N33 Bladder disorders in diseases classified elsewhere
0.716 0.284 0.000
E11.3 With ophthalmic complications
0.714 0.286 0.000
R87 Abnormal findings in specimens from female genital organs
0.714 0.286 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.714 0.286 0.000
N88 Other noninflammatory disorders of cervix uteri
0.713 0.287 0.000
R80 Isolated proteinuria
0.712 0.288 0.000
Chapter XXII Codes for special purposes
0.711 0.289 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.711 0.289 0.000
D55-D59 Haemolytic anaemias
0.710 0.290 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.709 0.290 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.709 0.290 0.000
M20 Acquired deformities of fingers and toes
0.708 0.292 0.000
S50-S59 Injuries to the elbow and forearm
0.708 0.292 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.708 0.292 0.000
N99-N99 Other disorders of the genitourinary system
0.706 0.293 0.000
N17.9 Acute renal failure, unspecified
0.706 0.294 0.000
M07 Psoriatic and enteropathic arthropathies
0.706 0.294 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.706 0.294 0.000
M60-M63 Disorders of muscles
0.706 0.294 0.000
M00-M03 Infectious arthropathies
0.706 0.294 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.705 0.295 0.000
T66-T78 Other and unspecified effects of external causes
0.705 0.295 0.000
M25.47 Effusion of joint (Ankle and foot)
0.704 0.295 0.000
G70-G73 Diseases of myoneural junction and muscle
0.704 0.296 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.704 0.296 0.000
M22 Disorders of patella
0.704 0.296 0.000
H10-H13 Disorders of conjunctiva
0.704 0.296 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.703 0.296 0.000
T33-T35 Frostbite
0.703 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.703 0.296 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.703 0.296 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.703 0.296 0.000
T00-T07 Injuries involving multiple body regions
0.703 0.296 0.000
S10-S19 Injuries to the neck
0.703 0.296 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.703 0.297 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.702 0.298 0.000
D80-D89 Certain disorders involving the immune mechanism
0.702 0.298 0.000
O80 Single spontaneous delivery
0.700 0.300 0.000
N81.8 Other female genital prolapse
0.700 0.300 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.700 0.300 0.000
J90-J94 Other diseases of pleura
0.700 0.300 0.000
G44.0 Cluster headache syndrome
0.698 0.301 0.000
K92.9 Disease of digestive system, unspecified
0.698 0.302 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.697 0.303 0.000
D62 Acute posthaemorrhagic anaemia
0.697 0.303 0.000
N81.2 Incomplete uterovaginal prolapse
0.696 0.304 0.000
I05 Rheumatic mitral valve diseases
0.696 0.304 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.696 0.304 0.000
M34 Systemic sclerosis
0.696 0.304 0.000
M33 Dermatopolymyositis
0.696 0.304 0.000
M32 Systemic lupus erythematosus
0.696 0.304 0.000
M30 Polyarteritis nodosa and related conditions
0.696 0.304 0.000
N30.3 Trigonitis
0.696 0.304 0.000
I52 Other heart disorders in diseases classified elsewhere
0.695 0.305 0.000
I48 Atrial fibrillation and flutter
0.695 0.305 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.695 0.305 0.000
I41 Myocarditis in diseases classified elsewhere
0.695 0.305 0.000
I40 Acute myocarditis
0.695 0.305 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.695 0.305 0.000
I37 Pulmonary valve disorders
0.695 0.305 0.000
I32 Pericarditis in diseases classified elsewhere
0.695 0.305 0.000
I30 Acute pericarditis
0.695 0.305 0.000
I84.4 External haemorrhoids with other complications
0.695 0.305 0.000
M86-M90 Other osteopathies
0.695 0.305 0.000
O85-O92 Complications predominantly related to the puerperium
0.694 0.306 0.000
J43 Emphysema
0.693 0.306 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.693 0.307 0.000
D70 Agranulocytosis
0.693 0.307 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.692 0.308 0.000
I88 Nonspecific lymphadenitis
0.692 0.308 0.000
I87 Other disorders of veins
0.692 0.308 0.000
I86 Varicose veins of other sites
0.692 0.308 0.000
I82 Other venous embolism and thrombosis
0.692 0.308 0.000
I81 Portal vein thrombosis
0.692 0.308 0.000
D64.8 Other specified anaemias
0.692 0.308 0.000
D64.4 Congenital dyserythropoietic anaemia
0.692 0.308 0.000
D64.3 Other sideroblastic anaemias
0.692 0.308 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.692 0.308 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.692 0.308 0.000
D64.0 Hereditary sideroblastic anaemia
0.692 0.308 0.000
I50 Heart failure
0.691 0.308 0.000
O70 Perineal laceration during delivery
0.691 0.309 0.000
K74 Fibrosis and cirrhosis of liver
0.691 0.309 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.690 0.310 0.000
M80-M85 Disorders of bone density and structure
0.689 0.311 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.689 0.311 0.000
H30-H36 Disorders of choroid and retina
0.689 0.311 0.000
G40 Epilepsy
0.688 0.312 0.000
R73 Elevated blood glucose level
0.688 0.312 0.000
I83 Varicose veins of lower extremities
0.687 0.313 0.000
S40 Superficial injury of shoulder and upper arm
0.687 0.313 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.686 0.314 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.685 0.315 0.000
G41 Status epilepticus
0.685 0.315 0.000
H53-H54 Visual disturbances and blindness
0.684 0.316 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.682 0.318 0.000
G20-G26 Extrapyramidal and movement disorders
0.682 0.318 0.000
K51 Ulcerative colitis
0.681 0.319 0.000
N39.8 Other specified disorders of urinary system
0.681 0.319 0.000
I08.0 Disorders of both mitral and aortic valves
0.681 0.319 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.680 0.320 0.000
N63 Unspecified lump in breast
0.679 0.320 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.679 0.321 0.000
H57 Other disorders of eye and adnexa
0.679 0.321 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.678 0.322 0.000
N02 Recurrent and persistent haematuria
0.678 0.322 0.000
D50-D53 Nutritional anaemias
0.677 0.323 0.000
K76 Other diseases of liver
0.677 0.323 0.000
N32.0 Bladder-neck obstruction
0.677 0.323 0.000
O63 Long labour
0.676 0.324 0.000
N04 Nephrotic syndrome
0.675 0.325 0.000
I31.9 Disease of pericardium, unspecified
0.674 0.326 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.674 0.326 0.000
I84.0 Internal thrombosed haemorrhoids
0.674 0.326 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.674 0.326 0.000
R11 Nausea and vomiting
0.674 0.326 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.674 0.326 0.000
K61 Abscess of anal and rectal regions
0.673 0.327 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.673 0.327 0.000
S72 Fracture of femur
0.673 0.327 0.000
E22 Hyperfunction of pituitary gland
0.673 0.327 0.000
N98 Complications associated with artificial fertilisation
0.672 0.328 0.000
N91 Absent, scanty and rare menstruation
0.672 0.328 0.000
N82 Fistulae involving female genital tract
0.672 0.328 0.000
N96 Habitual aborter
0.672 0.328 0.000
N81.0 Female urethrocele
0.672 0.328 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.672 0.328 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.671 0.329 0.000
M75.4 Impingement syndrome of shoulder
0.669 0.331 0.000
I45.9 Conduction disorder, unspecified
0.669 0.331 0.000
M25.76 Osteophyte (Lower leg)
0.668 0.332 0.000
I84.3 External thrombosed haemorrhoids
0.668 0.332 0.000
R00.1 Bradycardia, unspecified
0.667 0.333 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.667 0.333 0.000
M25.8 Other specified joint disorders
0.666 0.334 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.666 0.334 0.000
M25.3 Other instability of joint
0.666 0.334 0.000
M25.2 Flail joint
0.666 0.334 0.000
M25.1 Fistula of joint
0.666 0.334 0.000
M25.0 Haemarthrosis
0.666 0.334 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.666 0.334 0.000
K35-K38 Diseases of appendix
0.666 0.334 0.000
G30 Alzheimer's disease
0.666 0.334 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.665 0.335 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.665 0.335 0.000
O72 Postpartum haemorrhage
0.664 0.336 0.000
E40-E46 Malnutrition
0.664 0.336 0.000
N30.4 Irradiation cystitis
0.663 0.337 0.000
Chapter VIII Diseases of the ear and mastoid process
0.662 0.338 0.000
E11.2 With renal complications
0.662 0.338 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.662 0.338 0.000
N97 Female infertility
0.662 0.338 0.000
O74 Complications of anaesthesia during labour and delivery
0.660 0.340 0.000
O71 Other obstetric trauma
0.660 0.340 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.660 0.340 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.660 0.340 0.000
O62 Abnormalities of forces of labour
0.660 0.340 0.000
O61 Failed induction of labour
0.660 0.340 0.000
O60 Preterm delivery
0.660 0.340 0.000
K92.8 Other specified diseases of digestive system
0.660 0.340 0.000
L50-L54 Urticaria and erythema
0.660 0.340 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.659 0.341 0.000
G43.8 Other migraine
0.659 0.341 0.000
G43.3 Complicated migraine
0.659 0.341 0.000
G43.2 Status migrainosus
0.659 0.341 0.000
G43.1 Migraine with aura [classical migraine]
0.659 0.341 0.000
G43.0 Migraine without aura [common migraine]
0.659 0.341 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.659 0.341 0.000
I08.8 Other multiple valve diseases
0.659 0.341 0.000
S42 Fracture of shoulder and upper arm
0.657 0.342 0.000
I12 Hypertensive renal disease
0.657 0.343 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.656 0.344 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.656 0.344 0.000
F80-F89 Disorders of psychological development
0.654 0.346 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.654 0.346 0.000
E50-E64 Other nutritional deficiencies
0.653 0.347 0.000
D75 Other diseases of blood and blood-forming organs
0.652 0.348 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.651 0.349 0.000
M21.1 Varus deformity, not elsewhere classified
0.651 0.349 0.000
K72 Hepatic failure, not elsewhere classified
0.651 0.349 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.650 0.350 0.000
E28 Ovarian dysfunction
0.650 0.350 0.000
G81.9 Hemiplegia, unspecified
0.650 0.350 0.000
S80 Superficial injury of lower leg
0.649 0.350 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.649 0.351 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.648 0.352 0.000
I27 Other pulmonary heart diseases
0.648 0.352 0.000
R04 Haemorrhage from respiratory passages
0.647 0.352 0.000
E27 Other disorders of adrenal gland
0.647 0.353 0.000
N39.4 Other specified urinary incontinence
0.647 0.353 0.000
R01.1 Cardiac murmur, unspecified
0.646 0.354 0.000
I07 Rheumatic tricuspid valve diseases
0.646 0.354 0.000
I09 Other rheumatic heart diseases
0.645 0.354 0.000
I06 Rheumatic aortic valve diseases
0.645 0.354 0.000
I24.1 Dressler's syndrome
0.645 0.355 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.645 0.355 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.645 0.355 0.000
F60-F69 Disorders of adult personality and behaviour
0.645 0.355 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.644 0.356 0.000
I42 Cardiomyopathy
0.644 0.356 0.000
N81.4 Uterovaginal prolapse, unspecified
0.643 0.357 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.643 0.357 0.000
M35.3 Polymyalgia rheumatica
0.642 0.358 0.000
J36 Peritonsillar abscess
0.642 0.358 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.642 0.358 0.000
N06 Isolated proteinuria with specified morphological lesion
0.642 0.358 0.000
N05 Unspecified nephritic syndrome
0.642 0.358 0.000
N01 Rapidly progressive nephritic syndrome
0.642 0.358 0.000
N00 Acute nephritic syndrome
0.642 0.358 0.000
K75 Other inflammatory liver diseases
0.642 0.358 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.641 0.359 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.641 0.359 0.000
W20-W49 Exposure to inanimate mechanical forces
0.641 0.359 0.000
D68 Other coagulation defects
0.640 0.360 0.000
N03.9 Unspecified
0.640 0.360 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.640 0.360 0.000
E29 Testicular dysfunction
0.639 0.361 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.638 0.362 0.000
I47.1 Supraventricular tachycardia
0.638 0.362 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.638 0.362 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.637 0.363 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.636 0.364 0.000
R47-R49 Symptoms and signs involving speech and voice
0.635 0.365 0.000
I70 Atherosclerosis
0.634 0.366 0.000
L30 Other dermatitis
0.634 0.366 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.634 0.366 0.000
N39.2 Orthostatic proteinuria, unspecified
0.634 0.366 0.000
N39.1 Persistent proteinuria, unspecified
0.634 0.366 0.000
K70 Alcoholic liver disease
0.634 0.366 0.000
I20.9 Angina pectoris, unspecified
0.633 0.367 0.000
I67 Other cerebrovascular diseases
0.633 0.367 0.000
N30.8 Other cystitis
0.633 0.367 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.631 0.369 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.631 0.369 0.000
N86 Erosion and ectropion of cervix uteri
0.631 0.369 0.000
R87.6 Abnormal cytological findings
0.631 0.369 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.630 0.370 0.000
I35.9 Aortic valve disorder, unspecified
0.629 0.370 0.000
M13.9 Arthritis, unspecified
0.630 0.370 0.000
E11.4 With neurological complications
0.629 0.371 0.000
O80.0 Spontaneous vertex delivery
0.629 0.371 0.000
J60-J70 Lung diseases due to external agents
0.629 0.371 0.000
M14 Arthropathies in other diseases classified elsewhere
0.628 0.372 0.000
M12 Other specific arthropathies
0.628 0.372 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.628 0.372 0.000
M08 Juvenile arthritis
0.628 0.372 0.000
O82 Single delivery by Caesarean section
0.628 0.372 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.627 0.373 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.627 0.373 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.627 0.373 0.000
I35.1 Aortic (valve) insufficiency
0.626 0.374 0.000
G93 Other disorders of brain
0.626 0.374 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.626 0.374 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.626 0.374 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.626 0.374 0.000
J95-J99 Other diseases of the respiratory system
0.625 0.374 0.000
S79 Other and unspecified injuries of hip and thigh
0.624 0.376 0.000
L60 Nail disorders
0.624 0.376 0.000
M06.0 Seronegative rheumatoid arthritis
0.623 0.377 0.000
M05 Seropositive rheumatoid arthritis
0.622 0.377 0.000
S29 Other and unspecified injuries of thorax
0.622 0.378 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.622 0.378 0.000
I71 Aortic aneurysm and dissection
0.621 0.379 0.000
E10 Insulin-dependent diabetes mellitus
0.621 0.379 0.000
N61 Inflammatory disorders of breast
0.621 0.379 0.000
L10-L14 Bullous disorders
0.620 0.380 0.000
N13.8 Other obstructive and reflux uropathy
0.619 0.381 0.000
M11 Other crystal arthropathies
0.619 0.381 0.000
I31.3 Pericardial effusion (noninflammatory)
0.617 0.383 0.000
H40.2 Primary angle-closure glaucoma
0.617 0.383 0.000
G44.8 Other specified headache syndromes
0.617 0.383 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.617 0.383 0.000
G44.3 Chronic posttraumatic headache
0.617 0.383 0.000
G44.1 Vascular headache, not elsewhere classified
0.617 0.383 0.000
E13 Other specified diabetes mellitus
0.616 0.384 0.000
E12 Malnutrition-related diabetes mellitus
0.616 0.384 0.000
I73 Other peripheral vascular diseases
0.616 0.384 0.000
K56.4 Other impaction of intestine
0.615 0.385 0.000
N75 Diseases of Bartholin's gland
0.615 0.385 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.614 0.386 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.614 0.386 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.614 0.386 0.000
R06.7 Sneezing
0.613 0.387 0.000
R06.6 Hiccough
0.613 0.387 0.000
R06.3 Periodic breathing
0.613 0.387 0.000
R06.1 Stridor
0.613 0.387 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.613 0.387 0.000
I45.8 Other specified conduction disorders
0.613 0.387 0.000
I45.5 Other specified heart block
0.613 0.387 0.000
I45.4 Nonspecific intraventricular block
0.613 0.387 0.000
I45.3 Trifascicular block
0.613 0.387 0.000
I45.2 Bifascicular block
0.613 0.387 0.000
I45.0 Right fascicular block
0.613 0.387 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.612 0.388 0.000
R82 Other abnormal findings in urine
0.612 0.388 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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