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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs599839
log Bayes Factor = 117.967
Chromosome 1   position 109,822,166  (GRCh37) Explore rs599839 on Ensembl!
Variant rs599839 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.5 Hyperlipidaemia, unspecified
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.000 1.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.002 0.998
Z95.0 Presence of cardiac pacemaker
0.000 0.011 0.989
I21.4 Acute subendocardial myocardial infarction
0.000 0.033 0.967
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.038 0.962
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.074 0.926
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.096 0.904
E78.8 Other disorders of lipoprotein metabolism
0.000 0.097 0.903
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.099 0.901
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.100 0.900
I71 Aortic aneurysm and dissection
0.000 0.103 0.897
Chapter IX Diseases of the circulatory system
0.000 0.105 0.895
I73 Other peripheral vascular diseases
0.000 0.112 0.888
I73.9 Peripheral vascular disease, unspecified
0.000 0.113 0.887
I30-I52 Other forms of heart disease
0.000 0.145 0.855
I50 Heart failure
0.000 0.148 0.852
I25.3 Aneurysm of heart
0.000 0.156 0.844
I35 Nonrheumatic aortic valve disorders
0.000 0.167 0.833
I35.0 Aortic (valve) stenosis
0.000 0.169 0.831
I45 Other conduction disorders
0.000 0.179 0.821
I50.1 Left ventricular failure
0.000 0.179 0.821
I45.1 Other and unspecified right bundle-branch block
0.000 0.181 0.819
I22 Subsequent myocardial infarction
0.000 0.202 0.798
E78.4 Other hyperlipidaemia
0.000 0.207 0.793
I50.0 Congestive heart failure
0.000 0.213 0.787
E78.6 Lipoprotein deficiency
0.000 0.217 0.783
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.221 0.779
I25.4 Coronary artery aneurysm
0.000 0.229 0.770
I50.9 Heart failure, unspecified
0.000 0.239 0.761
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.245 0.755
I24 Other acute ischaemic heart diseases
0.000 0.245 0.755
I74 Arterial embolism and thrombosis
0.000 0.249 0.751
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.251 0.749
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.259 0.741
E78.2 Mixed hyperlipidaemia
0.000 0.275 0.725
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.285 0.715
I46 Cardiac arrest
0.000 0.287 0.713
E78.1 Pure hyperglyceridaemia
0.000 0.296 0.704
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.310 0.690
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.328 0.672
I45.2 Bifascicular block
0.000 0.329 0.671
I70 Atherosclerosis
0.000 0.331 0.669
I35.8 Other aortic valve disorders
0.000 0.340 0.660
I25.5 Ischaemic cardiomyopathy
0.000 0.342 0.658
I20.8 Other forms of angina pectoris
0.000 0.344 0.656
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.344 0.656
I46.0 Cardiac arrest with successful resuscitation
0.000 0.351 0.649
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.356 0.643
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.356 0.643
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.356 0.643
I00-I02 Acute rheumatic fever
0.000 0.360 0.640
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.369 0.631
I42 Cardiomyopathy
0.000 0.372 0.628
I40 Acute myocarditis
0.000 0.375 0.625
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.377 0.623
I24.8 Other forms of acute ischaemic heart disease
0.000 0.379 0.621
I33 Acute and subacute endocarditis
0.000 0.387 0.613
I52 Other heart disorders in diseases classified elsewhere
0.000 0.387 0.613
I48 Atrial fibrillation and flutter
0.000 0.387 0.613
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.387 0.613
I41 Myocarditis in diseases classified elsewhere
0.000 0.387 0.613
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.387 0.613
I32 Pericarditis in diseases classified elsewhere
0.000 0.387 0.613
I73.8 Other specified peripheral vascular diseases
0.000 0.389 0.611
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.390 0.610
I34 Nonrheumatic mitral valve disorders
0.000 0.397 0.603
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.404 0.596
I74.8 Embolism and thrombosis of other arteries
0.000 0.408 0.592
I22.8 Subsequent myocardial infarction of other sites
0.000 0.410 0.590
I45.5 Other specified heart block
0.000 0.411 0.589
I45.0 Right fascicular block
0.000 0.411 0.589
I72 Other aneurysm
0.000 0.412 0.588
I71.0 Dissection of aorta [any part]
0.000 0.421 0.579
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.426 0.574
Z95.2 Presence of prosthetic heart valve
0.000 0.428 0.572
I20.1 Angina pectoris with documented spasm
0.000 0.436 0.564
I45.3 Trifascicular block
0.000 0.439 0.561
I34.1 Mitral (valve) prolapse
0.000 0.439 0.561
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.441 0.559
I79.1 Aortitis in diseases classified elsewhere
0.000 0.441 0.559
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.441 0.559
I42.8 Other cardiomyopathies
0.000 0.446 0.554
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.456 0.543
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.460 0.540
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.461 0.539
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.464 0.536
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.464 0.535
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.472 0.528
I77 Other disorders of arteries and arterioles
0.000 0.474 0.526
I38 Endocarditis, valve unspecified
0.000 0.477 0.523
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.479 0.521
I72.4 Aneurysm of artery of lower extremity
0.000 0.485 0.515
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.487 0.512
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.487 0.512
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.487 0.512
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.487 0.512
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.487 0.512
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.487 0.512
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.487 0.512
I46.1 Sudden cardiac death, so described
0.000 0.489 0.511
I23.8 Other current complications following acute myocardial infarction
0.000 0.489 0.510
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.502 0.498
I42.2 Other hypertrophic cardiomyopathy
0.000 0.502 0.498
I35.9 Aortic valve disorder, unspecified
0.000 0.506 0.494
I70.1 Atherosclerosis of renal artery
0.000 0.508 0.492
I45.9 Conduction disorder, unspecified
0.000 0.512 0.488
I37 Pulmonary valve disorders
0.000 0.516 0.484
I70.9 Generalised and unspecified atherosclerosis
0.000 0.520 0.480
I33.0 Acute and subacute infective endocarditis
0.000 0.521 0.479
I70.8 Atherosclerosis of other arteries
0.000 0.529 0.471
I24.1 Dressler's syndrome
0.000 0.535 0.465
I21.3 Acute transmural myocardial infarction of unspecified site
0.001 0.535 0.464
I78 Diseases of capillaries
0.000 0.536 0.464
I72.3 Aneurysm of iliac artery
0.000 0.536 0.464
I40.0 Infective myocarditis
0.000 0.540 0.460
I02 Rheumatic chorea
0.000 0.541 0.459
I01 Rheumatic fever with heart involvement
0.000 0.541 0.459
I00 Rheumatic fever without mention of heart involvement
0.000 0.543 0.457
I30 Acute pericarditis
0.000 0.543 0.457
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.549 0.450
I42.5 Other restrictive cardiomyopathy
0.000 0.549 0.450
I42.4 Endocardial fibroelastosis
0.000 0.549 0.450
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.549 0.450
I40.9 Acute myocarditis, unspecified
0.000 0.552 0.448
I40.8 Other acute myocarditis
0.000 0.552 0.448
I40.1 Isolated myocarditis
0.000 0.552 0.448
I10-I15 Hypertensive diseases
0.000 0.552 0.448
I36 Nonrheumatic tricuspid valve disorders
0.001 0.554 0.446
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.560 0.439
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.560 0.439
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.560 0.439
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.560 0.439
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.560 0.439
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.560 0.439
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.560 0.439
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.560 0.439
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.560 0.439
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.560 0.439
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.560 0.439
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.560 0.439
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.560 0.439
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.560 0.439
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.560 0.439
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.560 0.439
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.560 0.439
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.560 0.439
I48.4 Atypical atrial flutter
0.000 0.560 0.439
I48.3 Typical atrial flutter
0.000 0.560 0.439
I48.2 Chronic atrial fibrillation
0.000 0.560 0.439
I48.1 Persistent atrial fibrillation
0.000 0.560 0.439
I48.0 Paroxysmal atrial fibrillation
0.000 0.560 0.439
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.560 0.439
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.560 0.439
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.560 0.439
I70.0 Atherosclerosis of aorta
0.000 0.561 0.439
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.562 0.438
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.568 0.432
I42.6 Alcoholic cardiomyopathy
0.000 0.570 0.430
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.574 0.426
I45.8 Other specified conduction disorders
0.000 0.574 0.425
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.578 0.422
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.578 0.422
I42.9 Cardiomyopathy, unspecified
0.000 0.580 0.419
I45.4 Nonspecific intraventricular block
0.000 0.584 0.416
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.590 0.409
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.594 0.406
I72.2 Aneurysm of renal artery
0.000 0.595 0.404
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.596 0.404
I34.0 Mitral (valve) insufficiency
0.000 0.607 0.393
I46.9 Cardiac arrest, unspecified
0.000 0.608 0.392
I77.6 Arteritis, unspecified
0.000 0.609 0.391
I33.9 Acute endocarditis, unspecified
0.000 0.610 0.389
O34.2 Maternal care due to uterine scar from previous surgery
0.383 0.617 0.000
I15 Secondary hypertension
0.000 0.619 0.381
I72.8 Aneurysm of other specified arteries
0.000 0.621 0.379
I77.1 Stricture of artery
0.000 0.621 0.379
I77.5 Necrosis of artery
0.000 0.623 0.377
I77.4 Coeliac artery compression syndrome
0.000 0.623 0.377
I77.3 Arterial fibromuscular dysplasia
0.000 0.623 0.377
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.626 0.374
I45.6 Preexcitation syndrome
0.000 0.626 0.374
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.627 0.373
I77.2 Rupture of artery
0.000 0.627 0.373
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.628 0.372
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.634 0.365
I77.8 Other specified disorders of arteries and arterioles
0.000 0.637 0.363
I11 Hypertensive heart disease
0.000 0.637 0.363
I72.9 Aneurysm of unspecified site
0.000 0.646 0.354
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.647 0.353
I72.1 Aneurysm of artery of upper extremity
0.000 0.648 0.351
I37.9 Pulmonary valve disorder, unspecified
0.000 0.653 0.347
I37.8 Other pulmonary valve disorders
0.000 0.653 0.347
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.653 0.347
I37.0 Pulmonary valve stenosis
0.000 0.653 0.347
S00.8 Superficial injury of other parts of head
0.000 0.653 0.347
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.655 0.345
I49 Other cardiac arrhythmias
0.000 0.655 0.345
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.655 0.344
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.656 0.344
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.656 0.344
I28 Other diseases of pulmonary vessels
0.001 0.659 0.340
Z82.2 Family history of deafness and hearing loss
0.000 0.661 0.339
I72.0 Aneurysm of carotid artery
0.000 0.661 0.338
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.662 0.338
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.667 0.333
I78.9 Disease of capillaries, unspecified
0.000 0.667 0.333
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.667 0.333
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.671 0.329
I01.8 Other acute rheumatic heart disease
0.000 0.671 0.329
I01.2 Acute rheumatic myocarditis
0.000 0.671 0.329
I01.1 Acute rheumatic endocarditis
0.000 0.671 0.329
I01.0 Acute rheumatic pericarditis
0.000 0.671 0.329
I02.9 Rheumatic chorea without heart involvement
0.000 0.671 0.329
I02.0 Rheumatic chorea with heart involvement
0.000 0.671 0.329
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.671 0.329
I30.8 Other forms of acute pericarditis
0.000 0.672 0.328
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.672 0.328
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.673 0.327
I77.0 Arteriovenous fistula, acquired
0.000 0.675 0.325
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.677 0.323
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.679 0.321
I13 Hypertensive heart and renal disease
0.000 0.679 0.321
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.001 0.680 0.320
I36.8 Other nonrheumatic tricuspid valve disorders
0.001 0.680 0.320
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.001 0.680 0.320
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.001 0.680 0.320
I49.5 Sick sinus syndrome
0.000 0.680 0.320
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.681 0.319
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.685 0.315
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.686 0.314
I78.8 Other diseases of capillaries
0.000 0.686 0.314
I15.9 Seconday hypertension, unspecified
0.000 0.688 0.312
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.690 0.310
S00 Superficial injury of head
0.000 0.690 0.310
I74.5 Embolism and thrombosis of iliac artery
0.000 0.691 0.308
I15.1 Hypertension secondary to other renal disorders
0.000 0.693 0.307
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.700 0.300
I28.8 Other specified diseases of pulmonary vessels
0.000 0.709 0.291
S00.0 Superficial injury of scalp
0.000 0.710 0.289
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.713 0.287
Z95.3 Presence of xenogenic heart valve
0.001 0.715 0.284
Z82.1 Family history of blindness and visual loss
0.000 0.715 0.285
I49.1 Atrial premature depolarisation
0.000 0.719 0.281
I49.8 Other specified cardiac arrhythmias
0.000 0.723 0.277
I30.1 Infective pericarditis
0.000 0.723 0.277
S00.7 Multiple superficial injuries of head
0.000 0.723 0.276
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.726 0.274
I15.8 Other secondary hypertension
0.000 0.726 0.273
I15.2 Hypertension secondary to endocrine disorders
0.000 0.726 0.273
I15.0 Renovascular hypertension
0.000 0.726 0.273
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.737 0.263
I51 Complications and ill-defined descriptions of heart disease
0.000 0.738 0.262
I73.0 Raynaud's syndrome
0.000 0.739 0.261
I42.0 Dilated cardiomyopathy
0.000 0.740 0.260
I05-I09 Chronic rheumatic heart diseases
0.000 0.744 0.256
I30.9 Acute pericarditis, unspecified
0.000 0.748 0.252
I49.2 Junctional premature depolarisation
0.000 0.752 0.247
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.756 0.244
I28.1 Aneurysm of pulmonary artery
0.001 0.756 0.244
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.756 0.244
I99 Other and unspecified disorders of circulatory system
0.000 0.759 0.241
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.770 0.230
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.770 0.230
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.770 0.230
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.770 0.230
S00.3 Superficial injury of nose
0.000 0.771 0.229
S00.5 Superficial injury of lip and oral cavity
0.000 0.774 0.226
O34 Maternal care for known or suspected abnormality of pelvic organs
0.225 0.775 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.779 0.221
I37.1 Pulmonary valve insufficiency
0.001 0.782 0.217
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.787 0.213
I49.4 Other and unspecified premature depolarisation
0.000 0.787 0.213
S00.9 Superficial injury of head, part unspecified
0.000 0.791 0.209
I51.0 Cardiac septal defect, acquired
0.000 0.792 0.208
S00.1 Contusion of eyelid and periocular area
0.000 0.793 0.207
I51.8 Other ill-defined heart diseases
0.000 0.800 0.200
I51.9 Heart disease, unspecified
0.000 0.807 0.193
S00.4 Superficial injury of ear
0.000 0.807 0.193
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.808 0.192
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.812 0.188
I78.1 Naevus, nonneoplastic
0.000 0.813 0.187
O34.0 Maternal care for congenital malformation of uterus
0.184 0.815 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.181 0.819 0.000
I06 Rheumatic aortic valve diseases
0.000 0.821 0.179
O34.8 Maternal care for other abnormalities of pelvic organs
0.179 0.821 0.000
I09 Other rheumatic heart diseases
0.000 0.822 0.178
I97.1 Other functional disturbances following cardiac surgery
0.000 0.823 0.177
I31 Other diseases of pericardium
0.000 0.828 0.172
I51.6 Cardiovascular disease, unspecified
0.000 0.836 0.164
Z82.3 Family history of stroke
0.000 0.838 0.162
O34.6 Maternal care for abnormality of vagina
0.162 0.838 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.162 0.838 0.000
I07 Rheumatic tricuspid valve diseases
0.000 0.839 0.161
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.839 0.160
O34.7 Maternal care for abnormality of vulva and perineum
0.159 0.841 0.000
I26 Pulmonary embolism
0.005 0.844 0.150
O34.3 Maternal care for cervical incompetence
0.155 0.844 0.000
O34.1 Maternal care for tumour of corpus uteri
0.154 0.845 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.001 0.846 0.153
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.847 0.153
I97.0 Postcardiotomy syndrome
0.000 0.847 0.153
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.848 0.152
O34.4 Maternal care for other abnormalities of cervix
0.150 0.850 0.000
I51.7 Cardiomegaly
0.000 0.852 0.148
I27 Other pulmonary heart diseases
0.000 0.854 0.146
I51.5 Myocardial degeneration
0.000 0.854 0.146
I12 Hypertensive renal disease
0.000 0.857 0.143
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.865 0.135
I05 Rheumatic mitral valve diseases
0.000 0.867 0.133
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.871 0.128
I06.8 Other rheumatic aortic valve diseases
0.000 0.871 0.128
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.871 0.128
I06.0 Rheumatic aortic stenosis
0.000 0.871 0.128
I09.8 Other specified rheumatic heart diseases
0.000 0.872 0.128
I09.2 Chronic rheumatic pericarditis
0.000 0.872 0.128
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.872 0.128
I09.0 Rheumatic myocarditis
0.000 0.872 0.128
I06.1 Rheumatic aortic insufficiency
0.000 0.876 0.124
I31.8 Other specified diseases of pericardium
0.000 0.877 0.123
I31.2 Haemopericardium, not elsewhere classified
0.000 0.877 0.123
S00-S09 Injuries to the head
0.000 0.878 0.122
I09.9 Rheumatic heart disease, unspecified
0.000 0.878 0.122
I35.1 Aortic (valve) insufficiency
0.000 0.882 0.118
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.884 0.116
I07.9 Tricuspid valve disease, unspecified
0.000 0.884 0.115
I07.8 Other tricuspid valve diseases
0.000 0.884 0.115
I07.2 Tricuspid stenosis with insufficiency
0.000 0.884 0.115
I07.0 Tricuspid stenosis
0.000 0.884 0.115
I27.8 Other specified pulmonary heart diseases
0.000 0.888 0.111
I95 Hypotension
0.000 0.889 0.111
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.891 0.109
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.891 0.109
I98.0 Cardiovascular syphilis
0.000 0.891 0.109
I05.2 Mitral stenosis with insufficiency
0.000 0.891 0.108
S01 Open wound of head
0.000 0.892 0.108
S01.9 Open wound of head, part unspecified
0.000 0.894 0.106
I31.0 Chronic adhesive pericarditis
0.000 0.894 0.105
I27.1 Kyphoscoliotic heart disease
0.000 0.895 0.105
I27.9 Pulmonary heart disease, unspecified
0.000 0.895 0.105
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.896 0.103
I49.0 Ventricular fibrillation and flutter
0.000 0.897 0.103
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.004 0.898 0.098
I31.1 Chronic constrictive pericarditis
0.000 0.902 0.097
S01.7 Multiple open wounds of head
0.000 0.902 0.098
I05.8 Other mitral valve diseases
0.000 0.904 0.095
I07.1 Tricuspid insufficiency
0.000 0.907 0.093
S09 Other and unspecified injuries of head
0.000 0.911 0.089
Z95.4 Presence of other heart-valve replacement
0.000 0.911 0.088
S02 Fracture of skull and facial bones
0.000 0.912 0.088
S08 Traumatic amputation of part of head
0.000 0.912 0.088
S07 Crushing injury of head
0.000 0.912 0.088
S04 Injury of cranial nerves
0.000 0.912 0.088
I05.1 Rheumatic mitral insufficiency
0.000 0.913 0.087
I05.0 Mitral stenosis
0.000 0.913 0.087
S01.1 Open wound of eyelid and periocular area
0.000 0.913 0.087
S05 Injury of eye and orbit
0.000 0.913 0.087
I51.4 Myocarditis, unspecified
0.001 0.914 0.085
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.914 0.086
I95.1 Orthostatic hypotension
0.000 0.914 0.086
I47 Paroxysmal tachycardia
0.000 0.915 0.084
S01.3 Open wound of ear
0.000 0.916 0.084
S01.2 Open wound of nose
0.000 0.920 0.080
S02.2 Fracture of nasal bones
0.000 0.921 0.079
S02.0 Fracture of vault of skull
0.000 0.921 0.079
I12.9 Hypertensive renal disease without renal failure
0.000 0.923 0.077
I08 Multiple valve diseases
0.000 0.924 0.076
S09.8 Other specified injuries of head
0.000 0.924 0.076
S02.20 Fracture of nasal bones (closed)
0.000 0.927 0.073
S02.00 Fracture of vault of skull (closed)
0.000 0.927 0.073
S05.8 Other injuries of eye and orbit
0.000 0.929 0.071
I10 Essential (primary) hypertension
0.000 0.929 0.071
S01.4 Open wound of cheek and temporomandibular area
0.000 0.930 0.069
I95.9 Hypotension, unspecified
0.000 0.931 0.069
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.932 0.068
S03.2 Dislocation of tooth
0.000 0.932 0.068
I31.3 Pericardial effusion (noninflammatory)
0.000 0.934 0.066
S02.7 Multiple fractures involving skull and facial bones
0.000 0.934 0.066
S05.1 Contusion of eyeball and orbital tissues
0.000 0.935 0.065
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.936 0.064
I31.9 Disease of pericardium, unspecified
0.000 0.936 0.064
S09.7 Multiple injuries of head
0.000 0.936 0.064
S09.2 Traumatic rupture of ear drum
0.000 0.936 0.064
S09.1 Injury of muscle and tendon of head
0.000 0.936 0.064
S04.9 Injury of unspecified cranial nerve
0.000 0.937 0.063
S04.8 Injury of other cranial nerves
0.000 0.937 0.063
S04.7 Injury of accessory nerve
0.000 0.937 0.063
S04.6 Injury of acoustic nerve
0.000 0.937 0.063
S04.5 Injury of facial nerve
0.000 0.937 0.063
S04.4 Injury of abducent nerve
0.000 0.937 0.063
S04.3 Injury of trigeminal nerve
0.000 0.937 0.063
S04.2 Injury of trochlear nerve
0.000 0.937 0.063
S04.1 Injury of oculomotor nerve
0.000 0.937 0.063
S04.0 Injury of optic nerve and pathways
0.000 0.937 0.063
S07.9 Crushing injury of head, part unspecified
0.000 0.937 0.063
S07.8 Crushing injury of other parts of head
0.000 0.937 0.063
S07.1 Crushing injury of skull
0.000 0.937 0.063
S07.0 Crushing injury of face
0.000 0.937 0.063
S08.9 Traumatic amputation of unspecified part of head
0.000 0.937 0.063
S08.8 Traumatic amputation of other parts of head
0.000 0.937 0.063
S08.1 Traumatic amputation of ear
0.000 0.937 0.063
S08.0 Avulsion of scalp
0.000 0.937 0.063
I95.8 Other hypotension
0.000 0.937 0.063
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.937 0.063
K05.3 Chronic periodontitis
0.063 0.937 0.000
S05.7 Avulsion of eye
0.000 0.938 0.062
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.938 0.062
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.938 0.062
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.938 0.062
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.938 0.062
S02.8 Fractures of other skull and facial bones
0.000 0.938 0.062
I27.0 Primary pulmonary hypertension
0.000 0.938 0.062
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head
0.000 0.938 0.062
S03.4 Sprain and strain of jaw
0.000 0.938 0.062
S03.3 Dislocation of other and unspecified parts of head
0.000 0.938 0.062
S03.0 Dislocation of jaw
0.000 0.938 0.062
I95.0 Idiopathic hypotension
0.000 0.939 0.061
S05.9 Injury of eye and orbit, part unspecified
0.000 0.940 0.060
S09.0 Injury of blood vessels of head, not elsewhere classified
0.000 0.940 0.060
S02.21 Fracture of nasal bones (open)
0.000 0.943 0.057
S02.01 Fracture of vault of skull (open)
0.000 0.943 0.057
I49.3 Ventricular premature depolarisation
0.000 0.943 0.056
S01.5 Open wound of lip and oral cavity
0.000 0.944 0.056
S02.6 Fracture of mandible
0.000 0.945 0.055
S02.3 Fracture of orbital floor
0.000 0.946 0.054
I95.2 Hypotension due to drugs
0.000 0.946 0.053
S03.1 Dislocation of septal cartilage of nose
0.000 0.949 0.051
S02.4 Fracture of malar and maxillary bones
0.000 0.950 0.050
I08.9 Multiple valve disease, unspecified
0.000 0.950 0.050
I47.0 Reentry ventricular arrhythmia
0.000 0.950 0.050
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.950 0.050
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.950 0.050
S09.9 Unspecified injury of head
0.000 0.950 0.050
S02.5 Fracture of tooth
0.000 0.952 0.048
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.952 0.047
I08.8 Other multiple valve diseases
0.000 0.953 0.047
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.953 0.047
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.954 0.046
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.955 0.045
I05.9 Mitral valve disease, unspecified
0.001 0.955 0.044
S02.81 Fractures of other skull and facial bones (open)
0.000 0.955 0.045
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.955 0.044
S02.1 Fracture of base of skull
0.000 0.956 0.044
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.956 0.044
K05 Gingivitis and periodontal diseases
0.041 0.959 0.000
S02.61 Fracture of mandible (open)
0.000 0.961 0.039
S02.31 Fracture of orbital floor (open)
0.000 0.961 0.039
S06 Intracranial injury
0.000 0.962 0.038
I27.2 Other secondary pulmonary hypertension
0.001 0.963 0.037
K05.6 Periodontal disease, unspecified
0.037 0.963 0.000
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.964 0.036
I49.9 Cardiac arrhythmia, unspecified
0.000 0.964 0.036
I47.2 Ventricular tachycardia
0.000 0.965 0.035
S02.51 Fracture of tooth (open)
0.000 0.965 0.034
S06.3 Focal brain injury
0.000 0.967 0.033
K05.1 Chronic gingivitis
0.033 0.967 0.000
J38.7 Other diseases of larynx
0.031 0.969 0.000
S02.60 Fracture of mandible (closed)
0.000 0.969 0.031
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.970 0.030
S02.30 Fracture of orbital floor (closed)
0.000 0.970 0.030
K05.2 Acute periodontitis
0.030 0.970 0.000
K05.4 Periodontosis
0.030 0.970 0.000
K05.0 Acute gingivitis
0.030 0.970 0.000
S02.11 Fracture of base of skull (open)
0.000 0.972 0.027
S06.7 Intracranial injury with prolonged coma
0.000 0.972 0.027
S06.1 Traumatic cerebral oedema
0.000 0.972 0.027
K05.5 Other periodontal diseases
0.027 0.973 0.000
J38.2 Nodules of vocal cords
0.027 0.973 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.026 0.974 0.000
S06.4 Epidural haemorrhage
0.000 0.974 0.026
S06.9 Intracranial injury, unspecified
0.000 0.975 0.025
S06.31 Focal brain injury (with open intracranial wound)
0.000 0.976 0.024
J38.6 Stenosis of larynx
0.023 0.976 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.977 0.023
S06.2 Diffuse brain injury
0.000 0.977 0.023
I47.9 Paroxysmal tachycardia, unspecified
0.001 0.977 0.022
S06.6 Traumatic subarachnoid haemorrhage
0.000 0.978 0.022
K05.22 Aggressive periodontitis, generalized
0.021 0.978 0.000
S06.8 Other intracranial injuries
0.000 0.978 0.021
S06.0 Concussion
0.000 0.979 0.021
S02.10 Fracture of base of skull (closed)
0.000 0.979 0.021
J38.0 Paralysis of vocal cords and larynx
0.021 0.979 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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