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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs602633
log Bayes Factor = 124.913
Chromosome 1   position 109,821,511  (GRCh37) Explore rs602633 on Ensembl!
Variant rs602633 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.5 Hyperlipidaemia, unspecified
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.000 1.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.001 0.999
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.002 0.998
Chapter IX Diseases of the circulatory system
0.000 0.003 0.997
I30-I52 Other forms of heart disease
0.000 0.005 0.995
I71 Aortic aneurysm and dissection
0.000 0.006 0.994
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.006 0.994
I50 Heart failure
0.000 0.009 0.991
I35 Nonrheumatic aortic valve disorders
0.000 0.012 0.988
I35.0 Aortic (valve) stenosis
0.000 0.012 0.988
I73 Other peripheral vascular diseases
0.000 0.013 0.987
I73.9 Peripheral vascular disease, unspecified
0.000 0.014 0.986
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.021 0.979
I50.1 Left ventricular failure
0.000 0.027 0.973
I21.4 Acute subendocardial myocardial infarction
0.000 0.039 0.961
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.043 0.957
Z95.0 Presence of cardiac pacemaker
0.000 0.050 0.950
I45 Other conduction disorders
0.000 0.052 0.948
I45.1 Other and unspecified right bundle-branch block
0.000 0.063 0.937
I50.0 Congestive heart failure
0.000 0.065 0.935
I46 Cardiac arrest
0.000 0.075 0.925
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.091 0.909
I46.0 Cardiac arrest with successful resuscitation
0.000 0.118 0.882
I20.8 Other forms of angina pectoris
0.000 0.119 0.881
I74 Arterial embolism and thrombosis
0.000 0.128 0.872
I25.3 Aneurysm of heart
0.000 0.132 0.868
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.135 0.865
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.137 0.863
E78.8 Other disorders of lipoprotein metabolism
0.000 0.138 0.862
I22 Subsequent myocardial infarction
0.000 0.146 0.854
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.193 0.807
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.214 0.786
I50.9 Heart failure, unspecified
0.000 0.223 0.777
E78.4 Other hyperlipidaemia
0.000 0.225 0.775
I25.4 Coronary artery aneurysm
0.000 0.225 0.775
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.234 0.766
E78.2 Mixed hyperlipidaemia
0.000 0.235 0.765
I35.8 Other aortic valve disorders
0.000 0.237 0.763
I45.2 Bifascicular block
0.000 0.243 0.757
I24 Other acute ischaemic heart diseases
0.000 0.248 0.752
I42 Cardiomyopathy
0.000 0.259 0.741
I40 Acute myocarditis
0.000 0.261 0.739
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.261 0.738
I45.5 Other specified heart block
0.000 0.280 0.720
I23 Certain current complications following acute myocardial infarction
0.000 0.282 0.718
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
I52 Other heart disorders in diseases classified elsewhere
0.000 0.287 0.713
I48 Atrial fibrillation and flutter
0.000 0.287 0.713
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.287 0.713
I41 Myocarditis in diseases classified elsewhere
0.000 0.287 0.713
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.287 0.713
I32 Pericarditis in diseases classified elsewhere
0.000 0.287 0.713
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.287 0.713
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.287 0.713
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.287 0.713
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.287 0.713
I74.8 Embolism and thrombosis of other arteries
0.000 0.294 0.706
I00-I02 Acute rheumatic fever
0.000 0.295 0.705
I33 Acute and subacute endocarditis
0.000 0.309 0.691
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.314 0.686
I35.9 Aortic valve disorder, unspecified
0.000 0.318 0.682
I45.0 Right fascicular block
0.000 0.320 0.680
I34 Nonrheumatic mitral valve disorders
0.000 0.325 0.675
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.329 0.671
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.329 0.671
I72 Other aneurysm
0.000 0.331 0.669
E78.1 Pure hyperglyceridaemia
0.000 0.334 0.666
I46.1 Sudden cardiac death, so described
0.000 0.337 0.663
I45.3 Trifascicular block
0.000 0.341 0.659
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.341 0.659
I24.8 Other forms of acute ischaemic heart disease
0.000 0.347 0.653
I70 Atherosclerosis
0.000 0.349 0.651
I73.8 Other specified peripheral vascular diseases
0.000 0.350 0.650
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.366 0.633
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.372 0.628
I42.8 Other cardiomyopathies
0.000 0.373 0.627
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.375 0.625
I45.9 Conduction disorder, unspecified
0.000 0.376 0.624
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.379 0.621
I34.1 Mitral (valve) prolapse
0.000 0.380 0.620
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.381 0.619
I79.1 Aortitis in diseases classified elsewhere
0.000 0.381 0.619
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.381 0.619
I46.9 Cardiac arrest, unspecified
0.000 0.381 0.619
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.383 0.617
I42.2 Other hypertrophic cardiomyopathy
0.000 0.383 0.617
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.388 0.612
Z95.2 Presence of prosthetic heart valve
0.000 0.400 0.600
I38 Endocarditis, valve unspecified
0.000 0.408 0.592
I22.8 Subsequent myocardial infarction of other sites
0.000 0.411 0.589
I71.0 Dissection of aorta [any part]
0.000 0.412 0.587
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.420 0.580
I25.5 Ischaemic cardiomyopathy
0.000 0.421 0.579
I20.1 Angina pectoris with documented spasm
0.000 0.426 0.574
I72.3 Aneurysm of iliac artery
0.000 0.437 0.563
I72.4 Aneurysm of artery of lower extremity
0.000 0.440 0.560
I40.0 Infective myocarditis
0.000 0.443 0.556
I45.8 Other specified conduction disorders
0.000 0.445 0.555
I37 Pulmonary valve disorders
0.000 0.447 0.552
I30 Acute pericarditis
0.000 0.452 0.548
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.452 0.547
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.456 0.544
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.469 0.531
I42.5 Other restrictive cardiomyopathy
0.000 0.469 0.531
I42.4 Endocardial fibroelastosis
0.000 0.469 0.531
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.469 0.531
I40.9 Acute myocarditis, unspecified
0.000 0.470 0.530
I40.8 Other acute myocarditis
0.000 0.470 0.530
I40.1 Isolated myocarditis
0.000 0.470 0.530
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.470 0.530
I33.0 Acute and subacute infective endocarditis
0.000 0.472 0.528
I45.6 Preexcitation syndrome
0.000 0.473 0.527
I36 Nonrheumatic tricuspid valve disorders
0.001 0.483 0.517
I10-I15 Hypertensive diseases
0.000 0.483 0.517
I23.8 Other current complications following acute myocardial infarction
0.000 0.484 0.515
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.485 0.515
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.485 0.515
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.485 0.515
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.485 0.515
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.485 0.515
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.485 0.515
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.485 0.515
I42.6 Alcoholic cardiomyopathy
0.000 0.487 0.513
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.489 0.511
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.489 0.511
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.489 0.511
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.489 0.511
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.489 0.511
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.489 0.511
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.489 0.511
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.489 0.511
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.489 0.511
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.489 0.511
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.489 0.511
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.489 0.511
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.489 0.511
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.489 0.511
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.489 0.511
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.489 0.511
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.489 0.511
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.489 0.511
I48.4 Atypical atrial flutter
0.000 0.489 0.511
I48.3 Typical atrial flutter
0.000 0.489 0.511
I48.2 Chronic atrial fibrillation
0.000 0.489 0.511
I48.1 Persistent atrial fibrillation
0.000 0.489 0.511
I48.0 Paroxysmal atrial fibrillation
0.000 0.489 0.511
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.489 0.511
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.489 0.511
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.489 0.511
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.492 0.508
I02 Rheumatic chorea
0.000 0.494 0.505
I01 Rheumatic fever with heart involvement
0.000 0.494 0.505
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.495 0.505
I45.4 Nonspecific intraventricular block
0.000 0.503 0.497
I00 Rheumatic fever without mention of heart involvement
0.000 0.504 0.495
I42.9 Cardiomyopathy, unspecified
0.000 0.507 0.493
I77 Other disorders of arteries and arterioles
0.000 0.514 0.486
I49 Other cardiac arrhythmias
0.000 0.520 0.480
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.520 0.480
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.520 0.480
I72.8 Aneurysm of other specified arteries
0.000 0.521 0.479
I70.1 Atherosclerosis of renal artery
0.000 0.524 0.476
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.531 0.469
I70.9 Generalised and unspecified atherosclerosis
0.000 0.533 0.467
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.541 0.459
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.544 0.456
I70.8 Atherosclerosis of other arteries
0.000 0.546 0.454
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.547 0.453
I24.1 Dressler's syndrome
0.000 0.550 0.450
I72.2 Aneurysm of renal artery
0.000 0.552 0.447
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.553 0.447
I33.9 Acute endocarditis, unspecified
0.000 0.569 0.431
I78 Diseases of capillaries
0.000 0.572 0.428
I15 Secondary hypertension
0.000 0.575 0.425
I74.5 Embolism and thrombosis of iliac artery
0.000 0.577 0.423
I49.1 Atrial premature depolarisation
0.000 0.577 0.423
I49.5 Sick sinus syndrome
0.000 0.577 0.423
I49.8 Other specified cardiac arrhythmias
0.000 0.579 0.421
I11 Hypertensive heart disease
0.000 0.583 0.417
I70.0 Atherosclerosis of aorta
0.000 0.583 0.417
I72.9 Aneurysm of unspecified site
0.000 0.600 0.400
I31 Other diseases of pericardium
0.000 0.602 0.398
I37.9 Pulmonary valve disorder, unspecified
0.000 0.604 0.396
I37.8 Other pulmonary valve disorders
0.000 0.604 0.396
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.604 0.396
I37.0 Pulmonary valve stenosis
0.000 0.604 0.396
I72.1 Aneurysm of artery of upper extremity
0.000 0.605 0.394
I30.8 Other forms of acute pericarditis
0.000 0.607 0.393
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.607 0.393
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.611 0.389
I99 Other and unspecified disorders of circulatory system
0.000 0.612 0.388
Z95.3 Presence of xenogenic heart valve
0.000 0.617 0.383
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.621 0.379
I34.0 Mitral (valve) insufficiency
0.000 0.622 0.378
I77.6 Arteritis, unspecified
0.000 0.629 0.371
I72.0 Aneurysm of carotid artery
0.000 0.629 0.371
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.001 0.629 0.371
I36.8 Other nonrheumatic tricuspid valve disorders
0.001 0.629 0.371
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.001 0.629 0.371
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.001 0.629 0.371
I13 Hypertensive heart and renal disease
0.000 0.629 0.370
I28 Other diseases of pulmonary vessels
0.000 0.635 0.365
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.636 0.364
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.637 0.362
I01.8 Other acute rheumatic heart disease
0.000 0.637 0.362
I01.2 Acute rheumatic myocarditis
0.000 0.637 0.362
I01.1 Acute rheumatic endocarditis
0.000 0.637 0.362
I01.0 Acute rheumatic pericarditis
0.000 0.637 0.362
I02.9 Rheumatic chorea without heart involvement
0.000 0.637 0.362
I02.0 Rheumatic chorea with heart involvement
0.000 0.637 0.362
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.641 0.358
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.643 0.357
Z82.2 Family history of deafness and hearing loss
0.000 0.644 0.356
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.646 0.354
I77.2 Rupture of artery
0.000 0.649 0.351
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.650 0.350
I77.5 Necrosis of artery
0.000 0.651 0.348
I77.4 Coeliac artery compression syndrome
0.000 0.651 0.348
I77.3 Arterial fibromuscular dysplasia
0.000 0.651 0.348
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.652 0.348
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.654 0.346
I15.9 Seconday hypertension, unspecified
0.000 0.655 0.345
I49.2 Junctional premature depolarisation
0.000 0.655 0.344
I95 Hypotension
0.000 0.656 0.344
I05-I09 Chronic rheumatic heart diseases
0.000 0.659 0.341
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.659 0.341
I30.1 Infective pericarditis
0.000 0.660 0.340
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.665 0.335
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.665 0.335
I77.8 Other specified disorders of arteries and arterioles
0.000 0.670 0.330
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.674 0.326
I15.1 Hypertension secondary to other renal disorders
0.000 0.674 0.326
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.674 0.325
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.675 0.325
I51 Complications and ill-defined descriptions of heart disease
0.000 0.681 0.319
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.686 0.314
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.687 0.313
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.688 0.312
I30.9 Acute pericarditis, unspecified
0.000 0.690 0.310
I78.9 Disease of capillaries, unspecified
0.000 0.693 0.307
I28.8 Other specified diseases of pulmonary vessels
0.000 0.694 0.306
I15.8 Other secondary hypertension
0.000 0.695 0.305
I15.2 Hypertension secondary to endocrine disorders
0.000 0.695 0.305
I15.0 Renovascular hypertension
0.000 0.695 0.305
I42.0 Dilated cardiomyopathy
0.000 0.700 0.300
Z82.1 Family history of blindness and visual loss
0.000 0.700 0.300
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.700 0.300
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.701 0.299
I77.1 Stricture of artery
0.000 0.703 0.297
I77.0 Arteriovenous fistula, acquired
0.000 0.705 0.294
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.708 0.292
I95.1 Orthostatic hypotension
0.000 0.708 0.292
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.712 0.288
I49.4 Other and unspecified premature depolarisation
0.000 0.713 0.287
I31.8 Other specified diseases of pericardium
0.000 0.714 0.285
I31.2 Haemopericardium, not elsewhere classified
0.000 0.714 0.285
I95.9 Hypotension, unspecified
0.000 0.714 0.286
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.721 0.278
I78.8 Other diseases of capillaries
0.000 0.722 0.278
O34.2 Maternal care due to uterine scar from previous surgery
0.266 0.734 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.734 0.266
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.734 0.266
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.734 0.266
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.734 0.266
I31.0 Chronic adhesive pericarditis
0.000 0.737 0.263
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.738 0.262
I28.1 Aneurysm of pulmonary artery
0.000 0.738 0.262
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.738 0.262
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.751 0.249
I09 Other rheumatic heart diseases
0.000 0.751 0.249
I97.1 Other functional disturbances following cardiac surgery
0.000 0.753 0.247
I06 Rheumatic aortic valve diseases
0.000 0.755 0.245
I31.3 Pericardial effusion (noninflammatory)
0.000 0.760 0.240
I51.0 Cardiac septal defect, acquired
0.000 0.764 0.236
I37.1 Pulmonary valve insufficiency
0.001 0.764 0.235
I31.1 Chronic constrictive pericarditis
0.000 0.767 0.232
I51.6 Cardiovascular disease, unspecified
0.000 0.768 0.232
I07 Rheumatic tricuspid valve diseases
0.000 0.771 0.229
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.771 0.229
I51.9 Heart disease, unspecified
0.000 0.772 0.228
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.774 0.226
I31.9 Disease of pericardium, unspecified
0.000 0.775 0.225
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.775 0.225
I97.0 Postcardiotomy syndrome
0.000 0.775 0.225
I95.2 Hypotension due to drugs
0.000 0.780 0.220
I98 Other disorders of circulatory system in diseases classified elsewhere
0.001 0.782 0.218
I51.7 Cardiomegaly
0.000 0.793 0.207
I51.5 Myocardial degeneration
0.000 0.799 0.200
I51.8 Other ill-defined heart diseases
0.000 0.801 0.199
I10 Essential (primary) hypertension
0.000 0.802 0.198
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.806 0.194
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.806 0.194
I73.0 Raynaud's syndrome
0.000 0.810 0.190
Z82.3 Family history of stroke
0.000 0.815 0.185
I09.9 Rheumatic heart disease, unspecified
0.000 0.817 0.183
I95.8 Other hypotension
0.000 0.818 0.181
I95.0 Idiopathic hypotension
0.000 0.821 0.179
I09.8 Other specified rheumatic heart diseases
0.000 0.821 0.179
I09.2 Chronic rheumatic pericarditis
0.000 0.821 0.179
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.821 0.179
I09.0 Rheumatic myocarditis
0.000 0.821 0.179
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.822 0.178
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.824 0.176
I06.8 Other rheumatic aortic valve diseases
0.000 0.824 0.176
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.824 0.176
I06.1 Rheumatic aortic insufficiency
0.000 0.824 0.176
I06.0 Rheumatic aortic stenosis
0.000 0.824 0.176
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.001 0.824 0.174
I27 Other pulmonary heart diseases
0.000 0.825 0.175
I05 Rheumatic mitral valve diseases
0.000 0.827 0.173
I26 Pulmonary embolism
0.001 0.833 0.166
I07.9 Tricuspid valve disease, unspecified
0.000 0.835 0.164
I07.8 Other tricuspid valve diseases
0.000 0.835 0.164
I07.2 Tricuspid stenosis with insufficiency
0.000 0.835 0.164
I07.0 Tricuspid stenosis
0.000 0.835 0.164
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.001 0.843 0.156
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.001 0.843 0.156
I98.0 Cardiovascular syphilis
0.001 0.843 0.156
I47 Paroxysmal tachycardia
0.000 0.845 0.155
I07.1 Tricuspid insufficiency
0.000 0.851 0.149
I12 Hypertensive renal disease
0.000 0.854 0.146
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.001 0.856 0.143
O34 Maternal care for known or suspected abnormality of pelvic organs
0.143 0.857 0.000
S00.8 Superficial injury of other parts of head
0.000 0.857 0.143
I51.4 Myocarditis, unspecified
0.000 0.858 0.142
I27.9 Pulmonary heart disease, unspecified
0.000 0.860 0.140
I05.2 Mitral stenosis with insufficiency
0.000 0.862 0.138
I78.1 Naevus, nonneoplastic
0.000 0.865 0.135
Z95.4 Presence of other heart-valve replacement
0.000 0.866 0.134
I35.1 Aortic (valve) insufficiency
0.000 0.868 0.131
I49.0 Ventricular fibrillation and flutter
0.000 0.871 0.129
I27.8 Other specified pulmonary heart diseases
0.000 0.874 0.126
I27.1 Kyphoscoliotic heart disease
0.000 0.874 0.125
I05.8 Other mitral valve diseases
0.000 0.875 0.124
O34.0 Maternal care for congenital malformation of uterus
0.118 0.881 0.000
I05.1 Rheumatic mitral insufficiency
0.000 0.883 0.117
O34.8 Maternal care for other abnormalities of pelvic organs
0.117 0.883 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.001 0.891 0.108
S00 Superficial injury of head
0.000 0.891 0.109
I05.0 Mitral stenosis
0.000 0.891 0.109
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.103 0.897 0.000
O34.6 Maternal care for abnormality of vagina
0.103 0.897 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.103 0.897 0.000
O34.1 Maternal care for tumour of corpus uteri
0.102 0.898 0.000
S00.0 Superficial injury of scalp
0.000 0.898 0.102
I47.2 Ventricular tachycardia
0.000 0.902 0.098
O34.3 Maternal care for cervical incompetence
0.098 0.902 0.000
I08 Multiple valve diseases
0.000 0.903 0.097
O34.7 Maternal care for abnormality of vulva and perineum
0.097 0.903 0.000
O34.4 Maternal care for other abnormalities of cervix
0.095 0.904 0.000
S00.7 Multiple superficial injuries of head
0.000 0.907 0.093
I47.0 Reentry ventricular arrhythmia
0.000 0.911 0.088
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.915 0.085
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.918 0.081
S00.3 Superficial injury of nose
0.000 0.922 0.078
S00.1 Contusion of eyelid and periocular area
0.000 0.922 0.078
S00.5 Superficial injury of lip and oral cavity
0.000 0.924 0.075
I49.3 Ventricular premature depolarisation
0.001 0.930 0.069
I27.0 Primary pulmonary hypertension
0.000 0.933 0.067
I08.9 Multiple valve disease, unspecified
0.000 0.934 0.066
I12.9 Hypertensive renal disease without renal failure
0.000 0.934 0.066
S00.4 Superficial injury of ear
0.000 0.934 0.066
I05.9 Mitral valve disease, unspecified
0.000 0.935 0.064
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.936 0.064
I49.9 Cardiac arrhythmia, unspecified
0.000 0.936 0.064
I08.8 Other multiple valve diseases
0.000 0.939 0.061
S00.9 Superficial injury of head, part unspecified
0.000 0.942 0.058
I47.9 Paroxysmal tachycardia, unspecified
0.001 0.947 0.052
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.951 0.048
I27.2 Other secondary pulmonary hypertension
0.000 0.952 0.048
S00-S09 Injuries to the head
0.000 0.969 0.031
S01 Open wound of head
0.000 0.974 0.026
S01.9 Open wound of head, part unspecified
0.000 0.974 0.026
S02 Fracture of skull and facial bones
0.000 0.975 0.025
I08.0 Disorders of both mitral and aortic valves
0.000 0.976 0.024
S01.7 Multiple open wounds of head
0.000 0.976 0.024
S02.2 Fracture of nasal bones
0.000 0.976 0.024
S02.20 Fracture of nasal bones (closed)
0.000 0.977 0.023
S02.0 Fracture of vault of skull
0.000 0.977 0.023
I47.1 Supraventricular tachycardia
0.000 0.977 0.023
S01.1 Open wound of eyelid and periocular area
0.000 0.977 0.023
S08 Traumatic amputation of part of head
0.000 0.977 0.022
S07 Crushing injury of head
0.000 0.977 0.022
S04 Injury of cranial nerves
0.000 0.977 0.022
K05.3 Chronic periodontitis
0.023 0.977 0.000
S02.00 Fracture of vault of skull (closed)
0.000 0.978 0.022
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.978 0.021
S05 Injury of eye and orbit
0.000 0.979 0.021
S01.3 Open wound of ear
0.000 0.979 0.021
S09 Other and unspecified injuries of head
0.000 0.980 0.020
S01.2 Open wound of nose
0.000 0.980 0.020
I44 Atrioventricular and left bundle-branch block
0.000 0.982 0.018
S02.7 Multiple fractures involving skull and facial bones
0.000 0.982 0.018
S05.8 Other injuries of eye and orbit
0.000 0.982 0.018
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.982 0.018
S02.21 Fracture of nasal bones (open)
0.000 0.983 0.017
S09.8 Other specified injuries of head
0.000 0.983 0.017
S03.2 Dislocation of tooth
0.000 0.983 0.017
S02.01 Fracture of vault of skull (open)
0.000 0.983 0.017
S02.8 Fractures of other skull and facial bones
0.000 0.983 0.017
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.983 0.017
S04.9 Injury of unspecified cranial nerve
0.000 0.983 0.016
S04.8 Injury of other cranial nerves
0.000 0.983 0.016
S04.7 Injury of accessory nerve
0.000 0.983 0.016
S04.6 Injury of acoustic nerve
0.000 0.983 0.016
S04.5 Injury of facial nerve
0.000 0.983 0.016
S04.4 Injury of abducent nerve
0.000 0.983 0.016
S04.3 Injury of trigeminal nerve
0.000 0.983 0.016
S04.2 Injury of trochlear nerve
0.000 0.983 0.016
S04.1 Injury of oculomotor nerve
0.000 0.983 0.016
S04.0 Injury of optic nerve and pathways
0.000 0.983 0.016
S07.9 Crushing injury of head, part unspecified
0.000 0.983 0.016
S07.8 Crushing injury of other parts of head
0.000 0.983 0.016
S07.1 Crushing injury of skull
0.000 0.983 0.016
S07.0 Crushing injury of face
0.000 0.983 0.016
S08.9 Traumatic amputation of unspecified part of head
0.000 0.983 0.016
S08.8 Traumatic amputation of other parts of head
0.000 0.983 0.016
S08.1 Traumatic amputation of ear
0.000 0.983 0.016
S08.0 Avulsion of scalp
0.000 0.983 0.016
I60-I69 Cerebrovascular diseases
0.000 0.984 0.016
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head
0.000 0.984 0.015
S03.4 Sprain and strain of jaw
0.000 0.984 0.015
S03.3 Dislocation of other and unspecified parts of head
0.000 0.984 0.015
S03.0 Dislocation of jaw
0.000 0.984 0.015
S05.1 Contusion of eyeball and orbital tissues
0.000 0.984 0.016
S05.7 Avulsion of eye
0.000 0.984 0.016
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.984 0.016
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.984 0.016
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.984 0.016
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.984 0.016
S02.6 Fracture of mandible
0.000 0.984 0.015
S02.4 Fracture of malar and maxillary bones
0.000 0.984 0.015
S02.3 Fracture of orbital floor
0.000 0.985 0.015
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.985 0.015
S01.4 Open wound of cheek and temporomandibular area
0.000 0.985 0.015
S02.5 Fracture of tooth
0.000 0.985 0.015
S05.9 Injury of eye and orbit, part unspecified
0.000 0.985 0.015
S09.7 Multiple injuries of head
0.000 0.985 0.015
S09.2 Traumatic rupture of ear drum
0.000 0.985 0.015
S09.1 Injury of muscle and tendon of head
0.000 0.985 0.015
C71.9 Brain, unspecified
0.000 0.985 0.015
I44.4 Left anterior fascicular block
0.000 0.986 0.014
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.986 0.014
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.986 0.014
S09.0 Injury of blood vessels of head, not elsewhere classified
0.000 0.986 0.013
I44.5 Left posterior fascicular block
0.000 0.987 0.013
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.987 0.013
S01.5 Open wound of lip and oral cavity
0.000 0.987 0.013
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.987 0.013
S03.1 Dislocation of septal cartilage of nose
0.000 0.987 0.013
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.987 0.013
K05 Gingivitis and periodontal diseases
0.013 0.987 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.987 0.013
S02.1 Fracture of base of skull
0.000 0.987 0.012
S02.81 Fractures of other skull and facial bones (open)
0.000 0.988 0.012
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.988 0.012
C43.7 Malignant melanoma of lower limb, including hip
0.012 0.988 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.988 0.011
C71 Malignant neoplasm of brain
0.000 0.989 0.011
S02.61 Fracture of mandible (open)
0.000 0.989 0.011
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.989 0.011
S02.31 Fracture of orbital floor (open)
0.000 0.989 0.011
S02.51 Fracture of tooth (open)
0.000 0.989 0.011
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.989 0.011
K05.6 Periodontal disease, unspecified
0.011 0.989 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.989 0.011
C71.1 Frontal lobe
0.000 0.989 0.011
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.990 0.010
S09.9 Unspecified injury of head
0.000 0.990 0.010
I69 Sequelae of cerebrovascular disease
0.000 0.990 0.010
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.990 0.010
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.990 0.010
K05.1 Chronic gingivitis
0.010 0.990 0.000
I68.0 Cerebral amyloid angiopathy
0.000 0.990 0.009
K05.2 Acute periodontitis
0.009 0.991 0.000
K05.4 Periodontosis
0.009 0.991 0.000
K05.0 Acute gingivitis
0.009 0.991 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.991 0.009
I65.1 Occlusion and stenosis of basilar artery
0.000 0.991 0.009
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.991 0.009
C71.2 Temporal lobe
0.000 0.991 0.009

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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