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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs60541895
log Bayes Factor = 14.8112
Chromosome 1   position 42,088,393  (GRCh37) Explore rs60541895 on Ensembl!
Variant rs60541895 is part of Cluster X0049

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.994 0.006 0.000
Chapter XXI Factors influencing health status and contact with health services
0.991 0.009 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.990 0.010 0.000
I30-I52 Other forms of heart disease
0.987 0.013 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.986 0.014 0.000
Z53.0 Procedure not carried out because of contraindication
0.978 0.022 0.000
I25.1 Atherosclerotic heart disease
0.977 0.023 0.000
Chapter V Mental and behavioural disorders
0.973 0.027 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.970 0.030 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.967 0.033 0.000
Chapter VII Diseases of the eye and adnexa
0.966 0.034 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.955 0.045 0.000
E87.6 Hypokalaemia
0.955 0.045 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.951 0.049 0.000
I20 Angina pectoris
0.950 0.050 0.000
Z50 Care involving use of rehabilitation procedures
0.945 0.055 0.000
H53-H54 Visual disturbances and blindness
0.945 0.055 0.000
Chapter I Certain infectious and parasitic diseases
0.941 0.059 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.940 0.060 0.000
I44 Atrioventricular and left bundle-branch block
0.937 0.063 0.000
E86 Volume depletion
0.930 0.070 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.927 0.073 0.000
Chapter VI Diseases of the nervous system
0.926 0.074 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.921 0.079 0.000
Chapter X Diseases of the respiratory system
0.917 0.083 0.000
I25.2 Old myocardial infarction
0.917 0.083 0.000
E50-E64 Other nutritional deficiencies
0.917 0.083 0.000
I20.9 Angina pectoris, unspecified
0.909 0.091 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.902 0.098 0.000
R50-R69 General symptoms and signs
0.901 0.099 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.901 0.099 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.899 0.101 0.000
R55 Syncope and collapse
0.896 0.104 0.000
W00-W19 Falls
0.895 0.105 0.000
I24 Other acute ischaemic heart diseases
0.893 0.107 0.000
H54 Blindness and low vision
0.892 0.108 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.890 0.110 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.889 0.111 0.000
E10-E14 Diabetes mellitus
0.888 0.112 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.878 0.122 0.000
H25-H28 Disorders of lens
0.878 0.122 0.000
I22 Subsequent myocardial infarction
0.873 0.127 0.000
G40-G47 Episodic and paroxysmal disorders
0.871 0.129 0.000
J00-J06 Acute upper respiratory infections
0.871 0.129 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.869 0.131 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.868 0.132 0.000
I44.0 Atrioventricular block, first degree
0.868 0.132 0.000
H53 Visual disturbances
0.868 0.132 0.000
S60-S69 Injuries to the wrist and hand
0.864 0.136 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.862 0.138 0.000
E87.5 Hyperkalaemia
0.858 0.142 0.000
Z40 Prophylactic surgery
0.852 0.148 0.000
B95-B98 Bacterial, viral and other infectious agents
0.851 0.149 0.000
E87.2 Acidosis
0.851 0.149 0.000
J40-J47 Chronic lower respiratory diseases
0.849 0.151 0.000
Z53.8 Procedure not carried out for other reasons
0.847 0.153 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.846 0.154 0.000
I51 Complications and ill-defined descriptions of heart disease
0.844 0.156 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.844 0.156 0.000
G40 Epilepsy
0.844 0.156 0.000
H25 Senile cataract
0.840 0.160 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.838 0.162 0.000
I35 Nonrheumatic aortic valve disorders
0.837 0.163 0.000
F10.1 Harmful use
0.837 0.163 0.000
E53 Deficiency of other B group vitamins
0.835 0.165 0.000
R79 Other abnormal findings of blood chemistry
0.834 0.166 0.000
Z41 Procedures for purposes other than remedying health state
0.831 0.169 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.831 0.169 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.830 0.170 0.000
Chapter XI Diseases of the digestive system
0.829 0.171 0.000
Y52 Agents primarily affecting the cardiovascular system
0.827 0.172 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.824 0.176 0.000
Z48 Other surgical follow-up care
0.821 0.179 0.000
E83 Disorders of mineral metabolism
0.818 0.182 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.817 0.183 0.000
W19 Unspecified fall
0.815 0.185 0.000
Y40 Systemic antibiotics
0.813 0.187 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.812 0.188 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.811 0.189 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.811 0.189 0.000
J00 Acute nasopharyngitis [common cold]
0.810 0.189 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.808 0.192 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.806 0.194 0.000
I34 Nonrheumatic mitral valve disorders
0.806 0.194 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.806 0.194 0.000
I42 Cardiomyopathy
0.805 0.195 0.000
G40.9 Epilepsy, unspecified
0.805 0.195 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.803 0.196 0.000
I45 Other conduction disorders
0.803 0.197 0.000
E88 Other metabolic disorders
0.801 0.199 0.000
J44 Other chronic obstructive pulmonary disease
0.800 0.200 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.797 0.203 0.000
F30-F39 Mood [affective] disorders
0.796 0.204 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.796 0.204 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.795 0.205 0.000
K90-K93 Other diseases of the digestive system
0.792 0.208 0.000
I05-I09 Chronic rheumatic heart diseases
0.791 0.209 0.000
Y85 Sequelae of transport accidents
0.790 0.210 0.000
I44.7 Left bundle-branch block, unspecified
0.788 0.212 0.000
Z42 Follow-up care involving plastic surgery
0.788 0.212 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.788 0.212 0.000
E87.7 Fluid overload
0.787 0.213 0.000
H54.7 Unspecified visual loss
0.787 0.213 0.000
Chapter VIII Diseases of the ear and mastoid process
0.786 0.214 0.000
R53 Malaise and fatigue
0.785 0.215 0.000
Z50.2 Alcohol rehabilitation
0.783 0.217 0.000
I25.3 Aneurysm of heart
0.783 0.217 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.782 0.218 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.781 0.219 0.000
Z60 Problems related to social environment
0.779 0.221 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.779 0.221 0.000
G20-G26 Extrapyramidal and movement disorders
0.778 0.222 0.000
R00 Abnormalities of heart beat
0.777 0.223 0.000
E53.8 Deficiency of other specified B group vitamins
0.776 0.224 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.776 0.224 0.000
E11 Non-insulin-dependent diabetes mellitus
0.774 0.226 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.773 0.227 0.000
I50 Heart failure
0.773 0.227 0.000
E10 Insulin-dependent diabetes mellitus
0.773 0.227 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.771 0.229 0.000
E87.0 Hyperosmolality and hypernatraemia
0.768 0.231 0.000
R47-R49 Symptoms and signs involving speech and voice
0.768 0.232 0.000
X60-X84 Intentional self-harm
0.766 0.234 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.766 0.234 0.000
H53.0 Amblyopia ex anopsia
0.765 0.235 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.765 0.235 0.000
Chapter XXII Codes for special purposes
0.765 0.235 0.000
F10.2 Dependence syndrome
0.764 0.236 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.762 0.238 0.000
K92 Other diseases of digestive system
0.761 0.239 0.000
I44.3 Other and unspecified atrioventricular block
0.761 0.239 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.757 0.243 0.000
Y44 Agents primarily affecting blood constituents
0.755 0.245 0.000
Z63 Other problems related to primary support group, including family circumstances
0.754 0.246 0.000
E40-E46 Malnutrition
0.750 0.250 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.748 0.252 0.000
H54.9 Unspecified visual impairment (binocular)
0.747 0.253 0.000
V10-V19 Pedal cyclist injured in transport accident
0.747 0.253 0.000
B99-B99 Other infectious diseases
0.745 0.255 0.000
S20-S29 Injuries to the thorax
0.745 0.255 0.000
I33 Acute and subacute endocarditis
0.745 0.255 0.000
H25.1 Senile nuclear cataract
0.744 0.256 0.000
R74 Abnormal serum enzyme levels
0.744 0.256 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.743 0.257 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.742 0.258 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.742 0.258 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.739 0.261 0.000
O47 False labour
0.739 0.261 0.000
Z50.1 Other physical therapy
0.738 0.262 0.000
I20.0 Unstable angina
0.738 0.262 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.736 0.264 0.000
H53.1 Subjective visual disturbances
0.736 0.264 0.000
W19.4 Street and highway
0.734 0.266 0.000
T66-T78 Other and unspecified effects of external causes
0.734 0.266 0.000
S80-S89 Injuries to the knee and lower leg
0.733 0.267 0.000
Z49 Care involving dialysis
0.732 0.267 0.000
T51 Toxic effect of alcohol
0.731 0.269 0.000
R40 Somnolence, stupor and coma
0.730 0.270 0.000
W20-W49 Exposure to inanimate mechanical forces
0.728 0.272 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.728 0.272 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.727 0.273 0.000
Y85.0 Sequelae of motor-vehicle accident
0.727 0.273 0.000
I60-I69 Cerebrovascular diseases
0.726 0.274 0.000
S00-S09 Injuries to the head
0.726 0.274 0.000
F10.0 Acute intoxication
0.725 0.275 0.000
R30-R39 Symptoms and signs involving the urinary system
0.724 0.276 0.000
Z48.8 Other specified surgical follow-up care
0.724 0.276 0.000
I24.8 Other forms of acute ischaemic heart disease
0.724 0.276 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.723 0.277 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.722 0.278 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.722 0.278 0.000
R50 Fever of unknown origin
0.721 0.279 0.000
S64 Injury of nerves at wrist and hand level
0.721 0.279 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.718 0.282 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.717 0.283 0.000
H25.8 Other senile cataract
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.5 Ischaemic cardiomyopathy
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
E20-E35 Disorders of other endocrine glands
0.716 0.284 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.716 0.284 0.000
E87.4 Mixed disorder of acid-base balance
0.716 0.284 0.000
E87.3 Alkalosis
0.716 0.284 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.716 0.284 0.000
E55 Vitamin D deficiency
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
Y42.7 Androgens and anabolic congeners
0.714 0.286 0.000
L03 Cellulitis
0.713 0.287 0.000
I51.8 Other ill-defined heart diseases
0.713 0.287 0.000
R73 Elevated blood glucose level
0.713 0.287 0.000
I38 Endocarditis, valve unspecified
0.712 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.712 0.287 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.712 0.288 0.000
Y95 Nosocomial condition
0.712 0.288 0.000
R26 Abnormalities of gait and mobility
0.712 0.288 0.000
B07 Viral warts
0.712 0.288 0.000
G30-G32 Other degenerative diseases of the nervous system
0.711 0.289 0.000
R02 Gangrene, not elsewhere classified
0.711 0.289 0.000
H55-H59 Other disorders of eye and adnexa
0.711 0.289 0.000
O60-O75 Complications of labour and delivery
0.710 0.290 0.000
Z54 Convalescence
0.710 0.290 0.000
Z52 Donors of organs and tissues
0.710 0.290 0.000
Z44 Fitting and adjustment of external prosthetic device
0.710 0.290 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.709 0.291 0.000
J02 Acute pharyngitis
0.709 0.291 0.000
W19.2 School, other institution and public administrative area
0.708 0.292 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
I52 Other heart disorders in diseases classified elsewhere
0.708 0.292 0.000
I48 Atrial fibrillation and flutter
0.708 0.292 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.708 0.292 0.000
I41 Myocarditis in diseases classified elsewhere
0.708 0.292 0.000
I40 Acute myocarditis
0.708 0.292 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.708 0.292 0.000
I37 Pulmonary valve disorders
0.708 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.708 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.708 0.292 0.000
I30 Acute pericarditis
0.708 0.292 0.000
R54 Senility
0.708 0.292 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.707 0.293 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.707 0.293 0.000
G43 Migraine
0.706 0.294 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.706 0.294 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.705 0.295 0.000
I34.0 Mitral (valve) insufficiency
0.705 0.295 0.000
Z50.5 Speech therapy
0.704 0.296 0.000
R21 Rash and other nonspecific skin eruption
0.704 0.296 0.000
I20.1 Angina pectoris with documented spasm
0.703 0.297 0.000
H54.4 Blindness, one eye
0.702 0.298 0.000
Z40.8 Other prophylactic surgery
0.702 0.298 0.000
R27 Other lack of coordination
0.701 0.299 0.000
Z60.2 Living alone
0.699 0.301 0.000
K92.0 Haematemesis
0.699 0.301 0.000
F99-F99 Unspecified mental disorder
0.697 0.302 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.697 0.302 0.000
F80-F89 Disorders of psychological development
0.697 0.302 0.000
F70-F79 Mental retardation
0.697 0.302 0.000
F60-F69 Disorders of adult personality and behaviour
0.697 0.302 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.697 0.302 0.000
I35.1 Aortic (valve) insufficiency
0.697 0.303 0.000
I70 Atherosclerosis
0.696 0.304 0.000
T33-T35 Frostbite
0.695 0.305 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.695 0.305 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.695 0.305 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.695 0.305 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.695 0.305 0.000
T00-T07 Injuries involving multiple body regions
0.695 0.305 0.000
S10-S19 Injuries to the neck
0.695 0.305 0.000
A30-A49 Other bacterial diseases
0.693 0.306 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.693 0.307 0.000
H10-H13 Disorders of conjunctiva
0.693 0.307 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.692 0.308 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.692 0.308 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.691 0.309 0.000
T79-T79 Certain early complications of trauma
0.690 0.310 0.000
Y40.0 Penicillins
0.690 0.310 0.000
K50-K52 Noninfective enteritis and colitis
0.689 0.311 0.000
J46 Status asthmaticus
0.689 0.311 0.000
E89.0 Postprocedural hypothyroidism
0.687 0.313 0.000
G90-G99 Other disorders of the nervous system
0.686 0.314 0.000
E83.4 Disorders of magnesium metabolism
0.685 0.315 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.685 0.315 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.685 0.315 0.000
H65-H75 Diseases of middle ear and mastoid
0.683 0.317 0.000
L40-L45 Papulosquamous disorders
0.683 0.317 0.000
R41.3 Other amnesia
0.682 0.318 0.000
Y59 Other and unspecified vaccines and biological substances
0.682 0.318 0.000
Y58 Bacterial vaccines
0.682 0.318 0.000
Y57 Other and unspecified drugs and medicaments
0.682 0.318 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.682 0.318 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.682 0.318 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.682 0.318 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.682 0.318 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.682 0.318 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.682 0.318 0.000
Y48 Anaesthetics and therapeutic gases
0.682 0.318 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.682 0.318 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.682 0.318 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.682 0.318 0.000
H54.0 Blindness, both eyes
0.682 0.318 0.000
K92.1 Melaena
0.682 0.318 0.000
K90 Intestinal malabsorption
0.681 0.319 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.681 0.319 0.000
L20-L30 Dermatitis and eczema
0.681 0.319 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.680 0.320 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.678 0.322 0.000
R00.2 Palpitations
0.678 0.322 0.000
Z50.6 Orthoptic training
0.678 0.322 0.000
Z50.3 Drug rehabilitation
0.678 0.322 0.000
Z22 Carrier of infectious disease
0.677 0.323 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.677 0.323 0.000
S40-S49 Injuries to the shoulder and upper arm
0.677 0.323 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.676 0.324 0.000
H25.9 Senile cataract, unspecified
0.676 0.324 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.675 0.324 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.675 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.675 0.325 0.000
B65-B83 Helminthiases
0.675 0.325 0.000
B50-B64 Protozoal diseases
0.675 0.325 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.675 0.325 0.000
B15-B19 Viral hepatitis
0.675 0.325 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.675 0.325 0.000
A80-A89 Viral infections of the central nervous system
0.675 0.325 0.000
A75-A79 Rickettsioses
0.675 0.325 0.000
A70-A74 Other diseases caused by chlamydiae
0.675 0.325 0.000
A65-A69 Other spirochaetal diseases
0.675 0.325 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.675 0.325 0.000
A20-A28 Certain zoonotic bacterial diseases
0.675 0.325 0.000
A15-A19 Tuberculosis
0.675 0.325 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.675 0.325 0.000
E61 Deficiency of other nutrient elements
0.674 0.326 0.000
J60-J70 Lung diseases due to external agents
0.674 0.326 0.000
O85-O92 Complications predominantly related to the puerperium
0.674 0.326 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.673 0.327 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.672 0.328 0.000
I45.2 Bifascicular block
0.672 0.328 0.000
I44.6 Other and unspecified fascicular block
0.671 0.328 0.000
I44.5 Left posterior fascicular block
0.671 0.328 0.000
I44.4 Left anterior fascicular block
0.671 0.328 0.000
H53.8 Other visual disturbances
0.671 0.328 0.000
H52 Disorders of refraction and accommodation
0.671 0.329 0.000
T43.2 Other and unspecified antidepressants
0.670 0.330 0.000
F10.3 Withdrawal state
0.669 0.331 0.000
J42 Unspecified chronic bronchitis
0.667 0.333 0.000
S90-S99 Injuries to the ankle and foot
0.667 0.333 0.000
R42 Dizziness and giddiness
0.666 0.334 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.666 0.334 0.000
W06 Fall involving bed
0.665 0.335 0.000
R03.1 Nonspecific low blood-pressure reading
0.665 0.335 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.665 0.335 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.664 0.336 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.664 0.336 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.664 0.336 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.664 0.336 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.664 0.336 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.664 0.336 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.664 0.336 0.000
F11 Mental and behavioural disorders due to use of opioids
0.664 0.336 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.664 0.336 0.000
A00-A09 Intestinal infectious diseases
0.664 0.336 0.000
G70-G73 Diseases of myoneural junction and muscle
0.664 0.336 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.664 0.336 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.664 0.336 0.000
H53.2 Diplopia
0.664 0.336 0.000
I73 Other peripheral vascular diseases
0.663 0.337 0.000
R60 Oedema, not elsewhere classified
0.661 0.339 0.000
O21 Excessive vomiting in pregnancy
0.661 0.339 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.660 0.339 0.000
R77 Other abnormalities of plasma proteins
0.660 0.339 0.000
R76 Other abnormal immunological findings in serum
0.660 0.339 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.660 0.339 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.660 0.339 0.000
R71 Abnormality of red blood cells
0.660 0.339 0.000
G20 Parkinson's disease
0.660 0.340 0.000
O00-O08 Pregnancy with abortive outcome
0.660 0.340 0.000
I77 Other disorders of arteries and arterioles
0.660 0.340 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.659 0.341 0.000
I44.2 Atrioventricular block, complete
0.658 0.342 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.657 0.343 0.000
E63 Other nutritional deficiencies
0.657 0.343 0.000
E56 Other vitamin deficiencies
0.657 0.343 0.000
E51 Thiamine deficiency
0.657 0.343 0.000
E50 Vitamin A deficiency
0.657 0.343 0.000
E60 Dietary zinc deficiency
0.657 0.343 0.000
E59 Dietary selenium deficiency
0.657 0.343 0.000
E58 Dietary calcium deficiency
0.657 0.343 0.000
E54 Ascorbic acid deficiency
0.657 0.343 0.000
E52 Niacin deficiency [pellagra]
0.657 0.343 0.000
Z43 Attention to artificial openings
0.656 0.344 0.000
H25.0 Senile incipient cataract
0.656 0.344 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.653 0.347 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.653 0.347 0.000
H43-H45 Disorders of vitreous body and globe
0.652 0.348 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.651 0.348 0.000
I51.7 Cardiomegaly
0.651 0.349 0.000
Y88 Sequelae of surgical and medical care as external cause
0.651 0.349 0.000
S70-S79 Injuries to the hip and thigh
0.650 0.350 0.000
E83.3 Disorders of phosphorus metabolism
0.650 0.350 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.649 0.351 0.000
E11.9 Without complications
0.649 0.351 0.000
I21 Acute myocardial infarction
0.648 0.352 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.648 0.352 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.647 0.353 0.000
R46 Symptoms and signs involving appearance and behaviour
0.646 0.354 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.646 0.354 0.000
R43 Disturbances of smell and taste
0.646 0.354 0.000
O47.0 False labour before 37 completed weeks of gestation
0.646 0.354 0.000
R68 Other general symptoms and signs
0.646 0.354 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.646 0.354 0.000
R62 Lack of expected normal physiological development
0.646 0.354 0.000
R57 Shock, not elsewhere classified
0.646 0.354 0.000
R64 Cachexia
0.646 0.354 0.000
R58 Haemorrhage, not elsewhere classified
0.646 0.354 0.000
L10-L14 Bullous disorders
0.646 0.354 0.000
O20 Haemorrhage in early pregnancy
0.645 0.355 0.000
I45.6 Preexcitation syndrome
0.645 0.355 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.645 0.355 0.000
E00-E07 Disorders of thyroid gland
0.645 0.355 0.000
E10.9 Without complications
0.645 0.355 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.644 0.356 0.000
F10.9 Unspecified mental and behavioural disorder
0.644 0.356 0.000
F10.8 Other mental and behavioural disorders
0.644 0.356 0.000
F10.7 Residual and late-onset psychotic disorder
0.644 0.356 0.000
F10.6 Amnesic syndrome
0.644 0.356 0.000
F10.5 Psychotic disorder
0.644 0.356 0.000
F10.4 Withdrawal state with delirium
0.644 0.356 0.000
T51.0 Ethanol
0.644 0.356 0.000
S62 Fracture at wrist and hand level
0.642 0.357 0.000
R45 Symptoms and signs involving emotional state
0.642 0.358 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.642 0.358 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.642 0.358 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.642 0.358 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.642 0.358 0.000
W18 Other fall on same level
0.641 0.359 0.000
W17 Other fall from one level to another
0.641 0.359 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.641 0.359 0.000
W15 Fall from cliff
0.641 0.359 0.000
W14 Fall from tree
0.641 0.359 0.000
W13 Fall from, out of or through building or structure
0.641 0.359 0.000
W12 Fall on and from scaffolding
0.641 0.359 0.000
W11 Fall on and from ladder
0.641 0.359 0.000
W10 Fall on and from stairs and steps
0.641 0.359 0.000
W09 Fall involving playground equipment
0.641 0.359 0.000
W08 Fall involving other furniture
0.641 0.359 0.000
W07 Fall involving chair
0.641 0.359 0.000
W05 Fall involving wheelchair
0.641 0.359 0.000
W04 Fall while being carried or supported by other persons
0.641 0.359 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.641 0.359 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.641 0.359 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.641 0.359 0.000
W00 Fall on same level involving ice and snow
0.641 0.359 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.641 0.359 0.000
I05 Rheumatic mitral valve diseases
0.641 0.359 0.000
S67 Crushing injury of wrist and hand
0.641 0.359 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.641 0.359 0.000
I24.1 Dressler's syndrome
0.640 0.359 0.000
H54.6 Unqualified visual loss, one eye
0.640 0.360 0.000
H54.5 Low vision, one eye
0.640 0.360 0.000
H54.3 Unqualified visual loss, both eyes
0.640 0.360 0.000
H54.2 Low vision, both eyes
0.640 0.360 0.000
H54.1 Blindness, one eye, low vision, other eye
0.640 0.360 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.639 0.361 0.000
Z65 Problems related to other psychosocial circumstances
0.638 0.362 0.000
Z64 Problems related to certain psychosocial circumstances
0.638 0.362 0.000
Z62 Other problems related to upbringing
0.638 0.362 0.000
Z61 Problems related to negative life events in childhood
0.638 0.362 0.000
Z59 Problems related to housing and economic circumstances
0.638 0.362 0.000
Z58 Problems related to physical environment
0.638 0.362 0.000
Z56 Problems related to employment and unemployment
0.638 0.362 0.000
Z55 Problems related to education and literacy
0.638 0.362 0.000
S50-S59 Injuries to the elbow and forearm
0.638 0.362 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.637 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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