TreeWAS – Variant ID: rs6074578

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z94.8 Other transplanted organ and tissue status	0.727	0.273	0.000
Z94 Transplanted organ and tissue status	0.714	0.286	0.000
Z94.4 Liver transplant status	0.688	0.312	0.000
Z94.1 Heart transplant status	0.639	0.361	0.000
Z94.7 Corneal transplant status	0.611	0.389	0.000
Z94.0 Kidney transplant status	0.598	0.402	0.000
Z94.3 Heart and lungs transplant status	0.558	0.442	0.000
Z94.6 Bone transplant status	0.538	0.462	0.000
E86 Volume depletion	0.525	0.475	0.000
Z94.9 Transplanted organ and tissue status, unspecified	0.496	0.503	0.000
Z94.5 Skin transplant status	0.493	0.507	0.000
Z94.2 Lung transplant status	0.460	0.539	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.931	0.069
I08 Multiple valve diseases	0.000	0.938	0.062
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.939	0.061
I05-I09 Chronic rheumatic heart diseases	0.000	0.947	0.053
I05 Rheumatic mitral valve diseases	0.000	0.948	0.052
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.949	0.051
I05.2 Mitral stenosis with insufficiency	0.000	0.951	0.049
I08.9 Multiple valve disease, unspecified	0.000	0.954	0.046
I05.1 Rheumatic mitral insufficiency	0.000	0.956	0.044
I09 Other rheumatic heart diseases	0.000	0.959	0.041
I05.9 Mitral valve disease, unspecified	0.000	0.959	0.041
I05.0 Mitral stenosis	0.000	0.960	0.040
I06 Rheumatic aortic valve diseases	0.000	0.960	0.040
I05.8 Other mitral valve diseases	0.000	0.963	0.036
Z83.3 Family history of diabetes mellitus	0.000	0.964	0.036
I09.9 Rheumatic heart disease, unspecified	0.000	0.967	0.033
I07 Rheumatic tricuspid valve diseases	0.000	0.968	0.032
I06.0 Rheumatic aortic stenosis	0.000	0.969	0.031
I09.8 Other specified rheumatic heart diseases	0.000	0.970	0.030
I09.2 Chronic rheumatic pericarditis	0.000	0.970	0.030
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.970	0.030
I09.0 Rheumatic myocarditis	0.000	0.970	0.030
I06.1 Rheumatic aortic insufficiency	0.000	0.970	0.029
E70-E90 Metabolic disorders	0.029	0.971	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.971	0.029
I06.8 Other rheumatic aortic valve diseases	0.000	0.971	0.029
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.971	0.029
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.028	0.972	0.000
E89.0 Postprocedural hypothyroidism	0.026	0.974	0.000
E73 Lactose intolerance	0.025	0.975	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.024	0.976	0.000
E79 Disorders of purine and pyrimidine metabolism	0.024	0.976	0.000
E84 Cystic fibrosis	0.023	0.977	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.023	0.977	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.977	0.023
I07.8 Other tricuspid valve diseases	0.000	0.977	0.023
I07.2 Tricuspid stenosis with insufficiency	0.000	0.977	0.023
I07.0 Tricuspid stenosis	0.000	0.977	0.023
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.023	0.977	0.000
E73.9 Lactose intolerance, unspecified	0.022	0.978	0.000
E77 Disorders of glycoprotein metabolism	0.021	0.979	0.000
E76 Disorders of glycosaminoglycan metabolism	0.021	0.979	0.000
E72 Other disorders of amino-acid metabolism	0.021	0.979	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.021	0.979	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.021	0.979	0.000
E89.2 Postprocedural hypoparathyroidism	0.021	0.979	0.000
E74 Other disorders of carbohydrate metabolism	0.021	0.979	0.000
E89.4 Postprocedural ovarian failure	0.020	0.980	0.000
E89.1 Postprocedural hypoinsulinaemia	0.020	0.980	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.020	0.980	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.020	0.980	0.000
E89.5 Postprocedural testicular hypofunction	0.020	0.980	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.980	0.020
E70 Disorders of aromatic amino-acid metabolism	0.020	0.980	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.019	0.980	0.000
E84.9 Cystic fibrosis, unspecified	0.019	0.981	0.000
E75.5 Other lipid storage disorders	0.019	0.981	0.000
E73.8 Other lactose intolerance	0.018	0.982	0.000
E73.1 Secondary lactase deficiency	0.018	0.982	0.000
E73.0 Congenital lactase deficiency	0.018	0.982	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.017	0.983	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.017	0.983	0.000
E79.1 Lesch-Nyhan syndrome	0.017	0.983	0.000
E84.8 Cystic fibrosis with other manifestations	0.017	0.983	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.017	0.983	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.017	0.983	0.000
E75.6 Lipid storage disorder, unspecified	0.017	0.983	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.017	0.983	0.000
E75.3 Sphingolipidosis, unspecified	0.017	0.983	0.000
E75.2 Other sphingolipidosis	0.017	0.983	0.000
E75.1 Other gangliosidosis	0.017	0.983	0.000
E75.0 GM2 gangliosidosis	0.017	0.983	0.000
I08.8 Other multiple valve diseases	0.001	0.983	0.016
I07.1 Tricuspid insufficiency	0.000	0.984	0.016
S22.40 Multiple fractures of ribs (closed)	0.016	0.984	0.000
E85 Amyloidosis	0.016	0.984	0.000
E71.3 Disorders of fatty-acid metabolism	0.015	0.984	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.015	0.984	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.015	0.984	0.000
E71.0 Maple-syrup-urine disease	0.015	0.984	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.015	0.984	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.015	0.984	0.000
E72.5 Disorders of glycine metabolism	0.015	0.984	0.000
E72.4 Disorders of ornithine metabolism	0.015	0.984	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.015	0.984	0.000
E72.2 Disorders of urea cycle metabolism	0.015	0.984	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.015	0.984	0.000
E72.0 Disorders of amino-acid transport	0.015	0.984	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.015	0.984	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.015	0.984	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.015	0.984	0.000
E76.2 Other mucopolysaccharidoses	0.015	0.984	0.000
E76.1 Mucopolysaccharidosis, type II	0.015	0.984	0.000
E76.0 Mucopolysaccharidosis, type I	0.015	0.984	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.015	0.984	0.000
E77.8 Other disorders of glycoprotein metabolism	0.015	0.984	0.000
E77.1 Defects in glycoprotein degradation	0.015	0.984	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.015	0.984	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.015	0.985	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.015	0.985	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.015	0.985	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.015	0.985	0.000
E74.2 Disorders of galactose metabolism	0.015	0.985	0.000
E74.1 Disorders of fructose metabolism	0.015	0.985	0.000
Y44.2 Anticoagulants	0.015	0.985	0.000
E89.3 Postprocedural hypopituitarism	0.015	0.985	0.000
E74.0 Glycogen storage disease	0.015	0.985	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.014	0.985	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.014	0.985	0.000
E70.2 Disorders of tyrosine metabolism	0.014	0.985	0.000
E70.1 Other hyperphenylalaninaemias	0.014	0.985	0.000
E70.0 Classical phenylketonuria	0.014	0.985	0.000
E70.3 Albinism	0.013	0.987	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.013	0.987	0.000
E85.3 Secondary systemic amyloidosis	0.013	0.987	0.000
E83 Disorders of mineral metabolism	0.013	0.987	0.000
E88 Other metabolic disorders	0.012	0.988	0.000
T18.1 Foreign body in oesophagus	0.012	0.988	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.011	0.988	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.011	0.988	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.011	0.988	0.000
E85.8 Other amyloidosis	0.011	0.989	0.000
W19.9 Unspecified place	0.011	0.989	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.011	0.989	0.000
E83.3 Disorders of phosphorus metabolism	0.011	0.989	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.010	0.990	0.000
E80.2 Other porphyria	0.010	0.990	0.000
T18 Foreign body in alimentary tract	0.010	0.990	0.000
E29.1 Testicular hypofunction	0.010	0.990	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.009	0.990	0.000
E80.5 Crigler-Najjar syndrome	0.009	0.990	0.000
E80.3 Defects of catalase and peroxydase	0.009	0.990	0.000
E80.0 Hereditary erythropoietic porphyria	0.009	0.990	0.000
E83.8 Other disorders of mineral metabolism	0.009	0.991	0.000
E83.2 Disorders of zinc metabolism	0.009	0.991	0.000
E83.0 Disorders of copper metabolism	0.009	0.991	0.000
E83.5 Disorders of calcium metabolism	0.009	0.991	0.000
E88.3 Tumour lysis syndrome	0.009	0.991	0.000
T17 Foreign body in respiratory tract	0.009	0.991	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.009	0.991	0.000
Y44 Agents primarily affecting blood constituents	0.009	0.991	0.000
E85.9 Amyloidosis, unspecified	0.008	0.991	0.000
K81.0 Acute cholecystitis	0.000	0.991	0.009
E88.2 Lipomatosis, not elsewhere classified	0.008	0.991	0.000
H61.2 Impacted cerumen	0.008	0.992	0.000
E88.9 Metabolic disorder, unspecified	0.008	0.992	0.000
H43.1 Vitreous haemorrhage	0.000	0.992	0.008
E80.1 Porphyria cutanea tarda	0.008	0.992	0.000
E88.8 Other specified metabolic disorders	0.008	0.992	0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.008	0.992	0.000
T18.2 Foreign body in stomach	0.008	0.992	0.000
T18.5 Foreign body in anus and rectum	0.008	0.992	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.008	0.992	0.000
E85.4 Organ-limited amyloidosis	0.007	0.992	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.008	0.992	0.000
T18.0 Foreign body in mouth	0.008	0.992	0.000
T15 Foreign body on external eye	0.008	0.992	0.000
S22.4 Multiple fractures of ribs	0.008	0.992	0.000
H61.1 Non-infective disorders of pinna	0.007	0.993	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.007	0.993	0.000
T18.4 Foreign body in colon	0.007	0.993	0.000
T18.3 Foreign body in small intestine	0.007	0.993	0.000
T19 Foreign body in genito-urinary tract	0.007	0.993	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.007	0.993	0.000
E80.4 Gilbert's syndrome	0.007	0.993	0.000
Y44.6 Natural blood and blood products	0.007	0.993	0.000
E80.6 Other disorders of bilirubin metabolism	0.007	0.993	0.000
T17.3 Foreign body in larynx	0.007	0.993	0.000
T16 Foreign body in ear	0.007	0.993	0.000
T15.0 Foreign body in cornea	0.007	0.993	0.000
T17.4 Foreign body in trachea	0.007	0.993	0.000
T17.1 Foreign body in nostril	0.007	0.993	0.000
T17.0 Foreign body in nasal sinus	0.007	0.993	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.006	0.993	0.000
Y44.7 Plasma substitutes	0.006	0.993	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.006	0.993	0.000
T17.5 Foreign body in bronchus	0.006	0.993	0.000
G57.6 Lesion of plantar nerve	0.000	0.994	0.006
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.006	0.994	0.000
T19.1 Foreign body in bladder	0.006	0.994	0.000
H61 Other disorders of external ear	0.006	0.994	0.000
H61.8 Other specified disorders of external ear	0.006	0.994	0.000
D24 Benign neoplasm of breast	0.000	0.994	0.006
T15.9 Foreign body on external eye, unspecified	0.006	0.994	0.000
T15.8 Foreign body in other and multiple parts of external eye	0.006	0.994	0.000
S22.41 Multiple fractures of ribs (open)	0.006	0.994	0.000
T15.1 Foreign body in conjunctival sac	0.005	0.994	0.000
T19.9 Foreign body in genito-urinary tract, part unspecified	0.005	0.994	0.000
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.005	0.994	0.000
T19.3 Foreign body in uterus [any part]	0.005	0.994	0.000
T19.0 Foreign body in urethra	0.005	0.994	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.005	0.994	0.000
T19.2 Foreign body in vulva and vagina	0.005	0.995	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.005	0.995	0.000
R26 Abnormalities of gait and mobility	0.005	0.995	0.000
H06.2 Dysthyroid exophthalmos	0.005	0.995	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.005	0.995	0.000
E83.4 Disorders of magnesium metabolism	0.005	0.995	0.000
W19 Unspecified fall	0.005	0.995	0.000
G63.2 Diabetic polyneuropathy	0.000	0.995	0.005
E29 Testicular dysfunction	0.005	0.995	0.000
Q21.1 Atrial septal defect	0.000	0.995	0.005
T17.2 Foreign body in pharynx	0.005	0.995	0.000
W19.3 Sports and athletics area	0.005	0.995	0.000
K81.1 Chronic cholecystitis	0.000	0.996	0.004
Y44.5 Thrombolytic drugs	0.004	0.996	0.000
H43.2 Crystalline deposits in vitreous body	0.000	0.996	0.004
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.996	0.004
W19.1 Residential institution	0.004	0.996	0.000
W19.6 Industrial and construction area	0.004	0.996	0.000
R26.1 Paralytic gait	0.004	0.996	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.004	0.996	0.000
C69.3 Choroid	0.004	0.996	0.000
K81 Cholecystitis	0.000	0.996	0.004
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.004	0.996	0.000
W29.9 Unspecified place	0.000	0.996	0.004
W19.8 Other specified place	0.004	0.996	0.000
W19.5 Trade and service area	0.004	0.996	0.000
W19.0 Home	0.004	0.996	0.000
W19.7 Farm	0.004	0.996	0.000
H43 Disorders of vitreous body	0.000	0.996	0.004
H61.0 Perichondritis of external ear	0.004	0.996	0.000
S81.0 Open wound of knee	0.004	0.996	0.000
E29.9 Testicular dysfunction, unspecified	0.004	0.996	0.000
E29.8 Other testicular dysfunction	0.004	0.996	0.000
E29.0 Testicular hyperfunction	0.004	0.996	0.000
H43.9 Disorder of vitreous body, unspecified	0.000	0.996	0.004
E87 Other disorders of fluid, electrolyte and acid-base balance	0.004	0.996	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.004	0.996	0.000
S82.00 Fracture of patella (closed)	0.004	0.996	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.996	0.004
I63.8 Other cerebral infarction	0.000	0.996	0.004
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.996	0.004
G57.8 Other mononeuropathies of lower limb	0.000	0.997	0.003
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.003	0.997	0.000
R26.3 Immobility	0.003	0.997	0.000
Z42 Follow-up care involving plastic surgery	0.003	0.997	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
H61.9 Disorder of external ear, unspecified	0.003	0.997	0.000
G57 Mononeuropathies of lower limb	0.000	0.997	0.003
W19.09 Unspecified fall; Home; During unspecified activity	0.003	0.997	0.000
W19.08 Unspecified fall; Home; While engaged in other specified activities	0.003	0.997	0.000
W19.59 Unspecified fall; Trade and service area; During unspecified activity	0.003	0.997	0.000
W19.81 Unspecified fall; Other specified places; While engaged in leisure activity	0.003	0.997	0.000
E23.0 Hypopituitarism	0.003	0.997	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.003	0.997	0.000
H43.0 Vitreous prolapse	0.000	0.997	0.003
Z42.9 Follow-up care involving plastic surgery, unspecified	0.003	0.997	0.000
F31.9 Bipolar affective disorder, unspecified	0.003	0.997	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.997	0.003
Z34.8 Supervision of other normal pregnancy	0.003	0.997	0.000
K81.8 Other cholecystitis	0.000	0.997	0.003
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.997	0.003
E87.4 Mixed disorder of acid-base balance	0.003	0.997	0.000
W19.4 Street and highway	0.003	0.997	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
W19.2 School, other institution and public administrative area	0.003	0.997	0.000
T59.8 Other specified gases, fumes and vapours	0.000	0.997	0.003
E05.0 Thyrotoxicosis with diffuse goitre	0.003	0.997	0.000
H61.3 Acquired stenosis of external ear canal	0.002	0.997	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.997	0.003
I63 Cerebral infarction	0.000	0.997	0.003
Z42.8 Follow-up care involving plastic surgery of other body part	0.003	0.997	0.000
E87.2 Acidosis	0.003	0.997	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.997	0.003
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.003	0.997	0.000
F32.0 Mild depressive episode	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
R39.1 Other difficulties with micturition	0.003	0.997	0.000
H92.0 Otalgia	0.003	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.003	0.997	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.997	0.003
G57.4 Lesion of medial popliteal nerve	0.000	0.997	0.002
G57.2 Lesion of femoral nerve	0.000	0.997	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.997	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.997	0.003
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.997	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.997	0.003
T90.4 Sequelae of injury of eye and orbit	0.003	0.997	0.000
G57.1 Meralgia paraesthetica	0.000	0.997	0.002
R26.0 Ataxic gait	0.002	0.997	0.000
S82.0 Fracture of patella	0.002	0.997	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S82.01 Fracture of patella (open)	0.002	0.998	0.000
G57.0 Lesion of sciatic nerve	0.000	0.998	0.002
W07.0 Home	0.002	0.998	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.002	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
T31.0 Burns involving less than 10% of body surface	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
C69.2 Retina	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
S81 Open wound of lower leg	0.002	0.998	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.000	0.998	0.002
G57.3 Lesion of lateral popliteal nerve	0.000	0.998	0.002
H49.1 Fourth [trochlear] nerve palsy	0.000	0.998	0.002
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.998	0.002
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.998	0.002
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.998	0.002
F31 Bipolar affective disorder	0.002	0.998	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.998	0.002
C69.0 Conjunctiva	0.002	0.998	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.998	0.002
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
L73.2 Hidradenitis suppurativa	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000
F30 Manic episode	0.002	0.998	0.000
F39 Unspecified mood [affective] disorder	0.002	0.998	0.000
Z83 Family history of other specific disorders	0.000	0.998	0.002
C69.6 Orbit	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
R25.2 Cramp and spasm	0.002	0.998	0.000
E87.0 Hyperosmolality and hypernatraemia	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
F32 Depressive episode	0.002	0.998	0.000
K09.2 Other cysts of jaw	0.002	0.998	0.000
Z52.4 Kidney donor	0.002	0.998	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.998	0.002
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.998	0.002
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.998	0.002
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.998	0.002
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.998	0.002
G63.1 Polyneuropathy in neoplastic disease	0.000	0.998	0.002
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
M13.09 Polyarthritis, unspecified (Site unspecified)	0.002	0.998	0.000
D04.2 Skin of ear and external auricular canal	0.000	0.998	0.002
K66.9 Disorder of peritoneum, unspecified	0.000	0.998	0.002
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
Z93.6 Other artificial openings of urinary tract status	0.000	0.998	0.002
C25.0 Head of pancreas	0.002	0.998	0.000
C69.9 Eye, unspecified	0.002	0.998	0.000
Z83.6 Family history of diseases of the respiratory system	0.000	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
F30-F39 Mood [affective] disorders	0.002	0.998	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.002	0.998	0.000
G57.5 Tarsal tunnel syndrome	0.000	0.998	0.002
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
W07 Fall involving chair	0.002	0.998	0.000
W29 Contact with other powered hand tools and household machinery	0.000	0.998	0.002
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
F32.8 Other depressive episodes	0.002	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
Z59.1 Inadequate housing	0.002	0.998	0.000
Z59 Problems related to housing and economic circumstances	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.998	0.002
R27.8 Other and unspecified lack of coordination	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
B50.9 Plasmodium falciparum malaria, unspecified	0.002	0.998	0.000
E87.5 Hyperkalaemia	0.002	0.998	0.000
D04.4 Skin of scalp and neck	0.000	0.998	0.002
D04.1 Skin of eyelid, including canthus	0.000	0.998	0.002
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Z59.0 Homelessness	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.002	0.998	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.002	0.998	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.002	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.998	0.002
K66.0 Peritoneal adhesions	0.000	0.998	0.002
Z47 Other orthopaedic follow-up care	0.002	0.998	0.000
F30.0 Hypomania	0.002	0.998	0.000
F32.1 Moderate depressive episode	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998	0.000
C18.1 Appendix	0.002	0.998	0.000
F30.8 Other manic episodes	0.002	0.998	0.000
F52.2 Failure of genital response	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
R40.2 Coma, unspecified	0.000	0.998	0.002
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Z83.0 Family history of human immunodeficiency virus [HIV]	0.000	0.998	0.002
Y58 Bacterial vaccines	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
B25.9 Cytomegaloviral disease, unspecified	0.002	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.002	0.998	0.000
W07.5 Trade and service area	0.002	0.998	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.002	0.998	0.000
E83.1 Disorders of iron metabolism	0.002	0.998	0.000
E87.3 Alkalosis	0.002	0.998	0.000
G46.4 Cerebellar stroke syndrome	0.002	0.998	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.002	0.998	0.000
D04 Carcinoma in situ of skin	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.998	0.001
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.998	0.002
Y45.1 Salicylates	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
R21 Rash and other nonspecific skin eruption	0.002	0.998	0.000
M54.36 Sciatica (Lumbar region)	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
W15.8 Other specified place	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
D04.7 Skin of lower limb, including hip	0.000	0.998	0.002
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
W07.9 Unspecified place	0.002	0.998	0.000
W29.5 Trade and service area	0.000	0.998	0.002
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.002	0.998	0.000
F30.1 Mania without psychotic symptoms	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.002	0.998	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.998	0.002
W02.9 Unspecified place	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
F38 Other mood [affective] disorders	0.002	0.998	0.000
F34 Persistent mood [affective] disorders	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.002	0.998	0.000
W07.2 School, other institution and public administrative area	0.002	0.998	0.000
W07.8 Other specified place	0.002	0.998	0.000
W07.7 Farm	0.002	0.998	0.000
W07.6 Industrial and construction area	0.002	0.998	0.000
W07.4 Street and highway	0.002	0.998	0.000
W07.3 Sports and athletics area	0.002	0.998	0.000
W07.1 Residential institution	0.002	0.998	0.000
W29.8 Other specified place	0.000	0.998	0.001
W29.6 Industrial and construction area	0.000	0.998	0.001
W29.0 Home	0.000	0.998	0.001
W29.7 Farm	0.000	0.998	0.001
W29.4 Street and highway	0.000	0.998	0.001
W29.3 Sports and athletics area	0.000	0.998	0.001
W29.2 School, other institution and public administrative area	0.000	0.998	0.001
W29.1 Residential institution	0.000	0.998	0.001
R25 Abnormal involuntary movements	0.002	0.998	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.002	0.998	0.000
M54.3 Sciatica	0.000	0.998	0.002
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Z59.7 Insufficient social insurance and welfare support	0.002	0.998	0.000
Z59.6 Low income	0.002	0.998	0.000
Z59.5 Extreme poverty	0.002	0.998	0.000
Z59.4 Lack of adequate food	0.002	0.998	0.000
Z59.3 Problems related to living in residential institution	0.002	0.998	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.000	0.998	0.002
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.998	0.000
Y50.8 Other central nervous system stimulants	0.001	0.998	0.000
Y50.1 Opioid receptor antagonists	0.001	0.998	0.000
Y50.0 Analeptics	0.001	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.002	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.998	0.002
T94.0 Sequelae of injuries involving multiple body regions	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.002	0.998	0.000
O12.0 Gestational oedema	0.002	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.998	0.002
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.998	0.002
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.002	0.998	0.000
D37.1 Stomach	0.000	0.998	0.002
F34.0 Cyclothymia	0.001	0.998	0.000
T83.2 Mechanical complication of graft of urinary organ	0.000	0.998	0.001
Z83.1 Family history of other infectious and parasitic diseases	0.000	0.998	0.002
R27 Other lack of coordination	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations