TreeWAS – Variant ID: rs6104691

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C67.9 Bladder, unspecified	0.376	0.624	0.000
C67 Malignant neoplasm of bladder	0.351	0.649	0.000
C67.3 Anterior wall of bladder	0.323	0.677	0.000
C67.2 Lateral wall of bladder	0.322	0.678	0.000
C67.5 Bladder neck	0.313	0.687	0.000
C67.8 Overlapping lesion of bladder	0.260	0.740	0.000
C67.7 Urachus	0.252	0.748	0.000
C67.0 Trigone of bladder	0.242	0.758	0.000
C67.6 Ureteric orifice	0.240	0.760	0.000
C67.1 Dome of bladder	0.235	0.765	0.000
C67.4 Posterior wall of bladder	0.224	0.776	0.000
M48.06 Spinal stenosis (Lumbar region)	0.064	0.936	0.000
C64-C68 Malignant neoplasms of urinary tract	0.048	0.952	0.000
Z96.0 Presence of urogenital implants	0.043	0.957	0.000
D41.4 Bladder	0.034	0.966	0.000
C66 Malignant neoplasm of ureter	0.033	0.967	0.000
C65 Malignant neoplasm of renal pelvis	0.031	0.969	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.031	0.969	0.000
Z96.7 Presence of other bone and tendon implants	0.025	0.975	0.000
Z96 Presence of other functional implants	0.025	0.975	0.000
C68.8 Overlapping lesion of urinary organs	0.022	0.978	0.000
C68.1 Paraurethral glands	0.022	0.978	0.000
C68.9 Urinary organ, unspecified	0.022	0.978	0.000
Z96.2 Presence of otological and audiological implants	0.021	0.979	0.000
Z96.6 Presence of orthopaedic joint implants	0.019	0.981	0.000
C68.0 Urethra	0.019	0.981	0.000
M48.0 Spinal stenosis	0.018	0.982	0.000
Z96.5 Presence of tooth-root and mandibular implants	0.018	0.982	0.000
Z96.3 Presence of artificial larynx	0.018	0.982	0.000
Z96.4 Presence of endocrine implants	0.017	0.983	0.000
R01.1 Cardiac murmur, unspecified	0.016	0.984	0.000
Z96.9 Presence of functional implant, unspecified	0.015	0.985	0.000
M48.09 Spinal stenosis (Site unspecified)	0.014	0.986	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.014	0.986	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.986	0.014
M48.05 Spinal stenosis (Thoracolumbar region)	0.013	0.987	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.013	0.987	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.013	0.987	0.000
M48.04 Spinal stenosis (Thoracic region)	0.013	0.987	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.013	0.987	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.012	0.988	0.000
Z96.1 Presence of intraocular lens	0.012	0.988	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.012	0.988	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.011	0.989	0.000
M48 Other spondylopathies	0.010	0.990	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.010	0.990	0.000
M48.8 Other specified spondylopathies	0.009	0.991	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.009	0.991	0.000
D41.1 Renal pelvis	0.009	0.991	0.000
D41.9 Urinary organ, unspecified	0.008	0.992	0.000
D41.7 Other urinary organs	0.008	0.992	0.000
D41.3 Urethra	0.008	0.992	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.008	0.992	0.000
D41.2 Ureter	0.008	0.992	0.000
K14.0 Glossitis	0.000	0.992	0.008
R01 Cardiac murmurs and other cardiac sounds	0.008	0.992	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.008	0.992	0.000
M48.4 Fatigue fracture of vertebra	0.008	0.992	0.000
M48.3 Traumatic spondylopathy	0.008	0.992	0.000
M48.2 Kissing spine	0.008	0.992	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.008	0.992	0.000
D73.0 Hyposplenism	0.008	0.992	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.008	0.992	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.008	0.992	0.000
M48.9 Spondylopathy, unspecified	0.007	0.992	0.000
M54.9 Dorsalgia, unspecified	0.008	0.992	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.007	0.993	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.007	0.993	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.007	0.993	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.007	0.993	0.000
K13.0 Diseases of lips	0.000	0.993	0.007
M48.89 Other specified spondylopathies (Site unspecified)	0.006	0.993	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.006	0.993	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.006	0.993	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.006	0.993	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.006	0.993	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.006	0.993	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.006	0.993	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.006	0.993	0.000
S72.30 Fracture of shaft of femur (closed)	0.006	0.994	0.000
R01.0 Benign and innocent cardiac murmurs	0.006	0.994	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.006	0.994	0.000
R01.2 Other cardiac sounds	0.006	0.994	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.006	0.994	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.006	0.994	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.006	0.994	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.006	0.994	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.006	0.994	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.006	0.994	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.006	0.994	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.006	0.994	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.006	0.994	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.006	0.994	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.006	0.994	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.006	0.994	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.006	0.994	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.006	0.994	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.006	0.994	0.000
M48.29 Kissing spine (Site unspecified)	0.006	0.994	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M48.27 Kissing spine (Lumbosacral region)	0.006	0.994	0.000
M48.26 Kissing spine (Lumbar region)	0.006	0.994	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.006	0.994	0.000
M48.24 Kissing spine (Thoracic region)	0.006	0.994	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.006	0.994	0.000
M48.22 Kissing spine (Cervical region)	0.006	0.994	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.006	0.994	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.006	0.994	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.006	0.994	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.006	0.994	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.006	0.994	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.006	0.994	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.006	0.994	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.006	0.994	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.006	0.994	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.006	0.994	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.006	0.994	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.006	0.994	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.006	0.994	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.006	0.994	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.006	0.994	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.006	0.994	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.006	0.994	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.006	0.994	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.006	0.994	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.006	0.994	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.006	0.994	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.005	0.994	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.005	0.994	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.005	0.994	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.005	0.994	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.005	0.994	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.005	0.994	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.005	0.994	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.005	0.994	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.006	0.994	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.006	0.994	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.005	0.994	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.006	0.994	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.006	0.994	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.005	0.994	0.000
R45.1 Restlessness and agitation	0.000	0.995	0.005
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.005	0.995	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.004	0.995	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.004	0.995	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.004	0.996	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.004	0.996	0.000
D41.0 Kidney	0.004	0.996	0.000
H83.0 Labyrinthitis	0.004	0.996	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.996	0.004
N88.2 Stricture and stenosis of cervix uteri	0.004	0.996	0.000
S71.1 Open wound of thigh	0.004	0.996	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.004	0.996	0.000
K38.9 Disease of appendix, unspecified	0.004	0.996	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.004	0.996	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.996	0.004
I08.2 Disorders of both aortic and tricuspid valves	0.004	0.996	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.004	0.996	0.000
N86 Erosion and ectropion of cervix uteri	0.000	0.996	0.004
K36 Other appendicitis	0.004	0.996	0.000
S72.3 Fracture of shaft of femur	0.004	0.996	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.004	0.996	0.000
K38 Other diseases of appendix	0.004	0.996	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.004	0.996	0.000
K38.8 Other specified diseases of appendix	0.004	0.996	0.000
M48.02 Spinal stenosis (Cervical region)	0.003	0.996	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.996	0.004
S46.0 Injury of tendon of the rotator cuff of shoulder	0.003	0.997	0.000
Z49.0 Preparatory care for dialysis	0.003	0.997	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.003	0.997	0.000
D73 Diseases of spleen	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.997	0.003
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.003	0.997	0.000
K38.1 Appendicular concretions	0.003	0.997	0.000
S72.31 Fracture of shaft of femur (open)	0.003	0.997	0.000
D73.5 Infarction of spleen	0.003	0.997	0.000
K38.3 Fistula of appendix	0.003	0.997	0.000
K38.2 Diverticulum of appendix	0.003	0.997	0.000
K38.0 Hyperplasia of appendix	0.003	0.997	0.000
Q43.8 Other specified congenital malformations of intestine	0.003	0.997	0.000
K13 Other diseases of lip and oral mucosa	0.000	0.997	0.003
M79.67 Pain in limb (Ankle and foot)	0.000	0.997	0.003
K35-K38 Diseases of appendix	0.003	0.997	0.000
O47.9 False labour, unspecified	0.000	0.997	0.003
I08.8 Other multiple valve diseases	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.000	0.997	0.003
Q82.8 Other specified congenital malformations of skin	0.000	0.997	0.003
I08 Multiple valve diseases	0.003	0.997	0.000
H74.0 Tympanosclerosis	0.003	0.997	0.000
D73.9 Disease of spleen, unspecified	0.002	0.997	0.000
D73.3 Abscess of spleen	0.002	0.997	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.997	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.997	0.003
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.003	0.997	0.000
D73.8 Other diseases of spleen	0.002	0.997	0.000
D46.7 Other myelodysplastic syndromes	0.002	0.998	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
S71 Open wound of hip and thigh	0.002	0.998	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.002	0.998	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.000	0.998	0.002
K13.5 Oral submucous fibrosis	0.000	0.998	0.002
K13.3 Hairy leukoplakia	0.000	0.998	0.002
K13.1 Cheek and lip biting	0.000	0.998	0.002
R45 Symptoms and signs involving emotional state	0.000	0.998	0.002
S46 Injury of muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.002	0.998	0.000
W55.7 Farm	0.002	0.998	0.000
D73.1 Hypersplenism	0.002	0.998	0.000
R45.0 Nervousness	0.000	0.998	0.002
D73.4 Cyst of spleen	0.002	0.998	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.000	0.998	0.002
H71 Cholesteatoma of middle ear	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.002	0.998	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.002	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.998	0.000
K35 Acute appendicitis	0.002	0.998	0.000
K02.9 Dental caries, unspecified	0.002	0.998	0.000
W55.8 Other specified place	0.002	0.998	0.000
G96 Other disorders of central nervous system	0.000	0.998	0.002
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
Z96.8 Presence of other specified functional implants	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.002	0.998	0.000
S71.7 Multiple open wounds of of hip and thigh	0.002	0.998	0.000
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
W55 Bitten or struck by other mammals	0.002	0.998	0.000
F80.1 Expressive language disorder	0.002	0.998	0.000
N13.3 Other and unspecified hydronephrosis	0.002	0.998	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.002	0.998	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.002	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.002	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.000	0.998	0.002
R45.4 Irritability and anger	0.000	0.998	0.002
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
Z49 Care involving dialysis	0.002	0.998	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.000	0.998	0.002
D46.4 Refractory anaemia, unspecified	0.002	0.998	0.000
D46.1 Refractory anaemia with sideroblasts	0.002	0.998	0.000
O26.8 Other specified pregnancy-related conditions	0.000	0.998	0.002
R45.7 State of emotional shock and stress, unspecified	0.000	0.998	0.002
R45.3 Demoralisation and apathy	0.000	0.998	0.002
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.002	0.998	0.000
W55.4 Street and highway	0.002	0.998	0.000
D43.0 Brain, supratentorial	0.002	0.998	0.000
S46.3 Injury of muscle and tendon of triceps	0.002	0.998	0.000
H83 Other diseases of inner ear	0.002	0.998	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.998	0.002
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.002	0.998	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.002	0.998	0.000
H70.9 Mastoiditis, unspecified	0.002	0.998	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
R45.6 Physical violence	0.000	0.998	0.002
R45.5 Hostility	0.000	0.998	0.002
S71.0 Open wound of hip	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.998	0.002
H70 Mastoiditis and related conditions	0.002	0.998	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.002	0.998	0.000
D43.2 Brain, unspecified	0.002	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.998	0.002
J43.9 Emphysema, unspecified	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
R45.2 Unhappiness	0.000	0.998	0.002
G96.8 Other specified disorders of central nervous system	0.000	0.998	0.002
K35.1 Acute appendicitis with peritoneal abscess	0.002	0.998	0.000
M20.0 Deformity of finger(s)	0.000	0.998	0.002
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
S72 Fracture of femur	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
G96.9 Disorder of central nervous system, unspecified	0.000	0.998	0.002
J33.8 Other polyp of sinus	0.000	0.998	0.002
T85.2 Mechanical complication of intraocular lens	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
O42 Premature rupture of membranes	0.000	0.998	0.002
H70.8 Other mastoiditis and related conditions	0.002	0.998	0.000
H70.0 Acute mastoiditis	0.002	0.998	0.000
S72.9 Fracture of femur, part unspecified	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
L53.9 Erythematous condition, unspecified	0.000	0.998	0.002
W55.9 Unspecified place	0.002	0.998	0.000
W55.5 Trade and service area	0.002	0.998	0.000
W55.6 Industrial and construction area	0.002	0.998	0.000
W55.3 Sports and athletics area	0.002	0.998	0.000
W55.2 School, other institution and public administrative area	0.002	0.998	0.000
W55.1 Residential institution	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
N41.0 Acute prostatitis	0.002	0.998	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.998	0.002
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.002	0.998	0.000
H83.3 Noise effects on inner ear	0.002	0.998	0.000
Z51.3 Blood transfusion without reported diagnosis	0.000	0.998	0.002
D43.9 Central nervous system, unspecified	0.002	0.998	0.000
D43.7 Other parts of central nervous system	0.002	0.998	0.000
D43.3 Cranial nerves	0.002	0.998	0.000
H83.2 Labyrinthine dysfunction	0.002	0.998	0.000
H83.1 Labyrinthine fistula	0.002	0.998	0.000
N94.3 Premenstrual tension syndrome	0.000	0.998	0.002
Z49.2 Other dialysis	0.002	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
K35.9 Acute appendicitis, unspecified	0.002	0.998	0.000
R85.7 Abnormal histological findings	0.002	0.998	0.000
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.998	0.002
O41.0 Oligohydramnios	0.000	0.998	0.002
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.998	0.002
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.002	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.002	0.998	0.000
D43.4 Spinal cord	0.001	0.998	0.000
H70.2 Petrositis	0.001	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
M81.9 Osteoporosis, unspecified	0.002	0.998	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.002	0.998	0.000
H83.9 Disease of inner ear, unspecified	0.001	0.998	0.000
S72.7 Multiple fractures of femur	0.001	0.998	0.000
G95.1 Vascular myelopathies	0.000	0.998	0.002
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
S72.4 Fracture of lower end of femur	0.002	0.998	0.000
D43.1 Brain, infratentorial	0.001	0.998	0.000
W55.0 Home	0.001	0.998	0.000
K37 Unspecified appendicitis	0.002	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.998	0.000
S72.91 Fracture of femur, part unspecified (open)	0.001	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.998	0.001
S64.3 Injury of digital nerve of thumb	0.002	0.998	0.000
S72.8 Fractures of other parts of femur	0.001	0.998	0.000
N41 Inflammatory diseases of prostate	0.002	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.998	0.000
W55.58 Bitten or struck by other mammals; Trade and service area;While engaged in other specified activities	0.001	0.998	0.000
W55.99 Bitten or struck by other mammals: Unspecified place: During unspecified activity	0.001	0.998	0.000
D47.4 Osteomyelofibrosis	0.001	0.998	0.000
H83.8 Other specified diseases of inner ear	0.001	0.998	0.000
K35.3 Acute appendicitis with localized peritonitis	0.001	0.998	0.000
Q43.7 Persistent cloaca	0.001	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.001	0.998	0.000
Q43.5 Ectopic anus	0.001	0.998	0.000
Q43.4 Duplication of intestine	0.001	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.001	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.001	0.998	0.000
Q43.1 Hirschsprung's disease	0.001	0.998	0.000
S72.2 Subtrochanteric fracture	0.001	0.998	0.000
Q82 Other congenital malformations of skin	0.000	0.998	0.001
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.998	0.000
E23.2 Diabetes insipidus	0.000	0.998	0.001
H70.1 Chronic mastoiditis	0.001	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.000	0.998	0.001
X10.0 Home	0.001	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.001	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.001	0.998	0.000
N41.2 Abscess of prostate	0.001	0.998	0.000
R47.8 Other and unspecified speech disturbances	0.002	0.998	0.000
M60.96 Myositis, unspecified (Lower leg)	0.001	0.999	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.001	0.999	0.000
M06.0 Seronegative rheumatoid arthritis	0.001	0.999	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.001	0.999	0.000
L53.8 Other specified erythematous conditions	0.000	0.999	0.001
M94.8 Other specified disorders of cartilage	0.001	0.999	0.000
N13.4 Hydroureter	0.001	0.999	0.000
N80.3 Endometriosis of pelvic peritoneum	0.000	0.999	0.001
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.001	0.999	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.001	0.999	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H67 Otitis media in diseases classified elsewhere	0.001	0.999	0.000
M60.05 Infective myositis (Pelvic region and thigh)	0.001	0.999	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
D42.9 Meninges, unspecified	0.001	0.999	0.000
D42.1 Spinal meninges	0.001	0.999	0.000
D42.0 Cerebral meninges	0.001	0.999	0.000
N41.8 Other inflammatory diseases of prostate	0.001	0.999	0.000
R85.5 Abnormal microbiological findings	0.001	0.999	0.000
H69 Other disorders of Eustachian tube	0.001	0.999	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.001	0.999	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.001	0.999	0.000
M94.88 Other specified disorders of cartilage (Other)	0.001	0.999	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.001	0.999	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.999	0.001
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.999	0.001
M19.94 Arthrosis, unspecified (Hand)	0.000	0.999	0.001
M81.93 Osteoporosis, unspecified (Forearm)	0.001	0.999	0.000
S72.41 Fracture of lower end of femur (open)	0.001	0.999	0.000
S72.71 Multiple fractures of femur (open)	0.001	0.999	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.999	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.001	0.999	0.000
T51.9 Alcohol, unspecified	0.000	0.999	0.001
W06.0 Home	0.000	0.999	0.001
H68 Eustachian salpingitis and obstruction	0.001	0.999	0.000
S70-S79 Injuries to the hip and thigh	0.001	0.999	0.000
O23.5 Infections of the genital tract in pregnancy	0.000	0.999	0.001
T51.0 Ethanol	0.000	0.999	0.001
M94.26 Chondromalacia (Lower leg)	0.001	0.999	0.000
S72.81 Fractures of other parts of femur (open)	0.001	0.999	0.000
N41.3 Prostatocystitis	0.001	0.999	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.001	0.999	0.000
S72.21 Subtrochanteric fracture (open)	0.001	0.999	0.000
D38.1 Trachea, bronchus and lung	0.001	0.999	0.000
D44.7 Aortic body and other paraganglia	0.001	0.999	0.000
Q82.9 Congenital malformation of skin, unspecified	0.000	0.999	0.001
Q82.4 Ectodermal dysplasia (anhidrotic)	0.000	0.999	0.001
Q82.3 Incontinentia pigmenti	0.000	0.999	0.001
Q82.1 Xeroderma pigmentosum	0.000	0.999	0.001
H73 Other disorders of tympanic membrane	0.001	0.999	0.000
S32.50 Fracture of pubis (closed)	0.000	0.999	0.001
D38.6 Respiratory organ, unspecified	0.001	0.999	0.000
D38.4 Thymus	0.001	0.999	0.000
D38.3 Mediastinum	0.001	0.999	0.000
D38.2 Pleura	0.001	0.999	0.000
H66.4 Suppurative otitis media, unspecified	0.001	0.999	0.000
M94.2 Chondromalacia	0.001	0.999	0.000
R85.9 Unspecified abnormal finding	0.001	0.999	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.001	0.999	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.001	0.999	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.001	0.999	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.001	0.999	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.001	0.999	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.001	0.999	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.001	0.999	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.001	0.999	0.000
M60.9 Myositis, unspecified	0.001	0.999	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.000	0.999	0.001
M92 Other juvenile osteochondrosis	0.001	0.999	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.001	0.999	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.999	0.001
M94.84 Other specified disorders of cartilage (Hand)	0.001	0.999	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.001	0.999	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.001	0.999	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.001	0.999	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.001	0.999	0.000
D40.9 Male genital organ, unspecified	0.001	0.999	0.000
D40.7 Other male genital organs	0.001	0.999	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.001	0.999	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.001	0.999	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.001	0.999	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
M92.2 Juvenile osteochondrosis of hand	0.001	0.999	0.000
Q82.0 Hereditary lymphoedema	0.000	0.999	0.001
J40 Bronchitis, not specified as acute or chronic	0.000	0.999	0.001
M94 Other disorders of cartilage	0.001	0.999	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.001	0.999	0.000
S72.40 Fracture of lower end of femur (closed)	0.001	0.999	0.000
S72.80 Fractures of other parts of femur (closed)	0.001	0.999	0.000
H69.0 Patulous Eustachian tube	0.001	0.999	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.001	0.999	0.000
M60.95 Myositis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.001	0.999	0.000
H68.0 Eustachian salpingitis	0.001	0.999	0.000
M60.0 Infective myositis	0.001	0.999	0.000
Q54.9 Hypospadias, unspecified	0.001	0.999	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.001	0.999	0.000
S78 Traumatic amputation of hip and thigh	0.001	0.999	0.000
S77 Crushing injury of hip and thigh	0.001	0.999	0.000
S75 Injury of blood vessels at hip and thigh level	0.001	0.999	0.000
S74 Injury of nerves at hip and thigh level	0.001	0.999	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.001	0.999	0.000
D38.5 Other respiratory organs	0.001	0.999	0.000
D40.1 Testis	0.001	0.999	0.000
D44.6 Carotid body	0.001	0.999	0.000
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
H69.8 Other specified disorders of Eustachian tube	0.001	0.999	0.000
D45 Polycythaemia vera	0.001	0.999	0.000
H66 Suppurative and unspecified otitis media	0.001	0.999	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.001	0.999	0.000
S72.20 Subtrochanteric fracture (closed)	0.001	0.999	0.000
H73.1 Chronic myringitis	0.001	0.999	0.000
H73.0 Acute myringitis	0.001	0.999	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.001	0.999	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.999	0.001
Q82.2 Mastocytosis	0.000	0.999	0.001
Y43.4 Immunosuppressive agents	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations