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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61740470
log Bayes Factor = 25.1179
Chromosome 3   position 46,491,985  (GRCh37) Explore rs61740470 on Ensembl!
Variant rs61740470 is part of Cluster X0253

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
R50-R69 General symptoms and signs
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.990 0.010 0.000
Z86 Personal history of certain other diseases
0.990 0.010 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.989 0.011 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.986 0.014 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.983 0.017 0.000
Z95.1 Presence of aortocoronary bypass graft
0.983 0.017 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.982 0.018 0.000
Z92 Personal history of medical treatment
0.980 0.020 0.000
O60-O75 Complications of labour and delivery
0.979 0.021 0.000
E10-E14 Diabetes mellitus
0.974 0.026 0.000
I50 Heart failure
0.973 0.027 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.971 0.029 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.970 0.030 0.000
R55 Syncope and collapse
0.968 0.032 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.967 0.033 0.000
Chapter V Mental and behavioural disorders
0.963 0.037 0.000
E78.0 Pure hypercholesterolaemia
0.953 0.047 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.941 0.059 0.000
I50.1 Left ventricular failure
0.940 0.060 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.940 0.060 0.000
R20 Disturbances of skin sensation
0.939 0.061 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.938 0.062 0.000
Z13 Special screening examination for other diseases and disorders
0.933 0.067 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.932 0.068 0.000
I67 Other cerebrovascular diseases
0.932 0.068 0.000
E87.6 Hypokalaemia
0.931 0.069 0.000
Z88.6 Personal history of allergy to analgesic agent
0.930 0.070 0.000
Chapter XX External causes of morbidity and mortality
0.924 0.076 0.000
R53 Malaise and fatigue
0.923 0.077 0.000
G90-G99 Other disorders of the nervous system
0.918 0.081 0.000
Z13.9 Special screening examination, unspecified
0.916 0.084 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.915 0.085 0.000
Z95.0 Presence of cardiac pacemaker
0.914 0.086 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.913 0.087 0.000
E11 Non-insulin-dependent diabetes mellitus
0.912 0.088 0.000
E87.2 Acidosis
0.909 0.091 0.000
I42 Cardiomyopathy
0.909 0.091 0.000
I73 Other peripheral vascular diseases
0.906 0.094 0.000
Z95.4 Presence of other heart-valve replacement
0.905 0.095 0.000
I63 Cerebral infarction
0.903 0.097 0.000
Chapter XIV Diseases of the genitourinary system
0.900 0.100 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.898 0.102 0.000
I20-I25 Ischaemic heart diseases
0.897 0.103 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.893 0.107 0.000
E86 Volume depletion
0.890 0.110 0.000
I69 Sequelae of cerebrovascular disease
0.890 0.110 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.889 0.111 0.000
Z86.4 Personal history of psychoactive substance abuse
0.889 0.111 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.888 0.112 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.888 0.112 0.000
Z89 Acquired absence of limb
0.879 0.121 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.878 0.122 0.000
Z93 Artificial opening status
0.877 0.123 0.000
N17-N19 Renal failure
0.877 0.123 0.000
I46 Cardiac arrest
0.875 0.125 0.000
Z86.7 Personal history of diseases of the circulatory system
0.872 0.128 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.872 0.128 0.000
E11.3 With ophthalmic complications
0.871 0.129 0.000
E14 Unspecified diabetes mellitus
0.869 0.131 0.000
T81 Complications of procedures, not elsewhere classified
0.868 0.132 0.000
E87.0 Hyperosmolality and hypernatraemia
0.867 0.133 0.000
R59 Enlarged lymph nodes
0.861 0.139 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.860 0.140 0.000
I67.1 Cerebral aneurysm, nonruptured
0.859 0.141 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.859 0.141 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.854 0.146 0.000
I73.9 Peripheral vascular disease, unspecified
0.854 0.146 0.000
R52 Pain, not elsewhere classified
0.853 0.147 0.000
Chapter XI Diseases of the digestive system
0.853 0.147 0.000
R21 Rash and other nonspecific skin eruption
0.850 0.150 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.848 0.151 0.000
O70 Perineal laceration during delivery
0.848 0.152 0.000
I33 Acute and subacute endocarditis
0.847 0.153 0.000
I38 Endocarditis, valve unspecified
0.847 0.153 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.847 0.153 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.846 0.154 0.000
Z88.5 Personal history of allergy to narcotic agent
0.845 0.155 0.000
G81 Hemiplegia
0.845 0.155 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.839 0.161 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.838 0.162 0.000
R20.2 Paraesthesia of skin
0.838 0.162 0.000
Chapter VIII Diseases of the ear and mastoid process
0.837 0.163 0.000
Chapter I Certain infectious and parasitic diseases
0.837 0.163 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.837 0.163 0.000
Z95.2 Presence of prosthetic heart valve
0.833 0.167 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.833 0.167 0.000
Z13.1 Special screening examination for diabetes mellitus
0.829 0.171 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.829 0.171 0.000
I35 Nonrheumatic aortic valve disorders
0.827 0.173 0.000
Z80 Family history of malignant neoplasm
0.823 0.177 0.000
G30-G32 Other degenerative diseases of the nervous system
0.819 0.181 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.817 0.183 0.000
F03 Unspecified dementia
0.816 0.184 0.000
S00-S09 Injuries to the head
0.816 0.184 0.000
O63 Long labour
0.816 0.184 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.815 0.185 0.000
R61 Hyperhidrosis
0.814 0.186 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.814 0.186 0.000
I51 Complications and ill-defined descriptions of heart disease
0.812 0.188 0.000
M50-M54 Other dorsopathies
0.812 0.188 0.000
E00-E07 Disorders of thyroid gland
0.808 0.192 0.000
G93 Other disorders of brain
0.808 0.192 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.807 0.193 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.807 0.193 0.000
I20 Angina pectoris
0.806 0.194 0.000
N10-N16 Renal tubulo-interstitial diseases
0.805 0.195 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.804 0.196 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.803 0.197 0.000
N17 Acute renal failure
0.801 0.199 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.800 0.200 0.000
E87.5 Hyperkalaemia
0.799 0.201 0.000
E20-E35 Disorders of other endocrine glands
0.799 0.201 0.000
K90-K93 Other diseases of the digestive system
0.799 0.201 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.799 0.201 0.000
D50-D53 Nutritional anaemias
0.798 0.202 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.797 0.203 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.796 0.204 0.000
G81.9 Hemiplegia, unspecified
0.795 0.205 0.000
Z45 Adjustment and management of implanted device
0.794 0.206 0.000
Z93.3 Colostomy status
0.794 0.206 0.000
I05-I09 Chronic rheumatic heart diseases
0.793 0.207 0.000
R29.6 Tendency to fall, not elsewhere classified
0.792 0.208 0.000
I60 Subarachnoid haemorrhage
0.790 0.210 0.000
M45-M49 Spondylopathies
0.790 0.210 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.789 0.211 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.789 0.211 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.788 0.212 0.000
Z51 Other medical care
0.788 0.212 0.000
I46.0 Cardiac arrest with successful resuscitation
0.787 0.213 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.786 0.214 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.786 0.214 0.000
S60-S69 Injuries to the wrist and hand
0.786 0.214 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.785 0.215 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.785 0.215 0.000
I70 Atherosclerosis
0.784 0.216 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.783 0.217 0.000
I42.9 Cardiomyopathy, unspecified
0.782 0.218 0.000
E50-E64 Other nutritional deficiencies
0.782 0.218 0.000
Z50 Care involving use of rehabilitation procedures
0.782 0.218 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.781 0.219 0.000
I47 Paroxysmal tachycardia
0.781 0.219 0.000
Z95.3 Presence of xenogenic heart valve
0.780 0.220 0.000
Z86.0 Personal history of other neoplasms
0.780 0.220 0.000
S40-S49 Injuries to the shoulder and upper arm
0.778 0.222 0.000
R63 Symptoms and signs concerning food and fluid intake
0.778 0.222 0.000
I42.0 Dilated cardiomyopathy
0.778 0.222 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.776 0.224 0.000
E13 Other specified diabetes mellitus
0.774 0.225 0.000
M05-M14 Inflammatory polyarthropathies
0.774 0.226 0.000
K31 Other diseases of stomach and duodenum
0.774 0.226 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.773 0.227 0.000
I50.0 Congestive heart failure
0.772 0.228 0.000
N19 Unspecified renal failure
0.772 0.228 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.771 0.229 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.771 0.229 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.771 0.229 0.000
G20-G26 Extrapyramidal and movement disorders
0.771 0.229 0.000
R47-R49 Symptoms and signs involving speech and voice
0.770 0.230 0.000
Z51.2 Other chemotherapy
0.768 0.232 0.000
F99-F99 Unspecified mental disorder
0.766 0.234 0.000
R26 Abnormalities of gait and mobility
0.763 0.236 0.000
E14.9 Without complications
0.762 0.238 0.000
R52.1 Chronic intractable pain
0.761 0.238 0.000
K31.7 Polyp of stomach and duodenum
0.761 0.239 0.000
I61 Intracerebral haemorrhage
0.756 0.244 0.000
Z92.3 Personal history of irradiation
0.754 0.246 0.000
I50.9 Heart failure, unspecified
0.754 0.246 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.753 0.247 0.000
I67.9 Cerebrovascular disease, unspecified
0.753 0.247 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.752 0.248 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.750 0.249 0.000
E83 Disorders of mineral metabolism
0.750 0.250 0.000
I77 Other disorders of arteries and arterioles
0.750 0.250 0.000
K92 Other diseases of digestive system
0.750 0.250 0.000
I74 Arterial embolism and thrombosis
0.749 0.251 0.000
N17.9 Acute renal failure, unspecified
0.748 0.252 0.000
R59.0 Localised enlarged lymph nodes
0.747 0.253 0.000
T86 Failure and rejection of transplanted organs and tissues
0.747 0.253 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.747 0.253 0.000
I63.9 Cerebral infarction, unspecified
0.747 0.253 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.747 0.253 0.000
N18 Chronic renal failure
0.745 0.255 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.744 0.256 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.743 0.257 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.743 0.257 0.000
I78 Diseases of capillaries
0.742 0.258 0.000
R50 Fever of unknown origin
0.742 0.258 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.740 0.260 0.000
I33.0 Acute and subacute infective endocarditis
0.739 0.261 0.000
N13 Obstructive and reflux uropathy
0.738 0.262 0.000
R60 Oedema, not elsewhere classified
0.737 0.262 0.000
D80-D89 Certain disorders involving the immune mechanism
0.737 0.263 0.000
B35-B49 Mycoses
0.736 0.264 0.000
Z89.6 Acquired absence of leg above knee
0.734 0.266 0.000
D50 Iron deficiency anaemia
0.733 0.267 0.000
E88 Other metabolic disorders
0.733 0.267 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.732 0.268 0.000
O70.0 First degree perineal laceration during delivery
0.731 0.269 0.000
E04 Other non-toxic goitre
0.730 0.270 0.000
Z89.4 Acquired absence of foot and ankle
0.730 0.270 0.000
F30-F39 Mood [affective] disorders
0.730 0.270 0.000
Y43 Primarily systemic agents
0.729 0.271 0.000
Z94 Transplanted organ and tissue status
0.729 0.271 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.728 0.272 0.000
Z48 Other surgical follow-up care
0.728 0.272 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.728 0.272 0.000
M51 Other intervertebral disk disorders
0.725 0.275 0.000
M86-M90 Other osteopathies
0.725 0.275 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.724 0.276 0.000
T79-T79 Certain early complications of trauma
0.724 0.276 0.000
Z40 Prophylactic surgery
0.724 0.276 0.000
N30-N39 Other diseases of urinary system
0.724 0.276 0.000
Z97 Presence of other devices
0.723 0.277 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.722 0.278 0.000
O42 Premature rupture of membranes
0.721 0.279 0.000
S50-S59 Injuries to the elbow and forearm
0.720 0.280 0.000
Chapter II Neoplasms
0.720 0.280 0.000
I34 Nonrheumatic mitral valve disorders
0.719 0.281 0.000
I49 Other cardiac arrhythmias
0.719 0.281 0.000
O72 Postpartum haemorrhage
0.719 0.281 0.000
K30 Dyspepsia
0.718 0.282 0.000
K92.1 Melaena
0.718 0.282 0.000
I35.0 Aortic (valve) stenosis
0.718 0.282 0.000
O80-O84 Delivery
0.717 0.282 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.717 0.283 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
S70-S79 Injuries to the hip and thigh
0.716 0.284 0.000
O48 Prolonged pregnancy
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.715 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.715 0.284 0.000
I62 Other nontraumatic intracranial haemorrhage
0.715 0.284 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.715 0.285 0.000
R68 Other general symptoms and signs
0.715 0.285 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.715 0.285 0.000
R62 Lack of expected normal physiological development
0.715 0.285 0.000
R57 Shock, not elsewhere classified
0.715 0.285 0.000
R64 Cachexia
0.715 0.285 0.000
R58 Haemorrhage, not elsewhere classified
0.715 0.285 0.000
G83 Other paralytic syndromes
0.715 0.285 0.000
G40-G47 Episodic and paroxysmal disorders
0.714 0.286 0.000
Z35 Supervision of high-risk pregnancy
0.713 0.287 0.000
G91 Hydrocephalus
0.713 0.287 0.000
O85-O92 Complications predominantly related to the puerperium
0.713 0.287 0.000
D60-D64 Aplastic and other anaemias
0.713 0.287 0.000
G95 Other diseases of spinal cord
0.712 0.288 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.711 0.289 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.710 0.290 0.000
Z04 Examination and observation for other reasons
0.709 0.290 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.709 0.291 0.000
E87.4 Mixed disorder of acid-base balance
0.709 0.291 0.000
E87.3 Alkalosis
0.709 0.291 0.000
T66-T78 Other and unspecified effects of external causes
0.709 0.291 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.708 0.292 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.707 0.293 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.707 0.293 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.707 0.293 0.000
F00 Dementia in Alzheimer's disease
0.705 0.294 0.000
G96 Other disorders of central nervous system
0.705 0.295 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.705 0.295 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.705 0.295 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.705 0.295 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.705 0.295 0.000
T00-T07 Injuries involving multiple body regions
0.705 0.295 0.000
S10-S19 Injuries to the neck
0.705 0.295 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.704 0.296 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.704 0.296 0.000
R23 Other skin changes
0.704 0.296 0.000
R63.1 Polydipsia
0.704 0.296 0.000
Z34 Supervision of normal pregnancy
0.703 0.297 0.000
Z01.6 Radiological examination, not elsewhere classified
0.702 0.298 0.000
Z92.9 Personal history of medical treatment, unspecified
0.702 0.298 0.000
Z92.8 Personal history of other medical treatment
0.702 0.298 0.000
Z92.5 Personal history of rehabilitation measures
0.702 0.298 0.000
Z92.0 Personal history of contraception
0.702 0.298 0.000
O74 Complications of anaesthesia during labour and delivery
0.702 0.298 0.000
O73 Retained placenta and membranes, without haemorrhage
0.702 0.298 0.000
O71 Other obstetric trauma
0.702 0.298 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.702 0.298 0.000
O66 Other obstructed labour
0.702 0.298 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.702 0.298 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.702 0.298 0.000
O62 Abnormalities of forces of labour
0.702 0.298 0.000
O61 Failed induction of labour
0.702 0.298 0.000
O60 Preterm delivery
0.702 0.298 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.701 0.299 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.700 0.300 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.699 0.301 0.000
E12 Malnutrition-related diabetes mellitus
0.699 0.301 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.698 0.302 0.000
M50 Cervical disk disorders
0.697 0.302 0.000
S90-S99 Injuries to the ankle and foot
0.697 0.303 0.000
I67.2 Cerebral atherosclerosis
0.697 0.303 0.000
Z83 Family history of other specific disorders
0.696 0.304 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.696 0.304 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.695 0.305 0.000
E78.8 Other disorders of lipoprotein metabolism
0.695 0.305 0.000
E78.6 Lipoprotein deficiency
0.695 0.305 0.000
E78.4 Other hyperlipidaemia
0.695 0.305 0.000
E78.3 Hyperchylomicronaemia
0.695 0.305 0.000
E78.2 Mixed hyperlipidaemia
0.695 0.305 0.000
E78.1 Pure hyperglyceridaemia
0.695 0.305 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.695 0.305 0.000
X60-X84 Intentional self-harm
0.694 0.306 0.000
E14.3 With ophthalmic complications
0.694 0.306 0.000
R25 Abnormal involuntary movements
0.694 0.306 0.000
N25-N29 Other disorders of kidney and ureter
0.693 0.306 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.693 0.307 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.693 0.307 0.000
I72 Other aneurysm
0.693 0.307 0.000
R69 Unknown and unspecified causes of morbidity
0.692 0.308 0.000
I73.0 Raynaud's syndrome
0.692 0.308 0.000
M48 Other spondylopathies
0.691 0.309 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.690 0.309 0.000
F80-F89 Disorders of psychological development
0.690 0.309 0.000
F70-F79 Mental retardation
0.690 0.309 0.000
F60-F69 Disorders of adult personality and behaviour
0.690 0.309 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.690 0.309 0.000
S80-S89 Injuries to the knee and lower leg
0.690 0.310 0.000
G30 Alzheimer's disease
0.689 0.311 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.688 0.312 0.000
O63.1 Prolonged second stage (of labour)
0.688 0.312 0.000
R94 Abnormal results of function studies
0.687 0.312 0.000
I47.2 Ventricular tachycardia
0.687 0.313 0.000
I21 Acute myocardial infarction
0.687 0.313 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.686 0.314 0.000
N39 Other disorders of urinary system
0.686 0.314 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.685 0.315 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.685 0.315 0.000
G93.9 Disorder of brain, unspecified
0.685 0.315 0.000
E87.7 Fluid overload
0.684 0.316 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.684 0.316 0.000
R61.9 Hyperhidrosis, unspecified
0.683 0.317 0.000
V10-V19 Pedal cyclist injured in transport accident
0.683 0.317 0.000
E10 Insulin-dependent diabetes mellitus
0.683 0.317 0.000
N39.0 Urinary tract infection, site not specified
0.682 0.318 0.000
Z88.2 Personal history of allergy to sulphonamides
0.681 0.318 0.000
N13.3 Other and unspecified hydronephrosis
0.681 0.318 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.681 0.319 0.000
W20-W49 Exposure to inanimate mechanical forces
0.681 0.319 0.000
G25 Other extrapyramidal and movement disorders
0.679 0.321 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.679 0.321 0.000
S20-S29 Injuries to the thorax
0.678 0.322 0.000
Z50.8 Care involving use of rehabilitation procedures
0.677 0.323 0.000
G61 Inflammatory polyneuropathy
0.676 0.324 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.675 0.325 0.000
Z10 Routine general health check-up of defined subpopulation
0.675 0.325 0.000
T87 Complications peculiar to reattachment and amputation
0.674 0.326 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.674 0.326 0.000
R20.3 Hyperaesthesia
0.673 0.326 0.000
R20.1 Hypoaesthesia of skin
0.673 0.326 0.000
R20.0 Anaesthesia of skin
0.673 0.326 0.000
I20.0 Unstable angina
0.672 0.328 0.000
Z43 Attention to artificial openings
0.672 0.328 0.000
I22 Subsequent myocardial infarction
0.671 0.329 0.000
E04.2 Non-toxic multinodular goitre
0.669 0.331 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.669 0.331 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.669 0.331 0.000
Z13.5 Special screening examination for eye and ear disorders
0.669 0.331 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.669 0.331 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.669 0.331 0.000
Z13.2 Special screening examination for nutritional disorders
0.669 0.331 0.000
R27 Other lack of coordination
0.668 0.332 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.668 0.332 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.668 0.332 0.000
I67.5 Moyamoya disease
0.668 0.332 0.000
I67.4 Hypertensive encephalopathy
0.668 0.332 0.000
I67.3 Progressive vascular leukoencephalopathy
0.668 0.332 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.668 0.332 0.000
N99-N99 Other disorders of the genitourinary system
0.668 0.332 0.000
I31 Other diseases of pericardium
0.667 0.333 0.000
H65-H75 Diseases of middle ear and mastoid
0.667 0.333 0.000
E11.5 With peripheral circulatory complications
0.666 0.334 0.000
K83 Other diseases of biliary tract
0.665 0.335 0.000
K65-K67 Diseases of peritoneum
0.665 0.335 0.000
O75.0 Maternal distress during labour and delivery
0.664 0.335 0.000
B37 Candidiasis
0.664 0.336 0.000
M05 Seropositive rheumatoid arthritis
0.664 0.336 0.000
Z93.2 Ileostomy status
0.664 0.336 0.000
G93.6 Cerebral oedema
0.663 0.337 0.000
Z98 Other postsurgical states
0.663 0.337 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.662 0.338 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.662 0.338 0.000
Y35-Y36 Legal intervention and operations of war
0.662 0.338 0.000
Y10-Y34 Event of undetermined intent
0.662 0.338 0.000
Y00-Y09 Assault
0.662 0.338 0.000
X85-X99 Assault
0.662 0.338 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.662 0.338 0.000
X50-X57 Overexertion, travel and privation
0.662 0.338 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.662 0.338 0.000
X30-X39 Exposure to forces of nature
0.662 0.338 0.000
X20-X29 Contact with venomous animals and plants
0.662 0.338 0.000
X10-X19 Contact with heat and hot substances
0.662 0.338 0.000
X00-X09 Exposure to smoke, fire and flames
0.662 0.338 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.662 0.338 0.000
W75-W84 Other accidental threats to breathing
0.662 0.338 0.000
W65-W74 Accidental drowning and submersion
0.662 0.338 0.000
W50-W64 Exposure to animate mechanical forces
0.662 0.338 0.000
V98-V99 Other and unspecified transport accidents
0.662 0.338 0.000
V95-V97 Air and space transport accidents
0.662 0.338 0.000
V90-V94 Water transport accidents
0.662 0.338 0.000
V80-V89 Other land transport accidents
0.662 0.338 0.000
V70-V79 Bus occupant injured in transport accident
0.662 0.338 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.662 0.338 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.662 0.338 0.000
V40-V49 Car occupant injured in transport accident
0.662 0.338 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.662 0.338 0.000
V20-V29 Motorcycle rider injured in transport accident
0.662 0.338 0.000
V01-V09 Pedestrian injured in transport accident
0.662 0.338 0.000
A30-A49 Other bacterial diseases
0.662 0.338 0.000
I71 Aortic aneurysm and dissection
0.662 0.338 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.661 0.338 0.000
I83 Varicose veins of lower extremities
0.660 0.340 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.660 0.340 0.000
Z71.8 Other specified counselling
0.660 0.340 0.000
R54 Senility
0.659 0.341 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.658 0.341 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.658 0.341 0.000
G90 Disorders of autonomic nervous system
0.658 0.341 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.658 0.341 0.000
G92 Toxic encephalopathy
0.658 0.341 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.658 0.342 0.000
H80-H83 Diseases of inner ear
0.658 0.342 0.000
Z75 Problems related to medical facilities and other health care
0.657 0.343 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.657 0.343 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.657 0.343 0.000
I20.9 Angina pectoris, unspecified
0.657 0.343 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.657 0.343 0.000
G82 Paraplegia and tetraplegia
0.656 0.344 0.000
G80 Infantile cerebral palsy
0.656 0.344 0.000
R51 Headache
0.656 0.344 0.000
I51.9 Heart disease, unspecified
0.655 0.345 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.655 0.345 0.000
D55-D59 Haemolytic anaemias
0.655 0.345 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.655 0.345 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.655 0.345 0.000
O70.1 Second degree perineal laceration during delivery
0.654 0.346 0.000
M65-M68 Disorders of synovium and tendon
0.654 0.346 0.000
E11.8 With unspecified complications
0.654 0.346 0.000
E11.7 With multiple complications
0.654 0.346 0.000
E11.6 With other specified complications
0.654 0.346 0.000
E11.2 With renal complications
0.654 0.346 0.000
E11.1 With ketoacidosis
0.654 0.346 0.000
E11.0 With coma
0.654 0.346 0.000
Z37 Outcome of delivery
0.654 0.346 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.653 0.347 0.000
I20.1 Angina pectoris with documented spasm
0.652 0.348 0.000
I42.8 Other cardiomyopathies
0.652 0.348 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.652 0.348 0.000
I42.6 Alcoholic cardiomyopathy
0.652 0.348 0.000
I42.5 Other restrictive cardiomyopathy
0.652 0.348 0.000
I42.4 Endocardial fibroelastosis
0.652 0.348 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.652 0.348 0.000
I42.2 Other hypertrophic cardiomyopathy
0.652 0.348 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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