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Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61756411
log Bayes Factor = 14.7561
Chromosome 4   position 76,809,396  (GRCh37) Explore rs61756411 on Ensembl!
Variant rs61756411 is part of Cluster X0049

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.997 0.003 0.000
E10-E14 Diabetes mellitus
0.994 0.006 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.992 0.008 0.000
Chapter II Neoplasms
0.992 0.008 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.992 0.008 0.000
Chapter XXI Factors influencing health status and contact with health services
0.991 0.009 0.000
H30-H36 Disorders of choroid and retina
0.991 0.009 0.000
E70-E90 Metabolic disorders
0.981 0.019 0.000
I30-I52 Other forms of heart disease
0.979 0.021 0.000
H25-H28 Disorders of lens
0.979 0.021 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.972 0.028 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.966 0.034 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.964 0.036 0.000
I25.1 Atherosclerotic heart disease
0.963 0.037 0.000
H25 Senile cataract
0.963 0.037 0.000
Z96 Presence of other functional implants
0.963 0.037 0.000
E10 Insulin-dependent diabetes mellitus
0.960 0.040 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.959 0.041 0.000
S00-S09 Injuries to the head
0.958 0.042 0.000
Chapter V Mental and behavioural disorders
0.957 0.043 0.000
H53-H54 Visual disturbances and blindness
0.956 0.044 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.955 0.045 0.000
Z96.1 Presence of intraocular lens
0.953 0.047 0.000
H35 Other retinal disorders
0.950 0.050 0.000
C15-C26 Malignant neoplasms of digestive organs
0.943 0.057 0.000
E11 Non-insulin-dependent diabetes mellitus
0.941 0.059 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.938 0.062 0.000
I60-I69 Cerebrovascular diseases
0.936 0.064 0.000
H40-H42 Glaucoma
0.936 0.064 0.000
Z98 Other postsurgical states
0.935 0.065 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.935 0.065 0.000
H25.1 Senile nuclear cataract
0.928 0.072 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.926 0.074 0.000
I63 Cerebral infarction
0.920 0.080 0.000
H33 Retinal detachments and breaks
0.916 0.084 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.916 0.084 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.915 0.085 0.000
Z95.2 Presence of prosthetic heart valve
0.914 0.086 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.914 0.086 0.000
H35.3 Degeneration of macula and posterior pole
0.909 0.091 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.907 0.093 0.000
I63.9 Cerebral infarction, unspecified
0.900 0.100 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.897 0.103 0.000
I20 Angina pectoris
0.894 0.106 0.000
I31 Other diseases of pericardium
0.892 0.108 0.000
E78.5 Hyperlipidaemia, unspecified
0.890 0.110 0.000
H40 Glaucoma
0.890 0.110 0.000
H53 Visual disturbances
0.890 0.110 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.887 0.113 0.000
I77 Other disorders of arteries and arterioles
0.883 0.117 0.000
D00-D09 In situ neoplasms
0.883 0.117 0.000
H25.0 Senile incipient cataract
0.880 0.120 0.000
D45 Polycythaemia vera
0.878 0.122 0.000
Z82.3 Family history of stroke
0.876 0.124 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.875 0.125 0.000
Z94 Transplanted organ and tissue status
0.874 0.126 0.000
Z93 Artificial opening status
0.873 0.127 0.000
Z95.3 Presence of xenogenic heart valve
0.870 0.130 0.000
H52 Disorders of refraction and accommodation
0.865 0.135 0.000
F99-F99 Unspecified mental disorder
0.863 0.137 0.000
I44 Atrioventricular and left bundle-branch block
0.861 0.139 0.000
C20 Malignant neoplasm of rectum
0.861 0.139 0.000
E10.3 With ophthalmic complications
0.858 0.142 0.000
I24 Other acute ischaemic heart diseases
0.856 0.144 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.855 0.145 0.000
I25.2 Old myocardial infarction
0.852 0.148 0.000
S09 Other and unspecified injuries of head
0.850 0.150 0.000
E87.6 Hypokalaemia
0.848 0.152 0.000
H43-H45 Disorders of vitreous body and globe
0.848 0.152 0.000
S70-S79 Injuries to the hip and thigh
0.848 0.152 0.000
Z98.1 Arthrodesis status
0.845 0.155 0.000
H53.8 Other visual disturbances
0.843 0.157 0.000
E11.5 With peripheral circulatory complications
0.843 0.157 0.000
Chapter I Certain infectious and parasitic diseases
0.840 0.160 0.000
I25.3 Aneurysm of heart
0.840 0.160 0.000
I71 Aortic aneurysm and dissection
0.836 0.164 0.000
E10.9 Without complications
0.835 0.165 0.000
C18 Malignant neoplasm of colon
0.834 0.166 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.833 0.167 0.000
H55-H59 Other disorders of eye and adnexa
0.833 0.167 0.000
E14 Unspecified diabetes mellitus
0.829 0.171 0.000
H54 Blindness and low vision
0.825 0.175 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.824 0.176 0.000
Z96.0 Presence of urogenital implants
0.821 0.179 0.000
I49 Other cardiac arrhythmias
0.821 0.179 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.816 0.184 0.000
I47 Paroxysmal tachycardia
0.816 0.184 0.000
H36 Retinal disorders in diseases classified elsewhere
0.815 0.185 0.000
I77.1 Stricture of artery
0.815 0.185 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.815 0.185 0.000
I31.9 Disease of pericardium, unspecified
0.814 0.186 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.811 0.189 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.810 0.190 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.808 0.192 0.000
I35 Nonrheumatic aortic valve disorders
0.806 0.194 0.000
H25.8 Other senile cataract
0.803 0.197 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.802 0.198 0.000
I70 Atherosclerosis
0.801 0.199 0.000
E10.4 With neurological complications
0.801 0.199 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.800 0.200 0.000
H52.1 Myopia
0.799 0.201 0.000
Z95.0 Presence of cardiac pacemaker
0.798 0.202 0.000
Z98.0 Intestinal bypass and anastomosis status
0.797 0.203 0.000
F99 Mental disorder, not otherwise specified
0.795 0.205 0.000
S06 Intracranial injury
0.795 0.205 0.000
H53.0 Amblyopia ex anopsia
0.794 0.206 0.000
S90-S99 Injuries to the ankle and foot
0.794 0.206 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.793 0.207 0.000
S00 Superficial injury of head
0.793 0.207 0.000
Z94.0 Kidney transplant status
0.792 0.208 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.792 0.208 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.789 0.211 0.000
D04 Carcinoma in situ of skin
0.789 0.211 0.000
I42 Cardiomyopathy
0.788 0.212 0.000
H33.0 Retinal detachment with retinal break
0.784 0.215 0.000
E11.9 Without complications
0.784 0.216 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.784 0.216 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.783 0.217 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.783 0.217 0.000
Chapter XXII Codes for special purposes
0.783 0.217 0.000
I46 Cardiac arrest
0.783 0.217 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.782 0.218 0.000
I30 Acute pericarditis
0.780 0.220 0.000
C51-C58 Malignant neoplasms of female genital organs
0.779 0.221 0.000
Chapter XX External causes of morbidity and mortality
0.779 0.221 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.778 0.222 0.000
H40.0 Glaucoma suspect
0.778 0.222 0.000
F30-F39 Mood [affective] disorders
0.778 0.222 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.776 0.224 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.772 0.227 0.000
S09.9 Unspecified injury of head
0.772 0.228 0.000
I20.0 Unstable angina
0.772 0.228 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.771 0.229 0.000
Chapter XI Diseases of the digestive system
0.771 0.229 0.000
E87.5 Hyperkalaemia
0.770 0.230 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.768 0.232 0.000
H33.3 Retinal breaks without detachment
0.767 0.233 0.000
H40.5 Glaucoma secondary to other eye disorders
0.764 0.236 0.000
Q60-Q64 Congenital malformations of the urinary system
0.761 0.239 0.000
M45-M49 Spondylopathies
0.760 0.240 0.000
T79-T79 Certain early complications of trauma
0.760 0.240 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.758 0.242 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.757 0.243 0.000
S40-S49 Injuries to the shoulder and upper arm
0.756 0.244 0.000
S01 Open wound of head
0.756 0.244 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.755 0.245 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.755 0.245 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.755 0.245 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.755 0.245 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.755 0.245 0.000
Z95.1 Presence of aortocoronary bypass graft
0.753 0.247 0.000
S80-S89 Injuries to the knee and lower leg
0.753 0.247 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.751 0.249 0.000
Z93.2 Ileostomy status
0.750 0.250 0.000
Z95.4 Presence of other heart-valve replacement
0.749 0.251 0.000
I20.8 Other forms of angina pectoris
0.748 0.252 0.000
E88 Other metabolic disorders
0.745 0.255 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.744 0.255 0.000
D03 Melanoma in situ
0.744 0.256 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.744 0.256 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.743 0.257 0.000
E83 Disorders of mineral metabolism
0.742 0.258 0.000
Z89 Acquired absence of limb
0.741 0.259 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.740 0.260 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.739 0.261 0.000
E11.1 With ketoacidosis
0.738 0.262 0.000
M47 Spondylosis
0.738 0.262 0.000
S50-S59 Injuries to the elbow and forearm
0.736 0.264 0.000
E40-E46 Malnutrition
0.736 0.264 0.000
B95-B98 Bacterial, viral and other infectious agents
0.734 0.266 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.733 0.267 0.000
E87.0 Hyperosmolality and hypernatraemia
0.733 0.267 0.000
I44.1 Atrioventricular block, second degree
0.733 0.267 0.000
H10-H13 Disorders of conjunctiva
0.732 0.268 0.000
H35.9 Retinal disorder, unspecified
0.731 0.269 0.000
C18.9 Colon, unspecified
0.730 0.270 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.729 0.271 0.000
Chapter VI Diseases of the nervous system
0.729 0.271 0.000
Z83 Family history of other specific disorders
0.727 0.272 0.000
I74 Arterial embolism and thrombosis
0.726 0.274 0.000
K70-K77 Diseases of liver
0.723 0.277 0.000
S60-S69 Injuries to the wrist and hand
0.723 0.277 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.723 0.277 0.000
D04.7 Skin of lower limb, including hip
0.722 0.278 0.000
I45 Other conduction disorders
0.722 0.278 0.000
E11.3 With ophthalmic complications
0.722 0.278 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.721 0.278 0.000
C64-C68 Malignant neoplasms of urinary tract
0.721 0.279 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.721 0.279 0.000
I33 Acute and subacute endocarditis
0.721 0.279 0.000
I05-I09 Chronic rheumatic heart diseases
0.720 0.280 0.000
H35.8 Other specified retinal disorders
0.720 0.280 0.000
H34 Retinal vascular occlusions
0.719 0.281 0.000
E78.0 Pure hypercholesterolaemia
0.718 0.282 0.000
E10.1 With ketoacidosis
0.718 0.282 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
Z96.7 Presence of other bone and tendon implants
0.716 0.284 0.000
H40.1 Primary open-angle glaucoma
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.715 0.285 0.000
I25.5 Ischaemic cardiomyopathy
0.715 0.285 0.000
I25.4 Coronary artery aneurysm
0.715 0.285 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.715 0.285 0.000
M47.8 Other spondylosis
0.715 0.285 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.715 0.285 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.713 0.287 0.000
E13 Other specified diabetes mellitus
0.712 0.288 0.000
E12 Malnutrition-related diabetes mellitus
0.712 0.288 0.000
L08 Other local infections of skin and subcutaneous tissue
0.712 0.288 0.000
K83 Other diseases of biliary tract
0.712 0.288 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.712 0.288 0.000
Z84 Family history of other conditions
0.711 0.289 0.000
Z81 Family history of mental and behavioural disorders
0.711 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.711 0.289 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.710 0.290 0.000
H31 Other disorders of choroid
0.710 0.290 0.000
H30 Chorioretinal inflammation
0.710 0.290 0.000
Z93.6 Other artificial openings of urinary tract status
0.710 0.290 0.000
I44.3 Other and unspecified atrioventricular block
0.709 0.291 0.000
H54.0 Blindness, both eyes
0.708 0.292 0.000
A30-A49 Other bacterial diseases
0.708 0.292 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.708 0.292 0.000
E20-E35 Disorders of other endocrine glands
0.707 0.293 0.000
S00.8 Superficial injury of other parts of head
0.706 0.294 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.706 0.294 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.705 0.295 0.000
E11.2 With renal complications
0.705 0.295 0.000
T66-T78 Other and unspecified effects of external causes
0.704 0.296 0.000
I24.8 Other forms of acute ischaemic heart disease
0.704 0.296 0.000
E85 Amyloidosis
0.703 0.297 0.000
E84 Cystic fibrosis
0.703 0.297 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.703 0.297 0.000
E79 Disorders of purine and pyrimidine metabolism
0.703 0.297 0.000
E77 Disorders of glycoprotein metabolism
0.703 0.297 0.000
E76 Disorders of glycosaminoglycan metabolism
0.703 0.297 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.703 0.297 0.000
E74 Other disorders of carbohydrate metabolism
0.703 0.297 0.000
E73 Lactose intolerance
0.703 0.297 0.000
E72 Other disorders of amino-acid metabolism
0.703 0.297 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.703 0.297 0.000
E70 Disorders of aromatic amino-acid metabolism
0.703 0.297 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.703 0.297 0.000
H26 Other cataract
0.703 0.297 0.000
F32 Depressive episode
0.702 0.298 0.000
I52 Other heart disorders in diseases classified elsewhere
0.702 0.298 0.000
I48 Atrial fibrillation and flutter
0.702 0.298 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.702 0.298 0.000
I41 Myocarditis in diseases classified elsewhere
0.702 0.298 0.000
I40 Acute myocarditis
0.702 0.298 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.702 0.298 0.000
I37 Pulmonary valve disorders
0.702 0.298 0.000
I36 Nonrheumatic tricuspid valve disorders
0.702 0.298 0.000
I32 Pericarditis in diseases classified elsewhere
0.702 0.298 0.000
S71 Open wound of hip and thigh
0.702 0.298 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.702 0.298 0.000
H27 Other disorders of lens
0.702 0.298 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.700 0.300 0.000
C80 Malignant neoplasm without specification of site
0.700 0.300 0.000
I63.8 Other cerebral infarction
0.699 0.301 0.000
H33.5 Other retinal detachments
0.699 0.301 0.000
S20-S29 Injuries to the thorax
0.699 0.301 0.000
T87 Complications peculiar to reattachment and amputation
0.697 0.303 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.697 0.303 0.000
H33.2 Serous retinal detachment
0.696 0.304 0.000
K65-K67 Diseases of peritoneum
0.693 0.307 0.000
S02 Fracture of skull and facial bones
0.693 0.307 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.692 0.307 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.692 0.307 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.692 0.307 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.692 0.307 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.692 0.307 0.000
L03 Cellulitis
0.692 0.308 0.000
I47.2 Ventricular tachycardia
0.692 0.308 0.000
I31.3 Pericardial effusion (noninflammatory)
0.692 0.308 0.000
I65.2 Occlusion and stenosis of carotid artery
0.691 0.309 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.691 0.309 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.691 0.309 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.691 0.309 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.691 0.309 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.691 0.309 0.000
Z82.2 Family history of deafness and hearing loss
0.691 0.309 0.000
Z82.1 Family history of blindness and visual loss
0.691 0.309 0.000
H25.2 Senile cataract, morgagnian type
0.691 0.309 0.000
Z96.9 Presence of functional implant, unspecified
0.691 0.309 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.691 0.309 0.000
Z96.4 Presence of endocrine implants
0.691 0.309 0.000
Z96.3 Presence of artificial larynx
0.691 0.309 0.000
Z96.2 Presence of otological and audiological implants
0.691 0.309 0.000
I20.1 Angina pectoris with documented spasm
0.690 0.310 0.000
K86 Other diseases of pancreas
0.690 0.310 0.000
H36.0 Diabetic retinopathy
0.690 0.310 0.000
E10.8 With unspecified complications
0.688 0.312 0.000
E10.7 With multiple complications
0.688 0.312 0.000
E10.6 With other specified complications
0.688 0.312 0.000
E10.5 With peripheral circulatory complications
0.688 0.312 0.000
E10.2 With renal complications
0.688 0.312 0.000
E10.0 With coma
0.688 0.312 0.000
D46 Myelodysplastic syndromes
0.688 0.312 0.000
I72 Other aneurysm
0.687 0.312 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.687 0.312 0.000
H44 Disorders of globe
0.687 0.313 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.687 0.313 0.000
S08 Traumatic amputation of part of head
0.687 0.313 0.000
S07 Crushing injury of head
0.687 0.313 0.000
S05 Injury of eye and orbit
0.687 0.313 0.000
S04 Injury of cranial nerves
0.687 0.313 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.687 0.313 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.686 0.314 0.000
F80-F89 Disorders of psychological development
0.686 0.314 0.000
F70-F79 Mental retardation
0.686 0.314 0.000
F60-F69 Disorders of adult personality and behaviour
0.686 0.314 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.686 0.314 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.686 0.314 0.000
H43 Disorders of vitreous body
0.686 0.314 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.685 0.314 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.685 0.315 0.000
I77.6 Arteritis, unspecified
0.685 0.315 0.000
L60-L75 Disorders of skin appendages
0.685 0.315 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.684 0.316 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.682 0.318 0.000
H35.7 Separation of retinal layers
0.681 0.319 0.000
H35.6 Retinal haemorrhage
0.681 0.319 0.000
H35.5 Hereditary retinal dystrophy
0.681 0.319 0.000
H35.4 Peripheral retinal degeneration
0.681 0.319 0.000
H35.2 Other proliferative retinopathy
0.681 0.319 0.000
H35.1 Retinopathy of prematurity
0.681 0.319 0.000
H35.0 Background retinopathy and retinal vascular changes
0.681 0.319 0.000
H52.2 Astigmatism
0.680 0.320 0.000
H52.0 Hypermetropia
0.678 0.322 0.000
I35.0 Aortic (valve) stenosis
0.678 0.322 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.676 0.323 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.676 0.323 0.000
C21 Malignant neoplasm of anus and anal canal
0.676 0.323 0.000
C17 Malignant neoplasm of small intestine
0.676 0.323 0.000
C23 Malignant neoplasm of gallbladder
0.676 0.323 0.000
C18.6 Descending colon
0.675 0.325 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.675 0.325 0.000
E11.8 With unspecified complications
0.674 0.326 0.000
E11.7 With multiple complications
0.674 0.326 0.000
E11.6 With other specified complications
0.674 0.326 0.000
E11.0 With coma
0.674 0.326 0.000
H40.9 Glaucoma, unspecified
0.673 0.327 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.671 0.328 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.671 0.329 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.671 0.329 0.000
I62 Other nontraumatic intracranial haemorrhage
0.671 0.329 0.000
Q61 Cystic kidney disease
0.671 0.329 0.000
H42 Glaucoma in diseases classified elsewhere
0.671 0.329 0.000
Z93.3 Colostomy status
0.671 0.329 0.000
M47.86 Other spondylosis (Lumbar region)
0.670 0.330 0.000
E78.8 Other disorders of lipoprotein metabolism
0.670 0.330 0.000
E78.6 Lipoprotein deficiency
0.670 0.330 0.000
E78.4 Other hyperlipidaemia
0.670 0.330 0.000
E78.3 Hyperchylomicronaemia
0.670 0.330 0.000
E78.2 Mixed hyperlipidaemia
0.670 0.330 0.000
E78.1 Pure hyperglyceridaemia
0.670 0.330 0.000
C18.7 Sigmoid colon
0.670 0.330 0.000
E14.9 Without complications
0.669 0.331 0.000
Q00-Q07 Congenital malformations of the nervous system
0.669 0.331 0.000
E83.1 Disorders of iron metabolism
0.669 0.331 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.669 0.331 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.668 0.332 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.668 0.332 0.000
I70.0 Atherosclerosis of aorta
0.667 0.333 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.666 0.334 0.000
S70 Superficial injury of hip and thigh
0.666 0.334 0.000
I46.9 Cardiac arrest, unspecified
0.666 0.334 0.000
T98 Sequelae of other and unspecified effects of external causes
0.665 0.335 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.664 0.335 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.664 0.336 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.664 0.336 0.000
E87.4 Mixed disorder of acid-base balance
0.664 0.336 0.000
E87.3 Alkalosis
0.664 0.336 0.000
K83.1 Obstruction of bile duct
0.663 0.337 0.000
E50-E64 Other nutritional deficiencies
0.661 0.339 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.659 0.341 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.659 0.341 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.659 0.341 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.659 0.341 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.659 0.341 0.000
C56 Malignant neoplasm of ovary
0.659 0.341 0.000
H55 Nystagmus and other irregular eye movements
0.659 0.341 0.000
E14.3 With ophthalmic complications
0.657 0.343 0.000
I22 Subsequent myocardial infarction
0.657 0.343 0.000
H33.4 Traction detachment of retina
0.657 0.343 0.000
H33.1 Retinoschisis and retinal cysts
0.657 0.343 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.657 0.343 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.657 0.343 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.657 0.343 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.657 0.343 0.000
T83.2 Mechanical complication of graft of urinary organ
0.657 0.343 0.000
H51 Other disorders of binocular movement
0.656 0.344 0.000
H49 Paralytic strabismus
0.656 0.344 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.655 0.345 0.000
E87.7 Fluid overload
0.654 0.346 0.000
Z99.2 Dependence on renal dialysis
0.652 0.348 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.648 0.352 0.000
B15-B19 Viral hepatitis
0.647 0.353 0.000
S06.5 Traumatic subdural haemorrhage
0.647 0.353 0.000
C78.7 Secondary malignant neoplasm of liver
0.646 0.354 0.000
L82 Seborrhoeic keratosis
0.646 0.354 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.646 0.354 0.000
Z99.1 Dependence on respirator
0.646 0.354 0.000
D03.5 Melanoma in situ of trunk
0.645 0.354 0.000
H40.2 Primary angle-closure glaucoma
0.644 0.356 0.000
L10-L14 Bullous disorders
0.643 0.357 0.000
I49.3 Ventricular premature depolarisation
0.640 0.360 0.000
I31.8 Other specified diseases of pericardium
0.640 0.360 0.000
I31.2 Haemopericardium, not elsewhere classified
0.640 0.360 0.000
I31.1 Chronic constrictive pericarditis
0.640 0.360 0.000
I31.0 Chronic adhesive pericarditis
0.640 0.360 0.000
L20-L30 Dermatitis and eczema
0.639 0.361 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.639 0.361 0.000
C25 Malignant neoplasm of pancreas
0.639 0.361 0.000
T17 Foreign body in respiratory tract
0.638 0.361 0.000
H40.8 Other glaucoma
0.638 0.362 0.000
H40.6 Glaucoma secondary to drugs
0.638 0.362 0.000
H40.4 Glaucoma secondary to eye inflammation
0.638 0.362 0.000
H40.3 Glaucoma secondary to eye trauma
0.638 0.362 0.000
H53.6 Night blindness
0.638 0.362 0.000
H53.5 Colour vision deficiencies
0.638 0.362 0.000
H53.3 Other disorders of binocular vision
0.638 0.362 0.000
H52.3 Anisometropia and aniseikonia
0.637 0.363 0.000
I30.9 Acute pericarditis, unspecified
0.637 0.363 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.637 0.363 0.000
L50-L54 Urticaria and erythema
0.636 0.364 0.000
I49.5 Sick sinus syndrome
0.636 0.364 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.636 0.364 0.000
Q80-Q89 Other congenital malformations
0.636 0.364 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.636 0.364 0.000
Q50-Q56 Congenital malformations of genital organs
0.636 0.364 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.636 0.364 0.000
Q35-Q37 Cleft lip and cleft palate
0.636 0.364 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.636 0.364 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.636 0.364 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.635 0.365 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.633 0.367 0.000
I77.8 Other specified disorders of arteries and arterioles
0.633 0.367 0.000
I77.5 Necrosis of artery
0.633 0.367 0.000
I77.4 Coeliac artery compression syndrome
0.633 0.367 0.000
I77.3 Arterial fibromuscular dysplasia
0.633 0.367 0.000
I77.2 Rupture of artery
0.633 0.367 0.000
I77.0 Arteriovenous fistula, acquired
0.633 0.367 0.000
D09 Carcinoma in situ of other and unspecified sites
0.633 0.367 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.633 0.367 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.633 0.367 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.633 0.367 0.000
I44.7 Left bundle-branch block, unspecified
0.632 0.368 0.000
K50-K52 Noninfective enteritis and colitis
0.632 0.368 0.000
H53.9 Visual disturbance, unspecified
0.631 0.369 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.631 0.369 0.000
M40-M43 Deforming dorsopathies
0.630 0.370 0.000
F41 Other anxiety disorders
0.629 0.371 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.629 0.371 0.000
Z93.0 Tracheostomy status
0.628 0.372 0.000
Chapter VIII Diseases of the ear and mastoid process
0.628 0.372 0.000
K76 Other diseases of liver
0.628 0.372 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.627 0.373 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.627 0.373 0.000
Z94.7 Corneal transplant status
0.627 0.373 0.000
Z94.6 Bone transplant status
0.627 0.373 0.000
Z94.5 Skin transplant status
0.627 0.373 0.000
Z94.4 Liver transplant status
0.627 0.373 0.000
Z94.3 Heart and lungs transplant status
0.627 0.373 0.000
Z94.2 Lung transplant status
0.627 0.373 0.000
Z94.1 Heart transplant status
0.627 0.373 0.000
Z93.9 Artificial opening status, unspecified
0.626 0.374 0.000
Z93.8 Other artificial opening status
0.626 0.374 0.000
Z93.5 Cystostomy status
0.626 0.374 0.000
M47.82 Other spondylosis (Cervical region)
0.625 0.375 0.000
C73 Malignant neoplasm of thyroid gland
0.625 0.375 0.000
H54.4 Blindness, one eye
0.624 0.375 0.000
I50 Heart failure
0.624 0.376 0.000
I49.4 Other and unspecified premature depolarisation
0.624 0.376 0.000
D47.1 Chronic myeloproliferative disease
0.624 0.376 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.623 0.376 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.623 0.377 0.000
E11.4 With neurological complications
0.623 0.377 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.623 0.377 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.623 0.377 0.000
L03.1 Cellulitis of other parts of limb
0.623 0.377 0.000
D37.5 Rectum
0.622 0.378 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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