TreeWAS – Variant ID: rs61948673

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
I60-I69 Cerebrovascular diseases	0.999	0.001
M70-M79 Other soft tissue disorders	0.999	0.001
Chapter IX Diseases of the circulatory system	0.998	0.002
M79 Other soft tissue disorders, not elsewhere classified	0.998	0.002
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.998	0.002
Chapter VI Diseases of the nervous system	0.992	0.008
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.991	0.009
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.989	0.011
M20-M25 Other joint disorders	0.988	0.012
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.987	0.013
I63 Cerebral infarction	0.987	0.013
I10-I15 Hypertensive diseases	0.986	0.014
Chapter XXI Factors influencing health status and contact with health services	0.984	0.016
Chapter II Neoplasms	0.979	0.021
Chapter XII Diseases of the skin and subcutaneous tissue	0.978	0.022
Z40-Z54 Persons encountering health services for specific procedures and health care	0.974	0.026
I67 Other cerebrovascular diseases	0.974	0.026
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.973	0.027
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.972	0.028
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.972	0.028
L80-L99 Other disorders of the skin and subcutaneous tissue	0.970	0.030
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.969	0.031
M79.8 Other specified soft tissue disorders	0.966	0.034
I12 Hypertensive renal disease	0.963	0.037
C34 Malignant neoplasm of bronchus and lung	0.962	0.038
M79.2 Neuralgia and neuritis, unspecified	0.959	0.041
G62 Other polyneuropathies	0.958	0.042
Chapter XX External causes of morbidity and mortality	0.955	0.045
C15-C26 Malignant neoplasms of digestive organs	0.955	0.045
C34.9 Bronchus or lung, unspecified	0.953	0.047
I65.2 Occlusion and stenosis of carotid artery	0.953	0.047
Z43 Attention to artificial openings	0.953	0.047
G80-G83 Cerebral palsy and other paralytic syndromes	0.952	0.048
Z00-Z13 Persons encountering health services for examination and investigation	0.951	0.049
D80-D89 Certain disorders involving the immune mechanism	0.951	0.049
Z02.8 Other examinations for administrative purposes	0.950	0.050
Z02 Examination and encounter for administrative purposes	0.950	0.050
Z40 Prophylactic surgery	0.949	0.051
Chapter IV Endocrine, nutritional and metabolic diseases	0.949	0.051
C79 Secondary malignant neoplasm of other sites	0.949	0.051
M25 Other joint disorders, not elsewhere classified	0.948	0.052
I12.0 Hypertensive renal disease with renal failure	0.946	0.054
M24 Other specific joint derangements	0.945	0.055
L97 Ulcer of lower limb, not elsewhere classified	0.939	0.061
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.939	0.061
I64 Stroke, not specified as haemorrhage or infarction	0.938	0.062
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.938	0.062
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.935	0.065
E20-E35 Disorders of other endocrine glands	0.932	0.068
M23 Internal derangement of knee	0.931	0.069
G62.9 Polyneuropathy, unspecified	0.927	0.073
M79.86 Other specified soft tissue disorders (Lower leg)	0.924	0.076
I63.9 Cerebral infarction, unspecified	0.923	0.077
M65-M68 Disorders of synovium and tendon	0.918	0.082
Chapter I Certain infectious and parasitic diseases	0.918	0.082
L85 Other epidermal thickening	0.915	0.085
L83 Acanthosis nigricans	0.913	0.087
M24.1 Other articular cartilage disorders	0.909	0.091
S90-S99 Injuries to the ankle and foot	0.908	0.092
Chapter VIII Diseases of the ear and mastoid process	0.907	0.093
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.905	0.095
T84.0 Mechanical complication of internal joint prosthesis	0.903	0.097
T85 Complications of other internal prosthetic devices, implants and grafts	0.902	0.098
M79.0 Rheumatism, unspecified	0.902	0.098
I67.9 Cerebrovascular disease, unspecified	0.899	0.101
B95-B98 Bacterial, viral and other infectious agents	0.899	0.101
M60-M63 Disorders of muscles	0.897	0.103
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.897	0.103
C79.8 Secondary malignant neoplasm of other specified sites	0.893	0.107
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.893	0.107
Z70-Z76 Persons encountering health services in other circumstances	0.893	0.107
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.888	0.112
M70 Soft tissue disorders related to use, overuse and pressure	0.887	0.113
Z48 Other surgical follow-up care	0.886	0.114
Z43.2 Attention to ileostomy	0.886	0.114
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.883	0.117
D86 Sarcoidosis	0.883	0.117
M25.7 Osteophyte	0.880	0.120
M45-M49 Spondylopathies	0.875	0.125
M05-M14 Inflammatory polyarthropathies	0.874	0.126
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.872	0.128
T84.1 Mechanical complication of internal fixation device of bones of limb	0.872	0.128
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.871	0.129
C25 Malignant neoplasm of pancreas	0.870	0.130
S50-S59 Injuries to the elbow and forearm	0.869	0.131
B97 Viral agents as the cause of diseases classified to other chapters	0.865	0.135
Z72 Problems related to lifestyle	0.861	0.139
D69 Purpura and other haemorrhagic conditions	0.860	0.140
G82 Paraplegia and tetraplegia	0.857	0.143
C19 Malignant neoplasm of rectosigmoid junction	0.857	0.143
Z72.0 Tobacco use	0.856	0.144
H65-H75 Diseases of middle ear and mastoid	0.855	0.145
T82.4 Mechanical complication of vascular dialysis catheter	0.855	0.145
M23.3 Other meniscus derangements	0.852	0.148
I67.1 Cerebral aneurysm, nonruptured	0.852	0.148
E28 Ovarian dysfunction	0.850	0.150
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.849	0.151
T00-T07 Injuries involving multiple body regions	0.848	0.152
W50-W64 Exposure to animate mechanical forces	0.847	0.153
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.846	0.154
I10 Essential (primary) hypertension	0.845	0.155
G50-G59 Nerve, nerve root and plexus disorders	0.845	0.155
E27 Other disorders of adrenal gland	0.841	0.159
G81 Hemiplegia	0.840	0.160
M24.16 Other articular cartilage disorders (Lower leg)	0.840	0.160
G62.0 Drug-induced polyneuropathy	0.838	0.162
Chapter XIV Diseases of the genitourinary system	0.838	0.162
D80 Immunodeficiency with predominantly antibody defects	0.838	0.162
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.837	0.163
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.836	0.164
C23 Malignant neoplasm of gallbladder	0.835	0.165
M79.1 Myalgia	0.834	0.166
M25.75 Osteophyte (Pelvic region and thigh)	0.832	0.168
G40-G47 Episodic and paroxysmal disorders	0.830	0.170
Y40 Systemic antibiotics	0.830	0.170
M79.84 Other specified soft tissue disorders (Hand)	0.829	0.171
E26 Hyperaldosteronism	0.829	0.171
M32 Systemic lupus erythematosus	0.828	0.172
Z49 Care involving dialysis	0.827	0.173
L89 Decubitus ulcer	0.825	0.175
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.825	0.175
T82.3 Mechanical complication of other vascular grafts	0.825	0.175
M24.8 Other specific joint derangements, not elsewhere classified	0.824	0.176
M79.28 Neuralgia and neuritis, unspecified (Other)	0.824	0.176
Z42 Follow-up care involving plastic surgery	0.822	0.178
M79.89 Other specified soft tissue disorders (Site unspecified)	0.822	0.178
L85.9 Epidermal thickening, unspecified	0.822	0.178
M86-M90 Other osteopathies	0.821	0.179
N17-N19 Renal failure	0.820	0.180
C80 Malignant neoplasm without specification of site	0.820	0.180
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.819	0.180
M79.7 Fibromyalgia	0.818	0.182
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.818	0.182
T80 Complications following infusion, transfusion and therapeutic injection	0.816	0.184
N19 Unspecified renal failure	0.816	0.184
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.815	0.185
N25-N29 Other disorders of kidney and ureter	0.813	0.187
Y95 Nosocomial condition	0.811	0.189
C79.9 Secondary malignant neoplasm, unspecified site	0.810	0.190
C77.0 Lymph nodes of head, face and neck	0.810	0.190
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.809	0.191
G83 Other paralytic syndromes	0.809	0.191
L85.8 Other specified epidermal thickening	0.805	0.195
M62 Other disorders of muscle	0.804	0.196
Z03 Medical observation and evaluation for suspected diseases and conditions	0.803	0.197
M45 Ankylosing spondylitis	0.802	0.198
L95 Vasculitis limited to skin, not elsewhere classified	0.802	0.198
M79.80 Other specified soft tissue disorders (Multiple sites)	0.802	0.198
T87 Complications peculiar to reattachment and amputation	0.801	0.199
M67 Other disorders of synovium and tendon	0.800	0.200
M79.6 Pain in limb	0.798	0.202
Z03.4 Observation for suspected myocardial infarction	0.797	0.203
D86.9 Sarcoidosis, unspecified	0.797	0.203
E23 Hypofunction and other disorders of pituitary gland	0.796	0.204
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.796	0.204
G45 Transient cerebral ischaemic attacks and related syndromes	0.795	0.205
M25.5 Pain in joint	0.795	0.205
G63 Polyneuropathy in diseases classified elsewhere	0.795	0.205
S70-S79 Injuries to the hip and thigh	0.791	0.209
I67.2 Cerebral atherosclerosis	0.790	0.210
C37 Malignant neoplasm of thymus	0.790	0.210
I67.0 Dissection of cerebral arteries, nonruptured	0.789	0.211
C17 Malignant neoplasm of small intestine	0.785	0.215
H71 Cholesteatoma of middle ear	0.783	0.217
M25.6 Stiffness of joint, not elsewhere classified	0.782	0.218
M25.3 Other instability of joint	0.782	0.218
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.782	0.218
E65-E68 Obesity and other hyperalimentation	0.780	0.220
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.780	0.220
Z04 Examination and observation for other reasons	0.780	0.220
W20-W49 Exposure to inanimate mechanical forces	0.779	0.221
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.779	0.221
S96 Injury of muscle and tendon at ankle and foot level	0.779	0.221
M91-M94 Chondropathies	0.778	0.222
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.778	0.222
L89.9 Decubitus ulcer and pressure area, unspecified	0.778	0.222
S56 Injury of muscle and tendon at forearm level	0.778	0.222
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.778	0.222
C21 Malignant neoplasm of anus and anal canal	0.776	0.224
N99-N99 Other disorders of the genitourinary system	0.776	0.224
E28.2 Polycystic ovarian syndrome	0.776	0.224
E40-E46 Malnutrition	0.775	0.225
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.775	0.225
Chapter XXII Codes for special purposes	0.774	0.226
N28 Other disorders of kidney and ureter, not elsewhere classified	0.774	0.226
L57 Skin changes due to chronic exposure to nonionising radiation	0.774	0.226
I11 Hypertensive heart disease	0.773	0.227
Z43.4 Attention to other artificial openings of digestive tract	0.773	0.227
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.771	0.229
C34.2 Middle lobe, bronchus or lung	0.771	0.229
C79.7 Secondary malignant neoplasm of adrenal gland	0.770	0.230
D68 Other coagulation defects	0.770	0.230
C34.0 Main bronchus	0.770	0.230
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.770	0.230
Z43.8 Attention to other artificial openings	0.769	0.231
D69.5 Secondary thrombocytopenia	0.768	0.232
E70-E90 Metabolic disorders	0.767	0.233
M79.09 Rheumatism, unspecified (Site unspecified)	0.765	0.235
Z43.3 Attention to colostomy	0.764	0.235
C32 Malignant neoplasm of larynx	0.764	0.236
H66 Suppurative and unspecified otitis media	0.763	0.237
M79.00 Rheumatism, unspecified (Multiple sites)	0.762	0.238
M79.5 Residual foreign body in soft tissue	0.761	0.239
M80-M85 Disorders of bone density and structure	0.760	0.240
G81.9 Hemiplegia, unspecified	0.760	0.240
Z48.0 Attention to surgical dressings and sutures	0.760	0.240
G45.9 Transient cerebral ischaemic attack, unspecified	0.760	0.240
I69 Sequelae of cerebrovascular disease	0.759	0.241
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.758	0.242
T20-T25 Burns and corrosions of external body surface, specified by site	0.758	0.242
S10-S19 Injuries to the neck	0.758	0.242
D60-D64 Aplastic and other anaemias	0.757	0.243
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.755	0.245
E26.0 Primary hyperaldosteronism	0.755	0.245
M46 Other inflammatory spondylopathies	0.755	0.245
L92 Granulomatous disorders of skin and subcutaneous tissue	0.754	0.246
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.754	0.246
G51 Facial nerve disorders	0.753	0.247
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.753	0.247
M70.4 Prepatellar bursitis	0.753	0.247
M79.4 Hypertrophy of (infrapatellar) fat pad	0.751	0.249
M30 Polyarteritis nodosa and related conditions	0.749	0.251
T82.0 Mechanical complication of heart valve prosthesis	0.749	0.251
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.749	0.251
C25.9 Pancreas, unspecified	0.748	0.252
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.747	0.253
L50-L54 Urticaria and erythema	0.746	0.254
S40-S49 Injuries to the shoulder and upper arm	0.746	0.254
T84.3 Mechanical complication of other bone devices, implants and grafts	0.745	0.254
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.745	0.255
Z45 Adjustment and management of implanted device	0.745	0.255
G62.8 Other specified polyneuropathies	0.744	0.256
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.744	0.256
M25.77 Osteophyte (Ankle and foot)	0.744	0.256
G00-G09 Inflammatory diseases of the central nervous system	0.743	0.256
M31 Other necrotising vasculopathies	0.743	0.257
G82.1 Spastic paraplegia	0.743	0.257
B35-B49 Mycoses	0.742	0.258
M65 Synovitis and tenosynovitis	0.741	0.259
M76 Enthesopathies of lower limb, excluding foot	0.741	0.259
Z43.1 Attention to gastrostomy	0.741	0.259
N28.9 Disorder of kidney and ureter, unspecified	0.740	0.260
L10-L14 Bullous disorders	0.740	0.260
E27.1 Primary adrenocortical insufficiency	0.740	0.260
D50-D53 Nutritional anaemias	0.740	0.260
H74 Other disorders of middle ear and mastoid	0.739	0.261
M24.17 Other articular cartilage disorders (Ankle and foot)	0.738	0.262
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.738	0.262
D66 Hereditary factor VIII deficiency	0.737	0.263
C16 Malignant neoplasm of stomach	0.736	0.264
L56 Other acute skin changes due to ultraviolet radiation	0.735	0.265
Z48.9 Surgical follow-up care, unspecified	0.734	0.266
M33 Dermatopolymyositis	0.734	0.266
T85.2 Mechanical complication of intraocular lens	0.733	0.266
V40-V49 Car occupant injured in transport accident	0.733	0.267
Z01.5 Diagnostic skin and sensitisation tests	0.733	0.267
L93 Lupus erythematosus	0.732	0.268
G54 Nerve root and plexus disorders	0.732	0.268
Y57 Other and unspecified drugs and medicaments	0.732	0.268
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.732	0.268
M79.60 Pain in limb (Multiple sites)	0.732	0.268
M25.74 Osteophyte (Hand)	0.731	0.269
A30-A49 Other bacterial diseases	0.731	0.269
Y00-Y09 Assault	0.731	0.269
M70.3 Other bursitis of elbow	0.730	0.270
C25.0 Head of pancreas	0.730	0.270
M66 Spontaneous rupture of synovium and tendon	0.730	0.270
Z04.3 Examination and observation following other accident	0.730	0.270
I70-I79 Diseases of arteries, arterioles and capillaries	0.728	0.272
L40-L45 Papulosquamous disorders	0.727	0.273
T66-T78 Other and unspecified effects of external causes	0.726	0.274
G82.2 Paraplegia, unspecified	0.725	0.275
X50-X57 Overexertion, travel and privation	0.725	0.275
G60 Hereditary and idiopathic neuropathy	0.725	0.275
L94 Other localised connective tissue disorders	0.724	0.276
M25.55 Pain in joint (Pelvic region and thigh)	0.723	0.277
E27.4 Other and unspecified adrenocortical insufficiency	0.722	0.278
I15 Secondary hypertension	0.721	0.279
Y53 Agents primarily affecting the gastro-intestinal system	0.721	0.279
M24.11 Other articular cartilage disorders (Shoulder region)	0.721	0.279
M23.6 Other spontaneous disruption of ligament(s) of knee	0.720	0.280
Y40.8 Other systemic antibiotics	0.718	0.282
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.718	0.282
C80.0 Malignant neoplasm, primary site unknown, so stated	0.718	0.282
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
M34 Systemic sclerosis	0.716	0.284
I68 Cerebrovascular disorders in diseases classified elsewhere	0.716	0.284
Y44 Agents primarily affecting blood constituents	0.716	0.284
M73 Soft tissue disorders in diseases classified elsewhere	0.716	0.284
I00-I02 Acute rheumatic fever	0.716	0.284
M79.9 Soft tissue disorder, unspecified	0.716	0.284
M79.3 Panniculitis, unspecified	0.716	0.284
M05 Seropositive rheumatoid arthritis	0.716	0.284
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.716	0.284
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.715	0.284
E78.0 Pure hypercholesterolaemia	0.715	0.285
M15-M19 Arthrosis	0.715	0.285
M32.1 Systemic lupus erythematosus with organ or system involvement	0.714	0.286
D86.0 Sarcoidosis of lung	0.714	0.286
D55-D59 Haemolytic anaemias	0.713	0.287
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.712	0.288
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.711	0.289
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.711	0.289
M23.8 Other internal derangements of knee	0.711	0.289
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.710	0.290
M25.9 Joint disorder, unspecified	0.709	0.290
M10 Gout	0.709	0.291
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.709	0.291
Z01.6 Radiological examination, not elsewhere classified	0.709	0.291
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.708	0.292
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.708	0.292
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.707	0.292
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.707	0.292
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.707	0.292
I13 Hypertensive heart and renal disease	0.707	0.293
M62.8 Other specified disorders of muscle	0.707	0.293
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.707	0.293
G70-G73 Diseases of myoneural junction and muscle	0.706	0.294
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.706	0.294
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.706	0.294
Y40.0 Penicillins	0.704	0.296
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.704	0.296
M23.2 Derangement of meniscus due to old tear or injury	0.703	0.297
E29 Testicular dysfunction	0.703	0.297
H60-H62 Diseases of external ear	0.702	0.298
C40-C41 Malignant neoplasms of bone and articular cartilage	0.702	0.298
X20-X29 Contact with venomous animals and plants	0.702	0.298
M79.62 Pain in limb (Upper arm)	0.700	0.299
Z43.5 Attention to cyctostomy	0.700	0.300
G44 Other headache syndromes	0.699	0.301
I67.7 Cerebral arteritis, not elsewhere classified	0.698	0.302
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.698	0.302
I67.5 Moyamoya disease	0.698	0.302
I67.4 Hypertensive encephalopathy	0.698	0.302
I67.3 Progressive vascular leukoencephalopathy	0.698	0.302
G64 Other disorders of peripheral nervous system	0.698	0.302
V80-V89 Other land transport accidents	0.698	0.302
S51 Open wound of forearm	0.698	0.302
G83.9 Paralytic syndrome, unspecified	0.697	0.303
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.697	0.303
I65.8 Occlusion and stenosis of other precerebral artery	0.697	0.303
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.697	0.303
I65.1 Occlusion and stenosis of basilar artery	0.697	0.303
I65.0 Occlusion and stenosis of vertebral artery	0.697	0.303
D80.1 Nonfamilial hypogammaglobulinaemia	0.697	0.303
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.697	0.303
C38 Malignant neoplasm of heart, mediastinum and pleura	0.697	0.303
C31 Malignant neoplasm of accessory sinuses	0.697	0.303
C30 Malignant neoplasm of nasal cavity and middle ear	0.697	0.303
C33 Malignant neoplasm of trachea	0.697	0.303
Z43.0 Attention to tracheostomy	0.697	0.303
I12.9 Hypertensive renal disease without renal failure	0.696	0.303
M60 Myositis	0.696	0.304
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.695	0.305
L87 Transepidermal elimination disorders	0.695	0.305
L88 Pyoderma gangrenosum	0.695	0.305
L86 Keratoderma in diseases classified elsewhere	0.695	0.305
A65-A69 Other spirochaetal diseases	0.695	0.305
C76 Malignant neoplasm of other and ill-defined sites	0.695	0.305
T82.1 Mechanical complication of cardiac electronic device	0.694	0.306
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.694	0.306
M00-M03 Infectious arthropathies	0.693	0.307
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.693	0.307
M67.4 Ganglion	0.693	0.307
M79.81 Other specified soft tissue disorders (Shoulder region)	0.693	0.307
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.693	0.307
C48.2 Peritoneum, unspecified	0.692	0.308
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.691	0.309
C79.2 Secondary malignant neoplasm of skin	0.691	0.309
S90 Superficial injury of ankle and foot	0.690	0.310
Z75 Problems related to medical facilities and other health care	0.690	0.310
C34.8 Overlapping lesion of bronchus and lung	0.690	0.310
M70.7 Other bursitis of hip	0.689	0.311
M23.1 Discoid meniscus (congenital)	0.688	0.312
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.688	0.312
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.688	0.312
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.688	0.312
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.688	0.312
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.688	0.312
G62.2 Polyneuropathy due to other toxic agents	0.687	0.313
G62.1 Alcoholic polyneuropathy	0.687	0.313
N28.1 Cyst of kidney, acquired	0.687	0.313
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.686	0.314
M23.4 Loose body in knee	0.686	0.314
M40-M43 Deforming dorsopathies	0.685	0.315
S79 Other and unspecified injuries of hip and thigh	0.685	0.315
E23.0 Hypopituitarism	0.685	0.315
Y35-Y36 Legal intervention and operations of war	0.685	0.315
Y10-Y34 Event of undetermined intent	0.685	0.315
X85-X99 Assault	0.685	0.315
X30-X39 Exposure to forces of nature	0.685	0.315
X10-X19 Contact with heat and hot substances	0.685	0.315
X00-X09 Exposure to smoke, fire and flames	0.685	0.315
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.685	0.315
W75-W84 Other accidental threats to breathing	0.685	0.315
W65-W74 Accidental drowning and submersion	0.685	0.315
V98-V99 Other and unspecified transport accidents	0.685	0.315
V95-V97 Air and space transport accidents	0.685	0.315
V90-V94 Water transport accidents	0.685	0.315
V70-V79 Bus occupant injured in transport accident	0.685	0.315
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.685	0.315
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.685	0.315
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.685	0.315
V01-V09 Pedestrian injured in transport accident	0.685	0.315
Z42.8 Follow-up care involving plastic surgery of other body part	0.684	0.315
I71 Aortic aneurysm and dissection	0.684	0.316
Y40.1 Cefalosporins and other -lactam antibiotics	0.684	0.316
X40-X49 Accidental poisoning by and exposure to noxious substances	0.684	0.316
Z43.9 Attention to unspecified artificial opening	0.683	0.317
Z43.7 Attention to artificial vagina	0.683	0.317
M79.19 Myalgia (Site unspecified)	0.683	0.317
H69 Other disorders of Eustachian tube	0.683	0.317
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.683	0.317
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.682	0.318
L95.9 Vasculitis limited to skin, unspecified	0.682	0.318
Z10 Routine general health check-up of defined subpopulation	0.682	0.318
Z50 Care involving use of rehabilitation procedures	0.682	0.318
D84 Other immunodeficiencies	0.681	0.318
D83 Common variable immunodeficiency	0.681	0.318
D82 Immunodeficiency associated with other major defects	0.681	0.318
D81 Combined immunodeficiencies	0.681	0.318
Z02.9 Examination for administrative purposes, unspecified	0.681	0.319
Z02.7 Issue of medical certificate	0.681	0.319
Z02.6 Examination for insurance purposes	0.681	0.319
Z02.5 Examination for participation in sport	0.681	0.319
Z02.4 Examination for driving licence	0.681	0.319
Z02.3 Examination for recruitment to armed forces	0.681	0.319
Z02.2 Examination for admission to residential institution	0.681	0.319
Z02.1 Pre-employment examination	0.681	0.319
Z02.0 Examination for admission to educational institution	0.681	0.319
M23.0 Cystic meniscus	0.681	0.319
T00 Superficial injuries involving multiple body regions	0.681	0.319
Z40.9 Prophylactic surgery, unspecified	0.680	0.319
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.680	0.319
W55 Bitten or struck by other mammals	0.680	0.320
M25.54 Pain in joint (Hand)	0.680	0.320
Z44 Fitting and adjustment of external prosthetic device	0.680	0.320
S99 Other and unspecified injuries of ankle and foot	0.680	0.320
M25.2 Flail joint	0.680	0.320
M25.1 Fistula of joint	0.680	0.320
Z03.1 Observation for suspected malignant neoplasm	0.679	0.321
W22 Striking against or struck by other objects	0.679	0.321
Z43.6 Attention to other artificial openings of urinary tract	0.679	0.321
G51.0 Bell's palsy	0.678	0.322
Q50-Q56 Congenital malformations of genital organs	0.678	0.322
Z48.8 Other specified surgical follow-up care	0.678	0.322
A15-A19 Tuberculosis	0.678	0.322
M25.8 Other specified joint disorders	0.678	0.322
M24.9 Joint derangement, unspecified	0.677	0.323
M24.7 Protrusio acetabuli	0.677	0.323
M24.6 Ankylosis of joint	0.677	0.323
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.677	0.323
M13 Other arthritis	0.677	0.323
C49 Malignant neoplasm of other connective and soft tissue	0.677	0.323
D86.8 Sarcoidosis of other and combined sites	0.676	0.323
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.676	0.324
M18 Arthrosis of first carpometacarpal joint	0.676	0.324
D68.8 Other specified coagulation defects	0.675	0.325
D69.3 Idiopathic thrombocytopenic purpura	0.674	0.326
X58-X59 Accidental exposure to other and unspecified factors	0.673	0.326
W60 Contact with plant thorns and spines and sharp leaves	0.673	0.327
D67 Hereditary factor IX deficiency	0.673	0.327
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.673	0.327
M77 Other enthesopathies	0.672	0.328
M22 Disorders of patella	0.671	0.328
M79.08 Rheumatism, unspecified (Other)	0.670	0.330
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.670	0.330
B50-B64 Protozoal diseases	0.669	0.331
C26 Malignant neoplasm of other and ill-defined digestive organs	0.669	0.331
M23.9 Internal derangement of knee, unspecified	0.669	0.331
M46.9 Inflammatory spondylopathy, unspecified	0.669	0.331
Y49 Psychotropic drugs, not elsewhere classified	0.668	0.331
E35 Disorders of endocrine glands in diseases classified elsewhere	0.668	0.332
E32 Diseases of thymus	0.668	0.332
E31 Polyglandular dysfunction	0.668	0.332
E30 Disorders of puberty, not elsewhere classified	0.668	0.332
E25 Adrenogenital disorders	0.668	0.332
G63.2 Diabetic polyneuropathy	0.667	0.333
B90-B94 Sequelae of infectious and parasitic diseases	0.666	0.334
T87.6 Other and unspecified complications of amputation stump	0.666	0.334
Y43 Primarily systemic agents	0.666	0.334
X60-X84 Intentional self-harm	0.665	0.335
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.665	0.335
G52 Disorders of other cranial nerves	0.665	0.335
M24.2 Disorder of ligament	0.664	0.335
N26 Unspecified contracted kidney	0.664	0.335
D62 Acute posthaemorrhagic anaemia	0.664	0.336
C34.1 Upper lobe, bronchus or lung	0.664	0.336
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.664	0.336
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.663	0.337
N27 Small kidney of unknown cause	0.662	0.338
B37 Candidiasis	0.662	0.338
M18.1 Other primary arthrosis of first carpometacarpal joint	0.662	0.338

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations