TreeWAS – Variant ID: rs62009784

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
M05-M14 Inflammatory polyarthropathies	0.999	0.001
Chapter V Mental and behavioural disorders	0.992	0.008
M13 Other arthritis	0.988	0.012
M45-M49 Spondylopathies	0.987	0.013
S60-S69 Injuries to the wrist and hand	0.986	0.014
M13.9 Arthritis, unspecified	0.980	0.020
M50-M54 Other dorsopathies	0.978	0.022
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.975	0.025
M48 Other spondylopathies	0.969	0.031
M13.99 Arthritis, unspecified (Site unspecified)	0.965	0.035
S61 Open wound of wrist and hand	0.964	0.036
M06 Other rheumatoid arthritis	0.962	0.038
F40-F48 Neurotic, stress-related and somatoform disorders	0.962	0.038
S20-S29 Injuries to the thorax	0.961	0.039
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.950	0.050
M65-M68 Disorders of synovium and tendon	0.949	0.051
Chapter X Diseases of the respiratory system	0.944	0.056
M48.0 Spinal stenosis	0.943	0.057
Chapter I Certain infectious and parasitic diseases	0.932	0.068
F41 Other anxiety disorders	0.927	0.073
M20-M25 Other joint disorders	0.920	0.080
Chapter XX External causes of morbidity and mortality	0.918	0.082
T66-T78 Other and unspecified effects of external causes	0.914	0.086
M65 Synovitis and tenosynovitis	0.913	0.087
Chapter VIII Diseases of the ear and mastoid process	0.910	0.090
M06.9 Rheumatoid arthritis, unspecified	0.909	0.091
S10-S19 Injuries to the neck	0.906	0.094
J95-J99 Other diseases of the respiratory system	0.901	0.099
T92 Sequelae of injuries of upper limb	0.893	0.107
M50 Cervical disk disorders	0.888	0.112
M48.07 Spinal stenosis (Lumbosacral region)	0.887	0.113
S61.0 Open wound of finger(s) without damage to nail	0.886	0.114
F41.9 Anxiety disorder, unspecified	0.885	0.115
M65.9 Synovitis and tenosynovitis, unspecified	0.884	0.116
M25 Other joint disorders, not elsewhere classified	0.883	0.117
S22 Fracture of rib(s), sternum and thoracic spine	0.882	0.118
F30-F39 Mood [affective] disorders	0.882	0.118
S61.8 Open wound of other parts of wrist and hand	0.876	0.124
H90-H95 Other disorders of ear	0.875	0.125
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.872	0.128
D80-D89 Certain disorders involving the immune mechanism	0.870	0.130
M13.98 Arthritis, unspecified (Other)	0.869	0.131
M54 Dorsalgia	0.868	0.132
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.868	0.132
M11 Other crystal arthropathies	0.866	0.134
D60-D64 Aplastic and other anaemias	0.862	0.138
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.862	0.138
M46 Other inflammatory spondylopathies	0.858	0.142
M51 Other intervertebral disk disorders	0.858	0.142
M13.94 Arthritis, unspecified (Hand)	0.857	0.143
J90-J94 Other diseases of pleura	0.855	0.145
Chapter XII Diseases of the skin and subcutaneous tissue	0.854	0.146
T78 Adverse effects, not elsewhere classified	0.853	0.147
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.850	0.150
M13.93 Arthritis, unspecified (Forearm)	0.847	0.153
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.846	0.154
S40-S49 Injuries to the shoulder and upper arm	0.839	0.161
H93 Other disorders of ear, not elsewhere classified	0.839	0.161
J80-J84 Other respiratory diseases principally affecting the interstitium	0.838	0.162
D63 Anaemia in chronic diseases classified elsewhere	0.838	0.162
B95-B98 Bacterial, viral and other infectious agents	0.835	0.165
J99 Respiratory disorders in diseases classified elsewhere	0.835	0.165
M48.5 Collapsed vertebra, not elsewhere classified	0.829	0.171
M54.9 Dorsalgia, unspecified	0.828	0.172
T98 Sequelae of other and unspecified effects of external causes	0.827	0.173
S90-S99 Injuries to the ankle and foot	0.826	0.174
M34 Systemic sclerosis	0.823	0.177
F31 Bipolar affective disorder	0.823	0.177
F80-F89 Disorders of psychological development	0.820	0.180
S20 Superficial injury of thorax	0.819	0.180
S12 Fracture of neck	0.816	0.184
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.815	0.185
D69 Purpura and other haemorrhagic conditions	0.814	0.186
B65-B83 Helminthiases	0.814	0.186
J92 Pleural plaque	0.814	0.186
M40-M43 Deforming dorsopathies	0.813	0.187
H93.1 Tinnitus	0.813	0.187
M07 Psoriatic and enteropathic arthropathies	0.811	0.189
M50.0 Cervical disk disorder with myelopathy	0.810	0.190
M48.02 Spinal stenosis (Cervical region)	0.807	0.193
S27 Injury of other and unspecified intrathoracic organs	0.806	0.194
S69 Other and unspecified injuries of wrist and hand	0.804	0.196
F99-F99 Unspecified mental disorder	0.797	0.203
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.797	0.203
J84 Other interstitial pulmonary diseases	0.796	0.204
D63.0 Anaemia in neoplastic disease	0.794	0.206
S22.3 Fracture of rib	0.794	0.206
Y60-Y69 Misadventures to patients during surgical and medical care	0.793	0.207
L60-L75 Disorders of skin appendages	0.793	0.207
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.788	0.212
Y52 Agents primarily affecting the cardiovascular system	0.787	0.213
S70-S79 Injuries to the hip and thigh	0.787	0.213
M54.99 Dorsalgia, unspecified (Site unspecified)	0.786	0.214
F00-F09 Organic, including symptomatic, mental disorders	0.786	0.214
M48.09 Spinal stenosis (Site unspecified)	0.785	0.215
M31 Other necrotising vasculopathies	0.784	0.216
T91 Sequelae of injuries of neck and trunk	0.781	0.219
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.778	0.222
M13.97 Arthritis, unspecified (Ankle and foot)	0.775	0.225
M54.3 Sciatica	0.775	0.225
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.775	0.225
S66 Injury of muscle and tendon at wrist and hand level	0.774	0.226
S61.9 Open wound of wrist and hand, part unspecified	0.772	0.228
S62 Fracture at wrist and hand level	0.772	0.228
M11.2 Other chondrocalcinosis	0.771	0.229
M06.0 Seronegative rheumatoid arthritis	0.771	0.229
J84.1 Other interstitial pulmonary diseases with fibrosis	0.770	0.230
T93 Sequelae of injuries of lower limb	0.769	0.231
S65 Injury of blood vessels at wrist and hand level	0.769	0.231
M25.4 Effusion of joint	0.768	0.232
F43 Reaction to severe stress, and adjustment disorders	0.768	0.232
L60 Nail disorders	0.767	0.233
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.766	0.234
M46.9 Inflammatory spondylopathy, unspecified	0.766	0.234
M60-M63 Disorders of muscles	0.766	0.234
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.766	0.234
F20 Schizophrenia	0.763	0.237
H91 Other hearing loss	0.760	0.240
M45 Ankylosing spondylitis	0.758	0.242
Y57 Other and unspecified drugs and medicaments	0.756	0.244
T90 Sequelae of injuries of head	0.756	0.244
D84 Other immunodeficiencies	0.754	0.245
M00-M03 Infectious arthropathies	0.753	0.247
J98 Other respiratory disorders	0.753	0.247
F45 Somatoform disorders	0.751	0.249
J99.8 Respiratory disorders in other diseases classified elsewhere	0.751	0.249
M91-M94 Chondropathies	0.748	0.252
M06.4 Inflammatory polyarthropathy	0.748	0.252
F41.1 Generalised anxiety disorder	0.747	0.253
D55-D59 Haemolytic anaemias	0.746	0.253
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.746	0.254
T78.4 Allergy, unspecified	0.745	0.255
M25.6 Stiffness of joint, not elsewhere classified	0.745	0.255
V40-V49 Car occupant injured in transport accident	0.744	0.256
M14 Arthropathies in other diseases classified elsewhere	0.744	0.256
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.743	0.257
J92.0 Pleural plaque with presence of asbestos	0.742	0.258
D63.8 Anaemia in other chronic diseases classified elsewhere	0.740	0.260
S50-S59 Injuries to the elbow and forearm	0.739	0.261
B90-B94 Sequelae of infectious and parasitic diseases	0.739	0.261
L60.8 Other nail disorders	0.738	0.262
S68 Traumatic amputation of wrist and hand	0.738	0.262
S60 Superficial injury of wrist and hand	0.737	0.262
M86-M90 Other osteopathies	0.737	0.263
M13.0 Polyarthritis, unspecified	0.736	0.264
M50.3 Other cervical disk degeneration	0.736	0.264
M51.8 Other specified intervertebral disk disorders	0.735	0.265
S00-S09 Injuries to the head	0.733	0.267
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.732	0.268
S22.30 Fracture of rib (closed)	0.731	0.269
S61.1 Open wound of finger(s) with damage to nail	0.730	0.270
S22.4 Multiple fractures of ribs	0.730	0.270
B80 Enterobiasis	0.730	0.270
T92.1 Sequelae of fracture of arm	0.729	0.271
J93 Pneumothorax	0.729	0.271
B25-B34 Other viral diseases	0.729	0.271
T15-T19 Effects of foreign body entering through natural orifice	0.728	0.272
T78.3 Angioneurotic oedema	0.725	0.275
M25.0 Haemarthrosis	0.724	0.276
D69.3 Idiopathic thrombocytopenic purpura	0.724	0.276
S30 Superficial injury of abdomen, lower back and pelvis	0.723	0.277
M25.9 Joint disorder, unspecified	0.722	0.278
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.720	0.280
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.720	0.280
S46 Injury of muscle and tendon at shoulder and upper arm level	0.720	0.280
J92.9 Pleural plaque without asbestos	0.719	0.281
T92.9 Sequelae of unspecified injury of upper limb	0.719	0.281
M06.3 Rheumatoid nodule	0.717	0.282
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
W50-W64 Exposure to animate mechanical forces	0.717	0.283
M12 Other specific arthropathies	0.716	0.284
M09 Juvenile arthritis in diseases classified elsewhere	0.716	0.284
M08 Juvenile arthritis	0.716	0.284
F20.9 Schizophrenia, unspecified	0.716	0.284
V20-V29 Motorcycle rider injured in transport accident	0.716	0.284
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.712	0.288
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.712	0.288
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.711	0.289
F70-F79 Mental retardation	0.711	0.289
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.711	0.289
M25.46 Effusion of joint (Lower leg)	0.710	0.290
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.709	0.291
Y53 Agents primarily affecting the gastro-intestinal system	0.709	0.291
M13.8 Other specified arthritis	0.708	0.291
M13.1 Monoarthritis, not elsewhere classified	0.708	0.291
M49 Spondylopathies in diseases classified elsewhere	0.707	0.292
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.706	0.294
T94 Sequelae of injuries involving multiple and unspecified body regions	0.705	0.294
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.705	0.295
M65.4 Radial styloid tenosynovitis [de Quervain]	0.704	0.296
M11.26 Other chondrocalcinosis (Lower leg)	0.703	0.297
M13.92 Arthritis, unspecified (Upper arm)	0.702	0.298
M66 Spontaneous rupture of synovium and tendon	0.701	0.299
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.701	0.299
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.700	0.300
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.699	0.301
T95 Sequelae of burns, corrosions and frostbite	0.699	0.301
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.699	0.301
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.699	0.301
S92 Fracture of foot, except ankle	0.699	0.301
W20-W49 Exposure to inanimate mechanical forces	0.698	0.302
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.697	0.303
S10 Superficial injury of neck	0.697	0.303
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.696	0.304
D69.6 Thrombocytopenia, unspecified	0.696	0.304
F81 Specific developmental disorders of scholastic skills	0.696	0.304
S61.7 Multiple open wounds of wrist and hand	0.696	0.304
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.696	0.304
J95 Postprocedural respiratory disorders, not elsewhere classified	0.695	0.305
M48.9 Spondylopathy, unspecified	0.695	0.305
M48.8 Other specified spondylopathies	0.695	0.305
M48.4 Fatigue fracture of vertebra	0.695	0.305
M48.3 Traumatic spondylopathy	0.695	0.305
M48.2 Kissing spine	0.695	0.305
M48.1 Ankylosing hyperostosis [Forestier]	0.695	0.305
T79-T79 Certain early complications of trauma	0.694	0.305
M51.9 Intervertebral disk disorder, unspecified	0.693	0.307
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.692	0.308
M06.8 Other specified rheumatoid arthritis	0.690	0.310
M06.2 Rheumatoid bursitis	0.690	0.310
M06.1 Adult-onset Still's disease	0.690	0.310
F48 Other neurotic disorders	0.690	0.310
F44 Dissociative [conversion] disorders	0.690	0.310
M53 Other dorsopathies, not elsewhere classified	0.690	0.310
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.689	0.311
S26 Injury of heart	0.689	0.311
S25 Injury of blood vessels of thorax	0.689	0.311
S24 Injury of nerves and spinal cord at thorax level	0.689	0.311
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.689	0.311
S21 Open wound of thorax	0.689	0.311
M43 Other deforming dorsopathies	0.688	0.312
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.688	0.312
D80 Immunodeficiency with predominantly antibody defects	0.687	0.312
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.687	0.313
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.687	0.313
M54.39 Sciatica (Site unspecified)	0.686	0.314
F31.6 Bipolar affective disorder, current episode mixed	0.686	0.314
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.685	0.315
S32 Fracture of lumbar spine and pelvis	0.684	0.316
M34.9 Systemic sclerosis, unspecified	0.684	0.316
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.684	0.316
M34.8 Other forms of systemic sclerosis	0.680	0.319
S22.1 Multiple fractures of thoracic spine	0.680	0.320
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.680	0.320
Chapter XV Pregnancy, childbirth and the puerperium	0.680	0.320
F30 Manic episode	0.680	0.320
M65.1 Other infective (teno)synovitis	0.679	0.321
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.679	0.321
F42 Obsessive-compulsive disorder	0.679	0.321
T92.2 Sequelae of fracture at wrist and hand level	0.678	0.322
M07.3 Other psoriatic arthropathies	0.677	0.323
S79 Other and unspecified injuries of hip and thigh	0.677	0.323
M48.05 Spinal stenosis (Thoracolumbar region)	0.676	0.324
M48.04 Spinal stenosis (Thoracic region)	0.676	0.324
M48.03 Spinal stenosis (Cervicothoracic region)	0.676	0.324
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.676	0.324
B35-B49 Mycoses	0.676	0.324
J60-J70 Lung diseases due to external agents	0.675	0.325
M25.8 Other specified joint disorders	0.675	0.325
M54.4 Lumbago with sciatica	0.675	0.325
J40-J47 Chronic lower respiratory diseases	0.675	0.325
S69.9 Unspecified injury of wrist and hand	0.674	0.325
S50 Superficial injury of forearm	0.674	0.326
M23 Internal derangement of knee	0.674	0.326
D84.9 Immunodeficiency, unspecified	0.672	0.328
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.671	0.329
M10 Gout	0.670	0.330
T92.8 Sequelae of other specified injuries of upper limb	0.670	0.330
M25.7 Osteophyte	0.670	0.330
S19 Other and unspecified injuries of neck	0.669	0.330
S91 Open wound of ankle and foot	0.669	0.331
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.669	0.331
S12.1 Fracture of second cervical vertebra	0.668	0.332
F40 Phobic anxiety disorders	0.668	0.332
B99-B99 Other infectious diseases	0.668	0.332
B85-B89 Pediculosis, acariasis and other infestations	0.668	0.332
B50-B64 Protozoal diseases	0.668	0.332
B20-B24 Human immunodeficiency virus [HIV] disease	0.668	0.332
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.668	0.332
A75-A79 Rickettsioses	0.668	0.332
A70-A74 Other diseases caused by chlamydiae	0.668	0.332
A65-A69 Other spirochaetal diseases	0.668	0.332
A20-A28 Certain zoonotic bacterial diseases	0.668	0.332
A15-A19 Tuberculosis	0.668	0.332
A80-A89 Viral infections of the central nervous system	0.667	0.333
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.666	0.334
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.666	0.334
M48.00 Spinal stenosis (Multiple sites in spine)	0.666	0.334
L20-L30 Dermatitis and eczema	0.666	0.334
M13.96 Arthritis, unspecified (Lower leg)	0.665	0.335
S27.0 Traumatic pneumothorax	0.665	0.335
F41.8 Other specified anxiety disorders	0.665	0.335
F41.3 Other mixed anxiety disorders	0.665	0.335
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.664	0.336
S12.2 Fracture of other specified cervical vertebra	0.664	0.336
S12.7 Multiple fractures of cervical spine	0.663	0.337
L71 Rosacea	0.662	0.338
H91.9 Hearing loss, unspecified	0.660	0.340
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.660	0.340
M33 Dermatopolymyositis	0.660	0.340
M32 Systemic lupus erythematosus	0.660	0.340
M30 Polyarteritis nodosa and related conditions	0.660	0.340
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.660	0.340
S62.6 Fracture of other finger	0.659	0.341
Y35-Y36 Legal intervention and operations of war	0.658	0.342
Y10-Y34 Event of undetermined intent	0.658	0.342
Y00-Y09 Assault	0.658	0.342
X85-X99 Assault	0.658	0.342
X30-X39 Exposure to forces of nature	0.658	0.342
X20-X29 Contact with venomous animals and plants	0.658	0.342
X10-X19 Contact with heat and hot substances	0.658	0.342
X00-X09 Exposure to smoke, fire and flames	0.658	0.342
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.658	0.342
W75-W84 Other accidental threats to breathing	0.658	0.342
W65-W74 Accidental drowning and submersion	0.658	0.342
V98-V99 Other and unspecified transport accidents	0.658	0.342
V95-V97 Air and space transport accidents	0.658	0.342
V90-V94 Water transport accidents	0.658	0.342
V70-V79 Bus occupant injured in transport accident	0.658	0.342
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.658	0.342
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.658	0.342
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.658	0.342
V01-V09 Pedestrian injured in transport accident	0.658	0.342
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.658	0.342
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.657	0.343
F99 Mental disorder, not otherwise specified	0.657	0.343
S20.8 Superficial injuries of other and unspecified parts of thorax	0.657	0.343
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.656	0.344
X58-X59 Accidental exposure to other and unspecified factors	0.656	0.344
T75 Effects of other external causes	0.655	0.344
T74 Maltreatment syndromes	0.655	0.344
T73 Effects of other deprivation	0.655	0.344
T70 Effects of air pressure and water pressure	0.655	0.344
T69 Other effects of reduced temperature	0.655	0.344
T67 Effects of heat and light	0.655	0.344
T71 Asphyxiation	0.655	0.344
T68 Hypothermia	0.655	0.344
T66 Unspecified effects of radiation	0.655	0.344
S00 Superficial injury of head	0.656	0.344
M67 Other disorders of synovium and tendon	0.654	0.346
M65.2 Calcific tendinitis	0.654	0.346
M65.0 Abscess of tendon sheath	0.654	0.346
M65.8 Other synovitis and tenosynovitis	0.654	0.346
F60-F69 Disorders of adult personality and behaviour	0.652	0.347
M06.98 Rheumatoid arthritis, unspecified (Other)	0.652	0.348
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.652	0.348
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.652	0.348
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.651	0.349
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.651	0.349
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.650	0.350
J98.0 Diseases of bronchus, not elsewhere classified	0.650	0.350
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.650	0.350
X40-X49 Accidental poisoning by and exposure to noxious substances	0.649	0.350
S17 Crushing injury of neck	0.649	0.351
S15 Injury of blood vessels at neck level	0.649	0.351
S14 Injury of nerves and spinal cord at neck level	0.649	0.351
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.649	0.351
S11 Open wound of neck	0.649	0.351
S18 Traumatic amputation at neck level	0.649	0.351
S16 Injury of muscle and tendon at neck level	0.649	0.351
F32 Depressive episode	0.649	0.351
Y51 Drugs primarily affecting the autonomic nervous system	0.649	0.351
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.648	0.352
J09-J18 Influenza and pneumonia	0.648	0.352
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.647	0.353
D69.5 Secondary thrombocytopenia	0.647	0.353
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.646	0.354
J96 Respiratory failure, not elsewhere classified	0.646	0.354
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.644	0.355
S64 Injury of nerves at wrist and hand level	0.644	0.356
B15-B19 Viral hepatitis	0.644	0.356
M50.1 Cervical disk disorder with radiculopathy	0.643	0.357
V80-V89 Other land transport accidents	0.643	0.357
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.643	0.357
T78.0 Anaphylactic shock due to adverse food reaction	0.642	0.358
M31.6 Other giant cell arteritis	0.642	0.358
S29 Other and unspecified injuries of thorax	0.642	0.358
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.641	0.359
T92.4 Sequelae of injury of nerve of upper limb	0.641	0.359
T78.2 Anaphylactic shock, unspecified	0.640	0.360
S20.2 Contusion of thorax	0.639	0.360
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.639	0.361
J86 Pyothorax	0.639	0.361
M50.9 Cervical disk disorder, unspecified	0.637	0.363
M50.8 Other cervical disk disorders	0.637	0.363
Y52.3 Coronary vasodilators, not elsewhere classified	0.637	0.363
X50-X57 Overexertion, travel and privation	0.635	0.365
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.634	0.366
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.634	0.366
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.634	0.366
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.634	0.366
M25.2 Flail joint	0.633	0.367
M25.1 Fistula of joint	0.633	0.367
S20.3 Other superficial injuries of front wall of thorax	0.633	0.367
S22.9 Fracture of bony thorax, part unspecified	0.633	0.367
S22.8 Fracture of other parts of bony thorax	0.633	0.367
S22.5 Flail chest	0.633	0.367
M34.1 CR(E)ST syndrome	0.633	0.367
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.633	0.367
F38 Other mood [affective] disorders	0.632	0.368
F34 Persistent mood [affective] disorders	0.632	0.368
F39 Unspecified mood [affective] disorder	0.632	0.368
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.632	0.368
J91 Pleural effusion in conditions classified elsewhere	0.631	0.369
J93.9 Pneumothorax, unspecified	0.631	0.369
S22.0 Fracture of thoracic vertebra	0.629	0.371
H94 Other disorders of ear in diseases classified elsewhere	0.627	0.372
X60-X84 Intentional self-harm	0.627	0.373
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.627	0.373
D89.9 Disorder involving the immune mechanism, unspecified	0.627	0.373
F31.9 Bipolar affective disorder, unspecified	0.627	0.373
Y60.0 During surgical operation	0.626	0.374
Y59 Other and unspecified vaccines and biological substances	0.625	0.375
Y58 Bacterial vaccines	0.625	0.375
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.625	0.375
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.625	0.375
Y50 Central nervous system stimulants, not elsewhere classified	0.625	0.375
Y49 Psychotropic drugs, not elsewhere classified	0.625	0.375
Y48 Anaesthetics and therapeutic gases	0.625	0.375
Y47 Sedatives, hypnotics and antianxiety drugs	0.625	0.375
Y46 Antiepileptics and anti-Parkinsonism drugs	0.625	0.375
Y52.4 Angiotensin-converting-enzyme inhibitors	0.625	0.375
T92.0 Sequelae of open wound of upper limb	0.625	0.375
S27.3 Other injuries of lung	0.624	0.376
L57 Skin changes due to chronic exposure to nonionising radiation	0.624	0.376
M80-M85 Disorders of bone density and structure	0.624	0.376
D83 Common variable immunodeficiency	0.624	0.376
D82 Immunodeficiency associated with other major defects	0.624	0.376
D81 Combined immunodeficiencies	0.624	0.376
M54.8 Other dorsalgia	0.622	0.377
M54.0 Panniculitis affecting regions of neck and back	0.622	0.377
J47 Bronchiectasis	0.622	0.378
H65-H75 Diseases of middle ear and mastoid	0.622	0.378
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.622	0.378
F05 Delirium, not induced by alcohol and other psychoactive substances	0.621	0.379
M11.9 Crystal arthropathy, unspecified	0.621	0.379
M11.8 Other specified crystal arthropathies	0.621	0.379
M11.1 Familial chondrocalcinosis	0.621	0.379
M11.0 Hydroxyapatite deposition disease	0.621	0.379
F25 Schizoaffective disorders	0.621	0.379
S22.40 Multiple fractures of ribs (closed)	0.621	0.379
Y57.9 Drug or medicament, unspecified	0.620	0.380
M54.94 Dorsalgia, unspecified (Thoracic region)	0.620	0.380
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.619	0.380
J98.8 Other specified respiratory disorders	0.619	0.381
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.618	0.382
D67 Hereditary factor IX deficiency	0.618	0.382
D66 Hereditary factor VIII deficiency	0.618	0.382
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.618	0.382
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.617	0.383
S71 Open wound of hip and thigh	0.616	0.384
M24 Other specific joint derangements	0.616	0.384
S80-S89 Injuries to the knee and lower leg	0.616	0.384
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.616	0.384
M46.8 Other specified inflammatory spondylopathies	0.615	0.384
M46.5 Other infective spondylopathies	0.615	0.384
M46.4 Discitis, unspecified	0.615	0.384
M46.3 Infection of intervertebral disk (pyogenic)	0.615	0.384
M46.2 Osteomyelitis of vertebra	0.615	0.384
M46.1 Sacro-iliitis, not elsewhere classified	0.615	0.384
M46.0 Spinal enthesopathy	0.615	0.384
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.615	0.384
D61 Other aplastic anaemias	0.615	0.385
M51.3 Other specified intervertebral disk degeneration	0.615	0.385
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.615	0.385
M51.4 Schmorl's nodes	0.615	0.385
T91.1 Sequelae of fracture of spine	0.614	0.386
Y40 Systemic antibiotics	0.614	0.386
S65.0 Injury of ulnar artery at wrist and hand level	0.614	0.386
S46.2 Injury of muscle and tendon of other parts of biceps	0.614	0.386
O60-O75 Complications of labour and delivery	0.613	0.387
F31.0 Bipolar affective disorder, current episode hypomanic	0.613	0.387
B97 Viral agents as the cause of diseases classified to other chapters	0.612	0.388
L10-L14 Bullous disorders	0.612	0.388
M25.76 Osteophyte (Lower leg)	0.612	0.388
T78.1 Other adverse food reactions, not elsewhere classified	0.612	0.388
F22 Persistent delusional disorders	0.612	0.388
T78.9 Adverse effect, unspecified	0.612	0.388
T78.8 Other adverse effects, not elsewhere classified	0.612	0.388
L60.2 Onychogryphosis	0.611	0.389
H92 Otalgia and effusion of ear	0.611	0.389
L00-L08 Infections of the skin and subcutaneous tissue	0.611	0.389
M25.06 Haemarthrosis (Lower leg)	0.611	0.389
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.609	0.391
S37 Injury of urinary and pelvic organs	0.609	0.391
S36 Injury of intra-abdominal organs	0.609	0.391
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.609	0.391
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.609	0.391
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.609	0.391
S31 Open wound of abdomen, lower back and pelvis	0.609	0.391
F01 Vascular dementia	0.608	0.392
S92.0 Fracture of calcaneus	0.608	0.392
F81.9 Developmental disorder of scholastic skills, unspecified	0.607	0.393

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations