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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62085423
log Bayes Factor = 13.4303
Chromosome 18   position 4,459,889  (GRCh37) Explore rs62085423 on Ensembl!
Variant rs62085423 is part of Cluster X0030

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
G40-G47 Episodic and paroxysmal disorders
0.998 0.002 0.000
M45-M49 Spondylopathies
0.994 0.006 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.988 0.012 0.000
G47 Sleep disorders
0.987 0.013 0.000
J30-J39 Other diseases of upper respiratory tract
0.987 0.013 0.000
C15-C26 Malignant neoplasms of digestive organs
0.985 0.015 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.980 0.020 0.000
J32 Chronic sinusitis
0.977 0.023 0.000
E65-E68 Obesity and other hyperalimentation
0.975 0.025 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.966 0.034 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.964 0.036 0.000
J40 Bronchitis, not specified as acute or chronic
0.964 0.036 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.964 0.036 0.000
E10-E14 Diabetes mellitus
0.963 0.037 0.000
G47.3 Sleep apnoea
0.959 0.041 0.000
E66 Obesity
0.958 0.042 0.000
M48 Other spondylopathies
0.956 0.044 0.000
J32.9 Chronic sinusitis, unspecified
0.954 0.046 0.000
M80-M85 Disorders of bone density and structure
0.954 0.046 0.000
J44 Other chronic obstructive pulmonary disease
0.954 0.046 0.000
I60-I69 Cerebrovascular diseases
0.952 0.048 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.950 0.050 0.000
D50-D53 Nutritional anaemias
0.945 0.055 0.000
Chapter XI Diseases of the digestive system
0.941 0.059 0.000
D51 Vitamin B12 deficiency anaemia
0.936 0.064 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.933 0.067 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.930 0.070 0.000
C64-C68 Malignant neoplasms of urinary tract
0.929 0.071 0.000
M48.0 Spinal stenosis
0.929 0.071 0.000
C79 Secondary malignant neoplasm of other sites
0.927 0.073 0.000
E66.8 Other obesity
0.923 0.077 0.000
J45 Asthma
0.922 0.078 0.000
J09-J18 Influenza and pneumonia
0.921 0.079 0.000
G90-G99 Other disorders of the nervous system
0.920 0.080 0.000
I10-I15 Hypertensive diseases
0.911 0.089 0.000
I63 Cerebral infarction
0.900 0.100 0.000
M50-M54 Other dorsopathies
0.895 0.105 0.000
C18 Malignant neoplasm of colon
0.895 0.105 0.000
M47 Spondylosis
0.893 0.107 0.000
E11 Non-insulin-dependent diabetes mellitus
0.893 0.107 0.000
C20 Malignant neoplasm of rectum
0.891 0.109 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.889 0.111 0.000
C78.7 Secondary malignant neoplasm of liver
0.884 0.116 0.000
J32.0 Chronic maxillary sinusitis
0.883 0.117 0.000
K90-K93 Other diseases of the digestive system
0.882 0.117 0.000
M48.02 Spinal stenosis (Cervical region)
0.870 0.130 0.000
C78.0 Secondary malignant neoplasm of lung
0.870 0.130 0.000
M84 Disorders of continuity of bone
0.870 0.130 0.000
J18 Pneumonia, organism unspecified
0.868 0.132 0.000
E10 Insulin-dependent diabetes mellitus
0.868 0.132 0.000
M81 Osteoporosis without pathological fracture
0.865 0.135 0.000
E66.9 Obesity, unspecified
0.863 0.137 0.000
J47 Bronchiectasis
0.858 0.142 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.858 0.142 0.000
I05-I09 Chronic rheumatic heart diseases
0.858 0.142 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.856 0.144 0.000
M46 Other inflammatory spondylopathies
0.855 0.145 0.000
J18.1 Lobar pneumonia, unspecified
0.854 0.146 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.854 0.146 0.000
Chapter V Mental and behavioural disorders
0.853 0.147 0.000
I77 Other disorders of arteries and arterioles
0.853 0.147 0.000
I70 Atherosclerosis
0.853 0.147 0.000
I27 Other pulmonary heart diseases
0.853 0.147 0.000
K92 Other diseases of digestive system
0.851 0.149 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.851 0.149 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.851 0.149 0.000
M20-M25 Other joint disorders
0.851 0.149 0.000
G30-G32 Other degenerative diseases of the nervous system
0.850 0.150 0.000
E70-E90 Metabolic disorders
0.845 0.155 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.845 0.155 0.000
G47.9 Sleep disorder, unspecified
0.841 0.159 0.000
C23 Malignant neoplasm of gallbladder
0.841 0.159 0.000
J45.0 Predominantly allergic asthma
0.839 0.161 0.000
K70-K77 Diseases of liver
0.837 0.163 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.833 0.167 0.000
I12 Hypertensive renal disease
0.831 0.169 0.000
M47.8 Other spondylosis
0.825 0.175 0.000
K92.0 Haematemesis
0.819 0.181 0.000
M48.09 Spinal stenosis (Site unspecified)
0.819 0.181 0.000
K01 Embedded and impacted teeth
0.815 0.185 0.000
M51 Other intervertebral disk disorders
0.813 0.187 0.000
E50-E64 Other nutritional deficiencies
0.812 0.188 0.000
G70-G73 Diseases of myoneural junction and muscle
0.812 0.188 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.811 0.189 0.000
J30 Vasomotor and allergic rhinitis
0.810 0.189 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.810 0.190 0.000
M45 Ankylosing spondylitis
0.809 0.191 0.000
E10.9 Without complications
0.807 0.193 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.804 0.196 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.802 0.198 0.000
M81.9 Osteoporosis, unspecified
0.801 0.199 0.000
M86-M90 Other osteopathies
0.799 0.201 0.000
G41 Status epilepticus
0.797 0.203 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.796 0.204 0.000
I69 Sequelae of cerebrovascular disease
0.795 0.205 0.000
I63.9 Cerebral infarction, unspecified
0.793 0.207 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.793 0.207 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.792 0.208 0.000
I74 Arterial embolism and thrombosis
0.789 0.211 0.000
I27.2 Other secondary pulmonary hypertension
0.787 0.213 0.000
E20-E35 Disorders of other endocrine glands
0.787 0.213 0.000
G20-G26 Extrapyramidal and movement disorders
0.786 0.214 0.000
I65.2 Occlusion and stenosis of carotid artery
0.785 0.215 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.783 0.217 0.000
E11.3 With ophthalmic complications
0.782 0.218 0.000
J46 Status asthmaticus
0.781 0.219 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.781 0.219 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.780 0.220 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.779 0.221 0.000
I26 Pulmonary embolism
0.779 0.221 0.000
D60-D64 Aplastic and other anaemias
0.779 0.221 0.000
K01.1 Impacted teeth
0.778 0.222 0.000
Chapter XXII Codes for special purposes
0.775 0.225 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.773 0.227 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.772 0.228 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.769 0.230 0.000
J84 Other interstitial pulmonary diseases
0.769 0.231 0.000
C25 Malignant neoplasm of pancreas
0.769 0.231 0.000
C21 Malignant neoplasm of anus and anal canal
0.766 0.234 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.766 0.234 0.000
G93 Other disorders of brain
0.765 0.235 0.000
C79.2 Secondary malignant neoplasm of skin
0.765 0.235 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.765 0.235 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.764 0.236 0.000
E11.5 With peripheral circulatory complications
0.762 0.238 0.000
M65-M68 Disorders of synovium and tendon
0.761 0.239 0.000
M50 Cervical disk disorders
0.759 0.241 0.000
E11.6 With other specified complications
0.757 0.243 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.756 0.244 0.000
M00-M03 Infectious arthropathies
0.755 0.245 0.000
C80 Malignant neoplasm without specification of site
0.754 0.246 0.000
C18.7 Sigmoid colon
0.753 0.247 0.000
C66 Malignant neoplasm of ureter
0.752 0.248 0.000
C18.3 Hepatic flexure
0.751 0.249 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.751 0.249 0.000
I12.0 Hypertensive renal disease with renal failure
0.749 0.251 0.000
C65 Malignant neoplasm of renal pelvis
0.748 0.252 0.000
J45.9 Asthma, unspecified
0.748 0.252 0.000
I08 Multiple valve diseases
0.747 0.253 0.000
M24 Other specific joint derangements
0.746 0.254 0.000
G45.4 Transient global amnesia
0.746 0.254 0.000
K92.1 Melaena
0.745 0.255 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.743 0.256 0.000
D52 Folate deficiency anaemia
0.743 0.257 0.000
M20 Acquired deformities of fingers and toes
0.743 0.257 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.742 0.258 0.000
J60-J70 Lung diseases due to external agents
0.741 0.259 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.740 0.260 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.740 0.260 0.000
G96 Other disorders of central nervous system
0.740 0.260 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.736 0.264 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.734 0.266 0.000
I72 Other aneurysm
0.733 0.267 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.732 0.268 0.000
J39 Other diseases of upper respiratory tract
0.730 0.270 0.000
I78 Diseases of capillaries
0.727 0.273 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.726 0.274 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.726 0.274 0.000
E11.2 With renal complications
0.725 0.275 0.000
I77.1 Stricture of artery
0.725 0.275 0.000
K76 Other diseases of liver
0.724 0.276 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.724 0.276 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.723 0.277 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.721 0.279 0.000
K90 Intestinal malabsorption
0.720 0.280 0.000
K82 Other diseases of gallbladder
0.720 0.280 0.000
C67 Malignant neoplasm of bladder
0.719 0.281 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
G40 Epilepsy
0.717 0.283 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.716 0.284 0.000
K35-K38 Diseases of appendix
0.715 0.285 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.714 0.286 0.000
M51.2 Other specified intervertebral disk displacement
0.714 0.286 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.713 0.287 0.000
M91-M94 Chondropathies
0.713 0.287 0.000
J90-J94 Other diseases of pleura
0.713 0.287 0.000
I61 Intracerebral haemorrhage
0.713 0.287 0.000
M49 Spondylopathies in diseases classified elsewhere
0.712 0.288 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.711 0.289 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.711 0.289 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.710 0.290 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.708 0.292 0.000
C79.6 Secondary malignant neoplasm of ovary
0.708 0.292 0.000
G47.8 Other sleep disorders
0.708 0.292 0.000
G47.4 Narcolepsy and cataplexy
0.708 0.292 0.000
G47.2 Disorders of the sleep-wake schedule
0.708 0.292 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.708 0.292 0.000
J37 Chronic laryngitis and laryngotracheitis
0.708 0.292 0.000
G81 Hemiplegia
0.708 0.292 0.000
D46 Myelodysplastic syndromes
0.707 0.292 0.000
G90 Disorders of autonomic nervous system
0.707 0.293 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.706 0.294 0.000
C17 Malignant neoplasm of small intestine
0.706 0.294 0.000
I10 Essential (primary) hypertension
0.706 0.294 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.705 0.294 0.000
C18.2 Ascending colon
0.704 0.296 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.704 0.296 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.704 0.296 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.704 0.296 0.000
G95 Other diseases of spinal cord
0.703 0.297 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.702 0.298 0.000
G45.3 Amaurosis fugax
0.702 0.298 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.702 0.298 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.702 0.298 0.000
G45.0 Vertebro-basilar artery syndrome
0.702 0.298 0.000
J42 Unspecified chronic bronchitis
0.702 0.298 0.000
Chapter VIII Diseases of the ear and mastoid process
0.701 0.299 0.000
J32.8 Other chronic sinusitis
0.700 0.300 0.000
J32.4 Chronic pansinusitis
0.700 0.300 0.000
J32.3 Chronic sphenoidal sinusitis
0.700 0.300 0.000
J32.2 Chronic ethmoidal sinusitis
0.700 0.300 0.000
J32.1 Chronic frontal sinusitis
0.700 0.300 0.000
M47.82 Other spondylosis (Cervical region)
0.699 0.301 0.000
E67 Other hyperalimentation
0.699 0.301 0.000
E68 Sequelae of hyperalimentation
0.699 0.301 0.000
E65 Localised adiposity
0.699 0.301 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.698 0.302 0.000
M22 Disorders of patella
0.695 0.305 0.000
M21 Other acquired deformities of limbs
0.694 0.306 0.000
K05 Gingivitis and periodontal diseases
0.693 0.306 0.000
J34 Other disorders of nose and nasal sinuses
0.693 0.307 0.000
E14 Unspecified diabetes mellitus
0.692 0.308 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.691 0.309 0.000
D55-D59 Haemolytic anaemias
0.691 0.309 0.000
E12 Malnutrition-related diabetes mellitus
0.691 0.309 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.690 0.310 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.689 0.311 0.000
E10.2 With renal complications
0.689 0.311 0.000
D80-D89 Certain disorders involving the immune mechanism
0.688 0.312 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.688 0.312 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.687 0.313 0.000
E66.1 Drug-induced obesity
0.687 0.313 0.000
E66.0 Obesity due to excess calories
0.687 0.313 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.686 0.314 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.685 0.315 0.000
M48.9 Spondylopathy, unspecified
0.685 0.315 0.000
M48.8 Other specified spondylopathies
0.685 0.315 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.685 0.315 0.000
M48.4 Fatigue fracture of vertebra
0.685 0.315 0.000
M48.3 Traumatic spondylopathy
0.685 0.315 0.000
M48.2 Kissing spine
0.685 0.315 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.685 0.315 0.000
E13 Other specified diabetes mellitus
0.685 0.315 0.000
M83 Adult osteomalacia
0.684 0.316 0.000
M82 Osteoporosis in diseases classified elsewhere
0.684 0.316 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.684 0.316 0.000
J30.1 Allergic rhinitis due to pollen
0.684 0.316 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.683 0.317 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.682 0.317 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.682 0.317 0.000
I62 Other nontraumatic intracranial haemorrhage
0.682 0.317 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.682 0.318 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.681 0.319 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.681 0.319 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.681 0.319 0.000
Chapter XXI Factors influencing health status and contact with health services
0.679 0.321 0.000
K12 Stomatitis and related lesions
0.678 0.321 0.000
D53 Other nutritional anaemias
0.677 0.322 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.677 0.322 0.000
C78.2 Secondary malignant neoplasm of pleura
0.676 0.323 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.677 0.323 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.676 0.324 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.675 0.325 0.000
K75 Other inflammatory liver diseases
0.675 0.325 0.000
M47.89 Other spondylosis (Site unspecified)
0.673 0.327 0.000
C16 Malignant neoplasm of stomach
0.673 0.327 0.000
K55-K64 Other diseases of intestines
0.672 0.328 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.671 0.329 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.671 0.329 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.671 0.329 0.000
D51.2 Transcobalamin II deficiency
0.671 0.329 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.671 0.329 0.000
I28 Other diseases of pulmonary vessels
0.669 0.331 0.000
J31.0 Chronic rhinitis
0.669 0.331 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.669 0.331 0.000
I12.9 Hypertensive renal disease without renal failure
0.668 0.332 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.666 0.334 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.666 0.334 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.666 0.334 0.000
M48.04 Spinal stenosis (Thoracic region)
0.666 0.334 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.666 0.334 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.666 0.334 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.666 0.334 0.000
C18.4 Transverse colon
0.665 0.335 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.665 0.335 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.665 0.335 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.665 0.335 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.665 0.335 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.665 0.335 0.000
Chapter VII Diseases of the eye and adnexa
0.664 0.336 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.663 0.337 0.000
M85 Other disorders of bone density and structure
0.663 0.337 0.000
M80 Osteoporosis with pathological fracture
0.661 0.338 0.000
J45.8 Mixed asthma
0.661 0.339 0.000
J45.1 Nonallergic asthma
0.661 0.339 0.000
J17 Pneumonia in diseases classified elsewhere
0.660 0.340 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.660 0.340 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.660 0.340 0.000
J12 Viral pneumonia, not elsewhere classified
0.660 0.340 0.000
J11 Influenza, virus not identified
0.660 0.340 0.000
J10 Influenza due to identified influenza virus
0.660 0.340 0.000
J14 Pneumonia due to Haemophilus influenzae
0.660 0.340 0.000
J09 Influenza due to certain identified influenza virus
0.660 0.340 0.000
G30 Alzheimer's disease
0.660 0.340 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.660 0.340 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.660 0.340 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.660 0.340 0.000
G92 Toxic encephalopathy
0.660 0.340 0.000
G82 Paraplegia and tetraplegia
0.658 0.342 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.657 0.343 0.000
G71 Primary disorders of muscles
0.654 0.346 0.000
C43 Malignant melanoma of skin
0.653 0.347 0.000
G41.9 Status epilepticus, unspecified
0.653 0.347 0.000
I15 Secondary hypertension
0.653 0.347 0.000
I13 Hypertensive heart and renal disease
0.653 0.347 0.000
I11 Hypertensive heart disease
0.653 0.347 0.000
M24.1 Other articular cartilage disorders
0.652 0.348 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.651 0.349 0.000
E73 Lactose intolerance
0.650 0.350 0.000
K02 Dental caries
0.650 0.350 0.000
I77.8 Other specified disorders of arteries and arterioles
0.650 0.350 0.000
K74 Fibrosis and cirrhosis of liver
0.648 0.352 0.000
I05 Rheumatic mitral valve diseases
0.648 0.352 0.000
K14 Diseases of tongue
0.648 0.352 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.648 0.352 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.648 0.352 0.000
J38.1 Polyp of vocal cord and larynx
0.647 0.353 0.000
G91 Hydrocephalus
0.647 0.353 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.647 0.353 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.647 0.353 0.000
I60 Subarachnoid haemorrhage
0.647 0.353 0.000
J36 Peritonsillar abscess
0.646 0.354 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.645 0.355 0.000
I63.8 Other cerebral infarction
0.645 0.355 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.645 0.355 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.645 0.355 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.645 0.355 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.645 0.355 0.000
J00-J06 Acute upper respiratory infections
0.644 0.355 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.644 0.356 0.000
M40-M43 Deforming dorsopathies
0.644 0.356 0.000
K82.8 Other specified diseases of gallbladder
0.643 0.357 0.000
M47.9 Spondylosis, unspecified
0.643 0.357 0.000
I27.0 Primary pulmonary hypertension
0.642 0.358 0.000
K81 Cholecystitis
0.642 0.358 0.000
M53 Other dorsopathies, not elsewhere classified
0.642 0.358 0.000
C18.8 Overlapping lesion of colon
0.641 0.358 0.000
C18.6 Descending colon
0.641 0.358 0.000
C18.5 Splenic flexure
0.641 0.358 0.000
C18.1 Appendix
0.641 0.358 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.641 0.359 0.000
I71 Aortic aneurysm and dissection
0.641 0.359 0.000
M47.1 Other spondylosis with myelopathy
0.640 0.359 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.640 0.359 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.640 0.360 0.000
E11.8 With unspecified complications
0.640 0.360 0.000
E11.7 With multiple complications
0.640 0.360 0.000
E11.1 With ketoacidosis
0.640 0.360 0.000
E11.0 With coma
0.640 0.360 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.640 0.360 0.000
E61 Deficiency of other nutrient elements
0.640 0.360 0.000
J35 Chronic diseases of tonsils and adenoids
0.638 0.361 0.000
M99 Biomechanical lesions, not elsewhere classified
0.637 0.363 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.637 0.363 0.000
K01.0 Embedded teeth
0.636 0.364 0.000
H53-H54 Visual disturbances and blindness
0.636 0.364 0.000
K13 Other diseases of lip and oral mucosa
0.636 0.364 0.000
G44 Other headache syndromes
0.635 0.365 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.635 0.365 0.000
G93.0 Cerebral cysts
0.634 0.366 0.000
M50.3 Other cervical disk degeneration
0.634 0.366 0.000
F60-F69 Disorders of adult personality and behaviour
0.634 0.366 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.633 0.367 0.000
K09 Cysts of oral region, not elsewhere classified
0.632 0.367 0.000
C25.9 Pancreas, unspecified
0.632 0.368 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.632 0.368 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.631 0.369 0.000
E86 Volume depletion
0.631 0.369 0.000
E53 Deficiency of other B group vitamins
0.629 0.371 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.629 0.371 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.629 0.371 0.000
F99-F99 Unspecified mental disorder
0.627 0.373 0.000
G80 Infantile cerebral palsy
0.626 0.374 0.000
M47.2 Other spondylosis with radiculopathy
0.626 0.374 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.626 0.374 0.000
C18.0 Caecum
0.625 0.375 0.000
M50.1 Cervical disk disorder with radiculopathy
0.625 0.375 0.000
D48.1 Connective and other soft tissue
0.625 0.375 0.000
E10.1 With ketoacidosis
0.625 0.375 0.000
G24 Dystonia
0.624 0.376 0.000
M84.9 Disorder of continuity of bone, unspecified
0.624 0.376 0.000
M84.8 Other disorders of continuity of bone
0.624 0.376 0.000
M84.4 Pathological fracture, not elsewhere classified
0.624 0.376 0.000
M84.3 Stress fracture, not elsewhere classified
0.624 0.376 0.000
M84.2 Delayed union of fracture
0.624 0.376 0.000
M84.0 Malunion of fracture
0.624 0.376 0.000
J18.8 Other pneumonia, organism unspecified
0.623 0.377 0.000
J18.2 Hypostatic pneumonia, unspecified
0.623 0.377 0.000
E10.8 With unspecified complications
0.622 0.377 0.000
E10.7 With multiple complications
0.622 0.377 0.000
E10.6 With other specified complications
0.622 0.377 0.000
E10.5 With peripheral circulatory complications
0.622 0.377 0.000
E10.0 With coma
0.622 0.377 0.000
M20.3 Other deformity of hallux (acquired)
0.622 0.378 0.000
M05-M14 Inflammatory polyarthropathies
0.621 0.379 0.000
M81.8 Other osteoporosis
0.620 0.380 0.000
M81.6 Localised osteoporosis [Lequesne]
0.620 0.380 0.000
M81.5 Idiopathic osteoporosis
0.620 0.380 0.000
M81.4 Drug-induced osteoporosis
0.620 0.380 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.620 0.380 0.000
M81.2 Osteoporosis of disuse
0.620 0.380 0.000
M81.1 Postoophorectomy osteoporosis
0.620 0.380 0.000
M81.0 Postmenopausal osteoporosis
0.620 0.380 0.000
D00-D09 In situ neoplasms
0.620 0.380 0.000
M89 Other disorders of bone
0.619 0.380 0.000
D64 Other anaemias
0.619 0.381 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.618 0.382 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.617 0.383 0.000
M20.4 Other hammer toe(s) (acquired)
0.617 0.383 0.000
K60 Fissure and fistula of anal and rectal regions
0.617 0.383 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.616 0.384 0.000
G70 Myasthenia gravis and other myoneural disorders
0.616 0.384 0.000
I09 Other rheumatic heart diseases
0.615 0.385 0.000
I06 Rheumatic aortic valve diseases
0.615 0.385 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.615 0.385 0.000
C18.9 Colon, unspecified
0.615 0.385 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.614 0.386 0.000
K90.9 Intestinal malabsorption, unspecified
0.614 0.386 0.000
J18.0 Bronchopneumonia, unspecified
0.614 0.386 0.000
K03 Other diseases of hard tissues of teeth
0.614 0.386 0.000
K00 Disorders of tooth development and eruption
0.614 0.386 0.000
D61 Other aplastic anaemias
0.613 0.386 0.000
M46.8 Other specified inflammatory spondylopathies
0.613 0.387 0.000
M46.5 Other infective spondylopathies
0.613 0.387 0.000
M46.4 Discitis, unspecified
0.613 0.387 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.613 0.387 0.000
M46.2 Osteomyelitis of vertebra
0.613 0.387 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.613 0.387 0.000
M46.0 Spinal enthesopathy
0.613 0.387 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.613 0.387 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.613 0.387 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.613 0.387 0.000
I65.1 Occlusion and stenosis of basilar artery
0.613 0.387 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.613 0.387 0.000
K82.2 Perforation of gallbladder
0.613 0.387 0.000
M20.2 Hallux rigidus
0.613 0.387 0.000
J95-J99 Other diseases of the respiratory system
0.612 0.388 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.612 0.388 0.000
F80-F89 Disorders of psychological development
0.612 0.388 0.000
F70-F79 Mental retardation
0.612 0.388 0.000
I77.5 Necrosis of artery
0.612 0.388 0.000
I77.4 Coeliac artery compression syndrome
0.612 0.388 0.000
I77.3 Arterial fibromuscular dysplasia
0.612 0.388 0.000
I77.2 Rupture of artery
0.612 0.388 0.000
I77.0 Arteriovenous fistula, acquired
0.612 0.388 0.000
I70.9 Generalised and unspecified atherosclerosis
0.611 0.388 0.000
I70.8 Atherosclerosis of other arteries
0.611 0.388 0.000
I70.1 Atherosclerosis of renal artery
0.611 0.388 0.000
I70.0 Atherosclerosis of aorta
0.611 0.388 0.000
I27.9 Pulmonary heart disease, unspecified
0.611 0.388 0.000
I27.8 Other specified pulmonary heart diseases
0.611 0.388 0.000
I27.1 Kyphoscoliotic heart disease
0.611 0.388 0.000
Chapter XX External causes of morbidity and mortality
0.611 0.389 0.000
K92.8 Other specified diseases of digestive system
0.610 0.390 0.000
G96.0 Cerebrospinal fluid leak
0.610 0.390 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.610 0.390 0.000
J80 Adult respiratory distress syndrome
0.610 0.390 0.000
G83 Other paralytic syndromes
0.610 0.390 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.610 0.390 0.000
M34 Systemic sclerosis
0.610 0.390 0.000
M33 Dermatopolymyositis
0.610 0.390 0.000
M32 Systemic lupus erythematosus
0.610 0.390 0.000
M30 Polyarteritis nodosa and related conditions
0.610 0.390 0.000
C21.0 Anus, unspecified
0.609 0.391 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.609 0.391 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.609 0.391 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.608 0.392 0.000
E24 Cushing's syndrome
0.608 0.392 0.000
M81.98 Osteoporosis, unspecified (Other)
0.607 0.393 0.000
C80.9 Malignant neoplasm, unspecified
0.607 0.393 0.000
M67 Other disorders of synovium and tendon
0.607 0.393 0.000
J20-J22 Other acute lower respiratory infections
0.607 0.393 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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