TreeWAS – Variant ID: rs62086354

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
I25 Chronic ischaemic heart disease	0.997	0.003
G80-G83 Cerebral palsy and other paralytic syndromes	0.996	0.004
G81 Hemiplegia	0.992	0.008
I70-I79 Diseases of arteries, arterioles and capillaries	0.991	0.009
G81.9 Hemiplegia, unspecified	0.989	0.011
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.988	0.012
I77 Other disorders of arteries and arterioles	0.987	0.013
Chapter XX External causes of morbidity and mortality	0.986	0.014
S00-S09 Injuries to the head	0.976	0.024
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.973	0.027
G50-G59 Nerve, nerve root and plexus disorders	0.970	0.030
Chapter V Mental and behavioural disorders	0.969	0.031
G57 Mononeuropathies of lower limb	0.969	0.031
I22 Subsequent myocardial infarction	0.967	0.033
G57.6 Lesion of plantar nerve	0.966	0.034
S00 Superficial injury of head	0.966	0.034
I25.2 Old myocardial infarction	0.961	0.039
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.959	0.041
T66-T78 Other and unspecified effects of external causes	0.953	0.047
F10 Mental and behavioural disorders due to use of alcohol	0.951	0.049
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.951	0.049
I77.9 Disorder of arteries and arterioles, unspecified	0.944	0.056
Chapter VII Diseases of the eye and adnexa	0.939	0.061
S00.8 Superficial injury of other parts of head	0.935	0.065
I20 Angina pectoris	0.933	0.067
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.921	0.079
I10-I15 Hypertensive diseases	0.914	0.086
T91 Sequelae of injuries of neck and trunk	0.911	0.089
T78 Adverse effects, not elsewhere classified	0.905	0.095
I20.8 Other forms of angina pectoris	0.904	0.096
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.903	0.097
H43-H45 Disorders of vitreous body and globe	0.903	0.097
I77.1 Stricture of artery	0.902	0.098
F10.2 Dependence syndrome	0.901	0.099
I22.9 Subsequent myocardial infarction of unspecified site	0.900	0.100
I25.8 Other forms of chronic ischaemic heart disease	0.898	0.102
I12 Hypertensive renal disease	0.898	0.102
I60-I69 Cerebrovascular diseases	0.891	0.109
I12.0 Hypertensive renal disease with renal failure	0.886	0.114
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.884	0.116
S00.1 Contusion of eyelid and periocular area	0.881	0.119
G70-G73 Diseases of myoneural junction and muscle	0.876	0.124
S06 Intracranial injury	0.874	0.126
S40-S49 Injuries to the shoulder and upper arm	0.873	0.127
I25.3 Aneurysm of heart	0.872	0.128
Y40 Systemic antibiotics	0.871	0.129
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.868	0.132
I25.1 Atherosclerotic heart disease	0.863	0.137
I25.5 Ischaemic cardiomyopathy	0.862	0.138
F10.3 Withdrawal state	0.862	0.138
I77.8 Other specified disorders of arteries and arterioles	0.860	0.140
R30-R39 Symptoms and signs involving the urinary system	0.855	0.145
R32 Unspecified urinary incontinence	0.855	0.145
S20-S29 Injuries to the thorax	0.854	0.146
T20-T25 Burns and corrosions of external body surface, specified by site	0.854	0.146
H43 Disorders of vitreous body	0.852	0.148
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.852	0.148
Y52 Agents primarily affecting the cardiovascular system	0.851	0.149
F10.0 Acute intoxication	0.850	0.150
G00-G09 Inflammatory diseases of the central nervous system	0.850	0.150
Q38-Q45 Other congenital malformations of the digestive system	0.850	0.150
X58-X59 Accidental exposure to other and unspecified factors	0.848	0.152
I77.6 Arteritis, unspecified	0.844	0.156
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.843	0.157
T36-T50 Poisoning by drugs, medicaments and biological substances	0.840	0.160
V01-V09 Pedestrian injured in transport accident	0.836	0.164
Q20-Q28 Congenital malformations of the circulatory system	0.835	0.165
G59 Mononeuropathy in diseases classified elsewhere	0.835	0.165
I74 Arterial embolism and thrombosis	0.831	0.169
I24 Other acute ischaemic heart diseases	0.830	0.170
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.829	0.171
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.826	0.174
Chapter XIV Diseases of the genitourinary system	0.826	0.174
Q80-Q89 Other congenital malformations	0.824	0.176
W50-W64 Exposure to animate mechanical forces	0.823	0.177
I22.0 Subsequent myocardial infarction of anterior wall	0.822	0.178
S00.0 Superficial injury of scalp	0.822	0.178
T98 Sequelae of other and unspecified effects of external causes	0.821	0.179
G82 Paraplegia and tetraplegia	0.820	0.180
G50 Disorders of trigeminal nerve	0.820	0.180
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.817	0.183
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.817	0.183
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.815	0.185
Y40.0 Penicillins	0.814	0.186
I22.1 Subsequent myocardial infarction of inferior wall	0.814	0.186
I72 Other aneurysm	0.814	0.186
I30-I52 Other forms of heart disease	0.812	0.188
N17-N19 Renal failure	0.810	0.190
H25-H28 Disorders of lens	0.809	0.191
I65.2 Occlusion and stenosis of carotid artery	0.807	0.193
T92 Sequelae of injuries of upper limb	0.806	0.194
R21 Rash and other nonspecific skin eruption	0.806	0.194
G57.1 Meralgia paraesthetica	0.803	0.197
I44 Atrioventricular and left bundle-branch block	0.802	0.198
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.801	0.199
F10.4 Withdrawal state with delirium	0.800	0.200
Q00-Q07 Congenital malformations of the nervous system	0.799	0.201
S42 Fracture of shoulder and upper arm	0.792	0.208
G20-G26 Extrapyramidal and movement disorders	0.792	0.208
W20-W49 Exposure to inanimate mechanical forces	0.792	0.208
T95 Sequelae of burns, corrosions and frostbite	0.792	0.208
T78.3 Angioneurotic oedema	0.791	0.209
X50-X57 Overexertion, travel and privation	0.791	0.209
I34 Nonrheumatic mitral valve disorders	0.787	0.213
R47-R49 Symptoms and signs involving speech and voice	0.786	0.214
N17 Acute renal failure	0.785	0.215
S00.4 Superficial injury of ear	0.784	0.216
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.784	0.216
I44.0 Atrioventricular block, first degree	0.783	0.217
H43.8 Other disorders of vitreous body	0.783	0.217
Q66 Congenital deformities of feet	0.781	0.219
T91.8 Sequelae of other specified injuries of neck and trunk	0.781	0.219
Y52.4 Angiotensin-converting-enzyme inhibitors	0.779	0.221
I61 Intracerebral haemorrhage	0.778	0.222
D70-D77 Other diseases of blood and blood-forming organs	0.777	0.223
H44 Disorders of globe	0.775	0.225
Q60-Q64 Congenital malformations of the urinary system	0.775	0.225
I46 Cardiac arrest	0.773	0.227
F20 Schizophrenia	0.769	0.231
I23 Certain current complications following acute myocardial infarction	0.769	0.231
T78.2 Anaphylactic shock, unspecified	0.769	0.231
I25.4 Coronary artery aneurysm	0.768	0.232
N18 Chronic renal failure	0.768	0.232
S05 Injury of eye and orbit	0.767	0.233
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.766	0.234
V40-V49 Car occupant injured in transport accident	0.766	0.234
H25 Senile cataract	0.766	0.234
G57.8 Other mononeuropathies of lower limb	0.765	0.235
S50-S59 Injuries to the elbow and forearm	0.765	0.235
G80 Infantile cerebral palsy	0.763	0.237
Y49 Psychotropic drugs, not elsewhere classified	0.761	0.239
Chapter XXI Factors influencing health status and contact with health services	0.760	0.240
T91.9 Sequelae of unspecified injury of neck and trunk	0.760	0.240
G60 Hereditary and idiopathic neuropathy	0.758	0.242
I34.0 Mitral (valve) insufficiency	0.757	0.243
Q65 Congenital deformities of hip	0.756	0.244
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.755	0.245
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.753	0.247
G62 Other polyneuropathies	0.749	0.251
R47 Speech disturbances, not elsewhere classified	0.749	0.251
Y53 Agents primarily affecting the gastro-intestinal system	0.747	0.252
G70 Myasthenia gravis and other myoneural disorders	0.747	0.253
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.745	0.255
N17.9 Acute renal failure, unspecified	0.745	0.255
I70 Atherosclerosis	0.745	0.255
R40 Somnolence, stupor and coma	0.744	0.256
G61 Inflammatory polyneuropathy	0.744	0.256
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.743	0.257
X20-X29 Contact with venomous animals and plants	0.743	0.257
N18.9 Chronic renal failure, unspecified	0.743	0.257
R47.8 Other and unspecified speech disturbances	0.742	0.258
T78.8 Other adverse effects, not elsewhere classified	0.742	0.258
H52 Disorders of refraction and accommodation	0.741	0.259
I77.0 Arteriovenous fistula, acquired	0.741	0.259
S06.6 Traumatic subarachnoid haemorrhage	0.740	0.260
T68 Hypothermia	0.739	0.261
G59.0 Diabetic mononeuropathy	0.738	0.262
I20.9 Angina pectoris, unspecified	0.737	0.263
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.736	0.264
V10-V19 Pedal cyclist injured in transport accident	0.736	0.264
H25.0 Senile incipient cataract	0.736	0.264
I44.1 Atrioventricular block, second degree	0.736	0.264
N00-N08 Glomerular diseases	0.734	0.266
S10-S19 Injuries to the neck	0.733	0.267
T15-T19 Effects of foreign body entering through natural orifice	0.732	0.268
X40-X49 Accidental poisoning by and exposure to noxious substances	0.730	0.270
V09 Pedestrian injured in other and unspecified transport accidents	0.729	0.271
T91.1 Sequelae of fracture of spine	0.728	0.271
R34 Anuria and oliguria	0.726	0.274
T94 Sequelae of injuries involving multiple and unspecified body regions	0.725	0.275
H55-H59 Other disorders of eye and adnexa	0.720	0.280
Y00-Y09 Assault	0.720	0.280
G63 Polyneuropathy in diseases classified elsewhere	0.718	0.282
S00.2 Other superficial injuries of eyelid and periocular area	0.718	0.282
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
F25 Schizoaffective disorders	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
H25.9 Senile cataract, unspecified	0.717	0.283
R40.2 Coma, unspecified	0.716	0.284
S22 Fracture of rib(s), sternum and thoracic spine	0.715	0.285
I25.6 Silent myocardial ischaemia	0.715	0.285
F23 Acute and transient psychotic disorders	0.715	0.285
T75 Effects of other external causes	0.714	0.286
H43.3 Other vitreous opacities	0.713	0.287
G83 Other paralytic syndromes	0.712	0.288
Q89 Other congenital malformations, not elsewhere classified	0.711	0.289
G81.1 Spastic hemiplegia	0.711	0.289
G81.0 Flaccid hemiplegia	0.711	0.289
Q76 Congenital malformations of spine and bony thorax	0.709	0.290
D73 Diseases of spleen	0.709	0.291
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.708	0.292
Q35-Q37 Cleft lip and cleft palate	0.708	0.292
Q30-Q34 Congenital malformations of the respiratory system	0.708	0.292
F17 Mental and behavioural disorders due to use of tobacco	0.708	0.292
Y47 Sedatives, hypnotics and antianxiety drugs	0.708	0.292
I77.5 Necrosis of artery	0.708	0.292
I77.4 Coeliac artery compression syndrome	0.708	0.292
I77.3 Arterial fibromuscular dysplasia	0.708	0.292
I77.2 Rupture of artery	0.708	0.292
Y48 Anaesthetics and therapeutic gases	0.708	0.292
X10-X19 Contact with heat and hot substances	0.707	0.293
Y35-Y36 Legal intervention and operations of war	0.707	0.293
Y10-Y34 Event of undetermined intent	0.707	0.293
X85-X99 Assault	0.707	0.293
X30-X39 Exposure to forces of nature	0.707	0.293
X00-X09 Exposure to smoke, fire and flames	0.707	0.293
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.707	0.293
W75-W84 Other accidental threats to breathing	0.707	0.293
W65-W74 Accidental drowning and submersion	0.707	0.293
V98-V99 Other and unspecified transport accidents	0.707	0.293
V95-V97 Air and space transport accidents	0.707	0.293
V90-V94 Water transport accidents	0.707	0.293
V70-V79 Bus occupant injured in transport accident	0.707	0.293
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.707	0.293
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.707	0.293
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.707	0.293
Y46 Antiepileptics and anti-Parkinsonism drugs	0.707	0.293
G24 Dystonia	0.706	0.294
H52.1 Myopia	0.705	0.295
S00.9 Superficial injury of head, part unspecified	0.705	0.295
Y60-Y69 Misadventures to patients during surgical and medical care	0.705	0.295
Y41 Other systemic anti-infectives and antiparasitics	0.702	0.298
S60-S69 Injuries to the wrist and hand	0.701	0.299
G50.0 Trigeminal neuralgia	0.701	0.299
S08 Traumatic amputation of part of head	0.700	0.300
S07 Crushing injury of head	0.700	0.300
S04 Injury of cranial nerves	0.700	0.300
S03 Dislocation, sprain and strain of joints and ligaments of head	0.700	0.300
H10-H13 Disorders of conjunctiva	0.699	0.301
Q43 Other congenital malformations of intestine	0.699	0.301
N18.3 Chronic kidney disease, stage 3	0.698	0.302
T91.3 Sequelae of injury of spinal cord	0.698	0.302
D60-D64 Aplastic and other anaemias	0.698	0.302
Q21 Congenital malformations of cardiac septa	0.698	0.302
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.698	0.302
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.698	0.302
S42.0 Fracture of clavicle	0.697	0.303
R45 Symptoms and signs involving emotional state	0.697	0.303
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.697	0.303
R41 Other symptoms and signs involving cognitive functions and awareness	0.696	0.304
T21 Burn and corrosion of trunk	0.696	0.304
I46.9 Cardiac arrest, unspecified	0.696	0.304
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.696	0.304
G52 Disorders of other cranial nerves	0.695	0.305
H46-H48 Disorders of optic nerve and visual pathways	0.695	0.305
N25-N29 Other disorders of kidney and ureter	0.695	0.305
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.695	0.305
F70-F79 Mental retardation	0.695	0.305
Q50-Q56 Congenital malformations of genital organs	0.695	0.305
G57.9 Mononeuropathy of lower limb, unspecified	0.694	0.305
G57.5 Tarsal tunnel syndrome	0.694	0.305
G57.4 Lesion of medial popliteal nerve	0.694	0.305
G57.3 Lesion of lateral popliteal nerve	0.694	0.305
G57.2 Lesion of femoral nerve	0.694	0.305
G57.0 Lesion of sciatic nerve	0.694	0.305
I25.0 Atherosclerotic cardiovascular disease, so described	0.694	0.306
X59 Exposure to unspecified factor	0.694	0.306
X58 Exposure to other specified factors	0.694	0.306
I46.0 Cardiac arrest with successful resuscitation	0.694	0.306
N08 Glomerular disorders in diseases classified elsewhere	0.694	0.306
Q66.8 Other congenital deformities of feet	0.693	0.307
H44.2 Degenerative myopia	0.692	0.308
T78.1 Other adverse food reactions, not elsewhere classified	0.692	0.308
I72.4 Aneurysm of artery of lower extremity	0.691	0.309
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.691	0.309
H21 Other disorders of iris and ciliary body	0.690	0.310
S06.5 Traumatic subdural haemorrhage	0.690	0.310
I62 Other nontraumatic intracranial haemorrhage	0.689	0.310
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.689	0.311
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.689	0.311
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.688	0.312
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.688	0.312
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.688	0.312
F18 Mental and behavioural disorders due to use of volatile solvents	0.688	0.312
F16 Mental and behavioural disorders due to use of hallucinogens	0.688	0.312
F14 Mental and behavioural disorders due to use of cocaine	0.688	0.312
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.688	0.312
Y86 Sequelae of other accidents	0.688	0.312
S27 Injury of other and unspecified intrathoracic organs	0.687	0.313
F60-F69 Disorders of adult personality and behaviour	0.687	0.313
R20 Disturbances of skin sensation	0.686	0.314
G72 Other myopathies	0.686	0.314
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.686	0.314
Y40.1 Cefalosporins and other -lactam antibiotics	0.686	0.314
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.685	0.315
T93 Sequelae of injuries of lower limb	0.685	0.315
I61.9 Intracerebral haemorrhage, unspecified	0.684	0.316
Chapter XXII Codes for special purposes	0.683	0.316
T74 Maltreatment syndromes	0.683	0.317
T73 Effects of other deprivation	0.683	0.317
T70 Effects of air pressure and water pressure	0.683	0.317
T69 Other effects of reduced temperature	0.683	0.317
T67 Effects of heat and light	0.683	0.317
T71 Asphyxiation	0.683	0.317
T66 Unspecified effects of radiation	0.683	0.317
D72 Other disorders of white blood cells	0.683	0.317
I12.9 Hypertensive renal disease without renal failure	0.683	0.317
F10.8 Other mental and behavioural disorders	0.682	0.318
F10.7 Residual and late-onset psychotic disorder	0.682	0.318
F10.6 Amnesic syndrome	0.682	0.318
F10.5 Psychotic disorder	0.682	0.318
F12 Mental and behavioural disorders due to use of cannabinoids	0.682	0.318
Y59 Other and unspecified vaccines and biological substances	0.682	0.318
Y58 Bacterial vaccines	0.682	0.318
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.682	0.318
Y50 Central nervous system stimulants, not elsewhere classified	0.682	0.318
N17.0 Acute renal failure with tubular necrosis	0.680	0.320
N30-N39 Other diseases of urinary system	0.679	0.321
G00 Bacterial meningitis, not elsewhere classified	0.678	0.322
S06.3 Focal brain injury	0.678	0.322
T23 Burn and corrosion of wrist and hand	0.678	0.322
T92.1 Sequelae of fracture of arm	0.678	0.322
Q05 Spina bifida	0.676	0.323
Q61 Cystic kidney disease	0.676	0.324
Y40.9 Systemic antibiotic, unspecified	0.675	0.325
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.675	0.325
X60-X84 Intentional self-harm	0.674	0.326
Y57 Other and unspecified drugs and medicaments	0.674	0.326
G62.8 Other specified polyneuropathies	0.674	0.326
R41.0 Disorientation, unspecified	0.673	0.327
N99-N99 Other disorders of the genitourinary system	0.672	0.328
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.672	0.328
I24.9 Acute ischaemic heart disease, unspecified	0.672	0.328
H20 Iridocyclitis	0.671	0.329
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.671	0.329
N30 Cystitis	0.671	0.329
Q24 Other congenital malformations of heart	0.670	0.330
S06.8 Other intracranial injuries	0.670	0.330
T36 Poisoning by systemic antibiotics	0.669	0.331
F99-F99 Unspecified mental disorder	0.669	0.331
F10.9 Unspecified mental and behavioural disorder	0.668	0.332
S49 Other and unspecified injuries of shoulder and upper arm	0.666	0.334
G82.1 Spastic paraplegia	0.665	0.334
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.665	0.335
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.664	0.335
I44.2 Atrioventricular block, complete	0.664	0.336
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.664	0.336
Chapter I Certain infectious and parasitic diseases	0.663	0.337
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.662	0.338
S90-S99 Injuries to the ankle and foot	0.662	0.338
I69 Sequelae of cerebrovascular disease	0.661	0.339
R36 Urethral discharge	0.661	0.339
G64 Other disorders of peripheral nervous system	0.660	0.340
T98.1 Sequelae of other and unspecified effects of external causes	0.660	0.340
N60-N64 Disorders of breast	0.660	0.340
I74.8 Embolism and thrombosis of other arteries	0.660	0.340
Q39 Congenital malformations of oesophagus	0.660	0.340
S46 Injury of muscle and tendon at shoulder and upper arm level	0.659	0.340
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.659	0.341
I24.8 Other forms of acute ischaemic heart disease	0.658	0.342
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.657	0.343
T78.0 Anaphylactic shock due to adverse food reaction	0.656	0.344
G03 Meningitis due to other and unspecified causes	0.655	0.345
I13 Hypertensive heart and renal disease	0.655	0.345
I11 Hypertensive heart disease	0.655	0.345
G70.0 Myasthenia gravis	0.654	0.346
S29 Other and unspecified injuries of thorax	0.654	0.346
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.654	0.346
G71 Primary disorders of muscles	0.654	0.346
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.653	0.347
T91.4 Sequelae of injury of intrathoracic organs	0.653	0.347
T91.2 Sequelae of other fracture of thorax and pelvis	0.653	0.347
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.653	0.347
I74.9 Embolism and thrombosis of unspecified artery	0.651	0.349
I72.0 Aneurysm of carotid artery	0.651	0.349
Z36 Antenatal screening	0.651	0.349
Y40.3 Macrolides	0.651	0.349
Q65.8 Other congenital deformities of hip	0.651	0.349
I22.8 Subsequent myocardial infarction of other sites	0.651	0.349
F20.9 Schizophrenia, unspecified	0.650	0.350
S22.3 Fracture of rib	0.650	0.350
G53 Cranial nerve disorders in diseases classified elsewhere	0.650	0.350
T78.9 Adverse effect, unspecified	0.649	0.351
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.649	0.351
Q78 Other osteochondrodysplasias	0.648	0.352
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.648	0.352
Q75 Other congenital malformations of skull and face bones	0.648	0.352
Q74 Other congenital malformations of limb(s)	0.648	0.352
Q73 Reduction defects of unspecified limb	0.648	0.352
Q72 Reduction defects of lower limb	0.648	0.352
Q71 Reduction defects of upper limb	0.648	0.352
Q70 Syndactyly	0.648	0.352
Q69 Polydactyly	0.648	0.352
Q68 Other congenital musculoskeletal deformities	0.648	0.352
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.648	0.352
I74.5 Embolism and thrombosis of iliac artery	0.648	0.352
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.647	0.352
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.647	0.353
F30-F39 Mood [affective] disorders	0.646	0.354
R20.8 Other and unspecified disturbances of skin sensation	0.645	0.355
F17.2 Dependence syndrome	0.645	0.355
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.643	0.357
S32 Fracture of lumbar spine and pelvis	0.643	0.357
D50-D53 Nutritional anaemias	0.643	0.357
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.643	0.357
S09 Other and unspecified injuries of head	0.642	0.357
T46 Poisoning by agents primarily affecting the cardiovascular system	0.642	0.358
Q82 Other congenital malformations of skin	0.642	0.358
W51 Striking against or bumped into by another person	0.642	0.358
N64 Other disorders of breast	0.642	0.358
W29 Contact with other powered hand tools and household machinery	0.641	0.359
N08.3 Glomerular disorders in diabetes mellitus	0.641	0.359
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.640	0.360
S70-S79 Injuries to the hip and thigh	0.639	0.361
I68 Cerebrovascular disorders in diseases classified elsewhere	0.639	0.361
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.639	0.361
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.639	0.361
H49 Paralytic strabismus	0.638	0.362
I61.6 Intracerebral haemorrhage, multiple localised	0.636	0.363
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.636	0.364
W44 Foreign body entering into or through eye or natural orifice	0.636	0.364
W55 Bitten or struck by other mammals	0.636	0.364
S06.0 Concussion	0.636	0.364
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.636	0.364
F28 Other nonorganic psychotic disorders	0.634	0.366
F24 Induced delusional disorder	0.634	0.366
F21 Schizotypal disorder	0.634	0.366
S27.0 Traumatic pneumothorax	0.633	0.367
F22 Persistent delusional disorders	0.632	0.368
S60 Superficial injury of wrist and hand	0.631	0.369
H43.1 Vitreous haemorrhage	0.631	0.369
Q89.2 Congenital malformations of other endocrine glands	0.631	0.369
S42.00 Fracture of clavicle (closed)	0.630	0.370
F11 Mental and behavioural disorders due to use of opioids	0.629	0.371
S66 Injury of muscle and tendon at wrist and hand level	0.629	0.371
H21.5 Other adhesions and disruptions of iris and ciliary body	0.629	0.371
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.628	0.372
I20.1 Angina pectoris with documented spasm	0.628	0.372
Q23 Congenital malformations of aortic and mitral valves	0.628	0.372
T78.4 Allergy, unspecified	0.628	0.372
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.628	0.372
S06.9 Intracranial injury, unspecified	0.627	0.373
S06.7 Intracranial injury with prolonged coma	0.627	0.373
S06.1 Traumatic cerebral oedema	0.627	0.373
S48 Traumatic amputation of shoulder and upper arm	0.626	0.374
S45 Injury of blood vessels at shoulder and upper arm level	0.626	0.374
S44 Injury of nerves at shoulder and upper arm level	0.626	0.374
S47 Crushing injury of shoulder and upper arm	0.626	0.374
Y49.5 Other antipsychotics and neuroleptics	0.626	0.374
G01 Meningitis in bacterial diseases classified elsewhere	0.625	0.375
Y40.7 Antifungal antibiotics, systemically used	0.625	0.375
Y40.6 Rifamycins	0.625	0.375
Y40.5 Aminoglycosides	0.625	0.375
Y40.4 Tetracyclines	0.625	0.375
Y40.2 Chloramphenicol group	0.625	0.375
Z70-Z76 Persons encountering health services in other circumstances	0.624	0.376
S00.5 Superficial injury of lip and oral cavity	0.623	0.377
G82.5 Tetraplegia, unspecified	0.623	0.377
R95-R99 Ill-defined and unknown causes of mortality	0.622	0.377
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.622	0.378
N30.8 Other cystitis	0.622	0.378
S41 Open wound of shoulder and upper arm	0.621	0.379
X51 Travel and motion	0.620	0.380
F20.0 Paranoid schizophrenia	0.619	0.381
R39 Other symptoms and signs involving the urinary system	0.619	0.381
I65.0 Occlusion and stenosis of vertebral artery	0.618	0.382
G60.0 Hereditary motor and sensory neuropathy	0.618	0.382
V20-V29 Motorcycle rider injured in transport accident	0.617	0.382
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.617	0.383
V80-V89 Other land transport accidents	0.617	0.383
Q61.3 Polycystic kidney, unspecified	0.617	0.383
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.617	0.383
Y42.2 Antithyroid drugs	0.617	0.383
S42.1 Fracture of scapula	0.616	0.384
Q38 Other congenital malformations of tongue, mouth and pharynx	0.616	0.384
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.616	0.384
S56 Injury of muscle and tendon at forearm level	0.615	0.385
G61.8 Other inflammatory polyneuropathies	0.614	0.386
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.614	0.386
R33 Retention of urine	0.614	0.386
T20 Burn and corrosion of head and neck	0.613	0.387
S40 Superficial injury of shoulder and upper arm	0.613	0.387
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.612	0.387
S26 Injury of heart	0.612	0.387
S25 Injury of blood vessels of thorax	0.612	0.387
S24 Injury of nerves and spinal cord at thorax level	0.612	0.387
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.612	0.387
S21 Open wound of thorax	0.612	0.387
T25 Burn and corrosion of ankle and foot	0.612	0.387
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.612	0.387
G50.1 Atypical facial pain	0.612	0.388
H43.9 Disorder of vitreous body, unspecified	0.611	0.389
H43.2 Crystalline deposits in vitreous body	0.611	0.389
H43.0 Vitreous prolapse	0.611	0.389
H27 Other disorders of lens	0.611	0.389
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.610	0.390
Y52.8 Antivaricose drugs, including sclerosing agents	0.610	0.390
Y52.7 Peripheral vasodilators	0.610	0.390
Y52.1 Calcium-channel blockers	0.610	0.390
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.610	0.390
S06.2 Diffuse brain injury	0.610	0.390
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.609	0.390

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations