TreeWAS – Variant ID: rs62231069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.999	0.001
Chapter XX External causes of morbidity and mortality	0.999	0.001
Chapter XII Diseases of the skin and subcutaneous tissue	0.997	0.003
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.995	0.005
Chapter V Mental and behavioural disorders	0.994	0.006
L60-L75 Disorders of skin appendages	0.994	0.006
L60 Nail disorders	0.986	0.014
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.982	0.018
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.976	0.024
L60.0 Ingrowing nail	0.973	0.027
F30-F39 Mood [affective] disorders	0.973	0.027
W00-W19 Falls	0.970	0.030
S00-S09 Injuries to the head	0.965	0.035
M20-M25 Other joint disorders	0.957	0.043
S20-S29 Injuries to the thorax	0.950	0.050
T39.1 4-Aminophenol derivatives	0.949	0.051
L40-L45 Papulosquamous disorders	0.943	0.057
W19 Unspecified fall	0.940	0.060
F32 Depressive episode	0.938	0.062
S60-S69 Injuries to the wrist and hand	0.934	0.066
L73 Other follicular disorders	0.931	0.069
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.929	0.071
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.925	0.075
M05 Seropositive rheumatoid arthritis	0.921	0.079
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.918	0.082
T46 Poisoning by agents primarily affecting the cardiovascular system	0.917	0.083
M20 Acquired deformities of fingers and toes	0.915	0.085
M65-M68 Disorders of synovium and tendon	0.910	0.090
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.904	0.096
S40-S49 Injuries to the shoulder and upper arm	0.901	0.099
S62 Fracture at wrist and hand level	0.901	0.099
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.896	0.104
S01 Open wound of head	0.895	0.105
W19.9 Unspecified place	0.893	0.107
F32.9 Depressive episode, unspecified	0.892	0.108
M31 Other necrotising vasculopathies	0.885	0.115
S22 Fracture of rib(s), sternum and thoracic spine	0.883	0.117
M20.2 Hallux rigidus	0.879	0.121
L40 Psoriasis	0.878	0.122
L60.8 Other nail disorders	0.875	0.125
Chapter VI Diseases of the nervous system	0.870	0.130
M21 Other acquired deformities of limbs	0.869	0.131
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.869	0.131
S62.6 Fracture of other finger	0.868	0.132
M05.9 Seropositive rheumatoid arthritis, unspecified	0.864	0.136
M86-M90 Other osteopathies	0.864	0.136
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.861	0.139
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.861	0.139
T39.0 Salicylates	0.860	0.140
M20.0 Deformity of finger(s)	0.858	0.142
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.857	0.143
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.853	0.147
F20 Schizophrenia	0.852	0.148
S01.0 Open wound of scalp	0.850	0.150
L40.5 Arthropathic psoriasis	0.849	0.151
L73.9 Follicular disorder, unspecified	0.848	0.152
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.848	0.152
M40-M43 Deforming dorsopathies	0.847	0.153
S22.4 Multiple fractures of ribs	0.843	0.157
W07 Fall involving chair	0.840	0.160
S62.60 Fracture of other finger (closed)	0.839	0.161
S00 Superficial injury of head	0.836	0.164
V40-V49 Car occupant injured in transport accident	0.833	0.167
M67 Other disorders of synovium and tendon	0.826	0.174
Y42.7 Androgens and anabolic congeners	0.826	0.174
F32.2 Severe depressive episode without psychotic symptoms	0.823	0.177
M60-M63 Disorders of muscles	0.823	0.177
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.822	0.178
M24 Other specific joint derangements	0.820	0.180
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.819	0.181
F40-F48 Neurotic, stress-related and somatoform disorders	0.818	0.182
Q20-Q28 Congenital malformations of the circulatory system	0.816	0.184
M31.6 Other giant cell arteritis	0.816	0.184
M06.4 Inflammatory polyarthropathy	0.816	0.184
S22.40 Multiple fractures of ribs (closed)	0.814	0.186
F33 Recurrent depressive disorder	0.811	0.189
F25 Schizoaffective disorders	0.808	0.192
F34 Persistent mood [affective] disorders	0.808	0.192
S09 Other and unspecified injuries of head	0.806	0.194
L50-L54 Urticaria and erythema	0.806	0.194
S90-S99 Injuries to the ankle and foot	0.805	0.194
S49 Other and unspecified injuries of shoulder and upper arm	0.804	0.196
Y54.5 Other diuretics	0.802	0.198
T36 Poisoning by systemic antibiotics	0.799	0.201
G80-G83 Cerebral palsy and other paralytic syndromes	0.797	0.203
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.797	0.203
S01.3 Open wound of ear	0.795	0.205
M20.6 Acquired deformity of toe(s), unspecified	0.793	0.207
Y60-Y69 Misadventures to patients during surgical and medical care	0.789	0.211
L73.2 Hidradenitis suppurativa	0.787	0.213
L43 Lichen planus	0.787	0.213
T46.4 Angiotensin-converting-enzyme inhibitors	0.786	0.214
T46.1 Calcium-channel blockers	0.783	0.217
Y49 Psychotropic drugs, not elsewhere classified	0.783	0.217
Y00-Y09 Assault	0.782	0.218
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.780	0.220
X58-X59 Accidental exposure to other and unspecified factors	0.780	0.220
X60-X84 Intentional self-harm	0.780	0.220
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.777	0.223
S00.0 Superficial injury of scalp	0.777	0.223
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.775	0.225
Y52 Agents primarily affecting the cardiovascular system	0.775	0.225
F20.9 Schizophrenia, unspecified	0.775	0.225
F60-F69 Disorders of adult personality and behaviour	0.774	0.226
S27 Injury of other and unspecified intrathoracic organs	0.774	0.226
W50-W64 Exposure to animate mechanical forces	0.773	0.227
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.773	0.227
W19.4 Street and highway	0.772	0.228
S10-S19 Injuries to the neck	0.771	0.229
V80-V89 Other land transport accidents	0.771	0.229
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.770	0.229
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.770	0.230
T43.5 Other and unspecified antipsychotics and neuroleptics	0.769	0.231
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.769	0.231
W11 Fall on and from ladder	0.767	0.233
X40-X49 Accidental poisoning by and exposure to noxious substances	0.764	0.236
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.763	0.237
M06.0 Seronegative rheumatoid arthritis	0.762	0.238
T50.9 Other and unspecified drugs, medicaments and biological substances	0.762	0.238
S41 Open wound of shoulder and upper arm	0.759	0.241
S68 Traumatic amputation of wrist and hand	0.758	0.242
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.758	0.242
G90-G99 Other disorders of the nervous system	0.757	0.243
Q60-Q64 Congenital malformations of the urinary system	0.755	0.245
W20-W49 Exposure to inanimate mechanical forces	0.753	0.247
W03 Other fall on same level due to collision with, or pushing by, another person	0.753	0.247
M07 Psoriatic and enteropathic arthropathies	0.752	0.248
Chapter VIII Diseases of the ear and mastoid process	0.752	0.248
M41 Scoliosis	0.751	0.249
Y86 Sequelae of other accidents	0.750	0.250
L65 Other nonscarring hair loss	0.747	0.253
F00-F09 Organic, including symptomatic, mental disorders	0.746	0.254
M14 Arthropathies in other diseases classified elsewhere	0.745	0.255
S05 Injury of eye and orbit	0.745	0.255
S60 Superficial injury of wrist and hand	0.743	0.257
S29 Other and unspecified injuries of thorax	0.742	0.258
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.742	0.258
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.740	0.260
T51 Toxic effect of alcohol	0.737	0.263
W07.0 Home	0.736	0.264
M91-M94 Chondropathies	0.736	0.264
S40 Superficial injury of shoulder and upper arm	0.736	0.264
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.736	0.264
S49.9 Unspecified injury of shoulder and upper arm	0.734	0.266
Y45.0 Opioids and related analgesics	0.731	0.269
Chapter XV Pregnancy, childbirth and the puerperium	0.730	0.270
Y40 Systemic antibiotics	0.729	0.271
L71 Rosacea	0.728	0.272
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.728	0.272
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.726	0.274
M89 Other disorders of bone	0.725	0.275
M06.3 Rheumatoid nodule	0.723	0.277
F25.9 Schizoaffective disorder, unspecified	0.721	0.279
Chapter XXII Codes for special purposes	0.720	0.279
Q00-Q07 Congenital malformations of the nervous system	0.720	0.280
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M12 Other specific arthropathies	0.717	0.283
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283
M08 Juvenile arthritis	0.717	0.283
M06.8 Other specified rheumatoid arthritis	0.717	0.283
M06.2 Rheumatoid bursitis	0.717	0.283
M06.1 Adult-onset Still's disease	0.717	0.283
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.716	0.283
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.716	0.283
T41 Poisoning by anaesthetics and therapeutic gases	0.716	0.283
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.716	0.283
Y35-Y36 Legal intervention and operations of war	0.716	0.283
Y10-Y34 Event of undetermined intent	0.716	0.283
X85-X99 Assault	0.716	0.283
X50-X57 Overexertion, travel and privation	0.716	0.283
X30-X39 Exposure to forces of nature	0.716	0.283
X20-X29 Contact with venomous animals and plants	0.716	0.283
X10-X19 Contact with heat and hot substances	0.716	0.283
X00-X09 Exposure to smoke, fire and flames	0.716	0.283
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.283
W75-W84 Other accidental threats to breathing	0.716	0.283
W65-W74 Accidental drowning and submersion	0.716	0.283
V98-V99 Other and unspecified transport accidents	0.716	0.283
V95-V97 Air and space transport accidents	0.716	0.283
V90-V94 Water transport accidents	0.716	0.283
V70-V79 Bus occupant injured in transport accident	0.716	0.283
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.283
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.283
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.283
V01-V09 Pedestrian injured in transport accident	0.716	0.283
T42.4 Benzodiazepines	0.716	0.284
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.716	0.284
M67.8 Other specified disorders of synovium and tendon	0.715	0.284
L10-L14 Bullous disorders	0.715	0.285
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.713	0.287
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.713	0.287
F70-F79 Mental retardation	0.713	0.287
L75 Apocrine sweat disorders	0.712	0.288
L74 Eccrine sweat disorders	0.712	0.288
L70 Acne	0.712	0.288
L68 Hypertrichosis	0.712	0.288
L67 Hair colour and hair shaft abnormalities	0.712	0.288
L66 Cicatricial alopecia [scarring hair loss]	0.712	0.288
L64 Androgenic alopecia	0.712	0.288
L63 Alopecia areata	0.712	0.288
L62 Nail disorders in diseases classified elsewhere	0.712	0.288
M21.3 Wrist or foot drop (acquired)	0.712	0.288
T79-T79 Certain early complications of trauma	0.710	0.290
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.710	0.290
M21.2 Flexion deformity	0.709	0.291
Y48 Anaesthetics and therapeutic gases	0.709	0.291
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.709	0.291
W19.2 School, other institution and public administrative area	0.709	0.291
W19.3 Sports and athletics area	0.708	0.292
F30 Manic episode	0.708	0.292
M11 Other crystal arthropathies	0.707	0.292
L60.9 Nail disorder, unspecified	0.707	0.293
L60.5 Yellow nail syndrome	0.707	0.293
L60.4 Beau's lines	0.707	0.293
L60.3 Nail dystrophy	0.707	0.293
L60.2 Onychogryphosis	0.707	0.293
L60.1 Onycholysis	0.707	0.293
F45 Somatoform disorders	0.707	0.293
Q50-Q56 Congenital malformations of genital organs	0.707	0.293
F32.0 Mild depressive episode	0.706	0.294
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.706	0.294
T42.1 Iminostilbenes	0.706	0.294
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.704	0.296
T39.4 Antirheumatics, not elsewhere classified	0.704	0.296
T39.2 Pyrazolone derivatives	0.704	0.296
G81 Hemiplegia	0.702	0.298
M21.0 Valgus deformity, not elsewhere classified	0.701	0.299
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.700	0.300
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.700	0.300
Y59 Other and unspecified vaccines and biological substances	0.700	0.300
Y58 Bacterial vaccines	0.700	0.300
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.700	0.300
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.700	0.300
Y53 Agents primarily affecting the gastro-intestinal system	0.700	0.300
Y50 Central nervous system stimulants, not elsewhere classified	0.700	0.300
Y47 Sedatives, hypnotics and antianxiety drugs	0.700	0.300
Y46 Antiepileptics and anti-Parkinsonism drugs	0.700	0.300
S62.2 Fracture of first metacarpal bone	0.699	0.301
F43 Reaction to severe stress, and adjustment disorders	0.699	0.301
F38 Other mood [affective] disorders	0.698	0.302
F39 Unspecified mood [affective] disorder	0.698	0.302
W18 Other fall on same level	0.697	0.302
M31.3 Wegener's granulomatosis	0.697	0.303
Q27 Other congenital malformations of peripheral vascular system	0.696	0.304
M62 Other disorders of muscle	0.696	0.304
M66 Spontaneous rupture of synovium and tendon	0.695	0.305
W17 Other fall from one level to another	0.695	0.305
W16 Diving or jumping into water causing injury other than drowning or submersion	0.695	0.305
W15 Fall from cliff	0.695	0.305
W14 Fall from tree	0.695	0.305
W12 Fall on and from scaffolding	0.695	0.305
W09 Fall involving playground equipment	0.695	0.305
W05 Fall involving wheelchair	0.695	0.305
W04 Fall while being carried or supported by other persons	0.695	0.305
W01 Fall on same level from slipping, tripping and stumbling	0.695	0.305
W00 Fall on same level involving ice and snow	0.695	0.305
M24.2 Disorder of ligament	0.695	0.305
M00-M03 Infectious arthropathies	0.695	0.305
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.694	0.305
W08 Fall involving other furniture	0.693	0.307
Y57 Other and unspecified drugs and medicaments	0.693	0.307
S08 Traumatic amputation of part of head	0.692	0.308
S07 Crushing injury of head	0.692	0.308
S04 Injury of cranial nerves	0.692	0.308
S03 Dislocation, sprain and strain of joints and ligaments of head	0.692	0.308
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.692	0.308
S91 Open wound of ankle and foot	0.691	0.309
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.691	0.309
T51.9 Alcohol, unspecified	0.690	0.310
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.689	0.311
W19.1 Residential institution	0.689	0.311
F34.1 Dysthymia	0.689	0.311
S62.5 Fracture of thumb	0.688	0.312
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.686	0.314
M33 Dermatopolymyositis	0.686	0.314
M32 Systemic lupus erythematosus	0.686	0.314
M30 Polyarteritis nodosa and related conditions	0.686	0.314
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.685	0.315
G30-G32 Other degenerative diseases of the nervous system	0.685	0.315
Y44 Agents primarily affecting blood constituents	0.684	0.316
L40.8 Other psoriasis	0.682	0.318
F32.1 Moderate depressive episode	0.682	0.318
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.681	0.319
S26 Injury of heart	0.681	0.319
S25 Injury of blood vessels of thorax	0.681	0.319
S24 Injury of nerves and spinal cord at thorax level	0.681	0.319
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.681	0.319
S21 Open wound of thorax	0.681	0.319
W06 Fall involving bed	0.681	0.319
F20.0 Paranoid schizophrenia	0.680	0.320
S06 Intracranial injury	0.680	0.320
F22 Persistent delusional disorders	0.678	0.322
M65 Synovitis and tenosynovitis	0.677	0.323
L00-L08 Infections of the skin and subcutaneous tissue	0.677	0.323
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.676	0.324
L44 Other papulosquamous disorders	0.676	0.324
L41 Parapsoriasis	0.676	0.324
L45 Papulosquamous disorders in diseases classified elsewhere	0.676	0.324
L42 Pityriasis rosea	0.676	0.324
V10-V19 Pedal cyclist injured in transport accident	0.676	0.324
L43.9 Lichen planus, unspecified	0.675	0.325
W19.8 Other specified place	0.674	0.326
W19.5 Trade and service area	0.674	0.326
W19.0 Home	0.674	0.326
W19.7 Farm	0.674	0.326
W19.6 Industrial and construction area	0.674	0.326
M90 Osteopathies in diseases classified elsewhere	0.674	0.326
F80-F89 Disorders of psychological development	0.674	0.326
V49 Car occupant injured in other and unspecified transport accidents	0.674	0.326
F32.8 Other depressive episodes	0.672	0.328
T56 Toxic effect of metals	0.672	0.328
F33.1 Recurrent depressive disorder, current episode moderate	0.671	0.329
S62.61 Fracture of other finger (open)	0.671	0.329
S09.9 Unspecified injury of head	0.670	0.330
S65 Injury of blood vessels at wrist and hand level	0.670	0.330
S01.7 Multiple open wounds of head	0.669	0.331
M41.9 Scoliosis, unspecified	0.669	0.331
M80-M85 Disorders of bone density and structure	0.668	0.332
S20 Superficial injury of thorax	0.667	0.333
L73.8 Other specified follicular disorders	0.667	0.333
L73.1 Pseudofolliculitis barbae	0.667	0.333
L73.0 Acne keloid	0.667	0.333
F28 Other nonorganic psychotic disorders	0.666	0.334
F24 Induced delusional disorder	0.666	0.334
F21 Schizotypal disorder	0.666	0.334
M67.1 Other contracture of tendon (sheath)	0.663	0.337
G70-G73 Diseases of myoneural junction and muscle	0.663	0.337
S62.8 Fracture of other and unspecified parts of wrist and hand	0.662	0.338
S70-S79 Injuries to the hip and thigh	0.662	0.338
Q23 Congenital malformations of aortic and mitral valves	0.661	0.339
M05.8 Other seropositive rheumatoid arthritis	0.660	0.340
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.660	0.340
M05.2 Rheumatoid vasculitis	0.660	0.340
M05.1 Rheumatoid lung disease	0.660	0.340
M05.0 Felty's syndrome	0.660	0.340
M21.1 Varus deformity, not elsewhere classified	0.660	0.340
T15-T19 Effects of foreign body entering through natural orifice	0.659	0.341
Y45.1 Salicylates	0.659	0.341
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.658	0.342
Q35-Q37 Cleft lip and cleft palate	0.658	0.342
Q30-Q34 Congenital malformations of the respiratory system	0.658	0.342
V20-V29 Motorcycle rider injured in transport accident	0.658	0.342
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.657	0.343
T46.8 Antivaricose drugs, including sclerosing agents	0.657	0.343
T46.7 Peripheral vasodilators	0.657	0.343
T46.5 Other antihypertensive drugs, not elsewhere classified	0.657	0.343
T46.3 Coronary vasodilators, not elsewhere classified	0.657	0.343
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.657	0.343
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.657	0.343
S22.2 Fracture of sternum	0.657	0.343
Y89 Sequelae of other external causes	0.657	0.343
Y54.3 Benzothiadiazine derivatives	0.657	0.343
V48 Car occupant injured in noncollision transport accident	0.657	0.343
S41.1 Open wound of upper arm	0.657	0.343
S00.9 Superficial injury of head, part unspecified	0.656	0.344
Y41 Other systemic anti-infectives and antiparasitics	0.655	0.345
T36.0 Penicillins	0.655	0.345
S67 Crushing injury of wrist and hand	0.654	0.345
Y88 Sequelae of surgical and medical care as external cause	0.653	0.347
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.653	0.347
M88 Paget's disease of bone [osteitis deformans]	0.652	0.348
H65-H75 Diseases of middle ear and mastoid	0.649	0.351
S63.6 Sprain and strain of finger(s)	0.649	0.351
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.648	0.352
Y54.9 Mineral salts, not elsewhere classified	0.648	0.352
Y54.8 Agents affecting uric acid metabolism	0.648	0.352
Y54.7 Agents affecting calcification	0.648	0.352
Y54.6 Electrolytic, caloric and water-balance agents	0.648	0.352
Y54.4 Loop [high-ceiling] diuretics	0.648	0.352
Y54.2 Carbonic-anhydrase inhibitors	0.648	0.352
Y54.0 Mineralocorticoids	0.648	0.352
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.647	0.353
S48 Traumatic amputation of shoulder and upper arm	0.646	0.354
S45 Injury of blood vessels at shoulder and upper arm level	0.646	0.354
S44 Injury of nerves at shoulder and upper arm level	0.646	0.354
S47 Crushing injury of shoulder and upper arm	0.646	0.354
G96 Other disorders of central nervous system	0.646	0.354
S62.7 Multiple fractures of fingers	0.646	0.354
S62.4 Multiple fractures of metacarpal bones	0.646	0.354
S62.1 Fracture of other carpal bone(s)	0.646	0.354
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.645	0.355
Y49.2 Other and unspecified antidepressants	0.645	0.355
G00-G09 Inflammatory diseases of the central nervous system	0.644	0.356
Y42.9 Other and unspecified hormone antagonists	0.642	0.357
Y42.4 Oral contraceptives	0.642	0.357
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.642	0.357
Y42.2 Antithyroid drugs	0.642	0.357
Y42.1 Thyroid hormones and substitutes	0.642	0.357
Y42.0 Glucocorticoids and synthetic analogs	0.642	0.357
M67.2 Synovial hypertrophy, not elsewhere classified	0.641	0.359
Q80-Q89 Other congenital malformations	0.640	0.360
M45-M49 Spondylopathies	0.640	0.360
O42 Premature rupture of membranes	0.639	0.360
S66 Injury of muscle and tendon at wrist and hand level	0.639	0.361
S01.2 Open wound of nose	0.637	0.363
L51 Erythema multiforme	0.637	0.363
Q28 Other congenital malformations of circulatory system	0.635	0.365
G83 Other paralytic syndromes	0.635	0.365
M31.9 Necrotising vasculopathy, unspecified	0.634	0.365
M31.8 Other specified necrotising vasculopathies	0.634	0.365
M31.7 Microscopic polyangiitis	0.634	0.365
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.634	0.365
M31.4 Aortic arch syndrome [Takayasu]	0.634	0.365
M31.2 Lethal midline granuloma	0.634	0.365
M31.1 Thrombotic microangiopathy	0.634	0.365
M31.0 Hypersensitivity angiitis	0.634	0.365
F31 Bipolar affective disorder	0.634	0.366
S22.9 Fracture of bony thorax, part unspecified	0.633	0.367
S22.8 Fracture of other parts of bony thorax	0.633	0.367
S22.5 Flail chest	0.633	0.367
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.632	0.367
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.632	0.368
S00.5 Superficial injury of lip and oral cavity	0.631	0.369
G93 Other disorders of brain	0.630	0.370
L40.4 Guttate psoriasis	0.629	0.371
L40.3 Pustulosis palmaris et plantaris	0.629	0.371
L40.2 Acrodermatitis continua	0.629	0.371
L40.1 Generalised pustular psoriasis	0.629	0.371
M20.4 Other hammer toe(s) (acquired)	0.627	0.373
S62.3 Fracture of other metacarpal bone	0.627	0.373
Y52.4 Angiotensin-converting-enzyme inhibitors	0.627	0.373
M24.8 Other specific joint derangements, not elsewhere classified	0.627	0.373
W07.9 Unspecified place	0.627	0.373
Y00 Assault by blunt object	0.626	0.373
F23 Acute and transient psychotic disorders	0.626	0.373
G90 Disorders of autonomic nervous system	0.626	0.374
S19 Other and unspecified injuries of neck	0.626	0.374
G62 Other polyneuropathies	0.625	0.375
M10 Gout	0.625	0.375
S27.0 Traumatic pneumothorax	0.625	0.375
S69 Other and unspecified injuries of wrist and hand	0.624	0.376
M21.9 Acquired deformity of limb, unspecified	0.623	0.377
M21.8 Other specified acquired deformities of limbs	0.623	0.377
M21.7 Unequal limb length (acquired)	0.623	0.377
M21.4 Flat foot [pes planus] (acquired)	0.623	0.377
X59 Exposure to unspecified factor	0.623	0.377
S22.1 Multiple fractures of thoracic spine	0.622	0.378
F42 Obsessive-compulsive disorder	0.622	0.378
O46 Antepartum haemorrhage, not elsewhere classified	0.621	0.379
G80 Infantile cerebral palsy	0.621	0.379
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.621	0.379
W11.6 Industrial and construction area	0.621	0.379
T43.3 Phenothiazine antipsychotics and neuroleptics	0.621	0.379
M87 Osteonecrosis	0.620	0.380
Chapter XI Diseases of the digestive system	0.620	0.380
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.619	0.380
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.619	0.380
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.619	0.380
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.619	0.380
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.619	0.380
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.619	0.380
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.619	0.380
S62.0 Fracture of navicular [scaphoid] bone of hand	0.619	0.380
S80-S89 Injuries to the knee and lower leg	0.619	0.381
F99-F99 Unspecified mental disorder	0.618	0.381
T45.0 Antiallergic and antiemetic drugs	0.618	0.382
T50.8 Diagnostic agents	0.617	0.382
T50.7 Analeptics and opioid receptor antagonists	0.617	0.382
T50.6 Antidotes and chelating agents, not elsewhere classified	0.617	0.382
T50.5 Appetite depressants	0.617	0.382
T50.4 Drugs affecting uric acid metabolism	0.617	0.382
T50.3 Electrolytic, caloric and water-balance agents	0.617	0.382
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.617	0.382
T50.1 Loop [high-ceiling] diuretics	0.617	0.382
T50.0 Mineralocorticoids and their antagonists	0.617	0.382
F29 Unspecified nonorganic psychosis	0.617	0.382
T65 Toxic effect of other and unspecified substances	0.617	0.383
T62 Toxic effect of other noxious substances eaten as food	0.617	0.383
T61 Toxic effect of noxious substances eaten as seafood	0.617	0.383
T60 Toxic effect of pesticides	0.617	0.383
T59 Toxic effect of other gases, fumes and vapours	0.617	0.383
T57 Toxic effect of other inorganic substances	0.617	0.383
T54 Toxic effect of corrosive substances	0.617	0.383
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.617	0.383
T52 Toxic effect of organic solvents	0.617	0.383
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.617	0.383
T58 Toxic effect of carbon monoxide	0.617	0.383
T55 Toxic effect of soaps and detergents	0.617	0.383
M21.6 Other acquired deformities of ankle and foot	0.617	0.383
F60 Specific personality disorders	0.616	0.383
W13 Fall from, out of or through building or structure	0.616	0.384
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.615	0.384
Q38-Q45 Other congenital malformations of the digestive system	0.615	0.384
Q60 Renal agenesis and other reduction defects of kidney	0.615	0.385
S09.8 Other specified injuries of head	0.615	0.385
Y79 Orthopaedic devices associated with adverse incidents	0.614	0.386
T43.9 Psychotropic drug, unspecified	0.614	0.386
T43.8 Other psychotropic drugs, not elsewhere classified	0.614	0.386
T43.6 Psychostimulants with abuse potential	0.614	0.386

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations