TreeWAS – Variant ID: rs62246343

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D69 Purpura and other haemorrhagic conditions	0.349	0.651	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.349	0.651	0.000
D69.6 Thrombocytopenia, unspecified	0.343	0.657	0.000
D69.5 Secondary thrombocytopenia	0.328	0.672	0.000
D69.4 Other primary thrombocytopenia	0.274	0.726	0.000
D69.0 Allergic purpura	0.263	0.737	0.000
D69.9 Haemorrhagic condition, unspecified	0.253	0.747	0.000
D69.8 Other specified haemorrhagic conditions	0.250	0.750	0.000
D69.2 Other nonthrombocytopenic purpura	0.250	0.750	0.000
D69.1 Qualitative platelet defects	0.250	0.750	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.124	0.876	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.098	0.902	0.000
D66 Hereditary factor VIII deficiency	0.097	0.902	0.000
D67 Hereditary factor IX deficiency	0.089	0.910	0.000
K74 Fibrosis and cirrhosis of liver	0.050	0.950	0.000
K74.3 Primary biliary cirrhosis	0.049	0.951	0.000
K74.6 Other and unspecified cirrhosis of liver	0.046	0.954	0.000
K74.0 Hepatic fibrosis	0.043	0.957	0.000
K70-K77 Diseases of liver	0.043	0.957	0.000
K74.5 Biliary cirrhosis, unspecified	0.043	0.957	0.000
N05 Unspecified nephritic syndrome	0.040	0.960	0.000
N00-N08 Glomerular diseases	0.039	0.961	0.000
K72 Hepatic failure, not elsewhere classified	0.039	0.961	0.000
D68 Other coagulation defects	0.039	0.961	0.000
N04 Nephrotic syndrome	0.038	0.962	0.000
K70 Alcoholic liver disease	0.038	0.962	0.000
K72.9 Hepatic failure, unspecified	0.037	0.963	0.000
N05.2 Diffuse membranous glomerulonephritis	0.037	0.963	0.000
K76 Other diseases of liver	0.037	0.963	0.000
K74.4 Secondary biliary cirrhosis	0.036	0.964	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.036	0.964	0.000
K74.1 Hepatic sclerosis	0.036	0.964	0.000
N04.9 Unspecified	0.036	0.964	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.036	0.964	0.000
N05.9 Unspecified	0.036	0.964	0.000
K70.4 Alcoholic hepatic failure	0.036	0.964	0.000
K73 Chronic hepatitis, not elsewhere classified	0.034	0.966	0.000
K76.9 Liver disease, unspecified	0.034	0.966	0.000
N03 Chronic nephritic syndrome	0.033	0.967	0.000
N05.8 Other	0.032	0.968	0.000
K70.3 Alcoholic cirrhosis of liver	0.032	0.968	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.031	0.969	0.000
K77 Liver disorders in diseases classified elsewhere	0.031	0.969	0.000
K71 Toxic liver disease	0.031	0.969	0.000
N04.2 Diffuse membranous glomerulonephritis	0.031	0.969	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.031	0.969	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.031	0.969	0.000
D68.0 Von Willebrand's disease	0.030	0.970	0.000
K76.6 Portal hypertension	0.030	0.970	0.000
N04.1 Focal and segmental glomerular lesions	0.030	0.970	0.000
N02 Recurrent and persistent haematuria	0.030	0.970	0.000
K70.1 Alcoholic hepatitis	0.030	0.970	0.000
N03.9 Unspecified	0.029	0.971	0.000
K76.8 Other specified diseases of liver	0.029	0.971	0.000
K70.0 Alcoholic fatty liver	0.029	0.971	0.000
N05.6 Dense deposit disease	0.029	0.971	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.029	0.971	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.029	0.971	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.029	0.971	0.000
N05.0 Minor glomerular abnormality	0.029	0.971	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.028	0.971	0.000
N06 Isolated proteinuria with specified morphological lesion	0.028	0.971	0.000
N01 Rapidly progressive nephritic syndrome	0.028	0.971	0.000
N00 Acute nephritic syndrome	0.028	0.971	0.000
D68.5 Primary Thrombophilia	0.028	0.972	0.000
K72.1 Chronic hepatic failure	0.028	0.972	0.000
D68.4 Acquired coagulation factor deficiency	0.028	0.972	0.000
D68.1 Hereditary factor XI deficiency	0.028	0.972	0.000
K76.7 Hepatorenal syndrome	0.028	0.972	0.000
N04.8 Other	0.028	0.972	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.028	0.972	0.000
N04.6 Dense deposit disease	0.028	0.972	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.028	0.972	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.028	0.972	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.028	0.972	0.000
N04.0 Minor glomerular abnormality	0.028	0.972	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.027	0.973	0.000
K73.9 Chronic hepatitis, unspecified	0.027	0.973	0.000
K76.5 Hepatic veno-occlusive disease	0.027	0.973	0.000
K76.4 Peliosis hepatis	0.027	0.973	0.000
K76.3 Infarction of liver	0.027	0.973	0.000
K76.2 Central haemorrhagic necrosis of liver	0.027	0.973	0.000
K76.1 Chronic passive congestion of liver	0.027	0.973	0.000
N02.8 Other	0.026	0.973	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.026	0.974	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.026	0.974	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.026	0.974	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.026	0.974	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.026	0.974	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.026	0.974	0.000
D68.9 Coagulation defect, unspecified	0.026	0.974	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.025	0.975	0.000
D68.6 Other Thrombophilia	0.025	0.975	0.000
K72.0 Acute and subacute hepatic failure	0.025	0.975	0.000
N05.1 Focal and segmental glomerular lesions	0.025	0.975	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.025	0.975	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.025	0.975	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.025	0.975	0.000
N02.2 Diffuse membranous glomerulonephritis	0.024	0.975	0.000
N03.8 Other	0.024	0.976	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.024	0.976	0.000
N03.6 Dense deposit disease	0.024	0.976	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.024	0.976	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.024	0.976	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.024	0.976	0.000
N03.2 Diffuse membranous glomerulonephritis	0.024	0.976	0.000
N03.1 Focal and segmental glomerular lesions	0.024	0.976	0.000
N03.0 Minor glomerular abnormality	0.024	0.976	0.000
K71.9 Toxic liver disease, unspecified	0.022	0.977	0.000
K71.8 Toxic liver disease with other disorders of liver	0.022	0.977	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.022	0.977	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.022	0.977	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.022	0.977	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.022	0.977	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.022	0.977	0.000
K71.2 Toxic liver disease with acute hepatitis	0.022	0.977	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.022	0.977	0.000
K71.0 Toxic liver disease with cholestasis	0.022	0.977	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.022	0.977	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.022	0.977	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.022	0.978	0.000
N02.6 Dense deposit disease	0.022	0.978	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.022	0.978	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.022	0.978	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.022	0.978	0.000
N02.1 Focal and segmental glomerular lesions	0.022	0.978	0.000
N02.0 Minor glomerular abnormality	0.022	0.978	0.000
K75 Other inflammatory liver diseases	0.022	0.978	0.000
N00.9 Unspecified	0.020	0.979	0.000
N00.8 Other	0.020	0.979	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.020	0.979	0.000
N00.6 Dense deposit disease	0.020	0.979	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.020	0.979	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.020	0.979	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.020	0.979	0.000
N00.2 Diffuse membranous glomerulonephritis	0.020	0.979	0.000
N00.1 Focal and segmental glomerular lesions	0.020	0.979	0.000
N00.0 Minor glomerular abnormality	0.020	0.979	0.000
N01.9 Unspecified	0.020	0.979	0.000
N01.8 Other	0.020	0.979	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.020	0.979	0.000
N01.6 Dense deposit disease	0.020	0.979	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.020	0.979	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.020	0.979	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.020	0.979	0.000
N01.2 Diffuse membranous glomerulonephritis	0.020	0.979	0.000
N01.1 Focal and segmental glomerular lesions	0.020	0.979	0.000
N01.0 Minor glomerular abnormality	0.020	0.979	0.000
N06.9 Unspecified	0.020	0.979	0.000
N06.8 Other	0.020	0.979	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.020	0.979	0.000
N06.6 Dense deposit disease	0.020	0.979	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.020	0.979	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.020	0.979	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.020	0.979	0.000
N06.2 Diffuse membranous glomerulonephritis	0.020	0.979	0.000
N06.1 Focal and segmental glomerular lesions	0.020	0.979	0.000
N06.0 Minor glomerular abnormality	0.020	0.979	0.000
N07.9 Unspecified	0.020	0.979	0.000
N07.8 Other	0.020	0.979	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.020	0.979	0.000
N07.6 Dense deposit disease	0.020	0.979	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.020	0.979	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.020	0.979	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.020	0.979	0.000
N07.2 Diffuse membranous glomerulonephritis	0.020	0.979	0.000
N07.1 Focal and segmental glomerular lesions	0.020	0.979	0.000
N07.0 Minor glomerular abnormality	0.020	0.979	0.000
K75.4 Autoimmune hepatitis	0.017	0.983	0.000
K75.8 Other specified inflammatory liver diseases	0.017	0.983	0.000
D68.8 Other specified coagulation defects	0.016	0.984	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.016	0.984	0.000
K75.2 Nonspecific reactive hepatitis	0.016	0.984	0.000
K75.1 Phlebitis of portal vein	0.016	0.984	0.000
D68.2 Hereditary deficiency of other clotting factors	0.015	0.985	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.015	0.985	0.000
K70.9 Alcoholic liver disease, unspecified	0.014	0.986	0.000
F05.9 Delirium, unspecified	0.000	0.986	0.014
M20.2 Hallux rigidus	0.013	0.987	0.000
M20.3 Other deformity of hallux (acquired)	0.012	0.988	0.000
M20 Acquired deformities of fingers and toes	0.012	0.988	0.000
M20.1 Hallux valgus (acquired)	0.011	0.989	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.989	0.011
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.011	0.989	0.000
M20.5 Other deformities of toe(s) (acquired)	0.010	0.990	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.990	0.009
K75.9 Inflammatory liver disease, unspecified	0.009	0.991	0.000
M20.4 Other hammer toe(s) (acquired)	0.009	0.991	0.000
H40.2 Primary angle-closure glaucoma	0.009	0.991	0.000
H40.0 Glaucoma suspect	0.009	0.991	0.000
D55-D59 Haemolytic anaemias	0.008	0.992	0.000
K75.0 Abscess of liver	0.008	0.992	0.000
H40 Glaucoma	0.008	0.992	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.992	0.008
F01.9 Vascular dementia, unspecified	0.000	0.992	0.007
R90.0 Intracranial space-occupying lesion	0.000	0.993	0.007
F01 Vascular dementia	0.000	0.993	0.007
F05.8 Other delirium	0.000	0.993	0.007
N02.9 Unspecified	0.007	0.993	0.000
M20.0 Deformity of finger(s)	0.007	0.993	0.000
H40.8 Other glaucoma	0.007	0.993	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.007	0.993	0.000
D80-D89 Certain disorders involving the immune mechanism	0.007	0.993	0.000
D60-D64 Aplastic and other anaemias	0.007	0.993	0.000
D57 Sickle-cell disorders	0.007	0.993	0.000
F05.1 Delirium superimposed on dementia	0.000	0.993	0.007
F03 Unspecified dementia	0.000	0.993	0.007
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.007	0.993	0.000
H40.4 Glaucoma secondary to eye inflammation	0.007	0.993	0.000
D58 Other hereditary haemolytic anaemias	0.006	0.993	0.000
K50.9 Crohn's disease, unspecified	0.000	0.994	0.006
D55 Anaemia due to enzyme disorders	0.006	0.994	0.000
D62 Acute posthaemorrhagic anaemia	0.006	0.994	0.000
D56 Thalassaemia	0.006	0.994	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.994	0.006
D57.1 Sickle-cell anaemia without crisis	0.006	0.994	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.994	0.006
D89.9 Disorder involving the immune mechanism, unspecified	0.006	0.994	0.000
M31.3 Wegener's granulomatosis	0.006	0.994	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.994	0.006
D59 Acquired haemolytic anaemia	0.006	0.994	0.000
H40.6 Glaucoma secondary to drugs	0.006	0.994	0.000
F02 Dementia in other diseases classified elsewhere	0.000	0.994	0.006
D89.2 Hypergammaglobulinaemia, unspecified	0.006	0.994	0.000
F09 Unspecified organic or symptomatic mental disorder	0.000	0.994	0.006
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.994	0.006
H40.3 Glaucoma secondary to eye trauma	0.006	0.994	0.000
F00 Dementia in Alzheimer's disease	0.000	0.994	0.006
D84 Other immunodeficiencies	0.006	0.994	0.000
F01.8 Other vascular dementia	0.000	0.994	0.005
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.994	0.005
F01.2 Subcortical vascular dementia	0.000	0.994	0.005
F01.1 Multi-infarct dementia	0.000	0.994	0.005
F01.0 Vascular dementia of acute onset	0.000	0.994	0.005
F05.0 Delirium not superimposed on dementia, so described	0.000	0.994	0.005
M20.6 Acquired deformity of toe(s), unspecified	0.005	0.994	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.005	0.994	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.994	0.005
K50.0 Crohn's disease of small intestine	0.000	0.995	0.005
D82 Immunodeficiency associated with other major defects	0.005	0.995	0.000
D81 Combined immunodeficiencies	0.005	0.995	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.000	0.995	0.005
M21.1 Varus deformity, not elsewhere classified	0.005	0.995	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.005	0.995	0.000
D57.8 Other sickle-cell disorders	0.005	0.995	0.000
D57.3 Sickle-cell trait	0.005	0.995	0.000
D57.2 Double heterozygous sickling disorders	0.005	0.995	0.000
D57.0 Sickle-cell anaemia with crisis	0.005	0.995	0.000
D83 Common variable immunodeficiency	0.005	0.995	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.005	0.995	0.000
H18 Other disorders of cornea	0.005	0.995	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
D89.3 Immune reconstitution syndrome	0.005	0.995	0.000
D89.1 Cryoglobulinaemia	0.005	0.995	0.000
M95.0 Acquired deformity of nose	0.005	0.995	0.000
F07.2 Postconcussional syndrome	0.000	0.995	0.005
D58.8 Other specified hereditary haemolytic anaemias	0.005	0.995	0.000
D58.2 Other haemoglobinopathies	0.005	0.995	0.000
D58.1 Hereditary elliptocytosis	0.005	0.995	0.000
H18.9 Disorder of cornea, unspecified	0.005	0.995	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.995	0.005
D63 Anaemia in chronic diseases classified elsewhere	0.005	0.995	0.000
H18.8 Other specified disorders of cornea	0.005	0.995	0.000
H18.5 Hereditary corneal dystrophies	0.005	0.995	0.000
M31 Other necrotising vasculopathies	0.005	0.995	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.005	0.995	0.000
D55.8 Other anaemias due to enzyme disorders	0.005	0.995	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.005	0.995	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.005	0.995	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.005	0.995	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.005	0.995	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.995	0.005
H18.6 Keratoconus	0.005	0.995	0.000
D56.9 Thalassaemia, unspecified	0.004	0.995	0.000
D56.8 Other thalassaemias	0.004	0.995	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.004	0.995	0.000
D56.2 Delta-beta thalassaemia	0.004	0.995	0.000
D56.0 Alpha thalassaemia	0.004	0.995	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.995	0.004
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.995	0.004
F07.1 Postencephalitic syndrome	0.000	0.995	0.004
F07.0 Organic personality disorder	0.000	0.995	0.004
D56.3 Thalassaemia trait	0.004	0.995	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.995	0.005
D70-D77 Other diseases of blood and blood-forming organs	0.005	0.995	0.000
D61 Other aplastic anaemias	0.005	0.995	0.000
D80 Immunodeficiency with predominantly antibody defects	0.004	0.995	0.000
D58.0 Hereditary spherocytosis	0.004	0.995	0.000
D84.9 Immunodeficiency, unspecified	0.004	0.995	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.995	0.005
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.995	0.004
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.995	0.004
D51.2 Transcobalamin II deficiency	0.000	0.995	0.004
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.995	0.004
D59.9 Acquired haemolytic anaemia, unspecified	0.004	0.995	0.000
D56.1 Beta thalassaemia	0.004	0.995	0.000
H18.1 Bullous keratopathy	0.004	0.995	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.996	0.004
D59.8 Other acquired haemolytic anaemias	0.004	0.996	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.004	0.996	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.004	0.996	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.004	0.996	0.000
D59.3 Haemolytic-uraemic syndrome	0.004	0.996	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.004	0.996	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.004	0.996	0.000
H40.9 Glaucoma, unspecified	0.004	0.996	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.996	0.004
F02.2 Dementia in Huntington's disease	0.000	0.996	0.004
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.996	0.004
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.996	0.004
D84.8 Other specified immunodeficiencies	0.004	0.996	0.000
D84.1 Defects in the complement system	0.004	0.996	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.004	0.996	0.000
F02.0 Dementia in Pick's disease	0.000	0.996	0.004
F02.3 Dementia in Parkinson's disease	0.000	0.996	0.004
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.996	0.004
M21 Other acquired deformities of limbs	0.004	0.996	0.000
D81.9 Combined immunodeficiency, unspecified	0.004	0.996	0.000
D81.8 Other combined immunodeficiencies	0.004	0.996	0.000
D81.7 Major histocompatibility complex class II deficiency	0.004	0.996	0.000
D81.6 Major histocompatibility complex class I deficiency	0.004	0.996	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.004	0.996	0.000
D81.4 Nezelof's syndrome	0.004	0.996	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.004	0.996	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.004	0.996	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.004	0.996	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.004	0.996	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.004	0.996	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.004	0.996	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.004	0.996	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.004	0.996	0.000
D82.2 Immunodeficiency with short-limbed stature	0.004	0.996	0.000
D82.1 Di George's syndrome	0.004	0.996	0.000
D82.0 Wiskott-Aldrich syndrome	0.004	0.996	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.004	0.996	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.004	0.996	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.004	0.996	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.004	0.996	0.000
H40-H42 Glaucoma	0.004	0.996	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.004	0.996	0.000
D60.8 Other acquired pure red cell aplasias	0.004	0.996	0.000
D60.1 Transient acquired pure red cell aplasia	0.004	0.996	0.000
D60.0 Chronic acquired pure red cell aplasia	0.004	0.996	0.000
M21.4 Flat foot [pes planus] (acquired)	0.004	0.996	0.000
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
D83.8 Other common variable immunodeficiencies	0.004	0.996	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.004	0.996	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.004	0.996	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.004	0.996	0.000
K50.8 Other Crohn's disease	0.000	0.996	0.004
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.004	0.996	0.000
H18.7 Other corneal deformities	0.004	0.996	0.000
H18.3 Changes in corneal membranes	0.004	0.996	0.000
D72 Other disorders of white blood cells	0.004	0.996	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.004	0.996	0.000
M31.6 Other giant cell arteritis	0.004	0.996	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.004	0.996	0.000
D83.9 Common variable immunodeficiency, unspecified	0.004	0.996	0.000
O26.8 Other specified pregnancy-related conditions	0.000	0.996	0.004
H40.5 Glaucoma secondary to other eye disorders	0.004	0.996	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.004	0.996	0.000
D59.1 Other autoimmune haemolytic anaemias	0.004	0.996	0.000
D72.8 Other specified disorders of white blood cells	0.004	0.996	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.996	0.004
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.004	0.996	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.996	0.004
D61.1 Drug-induced aplastic anaemia	0.004	0.996	0.000
D73.5 Infarction of spleen	0.004	0.996	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.004	0.996	0.000
M31.9 Necrotising vasculopathy, unspecified	0.004	0.996	0.000
M31.8 Other specified necrotising vasculopathies	0.004	0.996	0.000
M31.7 Microscopic polyangiitis	0.004	0.996	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.004	0.996	0.000
M31.2 Lethal midline granuloma	0.004	0.996	0.000
M31.1 Thrombotic microangiopathy	0.004	0.996	0.000
M31.0 Hypersensitivity angiitis	0.004	0.996	0.000
D73 Diseases of spleen	0.004	0.996	0.000
H15 Disorders of sclera	0.004	0.996	0.000
K36 Other appendicitis	0.004	0.996	0.000
D61.0 Constitutional aplastic anaemia	0.004	0.996	0.000
M20-M25 Other joint disorders	0.004	0.996	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.996	0.004
H15.1 Episcleritis	0.004	0.996	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.004	0.996	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.996	0.004
D64 Other anaemias	0.004	0.996	0.000
D76.3 Other histiocytosis syndromes	0.004	0.996	0.000
D61.8 Other specified aplastic anaemias	0.003	0.996	0.000
D61.3 Idiopathic aplastic anaemia	0.003	0.996	0.000
D61.2 Aplastic anaemia due to other external agents	0.003	0.996	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.003	0.996	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.003	0.996	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.003	0.996	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.003	0.996	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.996	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.003	0.996	0.000
D74 Methaemoglobinaemia	0.003	0.996	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.003	0.996	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.003	0.996	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.996	0.003
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.996	0.003
F06.5 Organic dissociative disorder	0.000	0.996	0.003
F06.4 Organic anxiety disorder	0.000	0.996	0.003
F06.3 Organic mood [affective] disorders	0.000	0.996	0.003
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.996	0.003
F06.1 Organic catatonic disorder	0.000	0.996	0.003
F06.0 Organic hallucinosis	0.000	0.996	0.003
D63.0 Anaemia in neoplastic disease	0.003	0.996	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.003	0.996	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.003	0.997	0.000
O26.9 Pregnancy-related condition, unspecified	0.000	0.997	0.003
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
M32 Systemic lupus erythematosus	0.003	0.997	0.000
M21.8 Other specified acquired deformities of limbs	0.003	0.997	0.000
M21.7 Unequal limb length (acquired)	0.003	0.997	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.003	0.997	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.003	0.997	0.000
M21.9 Acquired deformity of limb, unspecified	0.003	0.997	0.000
H17 Corneal scars and opacities	0.003	0.997	0.000
M24.28 Disorder of ligament (Other)	0.003	0.997	0.000
M24 Other specific joint derangements	0.003	0.997	0.000
H42 Glaucoma in diseases classified elsewhere	0.003	0.997	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.003	0.997	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.003	0.997	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.003	0.997	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.003	0.997	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.003	0.997	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.003	0.997	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.003	0.997	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.003	0.997	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.003	0.997	0.000
D73.8 Other diseases of spleen	0.003	0.997	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.003	0.997	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.003	0.997	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.003	0.997	0.000
H21 Other disorders of iris and ciliary body	0.003	0.997	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.997	0.003
H18.2 Other corneal oedema	0.003	0.997	0.000
D72.9 Disorder of white blood cells, unspecified	0.003	0.997	0.000
D72.0 Genetic anomalies of leukocytes	0.003	0.997	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.003	0.997	0.000
F06.7 Mild cognitive disorder	0.000	0.997	0.003
M32.1 Systemic lupus erythematosus with organ or system involvement	0.003	0.997	0.000
M24.2 Disorder of ligament	0.003	0.997	0.000
H18.4 Corneal degeneration	0.003	0.997	0.000
M21.2 Flexion deformity	0.003	0.997	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.003	0.997	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.997	0.003
H15.0 Scleritis	0.003	0.997	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.003	0.997	0.000
D73.9 Disease of spleen, unspecified	0.003	0.997	0.000
D73.4 Cyst of spleen	0.003	0.997	0.000
D73.3 Abscess of spleen	0.003	0.997	0.000
D73.2 Chronic congestive splenomegaly	0.003	0.997	0.000
H15.9 Disorder of sclera, unspecified	0.003	0.997	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.003	0.997	0.000
M30 Polyarteritis nodosa and related conditions	0.003	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.003	0.997	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.997	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H16 Keratitis	0.003	0.997	0.000
D50-D53 Nutritional anaemias	0.002	0.997	0.001
D64.4 Congenital dyserythropoietic anaemia	0.003	0.997	0.000
D64.3 Other sideroblastic anaemias	0.003	0.997	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.003	0.997	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.003	0.997	0.000
D64.0 Hereditary sideroblastic anaemia	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
H15.8 Other disorders of sclera	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.000	0.997	0.003
C71.3 Parietal lobe	0.000	0.997	0.003
D64.8 Other specified anaemias	0.003	0.997	0.000
I86.8 Varicose veins of other specified sites	0.003	0.997	0.000
M23.8 Other internal derangements of knee	0.000	0.997	0.003
Q61 Cystic kidney disease	0.000	0.997	0.003
M24.11 Other articular cartilage disorders (Shoulder region)	0.003	0.997	0.000
D74.9 Methaemoglobinaemia, unspecified	0.003	0.997	0.000
D74.8 Other methaemoglobinaemias	0.003	0.997	0.000
D74.0 Congenital methaemoglobinaemia	0.003	0.997	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.997	0.003
M21.3 Wrist or foot drop (acquired)	0.003	0.997	0.000
D73.1 Hypersplenism	0.003	0.997	0.000
M24.1 Other articular cartilage disorders	0.003	0.997	0.000
H17.8 Other corneal scars and opacities	0.003	0.997	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.003	0.997	0.000
M21.0 Valgus deformity, not elsewhere classified	0.003	0.997	0.000
M25.84 Other specified joint disorders (Hand)	0.003	0.997	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.003	0.997	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.003	0.997	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations