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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62262521
log Bayes Factor = 5.68817
Chromosome 3   position 49,173,197  (GRCh37) Explore rs62262521 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.997 0.003 0.000
M45-M49 Spondylopathies
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.992 0.008 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.990 0.010 0.000
H90-H95 Other disorders of ear
0.986 0.014 0.000
M05-M14 Inflammatory polyarthropathies
0.984 0.016 0.000
M47 Spondylosis
0.984 0.016 0.000
M80-M85 Disorders of bone density and structure
0.981 0.019 0.000
Chapter V Mental and behavioural disorders
0.975 0.025 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.973 0.027 0.000
H55-H59 Other disorders of eye and adnexa
0.970 0.030 0.000
M13 Other arthritis
0.966 0.034 0.000
M47.2 Other spondylosis with radiculopathy
0.965 0.035 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.962 0.038 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.961 0.039 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.959 0.041 0.000
K86 Other diseases of pancreas
0.959 0.041 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.956 0.044 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.954 0.046 0.000
K80 Cholelithiasis
0.953 0.047 0.000
H53-H54 Visual disturbances and blindness
0.951 0.049 0.000
M13.9 Arthritis, unspecified
0.949 0.051 0.000
H65-H75 Diseases of middle ear and mastoid
0.949 0.051 0.000
S60-S69 Injuries to the wrist and hand
0.948 0.052 0.000
M06 Other rheumatoid arthritis
0.944 0.056 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.940 0.060 0.000
Y54.3 Benzothiadiazine derivatives
0.937 0.063 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.936 0.064 0.000
M47.8 Other spondylosis
0.936 0.064 0.000
Chapter XI Diseases of the digestive system
0.935 0.065 0.000
H53 Visual disturbances
0.930 0.070 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.930 0.070 0.000
H55 Nystagmus and other irregular eye movements
0.929 0.071 0.000
M81 Osteoporosis without pathological fracture
0.926 0.074 0.000
H90 Conductive and sensorineural hearing loss
0.923 0.077 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.920 0.080 0.000
K86.2 Cyst of pancreas
0.918 0.082 0.000
F10.2 Dependence syndrome
0.917 0.083 0.000
S10-S19 Injuries to the neck
0.910 0.090 0.000
S61 Open wound of wrist and hand
0.903 0.097 0.000
H52 Disorders of refraction and accommodation
0.901 0.099 0.000
M20-M25 Other joint disorders
0.899 0.101 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.897 0.103 0.000
K83 Other diseases of biliary tract
0.894 0.106 0.000
M06.9 Rheumatoid arthritis, unspecified
0.892 0.108 0.000
M45 Ankylosing spondylitis
0.890 0.110 0.000
M81.9 Osteoporosis, unspecified
0.890 0.110 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.888 0.112 0.000
M13.94 Arthritis, unspecified (Hand)
0.886 0.114 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.886 0.114 0.000
M47.82 Other spondylosis (Cervical region)
0.884 0.116 0.000
H52.1 Myopia
0.884 0.116 0.000
M84 Disorders of continuity of bone
0.884 0.116 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.878 0.122 0.000
H53.0 Amblyopia ex anopsia
0.876 0.124 0.000
K86.1 Other chronic pancreatitis
0.876 0.124 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.873 0.127 0.000
F10.3 Withdrawal state
0.869 0.131 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.869 0.131 0.000
S40-S49 Injuries to the shoulder and upper arm
0.864 0.136 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.864 0.136 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.862 0.137 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.861 0.139 0.000
M25 Other joint disorders, not elsewhere classified
0.860 0.140 0.000
H57 Other disorders of eye and adnexa
0.858 0.142 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.858 0.142 0.000
M48 Other spondylopathies
0.857 0.143 0.000
H90.3 Sensorineural hearing loss, bilateral
0.857 0.143 0.000
M86-M90 Other osteopathies
0.856 0.144 0.000
H71 Cholesteatoma of middle ear
0.855 0.145 0.000
H50 Other strabismus
0.851 0.149 0.000
Chapter XXII Codes for special purposes
0.850 0.150 0.000
F30-F39 Mood [affective] disorders
0.849 0.151 0.000
K83.1 Obstruction of bile duct
0.847 0.153 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.835 0.165 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.834 0.166 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.832 0.168 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.831 0.169 0.000
H92 Otalgia and effusion of ear
0.828 0.172 0.000
Y54.8 Agents affecting uric acid metabolism
0.826 0.174 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.821 0.179 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.820 0.180 0.000
H72 Perforation of tympanic membrane
0.819 0.181 0.000
M60-M63 Disorders of muscles
0.817 0.183 0.000
F10.0 Acute intoxication
0.816 0.184 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.815 0.185 0.000
H95.1 Other disorders following mastoidectomy
0.814 0.185 0.000
S61.8 Open wound of other parts of wrist and hand
0.814 0.186 0.000
S20-S29 Injuries to the thorax
0.813 0.187 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.813 0.187 0.000
H53.2 Diplopia
0.813 0.187 0.000
S61.0 Open wound of finger(s) without damage to nail
0.812 0.188 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.812 0.188 0.000
M84.0 Malunion of fracture
0.812 0.188 0.000
H53.8 Other visual disturbances
0.811 0.189 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.809 0.191 0.000
S40 Superficial injury of shoulder and upper arm
0.808 0.192 0.000
M31 Other necrotising vasculopathies
0.806 0.194 0.000
S00-S09 Injuries to the head
0.805 0.195 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.801 0.199 0.000
K86.9 Disease of pancreas, unspecified
0.799 0.201 0.000
H90.0 Conductive hearing loss, bilateral
0.799 0.201 0.000
H74 Other disorders of middle ear and mastoid
0.798 0.202 0.000
H93 Other disorders of ear, not elsewhere classified
0.798 0.202 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.797 0.203 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.795 0.205 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.794 0.206 0.000
H60-H62 Diseases of external ear
0.794 0.206 0.000
M80 Osteoporosis with pathological fracture
0.793 0.207 0.000
M47.89 Other spondylosis (Site unspecified)
0.793 0.207 0.000
K86.3 Pseudocyst of pancreas
0.791 0.209 0.000
M25.5 Pain in joint
0.790 0.210 0.000
Y57 Other and unspecified drugs and medicaments
0.790 0.210 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.790 0.210 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.790 0.210 0.000
M06.4 Inflammatory polyarthropathy
0.789 0.211 0.000
V40-V49 Car occupant injured in transport accident
0.789 0.211 0.000
T00-T07 Injuries involving multiple body regions
0.785 0.215 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.784 0.216 0.000
F10.1 Harmful use
0.783 0.217 0.000
K50-K52 Noninfective enteritis and colitis
0.781 0.219 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.779 0.221 0.000
S61.1 Open wound of finger(s) with damage to nail
0.779 0.221 0.000
S10 Superficial injury of neck
0.778 0.222 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.777 0.223 0.000
S32 Fracture of lumbar spine and pelvis
0.776 0.224 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.768 0.232 0.000
V20-V29 Motorcycle rider injured in transport accident
0.768 0.232 0.000
T51 Toxic effect of alcohol
0.768 0.232 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.768 0.232 0.000
K86.8 Other specified diseases of pancreas
0.766 0.234 0.000
S64 Injury of nerves at wrist and hand level
0.765 0.235 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.765 0.235 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.763 0.237 0.000
M13.98 Arthritis, unspecified (Other)
0.759 0.241 0.000
M48.0 Spinal stenosis
0.755 0.245 0.000
X60-X84 Intentional self-harm
0.755 0.245 0.000
K52 Other non-infective gastro-enteritis and colitis
0.753 0.247 0.000
M13.0 Polyarthritis, unspecified
0.753 0.247 0.000
Y42.5 Other oestrogens and progestogens
0.752 0.248 0.000
Y44 Agents primarily affecting blood constituents
0.752 0.248 0.000
M84.03 Malunion of fracture (Forearm)
0.751 0.249 0.000
W00-W19 Falls
0.750 0.250 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.749 0.251 0.000
Y48 Anaesthetics and therapeutic gases
0.748 0.252 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.748 0.252 0.000
H10-H13 Disorders of conjunctiva
0.748 0.252 0.000
M06.3 Rheumatoid nodule
0.747 0.253 0.000
H53.1 Subjective visual disturbances
0.745 0.255 0.000
W20-W49 Exposure to inanimate mechanical forces
0.745 0.255 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.745 0.255 0.000
F31 Bipolar affective disorder
0.744 0.256 0.000
H72.0 Central perforation of tympanic membrane
0.743 0.257 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.742 0.258 0.000
H70 Mastoiditis and related conditions
0.741 0.259 0.000
T91 Sequelae of injuries of neck and trunk
0.741 0.259 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.741 0.259 0.000
Y54.5 Other diuretics
0.740 0.260 0.000
V80-V89 Other land transport accidents
0.739 0.260 0.000
M00-M03 Infectious arthropathies
0.739 0.261 0.000
H43-H45 Disorders of vitreous body and globe
0.739 0.261 0.000
H50.1 Divergent concomitant strabismus
0.739 0.261 0.000
H60 Otitis externa
0.737 0.263 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.737 0.263 0.000
M25.0 Haemarthrosis
0.737 0.263 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.736 0.264 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.736 0.264 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.733 0.267 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.733 0.267 0.000
M24 Other specific joint derangements
0.731 0.269 0.000
W50-W64 Exposure to animate mechanical forces
0.729 0.270 0.000
S00 Superficial injury of head
0.729 0.271 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.728 0.271 0.000
H66 Suppurative and unspecified otitis media
0.727 0.273 0.000
S68 Traumatic amputation of wrist and hand
0.726 0.274 0.000
Y00-Y09 Assault
0.723 0.276 0.000
S30.2 Contusion of external genital organs
0.723 0.277 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.722 0.278 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.721 0.279 0.000
H91 Other hearing loss
0.721 0.279 0.000
S20 Superficial injury of thorax
0.718 0.282 0.000
X10-X19 Contact with heat and hot substances
0.718 0.282 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
Y40 Systemic antibiotics
0.716 0.284 0.000
M47.1 Other spondylosis with myelopathy
0.715 0.285 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.715 0.285 0.000
M84.4 Pathological fracture, not elsewhere classified
0.714 0.286 0.000
M49 Spondylopathies in diseases classified elsewhere
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.713 0.287 0.000
M82 Osteoporosis in diseases classified elsewhere
0.711 0.288 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.711 0.289 0.000
S30.0 Contusion of lower back and pelvis
0.711 0.289 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.711 0.289 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.710 0.290 0.000
Y59 Other and unspecified vaccines and biological substances
0.709 0.290 0.000
Y58 Bacterial vaccines
0.709 0.290 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.709 0.290 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.709 0.290 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.709 0.290 0.000
H92.1 Otorrhoea
0.708 0.292 0.000
F11 Mental and behavioural disorders due to use of opioids
0.708 0.292 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.707 0.293 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.707 0.293 0.000
T36 Poisoning by systemic antibiotics
0.707 0.293 0.000
S40.0 Contusion of shoulder and upper arm
0.707 0.293 0.000
M12 Other specific arthropathies
0.706 0.294 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.706 0.294 0.000
M08 Juvenile arthritis
0.706 0.294 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.706 0.294 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.294 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.705 0.295 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.705 0.295 0.000
H57.8 Other specified disorders of eye and adnexa
0.704 0.296 0.000
M83 Adult osteomalacia
0.703 0.297 0.000
M46 Other inflammatory spondylopathies
0.703 0.297 0.000
M89 Other disorders of bone
0.702 0.298 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.702 0.298 0.000
H50.4 Other and unspecified heterotropia
0.701 0.299 0.000
S06 Intracranial injury
0.701 0.299 0.000
M90 Osteopathies in diseases classified elsewhere
0.700 0.300 0.000
M25.8 Other specified joint disorders
0.699 0.301 0.000
S32.5 Fracture of pubis
0.699 0.301 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.699 0.301 0.000
F70-F79 Mental retardation
0.699 0.301 0.000
H90.5 Sensorineural hearing loss, unspecified
0.699 0.301 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.698 0.302 0.000
Y54.9 Mineral salts, not elsewhere classified
0.698 0.302 0.000
Y54.7 Agents affecting calcification
0.698 0.302 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.698 0.302 0.000
Y54.4 Loop [high-ceiling] diuretics
0.698 0.302 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.698 0.302 0.000
Y54.0 Mineralocorticoids
0.698 0.302 0.000
M91-M94 Chondropathies
0.697 0.303 0.000
F99-F99 Unspecified mental disorder
0.695 0.305 0.000
K65-K67 Diseases of peritoneum
0.695 0.305 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.694 0.306 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.694 0.306 0.000
M65-M68 Disorders of synovium and tendon
0.693 0.307 0.000
M13.8 Other specified arthritis
0.692 0.307 0.000
M13.1 Monoarthritis, not elsewhere classified
0.692 0.307 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.692 0.308 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.692 0.308 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.692 0.308 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.692 0.308 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.692 0.308 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.692 0.308 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.692 0.308 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.691 0.308 0.000
F10.4 Withdrawal state with delirium
0.691 0.309 0.000
X50-X57 Overexertion, travel and privation
0.691 0.309 0.000
F30 Manic episode
0.690 0.309 0.000
S36 Injury of intra-abdominal organs
0.690 0.310 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.689 0.311 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.689 0.311 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.689 0.311 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.689 0.311 0.000
M30 Polyarteritis nodosa and related conditions
0.689 0.311 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.689 0.311 0.000
M48.09 Spinal stenosis (Site unspecified)
0.688 0.312 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.688 0.312 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.688 0.312 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.688 0.312 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.688 0.312 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.688 0.312 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.688 0.312 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.688 0.312 0.000
H52.2 Astigmatism
0.687 0.313 0.000
S65 Injury of blood vessels at wrist and hand level
0.687 0.313 0.000
S67 Crushing injury of wrist and hand
0.687 0.313 0.000
M62 Other disorders of muscle
0.687 0.313 0.000
H51 Other disorders of binocular movement
0.685 0.315 0.000
H17 Corneal scars and opacities
0.684 0.316 0.000
F10.9 Unspecified mental and behavioural disorder
0.684 0.316 0.000
F10.8 Other mental and behavioural disorders
0.684 0.316 0.000
F10.7 Residual and late-onset psychotic disorder
0.684 0.316 0.000
F10.6 Amnesic syndrome
0.684 0.316 0.000
F10.5 Psychotic disorder
0.684 0.316 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.684 0.316 0.000
K80.3 Calculus of bile duct with cholangitis
0.683 0.316 0.000
T65 Toxic effect of other and unspecified substances
0.683 0.317 0.000
S10.9 Superficial injury of neck, part unspecified
0.683 0.317 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.682 0.318 0.000
M85 Other disorders of bone density and structure
0.680 0.319 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.680 0.320 0.000
H68 Eustachian salpingitis and obstruction
0.680 0.320 0.000
H67 Otitis media in diseases classified elsewhere
0.680 0.320 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.679 0.321 0.000
M06.8 Other specified rheumatoid arthritis
0.677 0.323 0.000
M06.2 Rheumatoid bursitis
0.677 0.323 0.000
M06.1 Adult-onset Still's disease
0.677 0.323 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.676 0.324 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.676 0.324 0.000
S41 Open wound of shoulder and upper arm
0.675 0.325 0.000
H15 Disorders of sclera
0.675 0.325 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.674 0.325 0.000
K52.3 Indeterminate colitis
0.674 0.326 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.674 0.326 0.000
S14 Injury of nerves and spinal cord at neck level
0.673 0.326 0.000
H21 Other disorders of iris and ciliary body
0.673 0.327 0.000
M25.54 Pain in joint (Hand)
0.673 0.327 0.000
S37 Injury of urinary and pelvic organs
0.673 0.327 0.000
S11 Open wound of neck
0.672 0.328 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.671 0.329 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.671 0.329 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.671 0.329 0.000
M47.84 Other spondylosis (Thoracic region)
0.671 0.329 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.671 0.329 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.671 0.329 0.000
F33 Recurrent depressive disorder
0.671 0.329 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.669 0.331 0.000
V10-V19 Pedal cyclist injured in transport accident
0.669 0.331 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.668 0.331 0.000
K52.1 Toxic gastro-enteritis and colitis
0.668 0.332 0.000
H53.6 Night blindness
0.667 0.333 0.000
H53.5 Colour vision deficiencies
0.667 0.333 0.000
H53.3 Other disorders of binocular vision
0.667 0.333 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.667 0.333 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.667 0.333 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.667 0.333 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.667 0.333 0.000
S31 Open wound of abdomen, lower back and pelvis
0.667 0.333 0.000
M31.3 Wegener's granulomatosis
0.667 0.333 0.000
T58 Toxic effect of carbon monoxide
0.666 0.334 0.000
H50.2 Vertical strabismus
0.666 0.334 0.000
M25.59 Pain in joint (Site unspecified)
0.666 0.334 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.664 0.335 0.000
Y95 Nosocomial condition
0.664 0.336 0.000
S90-S99 Injuries to the ankle and foot
0.664 0.336 0.000
M81.8 Other osteoporosis
0.664 0.336 0.000
M81.6 Localised osteoporosis [Lequesne]
0.664 0.336 0.000
M81.5 Idiopathic osteoporosis
0.664 0.336 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.664 0.336 0.000
M81.1 Postoophorectomy osteoporosis
0.664 0.336 0.000
M81.0 Postmenopausal osteoporosis
0.664 0.336 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.662 0.338 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.662 0.338 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.662 0.338 0.000
H93.1 Tinnitus
0.660 0.339 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.660 0.340 0.000
M33 Dermatopolymyositis
0.660 0.340 0.000
S69 Other and unspecified injuries of wrist and hand
0.660 0.340 0.000
H72.8 Other perforations of tympanic membrane
0.659 0.341 0.000
M22 Disorders of patella
0.659 0.341 0.000
S00.8 Superficial injury of other parts of head
0.658 0.342 0.000
H69 Other disorders of Eustachian tube
0.657 0.343 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.656 0.344 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.656 0.344 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.655 0.345 0.000
T42.4 Benzodiazepines
0.654 0.346 0.000
X45 Accidental poisoning by and exposure to alcohol
0.654 0.346 0.000
M31.6 Other giant cell arteritis
0.654 0.346 0.000
M81.2 Osteoporosis of disuse
0.654 0.346 0.000
T51.0 Ethanol
0.654 0.346 0.000
K85 Acute pancreatitis
0.653 0.346 0.000
M86 Osteomyelitis
0.653 0.347 0.000
M48.06 Spinal stenosis (Lumbar region)
0.653 0.347 0.000
S17 Crushing injury of neck
0.652 0.348 0.000
S15 Injury of blood vessels at neck level
0.652 0.348 0.000
S18 Traumatic amputation at neck level
0.652 0.348 0.000
S16 Injury of muscle and tendon at neck level
0.652 0.348 0.000
M11 Other crystal arthropathies
0.652 0.348 0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck
0.651 0.349 0.000
M31.9 Necrotising vasculopathy, unspecified
0.651 0.349 0.000
M25.06 Haemarthrosis (Lower leg)
0.649 0.351 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.649 0.351 0.000
K80.8 Other cholelithiasis
0.648 0.352 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.648 0.352 0.000
H60.9 Otitis externa, unspecified
0.648 0.352 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.648 0.352 0.000
M81.4 Drug-induced osteoporosis
0.648 0.352 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.648 0.352 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.647 0.353 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.646 0.354 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.646 0.354 0.000
H52.7 Disorder of refraction, unspecified
0.646 0.354 0.000
H52.6 Other disorders of refraction
0.646 0.354 0.000
H52.5 Disorders of accommodation
0.646 0.354 0.000
H52.4 Presbyopia
0.646 0.354 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.645 0.355 0.000
M32 Systemic lupus erythematosus
0.645 0.355 0.000
S32.50 Fracture of pubis (closed)
0.644 0.356 0.000
K83.0 Cholangitis
0.644 0.356 0.000
Y42.9 Other and unspecified hormone antagonists
0.643 0.357 0.000
Y42.4 Oral contraceptives
0.643 0.357 0.000
Y42.2 Antithyroid drugs
0.643 0.357 0.000
Y42.1 Thyroid hormones and substitutes
0.643 0.357 0.000
Y40.8 Other systemic antibiotics
0.642 0.358 0.000
S12 Fracture of neck
0.642 0.358 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.641 0.359 0.000
K83.9 Disease of biliary tract, unspecified
0.641 0.359 0.000
K83.5 Biliary cyst
0.641 0.359 0.000
K83.4 Spasm of sphincter of Oddi
0.641 0.359 0.000
K83.3 Fistula of bile duct
0.641 0.359 0.000
K83.2 Perforation of bile duct
0.641 0.359 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.641 0.359 0.000
S21 Open wound of thorax
0.640 0.359 0.000
F39 Unspecified mood [affective] disorder
0.640 0.360 0.000
M25.9 Joint disorder, unspecified
0.640 0.360 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.639 0.360 0.000
H73 Other disorders of tympanic membrane
0.639 0.361 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.638 0.362 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.638 0.362 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.638 0.362 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.638 0.362 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.638 0.362 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.638 0.362 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.638 0.362 0.000
S70-S79 Injuries to the hip and thigh
0.638 0.362 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.638 0.362 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.638 0.362 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.638 0.362 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.638 0.362 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.638 0.362 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.638 0.362 0.000
M40-M43 Deforming dorsopathies
0.637 0.363 0.000
Y57.8 Other drugs and medicaments
0.637 0.363 0.000
T51.9 Alcohol, unspecified
0.637 0.363 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.636 0.364 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.636 0.364 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.636 0.364 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.635 0.364 0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified
0.635 0.365 0.000
H95.8 Other postprocedural disorders of ear and mastoid process
0.635 0.365 0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity
0.635 0.365 0.000
S19 Other and unspecified injuries of neck
0.635 0.365 0.000
T79-T79 Certain early complications of trauma
0.635 0.365 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.635 0.365 0.000
H80-H83 Diseases of inner ear
0.634 0.366 0.000
T66-T78 Other and unspecified effects of external causes
0.634 0.366 0.000
H50.9 Strabismus, unspecified
0.634 0.366 0.000
M24.5 Contracture of joint
0.634 0.366 0.000
X20-X29 Contact with venomous animals and plants
0.634 0.366 0.000
M84.9 Disorder of continuity of bone, unspecified
0.634 0.366 0.000
M84.8 Other disorders of continuity of bone
0.634 0.366 0.000
M84.3 Stress fracture, not elsewhere classified
0.634 0.366 0.000
M84.2 Delayed union of fracture
0.634 0.366 0.000
K83.8 Other specified diseases of biliary tract
0.633 0.367 0.000
T00 Superficial injuries involving multiple body regions
0.632 0.368 0.000
M14 Arthropathies in other diseases classified elsewhere
0.631 0.368 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.629 0.371 0.000
H11 Other disorders of conjunctiva
0.629 0.371 0.000
M07 Psoriatic and enteropathic arthropathies
0.628 0.371 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.628 0.372 0.000
H49 Paralytic strabismus
0.628 0.372 0.000
Chapter VI Diseases of the nervous system
0.628 0.372 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.628 0.372 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.627 0.373 0.000
H60.0 Abscess of external ear
0.627 0.373 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.626 0.373 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.626 0.373 0.000
U80 Agent resistant to penicillin and related antibiotics
0.626 0.374 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.625 0.375 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.624 0.375 0.000
W21 Striking against or struck by sports equipment
0.624 0.376 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.623 0.376 0.000
Y52 Agents primarily affecting the cardiovascular system
0.623 0.377 0.000
T43.9 Psychotropic drug, unspecified
0.623 0.377 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.623 0.377 0.000
T43.6 Psychostimulants with abuse potential
0.623 0.377 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.623 0.377 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.623 0.377 0.000
T56 Toxic effect of metals
0.623 0.377 0.000
H16 Keratitis
0.622 0.378 0.000
H59.8 Other postprocedural disorders of eye and adnexa
0.622 0.378 0.000
H74.0 Tympanosclerosis
0.621 0.379 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.621 0.379 0.000
M05 Seropositive rheumatoid arthritis
0.620 0.380 0.000
T91.3 Sequelae of injury of spinal cord
0.620 0.380 0.000
S48 Traumatic amputation of shoulder and upper arm
0.620 0.380 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.620 0.380 0.000
S44 Injury of nerves at shoulder and upper arm level
0.620 0.380 0.000
S47 Crushing injury of shoulder and upper arm
0.620 0.380 0.000
T62 Toxic effect of other noxious substances eaten as food
0.619 0.380 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.619 0.380 0.000
T60 Toxic effect of pesticides
0.619 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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