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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62331196
log Bayes Factor = 13.0231
Chromosome 4   position 105,185,596  (GRCh37) Explore rs62331196 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.997 0.003 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.995 0.005 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.994 0.006 0.000
Chapter XXI Factors influencing health status and contact with health services
0.994 0.006 0.000
R50-R69 General symptoms and signs
0.993 0.007 0.000
E20-E35 Disorders of other endocrine glands
0.991 0.009 0.000
R55 Syncope and collapse
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.985 0.015 0.000
R69 Unknown and unspecified causes of morbidity
0.981 0.019 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.972 0.028 0.000
S00-S09 Injuries to the head
0.967 0.033 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.962 0.038 0.000
C78.0 Secondary malignant neoplasm of lung
0.954 0.046 0.000
Chapter IX Diseases of the circulatory system
0.951 0.049 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.947 0.053 0.000
Chapter I Certain infectious and parasitic diseases
0.946 0.054 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.946 0.054 0.000
S01 Open wound of head
0.944 0.056 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.943 0.057 0.000
S20-S29 Injuries to the thorax
0.939 0.061 0.000
S40-S49 Injuries to the shoulder and upper arm
0.938 0.062 0.000
I60-I69 Cerebrovascular diseases
0.938 0.062 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.937 0.063 0.000
E70-E90 Metabolic disorders
0.936 0.064 0.000
T43.2 Other and unspecified antidepressants
0.934 0.066 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.934 0.066 0.000
Z13 Special screening examination for other diseases and disorders
0.933 0.067 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.931 0.069 0.000
R00 Abnormalities of heart beat
0.925 0.075 0.000
C15-C26 Malignant neoplasms of digestive organs
0.919 0.081 0.000
E86 Volume depletion
0.918 0.082 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.916 0.084 0.000
E27 Other disorders of adrenal gland
0.914 0.086 0.000
Chapter XI Diseases of the digestive system
0.910 0.090 0.000
C51-C58 Malignant neoplasms of female genital organs
0.906 0.094 0.000
S80-S89 Injuries to the knee and lower leg
0.905 0.095 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.903 0.097 0.000
K50-K52 Noninfective enteritis and colitis
0.902 0.098 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.900 0.100 0.000
K52 Other non-infective gastro-enteritis and colitis
0.899 0.101 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.897 0.103 0.000
C78.2 Secondary malignant neoplasm of pleura
0.896 0.104 0.000
Chapter V Mental and behavioural disorders
0.895 0.105 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.894 0.106 0.000
S42 Fracture of shoulder and upper arm
0.892 0.108 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.887 0.113 0.000
Z12 Special screening examination for neoplasms
0.886 0.114 0.000
R00.1 Bradycardia, unspecified
0.882 0.118 0.000
E10-E14 Diabetes mellitus
0.880 0.120 0.000
I63 Cerebral infarction
0.876 0.124 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.876 0.124 0.000
E23 Hypofunction and other disorders of pituitary gland
0.876 0.124 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.875 0.125 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.874 0.126 0.000
D70 Agranulocytosis
0.873 0.127 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.866 0.134 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.865 0.135 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.865 0.135 0.000
B35-B49 Mycoses
0.864 0.136 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.856 0.144 0.000
R00.0 Tachycardia, unspecified
0.852 0.148 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.849 0.151 0.000
D00-D09 In situ neoplasms
0.848 0.152 0.000
E21.0 Primary hyperparathyroidism
0.848 0.152 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.847 0.153 0.000
S01.2 Open wound of nose
0.846 0.154 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.846 0.154 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.844 0.156 0.000
W00-W19 Falls
0.842 0.158 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.842 0.158 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.841 0.159 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.835 0.165 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.834 0.166 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.831 0.169 0.000
T39.1 4-Aminophenol derivatives
0.830 0.170 0.000
I69 Sequelae of cerebrovascular disease
0.826 0.174 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.825 0.175 0.000
C45 Mesothelioma
0.824 0.176 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.823 0.177 0.000
C78.7 Secondary malignant neoplasm of liver
0.823 0.177 0.000
S01.1 Open wound of eyelid and periocular area
0.820 0.180 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.818 0.181 0.000
E27.1 Primary adrenocortical insufficiency
0.818 0.182 0.000
S01.8 Open wound of other parts of head
0.815 0.185 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.814 0.186 0.000
S50-S59 Injuries to the elbow and forearm
0.813 0.187 0.000
C16 Malignant neoplasm of stomach
0.812 0.188 0.000
R73 Elevated blood glucose level
0.812 0.188 0.000
K55-K64 Other diseases of intestines
0.811 0.189 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.810 0.190 0.000
B37 Candidiasis
0.810 0.190 0.000
A30-A49 Other bacterial diseases
0.809 0.191 0.000
Y43 Primarily systemic agents
0.808 0.192 0.000
Z13.5 Special screening examination for eye and ear disorders
0.805 0.195 0.000
C56 Malignant neoplasm of ovary
0.802 0.198 0.000
S27 Injury of other and unspecified intrathoracic organs
0.802 0.198 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.802 0.198 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.799 0.201 0.000
S22.4 Multiple fractures of ribs
0.797 0.203 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.796 0.204 0.000
R59 Enlarged lymph nodes
0.794 0.205 0.000
E21.3 Hyperparathyroidism, unspecified
0.793 0.207 0.000
R00.2 Palpitations
0.793 0.207 0.000
C90.0 Multiple myeloma
0.791 0.209 0.000
R76 Other abnormal immunological findings in serum
0.790 0.210 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.786 0.214 0.000
Z13.1 Special screening examination for diabetes mellitus
0.785 0.215 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.784 0.216 0.000
C53 Malignant neoplasm of cervix uteri
0.784 0.216 0.000
E11 Non-insulin-dependent diabetes mellitus
0.783 0.217 0.000
T40.2 Other opioids
0.782 0.218 0.000
S02 Fracture of skull and facial bones
0.782 0.218 0.000
S10-S19 Injuries to the neck
0.782 0.218 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.782 0.218 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.781 0.219 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.780 0.220 0.000
R54 Senility
0.779 0.221 0.000
Y95 Nosocomial condition
0.777 0.223 0.000
I63.9 Cerebral infarction, unspecified
0.776 0.224 0.000
Z00.0 General medical examination
0.774 0.226 0.000
Chapter XXII Codes for special purposes
0.773 0.226 0.000
S42.1 Fracture of scapula
0.772 0.228 0.000
E24 Cushing's syndrome
0.769 0.231 0.000
E14 Unspecified diabetes mellitus
0.769 0.231 0.000
Y84.0 Cardiac catheterisation
0.767 0.233 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.765 0.234 0.000
S01.0 Open wound of scalp
0.765 0.235 0.000
R77 Other abnormalities of plasma proteins
0.765 0.235 0.000
E27.2 Addisonian crisis
0.764 0.236 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.763 0.237 0.000
V80-V89 Other land transport accidents
0.762 0.238 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.762 0.238 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.761 0.239 0.000
A80-A89 Viral infections of the central nervous system
0.760 0.239 0.000
C64-C68 Malignant neoplasms of urinary tract
0.760 0.240 0.000
Y52 Agents primarily affecting the cardiovascular system
0.760 0.240 0.000
X60-X84 Intentional self-harm
0.759 0.241 0.000
S42.4 Fracture of lower end of humerus
0.759 0.241 0.000
R06 Abnormalities of breathing
0.758 0.242 0.000
C80 Malignant neoplasm without specification of site
0.758 0.242 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.756 0.244 0.000
S22.40 Multiple fractures of ribs (closed)
0.755 0.245 0.000
S83.2 Tear of meniscus, current
0.755 0.245 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.755 0.245 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.753 0.247 0.000
Z29 Need for other prophylactic measures
0.753 0.247 0.000
S90-S99 Injuries to the ankle and foot
0.752 0.248 0.000
S05 Injury of eye and orbit
0.752 0.248 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.751 0.249 0.000
I05-I09 Chronic rheumatic heart diseases
0.751 0.249 0.000
I61 Intracerebral haemorrhage
0.751 0.249 0.000
R01 Cardiac murmurs and other cardiac sounds
0.749 0.251 0.000
R50 Fever of unknown origin
0.747 0.253 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.747 0.253 0.000
R47-R49 Symptoms and signs involving speech and voice
0.745 0.255 0.000
K61 Abscess of anal and rectal regions
0.744 0.256 0.000
S01.5 Open wound of lip and oral cavity
0.744 0.256 0.000
Z03.1 Observation for suspected malignant neoplasm
0.743 0.257 0.000
Y84.8 Other medical procedures
0.742 0.258 0.000
I73 Other peripheral vascular diseases
0.740 0.260 0.000
Z02 Examination and encounter for administrative purposes
0.739 0.261 0.000
C91 Lymphoid leukaemia
0.738 0.262 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.737 0.263 0.000
W20-W49 Exposure to inanimate mechanical forces
0.737 0.263 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.735 0.265 0.000
C44 Other malignant neoplasms of skin
0.735 0.265 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.735 0.265 0.000
E00-E07 Disorders of thyroid gland
0.734 0.266 0.000
C20 Malignant neoplasm of rectum
0.734 0.266 0.000
I65.2 Occlusion and stenosis of carotid artery
0.733 0.267 0.000
E85 Amyloidosis
0.733 0.267 0.000
C15 Malignant neoplasm of oesophagus
0.733 0.267 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.732 0.267 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.732 0.268 0.000
R61 Hyperhidrosis
0.731 0.269 0.000
S09 Other and unspecified injuries of head
0.731 0.269 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.730 0.270 0.000
F30-F39 Mood [affective] disorders
0.729 0.271 0.000
S29 Other and unspecified injuries of thorax
0.729 0.271 0.000
R56 Convulsions, not elsewhere classified
0.728 0.272 0.000
C18 Malignant neoplasm of colon
0.727 0.273 0.000
Z03.4 Observation for suspected myocardial infarction
0.724 0.276 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.723 0.276 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.723 0.276 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.723 0.277 0.000
K52.1 Toxic gastro-enteritis and colitis
0.723 0.277 0.000
D73 Diseases of spleen
0.722 0.278 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.721 0.279 0.000
D68 Other coagulation defects
0.721 0.279 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.721 0.279 0.000
E23.7 Disorder of pituitary gland, unspecified
0.720 0.280 0.000
E40-E46 Malnutrition
0.719 0.281 0.000
S42.0 Fracture of clavicle
0.719 0.281 0.000
D72 Other disorders of white blood cells
0.719 0.281 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.718 0.282 0.000
C21 Malignant neoplasm of anus and anal canal
0.718 0.282 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.717 0.283 0.000
E28 Ovarian dysfunction
0.716 0.284 0.000
K63 Other diseases of intestine
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.284 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.715 0.285 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.715 0.285 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
R73.9 Hyperglycaemia, unspecified
0.714 0.286 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.714 0.286 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.286 0.000
C25 Malignant neoplasm of pancreas
0.713 0.287 0.000
Z10 Routine general health check-up of defined subpopulation
0.713 0.287 0.000
B15-B19 Viral hepatitis
0.713 0.287 0.000
Y43.3 Other antineoplastic drugs
0.713 0.287 0.000
C45.9 Mesothelioma, unspecified
0.713 0.287 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.712 0.288 0.000
R62 Lack of expected normal physiological development
0.712 0.288 0.000
R64 Cachexia
0.712 0.288 0.000
R58 Haemorrhage, not elsewhere classified
0.712 0.288 0.000
E11.3 With ophthalmic complications
0.711 0.289 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.710 0.290 0.000
E34 Other endocrine disorders
0.710 0.290 0.000
E32 Diseases of thymus
0.710 0.290 0.000
E31 Polyglandular dysfunction
0.710 0.290 0.000
E30 Disorders of puberty, not elsewhere classified
0.710 0.290 0.000
E26 Hyperaldosteronism
0.710 0.290 0.000
E25 Adrenogenital disorders
0.710 0.290 0.000
E20 Hypoparathyroidism
0.710 0.290 0.000
R09.2 Respiratory arrest
0.710 0.290 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.709 0.291 0.000
E14.9 Without complications
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.708 0.292 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.707 0.293 0.000
E23.0 Hypopituitarism
0.707 0.293 0.000
F43 Reaction to severe stress, and adjustment disorders
0.707 0.293 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.706 0.294 0.000
E22 Hyperfunction of pituitary gland
0.706 0.294 0.000
E88 Other metabolic disorders
0.706 0.294 0.000
C45.0 Mesothelioma of pleura
0.705 0.295 0.000
V10-V19 Pedal cyclist injured in transport accident
0.705 0.295 0.000
S42.2 Fracture of upper end of humerus
0.705 0.295 0.000
E29 Testicular dysfunction
0.704 0.296 0.000
Z22 Carrier of infectious disease
0.704 0.296 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.703 0.297 0.000
R09.1 Pleurisy
0.702 0.298 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.701 0.299 0.000
C90.2 Plasmacytoma, extramedullary
0.701 0.299 0.000
S81 Open wound of lower leg
0.701 0.299 0.000
T40.4 Other synthetic narcotics
0.701 0.299 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.299 0.000
I60 Subarachnoid haemorrhage
0.700 0.300 0.000
S40 Superficial injury of shoulder and upper arm
0.699 0.301 0.000
R79 Other abnormal findings of blood chemistry
0.699 0.301 0.000
B37.0 Candidal stomatitis
0.698 0.302 0.000
K70-K77 Diseases of liver
0.698 0.302 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.698 0.302 0.000
T43.9 Psychotropic drug, unspecified
0.697 0.303 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.697 0.303 0.000
T43.6 Psychostimulants with abuse potential
0.697 0.303 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.697 0.303 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.697 0.303 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.697 0.303 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
E50-E64 Other nutritional deficiencies
0.696 0.304 0.000
C53.9 Cervix uteri, unspecified
0.696 0.304 0.000
S01.3 Open wound of ear
0.695 0.305 0.000
D03 Melanoma in situ
0.695 0.305 0.000
S70-S79 Injuries to the hip and thigh
0.695 0.305 0.000
C16.5 Lesser curvature of stomach, unspecified
0.695 0.305 0.000
D05 Carcinoma in situ of breast
0.694 0.306 0.000
R52 Pain, not elsewhere classified
0.694 0.306 0.000
S08 Traumatic amputation of part of head
0.693 0.307 0.000
S07 Crushing injury of head
0.693 0.307 0.000
S04 Injury of cranial nerves
0.693 0.307 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.693 0.307 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.693 0.307 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.691 0.308 0.000
R74 Abnormal serum enzyme levels
0.691 0.309 0.000
I73.0 Raynaud's syndrome
0.691 0.309 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.690 0.310 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.690 0.310 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.690 0.310 0.000
R71 Abnormality of red blood cells
0.690 0.310 0.000
D75 Other diseases of blood and blood-forming organs
0.687 0.312 0.000
I67 Other cerebrovascular diseases
0.686 0.314 0.000
S42.10 Fracture of scapula (closed)
0.685 0.315 0.000
E23.2 Diabetes insipidus
0.685 0.315 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.685 0.315 0.000
C44.5 Skin of trunk
0.683 0.317 0.000
C44.1 Skin of eyelid, including canthus
0.683 0.317 0.000
I00-I02 Acute rheumatic fever
0.682 0.318 0.000
Y84.6 Urinary catheterisation
0.682 0.318 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.681 0.319 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.680 0.320 0.000
B99-B99 Other infectious diseases
0.679 0.321 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.679 0.321 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.679 0.321 0.000
B65-B83 Helminthiases
0.679 0.321 0.000
B50-B64 Protozoal diseases
0.679 0.321 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.679 0.321 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.679 0.321 0.000
A75-A79 Rickettsioses
0.679 0.321 0.000
A70-A74 Other diseases caused by chlamydiae
0.679 0.321 0.000
A65-A69 Other spirochaetal diseases
0.679 0.321 0.000
A20-A28 Certain zoonotic bacterial diseases
0.679 0.321 0.000
A15-A19 Tuberculosis
0.679 0.321 0.000
D55-D59 Haemolytic anaemias
0.678 0.321 0.000
R57 Shock, not elsewhere classified
0.678 0.322 0.000
B37.8 Candidiasis of other sites
0.678 0.322 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.678 0.322 0.000
S01.7 Multiple open wounds of head
0.677 0.323 0.000
S01.4 Open wound of cheek and temporomandibular area
0.677 0.323 0.000
V20-V29 Motorcycle rider injured in transport accident
0.676 0.324 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.676 0.324 0.000
K56.6 Other and unspecified intestinal obstruction
0.676 0.324 0.000
K58 Irritable bowel syndrome
0.676 0.324 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.675 0.325 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.673 0.326 0.000
S26 Injury of heart
0.673 0.326 0.000
S25 Injury of blood vessels of thorax
0.673 0.326 0.000
S24 Injury of nerves and spinal cord at thorax level
0.673 0.326 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.673 0.326 0.000
S21 Open wound of thorax
0.673 0.326 0.000
S48 Traumatic amputation of shoulder and upper arm
0.673 0.327 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.673 0.327 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.673 0.327 0.000
S44 Injury of nerves at shoulder and upper arm level
0.673 0.327 0.000
S41 Open wound of shoulder and upper arm
0.673 0.327 0.000
S47 Crushing injury of shoulder and upper arm
0.673 0.327 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.673 0.327 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.673 0.327 0.000
F60-F69 Disorders of adult personality and behaviour
0.672 0.328 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.672 0.328 0.000
E84 Cystic fibrosis
0.671 0.329 0.000
E79 Disorders of purine and pyrimidine metabolism
0.671 0.329 0.000
E77 Disorders of glycoprotein metabolism
0.671 0.329 0.000
E76 Disorders of glycosaminoglycan metabolism
0.671 0.329 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.671 0.329 0.000
E74 Other disorders of carbohydrate metabolism
0.671 0.329 0.000
E73 Lactose intolerance
0.671 0.329 0.000
E72 Other disorders of amino-acid metabolism
0.671 0.329 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.671 0.329 0.000
E70 Disorders of aromatic amino-acid metabolism
0.671 0.329 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.671 0.329 0.000
B00 Herpesviral [herpes simplex] infections
0.671 0.329 0.000
S06 Intracranial injury
0.670 0.330 0.000
A41 Other septicaemia
0.670 0.330 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.670 0.330 0.000
C95 Leukaemia of unspecified cell type
0.670 0.330 0.000
C94 Other leukaemias of specified cell type
0.670 0.330 0.000
C93 Monocytic leukaemia
0.670 0.330 0.000
C88 Malignant immunoproliferative diseases
0.670 0.330 0.000
C86 Other specified types of T/NK-cell lymphoma
0.670 0.330 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.670 0.330 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.669 0.331 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.669 0.331 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.669 0.331 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.669 0.331 0.000
Z13.2 Special screening examination for nutritional disorders
0.669 0.331 0.000
Y84.1 Kidney dialysis
0.667 0.332 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.667 0.333 0.000
E21.4 Other specified disorders of parathyroid gland
0.667 0.333 0.000
E21.2 Other hyperparathyroidism
0.667 0.333 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.667 0.333 0.000
R76.8 Other specified abnormal immunological findings in serum
0.667 0.333 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.665 0.335 0.000
C16.0 Cardia
0.665 0.335 0.000
Chapter X Diseases of the respiratory system
0.664 0.336 0.000
S42.40 Fracture of lower end of humerus (closed)
0.663 0.337 0.000
R06.4 Hyperventilation
0.662 0.338 0.000
T23 Burn and corrosion of wrist and hand
0.662 0.338 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.661 0.339 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.661 0.339 0.000
I95 Hypotension
0.661 0.339 0.000
S52 Fracture of forearm
0.660 0.340 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.660 0.340 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.659 0.341 0.000
S22.0 Fracture of thoracic vertebra
0.659 0.341 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.659 0.341 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.659 0.341 0.000
C17 Malignant neoplasm of small intestine
0.659 0.341 0.000
C23 Malignant neoplasm of gallbladder
0.659 0.341 0.000
Z04 Examination and observation for other reasons
0.658 0.342 0.000
Y44 Agents primarily affecting blood constituents
0.657 0.343 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.657 0.343 0.000
D74 Methaemoglobinaemia
0.657 0.343 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.657 0.343 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.657 0.343 0.000
K63.3 Ulcer of intestine
0.657 0.343 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.656 0.344 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.656 0.344 0.000
E27.9 Disorder of adrenal gland, unspecified
0.655 0.345 0.000
E27.8 Other specified disorders of adrenal gland
0.655 0.345 0.000
E27.5 Adrenomedullary hyperfunction
0.655 0.345 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.655 0.345 0.000
E27.0 Other adrenocortical overactivity
0.655 0.345 0.000
S27.2 Traumatic heamopneumothorax
0.655 0.345 0.000
B37.9 Candidiasis, unspecified
0.655 0.345 0.000
W17 Other fall from one level to another
0.654 0.346 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.654 0.346 0.000
C18.9 Colon, unspecified
0.653 0.347 0.000
Z29.2 Other prophylactic chemotherapy
0.653 0.347 0.000
Y40 Systemic antibiotics
0.652 0.348 0.000
F41 Other anxiety disorders
0.651 0.349 0.000
S27.0 Traumatic pneumothorax
0.651 0.349 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.651 0.349 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.650 0.350 0.000
C51 Malignant neoplasm of vulva
0.650 0.350 0.000
C58 Malignant neoplasm of placenta
0.650 0.350 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.650 0.350 0.000
C52 Malignant neoplasm of vagina
0.650 0.350 0.000
S02.2 Fracture of nasal bones
0.650 0.350 0.000
Chapter VIII Diseases of the ear and mastoid process
0.649 0.351 0.000
K61.0 Anal abscess
0.649 0.351 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.649 0.351 0.000
S89 Other and unspecified injuries of lower leg
0.649 0.351 0.000
S88 Traumatic amputation of lower leg
0.649 0.351 0.000
S87 Crushing injury of lower leg
0.649 0.351 0.000
S86 Injury of muscle and tendon at lower leg level
0.649 0.351 0.000
S85 Injury of blood vessels at lower leg level
0.649 0.351 0.000
S84 Injury of nerves at lower leg level
0.649 0.351 0.000
K63.2 Fistula of intestine
0.649 0.351 0.000
F31 Bipolar affective disorder
0.648 0.352 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.647 0.353 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.647 0.353 0.000
C46 Kaposi's sarcoma
0.647 0.353 0.000
W10 Fall on and from stairs and steps
0.647 0.353 0.000
I20-I25 Ischaemic heart diseases
0.646 0.354 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.645 0.355 0.000
K52.3 Indeterminate colitis
0.645 0.355 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.645 0.355 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.645 0.355 0.000
R09.0 Asphyxia
0.643 0.357 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.642 0.358 0.000
F80-F89 Disorders of psychological development
0.642 0.358 0.000
F70-F79 Mental retardation
0.642 0.358 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.641 0.359 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.641 0.359 0.000
Y59 Other and unspecified vaccines and biological substances
0.641 0.359 0.000
Y58 Bacterial vaccines
0.641 0.359 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.641 0.359 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.641 0.359 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.641 0.359 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.641 0.359 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.641 0.359 0.000
Y48 Anaesthetics and therapeutic gases
0.641 0.359 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.641 0.359 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.641 0.359 0.000
D04 Carcinoma in situ of skin
0.640 0.360 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.639 0.360 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.639 0.360 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.639 0.360 0.000
K65-K67 Diseases of peritoneum
0.639 0.361 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.639 0.361 0.000
Z13.9 Special screening examination, unspecified
0.638 0.362 0.000
K61.3 Ischiorectal abscess
0.638 0.362 0.000
F43.2 Adjustment disorders
0.638 0.362 0.000
E11.4 With neurological complications
0.638 0.362 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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