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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62354080
log Bayes Factor = 15.2122
Chromosome 4   position 188,370,696  (GRCh37) Explore rs62354080 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.993 0.007 0.000
Chapter VI Diseases of the nervous system
0.993 0.007 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.990 0.010 0.000
C15-C26 Malignant neoplasms of digestive organs
0.981 0.019 0.000
S00-S09 Injuries to the head
0.980 0.020 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.978 0.022 0.000
Chapter VII Diseases of the eye and adnexa
0.975 0.025 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.972 0.028 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.970 0.030 0.000
W00-W19 Falls
0.965 0.035 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.959 0.041 0.000
G20-G26 Extrapyramidal and movement disorders
0.959 0.041 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.958 0.042 0.000
C78.0 Secondary malignant neoplasm of lung
0.958 0.042 0.000
C79 Secondary malignant neoplasm of other sites
0.954 0.046 0.000
Chapter X Diseases of the respiratory system
0.944 0.056 0.000
Chapter I Certain infectious and parasitic diseases
0.943 0.057 0.000
C78.7 Secondary malignant neoplasm of liver
0.941 0.059 0.000
S00 Superficial injury of head
0.939 0.061 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.938 0.062 0.000
Z50 Care involving use of rehabilitation procedures
0.936 0.064 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.935 0.065 0.000
S70-S79 Injuries to the hip and thigh
0.929 0.071 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.925 0.075 0.000
W19 Unspecified fall
0.925 0.075 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.919 0.081 0.000
Chapter XI Diseases of the digestive system
0.916 0.084 0.000
B95-B98 Bacterial, viral and other infectious agents
0.914 0.086 0.000
Z51 Other medical care
0.911 0.089 0.000
F10.2 Dependence syndrome
0.908 0.092 0.000
G20 Parkinson's disease
0.903 0.097 0.000
F30-F39 Mood [affective] disorders
0.902 0.098 0.000
S80-S89 Injuries to the knee and lower leg
0.899 0.101 0.000
Z92 Personal history of medical treatment
0.899 0.101 0.000
D10-D36 Benign neoplasms
0.898 0.102 0.000
J30-J39 Other diseases of upper respiratory tract
0.898 0.102 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.896 0.104 0.000
C18 Malignant neoplasm of colon
0.895 0.105 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.894 0.106 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.894 0.106 0.000
H43-H45 Disorders of vitreous body and globe
0.892 0.108 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.891 0.109 0.000
K31 Other diseases of stomach and duodenum
0.890 0.110 0.000
Z53.0 Procedure not carried out because of contraindication
0.889 0.111 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.885 0.115 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.884 0.116 0.000
Z46 Fitting and adjustment of other devices
0.883 0.117 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.881 0.119 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.881 0.119 0.000
Y40 Systemic antibiotics
0.880 0.120 0.000
Z50.8 Care involving use of rehabilitation procedures
0.875 0.125 0.000
O60-O75 Complications of labour and delivery
0.873 0.127 0.000
W19.4 Street and highway
0.873 0.127 0.000
Z51.5 Palliative care
0.872 0.128 0.000
K31.7 Polyp of stomach and duodenum
0.870 0.130 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.870 0.130 0.000
Chapter VIII Diseases of the ear and mastoid process
0.870 0.130 0.000
J34 Other disorders of nose and nasal sinuses
0.870 0.130 0.000
S00.8 Superficial injury of other parts of head
0.862 0.138 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.861 0.139 0.000
S72 Fracture of femur
0.861 0.139 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.859 0.140 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.857 0.143 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.857 0.143 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.855 0.145 0.000
G40-G47 Episodic and paroxysmal disorders
0.855 0.145 0.000
Z92.3 Personal history of irradiation
0.853 0.147 0.000
K70-K77 Diseases of liver
0.852 0.148 0.000
Z88.2 Personal history of allergy to sulphonamides
0.849 0.151 0.000
S01 Open wound of head
0.848 0.152 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.844 0.156 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.843 0.157 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.840 0.160 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.833 0.167 0.000
F10.0 Acute intoxication
0.830 0.170 0.000
C25 Malignant neoplasm of pancreas
0.829 0.171 0.000
Z80 Family history of malignant neoplasm
0.829 0.171 0.000
G24 Dystonia
0.826 0.174 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.825 0.175 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.825 0.175 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.824 0.176 0.000
C50-C50 Malignant neoplasm of breast
0.824 0.176 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.821 0.179 0.000
Z47 Other orthopaedic follow-up care
0.820 0.180 0.000
S72.0 Fracture of neck of femur
0.815 0.185 0.000
C22.1 Intrahepatic bile duct carcinoma
0.815 0.185 0.000
S09 Other and unspecified injuries of head
0.814 0.186 0.000
D23 Other benign neoplasms of skin
0.814 0.186 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.814 0.186 0.000
H55-H59 Other disorders of eye and adnexa
0.813 0.187 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.811 0.189 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.810 0.190 0.000
F31 Bipolar affective disorder
0.809 0.191 0.000
A30-A49 Other bacterial diseases
0.807 0.193 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.806 0.194 0.000
S90-S99 Injuries to the ankle and foot
0.805 0.195 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.805 0.195 0.000
F10.1 Harmful use
0.803 0.196 0.000
Y43 Primarily systemic agents
0.803 0.197 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.801 0.199 0.000
Chapter XXII Codes for special purposes
0.801 0.199 0.000
J34.2 Deviated nasal septum
0.800 0.200 0.000
S20-S29 Injuries to the thorax
0.800 0.200 0.000
Y52 Agents primarily affecting the cardiovascular system
0.799 0.201 0.000
S00.9 Superficial injury of head, part unspecified
0.797 0.203 0.000
F10.3 Withdrawal state
0.793 0.207 0.000
Q60-Q64 Congenital malformations of the urinary system
0.790 0.210 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.787 0.213 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.786 0.214 0.000
K22 Other diseases of oesophagus
0.786 0.214 0.000
O00-O08 Pregnancy with abortive outcome
0.785 0.215 0.000
C18.7 Sigmoid colon
0.785 0.215 0.000
S72.00 Fracture of neck of femur (closed)
0.782 0.218 0.000
Z46.6 Fitting and adjustment of urinary device
0.782 0.218 0.000
W19.9 Unspecified place
0.780 0.220 0.000
J40-J47 Chronic lower respiratory diseases
0.780 0.220 0.000
J00-J06 Acute upper respiratory infections
0.780 0.220 0.000
Y40.0 Penicillins
0.779 0.221 0.000
H60-H62 Diseases of external ear
0.776 0.224 0.000
H43 Disorders of vitreous body
0.776 0.224 0.000
Z88.6 Personal history of allergy to analgesic agent
0.776 0.224 0.000
Z49 Care involving dialysis
0.775 0.225 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.773 0.227 0.000
Z96 Presence of other functional implants
0.773 0.227 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.773 0.227 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.772 0.228 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.772 0.228 0.000
C15 Malignant neoplasm of oesophagus
0.770 0.230 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.769 0.231 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.769 0.231 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.768 0.232 0.000
G81 Hemiplegia
0.767 0.233 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.765 0.235 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.764 0.236 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.764 0.236 0.000
H53-H54 Visual disturbances and blindness
0.764 0.236 0.000
H44 Disorders of globe
0.763 0.237 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.762 0.238 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.761 0.239 0.000
C60-C63 Malignant neoplasms of male genital organs
0.756 0.244 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.756 0.244 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.755 0.245 0.000
K76 Other diseases of liver
0.754 0.246 0.000
W07 Fall involving chair
0.754 0.246 0.000
K31.8 Other specified diseases of stomach and duodenum
0.754 0.246 0.000
C09 Malignant neoplasm of tonsil
0.752 0.248 0.000
Z93 Artificial opening status
0.752 0.248 0.000
D00-D09 In situ neoplasms
0.751 0.249 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.751 0.249 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.751 0.249 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.748 0.252 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.748 0.252 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.748 0.252 0.000
S80 Superficial injury of lower leg
0.746 0.254 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.746 0.254 0.000
O36 Maternal care for other known or suspected foetal problems
0.742 0.258 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.741 0.259 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.741 0.259 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.740 0.260 0.000
T81 Complications of procedures, not elsewhere classified
0.739 0.261 0.000
K50-K52 Noninfective enteritis and colitis
0.739 0.261 0.000
G70-G73 Diseases of myoneural junction and muscle
0.739 0.261 0.000
D23.7 Skin of lower limb, including hip
0.737 0.263 0.000
Y44 Agents primarily affecting blood constituents
0.737 0.263 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.737 0.263 0.000
S89 Other and unspecified injuries of lower leg
0.735 0.265 0.000
S50-S59 Injuries to the elbow and forearm
0.735 0.265 0.000
S70 Superficial injury of hip and thigh
0.734 0.266 0.000
C79.2 Secondary malignant neoplasm of skin
0.733 0.266 0.000
Z50.2 Alcohol rehabilitation
0.733 0.267 0.000
Z45 Adjustment and management of implanted device
0.732 0.268 0.000
S01.2 Open wound of nose
0.732 0.268 0.000
G24.9 Dystonia, unspecified
0.732 0.268 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.731 0.268 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.730 0.270 0.000
W20-W49 Exposure to inanimate mechanical forces
0.730 0.270 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.730 0.270 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.729 0.271 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.729 0.271 0.000
C10 Malignant neoplasm of oropharynx
0.729 0.271 0.000
W06 Fall involving bed
0.728 0.272 0.000
Y86 Sequelae of other accidents
0.728 0.272 0.000
T86 Failure and rejection of transplanted organs and tissues
0.726 0.274 0.000
J34.3 Hypertrophy of nasal turbinates
0.726 0.274 0.000
J32 Chronic sinusitis
0.725 0.275 0.000
T66-T78 Other and unspecified effects of external causes
0.724 0.276 0.000
S32 Fracture of lumbar spine and pelvis
0.724 0.276 0.000
O41 Other disorders of amniotic fluid and membranes
0.724 0.276 0.000
C18.2 Ascending colon
0.723 0.277 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.723 0.277 0.000
W13 Fall from, out of or through building or structure
0.722 0.278 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.722 0.278 0.000
Z80.3 Family history of malignant neoplasm of breast
0.721 0.279 0.000
Z43 Attention to artificial openings
0.720 0.280 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.720 0.280 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.719 0.281 0.000
J60-J70 Lung diseases due to external agents
0.719 0.281 0.000
F31.9 Bipolar affective disorder, unspecified
0.719 0.281 0.000
Z92.0 Personal history of contraception
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.716 0.284 0.000
Y57 Other and unspecified drugs and medicaments
0.716 0.284 0.000
G25 Other extrapyramidal and movement disorders
0.716 0.284 0.000
C18.9 Colon, unspecified
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V20-V29 Motorcycle rider injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
C80 Malignant neoplasm without specification of site
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
J40 Bronchitis, not specified as acute or chronic
0.714 0.286 0.000
F99-F99 Unspecified mental disorder
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F80-F89 Disorders of psychological development
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
F60-F69 Disorders of adult personality and behaviour
0.714 0.286 0.000
V10-V19 Pedal cyclist injured in transport accident
0.714 0.286 0.000
K70 Alcoholic liver disease
0.714 0.286 0.000
O47 False labour
0.714 0.286 0.000
Z40 Prophylactic surgery
0.714 0.286 0.000
S81 Open wound of lower leg
0.713 0.287 0.000
F32 Depressive episode
0.712 0.288 0.000
H61 Other disorders of external ear
0.712 0.288 0.000
Z54 Convalescence
0.712 0.288 0.000
Z52 Donors of organs and tissues
0.712 0.288 0.000
Z44 Fitting and adjustment of external prosthetic device
0.712 0.288 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.712 0.288 0.000
O70 Perineal laceration during delivery
0.711 0.289 0.000
D18 Haemangioma and lymphangioma, any site
0.711 0.289 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.710 0.290 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.710 0.290 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.710 0.290 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.710 0.290 0.000
D10 Benign neoplasm of mouth and pharynx
0.709 0.290 0.000
G90-G99 Other disorders of the nervous system
0.709 0.291 0.000
C34 Malignant neoplasm of bronchus and lung
0.708 0.292 0.000
Z87 Personal history of other diseases and conditions
0.708 0.292 0.000
H04 Disorders of lachrymal system
0.707 0.293 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.707 0.293 0.000
Z89 Acquired absence of limb
0.705 0.295 0.000
C22.0 Liver cell carcinoma
0.705 0.295 0.000
D29 Benign neoplasm of male genital organs
0.704 0.296 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.704 0.296 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.704 0.296 0.000
H30-H36 Disorders of choroid and retina
0.704 0.296 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.703 0.297 0.000
C21 Malignant neoplasm of anus and anal canal
0.703 0.297 0.000
C17 Malignant neoplasm of small intestine
0.703 0.297 0.000
C23 Malignant neoplasm of gallbladder
0.703 0.297 0.000
S08 Traumatic amputation of part of head
0.703 0.297 0.000
S07 Crushing injury of head
0.703 0.297 0.000
S05 Injury of eye and orbit
0.703 0.297 0.000
S04 Injury of cranial nerves
0.703 0.297 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.703 0.297 0.000
Z42 Follow-up care involving plastic surgery
0.702 0.297 0.000
Z94 Transplanted organ and tissue status
0.702 0.298 0.000
T59 Toxic effect of other gases, fumes and vapours
0.701 0.299 0.000
O85-O92 Complications predominantly related to the puerperium
0.701 0.299 0.000
D24 Benign neoplasm of breast
0.701 0.299 0.000
D34 Benign neoplasm of thyroid gland
0.700 0.300 0.000
G81.9 Hemiplegia, unspecified
0.700 0.300 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.699 0.301 0.000
Z51.0 Radiotherapy session
0.698 0.302 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.697 0.303 0.000
Y59 Other and unspecified vaccines and biological substances
0.697 0.303 0.000
Y58 Bacterial vaccines
0.697 0.303 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.697 0.303 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.697 0.303 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.697 0.303 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.697 0.303 0.000
Y48 Anaesthetics and therapeutic gases
0.697 0.303 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.697 0.303 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.697 0.303 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
C50 Malignant neoplasm of breast
0.697 0.303 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.696 0.304 0.000
S09.9 Unspecified injury of head
0.696 0.304 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.695 0.304 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.695 0.304 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.695 0.304 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.695 0.304 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.695 0.304 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.695 0.304 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.695 0.304 0.000
F11 Mental and behavioural disorders due to use of opioids
0.695 0.304 0.000
S06 Intracranial injury
0.695 0.305 0.000
D17 Benign lipomatous neoplasm
0.695 0.305 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.694 0.306 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.693 0.307 0.000
H10-H13 Disorders of conjunctiva
0.693 0.307 0.000
O34.1 Maternal care for tumour of corpus uteri
0.692 0.308 0.000
W18 Other fall on same level
0.692 0.308 0.000
W17 Other fall from one level to another
0.692 0.308 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.692 0.308 0.000
W15 Fall from cliff
0.692 0.308 0.000
W14 Fall from tree
0.692 0.308 0.000
W12 Fall on and from scaffolding
0.692 0.308 0.000
W11 Fall on and from ladder
0.692 0.308 0.000
W10 Fall on and from stairs and steps
0.692 0.308 0.000
W09 Fall involving playground equipment
0.692 0.308 0.000
W08 Fall involving other furniture
0.692 0.308 0.000
W05 Fall involving wheelchair
0.692 0.308 0.000
W04 Fall while being carried or supported by other persons
0.692 0.308 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.692 0.308 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.692 0.308 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.692 0.308 0.000
W00 Fall on same level involving ice and snow
0.692 0.308 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.691 0.309 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.691 0.309 0.000
J35 Chronic diseases of tonsils and adenoids
0.690 0.310 0.000
H40-H42 Glaucoma
0.690 0.310 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.690 0.310 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.689 0.310 0.000
C32 Malignant neoplasm of larynx
0.689 0.311 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.689 0.311 0.000
C24.0 Extrahepatic bile duct
0.689 0.311 0.000
Chapter IX Diseases of the circulatory system
0.689 0.311 0.000
Y40.9 Systemic antibiotic, unspecified
0.688 0.312 0.000
Z84 Family history of other conditions
0.688 0.312 0.000
Z81 Family history of mental and behavioural disorders
0.688 0.312 0.000
Z97 Presence of other devices
0.688 0.312 0.000
G23 Other degenerative diseases of basal ganglia
0.687 0.312 0.000
G21 Secondary Parkinsonism
0.687 0.312 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.687 0.312 0.000
G22 Parkinsonism in diseases classified elsewhere
0.687 0.312 0.000
F10.9 Unspecified mental and behavioural disorder
0.687 0.313 0.000
F10.8 Other mental and behavioural disorders
0.687 0.313 0.000
F10.7 Residual and late-onset psychotic disorder
0.687 0.313 0.000
F10.6 Amnesic syndrome
0.687 0.313 0.000
F10.5 Psychotic disorder
0.687 0.313 0.000
F10.4 Withdrawal state with delirium
0.687 0.313 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.687 0.313 0.000
G54 Nerve root and plexus disorders
0.686 0.314 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.686 0.314 0.000
S00.0 Superficial injury of scalp
0.685 0.314 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.685 0.315 0.000
J39 Other diseases of upper respiratory tract
0.685 0.315 0.000
C79.6 Secondary malignant neoplasm of ovary
0.684 0.316 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.684 0.316 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.684 0.316 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.684 0.316 0.000
Y88 Sequelae of surgical and medical care as external cause
0.684 0.316 0.000
K35-K38 Diseases of appendix
0.684 0.316 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.683 0.317 0.000
Y43.3 Other antineoplastic drugs
0.682 0.318 0.000
S01.0 Open wound of scalp
0.681 0.319 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.681 0.319 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.681 0.319 0.000
K22.1 Ulcer of oesophagus
0.681 0.319 0.000
Z53.9 Procedure not carried out, unspecified reason
0.680 0.320 0.000
X60-X84 Intentional self-harm
0.680 0.320 0.000
E70-E90 Metabolic disorders
0.679 0.321 0.000
C25.0 Head of pancreas
0.679 0.321 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.677 0.323 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.677 0.323 0.000
K27 Peptic ulcer, site unspecified
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.676 0.324 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.676 0.324 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.676 0.324 0.000
B65-B83 Helminthiases
0.676 0.324 0.000
B50-B64 Protozoal diseases
0.676 0.324 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.676 0.324 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.676 0.324 0.000
A80-A89 Viral infections of the central nervous system
0.676 0.324 0.000
A75-A79 Rickettsioses
0.676 0.324 0.000
A70-A74 Other diseases caused by chlamydiae
0.676 0.324 0.000
A65-A69 Other spirochaetal diseases
0.676 0.324 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.676 0.324 0.000
A20-A28 Certain zoonotic bacterial diseases
0.676 0.324 0.000
A15-A19 Tuberculosis
0.676 0.324 0.000
K65-K67 Diseases of peritoneum
0.676 0.324 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.674 0.326 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.674 0.326 0.000
Q61 Cystic kidney disease
0.673 0.326 0.000
S00.7 Multiple superficial injuries of head
0.673 0.327 0.000
S00.5 Superficial injury of lip and oral cavity
0.673 0.327 0.000
S00.4 Superficial injury of ear
0.673 0.327 0.000
S00.3 Superficial injury of nose
0.673 0.327 0.000
H54 Blindness and low vision
0.673 0.327 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.673 0.327 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.672 0.327 0.000
J95-J99 Other diseases of the respiratory system
0.672 0.328 0.000
Z50.6 Orthoptic training
0.671 0.329 0.000
Z50.3 Drug rehabilitation
0.671 0.329 0.000
T87 Complications peculiar to reattachment and amputation
0.670 0.329 0.000
F45 Somatoform disorders
0.670 0.330 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.670 0.330 0.000
K21 Gastro-oesophageal reflux disease
0.670 0.330 0.000
S00.1 Contusion of eyelid and periocular area
0.670 0.330 0.000
W19.2 School, other institution and public administrative area
0.669 0.331 0.000
H57 Other disorders of eye and adnexa
0.669 0.331 0.000
Z47.8 Other specified orthopaedic follow-up care
0.668 0.332 0.000
Z51.8 Other specified medical care
0.668 0.332 0.000
Y40.8 Other systemic antibiotics
0.667 0.333 0.000
S79 Other and unspecified injuries of hip and thigh
0.666 0.334 0.000
S78 Traumatic amputation of hip and thigh
0.666 0.334 0.000
S77 Crushing injury of hip and thigh
0.666 0.334 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.666 0.334 0.000
S75 Injury of blood vessels at hip and thigh level
0.666 0.334 0.000
S74 Injury of nerves at hip and thigh level
0.666 0.334 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.666 0.334 0.000
S71 Open wound of hip and thigh
0.666 0.334 0.000
S92 Fracture of foot, except ankle
0.666 0.334 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.665 0.334 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.665 0.334 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.664 0.335 0.000
O45 Premature separation of placenta [abruptio placentae]
0.663 0.336 0.000
O44 Placenta praevia
0.663 0.336 0.000
O43 Placental disorders
0.663 0.336 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.663 0.336 0.000
O33 Maternal care for known or suspected disproportion
0.663 0.336 0.000
O31 Complications specific to multiple gestation
0.663 0.336 0.000
O40 Polyhydramnios
0.663 0.336 0.000
W19.8 Other specified place
0.663 0.337 0.000
W19.5 Trade and service area
0.663 0.337 0.000
W19.0 Home
0.663 0.337 0.000
W19.7 Farm
0.663 0.337 0.000
W19.6 Industrial and construction area
0.663 0.337 0.000
W19.3 Sports and athletics area
0.663 0.337 0.000
W19.1 Residential institution
0.663 0.337 0.000
A41 Other septicaemia
0.663 0.337 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.662 0.337 0.000
I95 Hypotension
0.662 0.338 0.000
H65-H75 Diseases of middle ear and mastoid
0.662 0.338 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.662 0.338 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.662 0.338 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.661 0.338 0.000
G44 Other headache syndromes
0.661 0.339 0.000
C18.6 Descending colon
0.661 0.339 0.000
C25.9 Pancreas, unspecified
0.660 0.340 0.000
T93 Sequelae of injuries of lower limb
0.660 0.340 0.000
J90-J94 Other diseases of pleura
0.660 0.340 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.659 0.341 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.658 0.341 0.000
S20 Superficial injury of thorax
0.658 0.342 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.658 0.342 0.000
O30 Multiple gestation
0.658 0.342 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.658 0.342 0.000
G40 Epilepsy
0.658 0.342 0.000
B15-B19 Viral hepatitis
0.657 0.342 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.657 0.342 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.657 0.343 0.000
C09.9 Tonsil, unspecified
0.657 0.343 0.000
E20-E35 Disorders of other endocrine glands
0.657 0.343 0.000
F33 Recurrent depressive disorder
0.655 0.344 0.000
S01.1 Open wound of eyelid and periocular area
0.653 0.347 0.000
Z51.9 Medical care, unspecified
0.653 0.347 0.000
Z51.6 Desensitisation to allergens
0.653 0.347 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.652 0.348 0.000
A49 Bacterial infection of unspecified site
0.652 0.348 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.652 0.348 0.000
Q63 Other congenital malformations of kidney
0.652 0.348 0.000
F41 Other anxiety disorders
0.651 0.349 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.651 0.349 0.000
K74 Fibrosis and cirrhosis of liver
0.651 0.349 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.650 0.349 0.000
O80-O84 Delivery
0.650 0.350 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.649 0.350 0.000
B35-B49 Mycoses
0.649 0.350 0.000
S02 Fracture of skull and facial bones
0.647 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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