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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62369380
log Bayes Factor = 13.7147
Chromosome 5   position 66,502,384  (GRCh37) Explore rs62369380 on Ensembl!
Variant rs62369380 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.997 0.003 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.996 0.004 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
M05-M14 Inflammatory polyarthropathies
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
I25.1 Atherosclerotic heart disease
0.989 0.011 0.000
M20-M25 Other joint disorders
0.988 0.012 0.000
G40-G47 Episodic and paroxysmal disorders
0.975 0.025 0.000
Chapter II Neoplasms
0.968 0.032 0.000
I21 Acute myocardial infarction
0.965 0.035 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.960 0.040 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.959 0.041 0.000
M10 Gout
0.956 0.044 0.000
G47 Sleep disorders
0.955 0.045 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.955 0.045 0.000
Chapter XX External causes of morbidity and mortality
0.951 0.049 0.000
J44 Other chronic obstructive pulmonary disease
0.950 0.050 0.000
M70-M79 Other soft tissue disorders
0.948 0.052 0.000
M13 Other arthritis
0.940 0.060 0.000
S60-S69 Injuries to the wrist and hand
0.936 0.064 0.000
R00 Abnormalities of heart beat
0.935 0.065 0.000
J45 Asthma
0.933 0.067 0.000
G47.3 Sleep apnoea
0.932 0.068 0.000
M23 Internal derangement of knee
0.929 0.071 0.000
M10.9 Gout, unspecified
0.928 0.072 0.000
I05-I09 Chronic rheumatic heart diseases
0.918 0.082 0.000
J30-J39 Other diseases of upper respiratory tract
0.914 0.086 0.000
I49 Other cardiac arrhythmias
0.914 0.086 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.912 0.088 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.912 0.088 0.000
R06 Abnormalities of breathing
0.910 0.090 0.000
C64-C68 Malignant neoplasms of urinary tract
0.906 0.094 0.000
J40 Bronchitis, not specified as acute or chronic
0.902 0.098 0.000
M13.9 Arthritis, unspecified
0.901 0.099 0.000
R05 Cough
0.900 0.100 0.000
S80-S89 Injuries to the knee and lower leg
0.899 0.101 0.000
M10.99 Gout, unspecified (Site unspecified)
0.897 0.103 0.000
T66-T78 Other and unspecified effects of external causes
0.891 0.109 0.000
I35 Nonrheumatic aortic valve disorders
0.887 0.113 0.000
J47 Bronchiectasis
0.885 0.115 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.884 0.116 0.000
M20 Acquired deformities of fingers and toes
0.881 0.119 0.000
J45.9 Asthma, unspecified
0.880 0.120 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.870 0.130 0.000
I10-I15 Hypertensive diseases
0.869 0.131 0.000
J34 Other disorders of nose and nasal sinuses
0.868 0.132 0.000
I45 Other conduction disorders
0.867 0.133 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.867 0.133 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.866 0.134 0.000
I21.4 Acute subendocardial myocardial infarction
0.865 0.135 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.861 0.139 0.000
J95-J99 Other diseases of the respiratory system
0.859 0.141 0.000
I84 Haemorrhoids
0.858 0.142 0.000
I08 Multiple valve diseases
0.857 0.143 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.857 0.143 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.853 0.147 0.000
C51-C58 Malignant neoplasms of female genital organs
0.851 0.149 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.850 0.150 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.850 0.150 0.000
I42 Cardiomyopathy
0.848 0.152 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.848 0.152 0.000
M06 Other rheumatoid arthritis
0.848 0.152 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.848 0.152 0.000
R00.1 Bradycardia, unspecified
0.847 0.153 0.000
I38 Endocarditis, valve unspecified
0.846 0.154 0.000
I50 Heart failure
0.846 0.154 0.000
I20 Angina pectoris
0.845 0.155 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.845 0.155 0.000
R47-R49 Symptoms and signs involving speech and voice
0.845 0.155 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.843 0.157 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.840 0.160 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.840 0.160 0.000
R00.0 Tachycardia, unspecified
0.839 0.161 0.000
M50-M54 Other dorsopathies
0.839 0.161 0.000
C67 Malignant neoplasm of bladder
0.837 0.163 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.835 0.165 0.000
M22 Disorders of patella
0.832 0.168 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.829 0.171 0.000
M79.8 Other specified soft tissue disorders
0.829 0.171 0.000
D00-D09 In situ neoplasms
0.824 0.176 0.000
S68 Traumatic amputation of wrist and hand
0.821 0.179 0.000
M33 Dermatopolymyositis
0.820 0.180 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.819 0.181 0.000
G90-G99 Other disorders of the nervous system
0.816 0.184 0.000
I21.9 Acute myocardial infarction, unspecified
0.810 0.190 0.000
M20.5 Other deformities of toe(s) (acquired)
0.810 0.190 0.000
J60-J70 Lung diseases due to external agents
0.808 0.192 0.000
I22 Subsequent myocardial infarction
0.807 0.193 0.000
R00.2 Palpitations
0.805 0.195 0.000
G70-G73 Diseases of myoneural junction and muscle
0.799 0.201 0.000
I08.0 Disorders of both mitral and aortic valves
0.799 0.201 0.000
I10 Essential (primary) hypertension
0.798 0.202 0.000
I83 Varicose veins of lower extremities
0.798 0.202 0.000
T79-T79 Certain early complications of trauma
0.797 0.203 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.796 0.204 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.795 0.205 0.000
T78 Adverse effects, not elsewhere classified
0.795 0.205 0.000
S20-S29 Injuries to the thorax
0.794 0.206 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.793 0.207 0.000
I33 Acute and subacute endocarditis
0.793 0.207 0.000
M21 Other acquired deformities of limbs
0.792 0.208 0.000
S50-S59 Injuries to the elbow and forearm
0.791 0.209 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.791 0.209 0.000
W20-W49 Exposure to inanimate mechanical forces
0.791 0.209 0.000
S83.2 Tear of meniscus, current
0.789 0.211 0.000
I49.5 Sick sinus syndrome
0.789 0.211 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.788 0.211 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.785 0.215 0.000
M50 Cervical disk disorders
0.783 0.217 0.000
J32 Chronic sinusitis
0.781 0.219 0.000
Chapter XXII Codes for special purposes
0.779 0.221 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.778 0.222 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.776 0.224 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.775 0.225 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.775 0.225 0.000
I49.9 Cardiac arrhythmia, unspecified
0.772 0.228 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.772 0.228 0.000
M35 Other systemic involvement of connective tissue
0.771 0.229 0.000
I35.8 Other aortic valve disorders
0.769 0.231 0.000
X20-X29 Contact with venomous animals and plants
0.769 0.231 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.769 0.231 0.000
S90-S99 Injuries to the ankle and foot
0.768 0.232 0.000
M20.4 Other hammer toe(s) (acquired)
0.767 0.233 0.000
M15-M19 Arthrosis
0.766 0.234 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.764 0.236 0.000
Y84.0 Cardiac catheterisation
0.764 0.236 0.000
I71 Aortic aneurysm and dissection
0.764 0.236 0.000
J34.2 Deviated nasal septum
0.763 0.237 0.000
S10-S19 Injuries to the neck
0.762 0.238 0.000
G56 Mononeuropathies of upper limb
0.762 0.238 0.000
M23.3 Other meniscus derangements
0.761 0.239 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.760 0.240 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.760 0.240 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.760 0.240 0.000
M05 Seropositive rheumatoid arthritis
0.760 0.240 0.000
D37.5 Rectum
0.758 0.242 0.000
I82 Other venous embolism and thrombosis
0.757 0.243 0.000
I20.0 Unstable angina
0.756 0.244 0.000
I35.0 Aortic (valve) stenosis
0.756 0.244 0.000
M79.6 Pain in limb
0.755 0.245 0.000
R06.2 Wheezing
0.755 0.245 0.000
R47 Speech disturbances, not elsewhere classified
0.754 0.246 0.000
I50.1 Left ventricular failure
0.754 0.246 0.000
I45.1 Other and unspecified right bundle-branch block
0.753 0.247 0.000
I31 Other diseases of pericardium
0.752 0.248 0.000
I86 Varicose veins of other sites
0.750 0.249 0.000
S69 Other and unspecified injuries of wrist and hand
0.749 0.250 0.000
M75 Shoulder lesions
0.748 0.252 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.746 0.254 0.000
I84.1 Internal haemorrhoids with other complications
0.746 0.254 0.000
R07 Pain in throat and chest
0.745 0.255 0.000
R06.8 Other and unspecified abnormalities of breathing
0.744 0.256 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.744 0.256 0.000
M06.9 Rheumatoid arthritis, unspecified
0.743 0.257 0.000
G20-G26 Extrapyramidal and movement disorders
0.742 0.258 0.000
R06.5 Mouth breathing
0.742 0.258 0.000
R06.1 Stridor
0.741 0.258 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.740 0.260 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.739 0.261 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.738 0.262 0.000
C54 Malignant neoplasm of corpus uteri
0.738 0.262 0.000
J43 Emphysema
0.738 0.262 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.738 0.262 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.738 0.262 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.738 0.262 0.000
J36 Peritonsillar abscess
0.737 0.263 0.000
I49.1 Atrial premature depolarisation
0.737 0.263 0.000
M07 Psoriatic and enteropathic arthropathies
0.737 0.263 0.000
M79.0 Rheumatism, unspecified
0.736 0.264 0.000
M23.4 Loose body in knee
0.736 0.264 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.735 0.265 0.000
M13.93 Arthritis, unspecified (Forearm)
0.732 0.268 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.732 0.268 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.732 0.268 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.730 0.270 0.000
O80-O84 Delivery
0.730 0.270 0.000
M65-M68 Disorders of synovium and tendon
0.729 0.270 0.000
M24 Other specific joint derangements
0.729 0.270 0.000
Chapter XIV Diseases of the genitourinary system
0.729 0.271 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.729 0.271 0.000
S81 Open wound of lower leg
0.728 0.272 0.000
J42 Unspecified chronic bronchitis
0.727 0.273 0.000
M86-M90 Other osteopathies
0.726 0.274 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.724 0.276 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.723 0.277 0.000
M80-M85 Disorders of bone density and structure
0.722 0.278 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.722 0.278 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.722 0.278 0.000
I44 Atrioventricular and left bundle-branch block
0.722 0.278 0.000
G47.9 Sleep disorder, unspecified
0.721 0.279 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.720 0.280 0.000
T90 Sequelae of injuries of head
0.720 0.280 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.719 0.281 0.000
M79.5 Residual foreign body in soft tissue
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
I42.9 Cardiomyopathy, unspecified
0.715 0.285 0.000
G56.2 Lesion of ulnar nerve
0.715 0.285 0.000
J41 Simple and mucopurulent chronic bronchitis
0.715 0.285 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I37 Pulmonary valve disorders
0.713 0.287 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
I30 Acute pericarditis
0.713 0.287 0.000
M14 Arthropathies in other diseases classified elsewhere
0.713 0.287 0.000
M12 Other specific arthropathies
0.713 0.287 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.713 0.287 0.000
M08 Juvenile arthritis
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
I27 Other pulmonary heart diseases
0.711 0.289 0.000
R02 Gangrene, not elsewhere classified
0.711 0.289 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.710 0.290 0.000
Y84.2 Radiological procedure and radiotherapy
0.710 0.290 0.000
J45.0 Predominantly allergic asthma
0.710 0.290 0.000
G43 Migraine
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.709 0.290 0.000
M20.3 Other deformity of hallux (acquired)
0.708 0.292 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.708 0.292 0.000
M34 Systemic sclerosis
0.708 0.292 0.000
M32 Systemic lupus erythematosus
0.708 0.292 0.000
M30 Polyarteritis nodosa and related conditions
0.708 0.292 0.000
I84.2 Internal haemorrhoids without complication
0.707 0.293 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.706 0.293 0.000
M22.4 Chondromalacia patellae
0.706 0.294 0.000
M23.8 Other internal derangements of knee
0.706 0.294 0.000
R06.0 Dyspnoea
0.706 0.294 0.000
O00-O08 Pregnancy with abortive outcome
0.705 0.295 0.000
C67.4 Posterior wall of bladder
0.705 0.295 0.000
I49.0 Ventricular fibrillation and flutter
0.704 0.296 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.703 0.297 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.703 0.297 0.000
G45.4 Transient global amnesia
0.702 0.298 0.000
M33.2 Polymyositis
0.700 0.300 0.000
I05 Rheumatic mitral valve diseases
0.700 0.300 0.000
M79.67 Pain in limb (Ankle and foot)
0.700 0.300 0.000
I77 Other disorders of arteries and arterioles
0.699 0.301 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.699 0.301 0.000
G41 Status epilepticus
0.699 0.301 0.000
D37.4 Colon
0.698 0.301 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.698 0.302 0.000
Q60-Q64 Congenital malformations of the urinary system
0.698 0.302 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.698 0.302 0.000
R09.2 Respiratory arrest
0.698 0.302 0.000
I50.9 Heart failure, unspecified
0.697 0.303 0.000
I74 Arterial embolism and thrombosis
0.697 0.303 0.000
M20.0 Deformity of finger(s)
0.697 0.303 0.000
T68 Hypothermia
0.697 0.303 0.000
G40 Epilepsy
0.696 0.304 0.000
S70-S79 Injuries to the hip and thigh
0.695 0.305 0.000
C81 Hodgkin's disease
0.695 0.305 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.694 0.306 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.694 0.306 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.694 0.306 0.000
M13.98 Arthritis, unspecified (Other)
0.694 0.306 0.000
M79.1 Myalgia
0.693 0.307 0.000
I34 Nonrheumatic mitral valve disorders
0.692 0.308 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.692 0.308 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.692 0.308 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.691 0.308 0.000
M31 Other necrotising vasculopathies
0.691 0.309 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.690 0.309 0.000
J98 Other respiratory disorders
0.690 0.310 0.000
I35.1 Aortic (valve) insufficiency
0.690 0.310 0.000
I84.0 Internal thrombosed haemorrhoids
0.689 0.311 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.689 0.311 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.689 0.311 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.688 0.311 0.000
M50.2 Other cervical disk displacement
0.689 0.311 0.000
M75.4 Impingement syndrome of shoulder
0.688 0.312 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.688 0.312 0.000
I84.3 External thrombosed haemorrhoids
0.687 0.313 0.000
O82 Single delivery by Caesarean section
0.687 0.313 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.686 0.314 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.686 0.314 0.000
M10.4 Other secondary gout
0.685 0.315 0.000
M10.3 Gout due to impairment of renal function
0.685 0.315 0.000
M10.2 Drug-induced gout
0.685 0.315 0.000
M10.1 Lead-induced gout
0.685 0.315 0.000
M10.0 Idiopathic gout
0.685 0.315 0.000
G47.8 Other sleep disorders
0.685 0.315 0.000
G47.4 Narcolepsy and cataplexy
0.685 0.315 0.000
G47.2 Disorders of the sleep-wake schedule
0.685 0.315 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.685 0.315 0.000
I88 Nonspecific lymphadenitis
0.685 0.315 0.000
R07.4 Chest pain, unspecified
0.685 0.315 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.684 0.316 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.683 0.316 0.000
C67.2 Lateral wall of bladder
0.683 0.317 0.000
X60-X84 Intentional self-harm
0.683 0.317 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.682 0.318 0.000
J39 Other diseases of upper respiratory tract
0.682 0.318 0.000
N60-N64 Disorders of breast
0.682 0.318 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.681 0.318 0.000
Y35-Y36 Legal intervention and operations of war
0.681 0.318 0.000
Y10-Y34 Event of undetermined intent
0.681 0.318 0.000
Y00-Y09 Assault
0.681 0.318 0.000
X85-X99 Assault
0.681 0.318 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.681 0.318 0.000
X50-X57 Overexertion, travel and privation
0.681 0.318 0.000
X30-X39 Exposure to forces of nature
0.681 0.318 0.000
X10-X19 Contact with heat and hot substances
0.681 0.318 0.000
X00-X09 Exposure to smoke, fire and flames
0.681 0.318 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.681 0.318 0.000
W75-W84 Other accidental threats to breathing
0.681 0.318 0.000
W65-W74 Accidental drowning and submersion
0.681 0.318 0.000
W50-W64 Exposure to animate mechanical forces
0.681 0.318 0.000
V98-V99 Other and unspecified transport accidents
0.681 0.318 0.000
V95-V97 Air and space transport accidents
0.681 0.318 0.000
V90-V94 Water transport accidents
0.681 0.318 0.000
V80-V89 Other land transport accidents
0.681 0.318 0.000
V70-V79 Bus occupant injured in transport accident
0.681 0.318 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.681 0.318 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.681 0.318 0.000
V40-V49 Car occupant injured in transport accident
0.681 0.318 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.681 0.318 0.000
V01-V09 Pedestrian injured in transport accident
0.681 0.318 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.681 0.319 0.000
Chapter VIII Diseases of the ear and mastoid process
0.681 0.319 0.000
I85 Oesophageal varices
0.681 0.319 0.000
I81 Portal vein thrombosis
0.680 0.319 0.000
M76 Enthesopathies of lower limb, excluding foot
0.680 0.320 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.680 0.320 0.000
M71 Other bursopathies
0.680 0.320 0.000
S60 Superficial injury of wrist and hand
0.674 0.326 0.000
M13.8 Other specified arthritis
0.674 0.326 0.000
M13.1 Monoarthritis, not elsewhere classified
0.674 0.326 0.000
M13.0 Polyarthritis, unspecified
0.674 0.326 0.000
V20-V29 Motorcycle rider injured in transport accident
0.674 0.326 0.000
I87 Other disorders of veins
0.673 0.327 0.000
R47.8 Other and unspecified speech disturbances
0.673 0.327 0.000
M23.5 Chronic instability of knee
0.672 0.328 0.000
C34 Malignant neoplasm of bronchus and lung
0.672 0.328 0.000
D05 Carcinoma in situ of breast
0.672 0.328 0.000
R09.1 Pleurisy
0.671 0.329 0.000
J32.9 Chronic sinusitis, unspecified
0.671 0.329 0.000
C67.6 Ureteric orifice
0.671 0.329 0.000
S67 Crushing injury of wrist and hand
0.671 0.329 0.000
S65 Injury of blood vessels at wrist and hand level
0.671 0.329 0.000
J69 Pneumonitis due to solids and liquids
0.671 0.329 0.000
S61 Open wound of wrist and hand
0.671 0.329 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.670 0.330 0.000
C67.1 Dome of bladder
0.670 0.330 0.000
J45.8 Mixed asthma
0.669 0.331 0.000
J45.1 Nonallergic asthma
0.669 0.331 0.000
R26 Abnormalities of gait and mobility
0.669 0.331 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.667 0.333 0.000
T78.4 Allergy, unspecified
0.667 0.333 0.000
I49.4 Other and unspecified premature depolarisation
0.666 0.334 0.000
M23.9 Internal derangement of knee, unspecified
0.666 0.334 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.666 0.334 0.000
M23.1 Discoid meniscus (congenital)
0.666 0.334 0.000
M23.0 Cystic meniscus
0.666 0.334 0.000
M10.98 Gout, unspecified (Other)
0.665 0.335 0.000
M10.96 Gout, unspecified (Lower leg)
0.665 0.335 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.665 0.335 0.000
M10.94 Gout, unspecified (Hand)
0.665 0.335 0.000
M10.93 Gout, unspecified (Forearm)
0.665 0.335 0.000
M10.92 Gout, unspecified (Upper arm)
0.665 0.335 0.000
M10.91 Gout, unspecified (Shoulder region)
0.665 0.335 0.000
M10.90 Gout, unspecified (Multiple sites)
0.665 0.335 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.665 0.335 0.000
I24 Other acute ischaemic heart diseases
0.664 0.336 0.000
D04 Carcinoma in situ of skin
0.663 0.337 0.000
M22.2 Patellofemoral disorders
0.663 0.337 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.663 0.337 0.000
I20.8 Other forms of angina pectoris
0.662 0.338 0.000
J09-J18 Influenza and pneumonia
0.662 0.338 0.000
I27.0 Primary pulmonary hypertension
0.662 0.338 0.000
V10-V19 Pedal cyclist injured in transport accident
0.661 0.338 0.000
I84.4 External haemorrhoids with other complications
0.661 0.339 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.661 0.339 0.000
C71 Malignant neoplasm of brain
0.660 0.340 0.000
I09 Other rheumatic heart diseases
0.658 0.341 0.000
I06 Rheumatic aortic valve diseases
0.658 0.341 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.658 0.342 0.000
C54.1 Endometrium
0.657 0.342 0.000
M11 Other crystal arthropathies
0.657 0.343 0.000
J34.3 Hypertrophy of nasal turbinates
0.657 0.343 0.000
M50.1 Cervical disk disorder with radiculopathy
0.657 0.343 0.000
J32.2 Chronic ethmoidal sinusitis
0.657 0.343 0.000
R27 Other lack of coordination
0.656 0.343 0.000
M50.0 Cervical disk disorder with myelopathy
0.656 0.344 0.000
J37 Chronic laryngitis and laryngotracheitis
0.655 0.344 0.000
J35 Chronic diseases of tonsils and adenoids
0.655 0.345 0.000
I84.6 Residual haemorrhoidal skin tags
0.655 0.345 0.000
I49.2 Junctional premature depolarisation
0.655 0.345 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.655 0.345 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.654 0.346 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.654 0.346 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.654 0.346 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.654 0.346 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.654 0.346 0.000
M79.9 Soft tissue disorder, unspecified
0.654 0.346 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.654 0.346 0.000
M79.3 Panniculitis, unspecified
0.654 0.346 0.000
M79.2 Neuralgia and neuritis, unspecified
0.654 0.346 0.000
I20.1 Angina pectoris with documented spasm
0.653 0.347 0.000
R06.7 Sneezing
0.652 0.348 0.000
R06.6 Hiccough
0.652 0.348 0.000
R06.3 Periodic breathing
0.652 0.348 0.000
M35.0 Sicca syndrome [Sjogren]
0.652 0.348 0.000
G57 Mononeuropathies of lower limb
0.652 0.348 0.000
D37.7 Other digestive organs
0.650 0.349 0.000
G30-G32 Other degenerative diseases of the nervous system
0.650 0.350 0.000
I45.6 Preexcitation syndrome
0.650 0.350 0.000
I25.5 Ischaemic cardiomyopathy
0.649 0.350 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.650 0.350 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.649 0.350 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.649 0.350 0.000
C66 Malignant neoplasm of ureter
0.649 0.350 0.000
C65 Malignant neoplasm of renal pelvis
0.649 0.350 0.000
I42.2 Other hypertrophic cardiomyopathy
0.649 0.351 0.000
Y84.6 Urinary catheterisation
0.649 0.351 0.000
I51 Complications and ill-defined descriptions of heart disease
0.649 0.351 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.648 0.352 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.648 0.352 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.648 0.352 0.000
I33.0 Acute and subacute infective endocarditis
0.648 0.352 0.000
T91 Sequelae of injuries of neck and trunk
0.648 0.352 0.000
G93 Other disorders of brain
0.647 0.353 0.000
R01 Cardiac murmurs and other cardiac sounds
0.647 0.353 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.647 0.353 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.647 0.353 0.000
J81 Pulmonary oedema
0.647 0.353 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.647 0.353 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.646 0.354 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.646 0.354 0.000
S52 Fracture of forearm
0.646 0.354 0.000
T14 Injury of unspecified body region
0.645 0.355 0.000
G72 Other myopathies
0.644 0.355 0.000
S89 Other and unspecified injuries of lower leg
0.644 0.356 0.000
S88 Traumatic amputation of lower leg
0.644 0.356 0.000
S87 Crushing injury of lower leg
0.644 0.356 0.000
S86 Injury of muscle and tendon at lower leg level
0.644 0.356 0.000
S85 Injury of blood vessels at lower leg level
0.644 0.356 0.000
S84 Injury of nerves at lower leg level
0.644 0.356 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.644 0.356 0.000
I70 Atherosclerosis
0.643 0.357 0.000
I45.5 Other specified heart block
0.643 0.357 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.643 0.357 0.000
Q80-Q89 Other congenital malformations
0.642 0.358 0.000
Y84.1 Kidney dialysis
0.642 0.358 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.641 0.359 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.641 0.359 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.641 0.359 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.640 0.360 0.000
O04 Medical abortion
0.640 0.360 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.640 0.360 0.000
I80 Phlebitis and thrombophlebitis
0.639 0.361 0.000
T75 Effects of other external causes
0.639 0.361 0.000
T74 Maltreatment syndromes
0.639 0.361 0.000
T73 Effects of other deprivation
0.639 0.361 0.000
T70 Effects of air pressure and water pressure
0.639 0.361 0.000
T69 Other effects of reduced temperature
0.639 0.361 0.000
T67 Effects of heat and light
0.639 0.361 0.000
T71 Asphyxiation
0.639 0.361 0.000
T66 Unspecified effects of radiation
0.639 0.361 0.000
X23 Contact with hornets, wasps and bees
0.639 0.361 0.000
R09.0 Asphyxia
0.639 0.361 0.000
N61 Inflammatory disorders of breast
0.639 0.361 0.000
G44 Other headache syndromes
0.638 0.361 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.638 0.362 0.000
M77 Other enthesopathies
0.638 0.362 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.638 0.362 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.637 0.363 0.000
C53 Malignant neoplasm of cervix uteri
0.637 0.363 0.000
J46 Status asthmaticus
0.637 0.363 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.636 0.364 0.000
J20-J22 Other acute lower respiratory infections
0.636 0.364 0.000
I35.9 Aortic valve disorder, unspecified
0.636 0.364 0.000
I72 Other aneurysm
0.634 0.366 0.000
R06.4 Hyperventilation
0.633 0.367 0.000
W25 Contact with sharp glass
0.633 0.367 0.000
Y52 Agents primarily affecting the cardiovascular system
0.632 0.367 0.000
M21.0 Valgus deformity, not elsewhere classified
0.632 0.368 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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