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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs629001
log Bayes Factor = 14.3666
Chromosome 1   position 109,838,918  (GRCh37) Explore rs629001 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
I30-I52 Other forms of heart disease
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I50 Heart failure
0.000 0.001 0.999
I50.0 Congestive heart failure
0.000 0.005 0.995
I20 Angina pectoris
0.000 0.006 0.994
I74 Arterial embolism and thrombosis
0.000 0.017 0.983
I73 Other peripheral vascular diseases
0.000 0.022 0.978
I20.0 Unstable angina
0.000 0.024 0.976
I73.9 Peripheral vascular disease, unspecified
0.000 0.026 0.974
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.028 0.972
I25.2 Old myocardial infarction
0.000 0.029 0.971
I20.9 Angina pectoris, unspecified
0.000 0.031 0.969
I10-I15 Hypertensive diseases
0.000 0.034 0.966
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.038 0.962
I35 Nonrheumatic aortic valve disorders
0.000 0.043 0.957
I35.0 Aortic (valve) stenosis
0.000 0.049 0.951
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.061 0.939
I50.9 Heart failure, unspecified
0.000 0.061 0.939
E78.5 Hyperlipidaemia, unspecified
0.000 0.072 0.928
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.074 0.926
I71 Aortic aneurysm and dissection
0.000 0.077 0.923
I77 Other disorders of arteries and arterioles
0.000 0.089 0.911
I10 Essential (primary) hypertension
0.000 0.098 0.902
I21 Acute myocardial infarction
0.000 0.114 0.886
I12 Hypertensive renal disease
0.000 0.122 0.878
I25.3 Aneurysm of heart
0.000 0.145 0.855
I05-I09 Chronic rheumatic heart diseases
0.000 0.163 0.837
I42 Cardiomyopathy
0.000 0.166 0.834
I46 Cardiac arrest
0.000 0.170 0.830
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.174 0.826
I38 Endocarditis, valve unspecified
0.000 0.177 0.823
I50.1 Left ventricular failure
0.000 0.181 0.819
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.183 0.817
I47 Paroxysmal tachycardia
0.000 0.190 0.810
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.192 0.808
I74.5 Embolism and thrombosis of iliac artery
0.000 0.206 0.794
I45 Other conduction disorders
0.000 0.213 0.787
I21.4 Acute subendocardial myocardial infarction
0.000 0.215 0.785
I12.9 Hypertensive renal disease without renal failure
0.000 0.227 0.773
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.231 0.769
I47.1 Supraventricular tachycardia
0.000 0.238 0.762
I33 Acute and subacute endocarditis
0.000 0.242 0.757
I42.9 Cardiomyopathy, unspecified
0.000 0.246 0.754
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.250 0.750
I77.1 Stricture of artery
0.000 0.255 0.745
I25.5 Ischaemic cardiomyopathy
0.000 0.256 0.744
I77.6 Arteritis, unspecified
0.000 0.257 0.743
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.260 0.740
I77.8 Other specified disorders of arteries and arterioles
0.000 0.262 0.738
I35.8 Other aortic valve disorders
0.000 0.262 0.738
I46.0 Cardiac arrest with successful resuscitation
0.000 0.262 0.738
I45.1 Other and unspecified right bundle-branch block
0.000 0.265 0.735
I49 Other cardiac arrhythmias
0.000 0.266 0.734
I12.0 Hypertensive renal disease with renal failure
0.000 0.272 0.728
I36 Nonrheumatic tricuspid valve disorders
0.000 0.277 0.723
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.279 0.721
I31 Other diseases of pericardium
0.000 0.280 0.720
I07 Rheumatic tricuspid valve diseases
0.000 0.280 0.719
I25.4 Coronary artery aneurysm
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
I52 Other heart disorders in diseases classified elsewhere
0.000 0.283 0.717
I48 Atrial fibrillation and flutter
0.000 0.283 0.717
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.283 0.717
I41 Myocarditis in diseases classified elsewhere
0.000 0.283 0.717
I40 Acute myocarditis
0.000 0.283 0.717
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.283 0.717
I32 Pericarditis in diseases classified elsewhere
0.000 0.283 0.717
I71.0 Dissection of aorta [any part]
0.000 0.292 0.708
I37 Pulmonary valve disorders
0.000 0.293 0.707
I74.8 Embolism and thrombosis of other arteries
0.000 0.295 0.705
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.295 0.705
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.295 0.705
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.295 0.705
I42.8 Other cardiomyopathies
0.000 0.297 0.703
I73.8 Other specified peripheral vascular diseases
0.000 0.299 0.701
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.299 0.701
I13 Hypertensive heart and renal disease
0.000 0.307 0.693
I05 Rheumatic mitral valve diseases
0.000 0.307 0.693
I23 Certain current complications following acute myocardial infarction
0.000 0.308 0.692
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.314 0.686
I77.0 Arteriovenous fistula, acquired
0.000 0.324 0.676
I15 Secondary hypertension
0.000 0.324 0.676
E78.6 Lipoprotein deficiency
0.000 0.326 0.673
E78.3 Hyperchylomicronaemia
0.000 0.326 0.673
E78.1 Pure hyperglyceridaemia
0.000 0.326 0.673
I51 Complications and ill-defined descriptions of heart disease
0.000 0.331 0.669
I11 Hypertensive heart disease
0.000 0.332 0.667
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.338 0.662
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.338 0.662
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.338 0.662
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.338 0.662
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.341 0.659
I49.8 Other specified cardiac arrhythmias
0.000 0.342 0.658
I20.1 Angina pectoris with documented spasm
0.000 0.345 0.655
I77.5 Necrosis of artery
0.000 0.347 0.653
I77.4 Coeliac artery compression syndrome
0.000 0.347 0.653
I77.3 Arterial fibromuscular dysplasia
0.000 0.347 0.653
I77.2 Rupture of artery
0.000 0.347 0.653
I42.2 Other hypertrophic cardiomyopathy
0.000 0.357 0.643
I24 Other acute ischaemic heart diseases
0.000 0.360 0.640
E78.4 Other hyperlipidaemia
0.000 0.362 0.638
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.364 0.636
I07.1 Tricuspid insufficiency
0.000 0.365 0.635
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.370 0.630
I45.3 Trifascicular block
0.000 0.373 0.627
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.380 0.620
I21.9 Acute myocardial infarction, unspecified
0.000 0.392 0.608
I72 Other aneurysm
0.000 0.393 0.607
I35.9 Aortic valve disorder, unspecified
0.000 0.394 0.606
I05.9 Mitral valve disease, unspecified
0.000 0.394 0.606
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.396 0.604
I09 Other rheumatic heart diseases
0.000 0.400 0.600
I06 Rheumatic aortic valve diseases
0.000 0.400 0.600
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.402 0.598
I42.5 Other restrictive cardiomyopathy
0.000 0.402 0.598
I42.4 Endocardial fibroelastosis
0.000 0.402 0.598
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.402 0.598
I46.1 Sudden cardiac death, so described
0.000 0.405 0.595
E78.8 Other disorders of lipoprotein metabolism
0.000 0.406 0.593
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.411 0.589
I49.0 Ventricular fibrillation and flutter
0.000 0.412 0.588
I33.0 Acute and subacute infective endocarditis
0.000 0.416 0.584
I78 Diseases of capillaries
0.000 0.422 0.578
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.423 0.577
I45.5 Other specified heart block
0.000 0.435 0.565
I45.8 Other specified conduction disorders
0.000 0.435 0.564
I45.0 Right fascicular block
0.000 0.435 0.564
I42.6 Alcoholic cardiomyopathy
0.000 0.439 0.561
I31.3 Pericardial effusion (noninflammatory)
0.000 0.441 0.559
I51.7 Cardiomegaly
0.000 0.445 0.555
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.448 0.551
I79.1 Aortitis in diseases classified elsewhere
0.000 0.448 0.551
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.448 0.551
I33.9 Acute endocarditis, unspecified
0.000 0.457 0.543
I49.5 Sick sinus syndrome
0.000 0.462 0.538
I47.0 Reentry ventricular arrhythmia
0.000 0.464 0.536
I45.4 Nonspecific intraventricular block
0.000 0.466 0.534
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.468 0.532
I05.2 Mitral stenosis with insufficiency
0.000 0.470 0.530
I49.1 Atrial premature depolarisation
0.000 0.471 0.529
I49.2 Junctional premature depolarisation
0.000 0.474 0.526
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.476 0.524
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.476 0.524
I45.2 Bifascicular block
0.000 0.476 0.524
I46.9 Cardiac arrest, unspecified
0.000 0.478 0.522
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.482 0.518
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.482 0.518
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.482 0.518
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.482 0.518
I22 Subsequent myocardial infarction
0.000 0.482 0.518
I31.8 Other specified diseases of pericardium
0.000 0.484 0.516
I31.2 Haemopericardium, not elsewhere classified
0.000 0.484 0.516
I31.1 Chronic constrictive pericarditis
0.000 0.484 0.516
I31.0 Chronic adhesive pericarditis
0.000 0.484 0.516
I07.9 Tricuspid valve disease, unspecified
0.000 0.484 0.516
I07.8 Other tricuspid valve diseases
0.000 0.484 0.516
I07.2 Tricuspid stenosis with insufficiency
0.000 0.484 0.516
I07.0 Tricuspid stenosis
0.000 0.484 0.516
I02 Rheumatic chorea
0.000 0.486 0.514
I01 Rheumatic fever with heart involvement
0.000 0.486 0.514
I00 Rheumatic fever without mention of heart involvement
0.000 0.486 0.514
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.486 0.514
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.486 0.514
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.486 0.514
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I40.9 Acute myocarditis, unspecified
0.000 0.486 0.514
I40.8 Other acute myocarditis
0.000 0.486 0.514
I40.1 Isolated myocarditis
0.000 0.486 0.514
I40.0 Infective myocarditis
0.000 0.486 0.514
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.486 0.514
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.486 0.514
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.486 0.514
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.486 0.514
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.486 0.514
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.486 0.514
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.486 0.514
I48.4 Atypical atrial flutter
0.000 0.486 0.514
I48.3 Typical atrial flutter
0.000 0.486 0.514
I48.2 Chronic atrial fibrillation
0.000 0.486 0.514
I48.1 Persistent atrial fibrillation
0.000 0.486 0.514
I48.0 Paroxysmal atrial fibrillation
0.000 0.486 0.514
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.486 0.514
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.486 0.514
I51.8 Other ill-defined heart diseases
0.000 0.488 0.512
I24.8 Other forms of acute ischaemic heart disease
0.000 0.488 0.512
I37.9 Pulmonary valve disorder, unspecified
0.000 0.493 0.507
I37.8 Other pulmonary valve disorders
0.000 0.493 0.507
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.493 0.507
I37.0 Pulmonary valve stenosis
0.000 0.493 0.507
I70 Atherosclerosis
0.001 0.498 0.502
I37.1 Pulmonary valve insufficiency
0.000 0.503 0.497
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.503 0.497
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.503 0.497
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.503 0.497
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.503 0.497
I05.8 Other mitral valve diseases
0.000 0.503 0.497
I05.1 Rheumatic mitral insufficiency
0.000 0.503 0.497
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.503 0.496
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.503 0.496
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.503 0.496
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.503 0.496
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.503 0.496
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.503 0.496
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.503 0.496
E78.2 Mixed hyperlipidaemia
0.000 0.509 0.491
I51.6 Cardiovascular disease, unspecified
0.000 0.513 0.487
I30 Acute pericarditis
0.001 0.514 0.485
I49.3 Ventricular premature depolarisation
0.000 0.515 0.485
I51.0 Cardiac septal defect, acquired
0.000 0.515 0.485
I15.9 Seconday hypertension, unspecified
0.000 0.515 0.485
I15.8 Other secondary hypertension
0.000 0.515 0.485
I15.2 Hypertension secondary to endocrine disorders
0.000 0.515 0.485
I15.0 Renovascular hypertension
0.000 0.515 0.485
I51.5 Myocardial degeneration
0.000 0.520 0.479
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.520 0.479
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.521 0.479
I23.8 Other current complications following acute myocardial infarction
0.000 0.528 0.472
I15.1 Hypertension secondary to other renal disorders
0.000 0.532 0.468
I31.9 Disease of pericardium, unspecified
0.000 0.534 0.466
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.535 0.464
I24.1 Dressler's syndrome
0.000 0.541 0.459
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.546 0.454
I51.9 Heart disease, unspecified
0.000 0.546 0.454
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.547 0.453
I08 Multiple valve diseases
0.000 0.550 0.450
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.559 0.441
I72.9 Aneurysm of unspecified site
0.000 0.564 0.435
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.564 0.435
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.564 0.435
I72.2 Aneurysm of renal artery
0.000 0.564 0.435
I72.1 Aneurysm of artery of upper extremity
0.000 0.564 0.435
I72.3 Aneurysm of iliac artery
0.000 0.568 0.431
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.570 0.430
I06.8 Other rheumatic aortic valve diseases
0.000 0.570 0.430
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.570 0.430
I06.1 Rheumatic aortic insufficiency
0.000 0.570 0.430
I06.0 Rheumatic aortic stenosis
0.000 0.570 0.430
I09.9 Rheumatic heart disease, unspecified
0.000 0.570 0.430
I09.8 Other specified rheumatic heart diseases
0.000 0.570 0.430
I09.2 Chronic rheumatic pericarditis
0.000 0.570 0.430
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.570 0.430
I09.0 Rheumatic myocarditis
0.000 0.570 0.430
I72.4 Aneurysm of artery of lower extremity
0.000 0.570 0.430
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.577 0.423
I27 Other pulmonary heart diseases
0.000 0.578 0.422
I78.9 Disease of capillaries, unspecified
0.000 0.585 0.415
I78.8 Other diseases of capillaries
0.000 0.585 0.415
I28 Other diseases of pulmonary vessels
0.000 0.586 0.414
I05.0 Mitral stenosis
0.000 0.588 0.411
I72.0 Aneurysm of carotid artery
0.000 0.591 0.409
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.592 0.407
I45.9 Conduction disorder, unspecified
0.000 0.595 0.404
I49.4 Other and unspecified premature depolarisation
0.000 0.596 0.404
I20.8 Other forms of angina pectoris
0.000 0.597 0.402
I45.6 Preexcitation syndrome
0.000 0.600 0.400
I35.2 Aortic (valve) stenosis with insufficiency
0.001 0.604 0.396
I72.8 Aneurysm of other specified arteries
0.000 0.622 0.377
I47.2 Ventricular tachycardia
0.000 0.627 0.373
I22.8 Subsequent myocardial infarction of other sites
0.000 0.627 0.373
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.631 0.369
I01.8 Other acute rheumatic heart disease
0.000 0.631 0.369
I01.2 Acute rheumatic myocarditis
0.000 0.631 0.369
I01.1 Acute rheumatic endocarditis
0.000 0.631 0.369
I01.0 Acute rheumatic pericarditis
0.000 0.631 0.369
I02.9 Rheumatic chorea without heart involvement
0.000 0.631 0.369
I02.0 Rheumatic chorea with heart involvement
0.000 0.631 0.369
I27.0 Primary pulmonary hypertension
0.000 0.634 0.366
I51.4 Myocarditis, unspecified
0.000 0.635 0.365
I70.9 Generalised and unspecified atherosclerosis
0.001 0.640 0.360
I70.8 Atherosclerosis of other arteries
0.001 0.640 0.360
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.643 0.357
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.645 0.355
I30.8 Other forms of acute pericarditis
0.001 0.651 0.348
I30.0 Acute nonspecific idiopathic pericarditis
0.001 0.651 0.348
I35.1 Aortic (valve) insufficiency
0.000 0.656 0.344
I70.1 Atherosclerosis of renal artery
0.001 0.656 0.343
I34 Nonrheumatic mitral valve disorders
0.000 0.659 0.341
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.662 0.338
I30.1 Infective pericarditis
0.001 0.673 0.326
I08.9 Multiple valve disease, unspecified
0.000 0.677 0.323
I49.9 Cardiac arrhythmia, unspecified
0.000 0.686 0.314
I70.0 Atherosclerosis of aorta
0.001 0.686 0.313
I08.8 Other multiple valve diseases
0.000 0.688 0.312
I42.0 Dilated cardiomyopathy
0.000 0.689 0.311
I27.8 Other specified pulmonary heart diseases
0.000 0.691 0.308
I27.1 Kyphoscoliotic heart disease
0.000 0.697 0.303
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.700 0.300
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.700 0.300
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.703 0.297
I28.8 Other specified diseases of pulmonary vessels
0.000 0.703 0.297
I28.1 Aneurysm of pulmonary artery
0.000 0.703 0.297
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.703 0.297
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.711 0.289
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.716 0.284
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.718 0.282
I27.2 Other secondary pulmonary hypertension
0.000 0.718 0.282
I86 Varicose veins of other sites
0.000 0.736 0.264
I70.2 Atherosclerosis of arteries of the extremities
0.001 0.738 0.261
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.738 0.261
I70.81 Atherosclerosis of other arteries (with gangrene)
0.001 0.741 0.258
I70.80 Atherosclerosis of other arteries (without gangrene)
0.001 0.741 0.258
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.001 0.741 0.258
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.001 0.741 0.258
I26 Pulmonary embolism
0.000 0.742 0.258
I34.1 Mitral (valve) prolapse
0.000 0.744 0.256
I70.11 Atherosclerosis of renal artery (with gangrene)
0.001 0.753 0.246
I86.1 Scrotal varices
0.000 0.757 0.243
I44 Atrioventricular and left bundle-branch block
0.000 0.758 0.242
I80 Phlebitis and thrombophlebitis
0.000 0.762 0.238
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.769 0.230
I99 Other and unspecified disorders of circulatory system
0.000 0.770 0.230
I08.0 Disorders of both mitral and aortic valves
0.000 0.770 0.230
I70.01 Atherosclerosis of aorta (with gangrene)
0.001 0.775 0.224
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.777 0.223
I78.1 Naevus, nonneoplastic
0.000 0.781 0.219
I27.9 Pulmonary heart disease, unspecified
0.000 0.790 0.210
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.792 0.207
I88 Nonspecific lymphadenitis
0.000 0.794 0.206
I86.4 Gastric varices
0.000 0.796 0.204
I83 Varicose veins of lower extremities
0.000 0.800 0.200
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.801 0.199
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.804 0.196
I44.6 Other and unspecified fascicular block
0.000 0.807 0.193
I86.3 Vulval varices
0.000 0.810 0.189
I86.2 Pelvic varices
0.000 0.810 0.189
I86.0 Sublingual varices
0.000 0.810 0.189
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.001 0.812 0.187
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.812 0.188
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.813 0.187
I86.8 Varicose veins of other specified sites
0.000 0.813 0.187
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.813 0.187
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.815 0.185
I82 Other venous embolism and thrombosis
0.000 0.821 0.179
I70.00 Atherosclerosis of aorta (without gangrene)
0.001 0.822 0.177
I44.5 Left posterior fascicular block
0.000 0.826 0.174
I44.4 Left anterior fascicular block
0.000 0.826 0.174
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.829 0.171
I30.9 Acute pericarditis, unspecified
0.002 0.831 0.167
I44.7 Left bundle-branch block, unspecified
0.000 0.831 0.169
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.832 0.168
I44.1 Atrioventricular block, second degree
0.000 0.833 0.167
I98 Other disorders of circulatory system in diseases classified elsewhere
0.001 0.837 0.162
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.837 0.163
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.838 0.161
J90-J94 Other diseases of pleura
0.000 0.840 0.160
I85 Oesophageal varices
0.000 0.843 0.157
J90 Pleural effusion, not elsewhere classified
0.000 0.843 0.157
J93 Pneumothorax
0.000 0.843 0.157
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.846 0.154
J92 Pleural plaque
0.000 0.848 0.151
I81 Portal vein thrombosis
0.000 0.850 0.150
I88.8 Other nonspecific lymphadenitis
0.000 0.852 0.148
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.852 0.148
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.852 0.148
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.852 0.148
J93.1 Other spontaneous pneumothorax
0.000 0.853 0.147
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.853 0.147
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.853 0.147
J92.9 Pleural plaque without asbestos
0.000 0.854 0.146
J94 Other pleural conditions
0.000 0.855 0.145
I89.0 Lymphoedema, not elsewhere classified
0.000 0.860 0.140
I87 Other disorders of veins
0.000 0.864 0.136
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.864 0.136
J94.8 Other specified pleural conditions
0.000 0.865 0.135
I82.2 Embolism and thrombosis of vena cava
0.000 0.866 0.134
J93.8 Other pneumothorax
0.000 0.869 0.131
J93.9 Pneumothorax, unspecified
0.000 0.870 0.130
I34.0 Mitral (valve) insufficiency
0.000 0.871 0.129
I82.3 Embolism and thrombosis of renal vein
0.000 0.871 0.129
I82.1 Thrombophlebitis migrans
0.000 0.871 0.129
I82.0 Budd-Chiari syndrome
0.000 0.871 0.129
I97.2 Postmastectomy lymphoedema syndrome
0.001 0.875 0.124
I44.3 Other and unspecified atrioventricular block
0.000 0.877 0.123
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.877 0.123
J91 Pleural effusion in conditions classified elsewhere
0.000 0.879 0.121
I89.1 Lymphangitis
0.000 0.880 0.120
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.882 0.118
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.001 0.883 0.117
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.001 0.883 0.117
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.001 0.883 0.117
I98.0 Cardiovascular syphilis
0.001 0.883 0.117
I97.9 Postprocedural disorder of circulatory system, unspecified
0.001 0.883 0.116
I97.0 Postcardiotomy syndrome
0.001 0.883 0.116
J93.0 Spontaneous tension pneumothorax
0.000 0.887 0.113
I73.0 Raynaud's syndrome
0.002 0.889 0.109
J92.0 Pleural plaque with presence of asbestos
0.000 0.892 0.108
I82.8 Embolism and thrombosis of other specified veins
0.000 0.892 0.108
I87.1 Compression of vein
0.000 0.893 0.107
J94.9 Pleural condition, unspecified
0.000 0.896 0.104
J94.1 Fibrothorax
0.000 0.896 0.104
J94.0 Chylous effusion
0.000 0.896 0.104
J94.2 Haemothorax
0.000 0.899 0.101
I97.1 Other functional disturbances following cardiac surgery
0.001 0.900 0.100
I87.9 Disorder of vein, unspecified
0.000 0.902 0.098
I87.0 Postphlebitic syndrome
0.000 0.902 0.098
I85.0 Oesophageal varices with bleeding
0.000 0.904 0.096
I85.9 Oesophageal varices without bleeding
0.000 0.910 0.090
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.002 0.911 0.088
I44.2 Atrioventricular block, complete
0.000 0.912 0.088
I44.0 Atrioventricular block, first degree
0.000 0.921 0.079
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.927 0.072
I95 Hypotension
0.000 0.930 0.070
E70-E90 Metabolic disorders
0.000 0.932 0.068
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.935 0.064
I87.2 Venous insufficiency (chronic) (peripheral)
0.001 0.936 0.063
I87.8 Other specified disorders of veins
0.001 0.938 0.061
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.941 0.059
E88 Other metabolic disorders
0.000 0.943 0.057
E89.0 Postprocedural hypothyroidism
0.000 0.949 0.051
I95.0 Idiopathic hypotension
0.000 0.949 0.050
E84 Cystic fibrosis
0.000 0.951 0.049
E79 Disorders of purine and pyrimidine metabolism
0.000 0.951 0.049
E77 Disorders of glycoprotein metabolism
0.000 0.951 0.049
E76 Disorders of glycosaminoglycan metabolism
0.000 0.951 0.049
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.951 0.049
E72 Other disorders of amino-acid metabolism
0.000 0.951 0.049
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.951 0.049
E70 Disorders of aromatic amino-acid metabolism
0.000 0.951 0.049
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.951 0.049
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.951 0.049
E74 Other disorders of carbohydrate metabolism
0.000 0.951 0.049
E73 Lactose intolerance
0.000 0.953 0.047
E85 Amyloidosis
0.000 0.955 0.045
E89.3 Postprocedural hypopituitarism
0.000 0.956 0.043
I95.1 Orthostatic hypotension
0.000 0.957 0.043
I95.2 Hypotension due to drugs
0.000 0.957 0.043
E89.2 Postprocedural hypoparathyroidism
0.000 0.957 0.043
I95.8 Other hypotension
0.000 0.957 0.042
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.958 0.042
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.958 0.042
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.958 0.042
E89.5 Postprocedural testicular hypofunction
0.000 0.958 0.042
E89.4 Postprocedural ovarian failure
0.000 0.958 0.042
E89.1 Postprocedural hypoinsulinaemia
0.000 0.958 0.042
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.958 0.042
E88.9 Metabolic disorder, unspecified
0.000 0.959 0.041
E88.8 Other specified metabolic disorders
0.000 0.959 0.041
E88.3 Tumour lysis syndrome
0.000 0.959 0.041
E88.2 Lipomatosis, not elsewhere classified
0.000 0.959 0.041
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.959 0.041
Z95.1 Presence of aortocoronary bypass graft
0.000 0.960 0.040
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.965 0.035
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.965 0.035
E70.3 Albinism
0.000 0.965 0.035
E70.2 Disorders of tyrosine metabolism
0.000 0.965 0.035
E70.1 Other hyperphenylalaninaemias
0.000 0.965 0.035
E70.0 Classical phenylketonuria
0.000 0.965 0.035
E71.3 Disorders of fatty-acid metabolism
0.000 0.965 0.035
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.965 0.035
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.965 0.035
E71.0 Maple-syrup-urine disease
0.000 0.965 0.035
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.965 0.035
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.965 0.035
E72.5 Disorders of glycine metabolism
0.000 0.965 0.035
E72.4 Disorders of ornithine metabolism
0.000 0.965 0.035
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.965 0.035
E72.2 Disorders of urea cycle metabolism
0.000 0.965 0.035
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.965 0.035
E72.0 Disorders of amino-acid transport
0.000 0.965 0.035
E75.6 Lipid storage disorder, unspecified
0.000 0.965 0.035
E75.5 Other lipid storage disorders
0.000 0.965 0.035
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.965 0.035
E75.3 Sphingolipidosis, unspecified
0.000 0.965 0.035
E75.2 Other sphingolipidosis
0.000 0.965 0.035
E75.1 Other gangliosidosis
0.000 0.965 0.035
E75.0 GM2 gangliosidosis
0.000 0.965 0.035
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.965 0.035
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.965 0.035
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.965 0.035
E76.2 Other mucopolysaccharidoses
0.000 0.965 0.035
E76.1 Mucopolysaccharidosis, type II
0.000 0.965 0.035
E76.0 Mucopolysaccharidosis, type I
0.000 0.965 0.035
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.965 0.035
E77.8 Other disorders of glycoprotein metabolism
0.000 0.965 0.035
E77.1 Defects in glycoprotein degradation
0.000 0.965 0.035
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.965 0.035
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.965 0.035
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.965 0.035
E79.1 Lesch-Nyhan syndrome
0.000 0.965 0.035
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.965 0.035
E84.9 Cystic fibrosis, unspecified
0.000 0.965 0.035
E84.8 Cystic fibrosis with other manifestations
0.000 0.965 0.035
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.965 0.035
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.965 0.035
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.965 0.035

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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