TreeWAS – Variant ID: rs636523

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.000	1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.001	0.999
E78.1 Pure hyperglyceridaemia	0.000	0.157	0.843
E78.6 Lipoprotein deficiency	0.000	0.271	0.728
E78.3 Hyperchylomicronaemia	0.000	0.283	0.716
E78.8 Other disorders of lipoprotein metabolism	0.000	0.305	0.695
E78.4 Other hyperlipidaemia	0.000	0.330	0.670
E78.2 Mixed hyperlipidaemia	0.000	0.495	0.505
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.552	0.448
E89.0 Postprocedural hypothyroidism	0.000	0.599	0.401
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.614	0.386
E70-E90 Metabolic disorders	0.000	0.616	0.384
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.693	0.307
E79 Disorders of purine and pyrimidine metabolism	0.000	0.702	0.297
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.708	0.292
E89.3 Postprocedural hypopituitarism	0.000	0.715	0.285
E84 Cystic fibrosis	0.000	0.718	0.282
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.723	0.277
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.723	0.277
E89.5 Postprocedural testicular hypofunction	0.000	0.723	0.277
E77 Disorders of glycoprotein metabolism	0.000	0.724	0.276
E76 Disorders of glycosaminoglycan metabolism	0.000	0.724	0.276
E72 Other disorders of amino-acid metabolism	0.000	0.724	0.276
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.724	0.276
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.724	0.276
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.734	0.266
E85 Amyloidosis	0.000	0.746	0.254
E89.1 Postprocedural hypoinsulinaemia	0.000	0.750	0.250
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.752	0.248
E87.6 Hypokalaemia	0.000	0.754	0.246
E80.4 Gilbert's syndrome	0.000	0.758	0.242
E80.1 Porphyria cutanea tarda	0.000	0.760	0.240
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.765	0.235
E89.2 Postprocedural hypoparathyroidism	0.000	0.765	0.234
E73 Lactose intolerance	0.000	0.767	0.233
E75.5 Other lipid storage disorders	0.000	0.773	0.226
E70 Disorders of aromatic amino-acid metabolism	0.000	0.776	0.224
E80.2 Other porphyria	0.000	0.779	0.221
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.780	0.220
E80.5 Crigler-Najjar syndrome	0.000	0.780	0.220
E80.3 Defects of catalase and peroxydase	0.000	0.780	0.220
E80.0 Hereditary erythropoietic porphyria	0.000	0.780	0.220
E89.4 Postprocedural ovarian failure	0.000	0.781	0.219
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.784	0.216
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.786	0.213
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.786	0.213
E79.1 Lesch-Nyhan syndrome	0.000	0.786	0.213
E75.6 Lipid storage disorder, unspecified	0.000	0.790	0.210
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.790	0.210
E75.3 Sphingolipidosis, unspecified	0.000	0.790	0.210
E75.2 Other sphingolipidosis	0.000	0.790	0.210
E75.1 Other gangliosidosis	0.000	0.790	0.210
E75.0 GM2 gangliosidosis	0.000	0.790	0.210
E80.6 Other disorders of bilirubin metabolism	0.000	0.791	0.209
E84.9 Cystic fibrosis, unspecified	0.000	0.791	0.208
E87.5 Hyperkalaemia	0.000	0.794	0.206
E84.8 Cystic fibrosis with other manifestations	0.000	0.798	0.202
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.798	0.202
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.798	0.202
E74 Other disorders of carbohydrate metabolism	0.000	0.801	0.199
E71.3 Disorders of fatty-acid metabolism	0.000	0.802	0.198
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.802	0.198
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.802	0.198
E71.0 Maple-syrup-urine disease	0.000	0.802	0.198
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.802	0.198
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.802	0.198
E72.5 Disorders of glycine metabolism	0.000	0.802	0.198
E72.4 Disorders of ornithine metabolism	0.000	0.802	0.198
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.802	0.198
E72.2 Disorders of urea cycle metabolism	0.000	0.802	0.198
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.802	0.198
E72.0 Disorders of amino-acid transport	0.000	0.802	0.198
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.802	0.198
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.802	0.198
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.802	0.198
E76.2 Other mucopolysaccharidoses	0.000	0.802	0.198
E76.1 Mucopolysaccharidosis, type II	0.000	0.802	0.198
E76.0 Mucopolysaccharidosis, type I	0.000	0.802	0.198
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.802	0.198
E77.8 Other disorders of glycoprotein metabolism	0.000	0.802	0.198
E77.1 Defects in glycoprotein degradation	0.000	0.802	0.198
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.802	0.198
E85.3 Secondary systemic amyloidosis	0.000	0.807	0.192
E85.8 Other amyloidosis	0.000	0.818	0.182
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.818	0.182
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.818	0.182
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.818	0.182
E87.4 Mixed disorder of acid-base balance	0.000	0.822	0.178
E85.9 Amyloidosis, unspecified	0.000	0.827	0.173
E73.8 Other lactose intolerance	0.000	0.832	0.167
E73.1 Secondary lactase deficiency	0.000	0.832	0.167
E73.0 Congenital lactase deficiency	0.000	0.832	0.167
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.839	0.160
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.839	0.160
E70.2 Disorders of tyrosine metabolism	0.000	0.839	0.160
E70.1 Other hyperphenylalaninaemias	0.000	0.839	0.160
E70.0 Classical phenylketonuria	0.000	0.839	0.160
E85.4 Organ-limited amyloidosis	0.000	0.842	0.158
E88 Other metabolic disorders	0.000	0.854	0.145
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.857	0.143
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.857	0.143
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.857	0.143
E74.2 Disorders of galactose metabolism	0.000	0.857	0.143
E74.1 Disorders of fructose metabolism	0.000	0.857	0.143
E73.9 Lactose intolerance, unspecified	0.000	0.875	0.125
E87.0 Hyperosmolality and hypernatraemia	0.000	0.884	0.116
E74.0 Glycogen storage disease	0.001	0.887	0.113
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.887	0.112
E70.3 Albinism	0.001	0.891	0.108
E87.7 Fluid overload	0.000	0.894	0.106
E87.3 Alkalosis	0.000	0.894	0.105
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.895	0.104
E88.3 Tumour lysis syndrome	0.000	0.896	0.104
E88.8 Other specified metabolic disorders	0.000	0.901	0.099
E88.9 Metabolic disorder, unspecified	0.000	0.902	0.097
E83 Disorders of mineral metabolism	0.000	0.909	0.091
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.919	0.081
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.934	0.066
E83.8 Other disorders of mineral metabolism	0.000	0.934	0.066
E83.2 Disorders of zinc metabolism	0.000	0.934	0.066
E83.0 Disorders of copper metabolism	0.000	0.934	0.066
E83.5 Disorders of calcium metabolism	0.000	0.935	0.065
E88.2 Lipomatosis, not elsewhere classified	0.001	0.936	0.063
E83.4 Disorders of magnesium metabolism	0.000	0.938	0.062
E10.3 With ophthalmic complications	0.000	0.941	0.059
E10 Insulin-dependent diabetes mellitus	0.000	0.945	0.055
E10.6 With other specified complications	0.000	0.949	0.051
E10.0 With coma	0.000	0.951	0.049
E10.9 Without complications	0.000	0.953	0.047
E10.4 With neurological complications	0.000	0.955	0.045
E10.7 With multiple complications	0.000	0.960	0.040
E10.1 With ketoacidosis	0.000	0.960	0.040
E10-E14 Diabetes mellitus	0.000	0.961	0.039
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.961	0.039
E10.5 With peripheral circulatory complications	0.000	0.963	0.037
G45.9 Transient cerebral ischaemic attack, unspecified	0.034	0.966	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.966	0.034
E10.8 With unspecified complications	0.000	0.970	0.030
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.971	0.029
E10.2 With renal complications	0.000	0.971	0.029
E12 Malnutrition-related diabetes mellitus	0.000	0.972	0.028
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.972	0.028
E13 Other specified diabetes mellitus	0.000	0.973	0.027
E86 Volume depletion	0.000	0.975	0.025
E40-E46 Malnutrition	0.000	0.975	0.025
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.025	0.975	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.024	0.976	0.000
E87.2 Acidosis	0.000	0.976	0.024
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.023	0.977	0.000
M35.0 Sicca syndrome [Sjogren]	0.023	0.977	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.978	0.022
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.979	0.021
E15 Nondiabetic hypoglycaemic coma	0.000	0.979	0.021
E12.9 Without complications	0.000	0.979	0.020
E12.8 With unspecified complications	0.000	0.979	0.020
E12.7 With multiple complications	0.000	0.979	0.020
E12.6 With other specified complications	0.000	0.979	0.020
E12.5 With peripheral circulatory complications	0.000	0.979	0.020
E12.4 With neurological complications	0.000	0.979	0.020
E12.3 With ophthalmic complications	0.000	0.979	0.020
E12.2 With renal complications	0.000	0.979	0.020
E12.1 With ketoacidosis	0.000	0.979	0.020
E12.0 With coma	0.000	0.979	0.020
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.020	0.980	0.000
E13.3 With ophthalmic complications	0.000	0.980	0.019
E13.8 With unspecified complications	0.000	0.981	0.019
E13.7 With multiple complications	0.000	0.981	0.019
E13.6 With other specified complications	0.000	0.981	0.019
E13.5 With peripheral circulatory complications	0.000	0.981	0.019
E13.4 With neurological complications	0.000	0.981	0.019
E13.2 With renal complications	0.000	0.981	0.019
E13.1 With ketoacidosis	0.000	0.981	0.019
E13.0 With coma	0.000	0.981	0.019
M80 Osteoporosis with pathological fracture	0.019	0.981	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.981	0.019
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.019	0.981	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.018	0.982	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.982	0.018
E45 Retarded development following protein-energy malnutrition	0.000	0.982	0.018
E43 Unspecified severe protein-energy malnutrition	0.000	0.982	0.018
E42 Marasmic kwashiorkor	0.000	0.982	0.018
E41 Nutritional marasmus	0.000	0.982	0.018
E40 Kwashiorkor	0.000	0.982	0.018
E13.9 Without complications	0.000	0.982	0.018
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.018	0.982	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.018	0.982	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.018	0.982	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.018	0.982	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.018	0.982	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.018	0.982	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.018	0.982	0.000
E14 Unspecified diabetes mellitus	0.000	0.982	0.018
G45 Transient cerebral ischaemic attacks and related syndromes	0.016	0.984	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.984	0.016
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.984	0.016
E16.4 Abnormal secretion of gastrin	0.000	0.984	0.016
E16.3 Increased secretion of glucagon	0.000	0.984	0.016
E16.1 Other hypoglycaemia	0.000	0.985	0.015
E14.3 With ophthalmic complications	0.000	0.985	0.015
E46 Unspecified protein-energy malnutrition	0.000	0.985	0.015
G43.9 Migraine, unspecified	0.015	0.985	0.000
G56.2 Lesion of ulnar nerve	0.015	0.985	0.000
G56.8 Other mononeuropathies of upper limb	0.014	0.986	0.000
E65 Localised adiposity	0.000	0.986	0.014
M80.5 Idiopathic osteoporosis with pathological fracture	0.014	0.986	0.000
E14.2 Withrenal complications	0.000	0.986	0.014
M80.4 Drug-induced osteoporosis with pathological fracture	0.013	0.986	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.013	0.986	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.013	0.986	0.000
E67 Other hyperalimentation	0.000	0.986	0.013
E68 Sequelae of hyperalimentation	0.000	0.986	0.013
G43 Migraine	0.014	0.986	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.013	0.987	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.013	0.987	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.013	0.987	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.013	0.987	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.013	0.987	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.013	0.987	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.013	0.987	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.013	0.987	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.013	0.987	0.000
G56.3 Lesion of radial nerve	0.013	0.987	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.987	0.013
E44.0 Moderate protein-energy malnutrition	0.000	0.987	0.013
M80.8 Other osteoporosis with pathological fracture	0.013	0.987	0.000
E14.6 With other specified complications	0.000	0.987	0.013
G56 Mononeuropathies of upper limb	0.013	0.987	0.000
E14.7 With multiple complications	0.000	0.987	0.013
E14.0 With coma	0.000	0.987	0.013
G45.0 Vertebro-basilar artery syndrome	0.012	0.988	0.000
G40.9 Epilepsy, unspecified	0.012	0.988	0.000
E14.5 With peripheral circulatory complications	0.000	0.988	0.012
G40-G47 Episodic and paroxysmal disorders	0.012	0.988	0.000
G43.8 Other migraine	0.012	0.988	0.000
E14.8 With unspecified complications	0.000	0.988	0.012
E14.4 With neurological complications	0.000	0.988	0.012
E83.1 Disorders of iron metabolism	0.000	0.988	0.012
G45.2 Multiple and bilateral precerebral artery syndromes	0.012	0.988	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.012	0.988	0.000
C44.5 Skin of trunk	0.012	0.988	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.012	0.988	0.000
R21 Rash and other nonspecific skin eruption	0.000	0.988	0.012
Q60.0 Renal agenesis, unilateral	0.011	0.989	0.000
G40 Epilepsy	0.011	0.989	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.011	0.989	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.010	0.990	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.010	0.990	0.000
G56.1 Other lesions of median nerve	0.010	0.990	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.010	0.990	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.010	0.990	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.010	0.990	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.010	0.990	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.010	0.990	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.010	0.990	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.010	0.990	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.010	0.990	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.010	0.990	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.010	0.990	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.010	0.990	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.010	0.990	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
E67.8 Other specified hyperalimentation	0.000	0.990	0.010
E67.3 Hypervitaminosis D	0.000	0.990	0.010
E67.2 Megavitamin-B6 syndrome	0.000	0.990	0.010
E67.1 Hypercarotenaemia	0.000	0.990	0.010
E67.0 Hypervitaminosis A	0.000	0.990	0.010
E50-E64 Other nutritional deficiencies	0.000	0.990	0.010
G43.2 Status migrainosus	0.010	0.990	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.010	0.990	0.000
G45.4 Transient global amnesia	0.010	0.990	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
G43.0 Migraine without aura [common migraine]	0.009	0.990	0.000
E14.1 With ketoacidosis	0.000	0.991	0.009
G43.3 Complicated migraine	0.009	0.991	0.000
E04.2 Non-toxic multinodular goitre	0.009	0.991	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.009	0.991	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.009	0.991	0.000
G44 Other headache syndromes	0.009	0.991	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.009	0.991	0.000
G45.3 Amaurosis fugax	0.008	0.991	0.000
G56.4 Causalgia	0.008	0.991	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.008	0.992	0.000
S82.20 Fracture of shaft of tibia (closed)	0.008	0.992	0.000
G43.1 Migraine with aura [classical migraine]	0.008	0.992	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.008	0.992	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.008	0.992	0.000
G44.0 Cluster headache syndrome	0.008	0.992	0.000
E56 Other vitamin deficiencies	0.000	0.992	0.008
Q60 Renal agenesis and other reduction defects of kidney	0.008	0.992	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.008	0.992	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.008	0.992	0.000
M07.3 Other psoriatic arthropathies	0.008	0.992	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.007	0.992	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.007	0.992	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.007	0.992	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.007	0.992	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.992	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.007	0.992	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.007	0.992	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.007	0.992	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.007	0.992	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.993	0.007
E50 Vitamin A deficiency	0.000	0.993	0.007
E60 Dietary zinc deficiency	0.000	0.993	0.007
E59 Dietary selenium deficiency	0.000	0.993	0.007
E54 Ascorbic acid deficiency	0.000	0.993	0.007
E52 Niacin deficiency [pellagra]	0.000	0.993	0.007
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.007	0.993	0.000
G40.8 Other epilepsy	0.007	0.993	0.000
G41 Status epilepticus	0.007	0.993	0.000
E63 Other nutritional deficiencies	0.000	0.993	0.007
K31.1 Adult hypertrophic pyloric stenosis	0.007	0.993	0.000
G44.1 Vascular headache, not elsewhere classified	0.007	0.993	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.007	0.993	0.000
E58 Dietary calcium deficiency	0.000	0.993	0.007
G44.4 Drug-induced headache, not elsewhere classified	0.007	0.993	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.993	0.007
G44.8 Other specified headache syndromes	0.007	0.993	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.006	0.993	0.000
G46.6 Pure sensory lacunar syndrome	0.006	0.993	0.000
G46.5 Pure motor lacunar syndrome	0.006	0.993	0.000
G46.3 Brain stem stroke syndrome	0.006	0.993	0.000
G46.2 Posterior cerebral artery syndrome	0.006	0.993	0.000
G46.1 Anterior cerebral artery syndrome	0.006	0.993	0.000
G46.0 Middle cerebral artery syndrome	0.006	0.993	0.000
G46.4 Cerebellar stroke syndrome	0.006	0.993	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.993	0.007
E51 Thiamine deficiency	0.000	0.993	0.006
H90.5 Sensorineural hearing loss, unspecified	0.000	0.994	0.006
H90.0 Conductive hearing loss, bilateral	0.000	0.994	0.006
H36.0 Diabetic retinopathy	0.000	0.994	0.006
H90 Conductive and sensorineural hearing loss	0.000	0.994	0.006
M80-M85 Disorders of bone density and structure	0.006	0.994	0.000
G44.3 Chronic posttraumatic headache	0.006	0.994	0.000
G46.7 Other lacunar syndromes	0.006	0.994	0.000
E56.1 Deficiency of vitamin K	0.000	0.994	0.006
M07.34 Other psoriatic arthropathies (Hand)	0.006	0.994	0.000
Q60.2 Renal agenesis, unspecified	0.006	0.994	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.006	0.994	0.000
G40.5 Special epileptic syndromes	0.006	0.994	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.006	0.994	0.000
G41.8 Other status epilepticus	0.006	0.994	0.000
E56.9 Vitamin deficiency, unspecified	0.000	0.994	0.006
E56.8 Deficiency of other vitamins	0.000	0.994	0.006
E56.0 Deficiency of vitamin E	0.000	0.994	0.006
Q60.6 Potter's syndrome	0.006	0.994	0.000
Q60.5 Renal hypoplasia, unspecified	0.006	0.994	0.000
Q60.4 Renal hypoplasia, bilateral	0.006	0.994	0.000
Q60.3 Renal hypoplasia, unilateral	0.006	0.994	0.000
Q60.1 Renal agenesis, bilateral	0.006	0.994	0.000
M84.06 Malunion of fracture (Lower leg)	0.006	0.994	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.994	0.006
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.994	0.006
M07.33 Other psoriatic arthropathies (Forearm)	0.006	0.994	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.006	0.994	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.994	0.006
M07.38 Other psoriatic arthropathies (Other)	0.006	0.994	0.000
M84.0 Malunion of fracture	0.006	0.994	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.994	0.005
E50.8 Other manifestations of vitamin A deficiency	0.000	0.994	0.005
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.994	0.005
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.994	0.005
E50.5 Vitamin A deficiency with night blindness	0.000	0.994	0.005
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.994	0.005
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.994	0.005
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.994	0.005
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.994	0.005
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.994	0.005
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.994	0.005
E64.8 Sequelae of other nutritional deficiencies	0.000	0.994	0.005
E64.3 Sequelae of rickets	0.000	0.994	0.005
E64.2 Sequelae of vitamin C deficiency	0.000	0.994	0.005
E64.1 Sequelae of vitamin A deficiency	0.000	0.994	0.005
E64.0 Sequelae of protein-energy malnutrition	0.000	0.994	0.005
Q23 Congenital malformations of aortic and mitral valves	0.006	0.994	0.000
M06.3 Rheumatoid nodule	0.006	0.994	0.000
Z87.0 Personal history of diseases of the respiratory system	0.000	0.994	0.006
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
O03.4 Incomplete, without complication	0.006	0.994	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.005	0.994	0.000
M06.34 Rheumatoid nodule (Hand)	0.005	0.994	0.000
G41.1 Petit mal status epilepticus	0.005	0.994	0.000
E61 Deficiency of other nutrient elements	0.000	0.995	0.005
E55 Vitamin D deficiency	0.000	0.995	0.005
H90.3 Sensorineural hearing loss, bilateral	0.000	0.995	0.005
Q23.1 Congenital insufficiency of aortic valve	0.005	0.995	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.005	0.995	0.000
E63.8 Other specified nutritional deficiencies	0.000	0.995	0.005
E63.1 Imbalance of constituents of food intake	0.000	0.995	0.005
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.995	0.005
G41.0 Grand mal status epilepticus	0.005	0.995	0.000
G41.2 Complex partial status epilepticus	0.005	0.995	0.000
M84 Disorders of continuity of bone	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
E63.9 Nutritional deficiency, unspecified	0.000	0.995	0.005
E53 Deficiency of other B group vitamins	0.000	0.995	0.005
M06 Other rheumatoid arthritis	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
M07 Psoriatic and enteropathic arthropathies	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.995	0.000
E51.9 Thiamine deficiency, unspecified	0.000	0.995	0.005
E51.8 Other manifestations of thiamine deficiency	0.000	0.995	0.005
E51.1 Beriberi	0.000	0.995	0.005
S22.40 Multiple fractures of ribs (closed)	0.000	0.995	0.005
M06.0 Seronegative rheumatoid arthritis	0.005	0.995	0.000
M84.2 Delayed union of fracture	0.005	0.995	0.000
M84.03 Malunion of fracture (Forearm)	0.005	0.995	0.000
M83 Adult osteomalacia	0.005	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
M84.01 Malunion of fracture (Shoulder region)	0.005	0.995	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.995	0.005
Q26 Congenital malformations of great veins	0.005	0.995	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.005	0.995	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.005	0.995	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.995	0.005
M84.26 Delayed union of fracture (Lower leg)	0.005	0.995	0.000
M84.08 Malunion of fracture (Other)	0.005	0.995	0.000
Q23.0 Congenital stenosis of aortic valve	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
M85 Other disorders of bone density and structure	0.005	0.995	0.000
Q50-Q56 Congenital malformations of genital organs	0.005	0.995	0.000
Q25.3 Stenosis of aorta	0.004	0.995	0.000
Q25.0 Patent ductus arteriosus	0.004	0.995	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.005	0.995	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.004	0.995	0.000
M84.04 Malunion of fracture (Hand)	0.004	0.995	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.995	0.004
E00-E07 Disorders of thyroid gland	0.001	0.995	0.004
M06.9 Rheumatoid arthritis, unspecified	0.005	0.995	0.000
Q22.5 Ebstein's anomaly	0.004	0.995	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.004	0.996	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.004	0.996	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.004	0.996	0.000
Q53 Undescended testicle	0.004	0.996	0.000
M85.2 Hyperostosis of skull	0.004	0.996	0.000
M84.09 Malunion of fracture (Site unspecified)	0.004	0.996	0.000
M84.00 Malunion of fracture (Multiple sites)	0.004	0.996	0.000
Z75 Problems related to medical facilities and other health care	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.004	0.996	0.000
M06.38 Rheumatoid nodule (Other)	0.004	0.996	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.004	0.996	0.000
M06.33 Rheumatoid nodule (Forearm)	0.004	0.996	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.996	0.000
Q23.2 Congenital mitral stenosis	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.004	0.996	0.000
M82 Osteoporosis in diseases classified elsewhere	0.004	0.996	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.996	0.004
E61.8 Deficiency of other specified nutrient elements	0.000	0.996	0.004
E61.7 Deficiency of multiple nutrient elements	0.000	0.996	0.004
E61.6 Vanadium deficiency	0.000	0.996	0.004
E61.5 Molybdenum deficiency	0.000	0.996	0.004
E61.4 Chromium deficiency	0.000	0.996	0.004
E61.3 Manganese deficiency	0.000	0.996	0.004
E61.0 Copper deficiency	0.000	0.996	0.004
Z75.3 Unavailability and inaccessibility of health-care facilities	0.004	0.996	0.000
E55.0 Rickets, active	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations