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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs641153
log Bayes Factor = 26.8078
Chromosome 6   position 31,914,180  (GRCh37) Explore rs641153 on Ensembl!
Variant rs641153 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.009 0.991
E11 Non-insulin-dependent diabetes mellitus
0.000 0.021 0.979
E05.9 Thyrotoxicosis, unspecified
0.000 0.033 0.967
E65-E68 Obesity and other hyperalimentation
0.000 0.041 0.959
E10.1 With ketoacidosis
0.000 0.049 0.951
E11.3 With ophthalmic complications
0.000 0.050 0.950
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.053 0.947
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.060 0.940
E66 Obesity
0.000 0.072 0.928
E66.8 Other obesity
0.000 0.076 0.924
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.117 0.883
E11.9 Without complications
0.000 0.124 0.876
E10.5 With peripheral circulatory complications
0.000 0.135 0.865
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.136 0.864
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.151 0.849
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.161 0.839
E11.5 With peripheral circulatory complications
0.000 0.190 0.810
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.193 0.807
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.200 0.800
E06 Thyroiditis
0.000 0.211 0.789
M06 Other rheumatoid arthritis
0.001 0.218 0.782
E10.4 With neurological complications
0.000 0.224 0.776
E10.2 With renal complications
0.000 0.234 0.766
E11.2 With renal complications
0.000 0.241 0.759
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.264 0.736
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E65 Localised adiposity
0.000 0.290 0.710
M06.0 Seronegative rheumatoid arthritis
0.000 0.297 0.703
E11.7 With multiple complications
0.000 0.298 0.702
E13 Other specified diabetes mellitus
0.000 0.300 0.700
E11.0 With coma
0.000 0.302 0.698
E67 Other hyperalimentation
0.000 0.312 0.688
E68 Sequelae of hyperalimentation
0.000 0.312 0.688
E11.6 With other specified complications
0.000 0.321 0.679
E50-E64 Other nutritional deficiencies
0.000 0.322 0.678
E10.8 With unspecified complications
0.000 0.334 0.666
E66.1 Drug-induced obesity
0.000 0.335 0.665
E06.3 Autoimmune thyroiditis
0.000 0.355 0.645
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.355 0.645
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.363 0.637
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.370 0.629
E66.0 Obesity due to excess calories
0.000 0.375 0.625
E11.8 With unspecified complications
0.000 0.381 0.619
E14 Unspecified diabetes mellitus
0.000 0.385 0.615
E40-E46 Malnutrition
0.000 0.387 0.613
E11.1 With ketoacidosis
0.000 0.388 0.612
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.395 0.605
M06.3 Rheumatoid nodule
0.001 0.402 0.597
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.411 0.589
E11.4 With neurological complications
0.000 0.429 0.571
E06.5 Other chronic thyroiditis
0.000 0.434 0.566
E06.4 Drug-induced thyroiditis
0.000 0.434 0.566
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.434 0.566
E06.1 Subacute thyroiditis
0.000 0.434 0.566
E06.0 Acute thyroiditis
0.000 0.434 0.566
M06.8 Other specified rheumatoid arthritis
0.001 0.439 0.560
M06.2 Rheumatoid bursitis
0.001 0.439 0.560
M06.1 Adult-onset Still's disease
0.001 0.439 0.560
E06.9 Thyroiditis, unspecified
0.000 0.446 0.554
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.496 0.504
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.496 0.504
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.496 0.504
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.496 0.504
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.496 0.504
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.496 0.504
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.496 0.504
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.496 0.504
E20-E35 Disorders of other endocrine glands
0.000 0.497 0.503
E13.8 With unspecified complications
0.000 0.498 0.502
E13.7 With multiple complications
0.000 0.498 0.502
E13.6 With other specified complications
0.000 0.498 0.502
E13.5 With peripheral circulatory complications
0.000 0.498 0.502
E13.4 With neurological complications
0.000 0.498 0.502
E13.3 With ophthalmic complications
0.000 0.498 0.502
E13.2 With renal complications
0.000 0.498 0.502
E13.1 With ketoacidosis
0.000 0.498 0.502
E13.0 With coma
0.000 0.498 0.502
M06.4 Inflammatory polyarthropathy
0.001 0.498 0.501
E67.8 Other specified hyperalimentation
0.000 0.507 0.493
E67.3 Hypervitaminosis D
0.000 0.507 0.493
E67.2 Megavitamin-B6 syndrome
0.000 0.507 0.493
E67.1 Hypercarotenaemia
0.000 0.507 0.493
E67.0 Hypervitaminosis A
0.000 0.507 0.493
E03.8 Other specified hypothyroidism
0.001 0.513 0.486
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.514 0.486
E63 Other nutritional deficiencies
0.000 0.514 0.486
E56 Other vitamin deficiencies
0.000 0.514 0.486
E51 Thiamine deficiency
0.000 0.514 0.486
E50 Vitamin A deficiency
0.000 0.514 0.486
E60 Dietary zinc deficiency
0.000 0.514 0.486
E59 Dietary selenium deficiency
0.000 0.514 0.486
E58 Dietary calcium deficiency
0.000 0.514 0.486
E54 Ascorbic acid deficiency
0.000 0.514 0.486
E52 Niacin deficiency [pellagra]
0.000 0.514 0.486
E13.9 Without complications
0.000 0.514 0.485
E55 Vitamin D deficiency
0.000 0.519 0.481
E61 Deficiency of other nutrient elements
0.000 0.525 0.475
E07 Other disorders of thyroid
0.000 0.529 0.471
E27 Other disorders of adrenal gland
0.000 0.532 0.468
E53 Deficiency of other B group vitamins
0.000 0.533 0.467
E14.3 With ophthalmic complications
0.000 0.533 0.467
M06.34 Rheumatoid nodule (Hand)
0.000 0.534 0.465
E15 Nondiabetic hypoglycaemic coma
0.000 0.537 0.463
E14.8 With unspecified complications
0.000 0.559 0.441
E14.7 With multiple complications
0.000 0.559 0.441
E14.6 With other specified complications
0.000 0.559 0.441
E14.5 With peripheral circulatory complications
0.000 0.559 0.441
E14.4 With neurological complications
0.000 0.559 0.441
E14.1 With ketoacidosis
0.000 0.559 0.441
E14.0 With coma
0.000 0.559 0.441
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.560 0.440
E45 Retarded development following protein-energy malnutrition
0.000 0.560 0.440
E43 Unspecified severe protein-energy malnutrition
0.000 0.560 0.440
E42 Marasmic kwashiorkor
0.000 0.560 0.440
E41 Nutritional marasmus
0.000 0.560 0.440
E40 Kwashiorkor
0.000 0.560 0.440
M06.39 Rheumatoid nodule (Site unspecified)
0.001 0.571 0.428
M06.38 Rheumatoid nodule (Other)
0.001 0.571 0.428
M06.37 Rheumatoid nodule (Ankle and foot)
0.001 0.571 0.428
M06.36 Rheumatoid nodule (Lower leg)
0.001 0.571 0.428
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.001 0.571 0.428
M06.33 Rheumatoid nodule (Forearm)
0.001 0.571 0.428
M06.32 Rheumatoid nodule (Upper arm)
0.001 0.571 0.428
M06.31 Rheumatoid nodule (Shoulder region)
0.001 0.571 0.428
M06.30 Rheumatoid nodule (Multiple sites)
0.001 0.571 0.428
E27.1 Primary adrenocortical insufficiency
0.000 0.582 0.418
M06.19 Adult-onset Still's disease (Site unspecified)
0.001 0.598 0.402
M06.18 Adult-onset Still's disease (Other)
0.001 0.598 0.402
M06.17 Adult-onset Still's disease (Ankle and foot)
0.001 0.598 0.402
M06.16 Adult-onset Still's disease (Lower leg)
0.001 0.598 0.402
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.001 0.598 0.402
M06.14 Adult-onset Still's disease (Hand)
0.001 0.598 0.402
M06.13 Adult-onset Still's disease (Forearm)
0.001 0.598 0.402
M06.12 Adult-onset Still's disease (Upper arm)
0.001 0.598 0.402
M06.11 Adult-onset Still's disease (Shoulder region)
0.001 0.598 0.402
M06.10 Adult-onset Still's disease (Multiple sites)
0.001 0.598 0.402
M06.29 Rheumatoid bursitis (Site unspecified)
0.001 0.598 0.402
M06.28 Rheumatoid bursitis (Other)
0.001 0.598 0.402
M06.27 Rheumatoid bursitis (Ankle and foot)
0.001 0.598 0.402
M06.26 Rheumatoid bursitis (Lower leg)
0.001 0.598 0.402
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.001 0.598 0.402
M06.24 Rheumatoid bursitis (Hand)
0.001 0.598 0.402
M06.23 Rheumatoid bursitis (Forearm)
0.001 0.598 0.402
M06.22 Rheumatoid bursitis (Upper arm)
0.001 0.598 0.402
M06.21 Rheumatoid bursitis (Shoulder region)
0.001 0.598 0.402
M06.20 Rheumatoid bursitis (Multiple sites)
0.001 0.598 0.402
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.001 0.598 0.402
M06.88 Other specified rheumatoid arthritis (Other)
0.001 0.598 0.402
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.001 0.598 0.402
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.001 0.598 0.402
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.001 0.598 0.402
M06.84 Other specified rheumatoid arthritis (Hand)
0.001 0.598 0.402
M06.83 Other specified rheumatoid arthritis (Forearm)
0.001 0.598 0.402
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.001 0.598 0.402
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.001 0.598 0.402
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.001 0.598 0.402
E20 Hypoparathyroidism
0.000 0.605 0.394
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.605 0.394
E27.8 Other specified disorders of adrenal gland
0.000 0.606 0.393
E16 Other disorders of pancreatic internal secretion
0.000 0.609 0.391
E14.9 Without complications
0.000 0.610 0.390
E04 Other non-toxic goitre
0.000 0.611 0.389
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.619 0.381
M05-M14 Inflammatory polyarthropathies
0.006 0.630 0.364
E14.2 Withrenal complications
0.000 0.635 0.365
E27.2 Addisonian crisis
0.000 0.636 0.363
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.639 0.361
E32 Diseases of thymus
0.000 0.639 0.361
E31 Polyglandular dysfunction
0.000 0.639 0.361
E30 Disorders of puberty, not elsewhere classified
0.000 0.639 0.361
M06.48 Inflammatory polyarthropathy (Other)
0.001 0.640 0.359
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.001 0.640 0.359
M06.46 Inflammatory polyarthropathy (Lower leg)
0.001 0.640 0.359
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.001 0.640 0.359
M06.44 Inflammatory polyarthropathy (Hand)
0.001 0.640 0.359
M06.43 Inflammatory polyarthropathy (Forearm)
0.001 0.640 0.359
M06.42 Inflammatory polyarthropathy (Upper arm)
0.001 0.640 0.359
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.001 0.640 0.359
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.001 0.640 0.359
E22 Hyperfunction of pituitary gland
0.000 0.643 0.357
E50.9 Vitamin A deficiency, unspecified
0.000 0.651 0.349
E50.8 Other manifestations of vitamin A deficiency
0.000 0.651 0.349
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.651 0.349
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.651 0.349
E50.5 Vitamin A deficiency with night blindness
0.000 0.651 0.349
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.651 0.349
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.651 0.349
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.651 0.349
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.651 0.349
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.651 0.349
E51.9 Thiamine deficiency, unspecified
0.000 0.651 0.349
E51.8 Other manifestations of thiamine deficiency
0.000 0.651 0.349
E51.2 Wernicke's encephalopathy
0.000 0.651 0.349
E51.1 Beriberi
0.000 0.651 0.349
E56.9 Vitamin deficiency, unspecified
0.000 0.651 0.349
E56.8 Deficiency of other vitamins
0.000 0.651 0.349
E56.1 Deficiency of vitamin K
0.000 0.651 0.349
E56.0 Deficiency of vitamin E
0.000 0.651 0.349
E63.9 Nutritional deficiency, unspecified
0.000 0.651 0.349
E63.8 Other specified nutritional deficiencies
0.000 0.651 0.349
E63.1 Imbalance of constituents of food intake
0.000 0.651 0.349
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.651 0.349
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.651 0.349
E64.8 Sequelae of other nutritional deficiencies
0.000 0.651 0.349
E64.3 Sequelae of rickets
0.000 0.651 0.349
E64.2 Sequelae of vitamin C deficiency
0.000 0.651 0.349
E64.1 Sequelae of vitamin A deficiency
0.000 0.651 0.349
E64.0 Sequelae of protein-energy malnutrition
0.000 0.651 0.349
E55.0 Rickets, active
0.000 0.655 0.345
E61.9 Deficiency of nutrient element, unspecified
0.000 0.659 0.341
E61.8 Deficiency of other specified nutrient elements
0.000 0.659 0.341
E61.7 Deficiency of multiple nutrient elements
0.000 0.659 0.341
E61.6 Vanadium deficiency
0.000 0.659 0.341
E61.5 Molybdenum deficiency
0.000 0.659 0.341
E61.4 Chromium deficiency
0.000 0.659 0.341
E61.3 Manganese deficiency
0.000 0.659 0.341
E61.2 Magnesium deficiency
0.000 0.659 0.341
E61.0 Copper deficiency
0.000 0.659 0.341
E55.9 Vitamin D deficiency, unspecified
0.000 0.661 0.339
E07.1 Dyshormogenetic goitre
0.000 0.662 0.338
E07.0 Hypersecretion of calcitonin
0.000 0.662 0.338
E46 Unspecified protein-energy malnutrition
0.000 0.664 0.336
E27.5 Adrenomedullary hyperfunction
0.000 0.664 0.335
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.664 0.335
E27.0 Other adrenocortical overactivity
0.000 0.664 0.335
E53.8 Deficiency of other specified B group vitamins
0.000 0.665 0.335
E53.1 Pyridoxine deficiency
0.000 0.665 0.335
E53.0 Riboflavin deficiency
0.000 0.665 0.335
E61.1 Iron deficiency
0.000 0.671 0.329
E21.3 Hyperparathyroidism, unspecified
0.000 0.671 0.329
E28 Ovarian dysfunction
0.000 0.674 0.326
M05 Seropositive rheumatoid arthritis
0.003 0.676 0.320
E20.9 Hypoparathyroidism, unspecified
0.000 0.683 0.316
E44.1 Mild protein-energy malnutrition
0.000 0.684 0.315
E44.0 Moderate protein-energy malnutrition
0.000 0.684 0.315
E53.9 Vitamin B deficiency, unspecified
0.000 0.685 0.315
E26 Hyperaldosteronism
0.000 0.688 0.311
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.690 0.310
M07 Psoriatic and enteropathic arthropathies
0.003 0.691 0.306
S61.0 Open wound of finger(s) without damage to nail
0.308 0.692 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.693 0.307
E07.8 Other specified disorders of thyroid
0.000 0.696 0.304
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.001 0.699 0.300
L40.9 Psoriasis, unspecified
0.000 0.703 0.297
L40 Psoriasis
0.000 0.704 0.296
E25 Adrenogenital disorders
0.001 0.704 0.295
L40.5 Arthropathic psoriasis
0.000 0.705 0.295
E24 Cushing's syndrome
0.000 0.706 0.294
M05.9 Seropositive rheumatoid arthritis, unspecified
0.001 0.709 0.289
E22.1 Hyperprolactinaemia
0.000 0.712 0.288
E29 Testicular dysfunction
0.000 0.714 0.285
E04.2 Non-toxic multinodular goitre
0.000 0.715 0.285
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.717 0.283
E20.8 Other hypoparathyroidism
0.000 0.717 0.283
E20.1 Pseudohypoparathyroidism
0.000 0.717 0.283
E20.0 Idiopathic hypoparathyroidism
0.000 0.717 0.283
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.717 0.283
E21.4 Other specified disorders of parathyroid gland
0.000 0.717 0.283
E21.2 Other hyperparathyroidism
0.000 0.717 0.283
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.719 0.281
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.719 0.281
E16.4 Abnormal secretion of gastrin
0.000 0.719 0.281
E16.3 Increased secretion of glucagon
0.000 0.719 0.281
E04.8 Other specified non-toxic goitre
0.000 0.721 0.279
E23 Hypofunction and other disorders of pituitary gland
0.000 0.730 0.270
M07.3 Other psoriatic arthropathies
0.001 0.734 0.265
M12 Other specific arthropathies
0.004 0.735 0.261
M09 Juvenile arthritis in diseases classified elsewhere
0.004 0.735 0.261
M08 Juvenile arthritis
0.004 0.735 0.261
M14 Arthropathies in other diseases classified elsewhere
0.004 0.740 0.256
E16.1 Other hypoglycaemia
0.000 0.741 0.259
E30.9 Disorder of puberty, unspecified
0.000 0.741 0.259
E30.8 Other disorders of puberty
0.000 0.741 0.259
E30.1 Precocious puberty
0.000 0.741 0.259
E30.0 Delayed puberty
0.000 0.741 0.259
E31.9 Polyglandular dysfunction, unspecified
0.000 0.741 0.259
E31.8 Other polyglandular dysfunction
0.000 0.741 0.259
E31.1 Polyglandular hyperfunction
0.000 0.741 0.259
E31.0 Autoimmune polyglandular failure
0.000 0.741 0.259
E32.9 Disease of thymus, unspecified
0.000 0.741 0.259
E32.8 Other diseases of thymus
0.000 0.741 0.259
E32.1 Abscess of thymus
0.000 0.741 0.259
E32.0 Persistent hyperplasia of thymus
0.000 0.741 0.259
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.741 0.259
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.741 0.259
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.741 0.259
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.742 0.257
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.744 0.256
E22.8 Other hyperfunction of pituitary gland
0.000 0.744 0.256
L40.0 Psoriasis vulgaris
0.000 0.752 0.248
S61 Open wound of wrist and hand
0.248 0.752 0.000
M11 Other crystal arthropathies
0.004 0.756 0.240
E34 Other endocrine disorders
0.001 0.758 0.241
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.001 0.759 0.241
E16.2 Hypoglycaemia, unspecified
0.000 0.765 0.235
E27.9 Disorder of adrenal gland, unspecified
0.000 0.765 0.234
E28.9 Ovarian dysfunction, unspecified
0.000 0.766 0.234
E28.8 Other ovarian dysfunction
0.000 0.766 0.234
E28.3 Primary ovarian failure
0.000 0.766 0.234
E28.1 Androgen excess
0.000 0.766 0.234
E28.0 Oestrogen excess
0.000 0.766 0.234
E22.0 Acromegaly and pituitary gigantism
0.000 0.766 0.233
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.767 0.232
S61.1 Open wound of finger(s) with damage to nail
0.232 0.768 0.000
M05.8 Other seropositive rheumatoid arthritis
0.002 0.768 0.230
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.002 0.768 0.230
M05.2 Rheumatoid vasculitis
0.002 0.768 0.230
M05.1 Rheumatoid lung disease
0.002 0.768 0.230
M05.0 Felty's syndrome
0.002 0.768 0.230
E26.9 Hyperaldosteronism, unspecified
0.000 0.776 0.223
E26.8 Other hyperaldosteronism
0.000 0.776 0.223
E26.1 Secondary hyperaldosteronism
0.000 0.776 0.223
M07.6 Other enteropathic arthropathies
0.002 0.778 0.219
M07.5 Arthropathy in ulcerative colitis
0.002 0.778 0.219
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.002 0.778 0.219
M07.2 Psoriatic spondylitis
0.002 0.778 0.219
M07.1 Arthritis mutilans
0.002 0.778 0.219
M07.0 Distal interphalangeal psoriatic arthropathy
0.002 0.778 0.219
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.779 0.220
E21.0 Primary hyperparathyroidism
0.000 0.781 0.219
L40.8 Other psoriasis
0.000 0.782 0.218
M07.30 Other psoriatic arthropathies (Multiple sites)
0.001 0.785 0.214
L40.4 Guttate psoriasis
0.000 0.788 0.212
L40.3 Pustulosis palmaris et plantaris
0.000 0.788 0.212
L40.2 Acrodermatitis continua
0.000 0.788 0.212
L40.1 Generalised pustular psoriasis
0.000 0.788 0.212
E25.9 Adrenogenital disorder, unspecified
0.001 0.788 0.212
E25.8 Other adrenogenital disorders
0.001 0.788 0.212
E24.8 Other Cushing's syndrome
0.000 0.789 0.211
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.789 0.211
E24.3 Ectopic ACTH syndrome
0.000 0.789 0.211
E24.2 Drug-induced Cushing's syndrome
0.000 0.789 0.211
E24.1 Nelson's syndrome
0.000 0.789 0.211
E24.0 Pituitary-dependent Cushing's disease
0.000 0.789 0.211
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.001 0.791 0.208
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.001 0.791 0.208
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.001 0.791 0.208
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.001 0.791 0.208
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.001 0.791 0.208
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.001 0.791 0.208
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.001 0.791 0.208
M10 Gout
0.003 0.793 0.203
S61.9 Open wound of wrist and hand, part unspecified
0.206 0.794 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.795 0.205
E29.8 Other testicular dysfunction
0.000 0.795 0.205
E29.0 Testicular hyperfunction
0.000 0.795 0.205
E28.2 Polycystic ovarian syndrome
0.000 0.801 0.198
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.001 0.804 0.195
E23.7 Disorder of pituitary gland, unspecified
0.000 0.805 0.195
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.806 0.194
E23.1 Drug-induced hypopituitarism
0.000 0.806 0.194
M07.38 Other psoriatic arthropathies (Other)
0.001 0.809 0.190
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.001 0.809 0.190
M07.36 Other psoriatic arthropathies (Lower leg)
0.001 0.809 0.190
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.001 0.809 0.190
M07.34 Other psoriatic arthropathies (Hand)
0.001 0.809 0.190
M07.33 Other psoriatic arthropathies (Forearm)
0.001 0.809 0.190
M07.32 Other psoriatic arthropathies (Upper arm)
0.001 0.809 0.190
M07.31 Other psoriatic arthropathies (Shoulder region)
0.001 0.809 0.190
M08.9 Juvenile arthritis, unspecified
0.003 0.810 0.187
M08.8 Other juvenile arthritis
0.003 0.810 0.187
M08.4 Pauciarticular juvenile arthritis
0.003 0.810 0.187
M08.3 Juvenile polyarthritis (seronegative)
0.003 0.810 0.187
M08.2 Juvenile arthritis with systemic onset
0.003 0.810 0.187
M08.1 Juvenile ankylosing spondylitis
0.003 0.810 0.187
M08.0 Juvenile rheumatoid arthritis
0.003 0.810 0.187
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.003 0.810 0.187
M09.2 Juvenile arthritis in ulcerative colitis
0.003 0.810 0.187
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.003 0.810 0.187
M09.0 Juvenile arthritis in psoriasis
0.003 0.810 0.187
M12.8 Other specific arthropathies, not elsewhere classified
0.003 0.810 0.187
M12.5 Traumatic arthropathy
0.003 0.810 0.187
M12.4 Intermittent hydrarthrosis
0.003 0.810 0.187
M12.3 Palindromic rheumatism
0.003 0.810 0.187
M12.2 Villonodular synovitis (pigmented)
0.003 0.810 0.187
M12.1 Kaschin-Beck disease
0.003 0.810 0.187
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.003 0.810 0.187
E23.2 Diabetes insipidus
0.000 0.813 0.187
M14.8 Arthropathies in other specified diseases classified elsewhere
0.003 0.813 0.184
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.003 0.813 0.184
M14.4 Arthropathy in amyloidosis
0.003 0.813 0.184
M14.3 Lipoid dermatoarthritis
0.003 0.813 0.184
M14.2 Diabetic arthropathy
0.003 0.813 0.184
M14.1 Crystal arthropathy in other metabolic disorders
0.003 0.813 0.184
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.003 0.813 0.184
M14.6 Neuropathic arthropathy
0.003 0.818 0.179
M11.9 Crystal arthropathy, unspecified
0.003 0.825 0.172
M11.8 Other specified crystal arthropathies
0.003 0.825 0.172
M11.1 Familial chondrocalcinosis
0.003 0.825 0.172
M11.0 Hydroxyapatite deposition disease
0.003 0.825 0.172
E26.0 Primary hyperaldosteronism
0.001 0.825 0.174
E34.5 Androgen resistance syndrome
0.001 0.827 0.173
E34.4 Constitutional tall stature
0.001 0.827 0.173
E34.3 Short stature, not elsewhere classified
0.001 0.827 0.173
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.827 0.173
E34.1 Other hypersecretion of intestinal hormones
0.001 0.827 0.173
E23.6 Other disorders of pituitary gland
0.000 0.828 0.172
L40-L45 Papulosquamous disorders
0.000 0.828 0.172
E07.9 Disorder of thyroid, unspecified
0.001 0.831 0.168
S61.7 Multiple open wounds of wrist and hand
0.168 0.832 0.000
M13 Other arthritis
0.002 0.833 0.165
M05.09 Felty's syndrome (Site unspecified)
0.002 0.833 0.165
M05.08 Felty's syndrome (Other)
0.002 0.833 0.165
M05.07 Felty's syndrome (Ankle and foot)
0.002 0.833 0.165
M05.06 Felty's syndrome (Lower leg)
0.002 0.833 0.165
M05.05 Felty's syndrome (Pelvic region and thigh)
0.002 0.833 0.165
M05.04 Felty's syndrome (Hand)
0.002 0.833 0.165
M05.03 Felty's syndrome (Forearm)
0.002 0.833 0.165
M05.02 Felty's syndrome (Upper arm)
0.002 0.833 0.165
M05.01 Felty's syndrome (Shoulder region)
0.002 0.833 0.165
M05.00 Felty's syndrome (Multiple sites)
0.002 0.833 0.165
M05.19 Rheumatoid lung disease (Site unspecified)
0.002 0.833 0.165
M05.18 Rheumatoid lung disease (Other)
0.002 0.833 0.165
M05.17 Rheumatoid lung disease (Ankle and foot)
0.002 0.833 0.165
M05.16 Rheumatoid lung disease (Lower leg)
0.002 0.833 0.165
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.002 0.833 0.165
M05.14 Rheumatoid lung disease (Hand)
0.002 0.833 0.165
M05.13 Rheumatoid lung disease (Forearm)
0.002 0.833 0.165
M05.12 Rheumatoid lung disease (Upper arm)
0.002 0.833 0.165
M05.11 Rheumatoid lung disease (Shoulder region)
0.002 0.833 0.165
M05.10 Rheumatoid lung disease (Multiple sites)
0.002 0.833 0.165
M05.29 Rheumatoid vasculitis (Site unspecified)
0.002 0.833 0.165
M05.28 Rheumatoid vasculitis (Other)
0.002 0.833 0.165
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.002 0.833 0.165
M05.26 Rheumatoid vasculitis (Lower leg)
0.002 0.833 0.165
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.002 0.833 0.165
M05.24 Rheumatoid vasculitis (Hand)
0.002 0.833 0.165
M05.23 Rheumatoid vasculitis (Forearm)
0.002 0.833 0.165
M05.22 Rheumatoid vasculitis (Upper arm)
0.002 0.833 0.165
M05.21 Rheumatoid vasculitis (Shoulder region)
0.002 0.833 0.165
M05.20 Rheumatoid vasculitis (Multiple sites)
0.002 0.833 0.165
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.002 0.833 0.165
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.002 0.833 0.165
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.002 0.833 0.165
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.002 0.833 0.165
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.002 0.833 0.165
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.002 0.833 0.165
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.002 0.833 0.165
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.002 0.833 0.165
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.002 0.833 0.165
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.002 0.833 0.165
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.002 0.833 0.165
M05.88 Other seropositive rheumatoid arthritis (Other)
0.002 0.833 0.165
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.002 0.833 0.165
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.002 0.833 0.165
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.002 0.833 0.165
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.002 0.833 0.165
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.002 0.833 0.165
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.002 0.833 0.165
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.002 0.833 0.165
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.002 0.833 0.165
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.002 0.841 0.157
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.002 0.841 0.157
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.002 0.841 0.157

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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