TreeWAS – Variant ID: rs6456658

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
E83 Disorders of mineral metabolism	0.692	0.308	0.000
E83.4 Disorders of magnesium metabolism	0.598	0.402	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.587	0.413	0.000
E83.8 Other disorders of mineral metabolism	0.496	0.504	0.000
E83.2 Disorders of zinc metabolism	0.496	0.504	0.000
E83.0 Disorders of copper metabolism	0.496	0.504	0.000
E83.3 Disorders of phosphorus metabolism	0.476	0.524	0.000
E83.5 Disorders of calcium metabolism	0.469	0.531	0.000
B37.8 Candidiasis of other sites	0.000	0.979	0.021
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.011	0.989	0.000
H92.0 Otalgia	0.011	0.989	0.000
W22.9 Unspecified place	0.010	0.990	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.008	0.992	0.000
C44.2 Skin of ear and external auricular canal	0.008	0.992	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.007	0.993	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.006	0.994	0.000
M84.4 Pathological fracture, not elsewhere classified	0.006	0.994	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.006	0.994	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.006	0.994	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.006	0.994	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.006	0.994	0.000
D32.0 Cerebral meninges	0.006	0.994	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.005	0.995	0.000
H54.4 Blindness, one eye	0.000	0.995	0.005
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.005	0.995	0.000
A41.9 Septicaemia, unspecified	0.005	0.995	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.005	0.995	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.005	0.995	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.005	0.995	0.000
M84 Disorders of continuity of bone	0.005	0.995	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.995	0.005
F31 Bipolar affective disorder	0.000	0.995	0.005
H54.7 Unspecified visual loss	0.000	0.995	0.005
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.995	0.005
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.995	0.005
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.004	0.995	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.004	0.995	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.004	0.995	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.004	0.995	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.004	0.995	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.004	0.995	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.004	0.996	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.004	0.996	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.996	0.004
K86.0 Alcohol-induced chronic pancreatitis	0.004	0.996	0.000
S06.4 Epidural haemorrhage	0.004	0.996	0.000
G37 Other demyelinating diseases of central nervous system	0.004	0.996	0.000
H54 Blindness and low vision	0.000	0.996	0.004
M84.8 Other disorders of continuity of bone	0.004	0.996	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.996	0.004
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.996	0.004
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.996	0.004
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.004	0.996	0.000
M84.2 Delayed union of fracture	0.004	0.996	0.000
M84.3 Stress fracture, not elsewhere classified	0.004	0.996	0.000
M84.9 Disorder of continuity of bone, unspecified	0.004	0.996	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.996	0.004
H54.6 Unqualified visual loss, one eye	0.000	0.996	0.004
H54.0 Blindness, both eyes	0.000	0.996	0.004
J84.9 Interstitial pulmonary disease, unspecified	0.004	0.996	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.003	0.996	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.003	0.996	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.996	0.004
D32 Benign neoplasm of meninges	0.003	0.997	0.000
H92 Otalgia and effusion of ear	0.003	0.997	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.003	0.997	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.000
M21.26 Flexion deformity (Lower leg)	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.000	0.997	0.003
S06.41 Epidural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
G37.5 Concentric sclerosis [Balo]	0.003	0.997	0.000
G37.4 Subacute necrotising myelitis	0.003	0.997	0.000
G37.2 Central pontine myelinolysis	0.003	0.997	0.000
G37.1 Central demyelination of corpus callosum	0.003	0.997	0.000
G37.0 Diffuse sclerosis	0.003	0.997	0.000
H54.3 Unqualified visual loss, both eyes	0.000	0.997	0.003
M84.89 Other disorders of continuity of bone (Site unspecified)	0.003	0.997	0.000
M84.88 Other disorders of continuity of bone (Other)	0.003	0.997	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.003	0.997	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.003	0.997	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.003	0.997	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.003	0.997	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.003	0.997	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.003	0.997	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.003	0.997	0.000
M84.26 Delayed union of fracture (Lower leg)	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.997	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.003	0.997	0.000
M84.28 Delayed union of fracture (Other)	0.003	0.997	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.003	0.997	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.003	0.997	0.000
M84.24 Delayed union of fracture (Hand)	0.003	0.997	0.000
M84.23 Delayed union of fracture (Forearm)	0.003	0.997	0.000
M84.22 Delayed union of fracture (Upper arm)	0.003	0.997	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.003	0.997	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.003	0.997	0.000
D32.9 Meninges, unspecified	0.003	0.997	0.000
H54.1 Blindness, one eye, low vision, other eye	0.000	0.997	0.003
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.003	0.997	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.003	0.997	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.003	0.997	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.003	0.997	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.003	0.997	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.003	0.997	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.003	0.997	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.003	0.997	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.003	0.997	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.003	0.997	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.003	0.997	0.000
D32.1 Spinal meninges	0.003	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.997	0.003
H54.5 Low vision, one eye	0.000	0.997	0.003
Z71.2 Person consulting for explanation of investigation findings	0.000	0.997	0.003
N90.4 Leukoplakia of vulva	0.000	0.997	0.003
K60.3 Anal fistula	0.000	0.997	0.003
R79.9 Abnormal finding of blood chemistry, unspecified	0.003	0.997	0.000
S22.0 Fracture of thoracic vertebra	0.003	0.997	0.000
H54.2 Low vision, both eyes	0.000	0.997	0.003
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.003	0.997	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.997	0.003
F31.7 Bipolar affective disorder, currently in remission	0.000	0.997	0.002
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.997	0.003
W22 Striking against or struck by other objects	0.003	0.997	0.000
Y85 Sequelae of transport accidents	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.003	0.997	0.000
H92.2 Otorrhagia	0.002	0.997	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.997	0.003
K86.2 Cyst of pancreas	0.003	0.997	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.997	0.002
D07.1 Vulva	0.000	0.997	0.003
O73.0 Retained placenta, without haemorrhage	0.000	0.997	0.002
Z57.2 Occupational exposure to dust	0.000	0.997	0.002
M84.0 Malunion of fracture	0.002	0.998	0.000
Z04.1 Examination and observation following transport accident	0.000	0.998	0.002
K86 Other diseases of pancreas	0.002	0.998	0.000
K31.4 Gastric diverticulum	0.000	0.998	0.002
A41.8 Other specified septicaemia	0.002	0.998	0.000
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.002	0.998	0.000
N50.1 Vascular disorders of male genital organs	0.000	0.998	0.002
H92.1 Otorrhoea	0.002	0.998	0.000
I45.5 Other specified heart block	0.000	0.998	0.002
A41.2 Septicaemia due to unspecified staphylococcus	0.002	0.998	0.000
W22.8 Other specified place	0.002	0.998	0.000
W22.6 Industrial and construction area	0.002	0.998	0.000
W22.4 Street and highway	0.002	0.998	0.000
W22.0 Home	0.002	0.998	0.000
W22.7 Farm	0.002	0.998	0.000
W22.1 Residential institution	0.002	0.998	0.000
R17 Unspecified jaundice	0.000	0.998	0.002
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
R29.6 Tendency to fall, not elsewhere classified	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
D16.1 Short bones of upper limb	0.002	0.998	0.000
A41 Other septicaemia	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
K70.4 Alcoholic hepatic failure	0.002	0.998	0.000
J33.0 Polyp of nasal cavity	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.002	0.998	0.000
S06 Intracranial injury	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.002	0.998	0.000
M72.2 Plantar fascial fibromatosis	0.002	0.998	0.000
N30.8 Other cystitis	0.000	0.998	0.002
W22.5 Trade and service area	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.000	0.998	0.002
Z57.3 Occupational exposure to other air contaminants	0.000	0.998	0.002
R82.9 Other and unspecified abnormal finding in urine	0.000	0.998	0.002
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
W22.09 Striking against or struck by other objects; Home; During unspecified activity	0.002	0.998	0.000
W22.03 Striking against or struck by other objects; Home; While engaged in other types of work	0.002	0.998	0.000
W22.41 Striking against or struck by other objects; Street and highway;While engaged in leisure activity	0.002	0.998	0.000
W22.62 Striking against or struck by other objects; Industrial and construction area ;While working for income	0.002	0.998	0.000
W22.88 Striking against or struck by other objects; Other specified places ;While engaged in other specified activities	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
K86.8 Other specified diseases of pancreas	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.002	0.998	0.000
W22.3 Sports and athletics area	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.002	0.998	0.000
K86.9 Disease of pancreas, unspecified	0.002	0.998	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.998	0.002
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.998	0.002
K70.3 Alcoholic cirrhosis of liver	0.002	0.998	0.000
W22.2 School, other institution and public administrative area	0.001	0.998	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.002	0.998	0.000
A41.4 Septicaemia due to anaerobes	0.002	0.998	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.002	0.998	0.000
Z57 Occupational exposure to risk-factors	0.000	0.998	0.002
D07.2 Vagina	0.000	0.998	0.002
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
D07.4 Penis	0.000	0.998	0.002
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
B02.2 Zoster with other nervous system involvement	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.000	0.998	0.002
M72.29 Plantar fascial fibromatosis-Site unspec	0.002	0.998	0.000
D45 Polycythaemia vera	0.002	0.998	0.000
M72.28 Plantar fascial fibromatosis-Other	0.002	0.998	0.000
M72.26 Plantar fascial fibromatosis-Lower Leg	0.002	0.998	0.000
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh	0.002	0.998	0.000
M72.24 Plantar fascial fibromatosis-Hand	0.002	0.998	0.000
M72.23 Plantar fascial fibromatosis-Forearm	0.002	0.998	0.000
M72.22 Plantar fascial fibromatosis-Upper arm	0.002	0.998	0.000
M72.21 Plantar fascial fibromatosis-Shldr region	0.002	0.998	0.000
M72.20 Plantar fascial fibromatosis-Mult sites	0.002	0.998	0.000
A40 Streptococcal septicaemia	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.001	0.998	0.000
A40.1 Septicaemia due to streptococcus, group B	0.002	0.998	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.998	0.002
E70-E90 Metabolic disorders	0.002	0.998	0.000
A40.2 Septicaemia due to streptococcus, group D	0.002	0.998	0.000
K70 Alcoholic liver disease	0.002	0.998	0.000
D16.9 Bone and articular cartilage, unspecified	0.002	0.998	0.000
R85.5 Abnormal microbiological findings	0.000	0.998	0.002
S06.2 Diffuse brain injury	0.002	0.998	0.000
S06.0 Concussion	0.002	0.998	0.000
D25.0 Submucous leiomyoma of uterus	0.002	0.998	0.000
S10.9 Superficial injury of neck, part unspecified	0.002	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
D07.6 Other and unspecified male genital organs	0.000	0.998	0.001
D07.3 Other and unspecified female genital organs	0.000	0.998	0.001
D07.0 Endometrium	0.000	0.998	0.001
G59.0 Diabetic mononeuropathy	0.000	0.998	0.002
I70.0 Atherosclerosis of aorta	0.002	0.998	0.000
M85.20 Hyperostosis of skull-Mult sites	0.001	0.998	0.000
A40.0 Septicaemia due to streptococcus, group A	0.001	0.998	0.000
D07.5 Prostate	0.000	0.998	0.002
M85.2 Hyperostosis of skull	0.001	0.998	0.000
S06.8 Other intracranial injuries	0.001	0.998	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.002	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.001	0.998	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.998	0.001
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.998	0.001
Z57.7 Occupational exposure to vibration	0.000	0.998	0.001
Z57.6 Occupational exposure to extreme temperature	0.000	0.998	0.001
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.998	0.001
Z57.1 Occupational exposure to radiation	0.000	0.998	0.001
Z57.0 Occupational exposure to noise	0.000	0.998	0.001
M85.22 Hyperostosis of skull-Upper arm	0.001	0.998	0.000
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.001	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.001	0.998	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.001	0.998	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.998	0.002
E74 Other disorders of carbohydrate metabolism	0.001	0.998	0.000
E72 Other disorders of amino-acid metabolism	0.001	0.998	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.001	0.998	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.001	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.998	0.001
K70.2 Alcoholic fibrosis and sclerosis of liver	0.001	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.998	0.001
L02 Cutaneous abscess, furuncle and carbuncle	0.002	0.998	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.001	0.999	0.000
I49.5 Sick sinus syndrome	0.000	0.999	0.001
M85.0 Fibrous dysplasia (monostotic)	0.001	0.999	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.001	0.999	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.999	0.001
D16.4 Bones of skull and face	0.001	0.999	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.001	0.999	0.000
D16 Benign neoplasm of bone and articular cartilage	0.001	0.999	0.000
E70 Disorders of aromatic amino-acid metabolism	0.001	0.999	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.001	0.999	0.000
A40.9 Streptococcal septicaemia, unspecified	0.001	0.999	0.000
G36.0 Neuromyelitis optica [Devic]	0.001	0.999	0.000
J84.8 Other specified interstitial pulmonary diseases	0.001	0.999	0.000
M21.2 Flexion deformity	0.001	0.999	0.000
N04.9 Unspecified	0.000	0.999	0.001
E79 Disorders of purine and pyrimidine metabolism	0.001	0.999	0.000
E77 Disorders of glycoprotein metabolism	0.001	0.999	0.000
E76 Disorders of glycosaminoglycan metabolism	0.001	0.999	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.001	0.999	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.001	0.999	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.001	0.999	0.000
R82 Other abnormal findings in urine	0.000	0.999	0.001
M83.80 Other adult osteomalacia (Multiple sites)	0.001	0.999	0.000
S06.01 Concussion (with open intracranial wound)	0.001	0.999	0.000
D16.2 Long bones of lower limb	0.001	0.999	0.000
M85.9 Disorder of bone density and structure, unspecified	0.001	0.999	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.001	0.999	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.999	0.001
S06.21 Diffuse brain injury (with open intracranial wound)	0.001	0.999	0.000
E72.0 Disorders of amino-acid transport	0.001	0.999	0.000
E80.1 Porphyria cutanea tarda	0.001	0.999	0.000
E73 Lactose intolerance	0.001	0.999	0.000
M85 Other disorders of bone density and structure	0.001	0.999	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.001	0.999	0.000
A40.8 Other streptococcal septicaemia	0.001	0.999	0.000
D16.5 Lower jaw bone	0.001	0.999	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.001	0.999	0.000
K59.8 Other specified functional intestinal disorders	0.001	0.999	0.000
S81.0 Open wound of knee	0.000	0.999	0.001
M85.29 Hyperostosis of skull-Site unspec	0.001	0.999	0.000
M85.28 Hyperostosis of skull-Other	0.001	0.999	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.001	0.999	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.001	0.999	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.001	0.999	0.000
M85.24 Hyperostosis of skull-Hand	0.001	0.999	0.000
M85.23 Hyperostosis of skull-Forearm	0.001	0.999	0.000
M85.21 Hyperostosis of skull-Shldr region	0.001	0.999	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.001	0.999	0.000
E84 Cystic fibrosis	0.001	0.999	0.000
H93.1 Tinnitus	0.000	0.999	0.001
M83.8 Other adult osteomalacia	0.001	0.999	0.000
O36.6 Maternal care for excessive foetal growth	0.001	0.999	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.999	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.001	0.999	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.001	0.999	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.001	0.999	0.000
E72.5 Disorders of glycine metabolism	0.001	0.999	0.000
E72.4 Disorders of ornithine metabolism	0.001	0.999	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.001	0.999	0.000
E72.2 Disorders of urea cycle metabolism	0.001	0.999	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.001	0.999	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.001	0.999	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.001	0.999	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.001	0.999	0.000
E74.2 Disorders of galactose metabolism	0.001	0.999	0.000
E74.1 Disorders of fructose metabolism	0.001	0.999	0.000
E74.0 Glycogen storage disease	0.001	0.999	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.001	0.999	0.000
F20 Schizophrenia	0.000	0.999	0.001
G36 Other acute disseminated demyelination	0.001	0.999	0.000
M21.29 Flexion deformity (Site unspecified)	0.001	0.999	0.000
M21.28 Flexion deformity (Other)	0.001	0.999	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.001	0.999	0.000
M21.23 Flexion deformity (Forearm)	0.001	0.999	0.000
M21.22 Flexion deformity (Upper arm)	0.001	0.999	0.000
M21.21 Flexion deformity (Shoulder region)	0.001	0.999	0.000
M21.20 Flexion deformity (Multiple sites)	0.001	0.999	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.001	0.999	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.001	0.999	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.001	0.999	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.001	0.999	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.001	0.999	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.001	0.999	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.001	0.999	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.001	0.999	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.001	0.999	0.000
D16.8 Pelvic bones, sacrum and coccyx	0.001	0.999	0.000
D16.7 Ribs, sternum and clavicle	0.001	0.999	0.000
D16.6 Vertebral column	0.001	0.999	0.000
D16.0 Scapula and long bones of upper limb	0.001	0.999	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.001	0.999	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.001	0.999	0.000
E70.3 Albinism	0.001	0.999	0.000
E70.2 Disorders of tyrosine metabolism	0.001	0.999	0.000
E70.1 Other hyperphenylalaninaemias	0.001	0.999	0.000
E70.0 Classical phenylketonuria	0.001	0.999	0.000
E71.3 Disorders of fatty-acid metabolism	0.001	0.999	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.001	0.999	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.001	0.999	0.000
E71.0 Maple-syrup-urine disease	0.001	0.999	0.000
E75.6 Lipid storage disorder, unspecified	0.001	0.999	0.000
E75.5 Other lipid storage disorders	0.001	0.999	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.001	0.999	0.000
E75.3 Sphingolipidosis, unspecified	0.001	0.999	0.000
E75.2 Other sphingolipidosis	0.001	0.999	0.000
E75.1 Other gangliosidosis	0.001	0.999	0.000
E75.0 GM2 gangliosidosis	0.001	0.999	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.001	0.999	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.001	0.999	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.001	0.999	0.000
E76.2 Other mucopolysaccharidoses	0.001	0.999	0.000
E76.1 Mucopolysaccharidosis, type II	0.001	0.999	0.000
E76.0 Mucopolysaccharidosis, type I	0.001	0.999	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.001	0.999	0.000
E77.8 Other disorders of glycoprotein metabolism	0.001	0.999	0.000
E77.1 Defects in glycoprotein degradation	0.001	0.999	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.001	0.999	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.001	0.999	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.001	0.999	0.000
E79.1 Lesch-Nyhan syndrome	0.001	0.999	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.001	0.999	0.000
E85.9 Amyloidosis, unspecified	0.000	0.999	0.001
K70.1 Alcoholic hepatitis	0.001	0.999	0.000
M85.4 Solitary bone cyst	0.001	0.999	0.000
W29.5 Trade and service area	0.001	0.999	0.000
Y43.4 Immunosuppressive agents	0.000	0.999	0.001
Y85.0 Sequelae of motor-vehicle accident	0.001	0.999	0.000
M83 Adult osteomalacia	0.001	0.999	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.001	0.999	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.001	0.999	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.001	0.999	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.001	0.999	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.001	0.999	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.001	0.999	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.001	0.999	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.001	0.999	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.001	0.999	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.000	0.999	0.001
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.999	0.001
R82.4 Acetonuria	0.000	0.999	0.001
R82.3 Haemoglobinuria	0.000	0.999	0.001
R82.2 Biliuria	0.000	0.999	0.001
R82.0 Chyluria	0.000	0.999	0.001
B23.8 HIV disease resulting in other specified conditions	0.001	0.999	0.000
E11.5 With peripheral circulatory complications	0.000	0.999	0.001
E73.8 Other lactose intolerance	0.001	0.999	0.000
E73.1 Secondary lactase deficiency	0.001	0.999	0.000
E73.0 Congenital lactase deficiency	0.001	0.999	0.000
K11.5 Sialolithiasis	0.000	0.999	0.001
M85.5 Aneurysmal bone cyst	0.001	0.999	0.000
M85.3 Osteitis condensans	0.001	0.999	0.000
M85.1 Skeletal fluorosis	0.001	0.999	0.000
R82.1 Myoglobinuria	0.000	0.999	0.001
E80 Disorders of porphyrin and bilirubin metabolism	0.001	0.999	0.000
S06.00 Concussion (without open intracranial wound)	0.001	0.999	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.001	0.999	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.999	0.001
E84.8 Cystic fibrosis with other manifestations	0.001	0.999	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.001	0.999	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.001	0.999	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.999	0.001
M83.1 Senile osteomalacia	0.001	0.999	0.000
E85 Amyloidosis	0.001	0.999	0.001
J84 Other interstitial pulmonary diseases	0.001	0.999	0.000
M83.12 Senile osteomalacia (Upper arm)	0.001	0.999	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.001	0.999	0.000
M83.88 Other adult osteomalacia (Other)	0.001	0.999	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.001	0.999	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.001	0.999	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.001	0.999	0.000
M83.84 Other adult osteomalacia (Hand)	0.001	0.999	0.000
M83.83 Other adult osteomalacia (Forearm)	0.001	0.999	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.001	0.999	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.001	0.999	0.000
M85.46 Solitary bone cyst (Lower leg)	0.001	0.999	0.000
F20.5 Residual schizophrenia	0.000	0.999	0.001
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
E80.6 Other disorders of bilirubin metabolism	0.001	0.999	0.000
G36.9 Acute disseminated demyelination, unspecified	0.001	0.999	0.000
G36.8 Other specified acute disseminated demyelination	0.001	0.999	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.001	0.999	0.000
H43.8 Other disorders of vitreous body	0.000	0.999	0.001
I49.9 Cardiac arrhythmia, unspecified	0.001	0.999	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.001	0.999	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.001	0.999	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.001	0.999	0.000
M85.48 Solitary bone cyst (Other)	0.001	0.999	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.001	0.999	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.001	0.999	0.000
M85.44 Solitary bone cyst (Hand)	0.001	0.999	0.000
M85.43 Solitary bone cyst (Forearm)	0.001	0.999	0.000
M85.42 Solitary bone cyst (Upper arm)	0.001	0.999	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.001	0.999	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.001	0.999	0.000
E73.9 Lactose intolerance, unspecified	0.001	0.999	0.000
E85.3 Secondary systemic amyloidosis	0.000	0.999	0.001
E88.1 Lipodystrophy, not elsewhere classified	0.001	0.999	0.000
F20.6 Simple schizophrenia	0.000	0.999	0.001
F20.4 Postschizophrenic depression	0.000	0.999	0.001
F20.3 Undifferentiated schizophrenia	0.000	0.999	0.001
F20.2 Catatonic schizophrenia	0.000	0.999	0.001
F20.1 Hebephrenic schizophrenia	0.000	0.999	0.001
G53.0 Postzoster neuralgia	0.001	0.999	0.000
K04.8 Radicular cyst	0.001	0.999	0.000
M83.9 Adult osteomalacia, unspecified	0.001	0.999	0.000
M83.5 Other drug-induced osteomalacia in adults	0.001	0.999	0.000
M83.4 Aluminum bone disease	0.001	0.999	0.000
M83.3 Adult osteomalacia due to malnutrition	0.001	0.999	0.000
M83.2 Adult osteomalacia due to malabsorption	0.001	0.999	0.000
M83.0 Puerperal osteomalacia	0.001	0.999	0.000
Z54.0 Convalescence following surgery	0.000	0.999	0.001
T91 Sequelae of injuries of neck and trunk	0.001	0.999	0.000
M80-M85 Disorders of bone density and structure	0.001	0.999	0.000
B35.3 Tinea pedis	0.001	0.999	0.000
G93.4 Encephalopathy, unspecified	0.001	0.999	0.000
I67.8 Other specified cerebrovascular diseases	0.001	0.999	0.000
I84.4 External haemorrhoids with other complications	0.001	0.999	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.999	0.001
S06.5 Traumatic subdural haemorrhage	0.001	0.999	0.000
S11.9 Open wound of neck, part unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations