TreeWAS – Variant ID: rs6457009

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
G35 Multiple sclerosis	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.001	0.999
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.042	0.958
G37 Other demyelinating diseases of central nervous system	0.000	0.050	0.950
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.065	0.935
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.138	0.862
G36 Other acute disseminated demyelination	0.000	0.301	0.699
G37.5 Concentric sclerosis [Balo]	0.000	0.319	0.681
G37.4 Subacute necrotising myelitis	0.000	0.319	0.681
G37.2 Central pontine myelinolysis	0.000	0.319	0.681
G37.1 Central demyelination of corpus callosum	0.000	0.319	0.681
G37.0 Diffuse sclerosis	0.000	0.319	0.681
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.391	0.609
E05.9 Thyrotoxicosis, unspecified	0.000	0.448	0.552
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.452	0.548
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.465	0.535
G36.0 Neuromyelitis optica [Devic]	0.000	0.487	0.513
G36.9 Acute disseminated demyelination, unspecified	0.000	0.499	0.501
G36.8 Other specified acute disseminated demyelination	0.000	0.499	0.501
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.499	0.501
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.507	0.493
I84.9 Unspecified haemorrhoids without complication	0.457	0.543	0.000
E00-E07 Disorders of thyroid gland	0.000	0.567	0.433
E06 Thyroiditis	0.000	0.570	0.430
E06.3 Autoimmune thyroiditis	0.000	0.587	0.413
E06.9 Thyroiditis, unspecified	0.000	0.599	0.401
E05.5 Thyroid crisis or storm	0.000	0.607	0.393
E05.4 Thyrotoxicosis factitia	0.000	0.607	0.393
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.607	0.393
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.607	0.393
E05.8 Other thyrotoxicosis	0.000	0.638	0.362
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.659	0.341
E06.5 Other chronic thyroiditis	0.000	0.671	0.329
E07 Other disorders of thyroid	0.000	0.675	0.325
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.689	0.311
E00 Congenital iodine-deficiency syndrome	0.000	0.689	0.311
E06.4 Drug-induced thyroiditis	0.000	0.692	0.308
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.692	0.308
E06.0 Acute thyroiditis	0.000	0.692	0.308
E03 Other hypothyroidism	0.000	0.702	0.298
E06.1 Subacute thyroiditis	0.000	0.713	0.286
K90 Intestinal malabsorption	0.000	0.721	0.279
S06.3 Focal brain injury	0.000	0.733	0.267
E07.8 Other specified disorders of thyroid	0.000	0.742	0.258
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.762	0.238
E03.9 Hypothyroidism, unspecified	0.000	0.766	0.234
E07.1 Dyshormogenetic goitre	0.000	0.767	0.233
E07.0 Hypersecretion of calcitonin	0.000	0.767	0.233
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.769	0.231
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.777	0.223
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.777	0.223
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.777	0.223
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.777	0.223
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.777	0.223
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.777	0.223
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.777	0.223
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.777	0.223
E07.9 Disorder of thyroid, unspecified	0.000	0.783	0.217
S06 Intracranial injury	0.000	0.785	0.215
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.786	0.214
E03.5 Myxoedema coma	0.000	0.786	0.214
E03.4 Atrophy of thyroid (acquired)	0.000	0.786	0.214
E03.3 Postinfectious hypothyroidism	0.000	0.786	0.214
S06.5 Traumatic subdural haemorrhage	0.000	0.795	0.205
K90.8 Other intestinal malabsorption	0.000	0.797	0.203
K90.3 Pancreatic steatorrhoea	0.000	0.800	0.200
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.800	0.200
K90.1 Tropical sprue	0.000	0.800	0.200
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.801	0.199
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.808	0.192
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.810	0.190
K90.9 Intestinal malabsorption, unspecified	0.000	0.812	0.187
E03.8 Other specified hypothyroidism	0.000	0.816	0.184
E83 Disorders of mineral metabolism	0.000	0.821	0.179
E03.1 Congenital hypothyroidism without goitre	0.000	0.824	0.176
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.828	0.172
S06.1 Traumatic cerebral oedema	0.000	0.836	0.164
S06.7 Intracranial injury with prolonged coma	0.000	0.846	0.154
S06.9 Intracranial injury, unspecified	0.000	0.848	0.152
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.852	0.147
M35.0 Sicca syndrome [Sjogren]	0.000	0.854	0.146
S06.4 Epidural haemorrhage	0.000	0.855	0.144
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.863	0.136
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.863	0.136
S06.2 Diffuse brain injury	0.000	0.864	0.136
S06.0 Concussion	0.000	0.865	0.135
E83.8 Other disorders of mineral metabolism	0.000	0.872	0.128
E83.2 Disorders of zinc metabolism	0.000	0.872	0.128
E83.0 Disorders of copper metabolism	0.000	0.872	0.128
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.872	0.128
S06.8 Other intracranial injuries	0.000	0.873	0.127
E83.3 Disorders of phosphorus metabolism	0.000	0.877	0.123
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.880	0.120
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.882	0.118
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.889	0.111
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.889	0.111
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.891	0.109
E83.5 Disorders of calcium metabolism	0.000	0.892	0.108
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.894	0.106
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.896	0.104
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.902	0.098
S06.01 Concussion (with open intracranial wound)	0.000	0.903	0.097
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.906	0.094
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.909	0.091
K50.9 Crohn's disease, unspecified	0.079	0.921	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.921	0.079
S06.00 Concussion (without open intracranial wound)	0.000	0.923	0.077
E89.0 Postprocedural hypothyroidism	0.000	0.924	0.076
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.929	0.071
E70-E90 Metabolic disorders	0.000	0.929	0.071
K50 Crohn's disease [regional enteritis]	0.071	0.929	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.930	0.070
K50.8 Other Crohn's disease	0.067	0.933	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.936	0.064
E89.2 Postprocedural hypoparathyroidism	0.000	0.937	0.063
E04 Other non-toxic goitre	0.000	0.938	0.062
K51.2 Ulcerative (chronic) proctitis	0.061	0.939	0.000
K51 Ulcerative colitis	0.060	0.940	0.000
E40-E46 Malnutrition	0.000	0.941	0.058
K50-K52 Noninfective enteritis and colitis	0.057	0.943	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.055	0.945	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.946	0.054
E89.4 Postprocedural ovarian failure	0.000	0.947	0.053
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.949	0.051
E89.1 Postprocedural hypoinsulinaemia	0.000	0.949	0.051
E77 Disorders of glycoprotein metabolism	0.000	0.949	0.051
E76 Disorders of glycosaminoglycan metabolism	0.000	0.949	0.051
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.949	0.051
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.949	0.051
E46 Unspecified protein-energy malnutrition	0.000	0.950	0.050
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.950	0.050
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.950	0.050
E73 Lactose intolerance	0.000	0.950	0.050
E70 Disorders of aromatic amino-acid metabolism	0.000	0.950	0.050
E84 Cystic fibrosis	0.000	0.953	0.047
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.953	0.047
K51.1 Ulcerative (chronic) ileocolitis	0.047	0.953	0.000
K51.8 Other ulcerative colitis	0.047	0.953	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.954	0.046
K50.1 Crohn's disease of large intestine	0.046	0.954	0.000
E72 Other disorders of amino-acid metabolism	0.000	0.954	0.046
K51.5 Mucosal proctocolitis	0.046	0.954	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.955	0.045
E04.8 Other specified non-toxic goitre	0.000	0.955	0.045
K51.4 Pseudopolyposis of colon	0.045	0.955	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.956	0.044
E79 Disorders of purine and pyrimidine metabolism	0.000	0.956	0.044
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.958	0.042
E45 Retarded development following protein-energy malnutrition	0.000	0.958	0.042
E43 Unspecified severe protein-energy malnutrition	0.000	0.958	0.042
E42 Marasmic kwashiorkor	0.000	0.958	0.042
E41 Nutritional marasmus	0.000	0.958	0.042
E40 Kwashiorkor	0.000	0.958	0.042
I71 Aortic aneurysm and dissection	0.000	0.960	0.040
E80.6 Other disorders of bilirubin metabolism	0.000	0.961	0.039
E89.5 Postprocedural testicular hypofunction	0.000	0.962	0.038
E75.5 Other lipid storage disorders	0.000	0.962	0.038
E71.3 Disorders of fatty-acid metabolism	0.000	0.963	0.037
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.963	0.037
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.963	0.037
E71.0 Maple-syrup-urine disease	0.000	0.963	0.037
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.963	0.037
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.963	0.037
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.963	0.037
E76.2 Other mucopolysaccharidoses	0.000	0.963	0.037
E76.1 Mucopolysaccharidosis, type II	0.000	0.963	0.037
E76.0 Mucopolysaccharidosis, type I	0.000	0.963	0.037
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.963	0.037
E77.8 Other disorders of glycoprotein metabolism	0.000	0.963	0.037
E77.1 Defects in glycoprotein degradation	0.000	0.963	0.037
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.963	0.037
E75.6 Lipid storage disorder, unspecified	0.000	0.964	0.036
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.964	0.036
E75.3 Sphingolipidosis, unspecified	0.000	0.964	0.036
E75.1 Other gangliosidosis	0.000	0.964	0.036
E75.0 GM2 gangliosidosis	0.000	0.964	0.036
E73.8 Other lactose intolerance	0.000	0.964	0.036
E73.1 Secondary lactase deficiency	0.000	0.964	0.036
E73.0 Congenital lactase deficiency	0.000	0.964	0.036
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.964	0.036
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.964	0.036
E70.2 Disorders of tyrosine metabolism	0.000	0.964	0.036
E70.1 Other hyperphenylalaninaemias	0.000	0.964	0.036
E70.0 Classical phenylketonuria	0.000	0.964	0.036
E80.1 Porphyria cutanea tarda	0.000	0.964	0.036
E84.9 Cystic fibrosis, unspecified	0.000	0.964	0.036
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.965	0.035
K51.9 Ulcerative colitis, unspecified	0.035	0.965	0.000
E70.3 Albinism	0.000	0.965	0.034
E73.9 Lactose intolerance, unspecified	0.000	0.965	0.034
E88 Other metabolic disorders	0.000	0.965	0.034
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.966	0.034
E84.8 Cystic fibrosis with other manifestations	0.000	0.966	0.034
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.966	0.034
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.966	0.034
E80.5 Crigler-Najjar syndrome	0.000	0.966	0.034
E80.3 Defects of catalase and peroxydase	0.000	0.966	0.034
E80.0 Hereditary erythropoietic porphyria	0.000	0.966	0.034
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.967	0.033
M35 Other systemic involvement of connective tissue	0.000	0.967	0.033
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.967	0.033
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.967	0.033
E72.5 Disorders of glycine metabolism	0.000	0.967	0.033
E72.4 Disorders of ornithine metabolism	0.000	0.967	0.033
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.967	0.033
E72.2 Disorders of urea cycle metabolism	0.000	0.967	0.033
K50.0 Crohn's disease of small intestine	0.033	0.967	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.967	0.033
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.967	0.033
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.967	0.033
E74.2 Disorders of galactose metabolism	0.000	0.967	0.033
E74.1 Disorders of fructose metabolism	0.000	0.967	0.033
E72.0 Disorders of amino-acid transport	0.000	0.968	0.032
E75.2 Other sphingolipidosis	0.000	0.968	0.032
E74.0 Glycogen storage disease	0.000	0.968	0.032
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.968	0.032
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.968	0.032
E79.1 Lesch-Nyhan syndrome	0.000	0.968	0.032
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.969	0.031
E89.3 Postprocedural hypopituitarism	0.000	0.969	0.031
E44.1 Mild protein-energy malnutrition	0.000	0.969	0.030
E44.0 Moderate protein-energy malnutrition	0.000	0.969	0.030
E80.2 Other porphyria	0.000	0.970	0.029
I72 Other aneurysm	0.000	0.971	0.029
M35.7 Hypermobility syndrome	0.000	0.971	0.029
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.971	0.029
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.971	0.029
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.971	0.028
I73 Other peripheral vascular diseases	0.000	0.971	0.029
I73.9 Peripheral vascular disease, unspecified	0.000	0.971	0.029
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.972	0.028
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.972	0.028
I72.4 Aneurysm of artery of lower extremity	0.000	0.972	0.028
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.972	0.028
E83.4 Disorders of magnesium metabolism	0.000	0.972	0.028
E86 Volume depletion	0.000	0.972	0.028
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.973	0.027
E88.9 Metabolic disorder, unspecified	0.000	0.973	0.027
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.973	0.027
K51.3 Ulcerative (chronic) rectosigmoiditis	0.026	0.974	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.974	0.025
E88.2 Lipomatosis, not elsewhere classified	0.000	0.975	0.025
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.975	0.025
I72.9 Aneurysm of unspecified site	0.000	0.975	0.025
E65-E68 Obesity and other hyperalimentation	0.000	0.975	0.025
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.976	0.024
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.976	0.024
M35.5 Multifocal fibrosclerosis	0.000	0.976	0.024
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.976	0.024
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.976	0.024
E04.9 Non-toxic goitre, unspecified	0.000	0.976	0.024
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.976	0.024
I72.1 Aneurysm of artery of upper extremity	0.000	0.976	0.024
I74 Arterial embolism and thrombosis	0.000	0.976	0.024
I70 Atherosclerosis	0.000	0.976	0.024
E88.3 Tumour lysis syndrome	0.000	0.977	0.023
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.977	0.023
I72.8 Aneurysm of other specified arteries	0.000	0.978	0.022
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.978	0.022
E80.4 Gilbert's syndrome	0.000	0.978	0.022
I71.0 Dissection of aorta [any part]	0.000	0.978	0.022
M35.1 Other overlap syndromes	0.000	0.978	0.022
I74.8 Embolism and thrombosis of other arteries	0.000	0.978	0.022
E88.8 Other specified metabolic disorders	0.000	0.978	0.021
E85 Amyloidosis	0.001	0.978	0.021
K90-K93 Other diseases of the digestive system	0.000	0.979	0.021
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.979	0.021
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.979	0.021
M35.8 Other specified systemic involvement of connective tissue	0.000	0.979	0.021
M35.2 Behcet's disease	0.000	0.979	0.021
I72.2 Aneurysm of renal artery	0.000	0.979	0.021
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.980	0.020
I70.8 Atherosclerosis of other arteries	0.000	0.980	0.020
I73.8 Other specified peripheral vascular diseases	0.000	0.981	0.019
I79.1 Aortitis in diseases classified elsewhere	0.000	0.981	0.019
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.981	0.019
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.981	0.019
E50-E64 Other nutritional deficiencies	0.000	0.982	0.018
E67 Other hyperalimentation	0.000	0.982	0.018
E68 Sequelae of hyperalimentation	0.000	0.982	0.018
E04.2 Non-toxic multinodular goitre	0.000	0.982	0.018
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.982	0.018
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.982	0.018
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.982	0.017
I72.3 Aneurysm of iliac artery	0.000	0.983	0.017
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.983	0.017
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.983	0.017
I70.1 Atherosclerosis of renal artery	0.000	0.983	0.017
I70.9 Generalised and unspecified atherosclerosis	0.000	0.983	0.017
I72.0 Aneurysm of carotid artery	0.000	0.983	0.017
I70.0 Atherosclerosis of aorta	0.000	0.984	0.016
E85.8 Other amyloidosis	0.001	0.984	0.016
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.984	0.016
E27.1 Primary adrenocortical insufficiency	0.000	0.984	0.016
E85.2 Heredofamilial amyloidosis, unspecified	0.001	0.984	0.015
E85.1 Neuropathic heredofamilial amyloidosis	0.001	0.984	0.015
E85.0 Nonneuropathic heredofamilial amyloidosis	0.001	0.984	0.015
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.984	0.016
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.984	0.016
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.984	0.016
I77 Other disorders of arteries and arterioles	0.000	0.985	0.015
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.985	0.014
E65 Localised adiposity	0.000	0.985	0.014
E20-E35 Disorders of other endocrine glands	0.000	0.985	0.015
E51 Thiamine deficiency	0.000	0.986	0.014
I77.2 Rupture of artery	0.000	0.986	0.014
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.986	0.014
B37.9 Candidiasis, unspecified	0.000	0.986	0.014
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.011	0.986	0.002
G61.0 Guillain-Barre syndrome	0.013	0.987	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.987	0.013
E63 Other nutritional deficiencies	0.000	0.987	0.013
E50 Vitamin A deficiency	0.000	0.987	0.013
E60 Dietary zinc deficiency	0.000	0.987	0.013
E59 Dietary selenium deficiency	0.000	0.987	0.013
E52 Niacin deficiency [pellagra]	0.000	0.987	0.013
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.987	0.013
E56 Other vitamin deficiencies	0.000	0.987	0.013
E67.8 Other specified hyperalimentation	0.000	0.987	0.013
E67.3 Hypervitaminosis D	0.000	0.987	0.013
E67.2 Megavitamin-B6 syndrome	0.000	0.987	0.013
E67.1 Hypercarotenaemia	0.000	0.987	0.013
E67.0 Hypervitaminosis A	0.000	0.987	0.013
G61 Inflammatory polyneuropathy	0.013	0.987	0.001
E27 Other disorders of adrenal gland	0.000	0.987	0.013
G60.0 Hereditary motor and sensory neuropathy	0.013	0.987	0.000
E20 Hypoparathyroidism	0.000	0.987	0.013
R31 Unspecified haematuria	0.013	0.987	0.000
E85.3 Secondary systemic amyloidosis	0.001	0.987	0.012
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.987	0.013
I73.0 Raynaud's syndrome	0.000	0.987	0.013
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.987	0.013
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.987	0.012
G60 Hereditary and idiopathic neuropathy	0.011	0.987	0.001
G63 Polyneuropathy in diseases classified elsewhere	0.011	0.988	0.001
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.988	0.012
E25 Adrenogenital disorders	0.000	0.988	0.012
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.988	0.012
E58 Dietary calcium deficiency	0.000	0.988	0.012
E54 Ascorbic acid deficiency	0.000	0.988	0.012
E20.9 Hypoparathyroidism, unspecified	0.000	0.988	0.012
B37 Candidiasis	0.000	0.988	0.012
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.988	0.012
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.988	0.011
I77.8 Other specified disorders of arteries and arterioles	0.000	0.988	0.012
G63.2 Diabetic polyneuropathy	0.012	0.988	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.988	0.011
K93.1 Megacolon in Chagas' disease	0.000	0.988	0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.988	0.011
E51.2 Wernicke's encephalopathy	0.000	0.989	0.011
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.989	0.011
B37.3 Candidiasis of vulva and vagina	0.000	0.989	0.011
G61.8 Other inflammatory polyneuropathies	0.011	0.989	0.000
B37.0 Candidal stomatitis	0.000	0.989	0.011
E78.4 Other hyperlipidaemia	0.000	0.989	0.011
I77.5 Necrosis of artery	0.000	0.989	0.011
I77.4 Coeliac artery compression syndrome	0.000	0.989	0.011
I77.3 Arterial fibromuscular dysplasia	0.000	0.989	0.011
N76 Other inflammation of vagina and vulva	0.000	0.989	0.011
E23 Hypofunction and other disorders of pituitary gland	0.000	0.989	0.011
B37.8 Candidiasis of other sites	0.000	0.989	0.011
E55 Vitamin D deficiency	0.000	0.989	0.011
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.989	0.011
E32 Diseases of thymus	0.000	0.989	0.011
E31 Polyglandular dysfunction	0.000	0.989	0.011
E30 Disorders of puberty, not elsewhere classified	0.000	0.989	0.011
E16 Other disorders of pancreatic internal secretion	0.000	0.989	0.010
N76.8 Other specified inflammation of vagina and vulva	0.000	0.989	0.011
E51.9 Thiamine deficiency, unspecified	0.000	0.989	0.010
E51.8 Other manifestations of thiamine deficiency	0.000	0.989	0.010
E51.1 Beriberi	0.000	0.989	0.010
E78.6 Lipoprotein deficiency	0.000	0.989	0.010
N76.2 Acute vulvitis	0.000	0.990	0.010
G61.9 Inflammatory polyneuropathy, unspecified	0.010	0.990	0.000
E85.4 Organ-limited amyloidosis	0.001	0.990	0.009
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.990	0.010
E78.3 Hyperchylomicronaemia	0.000	0.990	0.010
N76.3 Subacute and chronic vulvitis	0.000	0.990	0.010
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.990	0.010
E50.9 Vitamin A deficiency, unspecified	0.000	0.990	0.010
E50.8 Other manifestations of vitamin A deficiency	0.000	0.990	0.010
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.990	0.010
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.990	0.010
E50.5 Vitamin A deficiency with night blindness	0.000	0.990	0.010
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.990	0.010
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.990	0.010
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.990	0.010
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.990	0.010
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.990	0.010
E63.9 Nutritional deficiency, unspecified	0.000	0.990	0.010
E63.8 Other specified nutritional deficiencies	0.000	0.990	0.010
E63.1 Imbalance of constituents of food intake	0.000	0.990	0.010
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.990	0.010
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.990	0.010
E64.8 Sequelae of other nutritional deficiencies	0.000	0.990	0.010
E64.3 Sequelae of rickets	0.000	0.990	0.010
E64.2 Sequelae of vitamin C deficiency	0.000	0.990	0.010
E64.1 Sequelae of vitamin A deficiency	0.000	0.990	0.010
E64.0 Sequelae of protein-energy malnutrition	0.000	0.990	0.010
G64 Other disorders of peripheral nervous system	0.008	0.990	0.002
E56.9 Vitamin deficiency, unspecified	0.000	0.990	0.010
E56.8 Deficiency of other vitamins	0.000	0.990	0.010
E56.0 Deficiency of vitamin E	0.000	0.990	0.010
G61.1 Serum neuropathy	0.009	0.990	0.001
N76.4 Abscess of vulva	0.000	0.990	0.010
A08.4 Viral intestinal infection, unspecified	0.000	0.990	0.010
E53 Deficiency of other B group vitamins	0.000	0.990	0.010
E56.1 Deficiency of vitamin K	0.000	0.990	0.009
B37.7 Candidal septicaemia	0.000	0.990	0.010
E27.5 Adrenomedullary hyperfunction	0.000	0.990	0.009
E27.0 Other adrenocortical overactivity	0.000	0.990	0.009
E23.6 Other disorders of pituitary gland	0.000	0.990	0.010
E20.8 Other hypoparathyroidism	0.000	0.990	0.009
E20.1 Pseudohypoparathyroidism	0.000	0.990	0.009
E20.0 Idiopathic hypoparathyroidism	0.000	0.990	0.009
E26 Hyperaldosteronism	0.000	0.991	0.009
E78.1 Pure hyperglyceridaemia	0.000	0.991	0.009
N76.0 Acute vaginitis	0.000	0.991	0.009
G60.3 Idiopathic progressive neuropathy	0.008	0.991	0.001
G60.2 Neuropathy in association with hereditary ataxia	0.008	0.991	0.001
G60.1 Refsum's disease	0.008	0.991	0.001
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.991	0.009
E29 Testicular dysfunction	0.000	0.991	0.009
M35.3 Polymyalgia rheumatica	0.000	0.991	0.009
G63.8 Polyneuropathy in other diseases classified elsewhere	0.008	0.991	0.001
G63.6 Polyneuropathy in other musculoskeletal disorders	0.008	0.991	0.001
G63.5 Polyneuropathy in systemic connective tissue disorders	0.008	0.991	0.001
G63.4 Polyneuropathy in nutritional deficiency	0.008	0.991	0.001
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.008	0.991	0.001
G63.1 Polyneuropathy in neoplastic disease	0.008	0.991	0.001
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.008	0.991	0.001
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.008	0.991	0.001
E25.9 Adrenogenital disorder, unspecified	0.000	0.991	0.009
E25.8 Other adrenogenital disorders	0.000	0.991	0.009
B37.6 Candidal endocarditis	0.000	0.991	0.009
B37.5 Candidal meningitis	0.000	0.991	0.009
E23.7 Disorder of pituitary gland, unspecified	0.000	0.991	0.009
I78 Diseases of capillaries	0.000	0.991	0.009
E04.1 Non-toxic single thyroid nodule	0.000	0.991	0.008
I77.6 Arteritis, unspecified	0.000	0.991	0.009
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.991	0.009
N76.1 Subacute and chronic vaginitis	0.000	0.992	0.008
E10-E14 Diabetes mellitus	0.000	0.992	0.008
N76.5 Ulceration of vagina	0.000	0.992	0.008
E85.9 Amyloidosis, unspecified	0.002	0.992	0.007
E78.2 Mixed hyperlipidaemia	0.000	0.992	0.008
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.992	0.008
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.992	0.008
E23.1 Drug-induced hypopituitarism	0.000	0.992	0.008
E34 Other endocrine disorders	0.000	0.992	0.008
B37.2 Candidiasis of skin and nail	0.000	0.992	0.008
E27.2 Addisonian crisis	0.000	0.992	0.008
E55.0 Rickets, active	0.000	0.992	0.008
E30.9 Disorder of puberty, unspecified	0.000	0.992	0.008
E30.8 Other disorders of puberty	0.000	0.992	0.008
E30.1 Precocious puberty	0.000	0.992	0.008
E30.0 Delayed puberty	0.000	0.992	0.008
E31.9 Polyglandular dysfunction, unspecified	0.000	0.992	0.008
E31.8 Other polyglandular dysfunction	0.000	0.992	0.008
E31.1 Polyglandular hyperfunction	0.000	0.992	0.008
E31.0 Autoimmune polyglandular failure	0.000	0.992	0.008
E32.9 Disease of thymus, unspecified	0.000	0.992	0.008
E32.8 Other diseases of thymus	0.000	0.992	0.008
E32.1 Abscess of thymus	0.000	0.992	0.008
E32.0 Persistent hyperplasia of thymus	0.000	0.992	0.008
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.992	0.008
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.992	0.008
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.992	0.008
B37.4 Candidiasis of other urogenital sites	0.000	0.992	0.008
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.992	0.008
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.992	0.008
E16.4 Abnormal secretion of gastrin	0.000	0.992	0.008
E16.3 Increased secretion of glucagon	0.000	0.992	0.008
L43.9 Lichen planus, unspecified	0.000	0.992	0.008
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.992	0.008
G60.8 Other hereditary and idiopathic neuropathies	0.007	0.992	0.001
I77.0 Arteriovenous fistula, acquired	0.000	0.992	0.008
E61 Deficiency of other nutrient elements	0.000	0.992	0.007
E27.9 Disorder of adrenal gland, unspecified	0.000	0.992	0.007
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.993	0.007
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.993	0.007
E24 Cushing's syndrome	0.000	0.993	0.007
E53.1 Pyridoxine deficiency	0.000	0.993	0.007
E53.0 Riboflavin deficiency	0.000	0.993	0.007
E26.8 Other hyperaldosteronism	0.000	0.993	0.007
E26.1 Secondary hyperaldosteronism	0.000	0.993	0.007
E23.2 Diabetes insipidus	0.000	0.993	0.007
I74.5 Embolism and thrombosis of iliac artery	0.000	0.993	0.007
G62 Other polyneuropathies	0.004	0.993	0.003
E29.8 Other testicular dysfunction	0.000	0.993	0.007
E29.0 Testicular hyperfunction	0.000	0.993	0.007
E53.9 Vitamin B deficiency, unspecified	0.000	0.993	0.007
E26.9 Hyperaldosteronism, unspecified	0.000	0.993	0.007
E28 Ovarian dysfunction	0.000	0.993	0.006
S46.3 Injury of muscle and tendon of triceps	0.000	0.993	0.007
E13 Other specified diabetes mellitus	0.000	0.993	0.007
E29.9 Testicular dysfunction, unspecified	0.000	0.993	0.006
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.994	0.006
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.994	0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations