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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6457282
log Bayes Factor = 75.3093
Chromosome 6   position 30,857,988  (GRCh37) Explore rs6457282 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
L40.0 Psoriasis vulgaris
0.996 0.004 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.013 0.987
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.013 0.987
M07.39 Other psoriatic arthropathies (Site unspecified)
0.962 0.038 0.000
M07.3 Other psoriatic arthropathies
0.962 0.038 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.958 0.042 0.000
E10.4 With neurological complications
0.000 0.044 0.956
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.052 0.948
E16 Other disorders of pancreatic internal secretion
0.000 0.080 0.920
E10.3 With ophthalmic complications
0.000 0.086 0.914
E10.5 With peripheral circulatory complications
0.000 0.094 0.906
E10.1 With ketoacidosis
0.000 0.095 0.905
E16.2 Hypoglycaemia, unspecified
0.000 0.098 0.902
L40.8 Other psoriasis
0.894 0.106 0.000
E07 Other disorders of thyroid
0.000 0.115 0.885
L40.1 Generalised pustular psoriasis
0.856 0.144 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.847 0.153 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.164 0.836
E10.6 With other specified complications
0.000 0.169 0.831
E10.2 With renal complications
0.000 0.170 0.830
M07.36 Other psoriatic arthropathies (Lower leg)
0.823 0.177 0.000
E10.0 With coma
0.000 0.192 0.808
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.801 0.199 0.000
E06 Thyroiditis
0.000 0.199 0.801
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.202 0.798
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.255 0.744
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.269 0.731
E50-E64 Other nutritional deficiencies
0.000 0.274 0.726
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.292 0.708
M07.38 Other psoriatic arthropathies (Other)
0.689 0.310 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.689 0.310 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.689 0.310 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.689 0.310 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.689 0.310 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.320 0.680
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.340 0.660
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.340 0.660
E16.4 Abnormal secretion of gastrin
0.000 0.340 0.660
E16.3 Increased secretion of glucagon
0.000 0.340 0.660
E06.3 Autoimmune thyroiditis
0.000 0.359 0.641
E07.1 Dyshormogenetic goitre
0.000 0.365 0.635
E07.0 Hypersecretion of calcitonin
0.000 0.365 0.635
E06.9 Thyroiditis, unspecified
0.000 0.402 0.598
E03.8 Other specified hypothyroidism
0.000 0.406 0.594
E65-E68 Obesity and other hyperalimentation
0.000 0.411 0.589
E10.8 With unspecified complications
0.000 0.422 0.578
E06.5 Other chronic thyroiditis
0.000 0.426 0.574
E06.4 Drug-induced thyroiditis
0.000 0.426 0.574
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.426 0.574
E06.1 Subacute thyroiditis
0.000 0.426 0.574
E06.0 Acute thyroiditis
0.000 0.426 0.574
E55 Vitamin D deficiency
0.000 0.427 0.573
E13 Other specified diabetes mellitus
0.000 0.433 0.566
E16.1 Other hypoglycaemia
0.000 0.438 0.562
K90 Intestinal malabsorption
0.000 0.473 0.527
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.479 0.520
E63 Other nutritional deficiencies
0.000 0.479 0.520
E56 Other vitamin deficiencies
0.000 0.479 0.520
E51 Thiamine deficiency
0.000 0.479 0.520
E50 Vitamin A deficiency
0.000 0.479 0.520
E60 Dietary zinc deficiency
0.000 0.479 0.520
E59 Dietary selenium deficiency
0.000 0.479 0.520
E58 Dietary calcium deficiency
0.000 0.479 0.520
E54 Ascorbic acid deficiency
0.000 0.479 0.520
E52 Niacin deficiency [pellagra]
0.000 0.479 0.520
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.492 0.507
E12.8 With unspecified complications
0.000 0.492 0.507
E12.7 With multiple complications
0.000 0.492 0.507
E12.6 With other specified complications
0.000 0.492 0.507
E12.5 With peripheral circulatory complications
0.000 0.492 0.507
E12.4 With neurological complications
0.000 0.492 0.507
E12.3 With ophthalmic complications
0.000 0.492 0.507
E12.2 With renal complications
0.000 0.492 0.507
E12.1 With ketoacidosis
0.000 0.492 0.507
E12.0 With coma
0.000 0.492 0.507
E53 Deficiency of other B group vitamins
0.000 0.497 0.503
E40-E46 Malnutrition
0.001 0.499 0.500
E61 Deficiency of other nutrient elements
0.000 0.506 0.494
E07.8 Other specified disorders of thyroid
0.000 0.531 0.468
E55.9 Vitamin D deficiency, unspecified
0.000 0.537 0.463
E14 Unspecified diabetes mellitus
0.000 0.555 0.445
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.561 0.439
E67 Other hyperalimentation
0.000 0.578 0.422
E68 Sequelae of hyperalimentation
0.000 0.578 0.422
K90.9 Intestinal malabsorption, unspecified
0.000 0.579 0.421
M07 Psoriatic and enteropathic arthropathies
0.421 0.579 0.000
E55.0 Rickets, active
0.000 0.589 0.411
E13.8 With unspecified complications
0.000 0.594 0.406
E13.7 With multiple complications
0.000 0.594 0.406
E13.6 With other specified complications
0.000 0.594 0.406
E13.5 With peripheral circulatory complications
0.000 0.594 0.406
E13.4 With neurological complications
0.000 0.594 0.406
E13.3 With ophthalmic complications
0.000 0.594 0.406
E13.2 With renal complications
0.000 0.594 0.406
E13.1 With ketoacidosis
0.000 0.594 0.406
E13.0 With coma
0.000 0.594 0.406
E04 Other non-toxic goitre
0.000 0.598 0.402
E66 Obesity
0.000 0.605 0.395
E14.3 With ophthalmic complications
0.000 0.613 0.387
E53.9 Vitamin B deficiency, unspecified
0.000 0.618 0.382
K90.3 Pancreatic steatorrhoea
0.000 0.622 0.378
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.622 0.378
K90.1 Tropical sprue
0.000 0.622 0.378
E66.8 Other obesity
0.000 0.624 0.376
E50.9 Vitamin A deficiency, unspecified
0.000 0.627 0.373
E50.8 Other manifestations of vitamin A deficiency
0.000 0.627 0.373
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.627 0.373
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.627 0.373
E50.5 Vitamin A deficiency with night blindness
0.000 0.627 0.373
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.627 0.373
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.627 0.373
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.627 0.373
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.627 0.373
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.627 0.373
E51.9 Thiamine deficiency, unspecified
0.000 0.627 0.373
E51.8 Other manifestations of thiamine deficiency
0.000 0.627 0.373
E51.2 Wernicke's encephalopathy
0.000 0.627 0.373
E51.1 Beriberi
0.000 0.627 0.373
E56.9 Vitamin deficiency, unspecified
0.000 0.627 0.373
E56.8 Deficiency of other vitamins
0.000 0.627 0.373
E56.1 Deficiency of vitamin K
0.000 0.627 0.373
E56.0 Deficiency of vitamin E
0.000 0.627 0.373
E63.9 Nutritional deficiency, unspecified
0.000 0.627 0.373
E63.8 Other specified nutritional deficiencies
0.000 0.627 0.373
E63.1 Imbalance of constituents of food intake
0.000 0.627 0.373
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.627 0.373
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.627 0.373
E64.8 Sequelae of other nutritional deficiencies
0.000 0.627 0.373
E64.3 Sequelae of rickets
0.000 0.627 0.373
E64.2 Sequelae of vitamin C deficiency
0.000 0.627 0.373
E64.1 Sequelae of vitamin A deficiency
0.000 0.627 0.373
E64.0 Sequelae of protein-energy malnutrition
0.000 0.627 0.373
E53.1 Pyridoxine deficiency
0.000 0.639 0.361
E53.0 Riboflavin deficiency
0.000 0.639 0.361
E61.2 Magnesium deficiency
0.000 0.640 0.360
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.641 0.358
E45 Retarded development following protein-energy malnutrition
0.001 0.641 0.358
E43 Unspecified severe protein-energy malnutrition
0.001 0.641 0.358
E42 Marasmic kwashiorkor
0.001 0.641 0.358
E41 Nutritional marasmus
0.001 0.641 0.358
E40 Kwashiorkor
0.001 0.641 0.358
E61.9 Deficiency of nutrient element, unspecified
0.000 0.646 0.354
E61.8 Deficiency of other specified nutrient elements
0.000 0.646 0.354
E61.7 Deficiency of multiple nutrient elements
0.000 0.646 0.354
E61.6 Vanadium deficiency
0.000 0.646 0.354
E61.5 Molybdenum deficiency
0.000 0.646 0.354
E61.4 Chromium deficiency
0.000 0.646 0.354
E61.3 Manganese deficiency
0.000 0.646 0.354
E61.0 Copper deficiency
0.000 0.646 0.354
E65 Localised adiposity
0.000 0.657 0.342
E61.1 Iron deficiency
0.000 0.679 0.321
E14.7 With multiple complications
0.000 0.681 0.319
E14.6 With other specified complications
0.000 0.681 0.319
E14.2 Withrenal complications
0.000 0.681 0.319
E14.0 With coma
0.000 0.681 0.319
E04.9 Non-toxic goitre, unspecified
0.000 0.683 0.317
E53.8 Deficiency of other specified B group vitamins
0.000 0.684 0.316
E14.1 With ketoacidosis
0.000 0.688 0.312
E14.8 With unspecified complications
0.000 0.696 0.304
E67.8 Other specified hyperalimentation
0.000 0.697 0.303
E67.3 Hypervitaminosis D
0.000 0.697 0.303
E67.2 Megavitamin-B6 syndrome
0.000 0.697 0.303
E67.1 Hypercarotenaemia
0.000 0.697 0.303
E67.0 Hypervitaminosis A
0.000 0.697 0.303
M07.6 Other enteropathic arthropathies
0.302 0.698 0.000
M07.5 Arthropathy in ulcerative colitis
0.302 0.698 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.302 0.698 0.000
M07.2 Psoriatic spondylitis
0.302 0.698 0.000
M07.1 Arthritis mutilans
0.302 0.698 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.302 0.698 0.000
E04.8 Other specified non-toxic goitre
0.000 0.712 0.288
E14.5 With peripheral circulatory complications
0.000 0.714 0.286
E66.1 Drug-induced obesity
0.000 0.716 0.284
K90.8 Other intestinal malabsorption
0.001 0.733 0.266
E13.9 Without complications
0.000 0.735 0.265
E44.1 Mild protein-energy malnutrition
0.001 0.742 0.257
E44.0 Moderate protein-energy malnutrition
0.001 0.742 0.257
E14.4 With neurological complications
0.000 0.744 0.256
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.757 0.243
E04.0 Non-toxic diffuse goitre
0.000 0.757 0.243
E20-E35 Disorders of other endocrine glands
0.000 0.776 0.224
L40-L45 Papulosquamous disorders
0.221 0.778 0.000
E66.0 Obesity due to excess calories
0.000 0.780 0.219
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.217 0.783 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.217 0.783 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.217 0.783 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.217 0.783 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.217 0.783 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.217 0.783 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.217 0.783 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.217 0.783 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.217 0.783 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.217 0.783 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.217 0.783 0.000
M07.18 Arthritis mutilans (Other)
0.217 0.783 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.217 0.783 0.000
M07.16 Arthritis mutilans (Lower leg)
0.217 0.783 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.217 0.783 0.000
M07.14 Arthritis mutilans (Hand)
0.217 0.783 0.000
M07.13 Arthritis mutilans (Forearm)
0.217 0.783 0.000
M07.12 Arthritis mutilans (Upper arm)
0.217 0.783 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.217 0.783 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.217 0.783 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.217 0.783 0.000
M07.28 Psoriatic spondylitis (Other)
0.217 0.783 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.217 0.783 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.217 0.783 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.217 0.783 0.000
M07.24 Psoriatic spondylitis (Hand)
0.217 0.783 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.217 0.783 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.217 0.783 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.217 0.783 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.217 0.783 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.217 0.783 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.217 0.783 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.217 0.783 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.217 0.783 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.217 0.783 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.217 0.783 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.217 0.783 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.217 0.783 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.217 0.783 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.217 0.783 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.217 0.783 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.217 0.783 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.217 0.783 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.217 0.783 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.217 0.783 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.217 0.783 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.217 0.783 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.217 0.783 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.217 0.783 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.217 0.783 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.217 0.783 0.000
M07.68 Other enteropathic arthropathies (Other)
0.217 0.783 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.217 0.783 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.217 0.783 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.217 0.783 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.217 0.783 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.217 0.783 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.217 0.783 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.217 0.783 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.217 0.783 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.796 0.204
E27 Other disorders of adrenal gland
0.000 0.802 0.198
E27.1 Primary adrenocortical insufficiency
0.000 0.806 0.194
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.000 0.822 0.178
E04.1 Non-toxic single thyroid nodule
0.000 0.835 0.165
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.839 0.161
E32 Diseases of thymus
0.000 0.839 0.161
E31 Polyglandular dysfunction
0.000 0.839 0.161
E30 Disorders of puberty, not elsewhere classified
0.000 0.839 0.161
E25 Adrenogenital disorders
0.000 0.839 0.161
L44 Other papulosquamous disorders
0.159 0.841 0.000
L41 Parapsoriasis
0.159 0.841 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.159 0.841 0.000
E34 Other endocrine disorders
0.000 0.844 0.156
L42 Pityriasis rosea
0.155 0.845 0.000
E46 Unspecified protein-energy malnutrition
0.002 0.848 0.150
E27.8 Other specified disorders of adrenal gland
0.000 0.849 0.151
E20 Hypoparathyroidism
0.000 0.849 0.151
E29 Testicular dysfunction
0.000 0.850 0.150
E26 Hyperaldosteronism
0.000 0.856 0.144
E27.5 Adrenomedullary hyperfunction
0.000 0.858 0.142
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.858 0.142
E27.0 Other adrenocortical overactivity
0.000 0.858 0.142
E22 Hyperfunction of pituitary gland
0.000 0.859 0.141
E28 Ovarian dysfunction
0.000 0.860 0.140
E24 Cushing's syndrome
0.000 0.864 0.136
E27.2 Addisonian crisis
0.000 0.868 0.132
E34.0 Carcinoid syndrome
0.000 0.880 0.120
E34.9 Endocrine disorder, unspecified
0.000 0.883 0.117
E25.9 Adrenogenital disorder, unspecified
0.000 0.884 0.116
E25.8 Other adrenogenital disorders
0.000 0.884 0.116
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.884 0.116
E30.9 Disorder of puberty, unspecified
0.000 0.884 0.116
E30.8 Other disorders of puberty
0.000 0.884 0.116
E30.1 Precocious puberty
0.000 0.884 0.116
E30.0 Delayed puberty
0.000 0.884 0.116
E31.9 Polyglandular dysfunction, unspecified
0.000 0.884 0.116
E31.8 Other polyglandular dysfunction
0.000 0.884 0.116
E31.1 Polyglandular hyperfunction
0.000 0.884 0.116
E31.0 Autoimmune polyglandular failure
0.000 0.884 0.116
E32.9 Disease of thymus, unspecified
0.000 0.884 0.116
E32.8 Other diseases of thymus
0.000 0.884 0.116
E32.1 Abscess of thymus
0.000 0.884 0.116
E32.0 Persistent hyperplasia of thymus
0.000 0.884 0.116
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.884 0.116
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.884 0.116
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.884 0.116
L41.9 Parapsoriasis, unspecified
0.114 0.886 0.000
L41.8 Other parapsoriasis
0.114 0.886 0.000
L41.5 Retiform parapsoriasis
0.114 0.886 0.000
L41.4 Large plaque parapsoriasis
0.114 0.886 0.000
L41.3 Small plaque parapsoriasis
0.114 0.886 0.000
L41.2 Lymphomatoid papulosis
0.114 0.886 0.000
L41.1 Pityriasis lichenoides chronica
0.114 0.886 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.114 0.886 0.000
L44.9 Papulosquamous disorder, unspecified
0.114 0.886 0.000
L44.8 Other specified papulosquamous disorders
0.114 0.886 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.114 0.886 0.000
L44.3 Lichen ruber moniliformis
0.114 0.886 0.000
L44.2 Lichen striatus
0.114 0.886 0.000
L44.1 Lichen nitidus
0.114 0.886 0.000
L44.0 Pityriasis rubra pilaris
0.114 0.886 0.000
E34.5 Androgen resistance syndrome
0.000 0.888 0.112
E34.4 Constitutional tall stature
0.000 0.888 0.112
E34.3 Short stature, not elsewhere classified
0.000 0.888 0.112
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.888 0.112
E34.1 Other hypersecretion of intestinal hormones
0.000 0.888 0.112
E22.1 Hyperprolactinaemia
0.000 0.889 0.111
E20.8 Other hypoparathyroidism
0.000 0.891 0.108
E20.1 Pseudohypoparathyroidism
0.000 0.891 0.108
E20.0 Idiopathic hypoparathyroidism
0.000 0.891 0.108
E29.9 Testicular dysfunction, unspecified
0.000 0.892 0.107
E29.8 Other testicular dysfunction
0.000 0.892 0.107
E29.0 Testicular hyperfunction
0.000 0.892 0.107
E26.9 Hyperaldosteronism, unspecified
0.000 0.896 0.104
E26.8 Other hyperaldosteronism
0.000 0.896 0.104
E26.1 Secondary hyperaldosteronism
0.000 0.896 0.104
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.899 0.101
E22.8 Other hyperfunction of pituitary gland
0.000 0.899 0.101
E28.3 Primary ovarian failure
0.000 0.899 0.101
E28.9 Ovarian dysfunction, unspecified
0.000 0.899 0.101
E28.8 Other ovarian dysfunction
0.000 0.899 0.101
E28.1 Androgen excess
0.000 0.899 0.101
E28.0 Oestrogen excess
0.000 0.899 0.101
E20.9 Hypoparathyroidism, unspecified
0.000 0.902 0.098
E24.2 Drug-induced Cushing's syndrome
0.000 0.902 0.098
E24.8 Other Cushing's syndrome
0.000 0.902 0.097
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.902 0.097
E24.3 Ectopic ACTH syndrome
0.000 0.902 0.097
E24.1 Nelson's syndrome
0.000 0.902 0.097
E29.1 Testicular hypofunction
0.000 0.904 0.096
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.904 0.096
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.906 0.094
E22.0 Acromegaly and pituitary gigantism
0.000 0.907 0.093
E24.0 Pituitary-dependent Cushing's disease
0.000 0.913 0.087
E26.0 Primary hyperaldosteronism
0.000 0.913 0.087
E27.9 Disorder of adrenal gland, unspecified
0.001 0.913 0.086
E34.8 Other specified endocrine disorders
0.000 0.914 0.086
E23 Hypofunction and other disorders of pituitary gland
0.000 0.915 0.085
E24.9 Cushing's syndrome, unspecified
0.000 0.915 0.084
E28.2 Polycystic ovarian syndrome
0.000 0.920 0.079
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.925 0.075
L43 Lichen planus
0.072 0.927 0.001
E21.4 Other specified disorders of parathyroid gland
0.000 0.931 0.069
E21.2 Other hyperparathyroidism
0.000 0.931 0.069
K90-K93 Other diseases of the digestive system
0.000 0.931 0.069
E21.3 Hyperparathyroidism, unspecified
0.000 0.933 0.067
E14.9 Without complications
0.000 0.933 0.067
M35.0 Sicca syndrome [Sjogren]
0.000 0.938 0.062
E21.0 Primary hyperparathyroidism
0.000 0.938 0.061
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.939 0.061
E23.1 Drug-induced hypopituitarism
0.000 0.939 0.061
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.060 0.940 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.059 0.941 0.000
E23.0 Hypopituitarism
0.000 0.943 0.057
T36-T50 Poisoning by drugs, medicaments and biological substances
0.056 0.944 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.056 0.944 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.054 0.946 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.947 0.053
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.947 0.053
L43.3 Subacute (active) lichen planus
0.052 0.947 0.001
L43.2 Lichenoid drug reaction
0.052 0.947 0.001
L43.1 Bullous lichen planus
0.052 0.947 0.001
L43.0 Hypertrophic lichen planus
0.052 0.947 0.001
E23.2 Diabetes insipidus
0.000 0.947 0.052
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.950 0.049
E23.6 Other disorders of pituitary gland
0.000 0.950 0.049
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.049 0.951 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.049 0.951 0.000
T43.2 Other and unspecified antidepressants
0.049 0.951 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.047 0.953 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.046 0.954 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.045 0.955 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.045 0.955 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.045 0.955 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.045 0.955 0.000
T43.6 Psychostimulants with abuse potential
0.044 0.956 0.000
E23.7 Disorder of pituitary gland, unspecified
0.001 0.956 0.043
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.043 0.957 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.043 0.957 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.043 0.957 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.043 0.957 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.043 0.957 0.000
T44.0 Anticholinesterase agents
0.043 0.957 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.043 0.957 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.043 0.957 0.000
T36 Poisoning by systemic antibiotics
0.043 0.957 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.042 0.958 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.959 0.041
E66.9 Obesity, unspecified
0.000 0.959 0.041
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.040 0.960 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.040 0.960 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.040 0.960 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.040 0.960 0.000
K91.4 Colostomy and enterostomy malfunction
0.000 0.960 0.040
R41.0 Disorientation, unspecified
0.000 0.960 0.040
T47.4 Other laxatives
0.039 0.961 0.000
L43.8 Other lichen planus
0.037 0.961 0.001
T43.9 Psychotropic drug, unspecified
0.039 0.961 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.039 0.961 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.039 0.961 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.036 0.964 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.036 0.964 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.964 0.036
K93.1 Megacolon in Chagas' disease
0.000 0.964 0.036
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.964 0.036
T43.3 Phenothiazine antipsychotics and neuroleptics
0.036 0.964 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.036 0.964 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.036 0.964 0.000
T47.7 Emetics
0.036 0.964 0.000
T47.6 Antidiarrhoeal drugs
0.036 0.964 0.000
T47.5 Digestants
0.036 0.964 0.000
T47.3 Saline and osmotic laxatives
0.036 0.964 0.000
T47.2 Stimulant laxatives
0.036 0.964 0.000
T47.0 Histamine H(2)-receptor antagonists
0.036 0.964 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.036 0.964 0.000
T50.8 Diagnostic agents
0.035 0.964 0.000
T50.7 Analeptics and opioid receptor antagonists
0.035 0.964 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.035 0.964 0.000
T50.5 Appetite depressants
0.035 0.964 0.000
T50.4 Drugs affecting uric acid metabolism
0.035 0.964 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.035 0.964 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.035 0.964 0.000
T50.1 Loop [high-ceiling] diuretics
0.035 0.964 0.000
T50.0 Mineralocorticoids and their antagonists
0.035 0.964 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.035 0.964 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.035 0.965 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.034 0.966 0.000
T38.1 Thyroid hormones and substitutes
0.034 0.966 0.000
M05-M14 Inflammatory polyarthropathies
0.034 0.966 0.000
T36.0 Penicillins
0.033 0.967 0.000
K91.1 Postgastric surgery syndromes
0.000 0.967 0.033
T38.9 Other and unspecified hormone antagonists
0.032 0.968 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.032 0.968 0.000
T38.7 Androgens and anabolic congeners
0.032 0.968 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.032 0.968 0.000
T38.5 Other oestrogens and progestogens
0.032 0.968 0.000
T38.4 Oral contraceptives
0.032 0.968 0.000
T38.2 Antithyroid drugs
0.032 0.968 0.000
T38.0 Glucocorticoids and synthetic analogues
0.032 0.968 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.032 0.968 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.031 0.969 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.031 0.969 0.000
T42.3 Barbiturates
0.031 0.969 0.000
T42.2 Succinimides and oxazolidinediones
0.031 0.969 0.000
T36.9 Systemic antibiotic, unspecified
0.031 0.969 0.000
T36.8 Other systemic antibiotics
0.031 0.969 0.000
T36.7 Antifungal antibiotics, systemically used
0.031 0.969 0.000
T36.6 Rifamycins
0.031 0.969 0.000
T36.5 Aminoglycosides
0.031 0.969 0.000
T36.4 Tetracyclines
0.031 0.969 0.000
T36.3 Macrolides
0.031 0.969 0.000
T36.2 Chloramphenicol group
0.031 0.969 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.031 0.969 0.000
T42.0 Hydantoin derivatives
0.030 0.969 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.030 0.970 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.030 0.970 0.000
T46.7 Peripheral vasodilators
0.030 0.970 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.030 0.970 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.030 0.970 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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