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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6457327
log Bayes Factor = 97.5341
Chromosome 6   position 31,074,030  (GRCh37) Explore rs6457327 on Ensembl!
Variant rs6457327 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
C83.3 Large cell (diffuse)
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.003 0.997
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.003 0.997
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.004 0.996
C85.1 B-cell lymphoma, unspecified
0.000 0.011 0.989
C61 Malignant neoplasm of prostate
0.988 0.012 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.015 0.985
C81 Hodgkin's disease
0.000 0.018 0.982
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.021 0.979
E07 Other disorders of thyroid
0.000 0.042 0.958
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.044 0.956
C81.9 Hodgkin's disease, unspecified
0.000 0.044 0.956
E07.9 Disorder of thyroid, unspecified
0.000 0.074 0.926
L40.0 Psoriasis vulgaris
0.000 0.094 0.906
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.136 0.864
L40.1 Generalised pustular psoriasis
0.000 0.152 0.848
C82.2 Large cell, follicular
0.000 0.157 0.843
L40.8 Other psoriasis
0.000 0.158 0.842
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.167 0.833
E03.8 Other specified hypothyroidism
0.000 0.180 0.820
C81.2 Mixed cellularity
0.000 0.180 0.820
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.180 0.820
C83.7 Burkitt's tumour
0.000 0.193 0.807
C82.3 Follicular lymphoma grade IIIa
0.000 0.197 0.803
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.213 0.787
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.226 0.774
C81.1 Nodular sclerosis
0.000 0.234 0.766
C81.0 Lymphocytic predominance
0.000 0.248 0.752
L40.4 Guttate psoriasis
0.000 0.261 0.739
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.271 0.729
C86 Other specified types of T/NK-cell lymphoma
0.000 0.281 0.718
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
C83.6 Undifferentiated (diffuse)
0.000 0.285 0.715
C83.5 Lymphoblastic (diffuse)
0.000 0.285 0.715
C83.4 Immunoblastic (diffuse)
0.000 0.285 0.715
C83.2 Mixed small and large cell (diffuse)
0.000 0.285 0.715
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.285 0.715
C85.0 Lymphosarcoma
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.286 0.714
E07.8 Other specified disorders of thyroid
0.000 0.291 0.709
C82.6 Cutaneous follicle centre lymphoma
0.000 0.294 0.706
C82.5 Diffuse follicle centre lymphoma
0.000 0.294 0.706
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.296 0.704
C81.3 Lymphocytic depletion
0.000 0.296 0.704
E07.1 Dyshormogenetic goitre
0.000 0.313 0.687
E07.0 Hypersecretion of calcitonin
0.000 0.313 0.687
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.325 0.675
C94 Other leukaemias of specified cell type
0.000 0.326 0.673
C81.7 Other Hodgkin's disease
0.000 0.327 0.673
C82.4 Follicular lymphoma grade IIIb
0.000 0.332 0.667
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.333 0.667
C82.0 Small cleaved cell, follicular
0.000 0.336 0.664
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.342 0.658
C83.1 Small cleaved cell (diffuse)
0.000 0.357 0.643
C84.5 Other and unspecified T-cell lymphomas
0.000 0.357 0.643
C93 Monocytic leukaemia
0.000 0.359 0.641
E06 Thyroiditis
0.000 0.379 0.621
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.383 0.617
C88 Malignant immunoproliferative diseases
0.000 0.406 0.594
C84.0 Mycosis fungoides
0.000 0.406 0.593
E03.1 Congenital hypothyroidism without goitre
0.000 0.414 0.586
K90 Intestinal malabsorption
0.000 0.422 0.578
L40.3 Pustulosis palmaris et plantaris
0.000 0.424 0.576
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.435 0.564
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.435 0.564
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.435 0.564
C84.3 Lymphoepithelioid lymphoma
0.000 0.435 0.564
C84.2 T-zone lymphoma
0.000 0.435 0.564
C84.1 Sezary's diease
0.000 0.435 0.564
C95 Leukaemia of unspecified cell type
0.000 0.450 0.550
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.455 0.544
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.456 0.544
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.460 0.539
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.481 0.519
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.485 0.515
C86.4 Blastic NK-cell lymphoma
0.000 0.485 0.515
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.485 0.515
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.485 0.515
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.485 0.515
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.487 0.513
C96.8 Histiocytic sarcoma
0.000 0.487 0.513
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.487 0.513
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.487 0.513
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.487 0.513
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.487 0.513
C96.3 True histiocytic lymphoma
0.000 0.487 0.513
C96.2 Malignant mast cell tumour
0.000 0.487 0.513
C96.1 Malignant histiocytosis
0.000 0.487 0.513
C96.0 Letterer-Siwe disease
0.000 0.487 0.513
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.487 0.513
E06.3 Autoimmune thyroiditis
0.000 0.509 0.491
E05.8 Other thyrotoxicosis
0.001 0.510 0.490
C94.7 Other specified leukaemias
0.000 0.517 0.483
C94.5 Acute myelofibrosis
0.000 0.517 0.483
C94.4 Acute panmyelosis
0.000 0.517 0.483
C94.3 Mast cell leukaemia
0.000 0.517 0.483
C94.2 Acute megakaryoblastic leukaemia
0.000 0.517 0.483
C94.1 Chronic erythraemia
0.000 0.517 0.483
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.517 0.483
C93.9 Monocytic leukaemia, unspecified
0.000 0.540 0.460
C93.7 Other monocytic leukaemia
0.000 0.540 0.460
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.540 0.460
C93.2 Subacute monocytic leukaemia
0.000 0.540 0.460
C93.0 Acute monocytic leukaemia
0.000 0.540 0.460
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.544 0.455
E06.5 Other chronic thyroiditis
0.000 0.555 0.445
E06.4 Drug-induced thyroiditis
0.000 0.555 0.445
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.555 0.445
E06.0 Acute thyroiditis
0.000 0.555 0.445
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.558 0.441
C84.4 Peripheral T-cell lymphoma
0.000 0.561 0.439
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.574 0.426
C88.7 Other malignant immunoproliferative diseases
0.000 0.574 0.426
C88.3 Immunoproliferative small intestinal disease
0.000 0.574 0.426
C88.2 Gamma heavy chain disease
0.000 0.574 0.426
C88.1 Alpha heavy chain disease
0.000 0.574 0.426
K90.3 Pancreatic steatorrhoea
0.000 0.585 0.414
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.585 0.414
K90.1 Tropical sprue
0.000 0.585 0.414
L40-L45 Papulosquamous disorders
0.000 0.593 0.407
K90.8 Other intestinal malabsorption
0.000 0.602 0.398
E06.1 Subacute thyroiditis
0.000 0.604 0.396
C95.7 Other leukaemia of unspecified cell type
0.000 0.605 0.394
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.605 0.394
C93.1 Chronic monocytic leukaemia
0.000 0.614 0.386
C95.9 Leukaemia, unspecified
0.000 0.622 0.378
C91 Lymphoid leukaemia
0.000 0.628 0.372
K90.9 Intestinal malabsorption, unspecified
0.000 0.629 0.371
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.637 0.362
C92 Myeloid leukaemia
0.000 0.645 0.355
C60-C63 Malignant neoplasms of male genital organs
0.349 0.651 0.000
C91.9 Lymphoid leukaemia, unspecified
0.000 0.660 0.340
E06.9 Thyroiditis, unspecified
0.000 0.665 0.334
L43 Lichen planus
0.000 0.686 0.314
C95.0 Acute leukaemia of unspecified cell type
0.001 0.691 0.309
C92.1 Chronic myeloid leukaemia
0.000 0.692 0.308
L44 Other papulosquamous disorders
0.000 0.708 0.292
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.708 0.292
L42 Pityriasis rosea
0.000 0.711 0.289
C90 Multiple myeloma and malignant plasma cell neoplasms
0.003 0.718 0.279
C60 Malignant neoplasm of penis
0.272 0.728 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.733 0.267
C91.7 Other lymphoid leukaemia
0.000 0.733 0.267
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.733 0.267
C91.3 Prolymphocytic leukaemia
0.000 0.733 0.267
C91.2 Subacute lymphocytic leukaemia
0.000 0.733 0.267
C83.0 Small cell (diffuse)
0.001 0.736 0.263
L41 Parapsoriasis
0.000 0.738 0.262
L43.9 Lichen planus, unspecified
0.000 0.744 0.256
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.745 0.254
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.745 0.254
C92.3 Myeloid sarcoma
0.000 0.745 0.254
C92.2 Subacute myeloid leukaemia
0.000 0.745 0.254
C63 Malignant neoplasm of other and unspecified male genital organs
0.254 0.746 0.000
C91.5 Adult T-cell leukaemia
0.000 0.748 0.252
C88.0 Waldenstrom's macroglobulinaemia
0.001 0.755 0.244
C92.5 Acute myelomonocytic leukaemia
0.000 0.770 0.230
C92.9 Myeloid leukaemia, unspecified
0.000 0.772 0.228
L43.3 Subacute (active) lichen planus
0.000 0.775 0.225
L43.2 Lichenoid drug reaction
0.000 0.775 0.225
L43.1 Bullous lichen planus
0.000 0.775 0.225
L43.0 Hypertrophic lichen planus
0.000 0.775 0.225
C60.9 Penis, unspecified
0.213 0.787 0.000
L43.8 Other lichen planus
0.000 0.788 0.212
L44.9 Papulosquamous disorder, unspecified
0.000 0.790 0.209
L44.8 Other specified papulosquamous disorders
0.000 0.790 0.209
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.790 0.209
L44.3 Lichen ruber moniliformis
0.000 0.790 0.209
L44.2 Lichen striatus
0.000 0.790 0.209
L44.1 Lichen nitidus
0.000 0.790 0.209
L44.0 Pityriasis rubra pilaris
0.000 0.790 0.209
C90.1 Plasma cell leukaemia
0.002 0.791 0.207
C90.3 Solitary plasmacytoma
0.002 0.795 0.203
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.203 0.797 0.000
C60.1 Glans penis
0.201 0.799 0.000
C60.0 Prepuce
0.196 0.804 0.000
C60.8 Overlapping lesion of penis
0.195 0.804 0.000
C60.2 Body of penis
0.195 0.804 0.000
C92.4 Acute promyelocytic leukaemia
0.001 0.806 0.194
C92.7 Other myeloid leukaemia
0.001 0.810 0.189
L41.9 Parapsoriasis, unspecified
0.000 0.812 0.188
L41.8 Other parapsoriasis
0.000 0.812 0.188
L41.5 Retiform parapsoriasis
0.000 0.812 0.188
L41.4 Large plaque parapsoriasis
0.000 0.812 0.188
L41.3 Small plaque parapsoriasis
0.000 0.812 0.188
L41.2 Lymphomatoid papulosis
0.000 0.812 0.188
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.812 0.188
C63.2 Scrotum
0.186 0.814 0.000
C63.9 Male genital organ, unspecified
0.182 0.818 0.000
C63.8 Overlapping lesion of male genital organs
0.182 0.818 0.000
C63.7 Other specified male genital organs
0.182 0.818 0.000
C63.1 Spermatic cord
0.182 0.818 0.000
C63.0 Epididymis
0.182 0.818 0.000
C62 Malignant neoplasm of testis
0.176 0.824 0.000
C91.4 Hairy-cell leukaemia
0.001 0.826 0.173
L41.1 Pityriasis lichenoides chronica
0.000 0.842 0.157
C91.0 Acute lymphoblastic leukaemia
0.001 0.852 0.147
C62.0 Undescended testis
0.126 0.873 0.000
C62.1 Descended testis
0.126 0.874 0.000
C92.0 Acute myeloid leukaemia
0.000 0.881 0.119
C90.2 Plasmacytoma, extramedullary
0.003 0.893 0.104
I83 Varicose veins of lower extremities
0.097 0.903 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.088 0.911 0.000
E83 Disorders of mineral metabolism
0.080 0.919 0.001
E04 Other non-toxic goitre
0.000 0.924 0.076
Z85.4 Personal history of malignant neoplasm of genital organs
0.073 0.927 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.072 0.928 0.000
K60.2 Anal fissure, unspecified
0.000 0.938 0.062
E83.9 Disorder of mineral metabolism, unspecified
0.061 0.938 0.000
C91.1 Chronic lymphocytic leukaemia
0.000 0.940 0.059
E83.8 Other disorders of mineral metabolism
0.058 0.942 0.001
E83.2 Disorders of zinc metabolism
0.058 0.942 0.001
E83.0 Disorders of copper metabolism
0.058 0.942 0.001
K60 Fissure and fistula of anal and rectal regions
0.000 0.944 0.056
E04.8 Other specified non-toxic goitre
0.000 0.945 0.055
C62.9 Testis, unspecified
0.053 0.946 0.000
K60.3 Anal fistula
0.000 0.947 0.053
E04.0 Non-toxic diffuse goitre
0.000 0.948 0.052
K60.5 Anorectal fistula
0.000 0.948 0.052
E83.3 Disorders of phosphorus metabolism
0.050 0.949 0.000
K60.0 Acute anal fissure
0.000 0.954 0.046
Z51.3 Blood transfusion without reported diagnosis
0.000 0.960 0.040
K60.1 Chronic anal fissure
0.000 0.961 0.039
K60.4 Rectal fistula
0.000 0.962 0.038
K90-K93 Other diseases of the digestive system
0.000 0.963 0.037
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.973 0.027
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.976 0.024
E83.4 Disorders of magnesium metabolism
0.023 0.976 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.021 0.979 0.000
E40-E46 Malnutrition
0.000 0.980 0.020
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.981 0.019
K93.1 Megacolon in Chagas' disease
0.000 0.981 0.019
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.981 0.019
E20-E35 Disorders of other endocrine glands
0.000 0.981 0.019
N05.2 Diffuse membranous glomerulonephritis
0.000 0.982 0.018
E24 Cushing's syndrome
0.000 0.982 0.018
C90.0 Multiple myeloma
0.004 0.982 0.014
I83.1 Varicose veins of lower extremities with inflammation
0.018 0.982 0.000
N05.9 Unspecified
0.000 0.982 0.018
E23 Hypofunction and other disorders of pituitary gland
0.000 0.982 0.018
N05 Unspecified nephritic syndrome
0.000 0.982 0.018
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.017 0.983 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.983 0.017
E46 Unspecified protein-energy malnutrition
0.000 0.983 0.017
E28 Ovarian dysfunction
0.000 0.983 0.017
E24.0 Pituitary-dependent Cushing's disease
0.000 0.984 0.016
H00.1 Chalazion
0.016 0.984 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.984 0.016
E24.2 Drug-induced Cushing's syndrome
0.000 0.984 0.016
N05.1 Focal and segmental glomerular lesions
0.000 0.984 0.016
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.984 0.016
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.016 0.984 0.000
E23.2 Diabetes insipidus
0.000 0.984 0.016
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.985 0.015
M07.3 Other psoriatic arthropathies
0.000 0.985 0.015
E28.3 Primary ovarian failure
0.000 0.985 0.015
E24.9 Cushing's syndrome, unspecified
0.000 0.985 0.015
E25 Adrenogenital disorders
0.000 0.985 0.015
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.985 0.015
E23.6 Other disorders of pituitary gland
0.000 0.985 0.015
I80 Phlebitis and thrombophlebitis
0.015 0.985 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.986 0.014
E45 Retarded development following protein-energy malnutrition
0.000 0.986 0.014
E43 Unspecified severe protein-energy malnutrition
0.000 0.986 0.014
E42 Marasmic kwashiorkor
0.000 0.986 0.014
E41 Nutritional marasmus
0.000 0.986 0.014
E40 Kwashiorkor
0.000 0.986 0.014
E21.3 Hyperparathyroidism, unspecified
0.000 0.986 0.014
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.986 0.014
E32 Diseases of thymus
0.000 0.986 0.014
E30 Disorders of puberty, not elsewhere classified
0.000 0.986 0.014
E31 Polyglandular dysfunction
0.000 0.986 0.014
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.987 0.013
E24.3 Ectopic ACTH syndrome
0.000 0.987 0.013
E24.1 Nelson's syndrome
0.000 0.987 0.013
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.987 0.013
E04.1 Non-toxic single thyroid nodule
0.000 0.987 0.013
E26 Hyperaldosteronism
0.000 0.987 0.013
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.987 0.013
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.987 0.013
E23.1 Drug-induced hypopituitarism
0.000 0.987 0.013
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.987 0.013
N05.6 Dense deposit disease
0.000 0.987 0.013
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.987 0.013
N05.0 Minor glomerular abnormality
0.000 0.987 0.013
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.987 0.013
E24.8 Other Cushing's syndrome
0.000 0.987 0.013
E04.2 Non-toxic multinodular goitre
0.000 0.987 0.013
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.987 0.012
E28.9 Ovarian dysfunction, unspecified
0.000 0.988 0.012
E28.8 Other ovarian dysfunction
0.000 0.988 0.012
E28.1 Androgen excess
0.000 0.988 0.012
E28.0 Oestrogen excess
0.000 0.988 0.012
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.988 0.012
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.988 0.012
E28.2 Polycystic ovarian syndrome
0.000 0.988 0.012
N05.8 Other
0.000 0.988 0.012
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.988 0.012
I26 Pulmonary embolism
0.012 0.988 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.989 0.011
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.989 0.011
E21.2 Other hyperparathyroidism
0.000 0.989 0.011
E20 Hypoparathyroidism
0.000 0.989 0.011
E15 Nondiabetic hypoglycaemic coma
0.000 0.989 0.011
M07.38 Other psoriatic arthropathies (Other)
0.000 0.989 0.011
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.989 0.011
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.989 0.011
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.989 0.011
E25.9 Adrenogenital disorder, unspecified
0.000 0.989 0.011
E25.8 Other adrenogenital disorders
0.000 0.989 0.011
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.011 0.989 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.989 0.011
E44.1 Mild protein-energy malnutrition
0.000 0.989 0.010
E44.0 Moderate protein-energy malnutrition
0.000 0.989 0.010
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.011 0.989 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.990 0.010
E30.8 Other disorders of puberty
0.000 0.990 0.010
E30.1 Precocious puberty
0.000 0.990 0.010
E30.0 Delayed puberty
0.000 0.990 0.010
E32.9 Disease of thymus, unspecified
0.000 0.990 0.010
E32.8 Other diseases of thymus
0.000 0.990 0.010
E32.1 Abscess of thymus
0.000 0.990 0.010
E32.0 Persistent hyperplasia of thymus
0.000 0.990 0.010
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.990 0.010
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.990 0.010
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.990 0.010
E31.9 Polyglandular dysfunction, unspecified
0.000 0.990 0.010
E31.8 Other polyglandular dysfunction
0.000 0.990 0.010
E31.1 Polyglandular hyperfunction
0.000 0.990 0.010
E31.0 Autoimmune polyglandular failure
0.000 0.990 0.010
E22 Hyperfunction of pituitary gland
0.000 0.990 0.010
E83.5 Disorders of calcium metabolism
0.010 0.990 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.990 0.010
E26.9 Hyperaldosteronism, unspecified
0.000 0.990 0.010
E26.8 Other hyperaldosteronism
0.000 0.990 0.010
E26.1 Secondary hyperaldosteronism
0.000 0.990 0.010
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.991 0.009
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.009 0.991 0.000
E23.0 Hypopituitarism
0.000 0.991 0.009
E29 Testicular dysfunction
0.000 0.991 0.009
D64.9 Anaemia, unspecified
0.000 0.991 0.009
B02.9 Zoster without complication
0.000 0.991 0.009
E26.0 Primary hyperaldosteronism
0.000 0.991 0.009
E27 Other disorders of adrenal gland
0.000 0.991 0.009
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.009 0.991 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.991 0.009
I82 Other venous embolism and thrombosis
0.009 0.991 0.000
E20.8 Other hypoparathyroidism
0.000 0.992 0.008
E20.1 Pseudohypoparathyroidism
0.000 0.992 0.008
E20.0 Idiopathic hypoparathyroidism
0.000 0.992 0.008
H00 Hordeolum and chalazion
0.008 0.992 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.992 0.008
E27.9 Disorder of adrenal gland, unspecified
0.000 0.992 0.008
E10-E14 Diabetes mellitus
0.000 0.992 0.008
E04.9 Non-toxic goitre, unspecified
0.000 0.992 0.007
E34 Other endocrine disorders
0.001 0.992 0.007
I88 Nonspecific lymphadenitis
0.007 0.993 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.007 0.993 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.993 0.007
E22.8 Other hyperfunction of pituitary gland
0.000 0.993 0.007
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.993 0.007
I82.2 Embolism and thrombosis of vena cava
0.007 0.993 0.000
I85 Oesophageal varices
0.007 0.993 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.993 0.007
I82.3 Embolism and thrombosis of renal vein
0.007 0.993 0.000
E29.8 Other testicular dysfunction
0.000 0.993 0.006
E29.0 Testicular hyperfunction
0.000 0.993 0.006
E27.5 Adrenomedullary hyperfunction
0.000 0.993 0.007
E27.0 Other adrenocortical overactivity
0.000 0.993 0.007
H00.0 Hordeolum and other deep inflammation of eyelid
0.007 0.993 0.000
E50-E64 Other nutritional deficiencies
0.000 0.993 0.007
E78.8 Other disorders of lipoprotein metabolism
0.000 0.993 0.007
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.007 0.993 0.000
I82.0 Budd-Chiari syndrome
0.006 0.993 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.993 0.007
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.993 0.006
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.993 0.006
E16.4 Abnormal secretion of gastrin
0.000 0.993 0.006
E16.3 Increased secretion of glucagon
0.000 0.993 0.006
E16.1 Other hypoglycaemia
0.000 0.993 0.006
I82.1 Thrombophlebitis migrans
0.006 0.993 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.994 0.006
I82.8 Embolism and thrombosis of other specified veins
0.006 0.994 0.000
I85.0 Oesophageal varices with bleeding
0.006 0.994 0.000
E70-E90 Metabolic disorders
0.003 0.994 0.004
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.994 0.006
I47.2 Ventricular tachycardia
0.000 0.994 0.006
E29.9 Testicular dysfunction, unspecified
0.000 0.994 0.006
W10.4 Street and highway
0.006 0.994 0.000
E22.1 Hyperprolactinaemia
0.000 0.994 0.006
E67 Other hyperalimentation
0.000 0.994 0.006
E68 Sequelae of hyperalimentation
0.000 0.994 0.006
E13 Other specified diabetes mellitus
0.000 0.994 0.006
E12 Malnutrition-related diabetes mellitus
0.000 0.994 0.006
B02 Zoster [herpes zoster]
0.000 0.994 0.006
I82.9 Embolism and thrombosis of unspecified vein
0.006 0.994 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.994 0.006
E20.9 Hypoparathyroidism, unspecified
0.000 0.994 0.005
E34.5 Androgen resistance syndrome
0.001 0.994 0.005
E34.4 Constitutional tall stature
0.001 0.994 0.005
E34.3 Short stature, not elsewhere classified
0.001 0.994 0.005
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.994 0.005
E34.1 Other hypersecretion of intestinal hormones
0.001 0.994 0.005
I88.9 Nonspecific lymphadenitis, unspecified
0.005 0.994 0.000
S82.00 Fracture of patella (closed)
0.000 0.994 0.006
E34.8 Other specified endocrine disorders
0.000 0.994 0.005
I88.1 Chronic lymphadenitis, except mesenteric
0.005 0.994 0.000
E27.2 Addisonian crisis
0.000 0.994 0.005
E85 Amyloidosis
0.005 0.994 0.001
B02.3 Zoster ocular disease
0.000 0.994 0.005
I88.8 Other nonspecific lymphadenitis
0.005 0.995 0.000
E78.6 Lipoprotein deficiency
0.000 0.995 0.005
M41.9 Scoliosis, unspecified
0.005 0.995 0.000
E56 Other vitamin deficiencies
0.000 0.995 0.005
E85.9 Amyloidosis, unspecified
0.005 0.995 0.000
E78.4 Other hyperlipidaemia
0.000 0.995 0.005
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.995 0.005
E63 Other nutritional deficiencies
0.000 0.995 0.005
E50 Vitamin A deficiency
0.000 0.995 0.005
E60 Dietary zinc deficiency
0.000 0.995 0.005
E59 Dietary selenium deficiency
0.000 0.995 0.005
E52 Niacin deficiency [pellagra]
0.000 0.995 0.005
I88.0 Nonspecific mesenteric lymphadenitis
0.005 0.995 0.000
E51 Thiamine deficiency
0.000 0.995 0.005
W07.0 Home
0.005 0.995 0.000
E21.0 Primary hyperparathyroidism
0.000 0.995 0.005
E85.3 Secondary systemic amyloidosis
0.005 0.995 0.000
E13.3 With ophthalmic complications
0.000 0.995 0.005
E58 Dietary calcium deficiency
0.000 0.995 0.005
W10 Fall on and from stairs and steps
0.005 0.995 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.995 0.005
M41.96 Scoliosis, unspecified (Lumbar region)
0.005 0.995 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.005 0.995 0.000
E85.4 Organ-limited amyloidosis
0.005 0.995 0.000
E77 Disorders of glycoprotein metabolism
0.002 0.995 0.003
E76 Disorders of glycosaminoglycan metabolism
0.002 0.995 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.002 0.995 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.002 0.995 0.003
E65 Localised adiposity
0.000 0.995 0.005
M41.99 Scoliosis, unspecified (Site unspecified)
0.005 0.995 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.005 0.995 0.000
E72 Other disorders of amino-acid metabolism
0.002 0.995 0.003
S72.30 Fracture of shaft of femur (closed)
0.005 0.995 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.995 0.003
E78.5 Hyperlipidaemia, unspecified
0.000 0.995 0.005
E78.1 Pure hyperglyceridaemia
0.000 0.995 0.005
E79 Disorders of purine and pyrimidine metabolism
0.002 0.995 0.002
E70 Disorders of aromatic amino-acid metabolism
0.002 0.995 0.003
E67.8 Other specified hyperalimentation
0.000 0.995 0.004
E67.3 Hypervitaminosis D
0.000 0.995 0.004
E67.2 Megavitamin-B6 syndrome
0.000 0.995 0.004
E67.1 Hypercarotenaemia
0.000 0.995 0.004
E67.0 Hypervitaminosis A
0.000 0.995 0.004
E84 Cystic fibrosis
0.002 0.995 0.002
E13.8 With unspecified complications
0.000 0.995 0.004
E13.7 With multiple complications
0.000 0.995 0.004
E13.6 With other specified complications
0.000 0.995 0.004
E13.5 With peripheral circulatory complications
0.000 0.995 0.004
E13.4 With neurological complications
0.000 0.995 0.004
E13.2 With renal complications
0.000 0.995 0.004
E13.1 With ketoacidosis
0.000 0.995 0.004
E13.0 With coma
0.000 0.995 0.004
E27.1 Primary adrenocortical insufficiency
0.000 0.995 0.005
E85.8 Other amyloidosis
0.004 0.995 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.005 0.995 0.000
B02.8 Zoster with other complications
0.000 0.995 0.004
E61 Deficiency of other nutrient elements
0.000 0.995 0.004
E78.3 Hyperchylomicronaemia
0.000 0.995 0.004
B02.7 Disseminated zoster
0.000 0.995 0.004
B02.1 Zoster meningitis
0.000 0.995 0.004
B02.0 Zoster encephalitis
0.000 0.995 0.004
E12.9 Without complications
0.000 0.995 0.004
E12.8 With unspecified complications
0.000 0.995 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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