TreeWAS – Variant ID: rs6462411

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G47.3 Sleep apnoea	0.000	0.946	0.054
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.047	0.953	0.000
M51.2 Other specified intervertebral disk displacement	0.037	0.963	0.000
Z30 Contraceptive management	0.025	0.975	0.000
Z30.3 Menstrual extraction	0.024	0.976	0.000
C78.0 Secondary malignant neoplasm of lung	0.022	0.978	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.020	0.980	0.000
Z36 Antenatal screening	0.020	0.980	0.000
Z36.8 Other antenatal screening	0.019	0.981	0.000
Z30.8 Other contraceptive management	0.019	0.981	0.000
Z30.0 General counselling and advice on contraception	0.018	0.981	0.000
Z30.9 Contraceptive management, unspecified	0.018	0.982	0.000
Z30.4 Surveillance of contraceptive drugs	0.018	0.982	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.018	0.982	0.000
Z37 Outcome of delivery	0.018	0.982	0.000
Z37.0 Single live birth	0.017	0.983	0.000
Z63.0 Problems in relationship with spouse or partner	0.017	0.983	0.000
Z36.9 Antenatal screening, unspecified	0.016	0.984	0.000
Z31 Procreative management	0.016	0.984	0.000
Z33 Pregnant state, incidental	0.016	0.984	0.000
Z37.1 Single stillbirth	0.015	0.985	0.000
Z39 Postpartum care and examination	0.015	0.985	0.000
Z36.5 Antenatal screening for isoimmunisation	0.014	0.985	0.000
Z38 Liveborn infants according to place of birth	0.014	0.985	0.000
Z32 Pregnancy examination and test	0.014	0.986	0.000
Z39.1 Care and examination of lactating mother	0.014	0.986	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.014	0.986	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.013	0.986	0.000
Z31.2 In vitro fertilisation	0.013	0.987	0.000
Z37.9 Outcome of delivery unspecified	0.013	0.987	0.000
Z37.7 Other multiple births, all stillborn	0.013	0.987	0.000
Z37.6 Other multiple births, some liveborn	0.013	0.987	0.000
Z37.5 Other multiple births, all liveborn	0.013	0.987	0.000
Z37.4 Twins, both stillborn	0.013	0.987	0.000
Z37.3 Twins, one liveborn and one stillborn	0.013	0.987	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.013	0.987	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.013	0.987	0.000
G47 Sleep disorders	0.000	0.988	0.012
Z31.4 Procreative investigation and testing	0.012	0.988	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.012	0.988	0.000
Z31.9 Procreative management, unspecified	0.012	0.988	0.000
Z31.6 General counselling and advice on procreation	0.012	0.988	0.000
Z31.5 Genetic counselling	0.012	0.988	0.000
Z31.3 Other assisted fertilisation methods	0.012	0.988	0.000
Z31.1 Artifical insemination	0.012	0.988	0.000
Z31.8 Other procreative management	0.012	0.988	0.000
Z32.1 Pregnancy confirmed	0.011	0.989	0.000
M51 Other intervertebral disk disorders	0.011	0.989	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.989	0.011
Z38.8 Other multiple, unspecified as to place of birth	0.010	0.989	0.000
Z38.7 Other multiple, born outside hospital	0.010	0.989	0.000
Z38.6 Other multiple, born in hospital	0.010	0.989	0.000
Z38.5 Twin, unspecified as to place of birth	0.010	0.989	0.000
Z38.4 Twin, born outside hospital	0.010	0.989	0.000
Z38.3 Twin, born in hospital	0.010	0.989	0.000
Z38.2 Singleton, unspecified as to place of birth	0.010	0.989	0.000
Z38.1 Singleton, born outside hospital	0.010	0.989	0.000
Z32.9 Pregnancy confirmed (erroneous code. See Z321)	0.010	0.989	0.000
Z38.0 Singleton, born in hospital	0.010	0.989	0.000
Z63 Other problems related to primary support group, including family circumstances	0.010	0.990	0.000
Z39.2 Routine postpartum follow-up	0.010	0.990	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.009	0.991	0.000
Z63.8 Other specified problems related to primary support group	0.009	0.991	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.009	0.991	0.000
G47.8 Other sleep disorders	0.000	0.991	0.009
Z63.7 Other stressful life events affecting family and household	0.009	0.991	0.000
Z35 Supervision of high-risk pregnancy	0.009	0.991	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.992	0.008
M51.3 Other specified intervertebral disk degeneration	0.008	0.992	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.008	0.992	0.000
N81.3 Complete uterovaginal prolapse	0.008	0.992	0.000
F20.9 Schizophrenia, unspecified	0.008	0.992	0.000
H43.1 Vitreous haemorrhage	0.000	0.992	0.008
G47.4 Narcolepsy and cataplexy	0.000	0.992	0.008
H92.0 Otalgia	0.000	0.992	0.008
N19 Unspecified renal failure	0.008	0.992	0.000
G47.2 Disorders of the sleep-wake schedule	0.000	0.992	0.007
M51.4 Schmorl's nodes	0.008	0.992	0.000
Z63.9 Problem related to primary support group, unspecified	0.007	0.992	0.000
Z63.3 Absence of family member	0.007	0.992	0.000
Z63.2 Inadequate family support	0.007	0.992	0.000
Z63.1 Problems in relationship with parents and in-laws	0.007	0.992	0.000
Z39.0 Care and examination immediately after delivery	0.007	0.993	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.007	0.993	0.000
Z63.6 Dependent relative needing care at home	0.007	0.993	0.000
Y60.0 During surgical operation	0.007	0.993	0.000
Z63.5 Disruption of family by separation and divorce	0.007	0.993	0.000
H93.1 Tinnitus	0.000	0.993	0.007
H92 Otalgia and effusion of ear	0.000	0.993	0.007
M51.9 Intervertebral disk disorder, unspecified	0.007	0.993	0.000
Z34 Supervision of normal pregnancy	0.007	0.993	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.993	0.007
Z37.2 Twins, both liveborn	0.006	0.993	0.000
R41.3 Other amnesia	0.000	0.993	0.007
Z35.9 Supervision of high-risk pregnancy, unspecified	0.006	0.993	0.000
M17.0 Primary gonarthrosis, bilateral	0.000	0.993	0.007
Z35.7 Supervision of high-risk pregnancy due to social problems	0.006	0.994	0.000
Z35.6 Supervision of very young primigravida	0.006	0.994	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.006	0.994	0.000
N30.2 Other chronic cystitis	0.000	0.994	0.006
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.006	0.994	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.006	0.994	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.006	0.994	0.000
H90-H95 Other disorders of ear	0.000	0.994	0.006
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.006	0.994	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.006	0.994	0.000
K08.3 Retained dental root	0.000	0.994	0.006
H90.5 Sensorineural hearing loss, unspecified	0.000	0.994	0.006
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.994	0.006
H90 Conductive and sensorineural hearing loss	0.000	0.994	0.006
M51.8 Other specified intervertebral disk disorders	0.006	0.994	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.994	0.006
F20 Schizophrenia	0.006	0.994	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.994	0.006
Z35.1 Supervision of pregnancy with history of abortive outcome	0.006	0.994	0.000
K85.9 Acute pancreatitis, unspecified	0.006	0.994	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.006	0.994	0.000
H95.1 Other disorders following mastoidectomy	0.000	0.994	0.005
S06.9 Intracranial injury, unspecified	0.005	0.994	0.000
S06.2 Diffuse brain injury	0.005	0.995	0.000
H93.8 Other specified disorders of ear	0.000	0.995	0.005
Z35.4 Supervision of pregnancy with grand multiparity	0.005	0.995	0.000
H93.9 Disorder of ear, unspecified	0.000	0.995	0.005
H90.0 Conductive hearing loss, bilateral	0.000	0.995	0.005
Z35.5 Supervision of elderly primigravida	0.005	0.995	0.000
K85.1 Biliary acute pancreatitis	0.005	0.995	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.005	0.995	0.000
Z34.0 Supervision of normal first pregnancy	0.005	0.995	0.000
H92.2 Otorrhagia	0.000	0.995	0.005
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.995	0.005
S06 Intracranial injury	0.005	0.995	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.005	0.995	0.000
S06.5 Traumatic subdural haemorrhage	0.005	0.995	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.995	0.005
H93.3 Disorders of acoustic nerve	0.000	0.995	0.005
H93.0 Degenerative and vascular disorders of ear	0.000	0.995	0.005
F20.0 Paranoid schizophrenia	0.005	0.995	0.000
Y60.4 During endoscopic examination	0.005	0.995	0.000
K08 Other disorders of teeth and supporting structures	0.000	0.995	0.005
Z35.8 Supervision of other high-risk pregnancies	0.005	0.995	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.995	0.005
S06.6 Traumatic subarachnoid haemorrhage	0.005	0.995	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.995	0.005
F20.5 Residual schizophrenia	0.005	0.995	0.000
K85 Acute pancreatitis	0.005	0.995	0.000
H92.1 Otorrhoea	0.000	0.995	0.005
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.005	0.995	0.000
K26.3 Acute without haemorrhage or perforation	0.004	0.996	0.000
Z63.4 Disappearance and death of family member	0.004	0.996	0.000
F20.8 Other schizophrenia	0.004	0.996	0.000
F20.6 Simple schizophrenia	0.004	0.996	0.000
F20.4 Postschizophrenic depression	0.004	0.996	0.000
F20.3 Undifferentiated schizophrenia	0.004	0.996	0.000
F20.2 Catatonic schizophrenia	0.004	0.996	0.000
F20.1 Hebephrenic schizophrenia	0.004	0.996	0.000
G95.8 Other specified diseases of spinal cord	0.004	0.996	0.000
R50.0 Fever with chills	0.000	0.996	0.004
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.996	0.004
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.996	0.004
N40 Hyperplasia of prostate	0.000	0.996	0.004
O03.9 Complete or unspecified, without complication	0.000	0.996	0.004
F43.2 Adjustment disorders	0.004	0.996	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.996	0.004
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.996	0.004
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.004	0.996	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.004	0.996	0.000
H93.2 Other abnormal auditory perceptions	0.000	0.996	0.004
S06.21 Diffuse brain injury (with open intracranial wound)	0.004	0.996	0.000
G47.9 Sleep disorder, unspecified	0.000	0.996	0.004
Y60.9 During unspecified surgical and medical care	0.004	0.996	0.000
Y60.7 During administration of enema	0.004	0.996	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.004	0.996	0.000
Y60.5 During heart catheterisation	0.004	0.996	0.000
Y60.3 During injection or immunisation	0.004	0.996	0.000
Y60.2 During kidney dialysis or other perfusion	0.004	0.996	0.000
Y60.1 During infusion or transfusion	0.004	0.996	0.000
Y60.8 During other surgical and medical care	0.004	0.996	0.000
S06.7 Intracranial injury with prolonged coma	0.004	0.996	0.000
S06.1 Traumatic cerebral oedema	0.004	0.996	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.996	0.004
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.996	0.004
K85.8 Other acute pancreatitis	0.004	0.996	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.004	0.996	0.000
R52.1 Chronic intractable pain	0.004	0.996	0.000
S06.3 Focal brain injury	0.004	0.996	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.996	0.004
C32.9 Larynx, unspecified	0.000	0.996	0.004
S06.4 Epidural haemorrhage	0.004	0.996	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.004	0.996	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.996	0.003
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.003
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.004	0.996	0.000
K85.3 Drug-induced acute pancreatitis	0.004	0.996	0.000
K85.0 Idiopathic acute pancreatitis	0.004	0.996	0.000
K85.2 Alcohol-induced acute pancreatitis	0.003	0.996	0.000
S06.0 Concussion	0.003	0.996	0.000
E10.9 Without complications	0.000	0.996	0.004
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.996	0.003
C32.1 Supraglottis	0.000	0.997	0.003
C73 Malignant neoplasm of thyroid gland	0.003	0.997	0.000
J06.9 Acute upper respiratory infection, unspecified	0.000	0.997	0.003
S06.8 Other intracranial injuries	0.003	0.997	0.000
J32.8 Other chronic sinusitis	0.000	0.997	0.003
G95.0 Syringomyelia and syringobulbia	0.003	0.997	0.000
D24 Benign neoplasm of breast	0.000	0.997	0.003
E10 Insulin-dependent diabetes mellitus	0.000	0.997	0.003
G95 Other diseases of spinal cord	0.003	0.997	0.000
R50 Fever of unknown origin	0.000	0.997	0.003
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.003	0.997	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.003	0.997	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.003	0.997	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.003	0.997	0.000
L03.9 Cellulitis, unspecified	0.000	0.997	0.003
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.997	0.003
S06.31 Focal brain injury (with open intracranial wound)	0.003	0.997	0.000
K26.5 Chronic or unspecified with perforation	0.003	0.997	0.000
E10.2 With renal complications	0.000	0.997	0.003
Z73.9 Problem related to life-management difficulty, unspecified	0.003	0.997	0.000
E10.3 With ophthalmic complications	0.000	0.997	0.003
C32 Malignant neoplasm of larynx	0.000	0.997	0.003
E11.3 With ophthalmic complications	0.000	0.997	0.003
H43 Disorders of vitreous body	0.000	0.997	0.003
F40.2 Specific (isolated) phobias	0.003	0.997	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.997	0.003
S06.30 Focal brain injury (without open intracranial wound)	0.003	0.997	0.000
F43 Reaction to severe stress, and adjustment disorders	0.003	0.997	0.000
F40 Phobic anxiety disorders	0.003	0.997	0.000
F60 Specific personality disorders	0.003	0.997	0.000
R50.9 Fever, unspecified	0.000	0.997	0.003
R50.8 Other specified fever	0.000	0.997	0.003
S06.01 Concussion (with open intracranial wound)	0.003	0.997	0.000
E10.1 With ketoacidosis	0.000	0.997	0.003
O36.8 Maternal care for other specified foetal problems	0.003	0.997	0.000
F40.9 Phobic anxiety disorder, unspecified	0.003	0.997	0.000
G95.1 Vascular myelopathies	0.003	0.997	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
F60.0 Paranoid personality disorder	0.003	0.997	0.000
E10.4 With neurological complications	0.000	0.997	0.003
F69 Unspecified disorder of adult personality and behaviour	0.003	0.997	0.000
E10.8 With unspecified complications	0.000	0.997	0.003
F60.3 Emotionally unstable personality disorder	0.003	0.997	0.000
R50.1 Persistent fever	0.000	0.997	0.003
E10.0 With coma	0.000	0.997	0.003
G93.3 Postviral fatigue syndrome	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
H43.9 Disorder of vitreous body, unspecified	0.000	0.997	0.003
E10.7 With multiple complications	0.000	0.997	0.002
F43.0 Acute stress reaction	0.003	0.997	0.000
H18.4 Corneal degeneration	0.003	0.997	0.000
F60.9 Personality disorder, unspecified	0.003	0.997	0.000
F60.7 Dependent personality disorder	0.002	0.997	0.000
R50.2 Drug-induced fever	0.000	0.997	0.002
Z34.8 Supervision of other normal pregnancy	0.002	0.997	0.000
E10.6 With other specified complications	0.000	0.997	0.002
F48 Other neurotic disorders	0.002	0.997	0.000
H43.2 Crystalline deposits in vitreous body	0.000	0.997	0.002
C32.0 Glottis	0.000	0.997	0.002
C32.8 Overlapping lesion of larynx	0.000	0.998	0.002
C32.3 Laryngeal cartilage	0.000	0.998	0.002
C32.2 Subglottis	0.000	0.998	0.002
F48.9 Neurotic disorder, unspecified	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
K26 Duodenal ulcer	0.002	0.998	0.000
H16.0 Corneal ulcer	0.002	0.998	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.002	0.998	0.000
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
F60.8 Other specific personality disorders	0.002	0.998	0.000
H43.0 Vitreous prolapse	0.000	0.998	0.002
F60-F69 Disorders of adult personality and behaviour	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
F40.8 Other phobic anxiety disorders	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.000	0.998	0.002
S06.00 Concussion (without open intracranial wound)	0.002	0.998	0.000
F43.8 Other reactions to severe stress	0.002	0.998	0.000
F60.6 Anxious [avoidant] personality disorder	0.002	0.998	0.000
K26.7 Chronic without haemorrhage or perforation	0.002	0.998	0.000
M21.24 Flexion deformity (Hand)	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
F40.1 Social phobias	0.002	0.998	0.000
F60.4 Histrionic personality disorder	0.002	0.998	0.000
F60.2 Dissocial personality disorder	0.002	0.998	0.000
F60.1 Schizoid personality disorder	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.002	0.998	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.002	0.998	0.000
F40.0 Agoraphobia	0.002	0.998	0.000
C77.9 Lymph node, unspecified	0.002	0.998	0.000
F48.0 Neurasthenia	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
Z50.2 Alcohol rehabilitation	0.000	0.998	0.002
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
H91 Other hearing loss	0.000	0.998	0.002
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.002	0.998	0.000
F60.5 Anankastic personality disorder	0.002	0.998	0.000
F43.9 Reaction to severe stress, unspecified	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.998	0.002
H91.1 Presbycusis	0.000	0.998	0.002
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.001	0.998	0.002
F45 Somatoform disorders	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
M50-M54 Other dorsopathies	0.002	0.998	0.000
Z64 Problems related to certain psychosocial circumstances	0.002	0.998	0.000
G90-G99 Other disorders of the nervous system	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.002	0.998	0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.998	0.000
K26.2 Acute with both haemorrhage and perforation	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
M53 Other dorsopathies, not elsewhere classified	0.002	0.998	0.000
Z58 Problems related to physical environment	0.002	0.998	0.000
F48.8 Other specified neurotic disorders	0.002	0.998	0.000
F48.1 Depersonalisation-derealisation syndrome	0.002	0.998	0.000
G95.2 Cord compression, unspecified	0.002	0.998	0.000
H71 Cholesteatoma of middle ear	0.000	0.998	0.002
K26.1 Acute with perforation	0.002	0.998	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.002	0.998	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.002	0.998	0.000
Z64.0 Problems related to unwanted pregnancy	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
F68 Other disorders of adult personality and behaviour	0.002	0.998	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.002	0.998	0.000
F65 Disorders of sexual preference	0.002	0.998	0.000
F63 Habit and impulse disorders	0.002	0.998	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.002	0.998	0.000
F61 Mixed and other personality disorders	0.002	0.998	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.998	0.002
H43.3 Other vitreous opacities	0.000	0.998	0.002
F44 Dissociative [conversion] disorders	0.002	0.998	0.000
Z65 Problems related to other psychosocial circumstances	0.002	0.998	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.002	0.998	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.002	0.998	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.002	0.998	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.002	0.998	0.000
H16.4 Corneal neovascularisation	0.002	0.998	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.002	0.998	0.000
M20.2 Hallux rigidus	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
Z62 Other problems related to upbringing	0.002	0.998	0.000
Z55 Problems related to education and literacy	0.002	0.998	0.000
H91.2 Sudden idiopathic hearing loss	0.000	0.998	0.002
H91.0 Ototoxic hearing loss	0.000	0.998	0.002
Z58.1 Exposure to air pollution	0.002	0.998	0.000
Z61 Problems related to negative life events in childhood	0.002	0.998	0.000
F45.9 Somatoform disorder, unspecified	0.002	0.998	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
Z74.1 Need for assistance with personal care	0.000	0.998	0.002
H18 Other disorders of cornea	0.002	0.998	0.000
F45.8 Other somatoform disorders	0.002	0.998	0.000
M53.9 Dorsopathy, unspecified	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.002	0.998	0.000
G91 Hydrocephalus	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
K26.0 Acute with haemorrhage	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.002	0.998	0.000
F28 Other nonorganic psychotic disorders	0.002	0.998	0.000
F24 Induced delusional disorder	0.002	0.998	0.000
F21 Schizotypal disorder	0.002	0.998	0.000
F64 Gender identity disorders	0.002	0.998	0.000
F45.4 Persistent somatoform pain disorder	0.002	0.998	0.000
F45.2 Hypochondriacal disorder	0.002	0.998	0.000
F45.1 Undifferentiated somatoform disorder	0.002	0.998	0.000
M53.2 Spinal instabilities	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
F45.0 Somatisation disorder	0.002	0.998	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
Z64.4 Discord with counsellors	0.002	0.998	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.1 Problems related to multiparity	0.002	0.998	0.000
G92 Toxic encephalopathy	0.002	0.998	0.000
Z59 Problems related to housing and economic circumstances	0.002	0.998	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M53.8 Other specified dorsopathies	0.002	0.998	0.000
M53.1 Cervicobrachial syndrome	0.002	0.998	0.000
M53.0 Cervicocranial syndrome	0.002	0.998	0.000
Z58.9 Problem related to physical environment, unspecified	0.002	0.998	0.000
Z58.8 Other problems related to physical environment	0.002	0.998	0.000
Z58.6 Inadequate drinking-water supply	0.002	0.998	0.000
Z58.5 Exposure to other pollution	0.002	0.998	0.000
Z58.4 Exposure to radiation	0.002	0.998	0.000
Z58.3 Exposure to soil pollution	0.002	0.998	0.000
Z58.2 Exposure to water pollution	0.002	0.998	0.000
Z58.0 Exposure to noise	0.002	0.998	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.002	0.998	0.000
F45.3 Somatoform autonomic dysfunction	0.002	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.998	0.002
G90 Disorders of autonomic nervous system	0.002	0.998	0.000
G91.2 Normal-pressure hydrocephalus	0.002	0.998	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.002	0.998	0.000
E11.2 With renal complications	0.000	0.998	0.002
F62.9 Enduring personality change, unspecified	0.001	0.998	0.000
F62.8 Other enduring personality changes	0.001	0.998	0.000
F62.1 Enduring personality change after psychiatric illness	0.001	0.998	0.000
F62.0 Enduring personality change after catastrophic experience	0.001	0.998	0.000
F63.9 Habit and impulse disorder, unspecified	0.001	0.998	0.000
F63.8 Other habit and impulse disorders	0.001	0.998	0.000
F63.3 Trichotillomania	0.001	0.998	0.000
F63.2 Pathological stealing [kleptomania]	0.001	0.998	0.000
F63.1 Pathological fire-setting [pyromania]	0.001	0.998	0.000
F63.0 Pathological gambling	0.001	0.998	0.000
F65.9 Disorder of sexual preference, unspecified	0.001	0.998	0.000
F65.8 Other disorders of sexual preference	0.001	0.998	0.000
F65.6 Multiple disorders of sexual preference	0.001	0.998	0.000
F65.5 Sadomasochism	0.001	0.998	0.000
F65.4 Paedophilia	0.001	0.998	0.000
F65.3 Voyeurism	0.001	0.998	0.000
F65.2 Exhibitionism	0.001	0.998	0.000
F65.1 Fetishistic transvestism	0.001	0.998	0.000
F65.0 Fetishism	0.001	0.998	0.000
F66.9 Psychosexual development disorder, unspecified	0.001	0.998	0.000
F66.8 Other psychosexual development disorders	0.001	0.998	0.000
F66.2 Sexual relationship disorder	0.001	0.998	0.000
F66.1 Egodystonic sexual orientation	0.001	0.998	0.000
F66.0 Sexual maturation disorder	0.001	0.998	0.000
F68.8 Other specified disorders of adult personality and behaviour	0.001	0.998	0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.001	0.998	0.000
F68.0 Elaboration of physical symptoms for psychological reasons	0.001	0.998	0.000
G90.8 Other disorders of autonomic nervous system	0.002	0.998	0.000
G91.8 Other hydrocephalus	0.002	0.998	0.000
N48.4 Impotence of organic origin	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.002	0.998	0.000
F42 Obsessive-compulsive disorder	0.002	0.998	0.000
G96 Other disorders of central nervous system	0.002	0.998	0.000
F44.8 Other dissociative [conversion] disorders	0.001	0.998	0.000
F44.7 Mixed dissociative [conversion] disorders	0.001	0.998	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.001	0.998	0.000
F44.3 Trance and possession disorders	0.001	0.998	0.000
F44.2 Dissociative stupor	0.001	0.998	0.000
F44.1 Dissociative fugue	0.001	0.998	0.000
F44.0 Dissociative amnesia	0.001	0.998	0.000
G91.1 Obstructive hydrocephalus	0.002	0.998	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.001	0.998	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.001	0.998	0.000
Z65.4 Victim of crime and terrorism	0.001	0.998	0.000
Z65.3 Problems related to other legal circumstances	0.001	0.998	0.000
Z65.2 Problems related to release from prison	0.001	0.998	0.000
Z65.1 Imprisonment and other incarceration	0.001	0.998	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.001	0.998	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.998	0.002
Y64 Contaminated medical or biological substances	0.002	0.998	0.000
Y63 Failure in dosage during surgical and medical care	0.002	0.998	0.000
Y62 Failure of sterile precautions during surgical and medical care	0.002	0.998	0.000
Y61 Foreign object accidentally left in body during surgical and medical care	0.002	0.998	0.000
Y69 Unspecified misadventure during surgical and medical care	0.002	0.998	0.000
Y66 Nonadministration of surgical and medical care	0.002	0.998	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.002	0.998	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.002	0.998	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.002	0.998	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.002	0.998	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations