TreeWAS – Variant ID: rs6472155

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E21.0 Primary hyperparathyroidism	0.490	0.510	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.483	0.517	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.465	0.535	0.000
E21.3 Hyperparathyroidism, unspecified	0.430	0.570	0.000
E21.4 Other specified disorders of parathyroid gland	0.401	0.599	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.395	0.605	0.000
E21.2 Other hyperparathyroidism	0.363	0.637	0.000
E20-E35 Disorders of other endocrine glands	0.136	0.864	0.000
E26 Hyperaldosteronism	0.130	0.870	0.000
E26.0 Primary hyperaldosteronism	0.122	0.878	0.000
E34 Other endocrine disorders	0.117	0.883	0.000
E34.9 Endocrine disorder, unspecified	0.112	0.888	0.000
E26.9 Hyperaldosteronism, unspecified	0.111	0.889	0.000
E20 Hypoparathyroidism	0.103	0.896	0.000
E25 Adrenogenital disorders	0.103	0.897	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.097	0.902	0.000
E32 Diseases of thymus	0.097	0.902	0.000
E30 Disorders of puberty, not elsewhere classified	0.097	0.902	0.000
E26.8 Other hyperaldosteronism	0.093	0.906	0.000
E26.1 Secondary hyperaldosteronism	0.093	0.906	0.000
E28 Ovarian dysfunction	0.091	0.909	0.000
E31 Polyglandular dysfunction	0.090	0.910	0.000
E34.5 Androgen resistance syndrome	0.084	0.916	0.000
E34.4 Constitutional tall stature	0.084	0.916	0.000
E34.3 Short stature, not elsewhere classified	0.084	0.916	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.084	0.916	0.000
E34.1 Other hypersecretion of intestinal hormones	0.084	0.916	0.000
E22 Hyperfunction of pituitary gland	0.083	0.916	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.080	0.920	0.000
E29 Testicular dysfunction	0.080	0.920	0.000
E20.8 Other hypoparathyroidism	0.079	0.921	0.000
E34.0 Carcinoid syndrome	0.078	0.922	0.000
E20.9 Hypoparathyroidism, unspecified	0.076	0.924	0.000
E20.1 Pseudohypoparathyroidism	0.074	0.926	0.000
E20.0 Idiopathic hypoparathyroidism	0.074	0.926	0.000
E25.9 Adrenogenital disorder, unspecified	0.074	0.926	0.000
E25.8 Other adrenogenital disorders	0.074	0.926	0.000
E22.1 Hyperprolactinaemia	0.071	0.929	0.000
E30.9 Disorder of puberty, unspecified	0.070	0.930	0.000
E30.8 Other disorders of puberty	0.070	0.930	0.000
E30.1 Precocious puberty	0.070	0.930	0.000
E30.0 Delayed puberty	0.070	0.930	0.000
E32.9 Disease of thymus, unspecified	0.070	0.930	0.000
E32.8 Other diseases of thymus	0.070	0.930	0.000
E32.1 Abscess of thymus	0.070	0.930	0.000
E32.0 Persistent hyperplasia of thymus	0.070	0.930	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.070	0.930	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.070	0.930	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.070	0.930	0.000
E28.2 Polycystic ovarian syndrome	0.067	0.933	0.000
E28.9 Ovarian dysfunction, unspecified	0.066	0.934	0.000
E28.8 Other ovarian dysfunction	0.066	0.934	0.000
E28.1 Androgen excess	0.066	0.934	0.000
E28.0 Oestrogen excess	0.066	0.934	0.000
E31.9 Polyglandular dysfunction, unspecified	0.065	0.935	0.000
E31.8 Other polyglandular dysfunction	0.065	0.935	0.000
E31.1 Polyglandular hyperfunction	0.065	0.935	0.000
E24 Cushing's syndrome	0.065	0.935	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.060	0.940	0.000
E22.8 Other hyperfunction of pituitary gland	0.060	0.940	0.000
E29.9 Testicular dysfunction, unspecified	0.057	0.942	0.000
E29.8 Other testicular dysfunction	0.057	0.942	0.000
E29.0 Testicular hyperfunction	0.057	0.942	0.000
E28.3 Primary ovarian failure	0.057	0.942	0.000
E31.0 Autoimmune polyglandular failure	0.057	0.942	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.054	0.946	0.000
E34.8 Other specified endocrine disorders	0.052	0.947	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.046	0.953	0.000
E24.3 Ectopic ACTH syndrome	0.046	0.953	0.000
E24.1 Nelson's syndrome	0.046	0.953	0.000
E23 Hypofunction and other disorders of pituitary gland	0.045	0.955	0.000
E24.2 Drug-induced Cushing's syndrome	0.044	0.956	0.000
E24.0 Pituitary-dependent Cushing's disease	0.042	0.958	0.000
E24.8 Other Cushing's syndrome	0.041	0.958	0.000
E29.1 Testicular hypofunction	0.040	0.960	0.000
E27 Other disorders of adrenal gland	0.038	0.962	0.000
E24.9 Cushing's syndrome, unspecified	0.037	0.963	0.000
E23.7 Disorder of pituitary gland, unspecified	0.033	0.967	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.033	0.967	0.000
E23.1 Drug-induced hypopituitarism	0.033	0.967	0.000
E27.8 Other specified disorders of adrenal gland	0.030	0.970	0.000
E27.9 Disorder of adrenal gland, unspecified	0.029	0.971	0.000
E23.2 Diabetes insipidus	0.029	0.971	0.000
E22.0 Acromegaly and pituitary gigantism	0.029	0.971	0.000
E27.5 Adrenomedullary hyperfunction	0.028	0.972	0.000
E27.0 Other adrenocortical overactivity	0.028	0.972	0.000
E23.6 Other disorders of pituitary gland	0.025	0.975	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.025	0.975	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.023	0.977	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.020	0.980	0.000
E27.2 Addisonian crisis	0.013	0.986	0.001
C78.2 Secondary malignant neoplasm of pleura	0.013	0.987	0.000
E27.1 Primary adrenocortical insufficiency	0.013	0.987	0.000
E23.0 Hypopituitarism	0.012	0.988	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.008	0.992	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.992	0.008
T81.3 Disruption of operation wound, not elsewhere classified	0.008	0.992	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.995	0.005
T43.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.995	0.004
M95.0 Acquired deformity of nose	0.004	0.996	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.996	0.004
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.996	0.004
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.996	0.004
N13 Obstructive and reflux uropathy	0.000	0.997	0.003
N13.4 Hydroureter	0.000	0.997	0.003
M18 Arthrosis of first carpometacarpal joint	0.003	0.997	0.000
H52.2 Astigmatism	0.000	0.997	0.003
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
N13.3 Other and unspecified hydronephrosis	0.000	0.997	0.003
C43.6 Malignant melanoma of upper limb, including shoulder	0.003	0.997	0.000
T86.1 Kidney transplant failure and rejection	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.003
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.003	0.997	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.003	0.997	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.003	0.997	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.003	0.997	0.000
C34.2 Middle lobe, bronchus or lung	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.997	0.002
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.997	0.003
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.997	0.003
T38.1 Thyroid hormones and substitutes	0.000	0.997	0.002
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.003	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.997	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.997	0.000
Z90.8 Acquired absence of other organs	0.003	0.997	0.000
I87.8 Other specified disorders of veins	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.998	0.002
L53.8 Other specified erythematous conditions	0.002	0.998	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.002	0.998	0.000
C83.0 Small cell (diffuse)	0.002	0.998	0.000
L53.9 Erythematous condition, unspecified	0.002	0.998	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.998	0.002
C79.2 Secondary malignant neoplasm of skin	0.000	0.998	0.002
E87.5 Hyperkalaemia	0.002	0.998	0.000
K60.1 Chronic anal fissure	0.000	0.998	0.002
N13.6 Pyonephrosis	0.000	0.998	0.002
M95.4 Acquired deformity of chest and rib	0.002	0.998	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.998	0.002
M62.9 Disorder of muscle, unspecified	0.002	0.998	0.000
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
M62.96 Disorder of muscle, unspecified (Lower leg)	0.002	0.998	0.000
M95.1 Cauliflower ear	0.002	0.998	0.000
M62.99 Disorder of muscle, unspecified (Site unspecified)	0.002	0.998	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.002	0.998	0.000
M95.5 Acquired deformity of pelvis	0.002	0.998	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.002	0.998	0.000
L53 Other erythematous conditions	0.002	0.998	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.998	0.002
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.000	0.998	0.002
C83 Diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.998	0.002
M95.2 Other acquired deformity of head	0.002	0.998	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.998	0.002
M62 Other disorders of muscle	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M79.00 Rheumatism, unspecified (Multiple sites)	0.000	0.998	0.002
M95.3 Acquired deformity of neck	0.002	0.998	0.000
C83.2 Mixed small and large cell (diffuse)	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.000	0.998	0.002
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
M62.6 Muscle strain	0.002	0.998	0.000
M62.0 Diastasis of muscle	0.002	0.998	0.000
M62.08 Diastasis of muscle (Other)	0.002	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.998	0.002
L53.0 Toxic erythema	0.002	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
O43.1 Malformation of placenta	0.000	0.998	0.002
T92.1 Sequelae of fracture of arm	0.000	0.998	0.002
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
M62.98 Disorder of muscle, unspecified (Other)	0.002	0.998	0.000
M62.97 Disorder of muscle, unspecified (Ankle and foot)	0.002	0.998	0.000
M62.95 Disorder of muscle, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M62.94 Disorder of muscle, unspecified (Hand)	0.002	0.998	0.000
M62.93 Disorder of muscle, unspecified (Forearm)	0.002	0.998	0.000
M62.92 Disorder of muscle, unspecified (Upper arm)	0.002	0.998	0.000
M62.91 Disorder of muscle, unspecified (Shoulder region)	0.002	0.998	0.000
M62.90 Disorder of muscle, unspecified (Multiple sites)	0.002	0.998	0.000
C83.5 Lymphoblastic (diffuse)	0.002	0.998	0.000
R07.0 Pain in throat	0.000	0.998	0.002
K83.0 Cholangitis	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.002	0.998	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.002	0.998	0.000
L53.3 Other chronic figurate erythema	0.002	0.998	0.000
L53.2 Erythema marginatum	0.002	0.998	0.000
L53.1 Erythema annulare centrifugum	0.002	0.998	0.000
M62.66 Muscle strain (Lower leg)	0.002	0.998	0.000
H53.0 Amblyopia ex anopsia	0.000	0.998	0.002
K82.3 Fistula of gallbladder	0.000	0.998	0.002
Z63.8 Other specified problems related to primary support group	0.000	0.998	0.002
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
C83.7 Burkitt's tumour	0.002	0.998	0.000
C83.6 Undifferentiated (diffuse)	0.002	0.998	0.000
C83.4 Immunoblastic (diffuse)	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.998	0.002
Q12.0 Congenital cataract	0.000	0.998	0.002
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
M62.4 Contracture of muscle	0.002	0.998	0.000
M62.3 Immobility syndrome (paraplegic)	0.002	0.998	0.000
M62.2 Ischaemic infarction of muscle	0.002	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.002	0.998	0.000
M21.8 Other specified acquired deformities of limbs	0.002	0.998	0.000
I24 Other acute ischaemic heart diseases	0.000	0.998	0.002
J04.0 Acute laryngitis	0.002	0.998	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.002	0.998	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.001	0.998	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.001	0.998	0.000
M62.06 Diastasis of muscle (Lower leg)	0.001	0.998	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.04 Diastasis of muscle (Hand)	0.001	0.998	0.000
M62.03 Diastasis of muscle (Forearm)	0.001	0.998	0.000
M62.02 Diastasis of muscle (Upper arm)	0.001	0.998	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.001	0.998	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.001	0.998	0.000
M62.69 Muscle strain (Site unspecified)	0.001	0.998	0.000
M62.68 Muscle strain (Other)	0.001	0.998	0.000
M62.67 Muscle strain (Ankle and foot)	0.001	0.998	0.000
M62.64 Muscle strain (Hand)	0.001	0.998	0.000
M62.63 Muscle strain (Forearm)	0.001	0.998	0.000
M62.62 Muscle strain (Upper arm)	0.001	0.998	0.000
M62.61 Muscle strain (Shoulder region)	0.001	0.998	0.000
M62.60 Muscle strain (Multiple sites)	0.001	0.998	0.000
D23.7 Skin of lower limb, including hip	0.000	0.998	0.002
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.002	0.998	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.002	0.998	0.000
I70.0 Atherosclerosis of aorta	0.002	0.998	0.000
L81.9 Disorder of pigmentation, unspecified	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
H02.0 Entropion and trichiasis of eyelid	0.000	0.998	0.002
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.998	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.001	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.001	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.998	0.000
C34.1 Upper lobe, bronchus or lung	0.002	0.998	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
T98 Sequelae of other and unspecified effects of external causes	0.000	0.998	0.002
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.001	0.998	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.998	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.001	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.001	0.998	0.000
D68.5 Primary Thrombophilia	0.000	0.998	0.002
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.998	0.001
O12.1 Gestational proteinuria	0.000	0.998	0.001
T90.9 Sequelae of unspecified injury of head	0.000	0.998	0.002
V23.4 Driver injured in traffic accident	0.000	0.998	0.002
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.001	0.998	0.000
M62.28 Ischaemic infarction of muscle (Other)	0.001	0.998	0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.001	0.998	0.000
M62.26 Ischaemic infarction of muscle (Lower leg)	0.001	0.998	0.000
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.24 Ischaemic infarction of muscle (Hand)	0.001	0.998	0.000
M62.23 Ischaemic infarction of muscle (Forearm)	0.001	0.998	0.000
M62.22 Ischaemic infarction of muscle (Upper arm)	0.001	0.998	0.000
M62.21 Ischaemic infarction of muscle (Shoulder region)	0.001	0.998	0.000
M62.20 Ischaemic infarction of muscle (Multiple sites)	0.001	0.998	0.000
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.001	0.998	0.000
M62.38 Immobility syndrome (paraplegic) (Other)	0.001	0.998	0.000
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.001	0.998	0.000
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.001	0.998	0.000
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.001	0.998	0.000
M62.34 Immobility syndrome (paraplegic) (Hand)	0.001	0.998	0.000
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.001	0.998	0.000
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.001	0.998	0.000
M62.31 Immobility syndrome (paraplegic) (Shoulder region)	0.001	0.998	0.000
M62.30 Immobility syndrome (paraplegic) (Multiple sites)	0.001	0.998	0.000
M62.49 Contracture of muscle (Site unspecified)	0.001	0.998	0.000
M62.48 Contracture of muscle (Other)	0.001	0.998	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.001	0.998	0.000
M62.46 Contracture of muscle (Lower leg)	0.001	0.998	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.44 Contracture of muscle (Hand)	0.001	0.998	0.000
M62.43 Contracture of muscle (Forearm)	0.001	0.998	0.000
M62.42 Contracture of muscle (Upper arm)	0.001	0.998	0.000
M62.41 Contracture of muscle (Shoulder region)	0.001	0.998	0.000
M62.40 Contracture of muscle (Multiple sites)	0.001	0.998	0.000
B01.9 Varicella without complications	0.000	0.998	0.001
C41.4 Pelvic bones, sacrum and coccyx	0.001	0.998	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.001	0.999	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.001	0.999	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.001	0.999	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.001	0.999	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.001	0.999	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.001	0.999	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
I78.1 Naevus, nonneoplastic	0.000	0.999	0.001
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.999	0.001
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.999	0.001
G44 Other headache syndromes	0.000	0.999	0.001
I70.01 Atherosclerosis of aorta (with gangrene)	0.001	0.999	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.001	0.999	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.001	0.999	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.001	0.999	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.001	0.999	0.000
G44.3 Chronic posttraumatic headache	0.000	0.999	0.001
N81.5 Vaginal enterocele	0.001	0.999	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.001	0.999	0.000
D37.7 Other digestive organs	0.000	0.999	0.001
E06.3 Autoimmune thyroiditis	0.001	0.999	0.000
I24.1 Dressler's syndrome	0.000	0.999	0.001
M21.83 Other specified acquired deformities of limbs (Forearm)	0.001	0.999	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.001	0.999	0.000
F02.3 Dementia in Parkinson's disease	0.001	0.999	0.000
G44.2 Tension-type headache	0.000	0.999	0.001
C32.2 Subglottis	0.001	0.999	0.000
O87.2 Haemorrhoids in the puerperium	0.001	0.999	0.000
T98.2 Sequelae of certain early complications of trauma	0.000	0.999	0.001
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.000	0.999	0.001
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.001	0.999	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.001	0.999	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.001	0.999	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.001	0.999	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.001	0.999	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.001	0.999	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.001	0.999	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.001	0.999	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.001	0.999	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.999	0.001
I24.8 Other forms of acute ischaemic heart disease	0.000	0.999	0.001
I83.0 Varicose veins of lower extremities with ulcer	0.001	0.999	0.000
M14.6 Neuropathic arthropathy	0.001	0.999	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.001	0.999	0.000
K63.9 Disease of intestine, unspecified	0.001	0.999	0.000
T93.0 Sequelae of open wound of lower limb	0.000	0.999	0.001
M79.08 Rheumatism, unspecified (Other)	0.000	0.999	0.001
M60.05 Infective myositis (Pelvic region and thigh)	0.000	0.999	0.001
C41.1 Mandible	0.001	0.999	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.999	0.001
M25.96 Joint disorder, unspecified (Lower leg)	0.001	0.999	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.999	0.000
I63.8 Other cerebral infarction	0.001	0.999	0.000
Q17.5 Prominent ear	0.000	0.999	0.001
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.000	0.999	0.001
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.000	0.999	0.001
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.001	0.999	0.000
G31.8 Other specified degenerative diseases of nervous system	0.001	0.999	0.000
G44.8 Other specified headache syndromes	0.000	0.999	0.001
M88.9 Paget's disease of bone, unspecified	0.000	0.999	0.001
O90.1 Disruption of perineal obstetric wound	0.001	0.999	0.000
R90.0 Intracranial space-occupying lesion	0.000	0.999	0.001
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
F50.9 Eating disorder, unspecified	0.000	0.999	0.001
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.999	0.001
M46.46 Discitis, unspecified (Lumbar region)	0.001	0.999	0.000
C32.3 Laryngeal cartilage	0.001	0.999	0.000
C41.3 Ribs, sternum and clavicle	0.001	0.999	0.000
T90.4 Sequelae of injury of eye and orbit	0.000	0.999	0.001
N11 Chronic tubulo-interstitial nephritis	0.000	0.999	0.001
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
G44.1 Vascular headache, not elsewhere classified	0.000	0.999	0.001
L51.9 Erythema multiforme, unspecified	0.000	0.999	0.001
L93.0 Discoid lupus erythematosus	0.000	0.999	0.001
N99.5 Malfunction of external stoma of urinary tract	0.000	0.999	0.001
T90.8 Sequelae of other specified injuries of head	0.000	0.999	0.001
Z48.9 Surgical follow-up care, unspecified	0.001	0.999	0.000
I08 Multiple valve diseases	0.001	0.999	0.000
L52 Erythema nodosum	0.001	0.999	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.001	0.999	0.001
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.001	0.999	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.999	0.001
M79.0 Rheumatism, unspecified	0.000	0.999	0.001
I38 Endocarditis, valve unspecified	0.000	0.999	0.001
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)	0.001	0.999	0.000
J94.8 Other specified pleural conditions	0.001	0.999	0.000
N50.0 Atrophy of testis	0.000	0.999	0.001
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.999	0.001
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.999	0.001
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.999	0.001
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.999	0.001
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.999	0.001
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.999	0.001
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.999	0.001
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.999	0.001
C08.9 Major salivary gland, unspecified	0.000	0.999	0.001
I84.7 Unspecified thrombosed haemorrhoids	0.001	0.999	0.000
K10.0 Developmental disorders of jaws	0.001	0.999	0.000
M96.5 Postradiation scoliosis	0.001	0.999	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.001	0.999	0.000
T90 Sequelae of injuries of head	0.000	0.999	0.001
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.001	0.999	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.001	0.999	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.999	0.001
T90.0 Sequelae of superficial injury of head	0.000	0.999	0.001
M21.22 Flexion deformity (Upper arm)	0.001	0.999	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.001	0.999	0.000
M90.80 Osteopathy in other diseases classified elsewhere (Multiple sites)	0.001	0.999	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.001	0.999	0.000
C34 Malignant neoplasm of bronchus and lung	0.001	0.999	0.000
C32 Malignant neoplasm of larynx	0.001	0.999	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.001	0.999	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.001	0.999	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M79.04 Rheumatism, unspecified (Hand)	0.000	0.999	0.001
M79.03 Rheumatism, unspecified (Forearm)	0.000	0.999	0.001
M79.02 Rheumatism, unspecified (Upper arm)	0.000	0.999	0.001
I33.0 Acute and subacute infective endocarditis	0.001	0.999	0.000
K10.3 Alveolitis of jaws	0.001	0.999	0.000
L50.9 Urticaria, unspecified	0.001	0.999	0.000
O86.0 Infection of obstetric surgical wound	0.000	0.999	0.001
S10.9 Superficial injury of neck, part unspecified	0.001	0.999	0.000
T46.1 Calcium-channel blockers	0.000	0.999	0.001
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.001	0.999	0.000
Y44.2 Anticoagulants	0.001	0.999	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.000	0.999	0.001
M79.18 Myalgia (Other)	0.000	0.999	0.001
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.001	0.999	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
K82.1 Hydrops of gallbladder	0.000	0.999	0.001
M34.1 CR(E)ST syndrome	0.000	0.999	0.001
M90.8 Osteopathy in other diseases classified elsewhere	0.001	0.999	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.999	0.001
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.999	0.001
T82.3 Mechanical complication of other vascular grafts	0.001	0.999	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.001	0.999	0.000
Z60.2 Living alone	0.000	0.999	0.001
T80 Complications following infusion, transfusion and therapeutic injection	0.001	0.999	0.000
M60.08 Infective myositis (Other)	0.000	0.999	0.001
M79.01 Rheumatism, unspecified (Shoulder region)	0.000	0.999	0.001
S02.80 Fractures of other skull and facial bones (closed)	0.001	0.999	0.000
C32.0 Glottis	0.001	0.999	0.000
C41.8 Overlapping lesion of bone and articular cartilage	0.001	0.999	0.000
M60.0 Infective myositis	0.000	0.999	0.001
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.001	0.999	0.000
M96.4 Postsurgical lordosis	0.001	0.999	0.000
M96.3 Postlaminectomy kyphosis	0.001	0.999	0.000
M96.2 Postradiation kyphosis	0.001	0.999	0.000
N11.1 Chronic obstructive pyelonephritis	0.000	0.999	0.001
N99.2 Postprocedural adhesions of vagina	0.000	0.999	0.001
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
T90.3 Sequelae of injury of cranial nerves	0.000	0.999	0.001
U81.0 Vancomycin resistant agent	0.001	0.999	0.000
Q12 Congenital lens malformations	0.000	0.999	0.001
M90.19 Periostitis in other infectious diseases classified elsewhere (Site unspecified)	0.001	0.999	0.000
M90.18 Periostitis in other infectious diseases classified elsewhere (Other)	0.001	0.999	0.000
M90.17 Periostitis in other infectious diseases classified elsewhere (Ankle and foot)	0.001	0.999	0.000
M90.16 Periostitis in other infectious diseases classified elsewhere (Lower leg)	0.001	0.999	0.000
M90.15 Periostitis in other infectious diseases classified elsewhere (Pelvic region and thigh)	0.001	0.999	0.000
M90.14 Periostitis in other infectious diseases classified elsewhere (Hand)	0.001	0.999	0.000
M90.13 Periostitis in other infectious diseases classified elsewhere (Forearm)	0.001	0.999	0.000
M90.12 Periostitis in other infectious diseases classified elsewhere (Upper arm)	0.001	0.999	0.000
M90.11 Periostitis in other infectious diseases classified elsewhere (Shoulder region)	0.001	0.999	0.000
M90.84 Osteopathy in other diseases classified elsewhere (Hand)	0.001	0.999	0.000
C21.0 Anus, unspecified	0.001	0.999	0.000
C32.8 Overlapping lesion of larynx	0.001	0.999	0.000
C41.2 Vertebral column	0.001	0.999	0.000
F50.2 Bulimia nervosa	0.000	0.999	0.001
K10.8 Other specified diseases of jaws	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations