TreeWAS – Variant ID: rs6473383

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z85.3 Personal history of malignant neoplasm of breast	0.000	0.902	0.098
H04.1 Other disorders of lachrymal gland	0.011	0.989	0.000
Y45.2 Propionic acid derivatives	0.009	0.991	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.008	0.992	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
Y45.8 Other analgesics and antipyretics	0.008	0.992	0.000
Y45.5 4-Aminophenol derivatives	0.007	0.993	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.006	0.994	0.000
Y45.4 Antirheumatics	0.006	0.994	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.994	0.006
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.994	0.006
Y44.2 Anticoagulants	0.006	0.994	0.000
Y45.0 Opioids and related analgesics	0.006	0.994	0.000
Z80.3 Family history of malignant neoplasm of breast	0.000	0.995	0.005
H02.9 Disorder of eyelid, unspecified	0.000	0.995	0.005
H61.2 Impacted cerumen	0.000	0.995	0.005
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.995	0.005
D69.6 Thrombocytopenia, unspecified	0.000	0.995	0.005
G63.2 Diabetic polyneuropathy	0.005	0.995	0.000
Y45.1 Salicylates	0.004	0.995	0.000
Y44 Agents primarily affecting blood constituents	0.004	0.996	0.000
M54.22 Cervicalgia (Cervical region)	0.000	0.996	0.004
C25.9 Pancreas, unspecified	0.000	0.996	0.004
C25.0 Head of pancreas	0.000	0.996	0.004
C25 Malignant neoplasm of pancreas	0.000	0.996	0.004
Z51.3 Blood transfusion without reported diagnosis	0.000	0.996	0.004
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
C25.2 Tail of pancreas	0.000	0.996	0.004
S22.0 Fracture of thoracic vertebra	0.000	0.996	0.004
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.000	0.996	0.004
Y44.9 Other and unspecified agents affecting blood constituents	0.003	0.997	0.000
Y44.7 Plasma substitutes	0.003	0.997	0.000
Y44.6 Natural blood and blood products	0.003	0.997	0.000
Y44.5 Thrombolytic drugs	0.003	0.997	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.003	0.997	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.003	0.997	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.003	0.997	0.000
N76.4 Abscess of vulva	0.003	0.997	0.000
C15.9 Oesophagus, unspecified	0.003	0.997	0.000
C25.1 Body of pancreas	0.000	0.997	0.003
S42.2 Fracture of upper end of humerus	0.000	0.997	0.003
O16 Unspecified maternal hypertension	0.003	0.997	0.000
N76.3 Subacute and chronic vulvitis	0.003	0.997	0.000
S52.50 Fracture of lower end of radius (closed)	0.003	0.997	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.997	0.003
C25.7 Other parts of pancreas	0.000	0.997	0.003
C25.4 Endocrine pancreas	0.000	0.997	0.003
C25.3 Pancreatic duct	0.000	0.997	0.003
C15.5 Lower third of oesophagus	0.003	0.997	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.003	0.997	0.000
N76.8 Other specified inflammation of vagina and vulva	0.003	0.997	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.003	0.997	0.000
M50.3 Other cervical disk degeneration	0.000	0.997	0.003
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.000	0.997	0.003
N76 Other inflammation of vagina and vulva	0.003	0.997	0.000
O14.9 Preeclampsia, unspecified	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
O14.1 Severe preeclampsia	0.003	0.997	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.997	0.003
C85.1 B-cell lymphoma, unspecified	0.003	0.997	0.000
O14.0 Moderate preeclampsia	0.003	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
C15 Malignant neoplasm of oesophagus	0.003	0.997	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.997	0.003
S42.21 Fracture of upper end of humerus (open)	0.000	0.997	0.003
X49.9 Unspecified place	0.000	0.997	0.003
C16.0 Cardia	0.003	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
S52.51 Fracture of lower end of radius (open)	0.003	0.997	0.000
Z99.3 Dependence on wheelchair	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.997	0.000
N76.2 Acute vulvitis	0.002	0.997	0.000
O14.2 HELLP syndrome	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
S52.5 Fracture of lower end of radius	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.000	0.998	0.002
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.000	0.998	0.002
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.000	0.998	0.002
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.000	0.998	0.002
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.000	0.998	0.002
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.000	0.998	0.002
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.000	0.998	0.002
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.000	0.998	0.002
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.000	0.998	0.002
C15.4 Middle third of oesophagus	0.002	0.998	0.000
N76.5 Ulceration of vagina	0.002	0.998	0.000
N76.1 Subacute and chronic vaginitis	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
C15.8 Overlapping lesion of oesophagus	0.002	0.998	0.000
C15.2 Abdominal part of oesophagus	0.002	0.998	0.000
C15.1 Thoracic part of oesophagus	0.002	0.998	0.000
C15.0 Cervical part of oesophagus	0.002	0.998	0.000
E14.3 With ophthalmic complications	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
C15.3 Upper third of oesophagus	0.002	0.998	0.000
O63.9 Long labour, unspecified	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.998	0.002
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
O15 Eclampsia	0.002	0.998	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.002	0.998	0.000
N02.8 Other	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
D69.0 Allergic purpura	0.000	0.998	0.002
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.002	0.998	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
N76.0 Acute vaginitis	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
S22.20 Fracture of sternum (closed)	0.000	0.998	0.002
D69 Purpura and other haemorrhagic conditions	0.000	0.998	0.002
C85.7 Other specified types of non-Hodgkin's lymphoma	0.002	0.998	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.998	0.002
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
D23.3 Skin of other and unspecified parts of face	0.000	0.998	0.002
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
S22.2 Fracture of sternum	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Z04.8 Examination and observation for other specified reasons	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
L05.0 Pilonidal cyst with abscess	0.000	0.998	0.002
N76.6 Ulceration of vulva	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
S22.50 Flail chest (closed)	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.000	0.998	0.002
G63.8 Polyneuropathy in other diseases classified elsewhere	0.002	0.998	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.002	0.998	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.002	0.998	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.002	0.998	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.002	0.998	0.000
G63.1 Polyneuropathy in neoplastic disease	0.002	0.998	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
S22.5 Flail chest	0.000	0.998	0.002
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.002	0.998	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.998	0.002
H61 Other disorders of external ear	0.000	0.998	0.002
O15.9 Eclampsia, unspecified as to time period	0.002	0.998	0.000
O15.2 Eclampsia in the puerperium	0.002	0.998	0.000
O15.1 Eclampsia in labour	0.002	0.998	0.000
O15.0 Eclampsia in pregnancy	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.000	0.998	0.002
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.998	0.002
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.002	0.998	0.000
C85.0 Lymphosarcoma	0.002	0.998	0.000
D69.4 Other primary thrombocytopenia	0.000	0.998	0.002
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
N05.9 Unspecified	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.002
Y56.9 Topical agent, unspecified	0.001	0.998	0.000
Y56.8 Other topical agents	0.001	0.998	0.000
Y56.7 Dental drugs, topically applied	0.001	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.998	0.000
Y56.2 Local astringents and local detergents	0.001	0.998	0.000
Y56.1 Antipruritics	0.001	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.002	0.998	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.998	0.002
D69.1 Qualitative platelet defects	0.000	0.998	0.002
I51.9 Heart disease, unspecified	0.000	0.998	0.002
X62.9 Unspecified place	0.000	0.998	0.002
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.002
T83.0 Mechanical complication of urinary (indwelling) catheter	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.001	0.998	0.000
T63.4 Venom of other arthropods	0.000	0.998	0.002
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
S22.21 Fracture of sternum (open)	0.000	0.998	0.001
C83.3 Large cell (diffuse)	0.002	0.998	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.002	0.998	0.000
D35.1 Parathyroid gland	0.000	0.998	0.002
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
Y40.0 Penicillins	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
Y52.7 Peripheral vasodilators	0.001	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
H35.0 Background retinopathy and retinal vascular changes	0.002	0.998	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
S22.51 Flail chest (open)	0.000	0.998	0.001
O12.2 Gestational oedema with proteinuria	0.001	0.998	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.998	0.001
S22.8 Fracture of other parts of bony thorax	0.000	0.998	0.001
D69.2 Other nonthrombocytopenic purpura	0.000	0.998	0.001
H61.8 Other specified disorders of external ear	0.000	0.998	0.001
S22.1 Multiple fractures of thoracic spine	0.000	0.998	0.001
S32.40 Fracture of acetabulum (closed)	0.000	0.998	0.002
Y46.4 Iminostilbenes	0.001	0.998	0.000
M53 Other dorsopathies, not elsewhere classified	0.000	0.998	0.001
N87.0 Mild cervical dysplasia	0.002	0.998	0.000
J80 Adult respiratory distress syndrome	0.001	0.998	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.000	0.998	0.001
B08.1 Molluscum contagiosum	0.001	0.999	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.999	0.001
O12.1 Gestational proteinuria	0.001	0.999	0.000
M50 Cervical disk disorders	0.000	0.999	0.001
D69.5 Secondary thrombocytopenia	0.000	0.999	0.001
M54.2 Cervicalgia	0.000	0.999	0.001
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.001	0.999	0.000
Y57.5 X-ray contrast media	0.001	0.999	0.000
S82.3 Fracture of lower end of tibia	0.001	0.999	0.000
Y48.3 Local anaesthetics	0.001	0.999	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
Y57.9 Drug or medicament, unspecified	0.001	0.999	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.999	0.001
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.999	0.001
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.999	0.001
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.999	0.001
B18.2 Chronic viral hepatitis C	0.000	0.999	0.001
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.999	0.001
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
Q65 Congenital deformities of hip	0.001	0.999	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.001	0.999	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.001	0.999	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.999	0.001
H61.1 Non-infective disorders of pinna	0.000	0.999	0.001
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O12.0 Gestational oedema	0.001	0.999	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.001	0.999	0.000
T87.4 Infection of amputation stump	0.001	0.999	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.999	0.001
K74.3 Primary biliary cirrhosis	0.000	0.999	0.001
M53.9 Dorsopathy, unspecified	0.000	0.999	0.001
M53.1 Cervicobrachial syndrome	0.000	0.999	0.001
M53.0 Cervicocranial syndrome	0.000	0.999	0.001
O92.1 Cracked nipple associated with childbirth	0.001	0.999	0.000
X49.4 Street and highway	0.000	0.999	0.001
X49.0 Home	0.000	0.999	0.001
X49.8 Other specified place	0.000	0.999	0.001
X49.7 Farm	0.000	0.999	0.001
X49.6 Industrial and construction area	0.000	0.999	0.001
X49.5 Trade and service area	0.000	0.999	0.001
X49.3 Sports and athletics area	0.000	0.999	0.001
X49.2 School, other institution and public administrative area	0.000	0.999	0.001
X49.1 Residential institution	0.000	0.999	0.001
Y52.1 Calcium-channel blockers	0.001	0.999	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.001	0.999	0.000
M50.8 Other cervical disk disorders	0.000	0.999	0.001
M54.28 Cervicalgia-Sacral/sacrococ	0.000	0.999	0.001
M54.27 Cervicalgia-Lumbosacral	0.000	0.999	0.001
M54.26 Cervicalgia-Lumbar	0.000	0.999	0.001
M54.25 Cervicalgia-Thoracolumbar	0.000	0.999	0.001
M54.24 Cervicalgia-Thoracic	0.000	0.999	0.001
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.000	0.999	0.001
M54.20 Cervicalgia-Mult site	0.000	0.999	0.001
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.999	0.001
M54.23 Cervicalgia (Cervicothoracic region)	0.000	0.999	0.001
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.999	0.001
M53.8 Other specified dorsopathies	0.000	0.999	0.001
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
Z99.8 Dependence on other enabling machines and devices	0.001	0.999	0.000
M06.34 Rheumatoid nodule (Hand)	0.001	0.999	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M53.2 Spinal instabilities	0.000	0.999	0.001
Q65.9 Congenital deformity of hip, unspecified	0.001	0.999	0.000
Q65.6 Unstable hip	0.001	0.999	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.001	0.999	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.001	0.999	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.001	0.999	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.999	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.001	0.999	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.001	0.999	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.001	0.999	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.001	0.999	0.000
T83.2 Mechanical complication of graft of urinary organ	0.001	0.999	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
M53.09 Cervicocranial syndrome-Site unspe	0.000	0.999	0.001
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.000	0.999	0.001
M53.07 Cervicocranial syndrome-Lumbosacral	0.000	0.999	0.001
M53.06 Cervicocranial syndrome-Lumbar	0.000	0.999	0.001
M53.05 Cervicocranial syndrome-Thoracolumbar	0.000	0.999	0.001
M53.04 Cervicocranial syndrome-Thoracic	0.000	0.999	0.001
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.000	0.999	0.001
M53.02 Cervicocranial syndrome (Cervical region)	0.000	0.999	0.001
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.000	0.999	0.001
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.000	0.999	0.001
M53.19 Cervicobrachial syndrome-Site unspe	0.000	0.999	0.001
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.000	0.999	0.001
M53.17 Cervicobrachial syndrome-Lumbosacral	0.000	0.999	0.001
M53.16 Cervicobrachial syndrome-Lumbar	0.000	0.999	0.001
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.000	0.999	0.001
M53.14 Cervicobrachial syndrome-Thoracic	0.000	0.999	0.001
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.000	0.999	0.001
M53.12 Cervicobrachial syndrome (Cervical region)	0.000	0.999	0.001
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.000	0.999	0.001
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.000	0.999	0.001
M53.99 Dorsopathy, unspecified (Site unspecified)	0.000	0.999	0.001
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.000	0.999	0.001
M53.96 Dorsopathy, unspecified (Lumbar region)	0.000	0.999	0.001
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M53.94 Dorsopathy, unspecified (Thoracic region)	0.000	0.999	0.001
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M53.92 Dorsopathy, unspecified (Cervical region)	0.000	0.999	0.001
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.000	0.999	0.001
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.999	0.001
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.999	0.001
H53.4 Visual field defects	0.001	0.999	0.000
M50.9 Cervical disk disorder, unspecified	0.000	0.999	0.001
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.001	0.999	0.000
X49.09 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Home; During unspecified activity	0.000	0.999	0.001
X49.48 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Street and highway;While engaged in other specified activities	0.000	0.999	0.001
C78.0 Secondary malignant neoplasm of lung	0.000	0.999	0.001
H61.9 Disorder of external ear, unspecified	0.000	0.999	0.001
I27.9 Pulmonary heart disease, unspecified	0.001	0.999	0.000
K38.8 Other specified diseases of appendix	0.000	0.999	0.001
S22.3 Fracture of rib	0.000	0.999	0.001
E34.8 Other specified endocrine disorders	0.000	0.999	0.001
E74.3 Other disorders of intestinal carbohydrate absorption	0.001	0.999	0.000
H60.9 Otitis externa, unspecified	0.000	0.999	0.001
I12.9 Hypertensive renal disease without renal failure	0.000	0.999	0.001
M53.89 Other specified dorsopathies (Site unspecified)	0.000	0.999	0.001
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M53.87 Other specified dorsopathies (Lumbosacral region)	0.000	0.999	0.001
M53.86 Other specified dorsopathies (Lumbar region)	0.000	0.999	0.001
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.000	0.999	0.001
M53.84 Other specified dorsopathies (Thoracic region)	0.000	0.999	0.001
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.000	0.999	0.001
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.000	0.999	0.001
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.000	0.999	0.001
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.001	0.999	0.000
N13.6 Pyonephrosis	0.001	0.999	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.001	0.999	0.000
M53.29 Spinal instabilities (Site unspecified)	0.000	0.999	0.001
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M53.27 Spinal instabilities (Lumbosacral region)	0.000	0.999	0.001
M53.25 Spinal instabilities (Thoracolumbar region)	0.000	0.999	0.001
M53.24 Spinal instabilities (Thoracic region)	0.000	0.999	0.001
M53.23 Spinal instabilities (Cervicothoracic region)	0.000	0.999	0.001
M53.22 Spinal instabilities (Cervical region)	0.000	0.999	0.001
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.000	0.999	0.001
M53.20 Spinal instabilities (Multiple sites in spine)	0.000	0.999	0.001
F22.0 Delusional disorder	0.001	0.999	0.000
N87.1 Moderate cervical dysplasia	0.001	0.999	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.999	0.000
S42 Fracture of shoulder and upper arm	0.000	0.999	0.001
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.001	0.999	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.001	0.999	0.000
D50.8 Other iron deficiency anaemias	0.001	0.999	0.000
E11.3 With ophthalmic complications	0.001	0.999	0.000
E11.0 With coma	0.000	0.999	0.001
S22.31 Fracture of rib (open)	0.000	0.999	0.001
W44.0 Home	0.001	0.999	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.001	0.999	0.000
M53.82 Other specified dorsopathies (Cervical region)	0.000	0.999	0.001
S52.80 Fracture of other parts of forearm (closed)	0.001	0.999	0.000
C62.9 Testis, unspecified	0.000	0.999	0.001
K57.1 Diverticular disease of small intestine without perforation or abscess	0.001	0.999	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.001	0.999	0.000
Y40.9 Systemic antibiotic, unspecified	0.001	0.999	0.000
M53.26 Spinal instabilities (Lumbar region)	0.000	0.999	0.001
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.999	0.001
D17.7 Benign lipomatous neoplasm of other sites	0.000	0.999	0.001
L93.0 Discoid lupus erythematosus	0.001	0.999	0.000
O03.9 Complete or unspecified, without complication	0.001	0.999	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.999	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.001	0.999	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.999	0.001
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
Y40.8 Other systemic antibiotics	0.001	0.999	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.001	0.999	0.000
Z99.4 Dependence on artificial heart	0.001	0.999	0.000
Z99.0 Dependence on aspirator	0.001	0.999	0.000
B18 Chronic viral hepatitis	0.000	0.999	0.001
E34 Other endocrine disorders	0.000	0.999	0.001
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.001	0.999	0.000
B15.9 Hepatitis A without hepatic coma	0.001	0.999	0.000
C45.9 Mesothelioma, unspecified	0.000	0.999	0.001
C83.1 Small cleaved cell (diffuse)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations