TreeWAS – Variant ID: rs6488898

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R49.0 Dysphonia	0.000	0.947	0.053
D05.9 Carcinoma in situ of breast, unspecified	0.025	0.975	0.000
R49 Voice disturbances	0.000	0.976	0.024
D05.1 Intraductal carcinoma in situ	0.022	0.978	0.000
D05 Carcinoma in situ of breast	0.021	0.979	0.000
R49.8 Other and unspecified voice disturbances	0.000	0.982	0.017
R49.2 Hypernasality and hyponasality	0.000	0.982	0.017
R49.1 Aphonia	0.000	0.984	0.016
D05.0 Lobular carcinoma in situ	0.015	0.985	0.000
D05.7 Other carcinoma in situ of breast	0.014	0.985	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.990	0.010
Z09.8 Follow-up examination after other treatment for other conditions	0.000	0.993	0.007
I38 Endocarditis, valve unspecified	0.000	0.993	0.007
R47-R49 Symptoms and signs involving speech and voice	0.000	0.993	0.007
S82.1 Fracture of upper end of tibia	0.000	0.993	0.006
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.000	0.994	0.006
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.994	0.006
U80.1 Methicillin resistant agent	0.006	0.994	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.995	0.005
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.005	0.995	0.000
R48.0 Dyslexia and alexia	0.000	0.995	0.005
U80 Agent resistant to penicillin and related antibiotics	0.005	0.995	0.000
S82.11 Fracture of upper end of tibia (open)	0.000	0.995	0.004
S82 Fracture of lower leg, including ankle	0.000	0.995	0.005
S82.3 Fracture of lower end of tibia	0.000	0.995	0.004
R48.8 Other and unspecified symbolic dysfunctions	0.000	0.996	0.004
R48.2 Apraxia	0.000	0.996	0.004
R48.1 Agnosia	0.000	0.996	0.004
Y57.9 Drug or medicament, unspecified	0.000	0.996	0.004
U80.0 Penicillin resistant agent	0.004	0.996	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.996	0.004
S82.6 Fracture of lateral malleolus	0.000	0.996	0.004
U80.8 Agent resistant to other penicillin-related antibiotic	0.004	0.996	0.000
M19.0 Primary arthrosis of other joints	0.004	0.996	0.000
S82.31 Fracture of lower end of tibia (open)	0.000	0.996	0.004
N95.2 Postmenopausal atrophic vaginitis	0.004	0.996	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.996	0.004
Y57 Other and unspecified drugs and medicaments	0.000	0.996	0.004
M19.00 Primary arthrosis of other joints (Multiple sites)	0.004	0.996	0.000
Y57.8 Other drugs and medicaments	0.000	0.996	0.004
S82.9 Fracture of lower leg, part unspecified	0.000	0.996	0.004
M19.02 Primary arthrosis of other joints (Upper arm)	0.004	0.996	0.000
S82.5 Fracture of medial malleolus	0.000	0.996	0.003
S82.61 Fracture of lateral malleolus (open)	0.000	0.996	0.003
M19.01 Primary arthrosis of other joints (Shoulder region)	0.003	0.996	0.000
S82.0 Fracture of patella	0.000	0.997	0.003
S82.7 Multiple fractures of lower leg	0.000	0.997	0.003
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.997	0.003
M19.08 Primary arthrosis of other joints (Other)	0.003	0.997	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.003	0.997	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.003	0.997	0.000
Y57.5 X-ray contrast media	0.000	0.997	0.003
R47 Speech disturbances, not elsewhere classified	0.000	0.997	0.003
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.003	0.997	0.000
S82.4 Fracture of fibula alone	0.000	0.997	0.003
M16.9 Coxarthrosis, unspecified	0.003	0.997	0.000
S82.2 Fracture of shaft of tibia	0.000	0.997	0.003
Y57.7 Vitamins, not elsewhere classified	0.000	0.997	0.003
Y57.4 Pharmaceutical excipients	0.000	0.997	0.003
Y57.3 Alcohol deterrents	0.000	0.997	0.003
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.997	0.003
Y57.1 Lipotropic drugs	0.000	0.997	0.003
Y57.0 Appetite depressants [anorectics]	0.000	0.997	0.003
Y57.6 Other diagnostic agents	0.000	0.997	0.003
S82.51 Fracture of medial malleolus (open)	0.000	0.997	0.003
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.997	0.003
M19.09 Primary arthrosis of other joints (Site unspecified)	0.003	0.997	0.000
H91.9 Hearing loss, unspecified	0.000	0.997	0.003
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.997	0.003
M19.03 Primary arthrosis of other joints (Forearm)	0.003	0.997	0.000
S82.01 Fracture of patella (open)	0.000	0.997	0.003
S82.50 Fracture of medial malleolus (closed)	0.000	0.997	0.003
S81.0 Open wound of knee	0.003	0.997	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.003	0.997	0.000
S82.71 Multiple fractures of lower leg (open)	0.000	0.997	0.002
S82.8 Fractures of other parts of lower leg	0.000	0.997	0.003
Y86 Sequelae of other accidents	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.000	0.997	0.003
Y49.5 Other antipsychotics and neuroleptics	0.000	0.997	0.003
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.003	0.997	0.000
S82.70 Multiple fractures of lower leg (closed)	0.000	0.997	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.003	0.997	0.000
S82.41 Fracture of fibula alone (open)	0.000	0.997	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.997	0.002
J38.7 Other diseases of larynx	0.000	0.997	0.003
S82.21 Fracture of shaft of tibia (open)	0.000	0.997	0.002
M19.1 Posttraumatic arthrosis of other joints	0.002	0.997	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.997	0.002
H92.0 Otalgia	0.000	0.998	0.002
R47.0 Dysphasia and aphasia	0.000	0.998	0.002
M19 Other arthrosis	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.000	0.998	0.002
H91 Other hearing loss	0.000	0.998	0.002
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
D00-D09 In situ neoplasms	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.000	0.998	0.002
Y54.3 Benzothiadiazine derivatives	0.000	0.998	0.002
S82.81 Fractures of other parts of lower leg (open)	0.000	0.998	0.002
J38.0 Paralysis of vocal cords and larynx	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
R47.1 Dysarthria and anarthria	0.000	0.998	0.002
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.998	0.002
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.002	0.998	0.000
S82.86 Maisonneuve's fracture	0.000	0.998	0.002
H91.1 Presbycusis	0.000	0.998	0.002
J38.3 Other diseases of vocal cords	0.000	0.998	0.002
M19.8 Other specified arthrosis	0.002	0.998	0.000
D09 Carcinoma in situ of other and unspecified sites	0.002	0.998	0.000
R02 Gangrene, not elsewhere classified	0.000	0.998	0.002
D09.0 Bladder	0.002	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.000	0.998	0.002
H91.2 Sudden idiopathic hearing loss	0.000	0.998	0.002
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.998	0.002
U50 Level of care administered to neonates	0.002	0.998	0.000
U07 Emergency use of U07	0.002	0.998	0.000
U06 Emergency use of U06	0.002	0.998	0.000
U04 Severe acute respiratory syndrome [SARS]	0.002	0.998	0.000
U52 First in a series of a regular day/night admissions	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.998	0.002
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
M19.2 Other secondary arthrosis	0.002	0.998	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.002	0.998	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.998	0.002
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.998	0.002
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.002	0.998	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.002	0.998	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.002	0.998	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.002	0.998	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.000	0.998	0.002
Y52.7 Peripheral vasodilators	0.000	0.998	0.002
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.998	0.002
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
D02 Carcinoma in situ of middle ear and respiratory system	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
D01 Carcinoma in situ of other and unspecified digestive organs	0.002	0.998	0.000
I26 Pulmonary embolism	0.002	0.998	0.000
M16 Coxarthrosis [arthrosis of hip]	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.000	0.998	0.002
Y49.7 Psychostimulants with abuse potential	0.000	0.998	0.002
Y49.6 Psychodysleptics [hallucinogens]	0.000	0.998	0.002
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
M19.87 Other specified arthrosis (Ankle and foot)	0.002	0.998	0.000
H91.0 Ototoxic hearing loss	0.000	0.998	0.002
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
M18 Arthrosis of first carpometacarpal joint	0.000	0.998	0.002
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
M19.89 Other specified arthrosis (Site unspecified)	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.998	0.002
U51 Admission status on psychiatric patients	0.002	0.998	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.002	0.998	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.002	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
L71.9 Rosacea, unspecified	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.002	0.998	0.000
T92.1 Sequelae of fracture of arm	0.002	0.998	0.000
Y58 Bacterial vaccines	0.000	0.998	0.002
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.002
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.002	0.998	0.000
Y43.3 Other antineoplastic drugs	0.000	0.998	0.002
Y49.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
D09.1 Other and unspecified urinary organs	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.000	0.998	0.002
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
Y51.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
Y51.0 Anticholinesterase agents	0.000	0.998	0.002
Y54.7 Agents affecting calcification	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
M19.86 Other specified arthrosis (Lower leg)	0.002	0.998	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.002	0.998	0.000
M19.84 Other specified arthrosis (Hand)	0.002	0.998	0.000
M19.83 Other specified arthrosis (Forearm)	0.002	0.998	0.000
M19.82 Other specified arthrosis (Upper arm)	0.002	0.998	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.002	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.002	0.998	0.000
U81.0 Vancomycin resistant agent	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
M19.21 Other secondary arthrosis (Shoulder region)	0.002	0.998	0.000
M19.88 Other specified arthrosis (Other)	0.002	0.998	0.000
D09.3 Thyroid and other endocrine glands	0.002	0.998	0.000
D09.2 Eye	0.002	0.998	0.000
M16.1 Other primary coxarthrosis	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.998	0.002
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.000	0.998	0.002
Y48 Anaesthetics and therapeutic gases	0.000	0.998	0.002
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
M19.27 Other secondary arthrosis (Ankle and foot)	0.002	0.998	0.000
N32.0 Bladder-neck obstruction	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.998	0.002
Y43 Primarily systemic agents	0.000	0.998	0.002
M19.29 Other secondary arthrosis (Site unspecified)	0.002	0.998	0.000
M19.28 Other secondary arthrosis (Other)	0.002	0.998	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.002	0.998	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.002	0.998	0.000
M19.24 Other secondary arthrosis (Hand)	0.002	0.998	0.000
M19.23 Other secondary arthrosis (Forearm)	0.002	0.998	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.002	0.998	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.002	0.998	0.000
M16.3 Other dysplastic coxarthrosis	0.002	0.998	0.000
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.002	0.998	0.000
U06.9 Emergency use of U06.9	0.002	0.998	0.000
U06.8 Emergency use of U06.8	0.002	0.998	0.000
U06.7 Emergency use of U06.7	0.002	0.998	0.000
U06.6 Emergency use of U06.6	0.002	0.998	0.000
U06.5 Emergency use of U06.5	0.002	0.998	0.000
U06.4 Emergency use of U06.4	0.002	0.998	0.000
U06.3 Emergency use of U06.3	0.002	0.998	0.000
U06.2 Emergency use of U06.2	0.002	0.998	0.000
U06.1 Emergency use of U06.1	0.002	0.998	0.000
U06.0 Emergency use of U06.0	0.002	0.998	0.000
U07.9 Emergency use of U07.9	0.002	0.998	0.000
U07.8 Emergency use of U07.8	0.002	0.998	0.000
U07.7 Emergency use of U07.7	0.002	0.998	0.000
U07.6 Emergency use of U07.6	0.002	0.998	0.000
U07.5 Emergency use of U07.5	0.002	0.998	0.000
U07.4 Emergency use of U07.4	0.002	0.998	0.000
U07.3 Emergency use of U07.3	0.002	0.998	0.000
U07.2 Emergency use of U07.2	0.002	0.998	0.000
U07.1 Emergency use of U07.1	0.002	0.998	0.000
U07.0 Emergency use of U07.0	0.002	0.998	0.000
U50.9 Inquest Adjourned Death	0.002	0.998	0.000
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.002	0.998	0.000
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.002	0.998	0.000
U50.1 Level of care administered to neonates (Special Care)	0.002	0.998	0.000
U50.0 Level of care administered to neonates (Normal Care)	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
Y54.9 Mineral salts, not elsewhere classified	0.000	0.998	0.002
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.998	0.002
E66.9 Obesity, unspecified	0.002	0.998	0.000
J38.6 Stenosis of larynx	0.000	0.998	0.002
Y50.9 Central nervous system stimulant, unspecified	0.000	0.998	0.002
Y50.8 Other central nervous system stimulants	0.000	0.998	0.002
Y50.1 Opioid receptor antagonists	0.000	0.998	0.002
Y50.0 Analeptics	0.000	0.998	0.002
Y54.0 Mineralocorticoids	0.000	0.998	0.002
H91.8 Other specified hearing loss	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.002
Y55.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
D01.0 Colon	0.002	0.998	0.000
M17.1 Other primary gonarthrosis	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.000	0.998	0.002
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
C71.9 Brain, unspecified	0.002	0.998	0.000
D01.5 Liver, gallbladder and bile ducts	0.002	0.998	0.000
D02.0 Larynx	0.002	0.998	0.000
J38.2 Nodules of vocal cords	0.000	0.998	0.002
Y48.3 Local anaesthetics	0.000	0.998	0.002
D02.4 Respiratory system, unspecified	0.001	0.998	0.000
D02.3 Other parts of respiratory system	0.001	0.998	0.000
D02.2 Bronchus and lung	0.001	0.998	0.000
D02.1 Trachea	0.001	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
Y42.7 Androgens and anabolic congeners	0.000	0.998	0.002
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.000	0.998	0.001
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.002
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.998	0.002
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
M16.4 Posttraumatic coxarthrosis, bilateral	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
Y53.2 Stimulant laxatives	0.000	0.998	0.002
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.998	0.002
M24.17 Other articular cartilage disorders (Ankle and foot)	0.002	0.998	0.000
D01.9 Digestive organ, unspecified	0.001	0.998	0.000
D01.7 Other specified digestive organs	0.001	0.998	0.000
D01.4 Other and unspecified parts of intestine	0.001	0.998	0.000
D01.1 Rectosigmoid junction	0.001	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.001	0.998	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.001	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.000	0.998	0.002
D01.2 Rectum	0.001	0.998	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.998	0.001
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.001
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.001
U51.0 Not Previously admitted to a psyciatric hospital	0.001	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.001
Y55.5 Anticommon cold drugs	0.000	0.998	0.001
Y55.3 Antitussives	0.000	0.998	0.001
Y55.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.001
J84 Other interstitial pulmonary diseases	0.000	0.998	0.002
G50.0 Trigeminal neuralgia	0.002	0.998	0.000
U51.2 Previously admitted to a psychiatric hospital of another provider	0.001	0.998	0.000
Y58.0 BCG vaccine	0.000	0.998	0.001
C71.3 Parietal lobe	0.002	0.998	0.000
M24.1 Other articular cartilage disorders	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.000	0.998	0.001
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.000	0.998	0.001
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.000	0.998	0.001
Y58.5 Diphtheria vaccine	0.000	0.998	0.001
Y58.4 Tetanus vaccine	0.000	0.998	0.001
Y58.3 Plague vaccine	0.000	0.998	0.001
Y58.2 Cholera vaccine	0.000	0.998	0.001
Y58.1 Typhoid and paratyphoid vaccine	0.000	0.998	0.001
Y59.3 Immunoglobulin	0.000	0.998	0.001
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.001	0.998	0.000
C71.1 Frontal lobe	0.002	0.998	0.000
H40.9 Glaucoma, unspecified	0.002	0.998	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.001	0.998	0.001
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.001
Y53.7 Emetics	0.000	0.998	0.001
Y53.5 Digestants	0.000	0.998	0.001
Y53.0 Histamine H2-receptor antagonists	0.000	0.998	0.001
Y55.4 Expectorants	0.000	0.998	0.001
Y55.0 Oxytocic drugs	0.000	0.998	0.001
Y59.9 Vaccine or biological substance, unspecified	0.000	0.998	0.001
Y59.8 Other specified vaccines and biological substances	0.000	0.998	0.001
Y59.2 Protozoal vaccines	0.000	0.998	0.001
Y59.1 Rickettsial vaccines	0.000	0.998	0.001
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.998	0.002
D01.3 Anus and anal canal	0.001	0.998	0.000
Y43.2 Antineoplastic natural products	0.000	0.998	0.001
Y53.3 Saline and osmotic laxatives	0.000	0.998	0.001
M16.6 Other secondary coxarthrosis, bilateral	0.001	0.998	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.001
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.001
Y48.5 Therapeutic gases	0.000	0.998	0.001
Y48.1 Parenteral anaesthetics	0.000	0.998	0.001
Y48.0 Inhaled anaesthetics	0.000	0.998	0.001
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.001
Y56.9 Topical agent, unspecified	0.000	0.998	0.001
Y56.8 Other topical agents	0.000	0.998	0.001
Y56.7 Dental drugs, topically applied	0.000	0.998	0.001
Y56.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.001
Y56.5 Ophthalmological drugs and preparations	0.000	0.998	0.001
Y56.2 Local astringents and local detergents	0.000	0.998	0.001
Y56.1 Antipruritics	0.000	0.998	0.001
Y59.0 Viral vaccines	0.000	0.998	0.001
C71 Malignant neoplasm of brain	0.002	0.998	0.000
D06 Carcinoma in situ of cervix uteri	0.001	0.998	0.000
H90-H95 Other disorders of ear	0.000	0.998	0.002
D00.2 Stomach	0.001	0.998	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.000	0.998	0.001
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.998	0.001
Y43.6 Enzymes, not elsewhere classified	0.000	0.998	0.001
Y43.5 Acidifying and alkalising agents	0.000	0.998	0.001
T92 Sequelae of injuries of upper limb	0.002	0.998	0.000
C71.2 Temporal lobe	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.998	0.002
M16.5 Other posttraumatic coxarthrosis	0.001	0.998	0.000
Y42.2 Antithyroid drugs	0.000	0.998	0.001
Y53.6 Antidiarrhoeal drugs	0.000	0.998	0.001
Y87.1 Sequelae of assault	0.001	0.998	0.000
D03 Melanoma in situ	0.002	0.998	0.000
D00.1 Oesophagus	0.001	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.002	0.998	0.000
H92.2 Otorrhagia	0.000	0.998	0.001
H93.1 Tinnitus	0.000	0.998	0.002
J38.5 Laryngeal spasm	0.000	0.998	0.001
Y46.4 Iminostilbenes	0.000	0.998	0.001
Y53.4 Other laxatives	0.000	0.998	0.001
Y54.5 Other diuretics	0.000	0.998	0.001
H93 Other disorders of ear, not elsewhere classified	0.000	0.998	0.002
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.001
Y41.1 Antimycobacterial drugs	0.000	0.998	0.001
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.001
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.001
Y41.4 Anthelminthics	0.000	0.998	0.001
Y41.3 Other antiprotozoal drugs	0.000	0.998	0.001
Y42.4 Oral contraceptives	0.000	0.998	0.001
Z49.1 Extracorporeal dialysis	0.001	0.998	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.001	0.998	0.000
M16.0 Primary coxarthrosis, bilateral	0.001	0.998	0.000
Y41.5 Antiviral drugs	0.000	0.998	0.001
Y45.5 4-Aminophenol derivatives	0.001	0.998	0.000
Y45.2 Propionic acid derivatives	0.001	0.998	0.000
Y46.8 Antispasticity drugs	0.000	0.998	0.001
Y46.3 Deoxybarbiturates	0.000	0.998	0.001
Y46.1 Oxazolidinediones	0.000	0.998	0.001
Y46.0 Succinimides	0.000	0.998	0.001
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.998	0.001
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.998	0.001
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.998	0.001
Y47.4 Bromine compounds	0.000	0.998	0.001
Y47.3 Paraldehyde	0.000	0.998	0.001
Y47.2 Chloral derivatives	0.000	0.998	0.001
Y47.0 Barbiturates, not elsewhere classified	0.000	0.998	0.001
M24.14 Other articular cartilage disorders (Hand)	0.001	0.998	0.000
Y41.0 Sulphonamides	0.000	0.998	0.001
Y42.1 Thyroid hormones and substitutes	0.000	0.998	0.001
Y45.4 Antirheumatics	0.001	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.000	0.998	0.001
Y48.4 Anaesthetic, unspecified	0.000	0.998	0.001
Y48.2 Other and unspecified general anaesthetics	0.000	0.998	0.001
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.001
D04 Carcinoma in situ of skin	0.001	0.998	0.000
C71.5 Cerebral ventricle	0.001	0.999	0.000
D00.0 Lip, oral cavity and pharynx	0.001	0.999	0.000
D04.6 Skin of upper limb, including shoulder	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.000	0.999	0.001
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.999	0.001
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.999	0.001
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.001	0.999	0.000
Y45.8 Other analgesics and antipyretics	0.001	0.999	0.000
Y87.2 Sequelae of events of undetermined intent	0.001	0.999	0.000
S81 Open wound of lower leg	0.001	0.999	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.001	0.999	0.000
M24.18 Other articular cartilage disorders (Other)	0.001	0.999	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.001	0.999	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.001	0.999	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.999	0.001
D04.4 Skin of scalp and neck	0.001	0.999	0.000
Y43.1 Antineoplastic antimetabolites	0.000	0.999	0.001
Y44 Agents primarily affecting blood constituents	0.000	0.999	0.001
D03.6 Melanoma in situ of upper limb, including shoulder	0.001	0.999	0.000
D03.0 Melanoma in situ of lip	0.001	0.999	0.000
D06.1 Exocervix	0.001	0.999	0.000
S81.9 Open wound of lower leg, part unspecified	0.001	0.999	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.001	0.999	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.001	0.999	0.000
Y46.5 Valproic acid	0.000	0.999	0.001
Y40 Systemic antibiotics	0.000	0.999	0.001
C71.8 Overlapping lesion of brain	0.001	0.999	0.000
C71.6 Cerebellum	0.001	0.999	0.000
D46.2 Refractory anaemia with excess of blasts	0.000	0.999	0.001
H93.2 Other abnormal auditory perceptions	0.000	0.999	0.001
Y43.4 Immunosuppressive agents	0.000	0.999	0.001
Y46.6 Other and unspecified antiepileptics	0.000	0.999	0.001
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.999	0.001
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.001	0.999	0.000
D03.8 Melanoma in situ of other sites	0.001	0.999	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.001	0.999	0.000
D06.7 Other parts of cervix	0.001	0.999	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.001	0.999	0.000
D03.9 Melanoma in situ, unspecified	0.001	0.999	0.000
D06.0 Endocervix	0.001	0.999	0.000
H93.3 Disorders of acoustic nerve	0.000	0.999	0.001
J84.0 Alveolar and parietoalveolar conditions	0.000	0.999	0.001
Y46.2 Hydantoin derivatives	0.000	0.999	0.001
C71.7 Brain stem	0.001	0.999	0.000
D04.9 Skin, unspecified	0.001	0.999	0.000
H93.0 Degenerative and vascular disorders of ear	0.000	0.999	0.001
O24.4 Diabetes mellitus arising in pregnancy	0.001	0.999	0.000
S81.7 Multiple open wounds of lower leg	0.001	0.999	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.001	0.999	0.000
Y40.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
Z49.2 Other dialysis	0.001	0.999	0.000
D35.2 Pituitary gland	0.000	0.999	0.001
D46.4 Refractory anaemia, unspecified	0.000	0.999	0.001
J84.8 Other specified interstitial pulmonary diseases	0.000	0.999	0.001
K57.2 Diverticular disease of large intestine with perforation and abscess	0.001	0.999	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.001	0.999	0.000
Y47.1 Benzodiazepines	0.000	0.999	0.001
D46 Myelodysplastic syndromes	0.000	0.999	0.001
M24.13 Other articular cartilage disorders (Forearm)	0.001	0.999	0.000
C71.4 Occipital lobe	0.001	0.999	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.001	0.999	0.000
D03.4 Melanoma in situ of scalp and neck	0.001	0.999	0.000
D04.8 Skin of other sites	0.001	0.999	0.000
H93.8 Other specified disorders of ear	0.000	0.999	0.001
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.001	0.999	0.000
T92.0 Sequelae of open wound of upper limb	0.001	0.999	0.000
Y43.0 Antiallergic and antiemetic drugs	0.000	0.999	0.001
D03.1 Melanoma in situ of eyelid, including canthus	0.001	0.999	0.000
D04.0 Skin of lip	0.001	0.999	0.000
D46.1 Refractory anaemia with sideroblasts	0.000	0.999	0.001
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.001	0.999	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.999	0.001
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.999	0.001
R07.3 Other chest pain	0.001	0.999	0.000
Y44.6 Natural blood and blood products	0.000	0.999	0.001
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.999	0.001
C71.0 Cerebrum, except lobes and ventricles	0.001	0.999	0.000
D04.1 Skin of eyelid, including canthus	0.001	0.999	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.999	0.001
J38.4 Oedema of larynx	0.000	0.999	0.001
Y40.2 Chloramphenicol group	0.000	0.999	0.001
Y44.9 Other and unspecified agents affecting blood constituents	0.000	0.999	0.001
Y44.7 Plasma substitutes	0.000	0.999	0.001
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.000	0.999	0.001
Y45.1 Salicylates	0.001	0.999	0.000
Y87.0 Sequelae of intentional self-harm	0.001	0.999	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.000	0.999	0.001
D46.7 Other myelodysplastic syndromes	0.000	0.999	0.001
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.999	0.001
H92.1 Otorrhoea	0.000	0.999	0.001
H93.9 Disorder of ear, unspecified	0.000	0.999	0.001
L71.1 Rhinophyma	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations