TreeWAS – Variant ID: rs6489785

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.952	0.048
E03 Other hypothyroidism	0.000	0.982	0.018
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.016	0.984	0.000
E03.8 Other specified hypothyroidism	0.000	0.986	0.014
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.986	0.013
G83.4 Cauda equina syndrome	0.013	0.987	0.000
E03.5 Myxoedema coma	0.000	0.987	0.013
E03.4 Atrophy of thyroid (acquired)	0.000	0.987	0.013
E03.3 Postinfectious hypothyroidism	0.000	0.987	0.013
Z88.1 Personal history of allergy to other antibiotic agents	0.013	0.987	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.989	0.011
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.989	0.011
E27.4 Other and unspecified adrenocortical insufficiency	0.009	0.991	0.000
G83 Other paralytic syndromes	0.009	0.991	0.000
J92.9 Pleural plaque without asbestos	0.008	0.992	0.000
G83.8 Other specified paralytic syndromes	0.008	0.992	0.000
K50.0 Crohn's disease of small intestine	0.008	0.992	0.000
G83.1 Monoplegia of lower limb	0.008	0.992	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.992	0.008
K50.9 Crohn's disease, unspecified	0.008	0.992	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.992	0.008
S60.8 Other superficial injuries of wrist and hand	0.000	0.993	0.007
G83.3 Monoplegia, unspecified	0.007	0.993	0.000
G83.5 Locked-in syndrome	0.006	0.993	0.000
G83.0 Diplegia of upper limbs	0.006	0.993	0.000
K50 Crohn's disease [regional enteritis]	0.006	0.994	0.000
M35.0 Sicca syndrome [Sjogren]	0.006	0.994	0.000
G83.2 Monoplegia of upper limb	0.006	0.994	0.000
E27 Other disorders of adrenal gland	0.006	0.994	0.000
M35 Other systemic involvement of connective tissue	0.006	0.994	0.000
M35.3 Polymyalgia rheumatica	0.006	0.994	0.000
E27.2 Addisonian crisis	0.005	0.995	0.000
M45 Ankylosing spondylitis	0.000	0.995	0.005
E27.3 Drug-induced adrenocortical insufficiency	0.005	0.995	0.000
M35.8 Other specified systemic involvement of connective tissue	0.005	0.995	0.000
Z00.5 Examination of potential donor of organ and tissue	0.000	0.995	0.005
G83.9 Paralytic syndrome, unspecified	0.005	0.995	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.995	0.005
E27.1 Primary adrenocortical insufficiency	0.005	0.995	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.005	0.995	0.000
M35.2 Behcet's disease	0.005	0.995	0.000
E27.5 Adrenomedullary hyperfunction	0.004	0.995	0.000
E27.0 Other adrenocortical overactivity	0.004	0.995	0.000
E27.8 Other specified disorders of adrenal gland	0.004	0.996	0.000
K50.1 Crohn's disease of large intestine	0.004	0.996	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.996	0.004
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.996	0.004
M35.9 Systemic involvement of connective tissue, unspecified	0.004	0.996	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.004	0.996	0.000
M35.5 Multifocal fibrosclerosis	0.004	0.996	0.000
M35.1 Other overlap syndromes	0.004	0.996	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.996	0.004
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.996	0.004
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.996	0.004
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.996	0.004
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.996	0.004
K50.8 Other Crohn's disease	0.004	0.996	0.000
M35.7 Hypermobility syndrome	0.004	0.996	0.000
J32.0 Chronic maxillary sinusitis	0.004	0.996	0.000
F22.0 Delusional disorder	0.000	0.996	0.004
O02.1 Missed abortion	0.000	0.997	0.003
S89.9 Unspecified injury of lower leg	0.000	0.997	0.003
K26.4 Chronic or unspecified with haemorrhage	0.003	0.997	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.003	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.003	0.997	0.000
D75.2 Essential thrombocytosis	0.000	0.997	0.003
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.997	0.003
I78.1 Naevus, nonneoplastic	0.003	0.997	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.003	0.997	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.997	0.003
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.003	0.997	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.997	0.003
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.997	0.003
M95.0 Acquired deformity of nose	0.000	0.997	0.003
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.997	0.003
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.997	0.003
H11.3 Conjunctival haemorrhage	0.003	0.997	0.000
I78 Diseases of capillaries	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.003	0.997	0.000
D23.3 Skin of other and unspecified parts of face	0.000	0.997	0.003
R09.0 Asphyxia	0.000	0.997	0.003
I78.8 Other diseases of capillaries	0.002	0.997	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.998	0.002
F43.1 Posttraumatic stress disorder	0.000	0.998	0.002
G97.1 Other reaction to spinal and lumbar puncture	0.002	0.998	0.000
N95.1 Menopausal and female climacteric states	0.000	0.998	0.002
C71.2 Temporal lobe	0.000	0.998	0.002
N82.3 Fistula of vagina to large intestine	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.000	0.998	0.002
K75.8 Other specified inflammatory liver diseases	0.002	0.998	0.000
K75.0 Abscess of liver	0.002	0.998	0.000
J92 Pleural plaque	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
K75.9 Inflammatory liver disease, unspecified	0.002	0.998	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.998	0.002
I78.9 Disease of capillaries, unspecified	0.002	0.998	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
N76.4 Abscess of vulva	0.000	0.998	0.002
N85.6 Intra-uterine synechiae	0.000	0.998	0.002
F43.9 Reaction to severe stress, unspecified	0.000	0.998	0.002
N82.1 Other female urinary-genital tract fistulae	0.002	0.998	0.000
K76.9 Liver disease, unspecified	0.000	0.998	0.002
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.998	0.002
M76.67 Achilles tendinitis (Ankle and foot)	0.000	0.998	0.002
G97.0 Cerebrospinal fluid leak from spinal puncture	0.002	0.998	0.000
T21.3 Burn of third degree of trunk	0.002	0.998	0.000
O80.9 Single spontaneous delivery, unspecified	0.002	0.998	0.000
R09.3 Abnormal sputum	0.000	0.998	0.002
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.998	0.002
F43.0 Acute stress reaction	0.000	0.998	0.002
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.998	0.002
K75 Other inflammatory liver diseases	0.002	0.998	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.002	0.998	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
M95.3 Acquired deformity of neck	0.000	0.998	0.002
T21.2 Burn of second degree of trunk	0.002	0.998	0.000
T21.0 Burn of unspecified degree of trunk	0.002	0.998	0.000
E26.0 Primary hyperaldosteronism	0.002	0.998	0.000
F43 Reaction to severe stress, and adjustment disorders	0.000	0.998	0.002
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.998	0.002
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
N82 Fistulae involving female genital tract	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
J32.8 Other chronic sinusitis	0.002	0.998	0.000
T21 Burn and corrosion of trunk	0.002	0.998	0.000
N82.4 Other female intestinal-genital tract fistulae	0.002	0.998	0.000
D23.2 Skin of ear and external auricular canal	0.000	0.998	0.002
E07.9 Disorder of thyroid, unspecified	0.000	0.998	0.002
H52.3 Anisometropia and aniseikonia	0.000	0.998	0.002
T78.4 Allergy, unspecified	0.002	0.998	0.000
Z47.8 Other specified orthopaedic follow-up care	0.000	0.998	0.002
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.998	0.002
D12.4 Descending colon	0.000	0.998	0.002
E06 Thyroiditis	0.001	0.998	0.000
G82 Paraplegia and tetraplegia	0.002	0.998	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.002	0.998	0.000
F22 Persistent delusional disorders	0.000	0.998	0.002
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.998	0.002
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.998	0.001
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.998	0.002
M95.4 Acquired deformity of chest and rib	0.000	0.998	0.002
O80.0 Spontaneous vertex delivery	0.002	0.998	0.000
K75.2 Nonspecific reactive hepatitis	0.002	0.998	0.000
K75.1 Phlebitis of portal vein	0.002	0.998	0.000
E07 Other disorders of thyroid	0.000	0.998	0.002
O02 Other abnormal products of conception	0.000	0.998	0.002
F43.8 Other reactions to severe stress	0.000	0.998	0.001
N82.9 Female genital tract fistula, unspecified	0.002	0.998	0.000
N82.0 Vesicovaginal fistula	0.002	0.998	0.000
R09.2 Respiratory arrest	0.000	0.998	0.002
T21.1 Burn of first degree of trunk	0.002	0.998	0.000
S60 Superficial injury of wrist and hand	0.000	0.998	0.002
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.000	0.998	0.001
M95.8 Other specified acquired deformities of musculoskeletal system	0.000	0.998	0.001
M95.5 Acquired deformity of pelvis	0.000	0.998	0.001
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.998	0.002
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.998	0.002
M95.1 Cauliflower ear	0.000	0.998	0.001
N82.2 Fistula of vagina to small intestine	0.001	0.998	0.000
E06.5 Other chronic thyroiditis	0.001	0.998	0.000
E26 Hyperaldosteronism	0.002	0.998	0.000
T21.7 Corrosion of third degree of trunk	0.001	0.998	0.000
T21.6 Corrosion of second degree of trunk	0.001	0.998	0.000
T21.5 Corrosion of first degree of trunk	0.001	0.998	0.000
T21.4 Corrosion of unspecified degree of trunk	0.001	0.998	0.000
E00-E07 Disorders of thyroid gland	0.000	0.998	0.002
E06.1 Subacute thyroiditis	0.001	0.998	0.000
M95.2 Other acquired deformity of head	0.000	0.998	0.001
N92.4 Excessive bleeding in the premenopausal period	0.002	0.998	0.000
E06.4 Drug-induced thyroiditis	0.001	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.998	0.000
E06.0 Acute thyroiditis	0.001	0.998	0.000
G82.3 Flaccid tetraplegia	0.001	0.998	0.000
G82.0 Flaccid paraplegia	0.001	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.998	0.002
O66.2 Obstructed labour due to unusually large foetus	0.000	0.998	0.001
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.998	0.001
O66 Other obstructed labour	0.000	0.998	0.002
E07.8 Other specified disorders of thyroid	0.000	0.998	0.001
F22.8 Other persistent delusional disorders	0.000	0.998	0.001
G97.9 Postprocedural disorder of nervous system, unspecified	0.001	0.998	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.001	0.998	0.000
N82.8 Other female genital tract fistulae	0.001	0.998	0.000
S60.0 Contusion of finger(s) without damage to nail	0.000	0.998	0.001
E26.9 Hyperaldosteronism, unspecified	0.001	0.999	0.000
H26.8 Other specified cataract	0.000	0.999	0.001
M87.9 Osteonecrosis, unspecified	0.000	0.999	0.001
N82.5 Female genital tract-skin fistulae	0.001	0.999	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.000	0.999	0.001
C91.0 Acute lymphoblastic leukaemia	0.000	0.999	0.001
E07.1 Dyshormogenetic goitre	0.000	0.999	0.001
E07.0 Hypersecretion of calcitonin	0.000	0.999	0.001
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.999	0.001
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.999	0.001
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.001	0.999	0.000
Y57.9 Drug or medicament, unspecified	0.001	0.999	0.000
K76.8 Other specified diseases of liver	0.000	0.999	0.001
O02.8 Other specified abnormal products of conception	0.000	0.999	0.001
O62.2 Other uterine inertia	0.001	0.999	0.000
J47 Bronchiectasis	0.001	0.999	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.000	0.999	0.001
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.999	0.001
K75.3 Granulomatous hepatitis, not elsewhere classified	0.001	0.999	0.000
O66.9 Obstructed labour, unspecified	0.000	0.999	0.001
O66.4 Failed trial of labour, unspecified	0.000	0.999	0.001
O80 Single spontaneous delivery	0.001	0.999	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.999	0.001
E26.8 Other hyperaldosteronism	0.001	0.999	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.999	0.000
F22.9 Persistent delusional disorder, unspecified	0.000	0.999	0.001
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.999	0.001
D14.0 Middle ear, nasal cavity and accessory sinuses	0.001	0.999	0.000
G97.8 Other postprocedural disorders of nervous system	0.001	0.999	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.999	0.001
E00 Congenital iodine-deficiency syndrome	0.000	0.999	0.001
O66.8 Other specified obstructed labour	0.000	0.999	0.001
F30.0 Hypomania	0.001	0.999	0.000
F43.2 Adjustment disorders	0.000	0.999	0.001
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.999	0.001
O66.1 Obstructed labour due to locked twins	0.000	0.999	0.001
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.999	0.001
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.999	0.001
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.999	0.001
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.999	0.001
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.999	0.001
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.999	0.001
S60.1 Contusion of finger(s) with damage to nail	0.000	0.999	0.001
E06.9 Thyroiditis, unspecified	0.001	0.999	0.000
J32.1 Chronic frontal sinusitis	0.001	0.999	0.000
O02.9 Abnormal product of conception, unspecified	0.000	0.999	0.001
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
D86.0 Sarcoidosis of lung	0.000	0.999	0.001
I27.9 Pulmonary heart disease, unspecified	0.000	0.999	0.001
I42.2 Other hypertrophic cardiomyopathy	0.001	0.999	0.000
O80.1 Spontaneous breech delivery	0.001	0.999	0.000
J32 Chronic sinusitis	0.001	0.999	0.000
Y88 Sequelae of surgical and medical care as external cause	0.000	0.999	0.001
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.999	0.001
G82.4 Spastic tetraplegia	0.001	0.999	0.000
G82.1 Spastic paraplegia	0.001	0.999	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.999	0.001
W10.4 Street and highway	0.001	0.999	0.000
S89 Other and unspecified injuries of lower leg	0.000	0.999	0.001
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.999	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.999	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.999	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.999	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.999	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.999	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.999	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.999	0.001
K63.4 Enteroptosis	0.001	0.999	0.000
B00.1 Herpesviral vesicular dermatitis	0.001	0.999	0.000
C91.4 Hairy-cell leukaemia	0.000	0.999	0.001
E29.1 Testicular hypofunction	0.001	0.999	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.999	0.001
G45.9 Transient cerebral ischaemic attack, unspecified	0.001	0.999	0.000
O34.4 Maternal care for other abnormalities of cervix	0.000	0.999	0.001
O80.8 Other single spontaneous delivery	0.001	0.999	0.000
Z04.5 Examination and observation following other inflicted injury	0.000	0.999	0.001
C77.2 Intra-abdominal lymph nodes	0.000	0.999	0.001
F50.0 Anorexia nervosa	0.000	0.999	0.001
G82.5 Tetraplegia, unspecified	0.001	0.999	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.001	0.999	0.000
W22.9 Unspecified place	0.000	0.999	0.001
E29 Testicular dysfunction	0.001	0.999	0.000
S89.7 Multiple injuries of lower leg	0.000	0.999	0.001
S89.1 Other specified injuries of lower leg	0.000	0.999	0.001
S89.0 Multiple injuries of lower leg	0.000	0.999	0.001
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.000	0.999	0.001
K59.9 Functional intestinal disorder, unspecified	0.001	0.999	0.000
K75.4 Autoimmune hepatitis	0.001	0.999	0.000
N36.0 Urethral fistula	0.001	0.999	0.000
O64.1 Obstructed labour due to breech presentation	0.001	0.999	0.000
S60.2 Contusion of other parts of wrist and hand	0.000	0.999	0.001
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.000	0.999	0.001
I27 Other pulmonary heart diseases	0.000	0.999	0.001
R80 Isolated proteinuria	0.000	0.999	0.001
E20-E35 Disorders of other endocrine glands	0.001	0.999	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.999	0.001
C02.1 Border of tongue	0.000	0.999	0.001
C10.9 Oropharynx, unspecified	0.000	0.999	0.001
E22.1 Hyperprolactinaemia	0.001	0.999	0.000
H65.0 Acute serous otitis media	0.000	0.999	0.001
J32.3 Chronic sphenoidal sinusitis	0.001	0.999	0.000
Q83.1 Accessory breast	0.001	0.999	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.000	0.999	0.001
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.999	0.001
B01.9 Varicella without complications	0.001	0.999	0.000
C08.9 Major salivary gland, unspecified	0.000	0.999	0.001
E22.9 Hyperfunction of pituitary gland, unspecified	0.001	0.999	0.000
E29.8 Other testicular dysfunction	0.001	0.999	0.000
E29.0 Testicular hyperfunction	0.001	0.999	0.000
G80.8 Other infantile cerebral palsy	0.001	0.999	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.001	0.999	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.000	0.999	0.001
Y57.5 X-ray contrast media	0.001	0.999	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.001	0.999	0.000
F60.9 Personality disorder, unspecified	0.001	0.999	0.000
Q83.8 Other congenital malformations of breast	0.001	0.999	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.001	0.999	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.999	0.001
E20.1 Pseudohypoparathyroidism	0.001	0.999	0.000
E29.9 Testicular dysfunction, unspecified	0.001	0.999	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.999	0.001
O64.8 Obstructed labour due to other malposition and malpresentation	0.001	0.999	0.000
R45.1 Restlessness and agitation	0.001	0.999	0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.000	0.999	0.001
Z00.3 Examination for adolescent development state	0.000	0.999	0.001
Z00.2 Examination for period of rapid growth in childhood	0.000	0.999	0.001
Z00.1 Routine child health examination	0.000	0.999	0.001
Z42.1 Follow-up care involving plastic surgery of breast	0.000	0.999	0.001
E35 Disorders of endocrine glands in diseases classified elsewhere	0.001	0.999	0.000
E32 Diseases of thymus	0.001	0.999	0.000
E31 Polyglandular dysfunction	0.001	0.999	0.000
E30 Disorders of puberty, not elsewhere classified	0.001	0.999	0.000
E22 Hyperfunction of pituitary gland	0.001	0.999	0.000
E20 Hypoparathyroidism	0.001	0.999	0.000
G80 Infantile cerebral palsy	0.001	0.999	0.000
M25.84 Other specified joint disorders (Hand)	0.000	0.999	0.001
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.000	0.999	0.001
G80.0 Spastic cerebral palsy	0.001	0.999	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.001	0.999	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.999	0.001
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.001	0.999	0.000
O64.5 Obstructed labour due to compound presentation	0.001	0.999	0.000
Q25.1 Coarctation of aorta	0.000	0.999	0.001
T02.50 Fractures involving multiple regions of both lower limbs (closed)	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.999	0.001
G50.0 Trigeminal neuralgia	0.001	0.999	0.000
G80.4 Ataxic cerebral palsy	0.001	0.999	0.000
G80.3 Dyskinetic cerebral palsy	0.001	0.999	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.999	0.001
S40.8 Other superficial injuries of shoulder and upper arm	0.000	0.999	0.001
S79.9 Unspecified injury of hip and thigh	0.000	0.999	0.001
V44.5 Driver injured in traffic accident	0.000	0.999	0.001
Z04.3 Examination and observation following other accident	0.000	0.999	0.001
O64 Obstructed labour due to malposition and malpresentation of foetus	0.001	0.999	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.999	0.001
E20.8 Other hypoparathyroidism	0.001	0.999	0.000
E20.0 Idiopathic hypoparathyroidism	0.001	0.999	0.000
E22.8 Other hyperfunction of pituitary gland	0.001	0.999	0.000
E30.9 Disorder of puberty, unspecified	0.001	0.999	0.000
E30.8 Other disorders of puberty	0.001	0.999	0.000
E30.1 Precocious puberty	0.001	0.999	0.000
E30.0 Delayed puberty	0.001	0.999	0.000
E31.9 Polyglandular dysfunction, unspecified	0.001	0.999	0.000
E31.8 Other polyglandular dysfunction	0.001	0.999	0.000
E31.1 Polyglandular hyperfunction	0.001	0.999	0.000
E31.0 Autoimmune polyglandular failure	0.001	0.999	0.000
E32.9 Disease of thymus, unspecified	0.001	0.999	0.000
E32.8 Other diseases of thymus	0.001	0.999	0.000
E32.1 Abscess of thymus	0.001	0.999	0.000
E32.0 Persistent hyperplasia of thymus	0.001	0.999	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.001	0.999	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.001	0.999	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.001	0.999	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.999	0.001
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.001	0.999	0.000
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.001	0.999	0.000
O64.4 Obstructed labour due to shoulder presentation	0.001	0.999	0.000
O64.3 Obstructed labour due to brow presentation	0.001	0.999	0.000
O64.2 Obstructed labour due to face presentation	0.001	0.999	0.000
O87.2 Haemorrhoids in the puerperium	0.001	0.999	0.000
X12.0 Home	0.000	0.999	0.001
Z00.8 Other general examinations	0.000	0.999	0.001
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.000	0.999	0.001
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.999	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
E78.2 Mixed hyperlipidaemia	0.001	0.999	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.999	0.001
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.000	0.999	0.001
B24 Unspecified human immunodeficiency virus [HIV] disease	0.000	0.999	0.001
E25 Adrenogenital disorders	0.001	0.999	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.999	0.001
C02.2 Ventral surface of tongue	0.000	0.999	0.001
C71.7 Brain stem	0.000	0.999	0.001
E25.9 Adrenogenital disorder, unspecified	0.001	0.999	0.000
E25.8 Other adrenogenital disorders	0.001	0.999	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.999	0.001
R09.1 Pleurisy	0.000	0.999	0.001
R45.5 Hostility	0.001	0.999	0.000
S92.3 Fracture of metatarsal bone	0.001	0.999	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.999	0.000
Q83.3 Accessory nipple	0.001	0.999	0.000
R45.6 Physical violence	0.001	0.999	0.000
R45.2 Unhappiness	0.001	0.999	0.000
R45.0 Nervousness	0.001	0.999	0.000
S89.8 Other specified injuries of lower leg	0.000	0.999	0.001
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.000	0.999	0.001
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.001	0.999	0.000
B23.8 HIV disease resulting in other specified conditions	0.000	0.999	0.001
C06.2 Retromolar area	0.000	0.999	0.001
E20.9 Hypoparathyroidism, unspecified	0.001	0.999	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.001	0.999	0.000
G80.2 Infantile hemiplegia	0.001	0.999	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.000	0.999	0.001
T46.4 Angiotensin-converting-enzyme inhibitors	0.001	0.999	0.000
T59.8 Other specified gases, fumes and vapours	0.000	0.999	0.001
X10.0 Home	0.001	0.999	0.000
X41.9 Unspecified place	0.000	0.999	0.001
Y57.6 Other diagnostic agents	0.001	0.999	0.000
Q83 Congenital malformations of breast	0.001	0.999	0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
M43.02 Spondylolysis (Cervical region)	0.000	0.999	0.001
C04.0 Anterior floor of mouth	0.000	0.999	0.001
C08.0 Submandibular gland	0.000	0.999	0.001
G80.1 Spastic diplegia	0.001	0.999	0.000
G81.1 Spastic hemiplegia	0.001	0.999	0.000
G81.0 Flaccid hemiplegia	0.001	0.999	0.000
J01.9 Acute sinusitis, unspecified	0.000	0.999	0.001
Q83.9 Congenital malformation of breast, unspecified	0.001	0.999	0.000
Q83.2 Absent nipple	0.001	0.999	0.000
Q83.0 Congenital absence of breast with absent nipple	0.001	0.999	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.001	0.999	0.000
G81 Hemiplegia	0.001	0.999	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.000	0.999	0.001
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.000	0.999	0.001
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.000	0.999	0.001
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.000	0.999	0.001
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.000	0.999	0.001
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.000	0.999	0.001
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.000	0.999	0.001
M60.89 Other myositis (Site unspecified)	0.001	0.999	0.000
B01.8 Varicella with other complications	0.001	0.999	0.000
B01.2 Varicella pneumonia	0.001	0.999	0.000
C08.8 Overlapping lesion of major salivary glands	0.000	0.999	0.001
C08.1 Sublingual gland	0.000	0.999	0.001
D46.4 Refractory anaemia, unspecified	0.000	0.999	0.001
D89.3 Immune reconstitution syndrome	0.001	0.999	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.999	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.001	0.999	0.000
J32.4 Chronic pansinusitis	0.001	0.999	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.000	0.999	0.001
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.999	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.001	0.999	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.001	0.999	0.000
S82.70 Multiple fractures of lower leg (closed)	0.001	0.999	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.999	0.001
C02.0 Dorsal surface of tongue	0.000	0.999	0.001
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.999	0.000
G50.1 Atypical facial pain	0.001	0.999	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.999	0.001
O87.8 Other venous complications in the puerperium	0.001	0.999	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.000	0.999	0.001
V29.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
Y57.7 Vitamins, not elsewhere classified	0.001	0.999	0.000
Y57.4 Pharmaceutical excipients	0.001	0.999	0.000
Y57.3 Alcohol deterrents	0.001	0.999	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.999	0.000
Y57.1 Lipotropic drugs	0.001	0.999	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.999	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.999	0.001
Y57 Other and unspecified drugs and medicaments	0.001	0.999	0.000
M13.80 Other specified arthritis (Multiple sites)	0.001	0.999	0.000
C02.8 Overlapping lesion of tongue	0.000	0.999	0.001
C10.8 Overlapping lesion of oropharynx	0.000	0.999	0.001
C10.4 Branchial cleft	0.000	0.999	0.001
C10.3 Posterior wall of oropharynx	0.000	0.999	0.001
C10.2 Lateral wall of oropharynx	0.000	0.999	0.001
C10.1 Anterior surface of epiglottis	0.000	0.999	0.001
C10.0 Vallecula	0.000	0.999	0.001
C50.8 Overlapping lesion of breast	0.000	0.999	0.001
C71.8 Overlapping lesion of brain	0.000	0.999	0.001
C71.6 Cerebellum	0.000	0.999	0.001
C71.5 Cerebral ventricle	0.000	0.999	0.001
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.999	0.000
E28.9 Ovarian dysfunction, unspecified	0.001	0.999	0.000
E28.8 Other ovarian dysfunction	0.001	0.999	0.000
E28.1 Androgen excess	0.001	0.999	0.000
E28.0 Oestrogen excess	0.001	0.999	0.000
J92.0 Pleural plaque with presence of asbestos	0.001	0.999	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.999	0.001
Z03.9 Observation for suspected disease or condition, unspecified	0.001	0.999	0.000
C10 Malignant neoplasm of oropharynx	0.000	0.999	0.001
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.999	0.001
M65.14 Other infective (teno)synovitis (Hand)	0.001	0.999	0.000
T02.41 Fractures involving multiple regions of both upper limbs (open)	0.001	0.999	0.000
C02.4 Lingual tonsil	0.000	0.999	0.001
C50.0 Nipple and areola	0.000	0.999	0.001
C71.3 Parietal lobe	0.000	0.999	0.001
D89.1 Cryoglobulinaemia	0.001	0.999	0.000
H18.8 Other specified disorders of cornea	0.001	0.999	0.000
O86.0 Infection of obstetric surgical wound	0.000	0.999	0.001
O87.9 Venous complication in the puerperium, unspecified	0.001	0.999	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.001	0.999	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.001	0.999	0.000
S69.7 Multiple injuries of wrist and hand	0.000	0.999	0.001
Z01.5 Diagnostic skin and sensitisation tests	0.001	0.999	0.000
C71 Malignant neoplasm of brain	0.000	0.999	0.001
E28 Ovarian dysfunction	0.001	0.999	0.000
M76.69 Achilles tendinitis-Site unspec	0.000	0.999	0.001
M76.68 Achilles tendinitis-Other	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations