TreeWAS – Variant ID: rs650258

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G57.6 Lesion of plantar nerve	0.055	0.945	0.000
G57 Mononeuropathies of lower limb	0.045	0.955	0.000
G57.1 Meralgia paraesthetica	0.044	0.956	0.000
G57.5 Tarsal tunnel syndrome	0.044	0.956	0.000
G57.4 Lesion of medial popliteal nerve	0.033	0.967	0.000
G57.2 Lesion of femoral nerve	0.033	0.967	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.030	0.970	0.000
G57.0 Lesion of sciatic nerve	0.028	0.972	0.000
G25.3 Myoclonus	0.000	0.974	0.026
G25 Other extrapyramidal and movement disorders	0.000	0.974	0.026
G57.3 Lesion of lateral popliteal nerve	0.025	0.975	0.000
G57.8 Other mononeuropathies of lower limb	0.024	0.976	0.000
G24.9 Dystonia, unspecified	0.000	0.976	0.024
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.977	0.023
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.977	0.023
G24 Dystonia	0.000	0.977	0.023
G24.3 Spasmodic torticollis	0.000	0.979	0.021
G25.0 Essential tremor	0.000	0.979	0.021
R25.2 Cramp and spasm	0.000	0.979	0.021
G20-G26 Extrapyramidal and movement disorders	0.000	0.980	0.020
G25.2 Other specified forms of tremor	0.000	0.981	0.019
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.981	0.019
G25.5 Other chorea	0.000	0.981	0.019
R25 Abnormal involuntary movements	0.000	0.981	0.019
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.981	0.018
G25.4 Drug-induced chorea	0.000	0.981	0.018
G25.1 Drug-induced tremor	0.000	0.981	0.018
G24.8 Other dystonia	0.000	0.983	0.017
T43.2 Other and unspecified antidepressants	0.017	0.983	0.000
G24.4 Idiopathic orofacial dystonia	0.000	0.984	0.016
G24.2 Idiopathic nonfamilial dystonia	0.000	0.984	0.016
G24.0 Drug-induced dystonia	0.000	0.984	0.016
S60.9 Superficial injury of wrist and hand, unspecified	0.015	0.985	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.000	0.985	0.014
G22 Parkinsonism in diseases classified elsewhere	0.000	0.985	0.014
G24.5 Blepharospasm	0.000	0.985	0.014
G24.1 Idiopathic familial dystonia	0.000	0.986	0.014
Z35.0 Supervision of pregnancy with history of infertility	0.014	0.986	0.000
R25.0 Abnormal head movements	0.000	0.986	0.014
G21 Secondary Parkinsonism	0.000	0.986	0.013
R25.1 Tremor, unspecified	0.000	0.987	0.013
A04.7 Enterocolitis due to Clostridium difficile	0.012	0.988	0.000
G23 Other degenerative diseases of basal ganglia	0.000	0.988	0.012
G21.1 Other drug-induced secondary Parkinsonism	0.000	0.989	0.011
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.989	0.011
E24.9 Cushing's syndrome, unspecified	0.010	0.990	0.000
F52.2 Failure of genital response	0.000	0.990	0.010
G21.8 Other secondary Parkinsonism	0.000	0.990	0.010
G21.3 Postencephalitic Parkinsonism	0.000	0.990	0.010
G21.2 Secondary Parkinsonism due to other external agents	0.000	0.990	0.010
N42.8 Other specified disorders of prostate	0.000	0.990	0.010
G21.9 Secondary Parkinsonism, unspecified	0.000	0.990	0.009
G21.4 Vascular parkinsonism	0.000	0.991	0.009
G20 Parkinson's disease	0.000	0.991	0.009
G21.0 Malignant neuroleptic syndrome	0.000	0.991	0.009
Y86 Sequelae of other accidents	0.009	0.991	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.000	0.991	0.008
G23.3 Multiple system atrophy, cerebellar type	0.000	0.991	0.008
G23.2 Striatonigral degeneration	0.000	0.991	0.008
G23.0 Hallervorden-Spatz disease	0.000	0.991	0.008
R54 Senility	0.000	0.992	0.008
E24 Cushing's syndrome	0.008	0.992	0.000
M48.06 Spinal stenosis (Lumbar region)	0.000	0.992	0.008
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.000	0.992	0.008
K57.1 Diverticular disease of small intestine without perforation or abscess	0.008	0.992	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.992	0.008
M48.0 Spinal stenosis	0.000	0.993	0.007
G23.8 Other specified degenerative diseases of basal ganglia	0.000	0.993	0.007
E24.0 Pituitary-dependent Cushing's disease	0.007	0.993	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.007	0.993	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.007	0.993	0.000
R25.3 Fasciculation	0.000	0.993	0.006
E24.8 Other Cushing's syndrome	0.007	0.993	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.006	0.994	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.006	0.994	0.000
Y85 Sequelae of transport accidents	0.006	0.994	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
Z35 Supervision of high-risk pregnancy	0.006	0.994	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.006	0.994	0.000
E24.3 Ectopic ACTH syndrome	0.006	0.994	0.000
E24.1 Nelson's syndrome	0.006	0.994	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.994	0.006
E27.8 Other specified disorders of adrenal gland	0.006	0.994	0.000
Y89 Sequelae of other external causes	0.006	0.994	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.006	0.994	0.000
Y87.1 Sequelae of assault	0.006	0.994	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.006	0.994	0.000
E27.2 Addisonian crisis	0.006	0.994	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.006	0.994	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.006	0.994	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.006	0.994	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.994	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.006	0.994	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.994	0.006
T43.6 Psychostimulants with abuse potential	0.005	0.994	0.000
E20-E35 Disorders of other endocrine glands	0.006	0.994	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.995	0.005
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.995	0.005
E27.1 Primary adrenocortical insufficiency	0.005	0.995	0.000
E24.2 Drug-induced Cushing's syndrome	0.005	0.995	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.995	0.005
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.005	0.995	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.005	0.995	0.000
T50.1 Loop [high-ceiling] diuretics	0.005	0.995	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
Y89.9 Sequelae of unspecified external cause	0.005	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.005	0.995	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.995	0.005
W02.9 Unspecified place	0.000	0.995	0.005
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.005	0.995	0.000
Y87.2 Sequelae of events of undetermined intent	0.005	0.995	0.000
T50.8 Diagnostic agents	0.005	0.995	0.000
T50.4 Drugs affecting uric acid metabolism	0.005	0.995	0.000
H81.0 Meniere's disease	0.005	0.995	0.000
E27.9 Disorder of adrenal gland, unspecified	0.005	0.995	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.995	0.005
E27.5 Adrenomedullary hyperfunction	0.005	0.995	0.000
E27.0 Other adrenocortical overactivity	0.005	0.995	0.000
Y85.0 Sequelae of motor-vehicle accident	0.005	0.995	0.000
T50.7 Analeptics and opioid receptor antagonists	0.005	0.995	0.000
T50.5 Appetite depressants	0.005	0.995	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.005	0.995	0.000
T50.0 Mineralocorticoids and their antagonists	0.005	0.995	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
Y87.0 Sequelae of intentional self-harm	0.005	0.995	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.005	0.995	0.000
Z35.6 Supervision of very young primigravida	0.005	0.995	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.005	0.995	0.000
O00.1 Tubal pregnancy	0.000	0.995	0.005
E20 Hypoparathyroidism	0.005	0.995	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.005	0.995	0.000
Y45.1 Salicylates	0.000	0.995	0.005
E31 Polyglandular dysfunction	0.004	0.995	0.000
E23 Hypofunction and other disorders of pituitary gland	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.004	0.995	0.000
Y89.1 Sequelae of war operations	0.004	0.995	0.000
Y89.0 Sequelae of legal intervention	0.004	0.995	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.995	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.004	0.996	0.000
E32 Diseases of thymus	0.004	0.996	0.000
Y88 Sequelae of surgical and medical care as external cause	0.004	0.996	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.996	0.004
S27.2 Traumatic heamopneumothorax	0.004	0.996	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E30 Disorders of puberty, not elsewhere classified	0.004	0.996	0.000
E22 Hyperfunction of pituitary gland	0.004	0.996	0.000
R01.0 Benign and innocent cardiac murmurs	0.000	0.996	0.004
E34 Other endocrine disorders	0.004	0.996	0.000
E23.6 Other disorders of pituitary gland	0.004	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
G35 Multiple sclerosis	0.004	0.996	0.000
E20.8 Other hypoparathyroidism	0.004	0.996	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.004	0.996	0.000
E29 Testicular dysfunction	0.004	0.996	0.000
E25 Adrenogenital disorders	0.004	0.996	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.996	0.004
M48 Other spondylopathies	0.000	0.996	0.004
H54.7 Unspecified visual loss	0.000	0.996	0.004
E31.0 Autoimmune polyglandular failure	0.004	0.996	0.000
S32.0 Fracture of lumbar vertebra	0.004	0.996	0.000
E23.0 Hypopituitarism	0.004	0.996	0.000
T42.3 Barbiturates	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
I35.1 Aortic (valve) insufficiency	0.004	0.996	0.000
Y45.0 Opioids and related analgesics	0.000	0.996	0.004
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.996	0.004
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
Z35.8 Supervision of other high-risk pregnancies	0.004	0.996	0.000
Z35.5 Supervision of elderly primigravida	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
M48.04 Spinal stenosis (Thoracic region)	0.000	0.996	0.003
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
E20.9 Hypoparathyroidism, unspecified	0.004	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.004	0.996	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.004	0.996	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.996	0.000
E20.0 Idiopathic hypoparathyroidism	0.003	0.996	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.996	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.004	0.996	0.000
M47.1 Other spondylosis with myelopathy	0.000	0.996	0.004
E26 Hyperaldosteronism	0.003	0.996	0.000
E14.9 Without complications	0.004	0.996	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.996	0.000
E31.8 Other polyglandular dysfunction	0.003	0.996	0.000
E31.1 Polyglandular hyperfunction	0.003	0.996	0.000
E34.8 Other specified endocrine disorders	0.003	0.996	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.996	0.000
E32.9 Disease of thymus, unspecified	0.003	0.996	0.000
M47.9 Spondylosis, unspecified	0.000	0.996	0.004
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.996	0.004
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.996	0.004
H65.9 Nonsuppurative otitis media, unspecified	0.004	0.996	0.000
E22.1 Hyperprolactinaemia	0.003	0.996	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.000	0.997	0.003
E28 Ovarian dysfunction	0.003	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
Y45.5 4-Aminophenol derivatives	0.000	0.997	0.003
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
E32.8 Other diseases of thymus	0.003	0.997	0.000
E32.1 Abscess of thymus	0.003	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.997	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.997	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.997	0.003
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.003	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.003	0.997	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.997	0.003
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.997	0.003
F52.7 Excessive sexual drive	0.000	0.997	0.003
F52.6 Nonorganic dyspareunia	0.000	0.997	0.003
F52.5 Nonorganic vaginismus	0.000	0.997	0.003
F52.4 Premature ejaculation	0.000	0.997	0.003
F52.3 Orgasmic dysfunction	0.000	0.997	0.003
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.997	0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.997	0.003
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.003	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.997	0.000
E30.8 Other disorders of puberty	0.003	0.997	0.000
E30.1 Precocious puberty	0.003	0.997	0.000
E30.0 Delayed puberty	0.003	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.997	0.000
E34.3 Short stature, not elsewhere classified	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.997	0.003
M47 Spondylosis	0.000	0.997	0.003
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.997	0.003
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.003	0.997	0.000
D35.2 Pituitary gland	0.003	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.003	0.997	0.000
E25.8 Other adrenogenital disorders	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.003	0.997	0.000
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
T42.4 Benzodiazepines	0.003	0.997	0.000
M48.4 Fatigue fracture of vertebra	0.000	0.997	0.003
M48.3 Traumatic spondylopathy	0.000	0.997	0.003
M48.2 Kissing spine	0.000	0.997	0.003
M48.1 Ankylosing hyperostosis [Forestier]	0.000	0.997	0.003
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.003	0.997	0.000
S32.01 Fracture of lumbar vertebra (open)	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.997	0.003
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.000	0.997	0.003
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T36.4 Tetracyclines	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
S27 Injury of other and unspecified intrathoracic organs	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T36.3 Macrolides	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
T45.4 Iron and its compounds	0.003	0.997	0.000
T47.2 Stimulant laxatives	0.003	0.997	0.000
M48.8 Other specified spondylopathies	0.000	0.997	0.003
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.003	0.997	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.000	0.997	0.003
T36.0 Penicillins	0.003	0.997	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
T46.7 Peripheral vasodilators	0.003	0.997	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
D61.9 Aplastic anaemia, unspecified	0.003	0.997	0.000
F52.0 Lack or loss of sexual desire	0.000	0.997	0.003
Y45.2 Propionic acid derivatives	0.000	0.997	0.003
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.4 Other laxatives	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.000	0.997	0.003
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.000	0.997	0.003
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.000	0.997	0.003
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.000	0.997	0.003
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.000	0.997	0.003
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.000	0.997	0.003
E26.8 Other hyperaldosteronism	0.003	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
C45.9 Mesothelioma, unspecified	0.003	0.997	0.000
E23.2 Diabetes insipidus	0.003	0.997	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.003	0.997	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.000	0.997	0.003
M48.9 Spondylopathy, unspecified	0.000	0.997	0.003
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.997	0.003
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.003	0.997	0.000
E28.8 Other ovarian dysfunction	0.003	0.997	0.000
E28.1 Androgen excess	0.003	0.997	0.000
E28.0 Oestrogen excess	0.003	0.997	0.000
H65.2 Chronic serous otitis media	0.003	0.997	0.000
A04 Other bacterial intestinal infections	0.003	0.997	0.000
C81.1 Nodular sclerosis	0.000	0.997	0.003
S27.8 Injury of other specified intrathoracic organs	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.997	0.000
T45.2 Vitamins, not elsewhere classified	0.003	0.997	0.000
M47.8 Other spondylosis	0.000	0.997	0.003
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
S27.0 Traumatic pneumothorax	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.997	0.003
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.997	0.003
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.997	0.003
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.997	0.003
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.997	0.003
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.997	0.000
E28.3 Primary ovarian failure	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.002	0.997	0.000
T49.8 Other topical agents	0.002	0.997	0.000
T49.7 Dental drugs, topically applied	0.002	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.997	0.000
T49.2 Local astringents and local detergents	0.002	0.997	0.000
T49.1 Antipruritics	0.002	0.997	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.997	0.003
Y84.6 Urinary catheterisation	0.003	0.997	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.997	0.002
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.003	0.997	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.000	0.997	0.002
S27.3 Other injuries of lung	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.997	0.000
T48.4 Expectorants	0.002	0.997	0.000
T48.3 Antitussives	0.002	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.997	0.000
T48.0 Oxytocic drugs	0.002	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.003	0.997	0.000
A04.9 Bacterial intestinal infection, unspecified	0.003	0.997	0.000
E34.0 Carcinoid syndrome	0.002	0.997	0.000
I87.8 Other specified disorders of veins	0.003	0.997	0.000
Y45.4 Antirheumatics	0.000	0.997	0.002
H65.0 Acute serous otitis media	0.003	0.997	0.000
Y45.8 Other analgesics and antipyretics	0.000	0.997	0.002
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.000	0.997	0.002
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.000	0.997	0.002
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.000	0.997	0.002
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.000	0.997	0.002
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.000	0.997	0.002
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.000	0.997	0.002
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.000	0.997	0.002
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.000	0.997	0.002
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.000	0.997	0.002
M48.29 Kissing spine (Site unspecified)	0.000	0.997	0.002
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M48.27 Kissing spine (Lumbosacral region)	0.000	0.997	0.002
M48.26 Kissing spine (Lumbar region)	0.000	0.997	0.002
M48.25 Kissing spine (Thoracolumbar region)	0.000	0.997	0.002
M48.24 Kissing spine (Thoracic region)	0.000	0.997	0.002
M48.23 Kissing spine (Cervicothoracic region)	0.000	0.997	0.002
M48.22 Kissing spine (Cervical region)	0.000	0.997	0.002
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.000	0.997	0.002
M48.20 Kissing spine (Multiple sites in spine)	0.000	0.997	0.002
M48.39 Traumatic spondylopathy (Site unspecified)	0.000	0.997	0.002
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.000	0.997	0.002
M48.36 Traumatic spondylopathy (Lumbar region)	0.000	0.997	0.002
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.000	0.997	0.002
M48.34 Traumatic spondylopathy (Thoracic region)	0.000	0.997	0.002
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.000	0.997	0.002
M48.32 Traumatic spondylopathy (Cervical region)	0.000	0.997	0.002
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.000	0.997	0.002
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.000	0.997	0.002
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.000	0.997	0.002
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.000	0.997	0.002
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.000	0.997	0.002
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.000	0.997	0.002
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.000	0.997	0.002
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.000	0.997	0.002
M48.42 Fatigue fracture of vertebra (Cervical region)	0.000	0.997	0.002
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.000	0.997	0.002
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.000	0.997	0.002
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
A04.4 Other intestinal Escherichia coli infections	0.002	0.998	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.002	0.998	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
S27.9 Injury of unspecified intrathoracic organ	0.002	0.998	0.000
S27.7 Multiple injuries of intrathoracic organs	0.002	0.998	0.000
S27.6 Injury of pleura	0.002	0.998	0.000
S27.5 Injury of thoracic trachea	0.002	0.998	0.000
S27.4 Injury of bronchus	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.000	0.998	0.002
M48.84 Other specified spondylopathies (Thoracic region)	0.000	0.998	0.002
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.000	0.998	0.002
M48.82 Other specified spondylopathies (Cervical region)	0.000	0.998	0.002
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.000	0.998	0.002
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
W29.9 Unspecified place	0.002	0.998	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.002
S32.3 Fracture of ilium	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.998	0.002
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.998	0.002
S32.30 Fracture of ilium (closed)	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.002	0.998	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.000	0.998	0.002
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M48.94 Spondylopathy, unspecified (Thoracic region)	0.000	0.998	0.002
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.002
S60 Superficial injury of wrist and hand	0.002	0.998	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.000	0.998	0.002
S27.1 Traumatic haemothorax	0.002	0.998	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.002	0.998	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.002	0.998	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.002	0.998	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.002	0.998	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.002	0.998	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.002	0.998	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.998	0.002
Q12.0 Congenital cataract	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.000	0.998	0.002
M48.86 Other specified spondylopathies (Lumbar region)	0.000	0.998	0.002
M48.92 Spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
T51.0 Ethanol	0.002	0.998	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.998	0.002
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
E14 Unspecified diabetes mellitus	0.002	0.998	0.000
M47.84 Other spondylosis (Thoracic region)	0.000	0.998	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.000	0.998	0.002
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations