TreeWAS – Variant ID: rs6510489

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K86.3 Pseudocyst of pancreas	0.029	0.971	0.000
K86 Other diseases of pancreas	0.028	0.972	0.000
K86.8 Other specified diseases of pancreas	0.026	0.974	0.000
K86.2 Cyst of pancreas	0.025	0.975	0.000
K86.9 Disease of pancreas, unspecified	0.024	0.976	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.023	0.977	0.000
S72.40 Fracture of lower end of femur (closed)	0.022	0.978	0.000
K86.1 Other chronic pancreatitis	0.022	0.978	0.000
S72.4 Fracture of lower end of femur	0.020	0.980	0.000
S72.41 Fracture of lower end of femur (open)	0.018	0.982	0.000
S72 Fracture of femur	0.018	0.982	0.000
S72.20 Subtrochanteric fracture (closed)	0.018	0.982	0.000
S72.2 Subtrochanteric fracture	0.017	0.983	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.985	0.015
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.985	0.015
S72.3 Fracture of shaft of femur	0.014	0.986	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.987	0.013
S72.8 Fractures of other parts of femur	0.013	0.987	0.000
S72.7 Multiple fractures of femur	0.013	0.987	0.000
S72.21 Subtrochanteric fracture (open)	0.013	0.987	0.000
S70-S79 Injuries to the hip and thigh	0.013	0.987	0.000
S72.1 Pertrochanteric fracture	0.012	0.988	0.000
S70 Superficial injury of hip and thigh	0.012	0.988	0.000
S72.9 Fracture of femur, part unspecified	0.012	0.988	0.000
S72.30 Fracture of shaft of femur (closed)	0.012	0.988	0.000
M20.2 Hallux rigidus	0.000	0.988	0.012
S70.0 Contusion of hip	0.011	0.989	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.989	0.011
S70.1 Contusion of thigh	0.011	0.989	0.000
M20 Acquired deformities of fingers and toes	0.000	0.989	0.011
S72.31 Fracture of shaft of femur (open)	0.011	0.989	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.010	0.990	0.000
M20.0 Deformity of finger(s)	0.000	0.990	0.010
S72.80 Fractures of other parts of femur (closed)	0.010	0.990	0.000
S72.81 Fractures of other parts of femur (open)	0.009	0.990	0.000
S72.71 Multiple fractures of femur (open)	0.009	0.990	0.000
S72.70 Multiple fractures of femur (closed)	0.009	0.990	0.000
S79 Other and unspecified injuries of hip and thigh	0.010	0.990	0.000
S71 Open wound of hip and thigh	0.009	0.990	0.000
S78 Traumatic amputation of hip and thigh	0.009	0.991	0.000
S77 Crushing injury of hip and thigh	0.009	0.991	0.000
S75 Injury of blood vessels at hip and thigh level	0.009	0.991	0.000
S74 Injury of nerves at hip and thigh level	0.009	0.991	0.000
G20 Parkinson's disease	0.009	0.991	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.009	0.991	0.000
S72.11 Pertrochanteric fracture (open)	0.009	0.991	0.000
S72.91 Fracture of femur, part unspecified (open)	0.009	0.991	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.009	0.991	0.000
S72.0 Fracture of neck of femur	0.009	0.991	0.000
F41.1 Generalised anxiety disorder	0.008	0.992	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.008	0.992	0.000
S72.10 Pertrochanteric fracture (closed)	0.008	0.992	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.007	0.992	0.000
S70.8 Other superficial injuries of hip and thigh	0.008	0.992	0.000
S79.9 Unspecified injury of hip and thigh	0.008	0.992	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.992	0.008
S76.1 Injury of quadriceps muscle and tendon	0.007	0.993	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.007	0.993	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.007	0.993	0.000
S76.0 Injury of muscle and tendon of hip	0.007	0.993	0.000
N13 Obstructive and reflux uropathy	0.000	0.993	0.007
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.007	0.993	0.000
N13.6 Pyonephrosis	0.000	0.993	0.007
S73.1 Sprain and strain of hip	0.007	0.993	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.993	0.007
S71.1 Open wound of thigh	0.007	0.993	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.993	0.007
S79.7 Multiple injuries of hip and thigh	0.007	0.993	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.007	0.993	0.000
S71.7 Multiple open wounds of of hip and thigh	0.007	0.993	0.000
S71.0 Open wound of hip	0.007	0.993	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.007	0.993	0.000
S74.8 Injury of other nerves at hip and thigh level	0.007	0.993	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.007	0.993	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.007	0.993	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.007	0.993	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.007	0.993	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.007	0.993	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.007	0.993	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.007	0.993	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.007	0.993	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.007	0.993	0.000
S75.0 Injury of femoral artery	0.007	0.993	0.000
S77.2 Crushing injury of hip with thigh	0.007	0.993	0.000
S77.1 Crushing injury of thigh	0.007	0.993	0.000
S77.0 Crushing injury of hip	0.007	0.993	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.007	0.993	0.000
S78.1 Traumatic amputation at level between hip and knee	0.007	0.993	0.000
S78.0 Traumatic amputation at hip joint	0.007	0.993	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.007	0.993	0.000
S79.8 Other specified injuries of hip and thigh	0.007	0.993	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.993	0.007
N10-N16 Renal tubulo-interstitial diseases	0.000	0.993	0.007
S72.01 Fracture of neck of femur (open)	0.006	0.993	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.994	0.006
N50.1 Vascular disorders of male genital organs	0.006	0.994	0.000
M45 Ankylosing spondylitis	0.000	0.994	0.006
T45.0 Antiallergic and antiemetic drugs	0.006	0.994	0.000
T45.5 Anticoagulants	0.006	0.994	0.000
N10 Acute tubulo-interstitial nephritis	0.000	0.994	0.006
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.006	0.994	0.000
F31 Bipolar affective disorder	0.000	0.994	0.006
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.005	0.994	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.994	0.006
S73.0 Dislocation of hip	0.005	0.995	0.000
I49.9 Cardiac arrhythmia, unspecified	0.005	0.995	0.000
N11 Chronic tubulo-interstitial nephritis	0.000	0.995	0.005
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.995	0.005
M20.5 Other deformities of toe(s) (acquired)	0.000	0.995	0.005
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.995	0.005
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.995	0.005
T45.2 Vitamins, not elsewhere classified	0.005	0.995	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.995	0.005
I08.0 Disorders of both mitral and aortic valves	0.000	0.995	0.005
T45.1 Antineoplastic and immunosuppressive drugs	0.005	0.995	0.000
N15 Other renal tubulo-interstitial diseases	0.000	0.995	0.005
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.995	0.005
I08 Multiple valve diseases	0.000	0.995	0.005
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.995	0.005
N13.4 Hydroureter	0.000	0.995	0.005
F31.7 Bipolar affective disorder, currently in remission	0.000	0.995	0.005
G50.0 Trigeminal neuralgia	0.005	0.995	0.000
I49.8 Other specified cardiac arrhythmias	0.005	0.995	0.000
F31.8 Other bipolar affective disorders	0.000	0.995	0.004
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.996	0.004
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.996	0.004
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.996	0.004
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.996	0.004
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.996	0.004
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.996	0.004
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.996	0.004
N11.1 Chronic obstructive pyelonephritis	0.000	0.996	0.004
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.996	0.004
T45.9 Primarily systemic and haematological agent, unspecified	0.004	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.004	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.004	0.996	0.000
T45.4 Iron and its compounds	0.004	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.004	0.996	0.000
I05.0 Mitral stenosis	0.000	0.996	0.004
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.996	0.004
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.996	0.004
H17.9 Corneal scar and opacity, unspecified	0.000	0.996	0.004
M79.79 Fibromyalgia (Site unspecified)	0.004	0.996	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.000	0.996	0.004
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.996	0.004
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.996	0.004
T92.2 Sequelae of fracture at wrist and hand level	0.004	0.996	0.000
T40.2 Other opioids	0.004	0.996	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.996	0.004
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.000	0.996	0.004
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.996	0.004
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.996	0.004
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.996	0.004
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.996	0.004
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
S42.00 Fracture of clavicle (closed)	0.000	0.996	0.004
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.996	0.004
N14.3 Nephropathy induced by heavy metals	0.000	0.996	0.004
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.996	0.004
N14.0 Analgesic nephropathy	0.000	0.996	0.004
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.996	0.004
N15.0 Balkan nephropathy	0.000	0.996	0.004
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.996	0.004
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.996	0.003
F19.1 Harmful use	0.004	0.996	0.000
N15.1 Renal and perinephric abscess	0.000	0.996	0.003
I08.9 Multiple valve disease, unspecified	0.000	0.996	0.003
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.996	0.003
I05 Rheumatic mitral valve diseases	0.000	0.996	0.004
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.997	0.003
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.997	0.003
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.997	0.003
G20-G26 Extrapyramidal and movement disorders	0.003	0.997	0.000
F52.2 Failure of genital response	0.003	0.997	0.000
S02.00 Fracture of vault of skull (closed)	0.003	0.997	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.997	0.003
H17 Corneal scars and opacities	0.000	0.997	0.003
H20 Iridocyclitis	0.000	0.997	0.003
N13.3 Other and unspecified hydronephrosis	0.000	0.997	0.003
I05-I09 Chronic rheumatic heart diseases	0.000	0.997	0.003
N13.8 Other obstructive and reflux uropathy	0.000	0.997	0.003
H17.8 Other corneal scars and opacities	0.000	0.997	0.003
I05.2 Mitral stenosis with insufficiency	0.000	0.997	0.003
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.997	0.003
T92 Sequelae of injuries of upper limb	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.000	0.997	0.003
I05.9 Mitral valve disease, unspecified	0.000	0.997	0.003
T93.0 Sequelae of open wound of lower limb	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.003	0.997	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.997	0.002
G23 Other degenerative diseases of basal ganglia	0.003	0.997	0.000
G25.3 Myoclonus	0.003	0.997	0.000
G21 Secondary Parkinsonism	0.003	0.997	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.003	0.997	0.000
G22 Parkinsonism in diseases classified elsewhere	0.003	0.997	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.997	0.003
T92.8 Sequelae of other specified injuries of upper limb	0.003	0.997	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.003	0.997	0.000
W44.0 Home	0.000	0.997	0.003
S92.00 Fracture of calcaneus (closed)	0.000	0.997	0.003
G25 Other extrapyramidal and movement disorders	0.003	0.997	0.000
I06 Rheumatic aortic valve diseases	0.000	0.997	0.003
H17.1 Other central corneal opacity	0.000	0.997	0.002
H17.0 Adherent leukoma	0.000	0.997	0.002
T92.9 Sequelae of unspecified injury of upper limb	0.003	0.997	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.002	0.997	0.000
H20.2 Lens-induced iridocyclitis	0.000	0.997	0.002
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.997	0.002
Z34.0 Supervision of normal first pregnancy	0.000	0.997	0.003
H20.8 Other iridocyclitis	0.000	0.997	0.002
G50 Disorders of trigeminal nerve	0.002	0.997	0.000
F19.2 Dependence syndrome	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.998	0.002
M79.7 Fibromyalgia	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
T93 Sequelae of injuries of lower limb	0.002	0.998	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
C69.3 Choroid	0.000	0.998	0.002
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.002	0.998	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
G24 Dystonia	0.002	0.998	0.000
G71.1 Myotonic disorders	0.002	0.998	0.000
H20.1 Chronic iridocyclitis	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
G50.1 Atypical facial pain	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.000	0.998	0.002
M79.70 Fibromyalgia (Multiple sites)	0.002	0.998	0.000
T92.0 Sequelae of open wound of upper limb	0.002	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.000	0.998	0.002
I09 Other rheumatic heart diseases	0.000	0.998	0.002
F19.9 Unspecified mental and behavioural disorder	0.002	0.998	0.000
F19.8 Other mental and behavioural disorders	0.002	0.998	0.000
F19.7 Residual and late-onset psychotic disorder	0.002	0.998	0.000
F19.6 Amnesic syndrome	0.002	0.998	0.000
F19.5 Psychotic disorder	0.002	0.998	0.000
F19.4 Withdrawal state with delirium	0.002	0.998	0.000
F19.3 Withdrawal state	0.002	0.998	0.000
F19.0 Acute intoxication	0.002	0.998	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.002	0.998	0.000
G21.9 Secondary Parkinsonism, unspecified	0.002	0.998	0.000
G21.8 Other secondary Parkinsonism	0.002	0.998	0.000
G21.4 Vascular parkinsonism	0.002	0.998	0.000
G21.3 Postencephalitic Parkinsonism	0.002	0.998	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.002	0.998	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.002	0.998	0.000
G21.0 Malignant neuroleptic syndrome	0.002	0.998	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.002	0.998	0.000
G23.3 Multiple system atrophy, cerebellar type	0.002	0.998	0.000
G23.2 Striatonigral degeneration	0.002	0.998	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.002	0.998	0.000
G23.0 Hallervorden-Spatz disease	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.002	0.998	0.000
I08.8 Other multiple valve diseases	0.000	0.998	0.002
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.002	0.998	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.998	0.002
T88.4 Failed or difficult intubation	0.002	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.002	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.002	0.998	0.000
G25.5 Other chorea	0.002	0.998	0.000
G25.4 Drug-induced chorea	0.002	0.998	0.000
G25.1 Drug-induced tremor	0.002	0.998	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.998	0.002
I06.8 Other rheumatic aortic valve diseases	0.000	0.998	0.002
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.998	0.002
I06.1 Rheumatic aortic insufficiency	0.000	0.998	0.002
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.998	0.002
T92.1 Sequelae of fracture of arm	0.002	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.002	0.998	0.000
F01.9 Vascular dementia, unspecified	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
F11.3 Withdrawal state	0.002	0.998	0.000
G50.9 Disorder of trigeminal nerve, unspecified	0.002	0.998	0.000
G50.8 Other disorders of trigeminal nerve	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
M79.78 Fibromyalgia (Other)	0.002	0.998	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.002	0.998	0.000
M79.76 Fibromyalgia (Lower leg)	0.002	0.998	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.002	0.998	0.000
M79.74 Fibromyalgia (Hand)	0.002	0.998	0.000
M79.73 Fibromyalgia (Forearm)	0.002	0.998	0.000
M79.72 Fibromyalgia (Upper arm)	0.002	0.998	0.000
M79.71 Fibromyalgia (Shoulder region)	0.002	0.998	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.998	0.002
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
N48.4 Impotence of organic origin	0.000	0.998	0.002
S42.0 Fracture of clavicle	0.000	0.998	0.002
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.998	0.002
T88 Other complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
G24.4 Idiopathic orofacial dystonia	0.002	0.998	0.000
G24.2 Idiopathic nonfamilial dystonia	0.002	0.998	0.000
G24.1 Idiopathic familial dystonia	0.002	0.998	0.000
G24.0 Drug-induced dystonia	0.002	0.998	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.002	0.998	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.998	0.002
G25.0 Essential tremor	0.002	0.998	0.000
S02.0 Fracture of vault of skull	0.002	0.998	0.000
S83.1 Dislocation of knee	0.002	0.998	0.000
I49 Other cardiac arrhythmias	0.002	0.998	0.000
I09.8 Other specified rheumatic heart diseases	0.000	0.998	0.002
I09.2 Chronic rheumatic pericarditis	0.000	0.998	0.002
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.998	0.002
I09.0 Rheumatic myocarditis	0.000	0.998	0.002
J04.0 Acute laryngitis	0.000	0.998	0.002
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.002	0.998	0.000
R09.1 Pleurisy	0.002	0.998	0.000
Z71.9 Counselling, unspecified	0.002	0.998	0.000
F11 Mental and behavioural disorders due to use of opioids	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.002	0.998	0.000
L95.9 Vasculitis limited to skin, unspecified	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
F11.1 Harmful use	0.002	0.998	0.000
G25.2 Other specified forms of tremor	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
J30.1 Allergic rhinitis due to pollen	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
F25 Schizoaffective disorders	0.002	0.998	0.000
F12.2 Dependence syndrome	0.002	0.998	0.000
G24.3 Spasmodic torticollis	0.002	0.998	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
G24.8 Other dystonia	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.998	0.002
F12 Mental and behavioural disorders due to use of cannabinoids	0.002	0.998	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.998	0.002
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.7 Excessive sexual drive	0.002	0.998	0.000
F52.6 Nonorganic dyspareunia	0.002	0.998	0.000
F52.5 Nonorganic vaginismus	0.002	0.998	0.000
F52.4 Premature ejaculation	0.002	0.998	0.000
F52.3 Orgasmic dysfunction	0.002	0.998	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.002	0.998	0.000
F52.0 Lack or loss of sexual desire	0.002	0.998	0.000
Z34 Supervision of normal pregnancy	0.000	0.998	0.002
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.998	0.002
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.002	0.998	0.000
S42.01 Fracture of clavicle (open)	0.000	0.998	0.001
K00.6 Disturbances in tooth eruption	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.002	0.998	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M25.51 Pain in joint (Shoulder region)	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.002	0.998	0.000
T88.2 Shock due to anaesthesia	0.002	0.998	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.002	0.998	0.000
T88.0 Infection following immunisation	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
F22.0 Delusional disorder	0.002	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.998	0.001
I07.8 Other tricuspid valve diseases	0.000	0.998	0.001
I07.2 Tricuspid stenosis with insufficiency	0.000	0.998	0.001
I07.0 Tricuspid stenosis	0.000	0.998	0.001
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
T88.9 Complication of surgical and medical care, unspecified	0.002	0.998	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.001	0.998	0.000
S02.11 Fracture of base of skull (open)	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
I09.9 Rheumatic heart disease, unspecified	0.000	0.998	0.001
I49.2 Junctional premature depolarisation	0.002	0.998	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.002	0.998	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.002	0.998	0.000
S83.0 Dislocation of patella	0.001	0.998	0.000
N23 Unspecified renal colic	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
F14.1 Harmful use	0.001	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
T48.5 Anti-common-cold drugs	0.001	0.998	0.000
T48.4 Expectorants	0.001	0.998	0.000
T48.3 Antitussives	0.001	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
T48.0 Oxytocic drugs	0.001	0.998	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.001	0.998	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.000	0.998	0.002
F11.9 Unspecified mental and behavioural disorder	0.001	0.998	0.000
F11.8 Other mental and behavioural disorders	0.001	0.998	0.000
F11.7 Residual and late-onset psychotic disorder	0.001	0.998	0.000
F11.6 Amnesic syndrome	0.001	0.998	0.000
F11.5 Psychotic disorder	0.001	0.998	0.000
F11.4 Withdrawal state with delirium	0.001	0.998	0.000
F11.0 Acute intoxication	0.001	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.001	0.998	0.000
F25.8 Other schizoaffective disorders	0.001	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.001	0.998	0.000
G24.5 Blepharospasm	0.001	0.998	0.000
S83.7 Injury to multiple structures of knee	0.001	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
F12.9 Unspecified mental and behavioural disorder	0.001	0.998	0.000
F12.8 Other mental and behavioural disorders	0.001	0.998	0.000
F12.7 Residual and late-onset psychotic disorder	0.001	0.998	0.000
F12.6 Amnesic syndrome	0.001	0.998	0.000
F12.5 Psychotic disorder	0.001	0.998	0.000
F12.4 Withdrawal state with delirium	0.001	0.998	0.000
F12.3 Withdrawal state	0.001	0.998	0.000
F12.1 Harmful use	0.001	0.998	0.000
F12.0 Acute intoxication	0.001	0.998	0.000
M00.9 Pyogenic arthritis, unspecified	0.002	0.998	0.000
X62.9 Unspecified place	0.002	0.998	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.998	0.002
F18 Mental and behavioural disorders due to use of volatile solvents	0.001	0.998	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.001	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.001
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.000	0.998	0.001
D68.5 Primary Thrombophilia	0.001	0.998	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.000	0.998	0.001
Q66.9 Congenital deformity of feet, unspecified	0.001	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.998	0.000
Q66.5 Congenital pes planus	0.001	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.000
Q66.1 Talipes calcaneovarus	0.001	0.998	0.000
Q66.0 Talipes equinovarus	0.001	0.998	0.000
T41.5 Therapeutic gases	0.001	0.998	0.000
T41.4 Anaesthetic, unspecified	0.001	0.998	0.000
T41.3 Local anaesthetics	0.001	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
T41.1 Intravenous anaesthetics	0.001	0.998	0.000
T41.0 Inhaled anaesthetics	0.001	0.998	0.000
T49.9 Topical agent, unspecified	0.001	0.998	0.000
T49.8 Other topical agents	0.001	0.998	0.000
T49.7 Dental drugs, topically applied	0.001	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.998	0.000
T49.2 Local astringents and local detergents	0.001	0.998	0.000
T49.1 Antipruritics	0.001	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.998	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.001	0.998	0.000
C45.0 Mesothelioma of pleura	0.000	0.999	0.001
M75.2 Bicipital tendinitis	0.000	0.999	0.001
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.001	0.999	0.000
F14.9 Unspecified mental and behavioural disorder	0.001	0.999	0.000
F14.8 Other mental and behavioural disorders	0.001	0.999	0.000
F14.7 Residual and late-onset psychotic disorder	0.001	0.999	0.000
F14.6 Amnesic syndrome	0.001	0.999	0.000
F14.5 Psychotic disorder	0.001	0.999	0.000
F14.4 Withdrawal state with delirium	0.001	0.999	0.000
F14.3 Withdrawal state	0.001	0.999	0.000
F14.2 Dependence syndrome	0.001	0.999	0.000
F14.0 Acute intoxication	0.001	0.999	0.000
T38.1 Thyroid hormones and substitutes	0.001	0.999	0.000
T39.4 Antirheumatics, not elsewhere classified	0.001	0.999	0.000
T39.2 Pyrazolone derivatives	0.001	0.999	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.999	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
T47.7 Emetics	0.001	0.999	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.999	0.000
T47.5 Digestants	0.001	0.999	0.000
T47.4 Other laxatives	0.001	0.999	0.000
T47.3 Saline and osmotic laxatives	0.001	0.999	0.000
T47.2 Stimulant laxatives	0.001	0.999	0.000
T47.0 Histamine H(2)-receptor antagonists	0.001	0.999	0.000
T95 Sequelae of burns, corrosions and frostbite	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations