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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6511720
log Bayes Factor = 79.2472
Chromosome 19   position 11,202,306  (GRCh37) Explore rs6511720 on Ensembl!
Variant rs6511720 is listed in the   GWAS Catalog   ⇪
Variant rs6511720 is part of Cluster X0034

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.003 0.997
E78.5 Hyperlipidaemia, unspecified
0.000 0.005 0.995
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.005 0.995
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.013 0.987
I71 Aortic aneurysm and dissection
0.000 0.014 0.986
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.014 0.986
I20.0 Unstable angina
0.000 0.017 0.983
Chapter IX Diseases of the circulatory system
0.000 0.028 0.972
I73 Other peripheral vascular diseases
0.000 0.031 0.969
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.044 0.956
I22 Subsequent myocardial infarction
0.000 0.051 0.949
I73.0 Raynaud's syndrome
0.000 0.080 0.920
I73.9 Peripheral vascular disease, unspecified
0.000 0.092 0.908
I05-I09 Chronic rheumatic heart diseases
0.000 0.126 0.874
I25.3 Aneurysm of heart
0.000 0.132 0.868
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.134 0.866
I24 Other acute ischaemic heart diseases
0.000 0.139 0.861
I77 Other disorders of arteries and arterioles
0.000 0.139 0.861
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.144 0.856
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.149 0.851
I20.8 Other forms of angina pectoris
0.000 0.150 0.850
I08 Multiple valve diseases
0.000 0.150 0.850
I21.9 Acute myocardial infarction, unspecified
0.000 0.151 0.849
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.160 0.840
I22.8 Subsequent myocardial infarction of other sites
0.000 0.167 0.833
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.179 0.821
I21.4 Acute subendocardial myocardial infarction
0.000 0.184 0.816
I20.1 Angina pectoris with documented spasm
0.000 0.190 0.810
I77.1 Stricture of artery
0.000 0.190 0.810
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.199 0.801
I74 Arterial embolism and thrombosis
0.000 0.230 0.770
E78.8 Other disorders of lipoprotein metabolism
0.000 0.234 0.766
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.235 0.765
I72 Other aneurysm
0.000 0.245 0.755
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.247 0.753
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.271 0.729
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.274 0.726
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.275 0.725
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.286 0.714
E78.6 Lipoprotein deficiency
0.000 0.286 0.713
E78.3 Hyperchylomicronaemia
0.000 0.286 0.713
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.293 0.707
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.293 0.707
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.293 0.707
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.293 0.707
I00-I02 Acute rheumatic fever
0.000 0.303 0.697
I77.0 Arteriovenous fistula, acquired
0.000 0.304 0.696
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.305 0.695
I08.8 Other multiple valve diseases
0.000 0.306 0.694
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.307 0.693
I72.4 Aneurysm of artery of lower extremity
0.000 0.317 0.683
E78.2 Mixed hyperlipidaemia
0.000 0.318 0.682
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.320 0.680
I25.5 Ischaemic cardiomyopathy
0.000 0.327 0.673
E78.4 Other hyperlipidaemia
0.000 0.330 0.670
E78.1 Pure hyperglyceridaemia
0.000 0.333 0.666
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.345 0.655
I73.8 Other specified peripheral vascular diseases
0.000 0.348 0.652
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.358 0.642
I07 Rheumatic tricuspid valve diseases
0.000 0.360 0.640
Z95.2 Presence of prosthetic heart valve
0.000 0.364 0.636
I70 Atherosclerosis
0.000 0.365 0.635
I06 Rheumatic aortic valve diseases
0.000 0.373 0.627
I08.0 Disorders of both mitral and aortic valves
0.000 0.380 0.620
I24.1 Dressler's syndrome
0.000 0.383 0.617
I77.5 Necrosis of artery
0.000 0.383 0.617
I77.4 Coeliac artery compression syndrome
0.000 0.383 0.617
I77.3 Arterial fibromuscular dysplasia
0.000 0.383 0.617
I77.2 Rupture of artery
0.000 0.383 0.617
I25.4 Coronary artery aneurysm
0.000 0.384 0.616
I08.9 Multiple valve disease, unspecified
0.000 0.390 0.610
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.394 0.605
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.399 0.601
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.413 0.587
Z95.3 Presence of xenogenic heart valve
0.000 0.415 0.585
I74.8 Embolism and thrombosis of other arteries
0.000 0.417 0.583
I78 Diseases of capillaries
0.000 0.421 0.579
I09 Other rheumatic heart diseases
0.000 0.424 0.576
I77.8 Other specified disorders of arteries and arterioles
0.000 0.434 0.566
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.440 0.559
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.447 0.553
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.448 0.552
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.448 0.552
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.452 0.548
I79.1 Aortitis in diseases classified elsewhere
0.000 0.452 0.548
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.452 0.548
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.458 0.542
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.458 0.542
I72.2 Aneurysm of renal artery
0.000 0.458 0.542
I72.1 Aneurysm of artery of upper extremity
0.000 0.458 0.542
I72.3 Aneurysm of iliac artery
0.000 0.468 0.532
I72.9 Aneurysm of unspecified site
0.000 0.483 0.517
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.485 0.515
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
Z95.0 Presence of cardiac pacemaker
0.000 0.486 0.514
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.489 0.511
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.493 0.507
I71.0 Dissection of aorta [any part]
0.000 0.494 0.506
I02 Rheumatic chorea
0.000 0.500 0.500
I01 Rheumatic fever with heart involvement
0.000 0.500 0.500
I00 Rheumatic fever without mention of heart involvement
0.000 0.500 0.500
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.500 0.499
I77.6 Arteritis, unspecified
0.000 0.510 0.490
I07.1 Tricuspid insufficiency
0.000 0.527 0.473
I99 Other and unspecified disorders of circulatory system
0.000 0.527 0.473
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.531 0.468
I07.9 Tricuspid valve disease, unspecified
0.000 0.541 0.459
I07.8 Other tricuspid valve diseases
0.000 0.541 0.459
I07.2 Tricuspid stenosis with insufficiency
0.000 0.541 0.459
I07.0 Tricuspid stenosis
0.000 0.541 0.459
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.542 0.458
I72.8 Aneurysm of other specified arteries
0.000 0.543 0.457
I70.9 Generalised and unspecified atherosclerosis
0.000 0.544 0.455
I70.8 Atherosclerosis of other arteries
0.000 0.544 0.455
I72.0 Aneurysm of carotid artery
0.000 0.546 0.454
I74.5 Embolism and thrombosis of iliac artery
0.000 0.548 0.452
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.550 0.449
I06.8 Other rheumatic aortic valve diseases
0.000 0.550 0.449
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.550 0.449
I06.1 Rheumatic aortic insufficiency
0.000 0.550 0.449
I06.0 Rheumatic aortic stenosis
0.000 0.550 0.449
Z95.4 Presence of other heart-valve replacement
0.000 0.554 0.446
I24.8 Other forms of acute ischaemic heart disease
0.000 0.557 0.443
I70.1 Atherosclerosis of renal artery
0.000 0.561 0.439
I78.8 Other diseases of capillaries
0.000 0.574 0.426
I30-I52 Other forms of heart disease
0.000 0.582 0.418
I78.9 Disease of capillaries, unspecified
0.000 0.585 0.415
I09.8 Other specified rheumatic heart diseases
0.000 0.587 0.413
I09.2 Chronic rheumatic pericarditis
0.000 0.587 0.413
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.587 0.413
I09.0 Rheumatic myocarditis
0.000 0.587 0.413
I38 Endocarditis, valve unspecified
0.000 0.600 0.400
I35 Nonrheumatic aortic valve disorders
0.000 0.611 0.389
I70.0 Atherosclerosis of aorta
0.000 0.613 0.386
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.618 0.382
I95 Hypotension
0.000 0.624 0.376
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.630 0.370
I35.0 Aortic (valve) stenosis
0.000 0.632 0.368
I09.9 Rheumatic heart disease, unspecified
0.000 0.637 0.362
I28 Other diseases of pulmonary vessels
0.000 0.639 0.360
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.641 0.358
I01.8 Other acute rheumatic heart disease
0.000 0.641 0.358
I01.2 Acute rheumatic myocarditis
0.000 0.641 0.358
I01.1 Acute rheumatic endocarditis
0.000 0.641 0.358
I01.0 Acute rheumatic pericarditis
0.000 0.641 0.358
I02.9 Rheumatic chorea without heart involvement
0.000 0.641 0.358
I02.0 Rheumatic chorea with heart involvement
0.000 0.641 0.358
I49 Other cardiac arrhythmias
0.000 0.657 0.343
I30 Acute pericarditis
0.000 0.671 0.329
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.673 0.327
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.673 0.327
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.673 0.327
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.673 0.327
I95.2 Hypotension due to drugs
0.000 0.679 0.321
I78.1 Naevus, nonneoplastic
0.000 0.680 0.320
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.685 0.315
I51 Complications and ill-defined descriptions of heart disease
0.000 0.687 0.313
I26 Pulmonary embolism
0.000 0.687 0.313
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.692 0.307
I49.0 Ventricular fibrillation and flutter
0.000 0.693 0.307
I33 Acute and subacute endocarditis
0.000 0.694 0.306
I52 Other heart disorders in diseases classified elsewhere
0.000 0.700 0.300
I48 Atrial fibrillation and flutter
0.000 0.700 0.300
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.700 0.300
I41 Myocarditis in diseases classified elsewhere
0.000 0.700 0.300
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.700 0.300
I32 Pericarditis in diseases classified elsewhere
0.000 0.700 0.300
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.702 0.298
I37 Pulmonary valve disorders
0.000 0.703 0.297
I49.8 Other specified cardiac arrhythmias
0.000 0.709 0.291
I95.1 Orthostatic hypotension
0.000 0.709 0.291
I35.1 Aortic (valve) insufficiency
0.000 0.710 0.289
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.713 0.286
I44 Atrioventricular and left bundle-branch block
0.000 0.716 0.284
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.716 0.284
I40 Acute myocarditis
0.000 0.717 0.282
I30.9 Acute pericarditis, unspecified
0.000 0.719 0.281
I47 Paroxysmal tachycardia
0.000 0.720 0.280
I27 Other pulmonary heart diseases
0.000 0.722 0.278
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.723 0.277
I95.8 Other hypotension
0.000 0.726 0.273
I36 Nonrheumatic tricuspid valve disorders
0.000 0.727 0.272
I95.0 Idiopathic hypotension
0.000 0.729 0.271
I35.8 Other aortic valve disorders
0.000 0.730 0.270
I10-I15 Hypertensive diseases
0.000 0.732 0.268
I35.9 Aortic valve disorder, unspecified
0.000 0.733 0.267
I49.9 Cardiac arrhythmia, unspecified
0.000 0.734 0.266
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.741 0.258
I28.1 Aneurysm of pulmonary artery
0.000 0.741 0.258
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.741 0.258
I49.4 Other and unspecified premature depolarisation
0.000 0.742 0.258
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.746 0.254
I51.9 Heart disease, unspecified
0.000 0.747 0.253
I28.8 Other specified diseases of pulmonary vessels
0.000 0.747 0.253
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.748 0.251
I51.6 Cardiovascular disease, unspecified
0.000 0.749 0.251
I05 Rheumatic mitral valve diseases
0.001 0.754 0.245
I49.2 Junctional premature depolarisation
0.000 0.754 0.246
I44.7 Left bundle-branch block, unspecified
0.000 0.755 0.245
I49.1 Atrial premature depolarisation
0.000 0.756 0.244
I30.8 Other forms of acute pericarditis
0.000 0.764 0.236
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.764 0.236
I51.0 Cardiac septal defect, acquired
0.000 0.766 0.234
I27.8 Other specified pulmonary heart diseases
0.000 0.766 0.234
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.771 0.229
I33.0 Acute and subacute infective endocarditis
0.000 0.774 0.226
I51.5 Myocardial degeneration
0.000 0.775 0.225
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.775 0.225
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.775 0.225
I51.8 Other ill-defined heart diseases
0.000 0.776 0.224
I33.9 Acute endocarditis, unspecified
0.000 0.780 0.220
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.781 0.219
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.785 0.215
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.785 0.215
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.785 0.215
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.785 0.215
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.785 0.215
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.785 0.215
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.785 0.215
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.785 0.215
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.785 0.215
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.785 0.215
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.785 0.215
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.785 0.215
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.785 0.215
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.785 0.215
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.785 0.215
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.785 0.215
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.785 0.215
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.785 0.215
I48.4 Atypical atrial flutter
0.000 0.785 0.215
I48.3 Typical atrial flutter
0.000 0.785 0.215
I48.2 Chronic atrial fibrillation
0.000 0.785 0.215
I48.1 Persistent atrial fibrillation
0.000 0.785 0.215
I48.0 Paroxysmal atrial fibrillation
0.000 0.785 0.215
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.785 0.215
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.785 0.215
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.785 0.215
I37.9 Pulmonary valve disorder, unspecified
0.000 0.787 0.213
I37.8 Other pulmonary valve disorders
0.000 0.787 0.213
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.787 0.213
I37.0 Pulmonary valve stenosis
0.000 0.787 0.213
I37.1 Pulmonary valve insufficiency
0.000 0.790 0.210
I47.2 Ventricular tachycardia
0.000 0.790 0.210
I70.00 Atherosclerosis of aorta (without gangrene)
0.001 0.792 0.208
I30.1 Infective pericarditis
0.000 0.793 0.207
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.794 0.205
I97.0 Postcardiotomy syndrome
0.000 0.794 0.205
I44.3 Other and unspecified atrioventricular block
0.000 0.794 0.206
I51.4 Myocarditis, unspecified
0.000 0.795 0.205
I44.5 Left posterior fascicular block
0.000 0.796 0.204
I44.4 Left anterior fascicular block
0.000 0.796 0.204
I40.9 Acute myocarditis, unspecified
0.000 0.797 0.203
I40.8 Other acute myocarditis
0.000 0.797 0.203
I40.1 Isolated myocarditis
0.000 0.797 0.203
I15 Secondary hypertension
0.000 0.797 0.203
I27.9 Pulmonary heart disease, unspecified
0.000 0.797 0.202
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.799 0.201
I31 Other diseases of pericardium
0.000 0.800 0.200
I27.1 Kyphoscoliotic heart disease
0.000 0.800 0.200
I44.6 Other and unspecified fascicular block
0.000 0.803 0.197
I44.2 Atrioventricular block, complete
0.000 0.804 0.196
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.804 0.195
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.804 0.195
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.804 0.195
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.804 0.195
I13 Hypertensive heart and renal disease
0.000 0.808 0.192
I45 Other conduction disorders
0.000 0.809 0.191
I47.0 Reentry ventricular arrhythmia
0.000 0.811 0.189
I40.0 Infective myocarditis
0.000 0.815 0.185
I46 Cardiac arrest
0.000 0.815 0.185
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.819 0.180
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.819 0.180
I98.0 Cardiovascular syphilis
0.000 0.819 0.180
I44.1 Atrioventricular block, second degree
0.000 0.821 0.179
I05.8 Other mitral valve diseases
0.001 0.823 0.176
I50 Heart failure
0.000 0.824 0.176
I45.2 Bifascicular block
0.000 0.825 0.175
I49.3 Ventricular premature depolarisation
0.000 0.827 0.173
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.832 0.168
I27.2 Other secondary pulmonary hypertension
0.000 0.833 0.167
I97.1 Other functional disturbances following cardiac surgery
0.000 0.834 0.166
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.834 0.165
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.837 0.163
I12 Hypertensive renal disease
0.000 0.837 0.163
I44.0 Atrioventricular block, first degree
0.000 0.842 0.158
I15.1 Hypertension secondary to other renal disorders
0.000 0.844 0.156
I05.2 Mitral stenosis with insufficiency
0.001 0.844 0.155
I47.1 Supraventricular tachycardia
0.000 0.845 0.155
I11 Hypertensive heart disease
0.000 0.851 0.148
I45.9 Conduction disorder, unspecified
0.000 0.854 0.146
I15.9 Seconday hypertension, unspecified
0.000 0.854 0.145
I15.8 Other secondary hypertension
0.000 0.854 0.145
I15.2 Hypertension secondary to endocrine disorders
0.000 0.854 0.145
I15.0 Renovascular hypertension
0.000 0.854 0.145
I31.8 Other specified diseases of pericardium
0.000 0.856 0.144
I31.2 Haemopericardium, not elsewhere classified
0.000 0.856 0.144
I31.1 Chronic constrictive pericarditis
0.000 0.856 0.144
I31.0 Chronic adhesive pericarditis
0.000 0.856 0.144
I34 Nonrheumatic mitral valve disorders
0.000 0.856 0.144
I50.1 Left ventricular failure
0.000 0.859 0.141
I05.0 Mitral stenosis
0.001 0.861 0.138
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.862 0.138
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.862 0.138
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.862 0.138
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.862 0.138
I45.0 Right fascicular block
0.000 0.863 0.137
I49.5 Sick sinus syndrome
0.000 0.864 0.136
I46.1 Sudden cardiac death, so described
0.000 0.867 0.133
I45.8 Other specified conduction disorders
0.000 0.869 0.131
I05.9 Mitral valve disease, unspecified
0.001 0.870 0.129
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.872 0.128
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.001 0.872 0.127
I31.3 Pericardial effusion (noninflammatory)
0.000 0.876 0.123
I12.0 Hypertensive renal disease with renal failure
0.000 0.879 0.121
I45.6 Preexcitation syndrome
0.000 0.881 0.119
I05.1 Rheumatic mitral insufficiency
0.001 0.886 0.112
I46.9 Cardiac arrest, unspecified
0.000 0.889 0.111
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.892 0.108
I45.4 Nonspecific intraventricular block
0.000 0.894 0.105
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.896 0.104
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.897 0.103
I45.5 Other specified heart block
0.000 0.898 0.102
I51.7 Cardiomegaly
0.000 0.903 0.097
I45.3 Trifascicular block
0.000 0.903 0.096
I45.1 Other and unspecified right bundle-branch block
0.000 0.904 0.096
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.905 0.095
I50.9 Heart failure, unspecified
0.000 0.909 0.091
I31.9 Disease of pericardium, unspecified
0.000 0.915 0.085
I34.1 Mitral (valve) prolapse
0.000 0.916 0.084
I12.9 Hypertensive renal disease without renal failure
0.000 0.921 0.079
I46.0 Cardiac arrest with successful resuscitation
0.000 0.932 0.068
I27.0 Primary pulmonary hypertension
0.001 0.936 0.063
I95.9 Hypotension, unspecified
0.000 0.938 0.062
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.940 0.059
Y83.2 Surgical operation with anastomosis, bypass or graft
0.000 0.956 0.044
I42 Cardiomyopathy
0.000 0.960 0.039
I50.0 Congestive heart failure
0.000 0.967 0.033
I34.0 Mitral (valve) insufficiency
0.000 0.969 0.031
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.971 0.028
I42.5 Other restrictive cardiomyopathy
0.000 0.971 0.028
I42.4 Endocardial fibroelastosis
0.000 0.971 0.028
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.971 0.028
E70-E90 Metabolic disorders
0.000 0.972 0.028
I60-I69 Cerebrovascular diseases
0.001 0.973 0.026
E83.5 Disorders of calcium metabolism
0.000 0.974 0.026
E85 Amyloidosis
0.000 0.975 0.025
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.000 0.976 0.024
I42.8 Other cardiomyopathies
0.000 0.976 0.023
E83 Disorders of mineral metabolism
0.000 0.976 0.024
I62 Other nontraumatic intracranial haemorrhage
0.001 0.977 0.022
I42.2 Other hypertrophic cardiomyopathy
0.000 0.977 0.022
E85.9 Amyloidosis, unspecified
0.000 0.978 0.022
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.979 0.021
I42.0 Dilated cardiomyopathy
0.000 0.979 0.021
I42.6 Alcoholic cardiomyopathy
0.001 0.979 0.021
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.979 0.021
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.001 0.979 0.020
E84 Cystic fibrosis
0.000 0.979 0.021
E79 Disorders of purine and pyrimidine metabolism
0.000 0.979 0.021
E77 Disorders of glycoprotein metabolism
0.000 0.979 0.021
E76 Disorders of glycosaminoglycan metabolism
0.000 0.979 0.021
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.979 0.021
E72 Other disorders of amino-acid metabolism
0.000 0.979 0.021
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.979 0.021
E70 Disorders of aromatic amino-acid metabolism
0.000 0.979 0.021
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.979 0.021
E85.4 Organ-limited amyloidosis
0.000 0.979 0.021
I68 Cerebrovascular disorders in diseases classified elsewhere
0.001 0.980 0.019
E73 Lactose intolerance
0.000 0.981 0.019
E85.8 Other amyloidosis
0.000 0.982 0.018
E85.3 Secondary systemic amyloidosis
0.000 0.982 0.018
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.982 0.018
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.982 0.018
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.982 0.018
E74 Other disorders of carbohydrate metabolism
0.000 0.982 0.018
O80.9 Single spontaneous delivery, unspecified
0.018 0.982 0.000
E88 Other metabolic disorders
0.000 0.982 0.018
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.982 0.018
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.983 0.017
E83.8 Other disorders of mineral metabolism
0.000 0.983 0.017
E83.2 Disorders of zinc metabolism
0.000 0.983 0.017
E83.0 Disorders of copper metabolism
0.000 0.983 0.017
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.001 0.983 0.016
I62.1 Nontraumatic extradural haemorrhage
0.001 0.983 0.016
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.983 0.017
M50 Cervical disk disorders
0.017 0.983 0.000
O80.0 Spontaneous vertex delivery
0.017 0.983 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.983 0.016
M50.0 Cervical disk disorder with myelopathy
0.016 0.984 0.000
M50-M54 Other dorsopathies
0.016 0.984 0.000
I67.9 Cerebrovascular disease, unspecified
0.016 0.984 0.000
O80 Single spontaneous delivery
0.016 0.984 0.000
M51 Other intervertebral disk disorders
0.015 0.985 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.001 0.985 0.015
I65.8 Occlusion and stenosis of other precerebral artery
0.001 0.985 0.015
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.001 0.985 0.015
I65.1 Occlusion and stenosis of basilar artery
0.001 0.985 0.015
I65.0 Occlusion and stenosis of vertebral artery
0.001 0.985 0.015
M51.2 Other specified intervertebral disk displacement
0.015 0.985 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.985 0.015
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.985 0.015
E70.3 Albinism
0.000 0.985 0.015
E70.2 Disorders of tyrosine metabolism
0.000 0.985 0.015
E70.1 Other hyperphenylalaninaemias
0.000 0.985 0.015
E70.0 Classical phenylketonuria
0.000 0.985 0.015
E71.3 Disorders of fatty-acid metabolism
0.000 0.985 0.015
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.985 0.015
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.985 0.015
E71.0 Maple-syrup-urine disease
0.000 0.985 0.015
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.985 0.015
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.985 0.015
E72.5 Disorders of glycine metabolism
0.000 0.985 0.015
E72.4 Disorders of ornithine metabolism
0.000 0.985 0.015
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.985 0.015
E72.2 Disorders of urea cycle metabolism
0.000 0.985 0.015
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.985 0.015
E72.0 Disorders of amino-acid transport
0.000 0.985 0.015
E75.6 Lipid storage disorder, unspecified
0.000 0.985 0.015
E75.5 Other lipid storage disorders
0.000 0.985 0.015
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.985 0.015
E75.3 Sphingolipidosis, unspecified
0.000 0.985 0.015
E75.2 Other sphingolipidosis
0.000 0.985 0.015
E75.1 Other gangliosidosis
0.000 0.985 0.015
E75.0 GM2 gangliosidosis
0.000 0.985 0.015
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.985 0.015
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.985 0.015
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.985 0.015
E76.2 Other mucopolysaccharidoses
0.000 0.985 0.015
E76.1 Mucopolysaccharidosis, type II
0.000 0.985 0.015
E76.0 Mucopolysaccharidosis, type I
0.000 0.985 0.015
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.985 0.015
E77.8 Other disorders of glycoprotein metabolism
0.000 0.985 0.015
E77.1 Defects in glycoprotein degradation
0.000 0.985 0.015
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.985 0.015
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.985 0.015
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.985 0.015
E79.1 Lesch-Nyhan syndrome
0.000 0.985 0.015
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.985 0.015
E84.9 Cystic fibrosis, unspecified
0.000 0.985 0.015
E84.8 Cystic fibrosis with other manifestations
0.000 0.985 0.015
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.985 0.015
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.985 0.015
M50.2 Other cervical disk displacement
0.015 0.985 0.000
M53 Other dorsopathies, not elsewhere classified
0.015 0.985 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.001 0.985 0.014
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.001 0.985 0.014
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.001 0.985 0.014
I68.0 Cerebral amyloid angiopathy
0.001 0.985 0.014
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.014 0.986 0.000
E73.8 Other lactose intolerance
0.000 0.986 0.013
E73.1 Secondary lactase deficiency
0.000 0.986 0.013
E73.0 Congenital lactase deficiency
0.000 0.986 0.013
E83.3 Disorders of phosphorus metabolism
0.000 0.986 0.013
M47.99 Spondylosis, unspecified (Site unspecified)
0.014 0.986 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.987 0.013
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.987 0.013
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.987 0.013
E74.2 Disorders of galactose metabolism
0.000 0.987 0.013
E74.1 Disorders of fructose metabolism
0.000 0.987 0.013
E74.0 Glycogen storage disease
0.000 0.987 0.013
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.001 0.987 0.012
M50.3 Other cervical disk degeneration
0.013 0.987 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.013 0.987 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.013 0.987 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.987 0.013
E88.8 Other specified metabolic disorders
0.000 0.987 0.013
E88.3 Tumour lysis syndrome
0.000 0.987 0.013
E88.2 Lipomatosis, not elsewhere classified
0.000 0.987 0.013
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.987 0.013
E80.6 Other disorders of bilirubin metabolism
0.000 0.987 0.013
E80.5 Crigler-Najjar syndrome
0.000 0.987 0.013
E80.3 Defects of catalase and peroxydase
0.000 0.987 0.013
E80.1 Porphyria cutanea tarda
0.000 0.987 0.013
E80.0 Hereditary erythropoietic porphyria
0.000 0.987 0.013
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.987 0.013
M51.8 Other specified intervertebral disk disorders
0.013 0.987 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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