TreeWAS – Variant ID: rs6534441

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G90-G99 Other disorders of the nervous system	0.508	0.492	0.000
G91 Hydrocephalus	0.502	0.498	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.496	0.504	0.000
G91.9 Hydrocephalus, unspecified	0.496	0.504	0.000
G96 Other disorders of central nervous system	0.491	0.509	0.000
G90 Disorders of autonomic nervous system	0.472	0.528	0.000
G96.0 Cerebrospinal fluid leak	0.471	0.529	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.464	0.536	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.460	0.540	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.454	0.546	0.000
G91.1 Obstructive hydrocephalus	0.414	0.586	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.414	0.586	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.409	0.591	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.408	0.592	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.397	0.603	0.000
G96.8 Other specified disorders of central nervous system	0.388	0.612	0.000
G90.2 Horner's syndrome	0.382	0.618	0.000
G91.8 Other hydrocephalus	0.368	0.632	0.000
G96.9 Disorder of central nervous system, unspecified	0.365	0.635	0.000
G91.2 Normal-pressure hydrocephalus	0.364	0.636	0.000
G92 Toxic encephalopathy	0.364	0.636	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.359	0.641	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.359	0.641	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.355	0.644	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.355	0.644	0.000
G90.8 Other disorders of autonomic nervous system	0.352	0.647	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.350	0.650	0.000
G95 Other diseases of spinal cord	0.342	0.658	0.000
G90.4 Autonomic dysreflexia	0.339	0.661	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.339	0.661	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.330	0.670	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.330	0.670	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.328	0.672	0.000
G91.0 Communicating hydrocephalus	0.328	0.672	0.000
G90.3 Multisystem degeneration	0.315	0.685	0.000
G95.1 Vascular myelopathies	0.273	0.727	0.000
G93 Other disorders of brain	0.263	0.737	0.000
G93.4 Encephalopathy, unspecified	0.253	0.747	0.000
G95.2 Cord compression, unspecified	0.236	0.764	0.000
G95.0 Syringomyelia and syringobulbia	0.236	0.764	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.235	0.765	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.235	0.765	0.000
G95.8 Other specified diseases of spinal cord	0.235	0.765	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.234	0.766	0.000
G95.9 Disease of spinal cord, unspecified	0.218	0.782	0.000
G97.8 Other postprocedural disorders of nervous system	0.210	0.789	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.206	0.794	0.000
G94.1 Hydrocephalus in neoplastic disease	0.200	0.800	0.000
G93.5 Compression of brain	0.190	0.809	0.000
G93.7 Reye's syndrome	0.188	0.811	0.000
G93.9 Disorder of brain, unspecified	0.176	0.824	0.000
G93.0 Cerebral cysts	0.175	0.824	0.000
G93.6 Cerebral oedema	0.169	0.831	0.000
G93.8 Other specified disorders of brain	0.118	0.882	0.000
G93.2 Benign intracranial hypertension	0.091	0.909	0.001
G93.3 Postviral fatigue syndrome	0.051	0.949	0.000
Y43.3 Other antineoplastic drugs	0.039	0.961	0.000
Y43 Primarily systemic agents	0.036	0.964	0.000
Y43.0 Antiallergic and antiemetic drugs	0.031	0.969	0.000
Y43.1 Antineoplastic antimetabolites	0.031	0.969	0.000
Y43.4 Immunosuppressive agents	0.030	0.970	0.000
Y43.2 Antineoplastic natural products	0.027	0.973	0.000
Y43.9 Primarily systemic agent, unspecified	0.026	0.974	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.026	0.974	0.000
Y43.6 Enzymes, not elsewhere classified	0.026	0.974	0.000
Y43.5 Acidifying and alkalising agents	0.026	0.974	0.000
R41.0 Disorientation, unspecified	0.021	0.979	0.000
Y40.3 Macrolides	0.018	0.982	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.982	0.018
Y40 Systemic antibiotics	0.018	0.982	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.017	0.983	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.017	0.983	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.016	0.984	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.016	0.984	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.984	0.016
Y40.8 Other systemic antibiotics	0.015	0.985	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.985	0.015
Y48 Anaesthetics and therapeutic gases	0.014	0.986	0.000
Y59 Other and unspecified vaccines and biological substances	0.014	0.986	0.000
Y40.0 Penicillins	0.014	0.986	0.000
Y40.5 Aminoglycosides	0.014	0.986	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.014	0.986	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.014	0.986	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.014	0.986	0.000
Y40.2 Chloramphenicol group	0.013	0.987	0.000
Y40.4 Tetracyclines	0.013	0.987	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.013	0.987	0.000
Y40.7 Antifungal antibiotics, systemically used	0.013	0.987	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.013	0.987	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.013	0.987	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.013	0.987	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.013	0.987	0.000
Y51.0 Anticholinesterase agents	0.013	0.987	0.000
Y48.2 Other and unspecified general anaesthetics	0.012	0.987	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.012	0.988	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.012	0.988	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.012	0.988	0.000
Y40.6 Rifamycins	0.012	0.988	0.000
Y58 Bacterial vaccines	0.012	0.988	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.012	0.988	0.000
Y42.5 Other oestrogens and progestogens	0.012	0.988	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.012	0.988	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.012	0.988	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.012	0.988	0.000
Y59.0 Viral vaccines	0.012	0.988	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.011	0.989	0.000
Y47.1 Benzodiazepines	0.011	0.989	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.011	0.989	0.000
Y42.9 Other and unspecified hormone antagonists	0.011	0.989	0.000
Y48.3 Local anaesthetics	0.011	0.989	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.011	0.989	0.000
Y42.2 Antithyroid drugs	0.011	0.989	0.000
Y48.5 Therapeutic gases	0.010	0.989	0.000
Y48.1 Parenteral anaesthetics	0.010	0.989	0.000
Y48.0 Inhaled anaesthetics	0.010	0.989	0.000
Y41.0 Sulphonamides	0.010	0.990	0.000
Y57 Other and unspecified drugs and medicaments	0.010	0.990	0.000
Y59.9 Vaccine or biological substance, unspecified	0.010	0.990	0.000
Y59.8 Other specified vaccines and biological substances	0.010	0.990	0.000
Y59.2 Protozoal vaccines	0.010	0.990	0.000
Y59.1 Rickettsial vaccines	0.010	0.990	0.000
Y59.3 Immunoglobulin	0.010	0.990	0.000
F29 Unspecified nonorganic psychosis	0.000	0.990	0.010
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.010	0.990	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.010	0.990	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.010	0.990	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.010	0.990	0.000
Y47.4 Bromine compounds	0.010	0.990	0.000
Y47.3 Paraldehyde	0.010	0.990	0.000
Y47.2 Chloral derivatives	0.010	0.990	0.000
Y47.0 Barbiturates, not elsewhere classified	0.010	0.990	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.010	0.990	0.000
Y48.4 Anaesthetic, unspecified	0.010	0.990	0.000
Y40.9 Systemic antibiotic, unspecified	0.010	0.990	0.000
Y41.5 Antiviral drugs	0.010	0.990	0.000
Y54.0 Mineralocorticoids	0.009	0.990	0.000
Y52 Agents primarily affecting the cardiovascular system	0.010	0.990	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.009	0.991	0.000
Y41.4 Anthelminthics	0.009	0.991	0.000
Y41.3 Other antiprotozoal drugs	0.009	0.991	0.000
Y42.7 Androgens and anabolic congeners	0.009	0.991	0.000
Y54.3 Benzothiadiazine derivatives	0.009	0.991	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.991	0.009
Y50.9 Central nervous system stimulant, unspecified	0.009	0.991	0.000
Y50.8 Other central nervous system stimulants	0.009	0.991	0.000
Y50.1 Opioid receptor antagonists	0.009	0.991	0.000
Y50.0 Analeptics	0.009	0.991	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.009	0.991	0.000
Y55.5 Anticommon cold drugs	0.009	0.991	0.000
Y55.3 Antitussives	0.009	0.991	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.009	0.991	0.000
Y55.0 Oxytocic drugs	0.009	0.991	0.000
Y58.9 Other and unspecified bacterial vaccines	0.009	0.991	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.009	0.991	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.009	0.991	0.000
Y58.5 Diphtheria vaccine	0.009	0.991	0.000
Y58.4 Tetanus vaccine	0.009	0.991	0.000
Y58.3 Plague vaccine	0.009	0.991	0.000
Y58.2 Cholera vaccine	0.009	0.991	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.009	0.991	0.000
Y54.5 Other diuretics	0.009	0.991	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.009	0.991	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.009	0.991	0.000
F22 Persistent delusional disorders	0.000	0.991	0.009
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.009	0.991	0.000
Y54.9 Mineral salts, not elsewhere classified	0.009	0.991	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.009	0.991	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.009	0.991	0.000
A49.0 Staphylococcal infection, unspecified	0.009	0.991	0.000
Y44 Agents primarily affecting blood constituents	0.009	0.991	0.000
Y55.4 Expectorants	0.009	0.991	0.000
Y42.4 Oral contraceptives	0.009	0.991	0.000
Y58.0 BCG vaccine	0.008	0.991	0.000
F22.0 Delusional disorder	0.000	0.991	0.009
N60.4 Mammary duct ectasia	0.009	0.991	0.000
Y54.7 Agents affecting calcification	0.008	0.991	0.000
Y54.4 Loop [high-ceiling] diuretics	0.008	0.992	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.008	0.992	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.992	0.008
Y49.9 Psychotropic drug, unspecified	0.008	0.992	0.000
Y49.7 Psychostimulants with abuse potential	0.008	0.992	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.008	0.992	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.008	0.992	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.992	0.000
C45.7 Mesothelioma of other sites	0.000	0.992	0.008
Y41.1 Antimycobacterial drugs	0.008	0.992	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.008	0.992	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.008	0.992	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.008	0.992	0.000
Y56.9 Topical agent, unspecified	0.008	0.992	0.000
Y56.8 Other topical agents	0.008	0.992	0.000
Y56.7 Dental drugs, topically applied	0.008	0.992	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.008	0.992	0.000
Y56.5 Ophthalmological drugs and preparations	0.008	0.992	0.000
Y56.2 Local astringents and local detergents	0.008	0.992	0.000
Y56.1 Antipruritics	0.008	0.992	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.008	0.992	0.000
F25 Schizoaffective disorders	0.000	0.992	0.008
Y49.0 Tricyclic and tetracyclic antidepressants	0.008	0.992	0.000
Y57.6 Other diagnostic agents	0.008	0.992	0.000
Y42.1 Thyroid hormones and substitutes	0.007	0.992	0.000
Y56.3 Emollients, demulcents and protectants	0.008	0.992	0.000
F23 Acute and transient psychotic disorders	0.000	0.992	0.008
Y49.5 Other antipsychotics and neuroleptics	0.008	0.992	0.000
Y57.7 Vitamins, not elsewhere classified	0.008	0.992	0.000
Y57.4 Pharmaceutical excipients	0.008	0.992	0.000
Y57.3 Alcohol deterrents	0.008	0.992	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.008	0.992	0.000
Y57.1 Lipotropic drugs	0.008	0.992	0.000
Y57.0 Appetite depressants [anorectics]	0.008	0.992	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.008	0.992	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.008	0.992	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.007	0.992	0.000
Y45.2 Propionic acid derivatives	0.008	0.992	0.000
Y57.9 Drug or medicament, unspecified	0.007	0.992	0.000
Y54.8 Agents affecting uric acid metabolism	0.007	0.993	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.007	0.993	0.000
Y52.1 Calcium-channel blockers	0.007	0.993	0.000
Y52.7 Peripheral vasodilators	0.007	0.993	0.000
C45 Mesothelioma	0.000	0.993	0.007
F20 Schizophrenia	0.000	0.993	0.007
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.993	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
F21 Schizotypal disorder	0.000	0.993	0.007
Y53 Agents primarily affecting the gastro-intestinal system	0.007	0.993	0.000
F22.9 Persistent delusional disorder, unspecified	0.000	0.993	0.007
F28 Other nonorganic psychotic disorders	0.000	0.993	0.007
F24 Induced delusional disorder	0.000	0.993	0.007
Y57.5 X-ray contrast media	0.007	0.993	0.000
Y49.2 Other and unspecified antidepressants	0.007	0.993	0.000
C45.0 Mesothelioma of pleura	0.000	0.993	0.007
Y44.6 Natural blood and blood products	0.007	0.993	0.000
C45.9 Mesothelioma, unspecified	0.000	0.993	0.007
F25.2 Schizoaffective disorder, mixed type	0.000	0.993	0.007
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
F22.8 Other persistent delusional disorders	0.000	0.993	0.006
F25.0 Schizoaffective disorder, manic type	0.000	0.993	0.007
Y44.5 Thrombolytic drugs	0.006	0.993	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.006	0.993	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.006	0.993	0.000
Y44.7 Plasma substitutes	0.006	0.993	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.006	0.993	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.006	0.993	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.994	0.006
F20.5 Residual schizophrenia	0.000	0.994	0.006
Y57.8 Other drugs and medicaments	0.006	0.994	0.000
Y46.5 Valproic acid	0.006	0.994	0.000
Y45.5 4-Aminophenol derivatives	0.006	0.994	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.006	0.994	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.006	0.994	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.994	0.006
Y46.2 Hydantoin derivatives	0.006	0.994	0.000
Y45.4 Antirheumatics	0.006	0.994	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.994	0.006
Y46.8 Antispasticity drugs	0.006	0.994	0.000
Y46.3 Deoxybarbiturates	0.006	0.994	0.000
Y46.1 Oxazolidinediones	0.006	0.994	0.000
Y46.0 Succinimides	0.006	0.994	0.000
Y45.8 Other analgesics and antipyretics	0.006	0.994	0.000
F25.8 Other schizoaffective disorders	0.000	0.994	0.006
F25.9 Schizoaffective disorder, unspecified	0.000	0.994	0.006
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.994	0.006
F20.2 Catatonic schizophrenia	0.000	0.994	0.006
F20.0 Paranoid schizophrenia	0.000	0.994	0.006
F23.8 Other acute and transient psychotic disorders	0.000	0.994	0.006
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.994	0.006
F20.8 Other schizophrenia	0.000	0.994	0.006
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.005	0.994	0.000
F25.1 Schizoaffective disorder, depressive type	0.000	0.994	0.005
C45.2 Mesothelioma of pericardium	0.000	0.994	0.005
C45.1 Mesothelioma of peritoneum	0.000	0.994	0.005
F20.6 Simple schizophrenia	0.000	0.994	0.005
F20.4 Postschizophrenic depression	0.000	0.994	0.005
F20.3 Undifferentiated schizophrenia	0.000	0.994	0.005
F20.1 Hebephrenic schizophrenia	0.000	0.994	0.005
Y46.7 Anti-Parkinsonism drugs	0.005	0.995	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
Y53.7 Emetics	0.005	0.995	0.000
Y53.5 Digestants	0.005	0.995	0.000
Y53.3 Saline and osmotic laxatives	0.005	0.995	0.000
Y53.0 Histamine H2-receptor antagonists	0.005	0.995	0.000
Y46.6 Other and unspecified antiepileptics	0.005	0.995	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.005	0.995	0.001
C15.5 Lower third of oesophagus	0.000	0.995	0.005
I86.4 Gastric varices	0.005	0.995	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.005	0.995	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.995	0.005
Y53.6 Antidiarrhoeal drugs	0.005	0.995	0.001
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.005	0.995	0.000
Y53.2 Stimulant laxatives	0.004	0.995	0.001
N42.1 Congestion and haemorrhage of prostate	0.000	0.995	0.005
Y44.2 Anticoagulants	0.005	0.995	0.000
N42.0 Calculus of prostate	0.000	0.995	0.005
I05 Rheumatic mitral valve diseases	0.000	0.995	0.005
Chapter VI Diseases of the nervous system	0.005	0.995	0.000
K83.8 Other specified diseases of biliary tract	0.005	0.995	0.000
T88.4 Failed or difficult intubation	0.005	0.995	0.000
G80 Infantile cerebral palsy	0.004	0.995	0.000
G80.9 Infantile cerebral palsy, unspecified	0.004	0.996	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.996	0.004
I05.0 Mitral stenosis	0.000	0.996	0.004
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.004	0.996	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.996	0.004
H59.0 Vitreous syndrome following cataract surgery	0.004	0.996	0.000
K75.9 Inflammatory liver disease, unspecified	0.004	0.996	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.001
G80.8 Other infantile cerebral palsy	0.004	0.996	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.004	0.996	0.000
D75.1 Secondary polycythaemia	0.004	0.996	0.000
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
G82 Paraplegia and tetraplegia	0.004	0.996	0.000
Y46.4 Iminostilbenes	0.003	0.996	0.001
R41 Other symptoms and signs involving cognitive functions and awareness	0.004	0.996	0.000
Y53.4 Other laxatives	0.003	0.996	0.001
I05.1 Rheumatic mitral insufficiency	0.000	0.996	0.004
G82.1 Spastic paraplegia	0.004	0.996	0.000
I05.8 Other mitral valve diseases	0.000	0.996	0.004
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.996	0.004
G80.0 Spastic cerebral palsy	0.004	0.996	0.000
G62.9 Polyneuropathy, unspecified	0.004	0.996	0.000
R41.2 Retrograde amnesia	0.004	0.996	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.996	0.004
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.996	0.004
C49.0 Connective and soft tissue of head, face and neck	0.000	0.996	0.004
F20.9 Schizophrenia, unspecified	0.000	0.996	0.004
K63.9 Disease of intestine, unspecified	0.000	0.996	0.004
N42.2 Atrophy of prostate	0.000	0.996	0.004
G80.4 Ataxic cerebral palsy	0.003	0.996	0.000
G80.3 Dyskinetic cerebral palsy	0.003	0.996	0.000
G80.2 Infantile hemiplegia	0.003	0.996	0.000
N42 Other disorders of prostate	0.000	0.996	0.004
H33.0 Retinal detachment with retinal break	0.003	0.997	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.997	0.003
H44.2 Degenerative myopia	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.003	0.997	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.003	0.997	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.997	0.003
G80.1 Spastic diplegia	0.003	0.997	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.997	0.003
K51 Ulcerative colitis	0.000	0.997	0.003
K51.4 Pseudopolyposis of colon	0.000	0.997	0.003
G70-G73 Diseases of myoneural junction and muscle	0.003	0.997	0.000
M70.22 Olecranon bursitis-Upper arm	0.003	0.997	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.997	0.003
K51.5 Mucosal proctocolitis	0.000	0.997	0.003
G35-G37 Demyelinating diseases of the central nervous system	0.003	0.997	0.000
G71 Primary disorders of muscles	0.003	0.997	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.997	0.003
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.003	0.997	0.000
U80.1 Methicillin resistant agent	0.003	0.997	0.000
G82.3 Flaccid tetraplegia	0.003	0.997	0.000
G82.0 Flaccid paraplegia	0.003	0.997	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.003	0.997	0.000
N64.8 Other specified disorders of breast	0.003	0.997	0.000
N42.3 Dysplasia of prostate	0.000	0.997	0.003
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.997	0.003
G82.5 Tetraplegia, unspecified	0.003	0.997	0.000
G82.4 Spastic tetraplegia	0.003	0.997	0.000
G62 Other polyneuropathies	0.003	0.997	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.003	0.997	0.000
N99.0 Postprocedural renal failure	0.000	0.997	0.003
G62.1 Alcoholic polyneuropathy	0.003	0.997	0.000
G20-G26 Extrapyramidal and movement disorders	0.003	0.997	0.000
I86 Varicose veins of other sites	0.003	0.997	0.000
S92.3 Fracture of metatarsal bone	0.000	0.997	0.003
A49 Bacterial infection of unspecified site	0.003	0.997	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.997	0.003
C49.5 Connective and soft tissue of pelvis	0.000	0.997	0.003
E11.4 With neurological complications	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.997	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.000	0.997	0.003
C46 Kaposi's sarcoma	0.000	0.997	0.003
G36 Other acute disseminated demyelination	0.003	0.997	0.000
G24 Dystonia	0.003	0.997	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.997	0.003
G24.3 Spasmodic torticollis	0.003	0.997	0.000
N64.5 Other signs and symptoms in breast	0.003	0.997	0.000
I24.8 Other forms of acute ischaemic heart disease	0.003	0.997	0.000
N99.2 Postprocedural adhesions of vagina	0.000	0.997	0.003
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
D22.0 Melanocytic naevi of lip	0.000	0.997	0.003
I86.1 Scrotal varices	0.003	0.997	0.000
G35 Multiple sclerosis	0.003	0.997	0.000
I85.0 Oesophageal varices with bleeding	0.003	0.997	0.000
N99.1 Postprocedural urethral stricture	0.000	0.997	0.003
Y45.1 Salicylates	0.002	0.997	0.000
G71.0 Muscular dystrophy	0.003	0.997	0.000
M75.3 Calcific tendinitis of shoulder	0.000	0.997	0.003
G25.0 Essential tremor	0.003	0.997	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.002	0.997	0.000
G30-G32 Other degenerative diseases of the nervous system	0.003	0.997	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.997	0.002
G71.9 Primary disorder of muscle, unspecified	0.002	0.997	0.000
G71.8 Other primary disorders of muscles	0.002	0.997	0.000
G71.2 Congenital myopathies	0.002	0.997	0.000
G23 Other degenerative diseases of basal ganglia	0.002	0.997	0.000
R25.2 Cramp and spasm	0.003	0.997	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.002	0.997	0.000
A49.9 Bacterial infection, unspecified	0.002	0.998	0.000
N64 Other disorders of breast	0.002	0.998	0.000
C18.2 Ascending colon	0.002	0.998	0.000
I86.8 Varicose veins of other specified sites	0.002	0.998	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
G36.0 Neuromyelitis optica [Devic]	0.002	0.998	0.000
G62.2 Polyneuropathy due to other toxic agents	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.998	0.002
C49.4 Connective and soft tissue of abdomen	0.000	0.998	0.002
G70 Myasthenia gravis and other myoneural disorders	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
C15.4 Middle third of oesophagus	0.000	0.998	0.002
G71.1 Myotonic disorders	0.002	0.998	0.000
W21.9 Unspecified place	0.000	0.998	0.002
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.998	0.002
H44.4 Hypotony of eye	0.002	0.998	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.002	0.998	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.002	0.998	0.000
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.002
G24.1 Idiopathic familial dystonia	0.002	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
I85.9 Oesophageal varices without bleeding	0.002	0.998	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.002	0.998	0.000
G22 Parkinsonism in diseases classified elsewhere	0.002	0.998	0.000
I86.0 Sublingual varices	0.002	0.998	0.000
N64.1 Fat necrosis of breast	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.000	0.998	0.002
A49.3 Mycoplasma infection, unspecified	0.002	0.998	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.002	0.998	0.000
K83 Other diseases of biliary tract	0.002	0.998	0.000
C46.9 Kaposi's sarcoma, unspecified	0.000	0.998	0.002
C46.8 Kaposi's sarcoma of multiple organs	0.000	0.998	0.002
C46.7 Kaposi's sarcoma of other sites	0.000	0.998	0.002
C46.3 Kaposi's sarcoma of lymph nodes	0.000	0.998	0.002
C46.2 Kaposi's sarcoma of palate	0.000	0.998	0.002
C46.1 Kaposi's sarcoma of soft tissue	0.000	0.998	0.002
C46.0 Kaposi's sarcoma of skin	0.000	0.998	0.002
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.000	0.998	0.002
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.000	0.998	0.002
C47.6 Peripheral nerves of trunk, unspecified	0.000	0.998	0.002
C47.5 Peripheral nerves of pelvis	0.000	0.998	0.002
C47.4 Peripheral nerves of abdomen	0.000	0.998	0.002
C47.3 Peripheral nerves of thorax	0.000	0.998	0.002
C47.2 Peripheral nerves of lower limb, including hip	0.000	0.998	0.002
C47.1 Peripheral nerves of upper limb, including shoulder	0.000	0.998	0.002
C47.0 Peripheral nerves of head, face and neck	0.000	0.998	0.002
G24.0 Drug-induced dystonia	0.002	0.998	0.000
G36.9 Acute disseminated demyelination, unspecified	0.002	0.998	0.000
G36.8 Other specified acute disseminated demyelination	0.002	0.998	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.002	0.998	0.000
R41.1 Anterograde amnesia	0.002	0.998	0.000
G64 Other disorders of peripheral nervous system	0.002	0.998	0.000
E61.1 Iron deficiency	0.002	0.998	0.000
G24.4 Idiopathic orofacial dystonia	0.002	0.998	0.000
G24.2 Idiopathic nonfamilial dystonia	0.002	0.998	0.000
G62.0 Drug-induced polyneuropathy	0.002	0.998	0.000
H44 Disorders of globe	0.002	0.998	0.000
N64.2 Atrophy of breast	0.002	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
G60 Hereditary and idiopathic neuropathy	0.002	0.998	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.002	0.998	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.998	0.002
G24.5 Blepharospasm	0.002	0.998	0.000
G70.8 Other specified myoneural disorders	0.002	0.998	0.000
I86.2 Pelvic varices	0.002	0.998	0.000
M70.2 Olecranon bursitis	0.002	0.998	0.000
N60.3 Fibrosclerosis of breast	0.002	0.998	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.002	0.998	0.000
G24.8 Other dystonia	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.000	0.998	0.002
G70.9 Myoneural disorder, unspecified	0.002	0.998	0.000
G73.7 Myopathy other diseases classified elsewhere	0.002	0.998	0.000
G73.6 Myopathy in metabolic diseases	0.002	0.998	0.000
G73.5 Myopathy in endocrine diseases	0.002	0.998	0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.002	0.998	0.000
G73.2 Other myasthenic syndromes in neoplastic disease	0.002	0.998	0.000
G73.1 Eaton-Lambert syndrome	0.002	0.998	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.002	0.998	0.000
S70 Superficial injury of hip and thigh	0.000	0.998	0.002
G23.9 Degenerative disease of basal ganglia, unspecified	0.002	0.998	0.000
G23.3 Multiple system atrophy, cerebellar type	0.002	0.998	0.000
G23.2 Striatonigral degeneration	0.002	0.998	0.000
G23.0 Hallervorden-Spatz disease	0.002	0.998	0.000
G21 Secondary Parkinsonism	0.002	0.998	0.000
M77.02 Medial epicondylitis (Upper arm)	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
C15.1 Thoracic part of oesophagus	0.000	0.998	0.002
C15.0 Cervical part of oesophagus	0.000	0.998	0.002
N64.0 Fissure and fistula of nipple	0.002	0.998	0.000
E11.3 With ophthalmic complications	0.002	0.998	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.002	0.998	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.002	0.998	0.000
I85 Oesophageal varices	0.002	0.998	0.000
H55-H59 Other disorders of eye and adnexa	0.002	0.998	0.000
A49.1 Streptococcal infection, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations