TreeWAS – Variant ID: rs6548238

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E66.9 Obesity, unspecified	0.000	0.000	1.000
E66 Obesity	0.000	0.000	1.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.001	0.999
E66.8 Other obesity	0.000	0.001	0.999
E11.9 Without complications	0.000	0.002	0.998
E11.4 With neurological complications	0.000	0.007	0.993
E10-E14 Diabetes mellitus	0.000	0.030	0.970
E11.2 With renal complications	0.000	0.032	0.968
E65-E68 Obesity and other hyperalimentation	0.000	0.039	0.961
E11.3 With ophthalmic complications	0.000	0.071	0.929
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.089	0.911
E10 Insulin-dependent diabetes mellitus	0.000	0.130	0.870
E11.5 With peripheral circulatory complications	0.000	0.159	0.841
E65 Localised adiposity	0.000	0.191	0.809
E66.0 Obesity due to excess calories	0.000	0.204	0.796
E11.8 With unspecified complications	0.000	0.206	0.794
E10.9 Without complications	0.000	0.210	0.790
E14 Unspecified diabetes mellitus	0.000	0.250	0.750
E66.1 Drug-induced obesity	0.000	0.283	0.717
E11.7 With multiple complications	0.000	0.283	0.716
E10.4 With neurological complications	0.000	0.299	0.701
E10.2 With renal complications	0.000	0.302	0.698
E12 Malnutrition-related diabetes mellitus	0.000	0.304	0.695
E10.0 With coma	0.000	0.310	0.690
E10.8 With unspecified complications	0.000	0.311	0.689
E67 Other hyperalimentation	0.000	0.311	0.689
E68 Sequelae of hyperalimentation	0.000	0.311	0.689
E14.3 With ophthalmic complications	0.000	0.334	0.666
E11.1 With ketoacidosis	0.000	0.334	0.665
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.351	0.649
E11.6 With other specified complications	0.000	0.358	0.641
E13 Other specified diabetes mellitus	0.000	0.366	0.634
E10.5 With peripheral circulatory complications	0.000	0.376	0.624
E10.7 With multiple complications	0.000	0.376	0.624
E50-E64 Other nutritional deficiencies	0.000	0.401	0.599
E10.6 With other specified complications	0.000	0.406	0.594
E11.0 With coma	0.000	0.411	0.589
E61 Deficiency of other nutrient elements	0.000	0.452	0.548
E14.8 With unspecified complications	0.000	0.461	0.539
E14.7 With multiple complications	0.000	0.462	0.538
E14.6 With other specified complications	0.000	0.462	0.538
E14.5 With peripheral circulatory complications	0.000	0.462	0.538
E14.2 Withrenal complications	0.000	0.462	0.538
E14.1 With ketoacidosis	0.000	0.462	0.538
E14.0 With coma	0.000	0.462	0.538
E10.3 With ophthalmic complications	0.000	0.472	0.528
E61.1 Iron deficiency	0.000	0.487	0.513
E12.9 Without complications	0.000	0.501	0.499
E12.8 With unspecified complications	0.000	0.501	0.499
E12.7 With multiple complications	0.000	0.501	0.499
E12.6 With other specified complications	0.000	0.501	0.499
E12.5 With peripheral circulatory complications	0.000	0.501	0.499
E12.4 With neurological complications	0.000	0.501	0.499
E12.3 With ophthalmic complications	0.000	0.501	0.499
E12.2 With renal complications	0.000	0.501	0.499
E12.1 With ketoacidosis	0.000	0.501	0.499
E12.0 With coma	0.000	0.501	0.499
E67.8 Other specified hyperalimentation	0.000	0.506	0.494
E67.3 Hypervitaminosis D	0.000	0.506	0.494
E67.2 Megavitamin-B6 syndrome	0.000	0.506	0.494
E67.1 Hypercarotenaemia	0.000	0.506	0.494
E67.0 Hypervitaminosis A	0.000	0.506	0.494
E40-E46 Malnutrition	0.000	0.512	0.488
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.513	0.487
E14.4 With neurological complications	0.000	0.538	0.462
E13.8 With unspecified complications	0.000	0.545	0.455
E13.7 With multiple complications	0.000	0.545	0.455
E13.6 With other specified complications	0.000	0.545	0.455
E13.5 With peripheral circulatory complications	0.000	0.545	0.455
E13.4 With neurological complications	0.000	0.545	0.455
E13.3 With ophthalmic complications	0.000	0.545	0.455
E13.2 With renal complications	0.000	0.545	0.455
E13.1 With ketoacidosis	0.000	0.545	0.455
E13.0 With coma	0.000	0.545	0.455
E14.9 Without complications	0.000	0.545	0.455
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.570	0.430
E63 Other nutritional deficiencies	0.000	0.570	0.430
E56 Other vitamin deficiencies	0.000	0.570	0.430
E50 Vitamin A deficiency	0.000	0.570	0.430
E60 Dietary zinc deficiency	0.000	0.570	0.430
E59 Dietary selenium deficiency	0.000	0.570	0.430
E58 Dietary calcium deficiency	0.000	0.570	0.430
E54 Ascorbic acid deficiency	0.000	0.570	0.430
E52 Niacin deficiency [pellagra]	0.000	0.570	0.430
E51 Thiamine deficiency	0.000	0.593	0.407
E13.9 Without complications	0.000	0.606	0.393
E61.9 Deficiency of nutrient element, unspecified	0.000	0.607	0.393
E61.8 Deficiency of other specified nutrient elements	0.000	0.607	0.393
E61.7 Deficiency of multiple nutrient elements	0.000	0.607	0.393
E61.6 Vanadium deficiency	0.000	0.607	0.393
E61.5 Molybdenum deficiency	0.000	0.607	0.393
E61.4 Chromium deficiency	0.000	0.607	0.393
E61.3 Manganese deficiency	0.000	0.607	0.393
E61.0 Copper deficiency	0.000	0.607	0.393
E61.2 Magnesium deficiency	0.000	0.613	0.387
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.650	0.350
E45 Retarded development following protein-energy malnutrition	0.000	0.650	0.350
E43 Unspecified severe protein-energy malnutrition	0.000	0.650	0.350
E42 Marasmic kwashiorkor	0.000	0.650	0.350
E41 Nutritional marasmus	0.000	0.650	0.350
E40 Kwashiorkor	0.000	0.650	0.350
E15 Nondiabetic hypoglycaemic coma	0.000	0.651	0.349
E10.1 With ketoacidosis	0.000	0.673	0.327
E55 Vitamin D deficiency	0.000	0.689	0.311
E50.9 Vitamin A deficiency, unspecified	0.000	0.692	0.308
E50.8 Other manifestations of vitamin A deficiency	0.000	0.692	0.308
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.692	0.308
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.692	0.308
E50.5 Vitamin A deficiency with night blindness	0.000	0.692	0.308
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.692	0.308
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.692	0.308
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.692	0.308
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.692	0.308
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.692	0.308
E56.9 Vitamin deficiency, unspecified	0.000	0.692	0.308
E56.8 Deficiency of other vitamins	0.000	0.692	0.308
E56.1 Deficiency of vitamin K	0.000	0.692	0.308
E56.0 Deficiency of vitamin E	0.000	0.692	0.308
E63.9 Nutritional deficiency, unspecified	0.000	0.692	0.308
E63.8 Other specified nutritional deficiencies	0.000	0.692	0.308
E63.1 Imbalance of constituents of food intake	0.000	0.692	0.308
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.692	0.308
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.692	0.308
E64.8 Sequelae of other nutritional deficiencies	0.000	0.692	0.308
E64.3 Sequelae of rickets	0.000	0.692	0.308
E64.2 Sequelae of vitamin C deficiency	0.000	0.692	0.308
E64.1 Sequelae of vitamin A deficiency	0.000	0.692	0.308
E64.0 Sequelae of protein-energy malnutrition	0.000	0.692	0.308
E51.9 Thiamine deficiency, unspecified	0.000	0.708	0.292
E51.8 Other manifestations of thiamine deficiency	0.000	0.708	0.292
E51.1 Beriberi	0.000	0.708	0.292
E51.2 Wernicke's encephalopathy	0.000	0.730	0.269
E44.1 Mild protein-energy malnutrition	0.000	0.749	0.251
E44.0 Moderate protein-energy malnutrition	0.000	0.749	0.251
I10 Essential (primary) hypertension	0.000	0.762	0.238
E55.0 Rickets, active	0.000	0.777	0.223
E53 Deficiency of other B group vitamins	0.001	0.782	0.218
E46 Unspecified protein-energy malnutrition	0.001	0.815	0.184
E16 Other disorders of pancreatic internal secretion	0.000	0.817	0.182
E53.1 Pyridoxine deficiency	0.001	0.843	0.156
E53.0 Riboflavin deficiency	0.001	0.843	0.156
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.869	0.131
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.869	0.131
E16.4 Abnormal secretion of gastrin	0.000	0.869	0.131
E16.3 Increased secretion of glucagon	0.000	0.869	0.131
E53.9 Vitamin B deficiency, unspecified	0.001	0.870	0.129
E16.1 Other hypoglycaemia	0.000	0.875	0.125
I10-I15 Hypertensive diseases	0.000	0.885	0.115
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.887	0.113
E55.9 Vitamin D deficiency, unspecified	0.000	0.895	0.104
I12 Hypertensive renal disease	0.000	0.908	0.092
I15 Secondary hypertension	0.000	0.911	0.089
I13 Hypertensive heart and renal disease	0.000	0.917	0.083
G56.0 Carpal tunnel syndrome	0.000	0.919	0.081
I12.9 Hypertensive renal disease without renal failure	0.000	0.922	0.078
I15.1 Hypertension secondary to other renal disorders	0.000	0.927	0.072
I11 Hypertensive heart disease	0.000	0.929	0.070
I84.6 Residual haemorrhoidal skin tags	0.000	0.932	0.068
I15.8 Other secondary hypertension	0.000	0.936	0.064
I15.2 Hypertension secondary to endocrine disorders	0.000	0.936	0.064
I15.0 Renovascular hypertension	0.000	0.936	0.064
I15.9 Seconday hypertension, unspecified	0.000	0.939	0.061
I12.0 Hypertensive renal disease with renal failure	0.000	0.939	0.061
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.940	0.060
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.940	0.060
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.940	0.060
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.940	0.060
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.949	0.051
E00-E07 Disorders of thyroid gland	0.000	0.955	0.044
Z86.4 Personal history of psychoactive substance abuse	0.000	0.958	0.042
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.962	0.038
E16.2 Hypoglycaemia, unspecified	0.000	0.962	0.037
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.968	0.032
E00 Congenital iodine-deficiency syndrome	0.000	0.968	0.032
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.968	0.032
E07 Other disorders of thyroid	0.000	0.970	0.030
E53.8 Deficiency of other specified B group vitamins	0.001	0.971	0.028
E07.9 Disorder of thyroid, unspecified	0.000	0.976	0.024
G56 Mononeuropathies of upper limb	0.000	0.977	0.023
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.977	0.023
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.977	0.023
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.977	0.023
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.977	0.023
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.977	0.023
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.977	0.023
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.977	0.023
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.977	0.023
E20-E35 Disorders of other endocrine glands	0.004	0.978	0.018
E07.1 Dyshormogenetic goitre	0.000	0.978	0.022
E07.0 Hypersecretion of calcitonin	0.000	0.978	0.022
J22 Unspecified acute lower respiratory infection	0.000	0.979	0.021
K76.8 Other specified diseases of liver	0.020	0.980	0.000
E06 Thyroiditis	0.000	0.980	0.020
G56.8 Other mononeuropathies of upper limb	0.000	0.982	0.018
G56.3 Lesion of radial nerve	0.000	0.982	0.017
G56.1 Other lesions of median nerve	0.000	0.983	0.017
E07.8 Other specified disorders of thyroid	0.000	0.983	0.016
G59.0 Diabetic mononeuropathy	0.000	0.984	0.016
E34 Other endocrine disorders	0.002	0.984	0.014
G56.9 Mononeuropathy of upper limb, unspecified	0.000	0.984	0.016
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.984	0.013
E32 Diseases of thymus	0.003	0.984	0.013
E31 Polyglandular dysfunction	0.003	0.984	0.013
E30 Disorders of puberty, not elsewhere classified	0.003	0.984	0.013
G56.4 Causalgia	0.000	0.984	0.016
E20 Hypoparathyroidism	0.003	0.985	0.012
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.985	0.015
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.985	0.015
O48 Prolonged pregnancy	0.015	0.985	0.000
E26 Hyperaldosteronism	0.003	0.985	0.012
E25 Adrenogenital disorders	0.004	0.985	0.011
G47.3 Sleep apnoea	0.000	0.985	0.015
G40-G47 Episodic and paroxysmal disorders	0.000	0.985	0.015
E06.5 Other chronic thyroiditis	0.000	0.985	0.014
E06.4 Drug-induced thyroiditis	0.000	0.985	0.014
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.985	0.014
E06.1 Subacute thyroiditis	0.000	0.985	0.014
E06.0 Acute thyroiditis	0.000	0.985	0.014
I85.9 Oesophageal varices without bleeding	0.000	0.986	0.014
E29 Testicular dysfunction	0.003	0.986	0.011
G43.1 Migraine with aura [classical migraine]	0.000	0.986	0.014
I85 Oesophageal varices	0.000	0.986	0.014
I84.4 External haemorrhoids with other complications	0.000	0.986	0.014
G43 Migraine	0.000	0.986	0.014
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.986	0.014
E28 Ovarian dysfunction	0.003	0.986	0.011
G47 Sleep disorders	0.000	0.986	0.014
I84 Haemorrhoids	0.000	0.986	0.014
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.987	0.013
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.987	0.013
I89.0 Lymphoedema, not elsewhere classified	0.000	0.987	0.013
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.987	0.013
E34.9 Endocrine disorder, unspecified	0.001	0.987	0.012
I80 Phlebitis and thrombophlebitis	0.000	0.987	0.013
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.987	0.013
G44 Other headache syndromes	0.000	0.987	0.013
E24 Cushing's syndrome	0.004	0.987	0.009
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.988	0.012
I82 Other venous embolism and thrombosis	0.000	0.988	0.012
E22 Hyperfunction of pituitary gland	0.003	0.988	0.009
S83.2 Tear of meniscus, current	0.000	0.988	0.012
G59 Mononeuropathy in diseases classified elsewhere	0.000	0.988	0.012
G44.2 Tension-type headache	0.000	0.988	0.012
E34.5 Androgen resistance syndrome	0.002	0.988	0.010
E34.4 Constitutional tall stature	0.002	0.988	0.010
E34.3 Short stature, not elsewhere classified	0.002	0.988	0.010
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.988	0.010
E34.1 Other hypersecretion of intestinal hormones	0.002	0.988	0.010
E34.0 Carcinoid syndrome	0.002	0.988	0.010
E30.9 Disorder of puberty, unspecified	0.002	0.988	0.009
E30.8 Other disorders of puberty	0.002	0.988	0.009
E30.1 Precocious puberty	0.002	0.988	0.009
E30.0 Delayed puberty	0.002	0.988	0.009
E31.9 Polyglandular dysfunction, unspecified	0.002	0.988	0.009
E31.8 Other polyglandular dysfunction	0.002	0.988	0.009
E31.1 Polyglandular hyperfunction	0.002	0.988	0.009
E31.0 Autoimmune polyglandular failure	0.002	0.988	0.009
E32.9 Disease of thymus, unspecified	0.002	0.988	0.009
E32.8 Other diseases of thymus	0.002	0.988	0.009
E32.1 Abscess of thymus	0.002	0.988	0.009
E32.0 Persistent hyperplasia of thymus	0.002	0.988	0.009
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.988	0.009
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.988	0.009
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.988	0.009
G45.3 Amaurosis fugax	0.000	0.988	0.012
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.988	0.012
G43.8 Other migraine	0.000	0.988	0.012
E20.8 Other hypoparathyroidism	0.002	0.989	0.009
E20.1 Pseudohypoparathyroidism	0.002	0.989	0.009
E20.0 Idiopathic hypoparathyroidism	0.002	0.989	0.009
G41 Status epilepticus	0.000	0.989	0.011
E23 Hypofunction and other disorders of pituitary gland	0.005	0.989	0.006
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.989	0.011
I82.8 Embolism and thrombosis of other specified veins	0.000	0.989	0.011
E34.8 Other specified endocrine disorders	0.002	0.989	0.009
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.989	0.011
G46 Vascular syndromes of brain in cerebrovascular diseases	0.000	0.989	0.011
G45.0 Vertebro-basilar artery syndrome	0.000	0.989	0.011
E26.9 Hyperaldosteronism, unspecified	0.003	0.989	0.008
E26.8 Other hyperaldosteronism	0.003	0.989	0.008
E26.1 Secondary hyperaldosteronism	0.003	0.989	0.008
E25.9 Adrenogenital disorder, unspecified	0.003	0.989	0.008
E25.8 Other adrenogenital disorders	0.003	0.989	0.008
H54.7 Unspecified visual loss	0.000	0.989	0.011
E03 Other hypothyroidism	0.000	0.989	0.011
E06.3 Autoimmune thyroiditis	0.000	0.989	0.010
E20.9 Hypoparathyroidism, unspecified	0.002	0.989	0.008
I81 Portal vein thrombosis	0.000	0.989	0.010
E29.9 Testicular dysfunction, unspecified	0.002	0.989	0.008
E29.8 Other testicular dysfunction	0.002	0.989	0.008
E29.0 Testicular hyperfunction	0.002	0.989	0.008
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.990	0.010
G43.0 Migraine without aura [common migraine]	0.000	0.990	0.010
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.990	0.010
I85.0 Oesophageal varices with bleeding	0.000	0.990	0.010
I84.0 Internal thrombosed haemorrhoids	0.000	0.990	0.010
E70-E90 Metabolic disorders	0.000	0.990	0.010
G43.3 Complicated migraine	0.000	0.990	0.010
G43.2 Status migrainosus	0.000	0.990	0.010
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.990	0.010
E28.9 Ovarian dysfunction, unspecified	0.002	0.990	0.008
E28.8 Other ovarian dysfunction	0.002	0.990	0.008
E28.1 Androgen excess	0.002	0.990	0.008
E28.0 Oestrogen excess	0.002	0.990	0.008
G47.2 Disorders of the sleep-wake schedule	0.000	0.990	0.010
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.990	0.010
I89.1 Lymphangitis	0.000	0.990	0.010
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.990	0.010
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.990	0.010
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.990	0.010
E06.9 Thyroiditis, unspecified	0.001	0.990	0.009
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.990	0.006
G47.4 Narcolepsy and cataplexy	0.000	0.990	0.010
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.990	0.006
E26.0 Primary hyperaldosteronism	0.003	0.990	0.007
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.990	0.010
G44.0 Cluster headache syndrome	0.000	0.990	0.010
I86 Varicose veins of other sites	0.000	0.990	0.010
G44.3 Chronic posttraumatic headache	0.000	0.990	0.009
G44.1 Vascular headache, not elsewhere classified	0.000	0.990	0.009
E24.8 Other Cushing's syndrome	0.003	0.991	0.007
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.991	0.007
E24.3 Ectopic ACTH syndrome	0.003	0.991	0.007
E24.1 Nelson's syndrome	0.003	0.991	0.007
G45.4 Transient global amnesia	0.000	0.991	0.009
I84.1 Internal haemorrhoids with other complications	0.000	0.991	0.009
I50.0 Congestive heart failure	0.000	0.991	0.009
E28.2 Polycystic ovarian syndrome	0.002	0.991	0.008
E24.0 Pituitary-dependent Cushing's disease	0.003	0.991	0.006
I82.3 Embolism and thrombosis of renal vein	0.000	0.991	0.009
I82.1 Thrombophlebitis migrans	0.000	0.991	0.009
I82.0 Budd-Chiari syndrome	0.000	0.991	0.009
G47.8 Other sleep disorders	0.000	0.991	0.009
Z50.1 Other physical therapy	0.000	0.991	0.009
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.991	0.007
E22.8 Other hyperfunction of pituitary gland	0.002	0.991	0.007
G59.8 Other mononeuropathies in diseases classified elsewhere	0.000	0.991	0.009
G50-G59 Nerve, nerve root and plexus disorders	0.000	0.991	0.009
N99.0 Postprocedural renal failure	0.000	0.991	0.009
G41.9 Status epilepticus, unspecified	0.000	0.991	0.009
N99.5 Malfunction of external stoma of urinary tract	0.000	0.991	0.009
E05.8 Other thyrotoxicosis	0.000	0.991	0.008
E05.5 Thyroid crisis or storm	0.000	0.991	0.008
E05.4 Thyrotoxicosis factitia	0.000	0.991	0.008
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.991	0.008
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.991	0.008
E29.1 Testicular hypofunction	0.002	0.991	0.007
G41.0 Grand mal status epilepticus	0.000	0.991	0.008
G46.7 Other lacunar syndromes	0.000	0.992	0.008
E85 Amyloidosis	0.000	0.992	0.008
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.992	0.008
E24.9 Cushing's syndrome, unspecified	0.003	0.992	0.006
G41.8 Other status epilepticus	0.000	0.992	0.008
G41.2 Complex partial status epilepticus	0.000	0.992	0.008
G41.1 Petit mal status epilepticus	0.000	0.992	0.008
E24.2 Drug-induced Cushing's syndrome	0.003	0.992	0.005
E28.3 Primary ovarian failure	0.003	0.992	0.006
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.992	0.008
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.004	0.992	0.004
E23.1 Drug-induced hypopituitarism	0.004	0.992	0.004
N99.2 Postprocedural adhesions of vagina	0.000	0.992	0.008
I86.8 Varicose veins of other specified sites	0.000	0.992	0.008
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.000	0.992	0.008
G46.6 Pure sensory lacunar syndrome	0.000	0.992	0.008
G46.5 Pure motor lacunar syndrome	0.000	0.992	0.008
G46.4 Cerebellar stroke syndrome	0.000	0.992	0.008
G46.3 Brain stem stroke syndrome	0.000	0.992	0.008
G46.2 Posterior cerebral artery syndrome	0.000	0.992	0.008
G46.1 Anterior cerebral artery syndrome	0.000	0.992	0.008
G46.0 Middle cerebral artery syndrome	0.000	0.992	0.008
E27 Other disorders of adrenal gland	0.004	0.992	0.005
E03.5 Myxoedema coma	0.000	0.992	0.008
E03.4 Atrophy of thyroid (acquired)	0.000	0.992	0.008
E03.3 Postinfectious hypothyroidism	0.000	0.992	0.008
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.992	0.008
E23.6 Other disorders of pituitary gland	0.003	0.992	0.005
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.992	0.006
E23.7 Disorder of pituitary gland, unspecified	0.004	0.992	0.004
E22.0 Acromegaly and pituitary gigantism	0.002	0.992	0.006
I82.2 Embolism and thrombosis of vena cava	0.000	0.992	0.008
N99.1 Postprocedural urethral stricture	0.000	0.992	0.008
I88 Nonspecific lymphadenitis	0.001	0.992	0.007
G47.9 Sleep disorder, unspecified	0.000	0.992	0.008
G40 Epilepsy	0.000	0.992	0.008
I87 Other disorders of veins	0.000	0.992	0.008
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.992	0.008
E22.1 Hyperprolactinaemia	0.003	0.992	0.005
E84 Cystic fibrosis	0.000	0.992	0.007
E79 Disorders of purine and pyrimidine metabolism	0.000	0.992	0.007
E77 Disorders of glycoprotein metabolism	0.000	0.992	0.007
E76 Disorders of glycosaminoglycan metabolism	0.000	0.992	0.007
E72 Other disorders of amino-acid metabolism	0.000	0.992	0.007
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.992	0.007
E70 Disorders of aromatic amino-acid metabolism	0.000	0.992	0.007
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.992	0.007
H54 Blindness and low vision	0.000	0.992	0.008
E73 Lactose intolerance	0.000	0.993	0.007
E23.2 Diabetes insipidus	0.005	0.993	0.002
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.993	0.007
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.993	0.007
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.993	0.007
J20-J22 Other acute lower respiratory infections	0.000	0.993	0.007
N80.9 Endometriosis, unspecified	0.007	0.993	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.993	0.007
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.993	0.007
E21.4 Other specified disorders of parathyroid gland	0.003	0.993	0.005
E21.2 Other hyperparathyroidism	0.003	0.993	0.005
I86.2 Pelvic varices	0.000	0.993	0.007
H54.9 Unspecified visual impairment (binocular)	0.000	0.993	0.007
E03.1 Congenital hypothyroidism without goitre	0.000	0.993	0.007
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.993	0.007
I86.3 Vulval varices	0.000	0.993	0.007
I86.0 Sublingual varices	0.000	0.993	0.007
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.993	0.007
E23.0 Hypopituitarism	0.006	0.993	0.001
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.993	0.007
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.993	0.005
I86.4 Gastric varices	0.000	0.993	0.007
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.993	0.004
E85.4 Organ-limited amyloidosis	0.000	0.993	0.007
I84.3 External thrombosed haemorrhoids	0.000	0.993	0.007
G44.8 Other specified headache syndromes	0.000	0.993	0.006
E74 Other disorders of carbohydrate metabolism	0.000	0.993	0.007
E85.9 Amyloidosis, unspecified	0.000	0.993	0.007
E03.8 Other specified hypothyroidism	0.000	0.993	0.006
G35 Multiple sclerosis	0.006	0.993	0.000
G52 Disorders of other cranial nerves	0.000	0.994	0.006
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.994	0.006
E85.8 Other amyloidosis	0.000	0.994	0.006
E85.3 Secondary systemic amyloidosis	0.000	0.994	0.006
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.994	0.006
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.994	0.006
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.994	0.006
G56.2 Lesion of ulnar nerve	0.000	0.994	0.006
Z86 Personal history of certain other diseases	0.000	0.994	0.006
Chapter IX Diseases of the circulatory system	0.000	0.994	0.006
G40.9 Epilepsy, unspecified	0.000	0.994	0.006
E27.5 Adrenomedullary hyperfunction	0.003	0.994	0.003
E27.0 Other adrenocortical overactivity	0.003	0.994	0.003
G40.8 Other epilepsy	0.000	0.994	0.006
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.994	0.006
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.994	0.006
M43.1 Spondylolisthesis	0.000	0.994	0.006
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.994	0.003
I87.1 Compression of vein	0.000	0.994	0.006
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.994	0.006
H54.0 Blindness, both eyes	0.000	0.994	0.006
I88.8 Other nonspecific lymphadenitis	0.001	0.994	0.005
I88.1 Chronic lymphadenitis, except mesenteric	0.001	0.994	0.005
I88.0 Nonspecific mesenteric lymphadenitis	0.001	0.994	0.005
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.994	0.006
E27.2 Addisonian crisis	0.002	0.994	0.003
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.994	0.006
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.994	0.006
E78.8 Other disorders of lipoprotein metabolism	0.000	0.994	0.006
I87.9 Disorder of vein, unspecified	0.000	0.994	0.006
I87.0 Postphlebitic syndrome	0.000	0.994	0.006
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.994	0.006
E87.5 Hyperkalaemia	0.000	0.994	0.006
G40.5 Special epileptic syndromes	0.000	0.994	0.006
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.994	0.006
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.994	0.006
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.994	0.006
E70.3 Albinism	0.000	0.994	0.006
E70.2 Disorders of tyrosine metabolism	0.000	0.994	0.006
E70.1 Other hyperphenylalaninaemias	0.000	0.994	0.006
E70.0 Classical phenylketonuria	0.000	0.994	0.006
E71.3 Disorders of fatty-acid metabolism	0.000	0.994	0.006
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.994	0.006
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.994	0.006
E71.0 Maple-syrup-urine disease	0.000	0.994	0.006
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.994	0.006
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.994	0.006
E72.5 Disorders of glycine metabolism	0.000	0.994	0.006
E72.4 Disorders of ornithine metabolism	0.000	0.994	0.006
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.994	0.006
E72.2 Disorders of urea cycle metabolism	0.000	0.994	0.006
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.994	0.006
E72.0 Disorders of amino-acid transport	0.000	0.994	0.006
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.994	0.006
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.994	0.006
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.994	0.006
E76.2 Other mucopolysaccharidoses	0.000	0.994	0.006
E76.1 Mucopolysaccharidosis, type II	0.000	0.994	0.006
E76.0 Mucopolysaccharidosis, type I	0.000	0.994	0.006
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.994	0.006
E77.8 Other disorders of glycoprotein metabolism	0.000	0.994	0.006
E77.1 Defects in glycoprotein degradation	0.000	0.994	0.006
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.994	0.006
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.994	0.006
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.994	0.006
E79.1 Lesch-Nyhan syndrome	0.000	0.994	0.006
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.994	0.006
E84.9 Cystic fibrosis, unspecified	0.000	0.994	0.006
E84.8 Cystic fibrosis with other manifestations	0.000	0.994	0.006
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.994	0.006
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.994	0.006
G53 Cranial nerve disorders in diseases classified elsewhere	0.000	0.994	0.006
H54.6 Unqualified visual loss, one eye	0.000	0.994	0.006
H54.5 Low vision, one eye	0.000	0.994	0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations