TreeWAS – Variant ID: rs6555855

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.60 Fracture of lateral malleolus (closed)	0.226	0.774	0.000
S82.6 Fracture of lateral malleolus	0.165	0.835	0.000
S82.61 Fracture of lateral malleolus (open)	0.128	0.872	0.000
S82 Fracture of lower leg, including ankle	0.110	0.890	0.000
S82.1 Fracture of upper end of tibia	0.102	0.898	0.000
S82.4 Fracture of fibula alone	0.100	0.900	0.000
S82.10 Fracture of upper end of tibia (closed)	0.095	0.905	0.000
S82.40 Fracture of fibula alone (closed)	0.094	0.906	0.000
S82.7 Multiple fractures of lower leg	0.090	0.910	0.000
S82.11 Fracture of upper end of tibia (open)	0.081	0.919	0.000
S82.70 Multiple fractures of lower leg (closed)	0.077	0.923	0.000
S82.9 Fracture of lower leg, part unspecified	0.076	0.923	0.000
S82.2 Fracture of shaft of tibia	0.074	0.926	0.000
S82.41 Fracture of fibula alone (open)	0.072	0.928	0.000
S82.71 Multiple fractures of lower leg (open)	0.065	0.935	0.000
S82.0 Fracture of patella	0.064	0.936	0.000
S82.21 Fracture of shaft of tibia (open)	0.059	0.941	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.059	0.941	0.000
S82.5 Fracture of medial malleolus	0.058	0.942	0.000
S82.3 Fracture of lower end of tibia	0.054	0.946	0.000
S82.8 Fractures of other parts of lower leg	0.050	0.950	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.048	0.952	0.000
S82.00 Fracture of patella (closed)	0.041	0.959	0.000
S82.51 Fracture of medial malleolus (open)	0.040	0.960	0.000
S82.20 Fracture of shaft of tibia (closed)	0.039	0.961	0.000
S82.01 Fracture of patella (open)	0.038	0.962	0.000
S82.86 Maisonneuve's fracture	0.036	0.964	0.000
S80-S89 Injuries to the knee and lower leg	0.034	0.966	0.000
S82.31 Fracture of lower end of tibia (open)	0.032	0.967	0.000
S82.81 Fractures of other parts of lower leg (open)	0.032	0.968	0.000
S86 Injury of muscle and tendon at lower leg level	0.031	0.969	0.000
C67.2 Lateral wall of bladder	0.028	0.972	0.000
S87 Crushing injury of lower leg	0.027	0.973	0.000
S82.30 Fracture of lower end of tibia (closed)	0.027	0.973	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.026	0.974	0.000
S85 Injury of blood vessels at lower leg level	0.026	0.974	0.000
S84 Injury of nerves at lower leg level	0.026	0.974	0.000
S82.50 Fracture of medial malleolus (closed)	0.025	0.975	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.025	0.975	0.000
S88 Traumatic amputation of lower leg	0.025	0.975	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.976	0.024
C15.9 Oesophagus, unspecified	0.000	0.976	0.024
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.024	0.976	0.000
C67 Malignant neoplasm of bladder	0.024	0.976	0.000
C67.9 Bladder, unspecified	0.023	0.977	0.000
C15.5 Lower third of oesophagus	0.000	0.977	0.023
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.977	0.023
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.022	0.977	0.000
S86.0 Injury of Achilles tendon	0.022	0.978	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.022	0.978	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.022	0.978	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.021	0.979	0.000
S81 Open wound of lower leg	0.021	0.979	0.000
C15.3 Upper third of oesophagus	0.000	0.980	0.020
C67.6 Ureteric orifice	0.020	0.980	0.000
S87.0 Crushing injury of knee	0.020	0.980	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.020	0.980	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.019	0.981	0.000
C67.3 Anterior wall of bladder	0.019	0.981	0.000
C15.1 Thoracic part of oesophagus	0.000	0.981	0.019
S89 Other and unspecified injuries of lower leg	0.019	0.981	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.019	0.981	0.000
S85.8 Injury of other blood vessels at lower leg level	0.019	0.981	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.019	0.981	0.000
S85.5 Injury of popliteal vein	0.019	0.981	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.019	0.981	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.019	0.981	0.000
S85.2 Injury of peroneal artery	0.019	0.981	0.000
S85.0 Injury of popliteal artery	0.019	0.981	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.018	0.981	0.000
S84.8 Injury of other nerves at lower leg level	0.018	0.981	0.000
S84.7 Injury of multiple nerves at lower leg level	0.018	0.981	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.018	0.981	0.000
S84.0 Injury of tibial nerve at lower leg level	0.018	0.981	0.000
S80 Superficial injury of lower leg	0.018	0.982	0.000
C15.4 Middle third of oesophagus	0.000	0.982	0.018
S88.9 Traumatic amputation of lower leg, level unspecified	0.018	0.982	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.018	0.982	0.000
S88.0 Traumatic amputation at knee level	0.018	0.982	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.018	0.982	0.000
C15.8 Overlapping lesion of oesophagus	0.000	0.982	0.017
C15.2 Abdominal part of oesophagus	0.000	0.982	0.017
S81.0 Open wound of knee	0.017	0.983	0.000
C15-C26 Malignant neoplasms of digestive organs	0.000	0.983	0.017
C67.7 Urachus	0.017	0.983	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.017	0.983	0.000
C67.0 Trigone of bladder	0.017	0.983	0.000
C15.0 Cervical part of oesophagus	0.000	0.983	0.017
C67.4 Posterior wall of bladder	0.017	0.983	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.017	0.983	0.000
S86.00 Unspecified injury of Achilles tendon	0.016	0.984	0.000
C67.8 Overlapping lesion of bladder	0.016	0.984	0.000
C67.1 Dome of bladder	0.015	0.985	0.000
S81.7 Multiple open wounds of lower leg	0.015	0.985	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.985	0.015
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.985	0.015
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.986	0.014
C20 Malignant neoplasm of rectum	0.000	0.986	0.014
C67.5 Bladder neck	0.014	0.986	0.000
S89.7 Multiple injuries of lower leg	0.014	0.986	0.000
S89.1 Other specified injuries of lower leg	0.014	0.986	0.000
S89.0 Multiple injuries of lower leg	0.014	0.986	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.014	0.986	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.014	0.986	0.000
S83.7 Injury to multiple structures of knee	0.013	0.986	0.000
S81.8 Open wound of other parts of lower leg	0.014	0.986	0.000
C23 Malignant neoplasm of gallbladder	0.000	0.987	0.013
S83.0 Dislocation of patella	0.013	0.987	0.000
D23.3 Skin of other and unspecified parts of face	0.000	0.987	0.013
S80.7 Multiple superficial injuries of lower leg	0.013	0.987	0.000
C26.9 Ill-defined sites within the digestive system	0.000	0.987	0.013
S83.1 Dislocation of knee	0.012	0.988	0.000
S89.9 Unspecified injury of lower leg	0.012	0.988	0.000
S81.9 Open wound of lower leg, part unspecified	0.012	0.988	0.000
S83.3 Tear of articular cartilage of knee, current	0.012	0.988	0.000
S80.0 Contusion of knee	0.012	0.988	0.000
C17 Malignant neoplasm of small intestine	0.000	0.988	0.012
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.989	0.011
C22.0 Liver cell carcinoma	0.000	0.989	0.011
C22.1 Intrahepatic bile duct carcinoma	0.000	0.989	0.011
C26.8 Overlapping lesion of digestive system	0.000	0.989	0.011
C26.1 Spleen	0.000	0.989	0.011
C22.9 Liver, unspecified	0.000	0.990	0.010
C22.7 Other specified carcinomas of liver	0.000	0.990	0.010
C22.4 Other sarcomas of liver	0.000	0.990	0.010
C22.3 Angiosarcoma of liver	0.000	0.990	0.010
C22.2 Hepatoblastoma	0.000	0.990	0.010
C25 Malignant neoplasm of pancreas	0.000	0.990	0.010
S83.2 Tear of meniscus, current	0.010	0.990	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.990	0.010
S89.8 Other specified injuries of lower leg	0.010	0.990	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.010	0.990	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.990	0.010
C17.1 Jejunum	0.000	0.991	0.009
C17.0 Duodenum	0.000	0.991	0.009
C21 Malignant neoplasm of anus and anal canal	0.000	0.991	0.009
C17.8 Overlapping lesion of small intestine	0.000	0.991	0.008
C17.3 Meckel's diverticulum	0.000	0.991	0.008
C17.9 Small intestine, unspecified	0.000	0.991	0.008
C25.3 Pancreatic duct	0.000	0.991	0.008
C24.1 Ampulla of Vater	0.000	0.991	0.008
C24.8 Overlapping lesion of biliary tract	0.000	0.992	0.008
M25.84 Other specified joint disorders (Hand)	0.000	0.992	0.008
S80.9 Superficial injury of lower leg, unspecified	0.008	0.992	0.000
C25.0 Head of pancreas	0.000	0.992	0.008
S27.0 Traumatic pneumothorax	0.000	0.992	0.008
C24.0 Extrahepatic bile duct	0.000	0.992	0.008
C25.1 Body of pancreas	0.000	0.992	0.008
C25.4 Endocrine pancreas	0.000	0.992	0.007
C25.8 Overlapping lesion of pancreas	0.000	0.992	0.007
S80.8 Other superficial injuries of lower leg	0.007	0.993	0.000
C24.9 Biliary tract, unspecified	0.000	0.993	0.007
M25.8 Other specified joint disorders	0.000	0.993	0.007
C25.7 Other parts of pancreas	0.000	0.993	0.007
L73.9 Follicular disorder, unspecified	0.000	0.993	0.007
C25.2 Tail of pancreas	0.000	0.993	0.007
C21.2 Cloacogenic zone	0.000	0.993	0.006
C17.2 Ileum	0.000	0.994	0.006
N21.0 Calculus in bladder	0.006	0.994	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.994	0.006
C16 Malignant neoplasm of stomach	0.000	0.994	0.006
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.000	0.994	0.006
C16.0 Cardia	0.000	0.994	0.006
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.994	0.006
C25.9 Pancreas, unspecified	0.000	0.994	0.006
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.994	0.005
C21.0 Anus, unspecified	0.000	0.995	0.005
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.995	0.005
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.995	0.005
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.995	0.005
M25.82 Other specified joint disorders (Upper arm)	0.000	0.995	0.005
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.995	0.005
M25.83 Other specified joint disorders (Forearm)	0.000	0.995	0.005
C16.8 Overlapping lesion of stomach	0.000	0.995	0.004
C21.1 Anal canal	0.000	0.995	0.004
K75.9 Inflammatory liver disease, unspecified	0.005	0.995	0.000
M25.88 Other specified joint disorders (Other)	0.000	0.995	0.004
E23.0 Hypopituitarism	0.000	0.996	0.004
N21 Calculus of lower urinary tract	0.004	0.996	0.000
C16.2 Body of stomach	0.000	0.996	0.004
N21.1 Calculus in urethra	0.004	0.996	0.000
C16.5 Lesser curvature of stomach, unspecified	0.000	0.996	0.004
C16.1 Fundus of stomach	0.000	0.996	0.004
C16.6 Greater curvature of stomach, unspecified	0.000	0.996	0.004
L73 Other follicular disorders	0.000	0.996	0.004
E27 Other disorders of adrenal gland	0.000	0.996	0.004
E23 Hypofunction and other disorders of pituitary gland	0.000	0.996	0.004
C16.4 Pylorus	0.000	0.996	0.004
L81.4 Other melanin hyperpigmentation	0.004	0.996	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.996	0.004
E27.2 Addisonian crisis	0.000	0.996	0.004
I31.9 Disease of pericardium, unspecified	0.000	0.996	0.004
C16.3 Pyloric antrum	0.000	0.996	0.003
E23.2 Diabetes insipidus	0.000	0.996	0.004
C80.9 Malignant neoplasm, unspecified	0.004	0.996	0.000
M79.2 Neuralgia and neuritis, unspecified	0.000	0.996	0.004
N21.8 Other lower urinary tract calculus	0.004	0.996	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.996	0.004
M25.86 Other specified joint disorders (Lower leg)	0.000	0.996	0.004
C64-C68 Malignant neoplasms of urinary tract	0.004	0.996	0.000
E34 Other endocrine disorders	0.000	0.996	0.004
D47.2 Monoclonal gammopathy	0.000	0.996	0.004
G96.0 Cerebrospinal fluid leak	0.000	0.996	0.004
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.996	0.003
L73.2 Hidradenitis suppurativa	0.000	0.996	0.003
M25.47 Effusion of joint (Ankle and foot)	0.003	0.997	0.000
N36.8 Other specified disorders of urethra	0.003	0.997	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.003	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.003	0.997	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.003
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.003
K14.8 Other diseases of tongue	0.000	0.997	0.003
E24 Cushing's syndrome	0.000	0.997	0.003
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.997	0.003
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.997	0.003
E27.9 Disorder of adrenal gland, unspecified	0.000	0.997	0.003
L73.1 Pseudofolliculitis barbae	0.000	0.997	0.003
L73.8 Other specified follicular disorders	0.000	0.997	0.003
E20 Hypoparathyroidism	0.000	0.997	0.003
D47.1 Chronic myeloproliferative disease	0.000	0.997	0.003
L73.0 Acne keloid	0.000	0.997	0.003
C68 Malignant neoplasm of other and unspecified urinary organs	0.003	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.997	0.003
E27.0 Other adrenocortical overactivity	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
E20.9 Hypoparathyroidism, unspecified	0.000	0.997	0.003
E23.1 Drug-induced hypopituitarism	0.000	0.997	0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
E29 Testicular dysfunction	0.000	0.997	0.003
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.997	0.003
E34.3 Short stature, not elsewhere classified	0.000	0.997	0.003
L81.9 Disorder of pigmentation, unspecified	0.003	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.997	0.003
N21.9 Calculus of lower urinary tract, unspecified	0.003	0.997	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.000	0.997	0.003
S27 Injury of other and unspecified intrathoracic organs	0.000	0.997	0.003
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.997	0.003
E34.0 Carcinoid syndrome	0.000	0.997	0.003
E32 Diseases of thymus	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.000	0.997	0.003
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.000	0.997	0.003
C68.0 Urethra	0.003	0.997	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.000	0.997	0.003
C16.9 Stomach, unspecified	0.000	0.997	0.003
Q82.5 Congenital nonneoplastic naevus	0.000	0.997	0.003
L81 Other disorders of pigmentation	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.997	0.003
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.000	0.997	0.003
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.000	0.997	0.003
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.000	0.997	0.003
D47.4 Osteomyelofibrosis	0.000	0.997	0.003
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.997	0.003
E30 Disorders of puberty, not elsewhere classified	0.000	0.997	0.003
A87.9 Viral meningitis, unspecified	0.000	0.997	0.003
E34.5 Androgen resistance syndrome	0.000	0.997	0.003
E34.4 Constitutional tall stature	0.000	0.997	0.003
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.997	0.003
E34.1 Other hypersecretion of intestinal hormones	0.000	0.997	0.003
E24.9 Cushing's syndrome, unspecified	0.000	0.997	0.003
M25.76 Osteophyte (Lower leg)	0.000	0.997	0.003
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.997	0.003
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.003	0.997	0.000
C66 Malignant neoplasm of ureter	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.000	0.997	0.003
G96 Other disorders of central nervous system	0.000	0.997	0.003
E25 Adrenogenital disorders	0.000	0.997	0.003
G95.8 Other specified diseases of spinal cord	0.000	0.997	0.003
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.997	0.003
E24.3 Ectopic ACTH syndrome	0.000	0.997	0.003
E24.1 Nelson's syndrome	0.000	0.997	0.003
E24.8 Other Cushing's syndrome	0.000	0.997	0.003
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
E32.9 Disease of thymus, unspecified	0.000	0.997	0.003
I50.9 Heart failure, unspecified	0.003	0.997	0.000
E21.2 Other hyperparathyroidism	0.000	0.997	0.003
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.997	0.003
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.000	0.997	0.003
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.000	0.997	0.002
M50.3 Other cervical disk degeneration	0.000	0.997	0.003
E20.0 Idiopathic hypoparathyroidism	0.000	0.997	0.002
E34.8 Other specified endocrine disorders	0.000	0.997	0.002
C68.8 Overlapping lesion of urinary organs	0.002	0.997	0.000
C68.1 Paraurethral glands	0.002	0.997	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.997	0.002
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.002
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.997	0.002
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
E29.8 Other testicular dysfunction	0.000	0.997	0.002
E29.0 Testicular hyperfunction	0.000	0.997	0.002
L81.7 Pigmented purpuric dermatosis	0.002	0.997	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.997	0.002
G03.9 Meningitis, unspecified	0.000	0.997	0.002
S27.9 Injury of unspecified intrathoracic organ	0.000	0.997	0.002
S27.7 Multiple injuries of intrathoracic organs	0.000	0.997	0.002
S27.6 Injury of pleura	0.000	0.997	0.002
S27.5 Injury of thoracic trachea	0.000	0.997	0.002
S27.4 Injury of bronchus	0.000	0.997	0.002
L81.2 Freckles	0.002	0.997	0.000
S27.1 Traumatic haemothorax	0.000	0.997	0.002
B17.1 Acute hepatitis C	0.000	0.998	0.002
C68.9 Urinary organ, unspecified	0.002	0.998	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.998	0.002
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.998	0.002
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.998	0.002
L81.8 Other specified disorders of pigmentation	0.002	0.998	0.000
S27.3 Other injuries of lung	0.000	0.998	0.002
L81.6 Other disorders of diminished melanin formation	0.002	0.998	0.000
L81.5 Leukoderma, not elsewhere classified	0.002	0.998	0.000
L81.3 Cafe au lait spots	0.002	0.998	0.000
L81.1 Chloasma	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.000	0.998	0.002
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.002
E26 Hyperaldosteronism	0.000	0.998	0.002
S27.8 Injury of other specified intrathoracic organs	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
Q82.0 Hereditary lymphoedema	0.000	0.998	0.002
O86.4 Pyrexia of unknown origin following delivery	0.000	0.998	0.002
E29.1 Testicular hypofunction	0.000	0.998	0.002
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.998	0.002
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.998	0.002
L81.0 Postinflammatory hyperpigmentation	0.002	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
G96.8 Other specified disorders of central nervous system	0.000	0.998	0.002
N02.8 Other	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.002
E25.8 Other adrenogenital disorders	0.000	0.998	0.002
G95 Other diseases of spinal cord	0.000	0.998	0.002
C65 Malignant neoplasm of renal pelvis	0.002	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.000	0.998	0.002
Q82.4 Ectodermal dysplasia (anhidrotic)	0.000	0.998	0.002
Q82.3 Incontinentia pigmenti	0.000	0.998	0.002
Q82.1 Xeroderma pigmentosum	0.000	0.998	0.002
E22 Hyperfunction of pituitary gland	0.000	0.998	0.002
R44.1 Visual hallucinations	0.000	0.998	0.002
W21.9 Unspecified place	0.002	0.998	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.998	0.002
G96.9 Disorder of central nervous system, unspecified	0.000	0.998	0.002
E28 Ovarian dysfunction	0.000	0.998	0.002
G30.1 Alzheimer's disease with late onset	0.000	0.998	0.002
H02.1 Ectropion of eyelid	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.998	0.002
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.998	0.002
Q82.2 Mastocytosis	0.000	0.998	0.002
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
C77.9 Lymph node, unspecified	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.998	0.002
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.998	0.002
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.998	0.002
Q87.4 Marfan's syndrome	0.000	0.998	0.002
S22.30 Fracture of rib (closed)	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
B17 Other acute viral hepatitis	0.000	0.998	0.002
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.998	0.002
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.998	0.002
H81.0 Meniere's disease	0.002	0.998	0.000
G30 Alzheimer's disease	0.000	0.998	0.002
M25.74 Osteophyte (Hand)	0.000	0.998	0.002
D35.0 Adrenal gland	0.000	0.998	0.002
G97.8 Other postprocedural disorders of nervous system	0.000	0.998	0.002
M25.4 Effusion of joint	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.002	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.998	0.002
D13.2 Duodenum	0.000	0.998	0.002
Z50.0 Cardiac rehabilitation	0.002	0.998	0.000
G90-G99 Other disorders of the nervous system	0.000	0.998	0.002
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.998	0.002
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.998	0.002
C77.8 Lymph nodes of multiple regions	0.000	0.998	0.002
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.998	0.002
Q89 Other congenital malformations, not elsewhere classified	0.000	0.998	0.002
Q80-Q89 Other congenital malformations	0.000	0.998	0.002
C77.4 Inguinal and lower limb lymph nodes	0.000	0.998	0.002
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.002
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.998	0.002
G95.2 Cord compression, unspecified	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.002
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
B17.8 Other specified acute viral hepatitis	0.000	0.998	0.002
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.002
B17.9 Acute viral hepatitis, unspecified	0.000	0.998	0.002
D22.5 Melanocytic naevi of trunk	0.000	0.998	0.002
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.002
E28.8 Other ovarian dysfunction	0.000	0.998	0.002
E28.1 Androgen excess	0.000	0.998	0.002
E28.0 Oestrogen excess	0.000	0.998	0.002
I31 Other diseases of pericardium	0.000	0.998	0.002
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.001
D13.0 Oesophagus	0.000	0.998	0.002
G30.8 Other Alzheimer's disease	0.000	0.998	0.002
A87 Viral meningitis	0.000	0.998	0.002
G95.9 Disease of spinal cord, unspecified	0.000	0.998	0.002
G95.0 Syringomyelia and syringobulbia	0.000	0.998	0.002
I08.0 Disorders of both mitral and aortic valves	0.002	0.998	0.000
D13.3 Other and unspecified parts of small intestine	0.000	0.998	0.002
G95.1 Vascular myelopathies	0.000	0.998	0.002
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.000	0.998	0.002
R41.3 Other amnesia	0.000	0.998	0.002
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.998	0.002
D13.5 Extrahepatic bile ducts	0.000	0.998	0.002
S42.0 Fracture of clavicle	0.002	0.998	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
I86.4 Gastric varices	0.000	0.998	0.002
K01.1 Impacted teeth	0.002	0.998	0.000
S60.2 Contusion of other parts of wrist and hand	0.000	0.998	0.002
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.998	0.002
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.998	0.002
Q89.3 Situs inversus	0.000	0.998	0.002
B17.2 Acute hepatitis E	0.000	0.998	0.002
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.002	0.998	0.000
E26.0 Primary hyperaldosteronism	0.000	0.998	0.001
M25.49 Effusion of joint (Site unspecified)	0.001	0.998	0.000
M25.48 Effusion of joint (Other)	0.001	0.998	0.000
M25.44 Effusion of joint (Hand)	0.001	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.001	0.998	0.000
M79.19 Myalgia (Site unspecified)	0.000	0.998	0.002
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.998	0.002
E87.7 Fluid overload	0.002	0.998	0.000
Q89.0 Congenital malformations of spleen	0.000	0.998	0.001
K75 Other inflammatory liver diseases	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.000	0.998	0.002
M25.43 Effusion of joint (Forearm)	0.001	0.998	0.000
Q24.0 Dextrocardia	0.002	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.000	0.998	0.001
Q89.8 Other specified congenital malformations	0.000	0.998	0.001
Q89.7 Multiple congenital malformations, not elsewhere classified	0.000	0.998	0.001
Q89.4 Conjoined twins	0.000	0.998	0.001
Q89.1 Congenital malformations of adrenal gland	0.000	0.998	0.001
S20.2 Contusion of thorax	0.000	0.998	0.002
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.000	0.998	0.002
Q84 Other congenital malformations of integument	0.000	0.998	0.002
Q81 Epidermolysis bullosa	0.000	0.998	0.002
I31.1 Chronic constrictive pericarditis	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.998	0.002
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.000	0.998	0.001
Q87.3 Congenital malformation syndromes involving early overgrowth	0.000	0.998	0.001
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.002	0.998	0.000
G92 Toxic encephalopathy	0.000	0.998	0.002
M40.26 Other and unspecified kyphosis (Lumbar region)	0.000	0.998	0.002
G30.0 Alzheimer's disease with early onset	0.000	0.998	0.002
G91.0 Communicating hydrocephalus	0.000	0.998	0.002
K75.3 Granulomatous hepatitis, not elsewhere classified	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.000	0.998	0.001
M25.42 Effusion of joint (Upper arm)	0.001	0.998	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.000	0.998	0.002
I31.0 Chronic adhesive pericarditis	0.000	0.998	0.001
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.000	0.998	0.002
M25.41 Effusion of joint (Shoulder region)	0.001	0.998	0.000
A87.2 Lymphocytic choriomeningitis	0.000	0.998	0.001
G94.1 Hydrocephalus in neoplastic disease	0.000	0.998	0.001
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.000	0.998	0.001
H80.9 Otosclerosis, unspecified	0.000	0.998	0.002
I31.8 Other specified diseases of pericardium	0.000	0.998	0.001
I31.2 Haemopericardium, not elsewhere classified	0.000	0.998	0.001
G90 Disorders of autonomic nervous system	0.000	0.998	0.001
Q24 Other congenital malformations of heart	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations