TreeWAS – Variant ID: rs6578985

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K86.1 Other chronic pancreatitis	0.000	0.933	0.067
K86 Other diseases of pancreas	0.000	0.956	0.044
K86.8 Other specified diseases of pancreas	0.000	0.959	0.041
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.959	0.041
K86.3 Pseudocyst of pancreas	0.000	0.970	0.030
Y84.8 Other medical procedures	0.000	0.978	0.022
K86.9 Disease of pancreas, unspecified	0.000	0.978	0.022
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.983	0.017
Y84.6 Urinary catheterisation	0.000	0.984	0.016
Y84.4 Aspiration of fluid	0.000	0.984	0.016
Y84.2 Radiological procedure and radiotherapy	0.000	0.985	0.015
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.986	0.014
Y84.3 Shock therapy	0.000	0.986	0.014
Y84.7 Blood-sampling	0.000	0.987	0.013
Y84.5 Insertion of gastric or duodenal sound	0.000	0.987	0.013
K86.2 Cyst of pancreas	0.000	0.989	0.011
Y84.9 Medical procedure, unspecified	0.000	0.989	0.011
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.989	0.011
Y84.1 Kidney dialysis	0.000	0.989	0.011
H65.4 Other chronic nonsuppurative otitis media	0.000	0.992	0.007
H65 Nonsuppurative otitis media	0.000	0.993	0.007
K66.0 Peritoneal adhesions	0.000	0.993	0.007
H65.2 Chronic serous otitis media	0.000	0.993	0.007
M81.9 Osteoporosis, unspecified	0.000	0.993	0.007
H65.3 Chronic mucoid otitis media	0.000	0.993	0.007
M79.09 Rheumatism, unspecified (Site unspecified)	0.006	0.994	0.000
H72 Perforation of tympanic membrane	0.000	0.994	0.006
M81.98 Osteoporosis, unspecified (Other)	0.000	0.994	0.006
H65.0 Acute serous otitis media	0.000	0.994	0.006
H65.1 Other acute nonsuppurative otitis media	0.000	0.994	0.006
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.994	0.006
H65-H75 Diseases of middle ear and mastoid	0.000	0.994	0.006
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.995	0.005
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.995	0.005
H72.1 Attic perforation of tympanic membrane	0.000	0.995	0.005
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.995	0.005
R00.2 Palpitations	0.000	0.995	0.005
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.995	0.005
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.995	0.005
H72.2 Other marginal perforations of tympanic membrane	0.000	0.995	0.005
H74.0 Tympanosclerosis	0.000	0.995	0.005
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.995	0.005
M81 Osteoporosis without pathological fracture	0.000	0.995	0.005
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.005	0.995	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.995	0.005
H70 Mastoiditis and related conditions	0.000	0.995	0.005
H74 Other disorders of middle ear and mastoid	0.000	0.995	0.005
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.995	0.005
Z03.4 Observation for suspected myocardial infarction	0.005	0.995	0.000
M85.8 Other specified disorders of bone density and structure	0.000	0.995	0.005
H68 Eustachian salpingitis and obstruction	0.000	0.995	0.005
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.995	0.005
G44.2 Tension-type headache	0.005	0.995	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.995	0.005
H66 Suppurative and unspecified otitis media	0.000	0.995	0.005
I27.0 Primary pulmonary hypertension	0.005	0.995	0.000
H70.1 Chronic mastoiditis	0.000	0.995	0.004
M85 Other disorders of bone density and structure	0.000	0.996	0.004
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.996	0.004
H72.8 Other perforations of tympanic membrane	0.000	0.996	0.004
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.996	0.004
H67 Otitis media in diseases classified elsewhere	0.000	0.996	0.004
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.004	0.996	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.996	0.004
M79.0 Rheumatism, unspecified	0.004	0.996	0.000
M81.1 Postoophorectomy osteoporosis	0.000	0.996	0.004
M79.00 Rheumatism, unspecified (Multiple sites)	0.004	0.996	0.000
H68.1 Obstruction of Eustachian tube	0.000	0.996	0.004
M85.0 Fibrous dysplasia (monostotic)	0.000	0.996	0.004
M80 Osteoporosis with pathological fracture	0.000	0.996	0.004
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.996	0.004
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.996	0.004
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.996	0.004
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.996	0.004
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.996	0.004
H66.4 Suppurative otitis media, unspecified	0.000	0.996	0.004
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.004	0.996	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
M80-M85 Disorders of bone density and structure	0.000	0.996	0.004
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.996	0.004
H70.0 Acute mastoiditis	0.000	0.996	0.004
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.996	0.004
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.996	0.004
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.996	0.004
M81.2 Osteoporosis of disuse	0.000	0.996	0.004
M85.6 Other cyst of bone	0.000	0.996	0.004
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.996	0.004
M81.6 Localised osteoporosis [Lequesne]	0.000	0.996	0.004
M81.5 Idiopathic osteoporosis	0.000	0.996	0.004
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.996	0.004
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.996	0.004
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.996	0.004
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.996	0.004
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.996	0.004
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.996	0.004
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.996	0.004
H70.2 Petrositis	0.000	0.996	0.004
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.996	0.004
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.996	0.004
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.996	0.004
H70.9 Mastoiditis, unspecified	0.000	0.996	0.004
C41.0 Bones of skull and face	0.004	0.996	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.996	0.004
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.996	0.004
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.996	0.004
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.996	0.004
M81.4 Drug-induced osteoporosis	0.000	0.996	0.004
C41.9 Bone and articular cartilage, unspecified	0.004	0.996	0.000
H68.0 Eustachian salpingitis	0.000	0.996	0.003
H70.8 Other mastoiditis and related conditions	0.000	0.996	0.004
C41.1 Mandible	0.004	0.996	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.996	0.004
M81.8 Other osteoporosis	0.000	0.996	0.003
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.996	0.003
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.996	0.004
C41.2 Vertebral column	0.003	0.996	0.000
C41.4 Pelvic bones, sacrum and coccyx	0.003	0.996	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.004	0.996	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.997	0.003
H69 Other disorders of Eustachian tube	0.000	0.997	0.003
M79.06 Rheumatism, unspecified (Lower leg)	0.003	0.997	0.000
M85.5 Aneurysmal bone cyst	0.000	0.997	0.003
M85.3 Osteitis condensans	0.000	0.997	0.003
M85.1 Skeletal fluorosis	0.000	0.997	0.003
H66.0 Acute suppurative otitis media	0.000	0.997	0.003
M85.64 Other cyst of bone (Hand)	0.000	0.997	0.003
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.997	0.003
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.997	0.003
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.997	0.003
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.997	0.003
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.997	0.003
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.997	0.003
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
M79.07 Rheumatism, unspecified (Ankle and foot)	0.003	0.997	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M79.04 Rheumatism, unspecified (Hand)	0.003	0.997	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.003	0.997	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.003	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.997	0.003
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.997	0.003
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.997	0.003
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.997	0.003
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.997	0.003
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.997	0.003
M85.4 Solitary bone cyst	0.000	0.997	0.003
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.000	0.997	0.003
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.000	0.997	0.003
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.000	0.997	0.003
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.000	0.997	0.003
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.000	0.997	0.003
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.000	0.997	0.003
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.000	0.997	0.003
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.997	0.003
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.997	0.003
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.997	0.003
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
G96.0 Cerebrospinal fluid leak	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.000	0.997	0.003
M81.0 Postmenopausal osteoporosis	0.000	0.997	0.003
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.997	0.003
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.997	0.003
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.997	0.003
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.997	0.003
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.997	0.003
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.997	0.003
I27 Other pulmonary heart diseases	0.003	0.997	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.000	0.997	0.003
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.000	0.997	0.003
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.997	0.003
M79.01 Rheumatism, unspecified (Shoulder region)	0.003	0.997	0.000
C41.3 Ribs, sternum and clavicle	0.003	0.997	0.000
C41.8 Overlapping lesion of bone and articular cartilage	0.003	0.997	0.000
N20.0 Calculus of kidney	0.000	0.997	0.003
H71 Cholesteatoma of middle ear	0.000	0.997	0.003
M79.08 Rheumatism, unspecified (Other)	0.003	0.997	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.997	0.003
M85.9 Disorder of bone density and structure, unspecified	0.000	0.997	0.003
M80.8 Other osteoporosis with pathological fracture	0.000	0.997	0.003
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.997	0.003
M81.28 Osteoporosis of disuse (Other)	0.000	0.997	0.003
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.997	0.003
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.997	0.003
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.997	0.003
M81.24 Osteoporosis of disuse (Hand)	0.000	0.997	0.003
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.997	0.003
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.997	0.003
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.997	0.003
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.997	0.003
M85.69 Other cyst of bone (Site unspecified)	0.000	0.997	0.003
M85.63 Other cyst of bone (Forearm)	0.000	0.997	0.003
M85.62 Other cyst of bone (Upper arm)	0.000	0.997	0.003
M85.61 Other cyst of bone (Shoulder region)	0.000	0.997	0.003
M85.60 Other cyst of bone (Multiple sites)	0.000	0.997	0.003
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.58 Idiopathic osteoporosis (Other)	0.000	0.997	0.003
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.997	0.003
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.997	0.003
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.997	0.003
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.997	0.003
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.997	0.003
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.997	0.003
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.997	0.003
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.997	0.003
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.997	0.003
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.997	0.003
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.997	0.003
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.997	0.003
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.997	0.003
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.997	0.003
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.997	0.003
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.997	0.003
H74.1 Adhesive middle ear disease	0.000	0.997	0.003
M85.2 Hyperostosis of skull	0.000	0.997	0.003
N36.2 Urethral caruncle	0.003	0.997	0.000
R47.1 Dysarthria and anarthria	0.003	0.997	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.997	0.003
M81.48 Drug-induced osteoporosis (Other)	0.000	0.997	0.003
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.997	0.003
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.997	0.003
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.997	0.003
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.997	0.003
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.997	0.003
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.003	0.997	0.000
I74.5 Embolism and thrombosis of iliac artery	0.003	0.997	0.000
M85.66 Other cyst of bone (Lower leg)	0.000	0.997	0.003
H53.0 Amblyopia ex anopsia	0.000	0.997	0.003
H74.4 Polyp of middle ear	0.000	0.997	0.003
M81.88 Other osteoporosis (Other)	0.000	0.997	0.003
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.86 Other osteoporosis (Lower leg)	0.000	0.997	0.003
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.84 Other osteoporosis (Hand)	0.000	0.997	0.003
M81.83 Other osteoporosis (Forearm)	0.000	0.997	0.003
M81.82 Other osteoporosis (Upper arm)	0.000	0.997	0.003
M81.81 Other osteoporosis (Shoulder region)	0.000	0.997	0.003
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.003
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
I27.2 Other secondary pulmonary hypertension	0.003	0.997	0.000
M83 Adult osteomalacia	0.000	0.997	0.003
M85.68 Other cyst of bone (Other)	0.000	0.997	0.003
K25.7 Chronic without haemorrhage or perforation	0.003	0.997	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.997	0.003
M81.89 Other osteoporosis (Site unspecified)	0.000	0.997	0.003
M75.1 Rotator cuff syndrome	0.000	0.997	0.003
L29.0 Pruritus ani	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
H69.0 Patulous Eustachian tube	0.000	0.997	0.003
Q61.0 Congenital single renal cyst	0.000	0.997	0.003
M85.19 Skeletal fluorosis (Site unspecified)	0.000	0.997	0.003
M85.18 Skeletal fluorosis (Other)	0.000	0.997	0.003
M85.17 Skeletal fluorosis (Ankle and foot)	0.000	0.997	0.003
M85.16 Skeletal fluorosis (Lower leg)	0.000	0.997	0.003
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.000	0.997	0.003
M85.14 Skeletal fluorosis (Hand)	0.000	0.997	0.003
M85.13 Skeletal fluorosis (Forearm)	0.000	0.997	0.003
M85.12 Skeletal fluorosis (Upper arm)	0.000	0.997	0.003
M85.11 Skeletal fluorosis (Shoulder region)	0.000	0.997	0.003
M85.10 Skeletal fluorosis (Multiple sites)	0.000	0.997	0.003
M85.39 Osteitis condensans (Site unspecified)	0.000	0.997	0.003
M85.38 Osteitis condensans (Other)	0.000	0.997	0.003
M85.37 Osteitis condensans (Ankle and foot)	0.000	0.997	0.003
M85.36 Osteitis condensans (Lower leg)	0.000	0.997	0.003
M85.35 Osteitis condensans (Pelvic region and thigh)	0.000	0.997	0.003
M85.34 Osteitis condensans (Hand)	0.000	0.997	0.003
M85.33 Osteitis condensans (Forearm)	0.000	0.997	0.003
M85.32 Osteitis condensans (Upper arm)	0.000	0.997	0.003
M85.31 Osteitis condensans (Shoulder region)	0.000	0.997	0.003
M85.30 Osteitis condensans (Multiple sites)	0.000	0.997	0.003
M85.59 Aneurysmal bone cyst (Site unspecified)	0.000	0.997	0.003
M85.58 Aneurysmal bone cyst (Other)	0.000	0.997	0.003
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.000	0.997	0.003
M85.56 Aneurysmal bone cyst (Lower leg)	0.000	0.997	0.003
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.000	0.997	0.003
M85.54 Aneurysmal bone cyst (Hand)	0.000	0.997	0.003
M85.53 Aneurysmal bone cyst (Forearm)	0.000	0.997	0.003
M85.52 Aneurysmal bone cyst (Upper arm)	0.000	0.997	0.003
M85.51 Aneurysmal bone cyst (Shoulder region)	0.000	0.997	0.003
M85.50 Aneurysmal bone cyst (Multiple sites)	0.000	0.997	0.003
G44.0 Cluster headache syndrome	0.003	0.997	0.000
I27.8 Other specified pulmonary heart diseases	0.003	0.997	0.000
N20.1 Calculus of ureter	0.000	0.997	0.003
G44 Other headache syndromes	0.003	0.997	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.997	0.003
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.003	0.997	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.997	0.003
M81.80 Other osteoporosis (Multiple sites)	0.000	0.997	0.002
I74 Arterial embolism and thrombosis	0.003	0.997	0.000
Y84.0 Cardiac catheterisation	0.001	0.997	0.002
M85.49 Solitary bone cyst (Site unspecified)	0.000	0.997	0.002
M85.48 Solitary bone cyst (Other)	0.000	0.997	0.002
M85.44 Solitary bone cyst (Hand)	0.000	0.997	0.002
M85.43 Solitary bone cyst (Forearm)	0.000	0.997	0.002
M85.42 Solitary bone cyst (Upper arm)	0.000	0.997	0.002
M85.41 Solitary bone cyst (Shoulder region)	0.000	0.997	0.002
M85.40 Solitary bone cyst (Multiple sites)	0.000	0.997	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.997	0.002
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.997	0.002
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.997	0.002
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.997	0.002
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.997	0.002
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.997	0.002
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.997	0.002
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.002
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.002
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.002
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.997	0.002
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.997	0.002
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.002
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.002
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.002
H69.9 Eustachian tube disorder, unspecified	0.000	0.997	0.003
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
M82 Osteoporosis in diseases classified elsewhere	0.000	0.997	0.002
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.997	0.002
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.997	0.002
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.997	0.002
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.997	0.002
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.997	0.002
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.997	0.002
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.997	0.002
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.997	0.002
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.000	0.997	0.002
M85.47 Solitary bone cyst (Ankle and foot)	0.000	0.997	0.002
M85.46 Solitary bone cyst (Lower leg)	0.000	0.997	0.002
G44.3 Chronic posttraumatic headache	0.003	0.997	0.000
I27.1 Kyphoscoliotic heart disease	0.002	0.997	0.000
O63.9 Long labour, unspecified	0.003	0.997	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.997	0.002
H66.3 Other chronic suppurative otitis media	0.000	0.997	0.003
H73 Other disorders of tympanic membrane	0.000	0.997	0.002
M85.98 Disorder of bone density and structure, unspecified (Other)	0.000	0.997	0.002
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.000	0.997	0.002
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.000	0.997	0.002
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.000	0.997	0.002
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.000	0.997	0.002
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.000	0.997	0.002
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.000	0.997	0.002
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.000	0.997	0.002
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.997	0.002
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.002
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.002
B00.5 Herpesviral ocular disease	0.000	0.997	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.997	0.002
I27.9 Pulmonary heart disease, unspecified	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.998	0.002
M85.29 Hyperostosis of skull-Site unspec	0.000	0.998	0.002
M85.28 Hyperostosis of skull-Other	0.000	0.998	0.002
M85.27 Hyperostosis of skull-Ankle/Foot	0.000	0.998	0.002
M85.26 Hyperostosis of skull-Lower Leg	0.000	0.998	0.002
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.000	0.998	0.002
M85.24 Hyperostosis of skull-Hand	0.000	0.998	0.002
M85.23 Hyperostosis of skull-Forearm	0.000	0.998	0.002
M85.21 Hyperostosis of skull-Shldr region	0.000	0.998	0.002
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M85.22 Hyperostosis of skull-Upper arm	0.000	0.998	0.002
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.998	0.002
G96.1 Disorders of meninges, not elsewhere classified	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.998	0.002
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
R23.2 Flushing	0.000	0.998	0.002
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
M83.9 Adult osteomalacia, unspecified	0.000	0.998	0.002
M83.8 Other adult osteomalacia	0.000	0.998	0.002
N20 Calculus of kidney and ureter	0.000	0.998	0.002
M83.5 Other drug-induced osteomalacia in adults	0.000	0.998	0.002
M83.4 Aluminum bone disease	0.000	0.998	0.002
M83.2 Adult osteomalacia due to malabsorption	0.000	0.998	0.002
M83.0 Puerperal osteomalacia	0.000	0.998	0.002
Z45.8 Adjustment and management of other implanted devices	0.002	0.998	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.000	0.998	0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.002	0.998	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.998	0.002
G96 Other disorders of central nervous system	0.002	0.998	0.000
M25.57 Pain in joint (Ankle and foot)	0.002	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M83.3 Adult osteomalacia due to malnutrition	0.000	0.998	0.002
M84.4 Pathological fracture, not elsewhere classified	0.000	0.998	0.002
Z83.5 Family history of eye and ear disorders	0.002	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
F80.1 Expressive language disorder	0.002	0.998	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.002	0.998	0.000
B00.1 Herpesviral vesicular dermatitis	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.000	0.998	0.002
G44.4 Drug-induced headache, not elsewhere classified	0.002	0.998	0.000
M83.1 Senile osteomalacia	0.000	0.998	0.002
C18.2 Ascending colon	0.002	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.000	0.998	0.002
M82.0 Osteoporosis in multiple myelomatosis	0.000	0.998	0.002
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.000	0.998	0.002
R27.8 Other and unspecified lack of coordination	0.002	0.998	0.000
G44.1 Vascular headache, not elsewhere classified	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.998	0.002
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.002	0.998	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.002	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.002	0.998	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.002	0.998	0.000
M85.20 Hyperostosis of skull-Mult sites	0.001	0.998	0.002
N18.9 Chronic renal failure, unspecified	0.002	0.998	0.000
N36 Other disorders of urethra	0.002	0.998	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.002	0.998	0.000
H73.1 Chronic myringitis	0.000	0.998	0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.998	0.002
S82.21 Fracture of shaft of tibia (open)	0.002	0.998	0.000
H73.0 Acute myringitis	0.000	0.998	0.002
G96.8 Other specified disorders of central nervous system	0.002	0.998	0.000
K55.9 Vascular disorder of intestine, unspecified	0.000	0.998	0.002
N36.1 Urethral diverticulum	0.002	0.998	0.000
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.000	0.998	0.002
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
M83.98 Adult osteomalacia, unspecified (Other)	0.000	0.998	0.002
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.000	0.998	0.002
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.000	0.998	0.002
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M83.94 Adult osteomalacia, unspecified (Hand)	0.000	0.998	0.002
M83.93 Adult osteomalacia, unspecified (Forearm)	0.000	0.998	0.002
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.000	0.998	0.002
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.000	0.998	0.002
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.000	0.998	0.002
N36.8 Other specified disorders of urethra	0.002	0.998	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.000	0.998	0.002
M83.08 Puerperal osteomalacia (Other)	0.000	0.998	0.002
M83.07 Puerperal osteomalacia (Ankle and foot)	0.000	0.998	0.002
M83.06 Puerperal osteomalacia (Lower leg)	0.000	0.998	0.002
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.000	0.998	0.002
M83.04 Puerperal osteomalacia (Hand)	0.000	0.998	0.002
M83.03 Puerperal osteomalacia (Forearm)	0.000	0.998	0.002
M83.02 Puerperal osteomalacia (Upper arm)	0.000	0.998	0.002
M83.01 Puerperal osteomalacia (Shoulder region)	0.000	0.998	0.002
M83.00 Puerperal osteomalacia (Multiple sites)	0.000	0.998	0.002
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.000	0.998	0.002
M83.28 Adult osteomalacia due to malabsorption (Other)	0.000	0.998	0.002
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.000	0.998	0.002
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.000	0.998	0.002
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.000	0.998	0.002
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.000	0.998	0.002
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.000	0.998	0.002
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.000	0.998	0.002
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.000	0.998	0.002
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.000	0.998	0.002
M83.49 Aluminium bone disease (Site unspecified)	0.000	0.998	0.002
M83.48 Aluminium bone disease (Other)	0.000	0.998	0.002
M83.47 Aluminium bone disease (Ankle and foot)	0.000	0.998	0.002
M83.46 Aluminium bone disease (Lower leg)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations