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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6586
log Bayes Factor = 13.6487
Chromosome 9   position 100,666,931  (GRCh37) Explore rs6586 on Ensembl!
Variant rs6586 is part of Cluster X0103

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E04.2 Non-toxic multinodular goitre
1.000 0.000 0.000
E04 Other non-toxic goitre
0.996 0.004 0.000
E03 Other hypothyroidism
0.995 0.005 0.000
E00-E07 Disorders of thyroid gland
0.991 0.009 0.000
E04.9 Non-toxic goitre, unspecified
0.940 0.060 0.000
E03.8 Other specified hypothyroidism
0.772 0.228 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.740 0.260 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.715 0.285 0.000
E04.8 Other specified non-toxic goitre
0.714 0.286 0.000
E03.5 Myxoedema coma
0.714 0.286 0.000
E03.4 Atrophy of thyroid (acquired)
0.714 0.286 0.000
E03.3 Postinfectious hypothyroidism
0.714 0.286 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.711 0.289 0.000
E00 Congenital iodine-deficiency syndrome
0.711 0.289 0.000
E03.1 Congenital hypothyroidism without goitre
0.689 0.311 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.676 0.324 0.000
E04.0 Non-toxic diffuse goitre
0.673 0.326 0.000
C73 Malignant neoplasm of thyroid gland
0.000 0.371 0.629
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.509 0.490 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.509 0.490 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.509 0.490 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.509 0.490 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.509 0.490 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.509 0.490 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.509 0.490 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.509 0.490 0.000
B37.8 Candidiasis of other sites
0.000 0.506 0.494
E06 Thyroiditis
0.494 0.506 0.000
E07 Other disorders of thyroid
0.481 0.518 0.000
B37 Candidiasis
0.000 0.572 0.428
B37.0 Candidal stomatitis
0.000 0.595 0.405
B37.1 Pulmonary candidiasis
0.000 0.617 0.383
E06.5 Other chronic thyroiditis
0.373 0.627 0.000
E06.4 Drug-induced thyroiditis
0.354 0.646 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.354 0.646 0.000
E06.0 Acute thyroiditis
0.354 0.646 0.000
E07.1 Dyshormogenetic goitre
0.345 0.655 0.000
E07.0 Hypersecretion of calcitonin
0.345 0.655 0.000
E06.1 Subacute thyroiditis
0.337 0.663 0.000
B37.2 Candidiasis of skin and nail
0.000 0.666 0.334
E07.8 Other specified disorders of thyroid
0.327 0.672 0.000
B37.4 Candidiasis of other urogenital sites
0.000 0.675 0.325
E05 Thyrotoxicosis [hyperthyroidism]
0.324 0.676 0.000
B37.6 Candidal endocarditis
0.000 0.693 0.307
B37.5 Candidal meningitis
0.000 0.693 0.307
E06.9 Thyroiditis, unspecified
0.306 0.694 0.000
B37.7 Candidal septicaemia
0.000 0.710 0.289
B37.3 Candidiasis of vulva and vagina
0.000 0.731 0.269
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.246 0.754 0.000
E05.8 Other thyrotoxicosis
0.243 0.757 0.000
E05.5 Thyroid crisis or storm
0.232 0.767 0.000
E05.4 Thyrotoxicosis factitia
0.232 0.767 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.232 0.767 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.232 0.767 0.000
B37.9 Candidiasis, unspecified
0.000 0.778 0.221
E06.3 Autoimmune thyroiditis
0.218 0.781 0.000
E04.1 Non-toxic single thyroid nodule
0.207 0.792 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.797 0.203
E07.9 Disorder of thyroid, unspecified
0.158 0.842 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.856 0.144
E05.0 Thyrotoxicosis with diffuse goitre
0.121 0.879 0.000
C74 Malignant neoplasm of adrenal gland
0.000 0.881 0.118
C75.9 Endocrine gland, unspecified
0.000 0.891 0.108
C75.8 Pluriglandular involvement, unspecified
0.000 0.897 0.103
C75.5 Aortic body and other paraganglia
0.000 0.897 0.103
C75.4 Carotid body
0.000 0.897 0.103
C75.3 Pineal gland
0.000 0.897 0.103
C75.2 Craniopharyngeal duct
0.000 0.897 0.103
C75.0 Parathyroid gland
0.000 0.897 0.103
C75.1 Pituitary gland
0.000 0.904 0.095
C74.1 Medulla of adrenal gland
0.000 0.917 0.082
C74.0 Cortex of adrenal gland
0.000 0.921 0.079
C74.9 Adrenal gland, unspecified
0.000 0.929 0.071
B35-B49 Mycoses
0.000 0.951 0.049
Chapter IV Endocrine, nutritional and metabolic diseases
0.042 0.958 0.000
E05.9 Thyrotoxicosis, unspecified
0.039 0.961 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.000 0.964 0.036
E10-E14 Diabetes mellitus
0.035 0.965 0.000
B48 Other mycoses, not elsewhere classified
0.000 0.965 0.035
B47 Mycetoma
0.000 0.965 0.035
B46 Zygomycosis
0.000 0.965 0.035
B45 Cryptococcosis
0.000 0.965 0.035
B43 Chromomycosis and phaeomycotic abscess
0.000 0.965 0.035
B42 Sporotrichosis
0.000 0.965 0.035
B41 Paracoccidioidomycosis
0.000 0.965 0.035
B40 Blastomycosis
0.000 0.965 0.035
B39 Histoplasmosis
0.000 0.965 0.035
B38 Coccidioidomycosis
0.000 0.965 0.035
E14.3 With ophthalmic complications
0.033 0.967 0.000
E20-E35 Disorders of other endocrine glands
0.033 0.967 0.000
E14 Unspecified diabetes mellitus
0.032 0.968 0.000
B49 Unspecified mycosis
0.000 0.969 0.030
B44 Aspergillosis
0.000 0.970 0.030
E24 Cushing's syndrome
0.029 0.970 0.000
E10 Insulin-dependent diabetes mellitus
0.029 0.971 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.028 0.972 0.000
E10.3 With ophthalmic complications
0.028 0.972 0.000
B36 Other superficial mycoses
0.000 0.972 0.027
E26 Hyperaldosteronism
0.027 0.972 0.000
E14.2 Withrenal complications
0.027 0.973 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.027 0.973 0.000
E13 Other specified diabetes mellitus
0.027 0.973 0.000
E14.8 With unspecified complications
0.026 0.974 0.000
E12 Malnutrition-related diabetes mellitus
0.026 0.974 0.000
E29 Testicular dysfunction
0.026 0.974 0.000
B38.9 Coccidioidomycosis, unspecified
0.000 0.974 0.025
B38.8 Other forms of coccidioidomycosis
0.000 0.974 0.025
B38.7 Disseminated coccidioidomycosis
0.000 0.974 0.025
B38.4 Coccidioidomycosis meningitis
0.000 0.974 0.025
B38.3 Cutaneous coccidioidomycosis
0.000 0.974 0.025
B38.2 Pulmonary coccidioidomycosis, unspecified
0.000 0.974 0.025
B38.1 Chronic pulmonary coccidioidomycosis
0.000 0.974 0.025
B38.0 Acute pulmonary coccidioidomycosis
0.000 0.974 0.025
B39.9 Histoplasmosis, unspecified
0.000 0.974 0.025
B39.5 Histoplasmosis duboisii
0.000 0.974 0.025
B39.4 Histoplasmosis capsulati, unspecified
0.000 0.974 0.025
B39.3 Disseminated histoplasmosis capsulati
0.000 0.974 0.025
B39.2 Pulmonary histoplasmosis capsulati, unspecified
0.000 0.974 0.025
B39.1 Chronic pulmonary histoplasmosis capsulati
0.000 0.974 0.025
B39.0 Acute pulmonary histoplasmosis capsulati
0.000 0.974 0.025
B40.9 Blastomycosis, unspecified
0.000 0.974 0.025
B40.8 Other forms of blastomycosis
0.000 0.974 0.025
B40.7 Disseminated blastomycosis
0.000 0.974 0.025
B40.3 Cutaneous blastomycosis
0.000 0.974 0.025
B40.2 Pulmonary blastomycosis, unspecified
0.000 0.974 0.025
B40.1 Chronic pulmonary blastomycosis
0.000 0.974 0.025
B40.0 Acute pulmonary blastomycosis
0.000 0.974 0.025
B41.9 Paracoccidioidomycosis, unspecified
0.000 0.974 0.025
B41.8 Other forms of paracoccidioidomycosis
0.000 0.974 0.025
B41.7 Disseminated paracoccidioidomycosis
0.000 0.974 0.025
B41.0 Pulmonary paracoccidioidomycosis
0.000 0.974 0.025
B42.9 Sporotrichosis, unspecified
0.000 0.974 0.025
B42.8 Other forms of sporotrichosis
0.000 0.974 0.025
B42.7 Disseminated sporotrichosis
0.000 0.974 0.025
B42.1 Lymphocutaneous sporotrichosis
0.000 0.974 0.025
B42.0 Pulmonary sporotrichosis
0.000 0.974 0.025
B43.9 Chromomycosis, unspecified
0.000 0.974 0.025
B43.8 Other forms of chromomycosis
0.000 0.974 0.025
B43.2 Subcutaneous phaeomycotic abscess and cyst
0.000 0.974 0.025
B43.1 Phaeomycotic brain abscess
0.000 0.974 0.025
B43.0 Cutaneous chromomycosis
0.000 0.974 0.025
B45.9 Cryptococcosis, unspecified
0.000 0.974 0.025
B45.8 Other forms of cryptococcosis
0.000 0.974 0.025
B45.7 Disseminated cryptococcosis
0.000 0.974 0.025
B45.3 Osseous cryptococcosis
0.000 0.974 0.025
B45.2 Cutaneous cryptococcosis
0.000 0.974 0.025
B45.1 Cerebral cryptococcosis
0.000 0.974 0.025
B45.0 Pulmonary cryptococcosis
0.000 0.974 0.025
B46.9 Zygomycosis, unspecified
0.000 0.974 0.025
B46.8 Other zygomycoses
0.000 0.974 0.025
B46.5 Mucormycosis, unspecified
0.000 0.974 0.025
B46.4 Disseminated mucormycosis
0.000 0.974 0.025
B46.3 Cutaneous mucormycosis
0.000 0.974 0.025
B46.2 Gastro-intestinal mucormycosis
0.000 0.974 0.025
B46.1 Rhinocerebral mucormycosis
0.000 0.974 0.025
B46.0 Pulmonary mucormycosis
0.000 0.974 0.025
B47.9 Mycetoma, unspecified
0.000 0.974 0.025
B47.1 Actinomycetoma
0.000 0.974 0.025
B47.0 Eumycetoma
0.000 0.974 0.025
B48.8 Other specified mycoses
0.000 0.974 0.025
B48.7 Opportunistic mycoses
0.000 0.974 0.025
B48.4 Penicillosis
0.000 0.974 0.025
B48.3 Geotrichosis
0.000 0.974 0.025
B48.2 Allescheriasis
0.000 0.974 0.025
B48.1 Rhinosporidiosis
0.000 0.974 0.025
B48.0 Lobomycosis
0.000 0.974 0.025
E24.9 Cushing's syndrome, unspecified
0.025 0.975 0.000
E24.0 Pituitary-dependent Cushing's disease
0.025 0.975 0.000
E14.6 With other specified complications
0.025 0.975 0.000
E25 Adrenogenital disorders
0.025 0.975 0.000
E26.0 Primary hyperaldosteronism
0.024 0.976 0.000
E40-E46 Malnutrition
0.024 0.976 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.024 0.976 0.000
E32 Diseases of thymus
0.024 0.976 0.000
E31 Polyglandular dysfunction
0.024 0.976 0.000
E30 Disorders of puberty, not elsewhere classified
0.024 0.976 0.000
E10.8 With unspecified complications
0.024 0.976 0.000
E14.7 With multiple complications
0.023 0.976 0.000
E14.0 With coma
0.023 0.976 0.000
E10.4 With neurological complications
0.024 0.976 0.000
E10.6 With other specified complications
0.023 0.977 0.000
E14.1 With ketoacidosis
0.023 0.977 0.000
E28 Ovarian dysfunction
0.023 0.977 0.000
B44.9 Aspergillosis, unspecified
0.000 0.977 0.023
E21.0 Primary hyperparathyroidism
0.023 0.977 0.000
E34 Other endocrine disorders
0.022 0.977 0.000
E21.4 Other specified disorders of parathyroid gland
0.022 0.978 0.000
B44.8 Other forms of aspergillosis
0.000 0.978 0.022
B44.7 Disseminated aspergillosis
0.000 0.978 0.022
B44.2 Tonsillar aspergillosis
0.000 0.978 0.022
B44.0 Invasive pulmonary aspergillosis
0.000 0.978 0.022
E14.5 With peripheral circulatory complications
0.022 0.978 0.000
E24.8 Other Cushing's syndrome
0.022 0.978 0.000
E23 Hypofunction and other disorders of pituitary gland
0.022 0.978 0.000
E10.7 With multiple complications
0.022 0.978 0.000
E10.0 With coma
0.022 0.978 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.021 0.979 0.000
E24.3 Ectopic ACTH syndrome
0.021 0.979 0.000
E24.1 Nelson's syndrome
0.021 0.979 0.000
E13.3 With ophthalmic complications
0.021 0.979 0.000
E24.2 Drug-induced Cushing's syndrome
0.021 0.979 0.000
E14.4 With neurological complications
0.020 0.979 0.000
E15 Nondiabetic hypoglycaemic coma
0.020 0.979 0.000
E21.3 Hyperparathyroidism, unspecified
0.020 0.980 0.000
E29.9 Testicular dysfunction, unspecified
0.020 0.980 0.000
B36.8 Other specified superficial mycoses
0.000 0.980 0.020
B36.3 Black piedra
0.000 0.980 0.020
B36.2 White piedra
0.000 0.980 0.020
B36.1 Tinea nigra
0.000 0.980 0.020
B36.0 Pityriasis versicolor
0.000 0.980 0.020
E20 Hypoparathyroidism
0.020 0.980 0.000
G91.9 Hydrocephalus, unspecified
0.000 0.980 0.020
E26.9 Hyperaldosteronism, unspecified
0.020 0.980 0.000
E26.8 Other hyperaldosteronism
0.020 0.980 0.000
E26.1 Secondary hyperaldosteronism
0.020 0.980 0.000
E34.9 Endocrine disorder, unspecified
0.020 0.980 0.000
E21.2 Other hyperparathyroidism
0.020 0.980 0.000
B35 Dermatophytosis
0.000 0.980 0.019
E13.8 With unspecified complications
0.019 0.981 0.000
E13.7 With multiple complications
0.019 0.981 0.000
E13.6 With other specified complications
0.019 0.981 0.000
E13.5 With peripheral circulatory complications
0.019 0.981 0.000
E13.4 With neurological complications
0.019 0.981 0.000
E13.2 With renal complications
0.019 0.981 0.000
E13.1 With ketoacidosis
0.019 0.981 0.000
E13.0 With coma
0.019 0.981 0.000
E23.2 Diabetes insipidus
0.019 0.981 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.019 0.981 0.000
E29.1 Testicular hypofunction
0.019 0.981 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.019 0.981 0.000
E13.9 Without complications
0.019 0.981 0.000
E12.9 Without complications
0.018 0.981 0.000
E12.8 With unspecified complications
0.018 0.981 0.000
E12.7 With multiple complications
0.018 0.981 0.000
E12.6 With other specified complications
0.018 0.981 0.000
E12.5 With peripheral circulatory complications
0.018 0.981 0.000
E12.4 With neurological complications
0.018 0.981 0.000
E12.3 With ophthalmic complications
0.018 0.981 0.000
E12.2 With renal complications
0.018 0.981 0.000
E12.1 With ketoacidosis
0.018 0.981 0.000
E12.0 With coma
0.018 0.981 0.000
E29.8 Other testicular dysfunction
0.018 0.981 0.000
E29.0 Testicular hyperfunction
0.018 0.981 0.000
E10.2 With renal complications
0.018 0.982 0.000
E16 Other disorders of pancreatic internal secretion
0.018 0.982 0.000
E25.9 Adrenogenital disorder, unspecified
0.018 0.982 0.000
E25.8 Other adrenogenital disorders
0.018 0.982 0.000
E10.5 With peripheral circulatory complications
0.018 0.982 0.000
E28.3 Primary ovarian failure
0.017 0.983 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.017 0.983 0.000
E45 Retarded development following protein-energy malnutrition
0.017 0.983 0.000
E43 Unspecified severe protein-energy malnutrition
0.017 0.983 0.000
E42 Marasmic kwashiorkor
0.017 0.983 0.000
E41 Nutritional marasmus
0.017 0.983 0.000
E40 Kwashiorkor
0.017 0.983 0.000
E30.9 Disorder of puberty, unspecified
0.017 0.983 0.000
E30.8 Other disorders of puberty
0.017 0.983 0.000
E30.1 Precocious puberty
0.017 0.983 0.000
E30.0 Delayed puberty
0.017 0.983 0.000
E31.9 Polyglandular dysfunction, unspecified
0.017 0.983 0.000
E31.8 Other polyglandular dysfunction
0.017 0.983 0.000
E31.1 Polyglandular hyperfunction
0.017 0.983 0.000
E31.0 Autoimmune polyglandular failure
0.017 0.983 0.000
E32.9 Disease of thymus, unspecified
0.017 0.983 0.000
E32.8 Other diseases of thymus
0.017 0.983 0.000
E32.1 Abscess of thymus
0.017 0.983 0.000
E32.0 Persistent hyperplasia of thymus
0.017 0.983 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.017 0.983 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.017 0.983 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.017 0.983 0.000
E28.9 Ovarian dysfunction, unspecified
0.017 0.983 0.000
E28.8 Other ovarian dysfunction
0.017 0.983 0.000
E28.1 Androgen excess
0.017 0.983 0.000
E28.0 Oestrogen excess
0.017 0.983 0.000
E34.5 Androgen resistance syndrome
0.016 0.984 0.000
E34.4 Constitutional tall stature
0.016 0.984 0.000
E34.3 Short stature, not elsewhere classified
0.016 0.984 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.016 0.984 0.000
E34.1 Other hypersecretion of intestinal hormones
0.016 0.984 0.000
B44.1 Other pulmonary aspergillosis
0.000 0.984 0.016
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.016 0.984 0.000
E23.1 Drug-induced hypopituitarism
0.016 0.984 0.000
E27 Other disorders of adrenal gland
0.016 0.984 0.000
B35.6 Tinea cruris
0.000 0.984 0.015
E65-E68 Obesity and other hyperalimentation
0.015 0.985 0.000
E20.1 Pseudohypoparathyroidism
0.015 0.985 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.015 0.985 0.000
E28.2 Polycystic ovarian syndrome
0.015 0.985 0.000
E23.0 Hypopituitarism
0.015 0.985 0.000
E20.8 Other hypoparathyroidism
0.015 0.985 0.000
E20.0 Idiopathic hypoparathyroidism
0.015 0.985 0.000
E23.7 Disorder of pituitary gland, unspecified
0.015 0.985 0.000
B35.8 Other dermatophytoses
0.000 0.986 0.014
B35.5 Tinea imbricata
0.000 0.986 0.014
B35.2 Tinea manuum
0.000 0.986 0.014
B35.0 Tinea barbae and tinea capitis
0.000 0.986 0.014
E16.0 Drug-induced hypoglycaemia without coma
0.014 0.986 0.000
B35.1 Tinea unguium
0.000 0.986 0.013
C34.1 Upper lobe, bronchus or lung
0.014 0.986 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.013 0.987 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.013 0.987 0.000
E16.4 Abnormal secretion of gastrin
0.013 0.987 0.000
E16.3 Increased secretion of glucagon
0.013 0.987 0.000
E34.8 Other specified endocrine disorders
0.013 0.987 0.000
E27.2 Addisonian crisis
0.013 0.987 0.000
E22 Hyperfunction of pituitary gland
0.013 0.987 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.013 0.987 0.000
B36.9 Superficial mycosis, unspecified
0.001 0.987 0.012
B35.9 Dermatophytosis, unspecified
0.001 0.987 0.012
E44.1 Mild protein-energy malnutrition
0.012 0.987 0.000
E44.0 Moderate protein-energy malnutrition
0.012 0.987 0.000
B35.4 Tinea corporis
0.001 0.987 0.012
C34.0 Main bronchus
0.013 0.987 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.012 0.988 0.000
E16.1 Other hypoglycaemia
0.012 0.988 0.000
E34.0 Carcinoid syndrome
0.012 0.988 0.000
N85.4 Malposition of uterus
0.012 0.988 0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation
0.000 0.988 0.012
E27.5 Adrenomedullary hyperfunction
0.011 0.988 0.000
E27.0 Other adrenocortical overactivity
0.011 0.988 0.000
Z95.4 Presence of other heart-valve replacement
0.000 0.988 0.012
E10.9 Without complications
0.011 0.989 0.000
N10 Acute tubulo-interstitial nephritis
0.011 0.989 0.000
E67 Other hyperalimentation
0.011 0.989 0.000
E68 Sequelae of hyperalimentation
0.011 0.989 0.000
E27.1 Primary adrenocortical insufficiency
0.011 0.989 0.000
E16.2 Hypoglycaemia, unspecified
0.011 0.989 0.000
E23.6 Other disorders of pituitary gland
0.011 0.989 0.000
E11 Non-insulin-dependent diabetes mellitus
0.011 0.989 0.000
I44.1 Atrioventricular block, second degree
0.000 0.989 0.011
E11.5 With peripheral circulatory complications
0.011 0.989 0.000
E46 Unspecified protein-energy malnutrition
0.010 0.989 0.000
C34 Malignant neoplasm of bronchus and lung
0.010 0.990 0.000
E22.1 Hyperprolactinaemia
0.010 0.990 0.000
E20.9 Hypoparathyroidism, unspecified
0.010 0.990 0.000
R20 Disturbances of skin sensation
0.000 0.990 0.010
E27.8 Other specified disorders of adrenal gland
0.010 0.990 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.009 0.990 0.000
E22.8 Other hyperfunction of pituitary gland
0.009 0.990 0.000
X62.9 Unspecified place
0.000 0.991 0.009
E27.4 Other and unspecified adrenocortical insufficiency
0.009 0.991 0.000
E65 Localised adiposity
0.009 0.991 0.000
O14.0 Moderate preeclampsia
0.009 0.991 0.000
C34.8 Overlapping lesion of bronchus and lung
0.009 0.991 0.000
Z31 Procreative management
0.000 0.991 0.009
X49.9 Unspecified place
0.009 0.991 0.000
E11.3 With ophthalmic complications
0.009 0.991 0.000
C34.2 Middle lobe, bronchus or lung
0.009 0.991 0.000
E50-E64 Other nutritional deficiencies
0.009 0.991 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.009 0.991 0.000
R20.3 Hyperaesthesia
0.000 0.991 0.009
E67.8 Other specified hyperalimentation
0.008 0.992 0.000
E67.3 Hypervitaminosis D
0.008 0.992 0.000
E67.2 Megavitamin-B6 syndrome
0.008 0.992 0.000
E67.1 Hypercarotenaemia
0.008 0.992 0.000
E67.0 Hypervitaminosis A
0.008 0.992 0.000
Z31.2 In vitro fertilisation
0.000 0.992 0.008
E70-E90 Metabolic disorders
0.008 0.992 0.000
E11.7 With multiple complications
0.008 0.992 0.000
S22.10 Multiple fractures of thoracic spine (closed)
0.000 0.992 0.008
Z31.8 Other procreative management
0.000 0.992 0.008
R20.0 Anaesthesia of skin
0.000 0.992 0.008
O14.9 Preeclampsia, unspecified
0.008 0.992 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.008 0.992 0.000
E11.6 With other specified complications
0.008 0.992 0.000
C44.1 Skin of eyelid, including canthus
0.000 0.992 0.008
E89.0 Postprocedural hypothyroidism
0.008 0.992 0.000
E72 Other disorders of amino-acid metabolism
0.008 0.992 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.008 0.992 0.000
R20.1 Hypoaesthesia of skin
0.000 0.992 0.007
E89.1 Postprocedural hypoinsulinaemia
0.008 0.992 0.000
I35.1 Aortic (valve) insufficiency
0.000 0.992 0.008
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.007 0.992 0.000
E74 Other disorders of carbohydrate metabolism
0.007 0.993 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.007 0.993 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.007 0.993 0.000
E11.1 With ketoacidosis
0.007 0.993 0.000
E89.4 Postprocedural ovarian failure
0.007 0.993 0.000
E84 Cystic fibrosis
0.007 0.993 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.007 0.993 0.000
S22.40 Multiple fractures of ribs (closed)
0.000 0.993 0.007
E51 Thiamine deficiency
0.007 0.993 0.000
Z31.3 Other assisted fertilisation methods
0.000 0.993 0.007
N85.2 Hypertrophy of uterus
0.007 0.993 0.000
E11.4 With neurological complications
0.007 0.993 0.000
E72.0 Disorders of amino-acid transport
0.007 0.993 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.007 0.993 0.000
S22.1 Multiple fractures of thoracic spine
0.000 0.993 0.007
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.007 0.993 0.000
E11.0 With coma
0.007 0.993 0.000
N85.7 Haematometra
0.007 0.993 0.000
C45.0 Mesothelioma of pleura
0.000 0.993 0.007
Z31.5 Genetic counselling
0.000 0.993 0.006
Z31.1 Artifical insemination
0.000 0.993 0.006
E10.1 With ketoacidosis
0.006 0.993 0.000
Z31.6 General counselling and advice on procreation
0.000 0.993 0.006
E64 Sequelae of malnutrition and other nutritional deficiencies
0.006 0.994 0.000
E63 Other nutritional deficiencies
0.006 0.994 0.000
E50 Vitamin A deficiency
0.006 0.994 0.000
E60 Dietary zinc deficiency
0.006 0.994 0.000
E59 Dietary selenium deficiency
0.006 0.994 0.000
E54 Ascorbic acid deficiency
0.006 0.994 0.000
E52 Niacin deficiency [pellagra]
0.006 0.994 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.006 0.994 0.000
E89.5 Postprocedural testicular hypofunction
0.006 0.994 0.000
C45.9 Mesothelioma, unspecified
0.000 0.994 0.006
E89.3 Postprocedural hypopituitarism
0.006 0.994 0.000
E11.2 With renal complications
0.006 0.994 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.006 0.994 0.000
N85.1 Endometrial adenomatous hyperplasia
0.006 0.994 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.994 0.006
N85.0 Endometrial glandular hyperplasia
0.006 0.994 0.000
E77 Disorders of glycoprotein metabolism
0.006 0.994 0.000
E76 Disorders of glycosaminoglycan metabolism
0.006 0.994 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.006 0.994 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.006 0.994 0.000
E27.9 Disorder of adrenal gland, unspecified
0.006 0.994 0.000
S22.4 Multiple fractures of ribs
0.000 0.994 0.006
Z31.9 Procreative management, unspecified
0.000 0.994 0.006
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.000 0.994 0.006
N85.6 Intra-uterine synechiae
0.006 0.994 0.000
E70 Disorders of aromatic amino-acid metabolism
0.006 0.994 0.000
I35 Nonrheumatic aortic valve disorders
0.000 0.994 0.006
C45 Mesothelioma
0.000 0.994 0.006
I35.9 Aortic valve disorder, unspecified
0.000 0.994 0.006
Z31.4 Procreative investigation and testing
0.000 0.994 0.006
E89.2 Postprocedural hypoparathyroidism
0.006 0.994 0.000
N85.5 Inversion of uterus
0.006 0.994 0.000
N85.3 Subinvolution of uterus
0.006 0.994 0.000
E56 Other vitamin deficiencies
0.006 0.994 0.000
E22.0 Acromegaly and pituitary gigantism
0.005 0.994 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.006 0.994 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.006 0.994 0.000
E72.5 Disorders of glycine metabolism
0.006 0.994 0.000
E72.4 Disorders of ornithine metabolism
0.006 0.994 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.006 0.994 0.000
E72.2 Disorders of urea cycle metabolism
0.006 0.994 0.000
E79 Disorders of purine and pyrimidine metabolism
0.006 0.994 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.006 0.994 0.000
O14.2 HELLP syndrome
0.006 0.994 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.000 0.994 0.006
S22.00 Fracture of thoracic vertebra (closed)
0.000 0.994 0.006
E75.2 Other sphingolipidosis
0.005 0.994 0.000
E84.9 Cystic fibrosis, unspecified
0.005 0.994 0.000
S22.0 Fracture of thoracic vertebra
0.000 0.994 0.005
E51.2 Wernicke's encephalopathy
0.005 0.994 0.000
B35.3 Tinea pedis
0.001 0.995 0.004
C45.7 Mesothelioma of other sites
0.000 0.995 0.005
E83 Disorders of mineral metabolism
0.005 0.995 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.005 0.995 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.005 0.995 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.005 0.995 0.000
E74.2 Disorders of galactose metabolism
0.005 0.995 0.000
E74.1 Disorders of fructose metabolism
0.005 0.995 0.000
E74.0 Glycogen storage disease
0.005 0.995 0.000
A08.4 Viral intestinal infection, unspecified
0.000 0.995 0.005
E11.8 With unspecified complications
0.005 0.995 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.005 0.995 0.000
E83.3 Disorders of phosphorus metabolism
0.005 0.995 0.000
E84.8 Cystic fibrosis with other manifestations
0.005 0.995 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.005 0.995 0.000
E75.5 Other lipid storage disorders
0.005 0.995 0.000
E58 Dietary calcium deficiency
0.005 0.995 0.000
E51.9 Thiamine deficiency, unspecified
0.005 0.995 0.000
E51.8 Other manifestations of thiamine deficiency
0.005 0.995 0.000
E51.1 Beriberi
0.005 0.995 0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
E75.6 Lipid storage disorder, unspecified
0.005 0.995 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.005 0.995 0.000
E75.3 Sphingolipidosis, unspecified
0.005 0.995 0.000
E75.1 Other gangliosidosis
0.005 0.995 0.000
E75.0 GM2 gangliosidosis
0.005 0.995 0.000
S22.11 Multiple fractures of thoracic spine (open)
0.000 0.995 0.005
Y57.9 Drug or medicament, unspecified
0.000 0.995 0.005
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.005 0.995 0.000
E50.9 Vitamin A deficiency, unspecified
0.005 0.995 0.000
E50.8 Other manifestations of vitamin A deficiency
0.005 0.995 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.005 0.995 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.005 0.995 0.000
E50.5 Vitamin A deficiency with night blindness
0.005 0.995 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.005 0.995 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.005 0.995 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.005 0.995 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.005 0.995 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.005 0.995 0.000
E63.9 Nutritional deficiency, unspecified
0.005 0.995 0.000
E63.8 Other specified nutritional deficiencies
0.005 0.995 0.000
E63.1 Imbalance of constituents of food intake
0.005 0.995 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.005 0.995 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.005 0.995 0.000
E64.8 Sequelae of other nutritional deficiencies
0.005 0.995 0.000
E64.3 Sequelae of rickets
0.005 0.995 0.000
E64.2 Sequelae of vitamin C deficiency
0.005 0.995 0.000
E64.1 Sequelae of vitamin A deficiency
0.005 0.995 0.000
E64.0 Sequelae of protein-energy malnutrition
0.005 0.995 0.000
E73 Lactose intolerance
0.005 0.995 0.000
E61 Deficiency of other nutrient elements
0.005 0.995 0.000
E55 Vitamin D deficiency
0.005 0.995 0.000
E85 Amyloidosis
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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