TreeWAS – Variant ID: rs6591182

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.164	0.836	0.000
I25 Chronic ischaemic heart disease	0.139	0.861	0.000
I25.2 Old myocardial infarction	0.136	0.864	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.116	0.884	0.000
I25.4 Coronary artery aneurysm	0.109	0.891	0.000
I25.6 Silent myocardial ischaemia	0.107	0.893	0.000
I25.3 Aneurysm of heart	0.105	0.895	0.000
I25.5 Ischaemic cardiomyopathy	0.084	0.916	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.080	0.920	0.000
R94.3 Abnormal results of cardiovascular function studies	0.067	0.933	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.065	0.935	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.968	0.032
L43.9 Lichen planus, unspecified	0.030	0.970	0.000
N40 Hyperplasia of prostate	0.025	0.975	0.000
L43 Lichen planus	0.022	0.977	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.979	0.021
L43.8 Other lichen planus	0.020	0.980	0.000
L43.0 Hypertrophic lichen planus	0.019	0.981	0.000
I20-I25 Ischaemic heart diseases	0.017	0.983	0.000
L43.3 Subacute (active) lichen planus	0.016	0.984	0.000
L43.2 Lichenoid drug reaction	0.016	0.984	0.000
L43.1 Bullous lichen planus	0.016	0.984	0.000
M25.50 Pain in joint (Multiple sites)	0.000	0.985	0.015
R94 Abnormal results of function studies	0.015	0.985	0.000
I23 Certain current complications following acute myocardial infarction	0.014	0.986	0.000
H40.1 Primary open-angle glaucoma	0.013	0.987	0.000
I23.8 Other current complications following acute myocardial infarction	0.013	0.987	0.000
I20.1 Angina pectoris with documented spasm	0.012	0.988	0.000
R10.2 Pelvic and perineal pain	0.000	0.988	0.012
R94.8 Abnormal results of function studies of other organs and systems	0.012	0.988	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.989	0.011
R94.7 Abnormal results of other endocrine function studies	0.011	0.989	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.011	0.989	0.000
I20 Angina pectoris	0.011	0.989	0.000
I22 Subsequent myocardial infarction	0.011	0.989	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.010	0.989	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.010	0.989	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.010	0.989	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.010	0.989	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.010	0.989	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.010	0.989	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.010	0.989	0.000
R94.6 Abnormal results of thyroid function studies	0.011	0.989	0.000
R94.2 Abnormal results of pulmonary function studies	0.010	0.990	0.000
R94.4 Abnormal results of kidney function studies	0.010	0.990	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.010	0.990	0.000
D13.1 Stomach	0.000	0.990	0.010
R94.0 Abnormal results of function studies of central nervous system	0.009	0.991	0.000
H40.8 Other glaucoma	0.009	0.991	0.000
C43.5 Malignant melanoma of trunk	0.000	0.991	0.009
C43 Malignant melanoma of skin	0.000	0.991	0.009
H40 Glaucoma	0.009	0.991	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.992	0.008
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.000	0.992	0.008
H40.9 Glaucoma, unspecified	0.008	0.992	0.000
I24 Other acute ischaemic heart diseases	0.008	0.992	0.000
I22.8 Subsequent myocardial infarction of other sites	0.008	0.992	0.000
D13.3 Other and unspecified parts of small intestine	0.000	0.993	0.007
D68.2 Hereditary deficiency of other clotting factors	0.007	0.993	0.000
H40.4 Glaucoma secondary to eye inflammation	0.007	0.993	0.000
D13.4 Liver	0.000	0.993	0.007
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.007	0.993	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.993	0.007
C43.0 Malignant melanoma of lip	0.000	0.993	0.007
H40.6 Glaucoma secondary to drugs	0.007	0.993	0.000
D13.5 Extrahepatic bile ducts	0.000	0.993	0.007
I24.1 Dressler's syndrome	0.007	0.993	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.007	0.993	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.006	0.994	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.006	0.994	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.000	0.994	0.006
D13.7 Endocrine pancreas	0.000	0.994	0.006
D12.4 Descending colon	0.000	0.994	0.006
D13.0 Oesophagus	0.000	0.994	0.006
D13.6 Pancreas	0.000	0.994	0.006
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.994	0.006
D13.9 Ill-defined sites within the digestive system	0.000	0.994	0.006
K60.2 Anal fissure, unspecified	0.000	0.994	0.006
H40.3 Glaucoma secondary to eye trauma	0.006	0.994	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.994	0.006
S01.1 Open wound of eyelid and periocular area	0.006	0.994	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.994	0.005
I24.8 Other forms of acute ischaemic heart disease	0.006	0.994	0.000
D13.2 Duodenum	0.000	0.995	0.005
H40.5 Glaucoma secondary to other eye disorders	0.005	0.995	0.000
N97.9 Female infertility, unspecified	0.005	0.995	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.005	0.995	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.005	0.995	0.000
Y84.6 Urinary catheterisation	0.005	0.995	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.005	0.995	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.995	0.005
G57.1 Meralgia paraesthetica	0.005	0.995	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.005	0.995	0.000
H57.8 Other specified disorders of eye and adnexa	0.000	0.995	0.005
I21.4 Acute subendocardial myocardial infarction	0.005	0.995	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.004	0.996	0.000
Y84.8 Other medical procedures	0.004	0.996	0.000
I21 Acute myocardial infarction	0.004	0.996	0.000
R90.0 Intracranial space-occupying lesion	0.004	0.996	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
I20.8 Other forms of angina pectoris	0.004	0.996	0.000
Y84.4 Aspiration of fluid	0.004	0.996	0.000
D41.0 Kidney	0.004	0.996	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.004	0.996	0.000
I20.9 Angina pectoris, unspecified	0.004	0.996	0.000
K14.8 Other diseases of tongue	0.000	0.996	0.004
Y84.9 Medical procedure, unspecified	0.004	0.996	0.000
Y84.1 Kidney dialysis	0.004	0.996	0.000
L40-L45 Papulosquamous disorders	0.003	0.996	0.000
D22.0 Melanocytic naevi of lip	0.004	0.996	0.000
F52.2 Failure of genital response	0.000	0.996	0.004
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.996	0.004
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
H40-H42 Glaucoma	0.004	0.996	0.000
L40.0 Psoriasis vulgaris	0.000	0.996	0.004
H80.9 Otosclerosis, unspecified	0.004	0.996	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.004	0.996	0.000
R01.1 Cardiac murmur, unspecified	0.003	0.997	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.003	0.997	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.997	0.003
I82.8 Embolism and thrombosis of other specified veins	0.003	0.997	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.003	0.997	0.000
N97.8 Female infertility of other origin	0.003	0.997	0.000
Y84.3 Shock therapy	0.003	0.997	0.000
N97 Female infertility	0.003	0.997	0.000
I49.3 Ventricular premature depolarisation	0.003	0.997	0.000
Y84.7 Blood-sampling	0.003	0.997	0.000
Y84.5 Insertion of gastric or duodenal sound	0.003	0.997	0.000
K72.0 Acute and subacute hepatic failure	0.000	0.997	0.003
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.997	0.003
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.003	0.997	0.000
O46.9 Antepartum haemorrhage, unspecified	0.000	0.997	0.003
D68 Other coagulation defects	0.003	0.997	0.000
L44 Other papulosquamous disorders	0.003	0.997	0.000
L41 Parapsoriasis	0.003	0.997	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
M16.9 Coxarthrosis, unspecified	0.003	0.997	0.000
D68.5 Primary Thrombophilia	0.003	0.997	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
D68.4 Acquired coagulation factor deficiency	0.003	0.997	0.000
F52.0 Lack or loss of sexual desire	0.000	0.997	0.003
H35.7 Separation of retinal layers	0.000	0.997	0.003
H42 Glaucoma in diseases classified elsewhere	0.003	0.997	0.000
K60.3 Anal fistula	0.000	0.997	0.003
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.003	0.997	0.000
F50.0 Anorexia nervosa	0.000	0.997	0.003
F50 Eating disorders	0.000	0.997	0.003
N97.0 Female infertility associated with anovulation	0.003	0.997	0.000
L42 Pityriasis rosea	0.002	0.997	0.000
D68.8 Other specified coagulation defects	0.003	0.997	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.000	0.997	0.003
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
N97.3 Female infertility of cervical origin	0.003	0.997	0.000
N97.2 Female infertility of uterine origin	0.003	0.997	0.000
N97.4 Female infertility associated with male factors	0.002	0.997	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.997	0.003
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.003	0.997	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.997	0.002
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.997	0.002
F52.7 Excessive sexual drive	0.000	0.997	0.002
F52.6 Nonorganic dyspareunia	0.000	0.997	0.002
F52.5 Nonorganic vaginismus	0.000	0.997	0.002
F52.4 Premature ejaculation	0.000	0.997	0.002
F52.3 Orgasmic dysfunction	0.000	0.997	0.002
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.997	0.002
F50.2 Bulimia nervosa	0.000	0.997	0.002
L44.0 Pityriasis rubra pilaris	0.002	0.997	0.000
L44.9 Papulosquamous disorder, unspecified	0.002	0.998	0.000
L44.8 Other specified papulosquamous disorders	0.002	0.998	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.002	0.998	0.000
L44.3 Lichen ruber moniliformis	0.002	0.998	0.000
L44.2 Lichen striatus	0.002	0.998	0.000
L44.1 Lichen nitidus	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
F50.9 Eating disorder, unspecified	0.000	0.998	0.002
O47.9 False labour, unspecified	0.002	0.998	0.000
D41.4 Bladder	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
L41.9 Parapsoriasis, unspecified	0.002	0.998	0.000
L41.8 Other parapsoriasis	0.002	0.998	0.000
L41.5 Retiform parapsoriasis	0.002	0.998	0.000
L41.4 Large plaque parapsoriasis	0.002	0.998	0.000
L41.3 Small plaque parapsoriasis	0.002	0.998	0.000
L41.2 Lymphomatoid papulosis	0.002	0.998	0.000
L41.1 Pityriasis lichenoides chronica	0.002	0.998	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.002	0.998	0.000
N97.1 Female infertility of tubal origin	0.002	0.998	0.000
H80 Otosclerosis	0.002	0.998	0.000
C84.5 Other and unspecified T-cell lymphomas	0.000	0.998	0.002
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.998	0.002
H42.8 Glaucoma in other diseases classified elsewhere	0.002	0.998	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.998	0.002
D41.2 Ureter	0.002	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.002	0.998	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.000	0.998	0.002
H31.0 Chorioretinal scars	0.002	0.998	0.000
H57.0 Anomalies of pupillary function	0.000	0.998	0.002
H57 Other disorders of eye and adnexa	0.000	0.998	0.002
F50.8 Other eating disorders	0.000	0.998	0.002
F50.5 Vomiting associated with other psychological disturbances	0.000	0.998	0.002
F50.4 Overeating associated with other psychological disturbances	0.000	0.998	0.002
F50.3 Atypical bulimia nervosa	0.000	0.998	0.002
F50.1 Atypical anorexia nervosa	0.000	0.998	0.002
Z54.0 Convalescence following surgery	0.002	0.998	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.998	0.002
J32.9 Chronic sinusitis, unspecified	0.002	0.998	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.002	0.998	0.000
C84.4 Peripheral T-cell lymphoma	0.000	0.998	0.002
N30.0 Acute cystitis	0.000	0.998	0.002
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
H80.8 Other otosclerosis	0.002	0.998	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.002	0.998	0.000
I82 Other venous embolism and thrombosis	0.002	0.998	0.000
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
L40 Psoriasis	0.000	0.998	0.002
R70.1 Abnormal plasma viscosity	0.000	0.998	0.002
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.998	0.002
I21.0 Acute transmural myocardial infarction of anterior wall	0.002	0.998	0.000
M25.76 Osteophyte (Lower leg)	0.002	0.998	0.000
I82.3 Embolism and thrombosis of renal vein	0.002	0.998	0.000
D41.1 Renal pelvis	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
H80.2 Cochlear otosclerosis	0.002	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.002	0.998	0.000
L40.8 Other psoriasis	0.000	0.998	0.002
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
G70.0 Myasthenia gravis	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
I12.9 Hypertensive renal disease without renal failure	0.002	0.998	0.000
Y83.9 Surgical procedure, unspecified	0.000	0.998	0.002
C84.0 Mycosis fungoides	0.000	0.998	0.002
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.998	0.002
K72.1 Chronic hepatic failure	0.000	0.998	0.002
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.998	0.002
V18 Pedal cyclist injured in noncollision transport accident	0.002	0.998	0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.000	0.998	0.002
F55 Abuse of non-dependence-producing substances	0.000	0.998	0.002
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.000	0.998	0.002
H81.1 Benign paroxysmal vertigo	0.002	0.998	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.998	0.002
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.998	0.002
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.998	0.002
C84.3 Lymphoepithelioid lymphoma	0.000	0.998	0.002
C84.2 T-zone lymphoma	0.000	0.998	0.002
C84.1 Sezary's diease	0.000	0.998	0.002
I82.2 Embolism and thrombosis of vena cava	0.002	0.998	0.000
K72 Hepatic failure, not elsewhere classified	0.000	0.998	0.002
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
I82.0 Budd-Chiari syndrome	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.998	0.002
K60 Fissure and fistula of anal and rectal regions	0.000	0.998	0.002
H60.1 Cellulitis of external ear	0.000	0.998	0.002
I82.1 Thrombophlebitis migrans	0.002	0.998	0.000
L40.2 Acrodermatitis continua	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R80 Isolated proteinuria	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
D48.6 Breast	0.000	0.998	0.002
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.998	0.002
I82.9 Embolism and thrombosis of unspecified vein	0.002	0.998	0.000
L40.5 Arthropathic psoriasis	0.000	0.998	0.002
L40.4 Guttate psoriasis	0.000	0.998	0.002
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.998	0.002
F51 Nonorganic sleep disorders	0.000	0.998	0.002
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.002	0.998	0.000
Z54.4 Convalescence following treatment of fracture	0.002	0.998	0.000
Z60.2 Living alone	0.000	0.998	0.002
F53.9 Puerperal mental disorder, unspecified	0.000	0.998	0.001
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.998	0.001
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.998	0.001
N73.6 Female pelvic peritoneal adhesions	0.000	0.998	0.002
V18.3 Person injured while boarding or alighting	0.002	0.998	0.000
M35.3 Polymyalgia rheumatica	0.000	0.998	0.002
V18.9 Unspecified pedal cyclist injured in traffic accident	0.002	0.998	0.000
V18.4 Driver injured in traffic accident	0.002	0.998	0.000
V18.5 Passenger injured in traffic accident	0.002	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.998	0.002
L40.1 Generalised pustular psoriasis	0.000	0.998	0.001
R93.6 Abnormal findings on diagnostic imaging of limbs	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
L93.0 Discoid lupus erythematosus	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.001	0.998	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.998	0.002
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
F60.6 Anxious [avoidant] personality disorder	0.002	0.998	0.000
I12.0 Hypertensive renal disease with renal failure	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.001	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.001	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.001	0.998	0.000
T45.4 Iron and its compounds	0.001	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.001	0.998	0.000
V18.1 Passenger injured in nontraffic accident	0.001	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
I12 Hypertensive renal disease	0.002	0.998	0.000
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
H16.9 Keratitis, unspecified	0.000	0.998	0.002
V18.0 Driver injured in nontraffic accident	0.002	0.998	0.000
F51.5 Nightmares	0.000	0.998	0.001
F60.0 Paranoid personality disorder	0.001	0.998	0.000
I20.0 Unstable angina	0.002	0.998	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.998	0.000
M13.98 Arthritis, unspecified (Other)	0.000	0.998	0.002
F51.9 Nonorganic sleep disorder, unspecified	0.000	0.998	0.001
F51.8 Other nonorganic sleep disorders	0.000	0.998	0.001
F51.4 Sleep terrors [night terrors]	0.000	0.998	0.001
F51.2 Nonorganic disorder of the sleep-wake schedule	0.000	0.998	0.001
F51.1 Nonorganic hypersomnia	0.000	0.998	0.001
I47.2 Ventricular tachycardia	0.002	0.998	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.998	0.002
O41.0 Oligohydramnios	0.000	0.998	0.001
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.001	0.998	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.001	0.998	0.000
K60.5 Anorectal fistula	0.000	0.998	0.001
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.001	0.999	0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.001	0.999	0.000
H50.4 Other and unspecified heterotropia	0.001	0.999	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.001	0.999	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
K72.9 Hepatic failure, unspecified	0.000	0.999	0.001
N36.8 Other specified disorders of urethra	0.001	0.999	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.999	0.001
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
R23.4 Changes in skin texture	0.001	0.999	0.000
L73.8 Other specified follicular disorders	0.000	0.999	0.001
K37 Unspecified appendicitis	0.000	0.999	0.001
L94.2 Calcinosis cutis	0.001	0.999	0.000
S01.5 Open wound of lip and oral cavity	0.001	0.999	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.001	0.999	0.000
F51.0 Nonorganic insomnia	0.000	0.999	0.001
F60.4 Histrionic personality disorder	0.001	0.999	0.000
F60.1 Schizoid personality disorder	0.001	0.999	0.000
G50.0 Trigeminal neuralgia	0.000	0.999	0.001
I21.2 Acute transmural myocardial infarction of other sites	0.001	0.999	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.001	0.999	0.000
F51.3 Sleepwalking [somnambulism]	0.000	0.999	0.001
I15.1 Hypertension secondary to other renal disorders	0.001	0.999	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.001	0.999	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.001	0.999	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
H57.1 Ocular pain	0.000	0.999	0.001
M62.8 Other specified disorders of muscle	0.001	0.999	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.999	0.001
Z54 Convalescence	0.001	0.999	0.000
D68.9 Coagulation defect, unspecified	0.001	0.999	0.000
H50.2 Vertical strabismus	0.001	0.999	0.000
R22.0 Localised swelling, mass and lump, head	0.000	0.999	0.001
F60.2 Dissocial personality disorder	0.001	0.999	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.999	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.999	0.001
B00.9 Herpesviral infection, unspecified	0.001	0.999	0.000
C16.0 Cardia	0.001	0.999	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.001	0.999	0.000
H60.9 Otitis externa, unspecified	0.000	0.999	0.001
Y91.9 Alcohol involvement, not otherwise specified	0.001	0.999	0.000
E11.5 With peripheral circulatory complications	0.001	0.999	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.001	0.999	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.999	0.001
H11.0 Pterygium	0.001	0.999	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.001	0.999	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.999	0.001
Z49.1 Extracorporeal dialysis	0.001	0.999	0.000
M62 Other disorders of muscle	0.001	0.999	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.001	0.999	0.000
D35.1 Parathyroid gland	0.001	0.999	0.000
E11.2 With renal complications	0.001	0.999	0.000
F60.8 Other specific personality disorders	0.001	0.999	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.999	0.001
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
L40.9 Psoriasis, unspecified	0.000	0.999	0.001
H50 Other strabismus	0.001	0.999	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.001	0.999	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000
C85.0 Lymphosarcoma	0.000	0.999	0.001
F60.7 Dependent personality disorder	0.001	0.999	0.000
F60.5 Anankastic personality disorder	0.001	0.999	0.000
N05.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
Z54.7 Convalescence following combined treatment	0.001	0.999	0.000
Z54.3 Convalescence following psychotherapy	0.001	0.999	0.000
Z54.2 Convalescence following chemotherapy	0.001	0.999	0.000
Z54.1 Convalescence following radiotherapy	0.001	0.999	0.000
J14 Pneumonia due to Haemophilus influenzae	0.001	0.999	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.999	0.001
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.001	0.999	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.001	0.999	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.001	0.999	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.001	0.999	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.001	0.999	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.001	0.999	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.001	0.999	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.001	0.999	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
H60.4 Cholesteatoma of external ear	0.000	0.999	0.001
I86.8 Varicose veins of other specified sites	0.001	0.999	0.000
Z54.9 Convalescence following unspecified treatment	0.001	0.999	0.000
M90.80 Osteopathy in other diseases classified elsewhere (Multiple sites)	0.001	0.999	0.000
H16.0 Corneal ulcer	0.000	0.999	0.001
H60.0 Abscess of external ear	0.000	0.999	0.001
L94.0 Localised scleroderma [morphea]	0.001	0.999	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.001	0.999	0.000
M62.84 Other specified disorders of muscle (Hand)	0.001	0.999	0.000
S82.10 Fracture of upper end of tibia (closed)	0.001	0.999	0.000
G70.8 Other specified myoneural disorders	0.001	0.999	0.000
H50.6 Mechanical strabismus	0.001	0.999	0.000
H51.2 Internuclear ophthalmoplegia	0.001	0.999	0.000
K82.3 Fistula of gallbladder	0.000	0.999	0.001
M62.6 Muscle strain	0.001	0.999	0.000
M62.0 Diastasis of muscle	0.001	0.999	0.000
Q78.0 Osteogenesis imperfecta	0.001	0.999	0.000
Z94.1 Heart transplant status	0.001	0.999	0.000
G70 Myasthenia gravis and other myoneural disorders	0.001	0.999	0.000
H49 Paralytic strabismus	0.001	0.999	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.999	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.999	0.001
D43.2 Brain, unspecified	0.000	0.999	0.001
H50.3 Intermittent heterotropia	0.001	0.999	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.001	0.999	0.000
K60.4 Rectal fistula	0.000	0.999	0.001
M62.4 Contracture of muscle	0.001	0.999	0.000
M62.3 Immobility syndrome (paraplegic)	0.001	0.999	0.000
M62.2 Ischaemic infarction of muscle	0.001	0.999	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.001	0.999	0.000
V17.0 Driver injured in nontraffic accident	0.001	0.999	0.000
Z49.2 Other dialysis	0.001	0.999	0.000
H60 Otitis externa	0.000	0.999	0.001
D04.6 Skin of upper limb, including shoulder	0.000	0.999	0.001
G70.9 Myoneural disorder, unspecified	0.001	0.999	0.000
H16.2 Keratoconjunctivitis	0.000	0.999	0.001
I15.0 Renovascular hypertension	0.001	0.999	0.000
I21.9 Acute myocardial infarction, unspecified	0.001	0.999	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.001	0.999	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.999	0.001
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.999	0.001
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.001	0.999	0.000
S89 Other and unspecified injuries of lower leg	0.001	0.999	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.001	0.999	0.000
G50.1 Atypical facial pain	0.000	0.999	0.001
H60.2 Malignant otitis externa	0.000	0.999	0.001
N05.8 Other	0.001	0.999	0.000
V17.4 Driver injured in traffic accident	0.001	0.999	0.000
V17 Pedal cyclist injured in collision with fixed or stationary object	0.001	0.999	0.000
M62.66 Muscle strain (Lower leg)	0.001	0.999	0.000
M90.61 Osteitis deformans in neoplastic disease (Shoulder region)	0.001	0.999	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.999	0.001
F31.0 Bipolar affective disorder, current episode hypomanic	0.001	0.999	0.000
G70.2 Congenital and developmental myasthenia	0.001	0.999	0.000
G70.1 Toxic myoneural disorders	0.001	0.999	0.000
H49.3 Total (external) ophthalmoplegia	0.001	0.999	0.000
H50.8 Other specified strabismus	0.001	0.999	0.000
I61.8 Other intracerebral haemorrhage	0.001	0.999	0.000
M62.9 Disorder of muscle, unspecified	0.001	0.999	0.000
M90.6 Osteitis deformans in neoplastic disease	0.001	0.999	0.000
N05.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
N76.8 Other specified inflammation of vagina and vulva	0.001	0.999	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.001	0.999	0.000
M90 Osteopathies in diseases classified elsewhere	0.001	0.999	0.000
N05 Unspecified nephritic syndrome	0.001	0.999	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.001	0.999	0.000
M62.08 Diastasis of muscle (Other)	0.001	0.999	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.001	0.999	0.000
M62.06 Diastasis of muscle (Lower leg)	0.001	0.999	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.04 Diastasis of muscle (Hand)	0.001	0.999	0.000
M62.03 Diastasis of muscle (Forearm)	0.001	0.999	0.000
M62.02 Diastasis of muscle (Upper arm)	0.001	0.999	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.001	0.999	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations