TreeWAS – Variant ID: rs6598541

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N20.0 Calculus of kidney	0.022	0.978	0.000
N20.2 Calculus of kidney with calculus of ureter	0.021	0.979	0.000
N20 Calculus of kidney and ureter	0.019	0.981	0.000
N20.9 Urinary calculus, unspecified	0.016	0.984	0.000
O80.0 Spontaneous vertex delivery	0.012	0.988	0.000
I45.1 Other and unspecified right bundle-branch block	0.010	0.990	0.000
H53.0 Amblyopia ex anopsia	0.000	0.991	0.009
N20.1 Calculus of ureter	0.009	0.991	0.000
G56.8 Other mononeuropathies of upper limb	0.000	0.991	0.009
O80.8 Other single spontaneous delivery	0.007	0.993	0.000
O80 Single spontaneous delivery	0.006	0.993	0.000
D41.0 Kidney	0.000	0.993	0.007
H40.2 Primary angle-closure glaucoma	0.000	0.994	0.005
D41.4 Bladder	0.000	0.995	0.005
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.995	0.005
O80.1 Spontaneous breech delivery	0.005	0.995	0.000
X49.9 Unspecified place	0.000	0.995	0.005
D41.1 Renal pelvis	0.000	0.995	0.005
S91.0 Open wound of ankle	0.004	0.996	0.000
S64.4 Injury of digital nerve of other finger	0.004	0.996	0.000
L28.0 Lichen simplex chronicus	0.000	0.996	0.004
M25.47 Effusion of joint (Ankle and foot)	0.000	0.996	0.004
S91.3 Open wound of other parts of foot	0.004	0.996	0.000
D41.9 Urinary organ, unspecified	0.000	0.996	0.004
D41.7 Other urinary organs	0.000	0.996	0.004
D41.3 Urethra	0.000	0.996	0.004
Z00.0 General medical examination	0.004	0.996	0.000
S91 Open wound of ankle and foot	0.004	0.996	0.000
Z01.4 Gynaecological examination (general)(routine)	0.000	0.996	0.004
K12.1 Other forms of stomatitis	0.000	0.996	0.004
D41.2 Ureter	0.000	0.996	0.003
E83.3 Disorders of phosphorus metabolism	0.000	0.996	0.004
S91.1 Open wound of toe(s) without damage to nail	0.003	0.997	0.000
N20-N23 Urolithiasis	0.003	0.997	0.000
D50.8 Other iron deficiency anaemias	0.000	0.997	0.003
S91.2 Open wound of toe(s) with damage to nail	0.003	0.997	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.997	0.003
S91.7 Multiple open wounds of ankle and foot	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.997	0.003
C67.3 Anterior wall of bladder	0.000	0.997	0.003
O62.2 Other uterine inertia	0.000	0.997	0.003
S43.1 Dislocation of acromioclavicular joint	0.000	0.997	0.003
G71.1 Myotonic disorders	0.000	0.997	0.003
Z00.4 General psychiatric examination, not elsewhere classified	0.003	0.997	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.003	0.997	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.997	0.003
K22.9 Disease of oesophagus, unspecified	0.000	0.997	0.003
H40.0 Glaucoma suspect	0.003	0.997	0.000
M41.9 Scoliosis, unspecified	0.000	0.997	0.003
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.000	0.997	0.003
S82.30 Fracture of lower end of tibia (closed)	0.000	0.997	0.003
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.997	0.003
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.997	0.003
S13.1 Dislocation of cervical vertebra	0.000	0.997	0.003
N22 Calculus of urinary tract in diseases classified elsewhere	0.003	0.997	0.000
O80.9 Single spontaneous delivery, unspecified	0.000	0.997	0.002
H58.8 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
J35.0 Chronic tonsillitis	0.000	0.997	0.003
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.000	0.997	0.003
C67.8 Overlapping lesion of bladder	0.000	0.997	0.003
M25.42 Effusion of joint (Upper arm)	0.000	0.997	0.002
R86.8 Other abnormal findings	0.000	0.997	0.003
S81.9 Open wound of lower leg, part unspecified	0.003	0.997	0.000
G71 Primary disorders of muscles	0.000	0.997	0.002
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.998	0.002
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M25.4 Effusion of joint	0.000	0.998	0.002
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.998	0.002
C67.4 Posterior wall of bladder	0.000	0.998	0.002
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.998	0.002
N21 Calculus of lower urinary tract	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.998	0.002
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
G71.0 Muscular dystrophy	0.000	0.998	0.002
R86.9 Unspecified abnormal finding	0.000	0.998	0.002
S31.1 Open wound of abdominal wall	0.000	0.998	0.002
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.998	0.002
M25.43 Effusion of joint (Forearm)	0.000	0.998	0.002
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.002	0.998	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.002	0.998	0.000
N21.1 Calculus in urethra	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.000	0.998	0.002
I61.3 Intracerebral haemorrhage in brain stem	0.002	0.998	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.002	0.998	0.000
C67 Malignant neoplasm of bladder	0.000	0.998	0.002
Y84.8 Other medical procedures	0.000	0.998	0.002
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.998	0.002
M25.53 Pain in joint (Forearm)	0.000	0.998	0.002
X49.4 Street and highway	0.000	0.998	0.002
X49.0 Home	0.000	0.998	0.002
X49.8 Other specified place	0.000	0.998	0.002
X49.7 Farm	0.000	0.998	0.002
X49.3 Sports and athletics area	0.000	0.998	0.002
X49.2 School, other institution and public administrative area	0.000	0.998	0.002
X49.1 Residential institution	0.000	0.998	0.002
E24 Cushing's syndrome	0.000	0.998	0.002
D37.9 Digestive organ, unspecified	0.000	0.998	0.002
H53.9 Visual disturbance, unspecified	0.002	0.998	0.000
I61.8 Other intracerebral haemorrhage	0.002	0.998	0.000
C67.1 Dome of bladder	0.000	0.998	0.002
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
Z48.9 Surgical follow-up care, unspecified	0.000	0.998	0.002
G71.9 Primary disorder of muscle, unspecified	0.000	0.998	0.002
G71.8 Other primary disorders of muscles	0.000	0.998	0.002
G71.2 Congenital myopathies	0.000	0.998	0.002
N21.9 Calculus of lower urinary tract, unspecified	0.002	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
X49.5 Trade and service area	0.000	0.998	0.002
M25.44 Effusion of joint (Hand)	0.000	0.998	0.002
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.002
S11.9 Open wound of neck, part unspecified	0.000	0.998	0.002
Z00.3 Examination for adolescent development state	0.002	0.998	0.000
Z00.2 Examination for period of rapid growth in childhood	0.002	0.998	0.000
Z00.1 Routine child health examination	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.002	0.998	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.002	0.998	0.000
O62.0 Primary inadequate contractions	0.000	0.998	0.002
Z00.5 Examination of potential donor of organ and tissue	0.002	0.998	0.000
M25.49 Effusion of joint (Site unspecified)	0.000	0.998	0.002
M25.48 Effusion of joint (Other)	0.000	0.998	0.002
M25.41 Effusion of joint (Shoulder region)	0.000	0.998	0.002
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
X49.6 Industrial and construction area	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.998	0.002
R86 Abnormal findings in specimens from male genital organs	0.000	0.998	0.002
D37.1 Stomach	0.000	0.998	0.002
I61.4 Intracerebral haemorrhage in cerebellum	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
Z00.8 Other general examinations	0.002	0.998	0.000
M10.99 Gout, unspecified (Site unspecified)	0.000	0.998	0.002
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.998	0.002
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.998	0.002
M00.9 Pyogenic arthritis, unspecified	0.002	0.998	0.000
I61 Intracerebral haemorrhage	0.002	0.998	0.000
K11.2 Sialoadenitis	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.002	0.998	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.002	0.998	0.000
C74.1 Medulla of adrenal gland	0.002	0.998	0.000
C67.7 Urachus	0.000	0.998	0.002
D37.2 Small intestine	0.000	0.998	0.002
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.998	0.002
M00.94 Pyogenic arthritis, unspecified (Hand)	0.002	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.002	0.998	0.000
X49.09 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Home; During unspecified activity	0.000	0.998	0.002
X49.48 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Street and highway;While engaged in other specified activities	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.002
E24.1 Nelson's syndrome	0.000	0.998	0.002
M10.9 Gout, unspecified	0.000	0.998	0.002
Q15.0 Congenital glaucoma	0.002	0.998	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.998	0.002
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.000	0.998	0.002
D05.1 Intraductal carcinoma in situ	0.000	0.998	0.002
D37.3 Appendix	0.000	0.998	0.002
E24.0 Pituitary-dependent Cushing's disease	0.000	0.998	0.002
N21.8 Other lower urinary tract calculus	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
M10.96 Gout, unspecified (Lower leg)	0.000	0.998	0.002
C43.5 Malignant melanoma of trunk	0.000	0.998	0.002
D47.2 Monoclonal gammopathy	0.000	0.998	0.002
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.002	0.998	0.000
S11 Open wound of neck	0.000	0.998	0.002
R86.7 Abnormal histological findings	0.000	0.998	0.002
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.000	0.998	0.002
M72.2 Plantar fascial fibromatosis	0.000	0.998	0.002
R86.5 Abnormal microbiological findings	0.000	0.998	0.002
R86.0 Abnormal level of enzymes	0.000	0.998	0.002
S14.1 Other and unspecified injuries of cervical spinal cord	0.000	0.998	0.002
M72.29 Plantar fascial fibromatosis-Site unspec	0.000	0.998	0.002
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.998	0.002
R09.1 Pleurisy	0.000	0.998	0.002
O62 Abnormalities of forces of labour	0.000	0.998	0.002
S14 Injury of nerves and spinal cord at neck level	0.000	0.998	0.002
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M10.93 Gout, unspecified (Forearm)	0.000	0.998	0.002
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
R86.4 Abnormal immunological findings	0.000	0.998	0.002
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.998	0.002
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.998	0.002
S11.7 Multiple open wounds of neck	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
M10.09 Idiopathic gout (Site unspecified)	0.000	0.998	0.002
M10.06 Idiopathic gout (Lower leg)	0.000	0.998	0.002
S42.00 Fracture of clavicle (closed)	0.002	0.998	0.000
D31.3 Choroid	0.000	0.998	0.002
M10.0 Idiopathic gout	0.000	0.998	0.002
S14.3 Injury of brachial plexus	0.000	0.998	0.002
X58.9 Unspecified place	0.002	0.998	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.000	0.998	0.002
D38.0 Larynx	0.000	0.998	0.002
M00.98 Pyogenic arthritis, unspecified (Other)	0.001	0.998	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.001	0.998	0.000
B02.2 Zoster with other nervous system involvement	0.002	0.998	0.000
J35.2 Hypertrophy of adenoids	0.000	0.998	0.002
C74 Malignant neoplasm of adrenal gland	0.002	0.998	0.000
M10.92 Gout, unspecified (Upper arm)	0.000	0.998	0.002
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
C67.0 Trigone of bladder	0.000	0.998	0.001
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
I42.6 Alcoholic cardiomyopathy	0.002	0.998	0.000
S42.0 Fracture of clavicle	0.002	0.998	0.000
C73 Malignant neoplasm of thyroid gland	0.002	0.998	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.001	0.998	0.000
O62.1 Secondary uterine inertia	0.000	0.998	0.002
R86.1 Abnormal level of hormones	0.000	0.998	0.001
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.998	0.000
B99 Other and unspecified infectious diseases	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.998	0.002
M10.98 Gout, unspecified (Other)	0.000	0.998	0.001
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M10.91 Gout, unspecified (Shoulder region)	0.000	0.998	0.001
C74.9 Adrenal gland, unspecified	0.001	0.998	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.998	0.001
Q12.0 Congenital cataract	0.002	0.998	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.001	0.998	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.000	0.998	0.001
S11.1 Open wound involving thyroid gland	0.000	0.998	0.001
S11.0 Open wound involving larynx and trachea	0.000	0.998	0.001
X45.0 Home	0.000	0.998	0.001
S42 Fracture of shoulder and upper arm	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.001	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.001	0.998	0.000
M72.28 Plantar fascial fibromatosis-Other	0.000	0.998	0.001
M72.26 Plantar fascial fibromatosis-Lower Leg	0.000	0.998	0.001
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh	0.000	0.998	0.001
M72.24 Plantar fascial fibromatosis-Hand	0.000	0.998	0.001
M72.23 Plantar fascial fibromatosis-Forearm	0.000	0.998	0.001
M72.22 Plantar fascial fibromatosis-Upper arm	0.000	0.998	0.001
M72.21 Plantar fascial fibromatosis-Shldr region	0.000	0.998	0.001
M72.20 Plantar fascial fibromatosis-Mult sites	0.000	0.998	0.001
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.998	0.002
R86.6 Abnormal cytological findings	0.000	0.998	0.001
S13.5 Sprain and strain of thyroid region	0.000	0.998	0.001
S13.3 Multiple dislocations of neck	0.000	0.998	0.001
S13.2 Dislocation of other and unspecified parts of neck	0.000	0.998	0.001
S13.0 Traumatic rupture of cervical intervertebral disk	0.000	0.998	0.001
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.001	0.998	0.000
M10.00 Idiopathic gout (Multiple sites)	0.000	0.998	0.001
S42.21 Fracture of upper end of humerus (open)	0.001	0.998	0.000
C74.0 Cortex of adrenal gland	0.001	0.998	0.000
D37.7 Other digestive organs	0.000	0.998	0.001
S93.4 Sprain and strain of ankle	0.001	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.998	0.000
L28 Lichen simplex chronicus and prurigo	0.000	0.998	0.001
S10-S19 Injuries to the neck	0.000	0.998	0.002
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.001	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.001	0.998	0.000
S14.6 Injury of other and unspecified nerves of neck	0.000	0.998	0.001
S14.5 Injury of cervical sympathetic nerves	0.000	0.998	0.001
S14.4 Injury of peripheral nerves of neck	0.000	0.998	0.001
S14.2 Injury of nerve root of cervical spine	0.000	0.998	0.001
S14.0 Concussion and oedema of cervical spinal cord	0.000	0.998	0.001
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.999	0.000
Q18 Other congenital malformations of face and neck	0.001	0.999	0.000
Q15 Other congenital malformations of eye	0.001	0.999	0.000
M10.08 Idiopathic gout (Other)	0.000	0.999	0.001
M10.05 Idiopathic gout (Pelvic region and thigh)	0.000	0.999	0.001
M10.03 Idiopathic gout (Forearm)	0.000	0.999	0.001
M10.01 Idiopathic gout (Shoulder region)	0.000	0.999	0.001
G93.4 Encephalopathy, unspecified	0.001	0.999	0.000
M10.04 Idiopathic gout (Hand)	0.000	0.999	0.001
M10.02 Idiopathic gout (Upper arm)	0.000	0.999	0.001
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.999	0.001
D37.5 Rectum	0.000	0.999	0.001
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.001	0.999	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.999	0.001
Q54.1 Hypospadias, penile	0.001	0.999	0.000
S42.3 Fracture of shaft of humerus	0.001	0.999	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.999	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.001	0.999	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.000	0.999	0.001
K31.9 Disease of stomach and duodenum, unspecified	0.000	0.999	0.001
S42.01 Fracture of clavicle (open)	0.001	0.999	0.000
B02.3 Zoster ocular disease	0.001	0.999	0.000
C50.1 Central portion of breast	0.000	0.999	0.001
O62.3 Precipitate labour	0.000	0.999	0.001
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.999	0.000
D38.6 Respiratory organ, unspecified	0.000	0.999	0.001
D38.4 Thymus	0.000	0.999	0.001
D38.3 Mediastinum	0.000	0.999	0.001
D38.2 Pleura	0.000	0.999	0.001
O62.8 Other abnormalities of forces of labour	0.000	0.999	0.001
S11.8 Open wound of other parts of neck	0.000	0.999	0.001
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.000	0.999	0.001
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
S97 Crushing injury of ankle and foot	0.001	0.999	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.999	0.001
M77.1 Lateral epicondylitis	0.000	0.999	0.001
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.999	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.999	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.999	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.999	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.999	0.000
S94.1 Injury of medial plantar nerve	0.001	0.999	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.999	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.999	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.999	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.999	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.999	0.000
S95.1 Injury of plantar artery of foot	0.001	0.999	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.999	0.000
S10 Superficial injury of neck	0.000	0.999	0.001
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.001	0.999	0.000
C67.5 Bladder neck	0.000	0.999	0.001
E22.1 Hyperprolactinaemia	0.000	0.999	0.001
S42.8 Fracture of other parts of shoulder and upper arm	0.001	0.999	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.999	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.999	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.999	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.999	0.000
Q12 Congenital lens malformations	0.001	0.999	0.000
S02.00 Fracture of vault of skull (closed)	0.001	0.999	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
D40.0 Prostate	0.000	0.999	0.001
F39 Unspecified mood [affective] disorder	0.000	0.999	0.001
S17 Crushing injury of neck	0.000	0.999	0.001
S15 Injury of blood vessels at neck level	0.000	0.999	0.001
S18 Traumatic amputation at neck level	0.000	0.999	0.001
S16 Injury of muscle and tendon at neck level	0.000	0.999	0.001
C67.6 Ureteric orifice	0.000	0.999	0.001
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.999	0.001
N28.8 Other specified disorders of kidney and ureter	0.001	0.999	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.999	0.001
Q15.9 Congenital malformation of eye, unspecified	0.001	0.999	0.000
Q15.8 Other specified congenital malformations of eye	0.001	0.999	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.001	0.999	0.000
Q18.8 Other specified congenital malformations of face and neck	0.001	0.999	0.000
Q18.7 Microcheilia	0.001	0.999	0.000
Q18.6 Macrocheilia	0.001	0.999	0.000
Q18.5 Microstomia	0.001	0.999	0.000
Q18.4 Macrostomia	0.001	0.999	0.000
Q18.3 Webbing of neck	0.001	0.999	0.000
Q18.2 Other branchial cleft malformations	0.001	0.999	0.000
S02.3 Fracture of orbital floor	0.001	0.999	0.000
S42.4 Fracture of lower end of humerus	0.001	0.999	0.000
S98.1 Traumatic amputation of one toe	0.001	0.999	0.000
X50.4 Street and highway	0.001	0.999	0.000
M10 Gout	0.000	0.999	0.001
M10.90 Gout, unspecified (Multiple sites)	0.000	0.999	0.001
N04.9 Unspecified	0.001	0.999	0.000
S10.1 Other and unspecified superficial injuries of throat	0.000	0.999	0.001
X45 Accidental poisoning by and exposure to alcohol	0.000	0.999	0.001
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.999	0.001
R20.2 Paraesthesia of skin	0.001	0.999	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.001	0.999	0.000
S10.8 Superficial injury of other parts of neck	0.000	0.999	0.001
S19.9 Unspecified injury of neck	0.000	0.999	0.001
S41.1 Open wound of upper arm	0.000	0.999	0.001
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.999	0.001
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.001	0.999	0.000
M41 Scoliosis	0.000	0.999	0.001
S19 Other and unspecified injuries of neck	0.000	0.999	0.001
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.999	0.001
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.999	0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.999	0.001
M10.3 Gout due to impairment of renal function	0.000	0.999	0.001
Z89.6 Acquired absence of leg above knee	0.000	0.999	0.001
M77.13 Lateral epicondylitis-Forearm	0.000	0.999	0.001
L28.2 Other prurigo	0.000	0.999	0.001
S10.7 Multiple superficial injuries of neck	0.000	0.999	0.001
S10.0 Contusion of throat	0.000	0.999	0.001
S97.0 Crushing injury of ankle	0.001	0.999	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.999	0.001
M00 Pyogenic arthritis	0.001	0.999	0.000
M10.39 Gout due to impairment of renal function (Site unspecified)	0.000	0.999	0.001
M77.19 Lateral epicondylitis (Site unspecified)	0.000	0.999	0.001
M77.18 Lateral epicondylitis-Other	0.000	0.999	0.001
M77.17 Lateral epicondylitis-Ankle/Foot	0.000	0.999	0.001
M77.16 Lateral epicondylitis (Lower leg)	0.000	0.999	0.001
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.000	0.999	0.001
M77.14 Lateral epicondylitis-Hand	0.000	0.999	0.001
M77.11 Lateral epicondylitis-Shldr region	0.000	0.999	0.001
M77.10 Lateral epicondylitis (Multiple sites)	0.000	0.999	0.001
S42.41 Fracture of lower end of humerus (open)	0.001	0.999	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.001	0.999	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.001	0.999	0.000
G82.1 Spastic paraplegia	0.001	0.999	0.000
J35.1 Hypertrophy of tonsils	0.000	0.999	0.001
M00.0 Staphylococcal arthritis and polyarthritis	0.001	0.999	0.000
M41.4 Neuromuscular scoliosis	0.000	0.999	0.001
Q12.9 Congenital lens malformation, unspecified	0.001	0.999	0.000
Q12.8 Other congenital lens malformations	0.001	0.999	0.000
Q12.4 Spherophakia	0.001	0.999	0.000
Q12.3 Congenital aphakia	0.001	0.999	0.000
Q12.2 Coloboma of lens	0.001	0.999	0.000
Q12.1 Congenital displaced lens	0.001	0.999	0.000
M00.06 Staphylococcal arthritis and polyarthritis (Lower leg)	0.001	0.999	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.999	0.001
S12.00 Fracture of first cervical vertebra (closed)	0.000	0.999	0.001
D37.6 Liver, gallbladder and bile ducts	0.000	0.999	0.001
D38.5 Other respiratory organs	0.000	0.999	0.001
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.001	0.999	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.999	0.001
O62.9 Abnormality of forces of labour, unspecified	0.000	0.999	0.001
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.999	0.001
S12.0 Fracture of first cervical vertebra	0.000	0.999	0.001
S15.9 Injury of unspecified blood vessel at neck level	0.000	0.999	0.001
S15.8 Injury of other blood vessels at neck level	0.000	0.999	0.001
S15.7 Injury of multiple blood vessels at neck level	0.000	0.999	0.001
S15.3 Injury of internal jugular vein	0.000	0.999	0.001
S15.2 Injury of external jugular vein	0.000	0.999	0.001
S15.1 Injury of vertebral artery	0.000	0.999	0.001
S15.0 Injury of carotid artery	0.000	0.999	0.001
S17.9 Crushing injury of neck, part unspecified	0.000	0.999	0.001
S17.8 Crushing injury of other parts of neck	0.000	0.999	0.001
S17.0 Crushing injury of larynx and traches	0.000	0.999	0.001
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.999	0.001
S12 Fracture of neck	0.000	0.999	0.001
M00.86 Arthritis and polyarthritis due to other specified bacterial agents (Lower leg)	0.001	0.999	0.000
M41.49 Neuromuscular scoliosis (Site unspecified)	0.000	0.999	0.001
S02.31 Fracture of orbital floor (open)	0.001	0.999	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.999	0.001
H11.3 Conjunctival haemorrhage	0.001	0.999	0.000
H92.0 Otalgia	0.000	0.999	0.001
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.999	0.001
M10.4 Other secondary gout	0.000	0.999	0.001
M10.2 Drug-induced gout	0.000	0.999	0.001
M10.1 Lead-induced gout	0.000	0.999	0.001
R27.8 Other and unspecified lack of coordination	0.001	0.999	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.001	0.999	0.000
S90 Superficial injury of ankle and foot	0.001	0.999	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.001	0.999	0.000
D40.9 Male genital organ, unspecified	0.000	0.999	0.001
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.001	0.999	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.001	0.999	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.001	0.999	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.001	0.999	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.001	0.999	0.000
M41.3 Thoracogenic scoliosis	0.000	0.999	0.001
M41.1 Juvenile idiopathic scoliosis	0.000	0.999	0.001
M41.0 Infantile idiopathic scoliosis	0.000	0.999	0.001
S19.7 Multiple injuries of neck	0.000	0.999	0.001
S97.1 Crushing injury of toe(s)	0.001	0.999	0.000
V49.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
X45.9 Unspecified place	0.000	0.999	0.001
X45.8 Other specified place	0.000	0.999	0.001
X45.7 Farm	0.000	0.999	0.001
X45.6 Industrial and construction area	0.000	0.999	0.001
X45.5 Trade and service area	0.000	0.999	0.001
X45.4 Street and highway	0.000	0.999	0.001
X45.3 Sports and athletics area	0.000	0.999	0.001
X45.2 School, other institution and public administrative area	0.000	0.999	0.001
X45.1 Residential institution	0.000	0.999	0.001
M10.38 Gout due to impairment of renal function (Other)	0.000	0.999	0.001
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.000	0.999	0.001
M10.36 Gout due to impairment of renal function (Lower leg)	0.000	0.999	0.001
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.000	0.999	0.001
M10.34 Gout due to impairment of renal function (Hand)	0.000	0.999	0.001
M10.33 Gout due to impairment of renal function (Forearm)	0.000	0.999	0.001
M10.32 Gout due to impairment of renal function (Upper arm)	0.000	0.999	0.001
M10.31 Gout due to impairment of renal function (Shoulder region)	0.000	0.999	0.001
M10.30 Gout due to impairment of renal function (Multiple sites)	0.000	0.999	0.001
D37.0 Lip, oral cavity and pharynx	0.000	0.999	0.001
D39.7 Other female genital organs	0.000	0.999	0.001
D40.1 Testis	0.000	0.999	0.001
D42.9 Meninges, unspecified	0.000	0.999	0.001
D42.1 Spinal meninges	0.000	0.999	0.001
D42.0 Cerebral meninges	0.000	0.999	0.001
G53.0 Postzoster neuralgia	0.001	0.999	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.001	0.999	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.001	0.999	0.000
M41.8 Other forms of scoliosis	0.000	0.999	0.001
M87.2 Osteonecrosis due to previous trauma	0.000	0.999	0.001
S90.1 Contusion of toe(s) without damage to nail	0.001	0.999	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.999	0.000
T14.0 Superficial injury of unspecified body region	0.000	0.999	0.001
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.001	0.999	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.999	0.000
M00.09 Staphylococcal arthritis and polyarthritis (Site unspecified)	0.001	0.999	0.000
M00.08 Staphylococcal arthritis and polyarthritis (Other)	0.001	0.999	0.000
M00.07 Staphylococcal arthritis and polyarthritis (Ankle and foot)	0.001	0.999	0.000
M00.05 Staphylococcal arthritis and polyarthritis (Pelvic region and thigh)	0.001	0.999	0.000
M00.04 Staphylococcal arthritis and polyarthritis (Hand)	0.001	0.999	0.000
M00.03 Staphylococcal arthritis and polyarthritis (Forearm)	0.001	0.999	0.000
M00.02 Staphylococcal arthritis and polyarthritis (Upper arm)	0.001	0.999	0.000
M00.01 Staphylococcal arthritis and polyarthritis (Shoulder region)	0.001	0.999	0.000
M00.00 Staphylococcal arthritis and polyarthritis (Multiple sites)	0.001	0.999	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations