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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs660240
log Bayes Factor = 127.963
Chromosome 1   position 109,817,838  (GRCh37) Explore rs660240 on Ensembl!
Variant rs660240 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.5 Hyperlipidaemia, unspecified
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.000 1.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.005 0.995
I73 Other peripheral vascular diseases
0.000 0.011 0.989
I73.9 Peripheral vascular disease, unspecified
0.000 0.012 0.988
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.013 0.987
I71 Aortic aneurysm and dissection
0.000 0.014 0.986
Chapter IX Diseases of the circulatory system
0.000 0.014 0.986
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.015 0.985
I21.4 Acute subendocardial myocardial infarction
0.000 0.033 0.967
I74 Arterial embolism and thrombosis
0.000 0.051 0.949
Z95.0 Presence of cardiac pacemaker
0.000 0.071 0.929
I30-I52 Other forms of heart disease
0.000 0.079 0.921
I50 Heart failure
0.000 0.081 0.919
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.087 0.913
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.088 0.912
I35 Nonrheumatic aortic valve disorders
0.000 0.089 0.911
I35.0 Aortic (valve) stenosis
0.000 0.089 0.911
E78.8 Other disorders of lipoprotein metabolism
0.000 0.090 0.910
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.091 0.909
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.108 0.892
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.108 0.892
I50.1 Left ventricular failure
0.000 0.109 0.891
I50.0 Congestive heart failure
0.000 0.117 0.883
I25.3 Aneurysm of heart
0.000 0.131 0.869
I24 Other acute ischaemic heart diseases
0.000 0.144 0.856
I45 Other conduction disorders
0.000 0.153 0.847
I45.1 Other and unspecified right bundle-branch block
0.000 0.165 0.835
I72 Other aneurysm
0.000 0.175 0.825
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.182 0.818
I22 Subsequent myocardial infarction
0.000 0.187 0.813
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.209 0.791
E78.2 Mixed hyperlipidaemia
0.000 0.210 0.790
E78.4 Other hyperlipidaemia
0.000 0.224 0.776
I24.8 Other forms of acute ischaemic heart disease
0.000 0.225 0.775
I50.9 Heart failure, unspecified
0.000 0.228 0.772
I46 Cardiac arrest
0.000 0.243 0.757
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.246 0.754
I25.4 Coronary artery aneurysm
0.000 0.250 0.750
I74.8 Embolism and thrombosis of other arteries
0.000 0.264 0.736
I72.3 Aneurysm of iliac artery
0.000 0.274 0.726
I23 Certain current complications following acute myocardial infarction
0.000 0.278 0.722
I25.5 Ischaemic cardiomyopathy
0.000 0.281 0.719
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
I72.4 Aneurysm of artery of lower extremity
0.000 0.285 0.715
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.287 0.713
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.293 0.707
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.293 0.707
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.293 0.707
I35.8 Other aortic valve disorders
0.000 0.306 0.694
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.307 0.693
I42 Cardiomyopathy
0.000 0.310 0.690
I00-I02 Acute rheumatic fever
0.000 0.310 0.690
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.312 0.688
I40 Acute myocarditis
0.000 0.315 0.685
I70 Atherosclerosis
0.000 0.319 0.681
I73.8 Other specified peripheral vascular diseases
0.000 0.320 0.680
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.320 0.680
I46.0 Cardiac arrest with successful resuscitation
0.000 0.321 0.679
I45.2 Bifascicular block
0.000 0.332 0.668
E78.1 Pure hyperglyceridaemia
0.000 0.333 0.667
I20.8 Other forms of angina pectoris
0.000 0.333 0.667
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.338 0.662
I52 Other heart disorders in diseases classified elsewhere
0.000 0.339 0.661
I48 Atrial fibrillation and flutter
0.000 0.339 0.661
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.339 0.661
I41 Myocarditis in diseases classified elsewhere
0.000 0.339 0.661
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.339 0.661
I32 Pericarditis in diseases classified elsewhere
0.000 0.339 0.661
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.347 0.653
I45.5 Other specified heart block
0.000 0.347 0.652
I35.9 Aortic valve disorder, unspecified
0.000 0.355 0.645
I33 Acute and subacute endocarditis
0.000 0.360 0.640
Z95.2 Presence of prosthetic heart valve
0.000 0.360 0.640
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.360 0.639
I79.1 Aortitis in diseases classified elsewhere
0.000 0.360 0.639
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.360 0.639
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.361 0.639
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.369 0.630
I74.5 Embolism and thrombosis of iliac artery
0.000 0.378 0.622
I72.8 Aneurysm of other specified arteries
0.000 0.378 0.622
I45.0 Right fascicular block
0.000 0.393 0.607
I72.2 Aneurysm of renal artery
0.000 0.400 0.600
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.403 0.597
I10-I15 Hypertensive diseases
0.000 0.403 0.597
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.404 0.596
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.408 0.592
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.408 0.592
I22.8 Subsequent myocardial infarction of other sites
0.000 0.416 0.584
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.417 0.583
I42.2 Other hypertrophic cardiomyopathy
0.000 0.419 0.581
I42.8 Other cardiomyopathies
0.000 0.421 0.579
I71.0 Dissection of aorta [any part]
0.000 0.428 0.572
I20.1 Angina pectoris with documented spasm
0.000 0.429 0.571
I45.3 Trifascicular block
0.000 0.435 0.565
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.440 0.560
I77 Other disorders of arteries and arterioles
0.000 0.441 0.559
I45.9 Conduction disorder, unspecified
0.000 0.442 0.558
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.445 0.555
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.446 0.554
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.456 0.544
I46.1 Sudden cardiac death, so described
0.000 0.457 0.543
I24.1 Dressler's syndrome
0.000 0.461 0.539
I23.8 Other current complications following acute myocardial infarction
0.000 0.478 0.522
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.478 0.522
I37 Pulmonary valve disorders
0.000 0.481 0.518
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.482 0.517
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.482 0.517
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.482 0.517
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.482 0.517
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.482 0.517
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.482 0.517
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.482 0.517
I42.6 Alcoholic cardiomyopathy
0.000 0.484 0.516
I40.0 Infective myocarditis
0.000 0.484 0.515
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.488 0.512
I72.1 Aneurysm of artery of upper extremity
0.000 0.488 0.512
I15 Secondary hypertension
0.000 0.503 0.497
I30 Acute pericarditis
0.000 0.504 0.495
I34 Nonrheumatic mitral valve disorders
0.000 0.505 0.495
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.505 0.495
I42.5 Other restrictive cardiomyopathy
0.000 0.505 0.495
I42.4 Endocardial fibroelastosis
0.000 0.505 0.495
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.505 0.495
I02 Rheumatic chorea
0.000 0.505 0.494
I01 Rheumatic fever with heart involvement
0.000 0.505 0.494
I72.9 Aneurysm of unspecified site
0.000 0.506 0.494
I40.9 Acute myocarditis, unspecified
0.000 0.509 0.491
I40.8 Other acute myocarditis
0.000 0.509 0.491
I40.1 Isolated myocarditis
0.000 0.509 0.491
I70.1 Atherosclerosis of renal artery
0.000 0.510 0.490
I33.0 Acute and subacute infective endocarditis
0.000 0.511 0.489
I70.9 Generalised and unspecified atherosclerosis
0.000 0.512 0.488
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.518 0.482
I45.8 Other specified conduction disorders
0.000 0.519 0.481
I11 Hypertensive heart disease
0.000 0.521 0.479
I00 Rheumatic fever without mention of heart involvement
0.000 0.522 0.477
I36 Nonrheumatic tricuspid valve disorders
0.001 0.525 0.475
I70.8 Atherosclerosis of other arteries
0.000 0.525 0.474
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.526 0.474
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.526 0.474
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.526 0.474
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.526 0.474
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.526 0.474
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.526 0.474
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.526 0.474
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.526 0.474
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.526 0.474
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.526 0.474
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.526 0.474
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.526 0.474
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.526 0.474
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.526 0.474
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.526 0.474
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.526 0.474
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.526 0.474
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.526 0.474
I48.4 Atypical atrial flutter
0.000 0.526 0.474
I48.3 Typical atrial flutter
0.000 0.526 0.474
I48.2 Chronic atrial fibrillation
0.000 0.526 0.474
I48.1 Persistent atrial fibrillation
0.000 0.526 0.474
I48.0 Paroxysmal atrial fibrillation
0.000 0.526 0.474
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.526 0.474
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.526 0.474
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.526 0.474
I78 Diseases of capillaries
0.000 0.540 0.459
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.544 0.456
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.547 0.453
I72.0 Aneurysm of carotid artery
0.000 0.551 0.448
I34.1 Mitral (valve) prolapse
0.000 0.564 0.436
I46.9 Cardiac arrest, unspecified
0.000 0.568 0.432
I38 Endocarditis, valve unspecified
0.000 0.569 0.430
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.571 0.428
I13 Hypertensive heart and renal disease
0.000 0.572 0.428
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.573 0.426
I45.6 Preexcitation syndrome
0.000 0.574 0.425
I70.0 Atherosclerosis of aorta
0.000 0.575 0.425
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.577 0.423
I42.9 Cardiomyopathy, unspecified
0.000 0.578 0.422
I77.2 Rupture of artery
0.000 0.581 0.419
I77.1 Stricture of artery
0.000 0.584 0.416
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.596 0.404
I77.5 Necrosis of artery
0.000 0.599 0.401
I77.4 Coeliac artery compression syndrome
0.000 0.599 0.401
I77.3 Arterial fibromuscular dysplasia
0.000 0.599 0.401
I77.6 Arteritis, unspecified
0.000 0.600 0.400
I33.9 Acute endocarditis, unspecified
0.000 0.601 0.399
I15.9 Seconday hypertension, unspecified
0.000 0.601 0.399
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.603 0.397
I45.4 Nonspecific intraventricular block
0.001 0.605 0.394
I15.1 Hypertension secondary to other renal disorders
0.000 0.606 0.394
O34.2 Maternal care due to uterine scar from previous surgery
0.388 0.612 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.624 0.376
I99 Other and unspecified disorders of circulatory system
0.000 0.627 0.373
I37.9 Pulmonary valve disorder, unspecified
0.000 0.628 0.372
I37.8 Other pulmonary valve disorders
0.000 0.628 0.372
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.628 0.372
I37.0 Pulmonary valve stenosis
0.000 0.628 0.372
I05-I09 Chronic rheumatic heart diseases
0.000 0.636 0.364
I15.8 Other secondary hypertension
0.000 0.644 0.356
I15.2 Hypertension secondary to endocrine disorders
0.000 0.644 0.356
I15.0 Renovascular hypertension
0.000 0.644 0.356
I30.8 Other forms of acute pericarditis
0.000 0.645 0.355
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.645 0.355
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.645 0.355
I01.8 Other acute rheumatic heart disease
0.000 0.645 0.355
I01.2 Acute rheumatic myocarditis
0.000 0.645 0.355
I01.1 Acute rheumatic endocarditis
0.000 0.645 0.355
I01.0 Acute rheumatic pericarditis
0.000 0.645 0.355
I02.9 Rheumatic chorea without heart involvement
0.000 0.645 0.355
I02.0 Rheumatic chorea with heart involvement
0.000 0.645 0.355
I31 Other diseases of pericardium
0.000 0.646 0.354
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.647 0.353
Z95.3 Presence of xenogenic heart valve
0.000 0.648 0.351
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.649 0.351
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.650 0.350
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.650 0.350
I28 Other diseases of pulmonary vessels
0.001 0.652 0.348
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.655 0.345
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.659 0.341
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.001 0.659 0.340
I36.8 Other nonrheumatic tricuspid valve disorders
0.001 0.659 0.340
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.001 0.659 0.340
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.001 0.659 0.340
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.659 0.340
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.660 0.339
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.669 0.331
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.670 0.329
I78.9 Disease of capillaries, unspecified
0.000 0.670 0.329
I77.0 Arteriovenous fistula, acquired
0.000 0.671 0.329
I77.8 Other specified disorders of arteries and arterioles
0.000 0.673 0.327
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.673 0.326
I10 Essential (primary) hypertension
0.000 0.674 0.326
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.676 0.324
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.681 0.319
I30.1 Infective pericarditis
0.000 0.687 0.313
I78.8 Other diseases of capillaries
0.000 0.688 0.312
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.688 0.312
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.693 0.307
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.693 0.307
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.693 0.307
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.693 0.307
I95 Hypotension
0.000 0.693 0.307
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.695 0.305
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.697 0.303
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.697 0.303
Z82.2 Family history of deafness and hearing loss
0.000 0.697 0.303
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.702 0.298
I28.8 Other specified diseases of pulmonary vessels
0.000 0.708 0.292
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.717 0.283
I51 Complications and ill-defined descriptions of heart disease
0.000 0.717 0.283
Z82.1 Family history of blindness and visual loss
0.000 0.720 0.280
I95.1 Orthostatic hypotension
0.000 0.725 0.275
I09 Other rheumatic heart diseases
0.000 0.734 0.266
I06 Rheumatic aortic valve diseases
0.000 0.739 0.261
I30.9 Acute pericarditis, unspecified
0.000 0.739 0.260
I31.8 Other specified diseases of pericardium
0.000 0.746 0.254
I31.2 Haemopericardium, not elsewhere classified
0.000 0.746 0.254
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.750 0.249
I28.1 Aneurysm of pulmonary artery
0.001 0.750 0.249
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.750 0.249
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.758 0.242
I07 Rheumatic tricuspid valve diseases
0.000 0.761 0.239
O34 Maternal care for known or suspected abnormality of pelvic organs
0.239 0.761 0.000
I97.1 Other functional disturbances following cardiac surgery
0.000 0.761 0.239
I31.0 Chronic adhesive pericarditis
0.000 0.766 0.234
I95.9 Hypotension, unspecified
0.000 0.769 0.231
I37.1 Pulmonary valve insufficiency
0.001 0.770 0.229
I42.0 Dilated cardiomyopathy
0.000 0.776 0.223
S00.8 Superficial injury of other parts of head
0.000 0.780 0.220
I31.1 Chronic constrictive pericarditis
0.000 0.782 0.218
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.782 0.217
I97.0 Postcardiotomy syndrome
0.000 0.782 0.217
I51.0 Cardiac septal defect, acquired
0.000 0.783 0.217
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.787 0.212
I31.9 Disease of pericardium, unspecified
0.000 0.789 0.211
I51.6 Cardiovascular disease, unspecified
0.000 0.794 0.206
I34.0 Mitral (valve) insufficiency
0.000 0.795 0.205
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.797 0.203
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.797 0.203
O34.8 Maternal care for other abnormalities of pelvic organs
0.200 0.800 0.000
I51.8 Other ill-defined heart diseases
0.000 0.801 0.199
I05 Rheumatic mitral valve diseases
0.000 0.801 0.199
O34.0 Maternal care for congenital malformation of uterus
0.198 0.802 0.000
I51.9 Heart disease, unspecified
0.000 0.804 0.196
I09.9 Rheumatic heart disease, unspecified
0.000 0.804 0.196
I51.7 Cardiomegaly
0.000 0.807 0.193
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.807 0.193
I49 Other cardiac arrhythmias
0.000 0.809 0.191
I09.8 Other specified rheumatic heart diseases
0.000 0.809 0.191
I09.2 Chronic rheumatic pericarditis
0.000 0.809 0.191
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.809 0.191
I09.0 Rheumatic myocarditis
0.000 0.809 0.191
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.812 0.187
I06.8 Other rheumatic aortic valve diseases
0.000 0.812 0.187
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.812 0.187
I06.1 Rheumatic aortic insufficiency
0.000 0.812 0.187
I06.0 Rheumatic aortic stenosis
0.000 0.812 0.187
I31.3 Pericardial effusion (noninflammatory)
0.000 0.819 0.181
I95.2 Hypotension due to drugs
0.000 0.820 0.180
I12 Hypertensive renal disease
0.000 0.822 0.178
O34.1 Maternal care for tumour of corpus uteri
0.177 0.823 0.000
O34.3 Maternal care for cervical incompetence
0.173 0.827 0.000
I07.9 Tricuspid valve disease, unspecified
0.000 0.828 0.172
I07.8 Other tricuspid valve diseases
0.000 0.828 0.172
I07.2 Tricuspid stenosis with insufficiency
0.000 0.828 0.172
I07.0 Tricuspid stenosis
0.000 0.828 0.172
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.172 0.828 0.000
O34.6 Maternal care for abnormality of vagina
0.172 0.828 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.172 0.828 0.000
Z82.3 Family history of stroke
0.000 0.833 0.166
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.835 0.165
S00 Superficial injury of head
0.000 0.836 0.164
I51.5 Myocardial degeneration
0.000 0.836 0.164
I49.1 Atrial premature depolarisation
0.000 0.838 0.162
I26 Pulmonary embolism
0.004 0.839 0.158
I05.2 Mitral stenosis with insufficiency
0.000 0.840 0.160
I95.0 Idiopathic hypotension
0.000 0.840 0.160
O34.4 Maternal care for other abnormalities of cervix
0.160 0.840 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.158 0.842 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.842 0.158
I73.0 Raynaud's syndrome
0.000 0.843 0.157
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.001 0.844 0.154
I95.8 Other hypotension
0.000 0.845 0.155
I49.5 Sick sinus syndrome
0.000 0.846 0.154
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.847 0.152
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.847 0.152
I98.0 Cardiovascular syphilis
0.000 0.847 0.152
I07.1 Tricuspid insufficiency
0.000 0.851 0.149
I27 Other pulmonary heart diseases
0.000 0.852 0.147
I49.8 Other specified cardiac arrhythmias
0.000 0.853 0.147
I78.1 Naevus, nonneoplastic
0.000 0.854 0.146
S00.0 Superficial injury of scalp
0.000 0.854 0.146
S00.7 Multiple superficial injuries of head
0.000 0.855 0.145
I05.8 Other mitral valve diseases
0.000 0.857 0.143
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.860 0.140
I49.2 Junctional premature depolarisation
0.000 0.863 0.137
I05.1 Rheumatic mitral insufficiency
0.000 0.864 0.135
I05.0 Mitral stenosis
0.000 0.869 0.130
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.875 0.125
I08 Multiple valve diseases
0.000 0.876 0.124
S00.1 Contusion of eyelid and periocular area
0.000 0.876 0.124
S00.3 Superficial injury of nose
0.000 0.882 0.118
I49.4 Other and unspecified premature depolarisation
0.000 0.885 0.115
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.885 0.115
I27.9 Pulmonary heart disease, unspecified
0.000 0.885 0.114
S00.5 Superficial injury of lip and oral cavity
0.000 0.886 0.114
I47 Paroxysmal tachycardia
0.000 0.888 0.112
Z95.4 Presence of other heart-valve replacement
0.000 0.888 0.111
I35.1 Aortic (valve) insufficiency
0.001 0.890 0.110
I27.1 Kyphoscoliotic heart disease
0.000 0.894 0.106
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.003 0.894 0.103
I27.8 Other specified pulmonary heart diseases
0.000 0.898 0.102
S00.4 Superficial injury of ear
0.000 0.901 0.099
I51.4 Myocarditis, unspecified
0.001 0.902 0.097
I12.9 Hypertensive renal disease without renal failure
0.000 0.914 0.086
I08.9 Multiple valve disease, unspecified
0.000 0.916 0.084
S00.9 Superficial injury of head, part unspecified
0.000 0.918 0.082
I08.8 Other multiple valve diseases
0.000 0.926 0.074
I05.9 Mitral valve disease, unspecified
0.000 0.926 0.073
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.927 0.073
I47.0 Reentry ventricular arrhythmia
0.000 0.932 0.068
I49.0 Ventricular fibrillation and flutter
0.000 0.939 0.061
I27.0 Primary pulmonary hypertension
0.000 0.946 0.054
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.946 0.053
I47.2 Ventricular tachycardia
0.000 0.947 0.053
S00-S09 Injuries to the head
0.000 0.953 0.047
I27.2 Other secondary pulmonary hypertension
0.000 0.955 0.045
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.957 0.043
I08.0 Disorders of both mitral and aortic valves
0.000 0.960 0.040
S02 Fracture of skull and facial bones
0.000 0.961 0.039
S01 Open wound of head
0.000 0.962 0.038
S02.0 Fracture of vault of skull
0.000 0.963 0.037
S01.9 Open wound of head, part unspecified
0.000 0.963 0.037
S02.2 Fracture of nasal bones
0.000 0.963 0.036
S02.00 Fracture of vault of skull (closed)
0.000 0.964 0.036
S02.20 Fracture of nasal bones (closed)
0.000 0.965 0.035
S08 Traumatic amputation of part of head
0.000 0.966 0.034
S07 Crushing injury of head
0.000 0.966 0.034
S04 Injury of cranial nerves
0.000 0.966 0.034
S01.7 Multiple open wounds of head
0.000 0.966 0.034
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.968 0.032
S05 Injury of eye and orbit
0.000 0.968 0.032
S01.3 Open wound of ear
0.000 0.968 0.032
I49.9 Cardiac arrhythmia, unspecified
0.000 0.968 0.032
S09 Other and unspecified injuries of head
0.000 0.968 0.032
S01.1 Open wound of eyelid and periocular area
0.000 0.969 0.031
K05.3 Chronic periodontitis
0.030 0.970 0.000
S02.8 Fractures of other skull and facial bones
0.000 0.972 0.028
S02.7 Multiple fractures involving skull and facial bones
0.000 0.972 0.028
S01.2 Open wound of nose
0.000 0.973 0.027
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.973 0.027
S02.01 Fracture of vault of skull (open)
0.000 0.973 0.027
S09.8 Other specified injuries of head
0.000 0.973 0.027
S02.6 Fracture of mandible
0.000 0.973 0.026
S02.21 Fracture of nasal bones (open)
0.000 0.974 0.026
S05.8 Other injuries of eye and orbit
0.000 0.974 0.025
S03.2 Dislocation of tooth
0.000 0.975 0.025
S02.3 Fracture of orbital floor
0.000 0.975 0.025
S04.9 Injury of unspecified cranial nerve
0.000 0.975 0.025
S04.8 Injury of other cranial nerves
0.000 0.975 0.025
S04.7 Injury of accessory nerve
0.000 0.975 0.025
S04.6 Injury of acoustic nerve
0.000 0.975 0.025
S04.5 Injury of facial nerve
0.000 0.975 0.025
S04.4 Injury of abducent nerve
0.000 0.975 0.025
S04.3 Injury of trigeminal nerve
0.000 0.975 0.025
S04.2 Injury of trochlear nerve
0.000 0.975 0.025
S04.1 Injury of oculomotor nerve
0.000 0.975 0.025
S04.0 Injury of optic nerve and pathways
0.000 0.975 0.025
S07.9 Crushing injury of head, part unspecified
0.000 0.975 0.025
S07.8 Crushing injury of other parts of head
0.000 0.975 0.025
S07.1 Crushing injury of skull
0.000 0.975 0.025
S07.0 Crushing injury of face
0.000 0.975 0.025
S08.9 Traumatic amputation of unspecified part of head
0.000 0.975 0.025
S08.8 Traumatic amputation of other parts of head
0.000 0.975 0.025
S08.1 Traumatic amputation of ear
0.000 0.975 0.025
S08.0 Avulsion of scalp
0.000 0.975 0.025
S05.1 Contusion of eyeball and orbital tissues
0.000 0.976 0.024
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head
0.000 0.976 0.023
S03.4 Sprain and strain of jaw
0.000 0.976 0.023
S03.3 Dislocation of other and unspecified parts of head
0.000 0.976 0.023
S03.0 Dislocation of jaw
0.000 0.976 0.023
S05.7 Avulsion of eye
0.000 0.977 0.023
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.977 0.023
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.977 0.023
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.977 0.023
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.977 0.023
S02.4 Fracture of malar and maxillary bones
0.000 0.977 0.023
I60-I69 Cerebrovascular diseases
0.000 0.977 0.023
S09.7 Multiple injuries of head
0.000 0.977 0.023
S09.2 Traumatic rupture of ear drum
0.000 0.977 0.023
S09.1 Injury of muscle and tendon of head
0.000 0.977 0.023
S01.4 Open wound of cheek and temporomandibular area
0.000 0.977 0.023
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.977 0.023
I49.3 Ventricular premature depolarisation
0.001 0.977 0.022
S05.9 Injury of eye and orbit, part unspecified
0.000 0.977 0.022
S02.5 Fracture of tooth
0.000 0.978 0.022
S02.1 Fracture of base of skull
0.000 0.978 0.022
I44 Atrioventricular and left bundle-branch block
0.000 0.979 0.021
S09.0 Injury of blood vessels of head, not elsewhere classified
0.000 0.979 0.021
S02.81 Fractures of other skull and facial bones (open)
0.000 0.979 0.020
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.979 0.020
I69 Sequelae of cerebrovascular disease
0.000 0.980 0.020
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.980 0.020
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.980 0.020
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.980 0.020
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.980 0.020
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.980 0.020
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.980 0.020
S03.1 Dislocation of septal cartilage of nose
0.000 0.981 0.019
S02.61 Fracture of mandible (open)
0.000 0.981 0.019
K05 Gingivitis and periodontal diseases
0.019 0.981 0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.981 0.018
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.981 0.019
S02.31 Fracture of orbital floor (open)
0.000 0.982 0.018
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.982 0.017
I65.2 Occlusion and stenosis of carotid artery
0.000 0.982 0.018
S02.60 Fracture of mandible (closed)
0.000 0.983 0.017
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.983 0.017
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.983 0.017
S09.9 Unspecified injury of head
0.000 0.984 0.016
I44.4 Left anterior fascicular block
0.000 0.984 0.016
K05.6 Periodontal disease, unspecified
0.016 0.984 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.984 0.016
S02.51 Fracture of tooth (open)
0.000 0.984 0.016
S01.5 Open wound of lip and oral cavity
0.000 0.984 0.016
I44.5 Left posterior fascicular block
0.000 0.985 0.015
K05.1 Chronic gingivitis
0.015 0.985 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.985 0.015
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.985 0.015
S02.30 Fracture of orbital floor (closed)
0.000 0.985 0.014
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.986 0.014
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.986 0.014
K05.2 Acute periodontitis
0.014 0.986 0.000
K05.4 Periodontosis
0.014 0.986 0.000
K05.0 Acute gingivitis
0.014 0.986 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.987 0.013
S02.11 Fracture of base of skull (open)
0.000 0.987 0.013
S02.10 Fracture of base of skull (closed)
0.000 0.987 0.013
I65.1 Occlusion and stenosis of basilar artery
0.000 0.987 0.013
I68.0 Cerebral amyloid angiopathy
0.000 0.987 0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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