TreeWAS – Variant ID: rs6687758

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C18 Malignant neoplasm of colon	0.919	0.081	0.000
C18.4 Transverse colon	0.909	0.091	0.000
C18.2 Ascending colon	0.900	0.100	0.000
C18.9 Colon, unspecified	0.888	0.112	0.000
C18.7 Sigmoid colon	0.876	0.124	0.000
C18.0 Caecum	0.868	0.132	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.789	0.211	0.000
C18.5 Splenic flexure	0.783	0.217	0.000
C18.8 Overlapping lesion of colon	0.694	0.306	0.000
C18.1 Appendix	0.611	0.389	0.000
C18.3 Hepatic flexure	0.543	0.456	0.000
C18.6 Descending colon	0.537	0.463	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.178	0.822	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.153	0.847	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.133	0.867	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.105	0.895	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.088	0.912	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.072	0.928	0.000
C15-C26 Malignant neoplasms of digestive organs	0.058	0.942	0.000
C15 Malignant neoplasm of oesophagus	0.053	0.947	0.000
C15.5 Lower third of oesophagus	0.052	0.948	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.049	0.951	0.000
C17 Malignant neoplasm of small intestine	0.045	0.955	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.044	0.956	0.000
C22.9 Liver, unspecified	0.044	0.956	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.039	0.961	0.000
C15.3 Upper third of oesophagus	0.039	0.961	0.000
C15.8 Overlapping lesion of oesophagus	0.038	0.962	0.000
C15.2 Abdominal part of oesophagus	0.038	0.962	0.000
C15.1 Thoracic part of oesophagus	0.038	0.962	0.000
C15.0 Cervical part of oesophagus	0.038	0.962	0.000
C22.0 Liver cell carcinoma	0.038	0.962	0.000
Y84.8 Other medical procedures	0.000	0.962	0.038
C26.0 Intestinal tract, part unspecified	0.037	0.963	0.000
C17.1 Jejunum	0.036	0.964	0.000
C17.9 Small intestine, unspecified	0.036	0.964	0.000
C22.7 Other specified carcinomas of liver	0.035	0.965	0.000
C22.4 Other sarcomas of liver	0.035	0.965	0.000
C22.3 Angiosarcoma of liver	0.035	0.965	0.000
C22.2 Hepatoblastoma	0.035	0.965	0.000
C20 Malignant neoplasm of rectum	0.035	0.965	0.000
C15.9 Oesophagus, unspecified	0.035	0.965	0.000
C17.8 Overlapping lesion of small intestine	0.032	0.968	0.000
C17.3 Meckel's diverticulum	0.032	0.968	0.000
C26.8 Overlapping lesion of digestive system	0.032	0.968	0.000
C26.1 Spleen	0.032	0.968	0.000
C17.2 Ileum	0.032	0.968	0.000
C21 Malignant neoplasm of anus and anal canal	0.031	0.969	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.030	0.970	0.000
C24.1 Ampulla of Vater	0.029	0.971	0.000
C24.8 Overlapping lesion of biliary tract	0.028	0.972	0.000
C24.9 Biliary tract, unspecified	0.027	0.973	0.000
C26.9 Ill-defined sites within the digestive system	0.027	0.973	0.000
C17.0 Duodenum	0.027	0.973	0.000
C22.1 Intrahepatic bile duct carcinoma	0.026	0.973	0.000
C24.0 Extrahepatic bile duct	0.026	0.974	0.000
C23 Malignant neoplasm of gallbladder	0.024	0.975	0.000
C15.4 Middle third of oesophagus	0.024	0.976	0.000
C21.2 Cloacogenic zone	0.023	0.977	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.979	0.021
F31 Bipolar affective disorder	0.000	0.979	0.021
C21.0 Anus, unspecified	0.021	0.979	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.021	0.979	0.000
K62.1 Rectal polyp	0.020	0.980	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.980	0.020
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.980	0.020
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.980	0.020
D69.3 Idiopathic thrombocytopenic purpura	0.018	0.982	0.000
C21.1 Anal canal	0.017	0.983	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.983	0.017
C16 Malignant neoplasm of stomach	0.016	0.983	0.000
F31.8 Other bipolar affective disorders	0.000	0.984	0.015
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.985	0.015
F31.7 Bipolar affective disorder, currently in remission	0.000	0.985	0.015
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.985	0.015
S90.8 Other superficial injuries of ankle and foot	0.014	0.985	0.000
S90 Superficial injury of ankle and foot	0.014	0.986	0.000
D69 Purpura and other haemorrhagic conditions	0.014	0.986	0.000
C25 Malignant neoplasm of pancreas	0.014	0.986	0.000
S90-S99 Injuries to the ankle and foot	0.014	0.986	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.986	0.013
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.987	0.013
C16.0 Cardia	0.013	0.987	0.000
Y84.0 Cardiac catheterisation	0.000	0.987	0.013
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.013	0.987	0.000
S91 Open wound of ankle and foot	0.013	0.987	0.000
S92.30 Fracture of metatarsal bone (closed)	0.012	0.987	0.000
S92 Fracture of foot, except ankle	0.012	0.987	0.000
Y84.6 Urinary catheterisation	0.000	0.988	0.012
S92.3 Fracture of metatarsal bone	0.012	0.988	0.000
C16.8 Overlapping lesion of stomach	0.012	0.988	0.000
C16.4 Pylorus	0.012	0.988	0.000
C16.1 Fundus of stomach	0.012	0.988	0.000
D69.5 Secondary thrombocytopenia	0.012	0.988	0.000
Y84.9 Medical procedure, unspecified	0.000	0.988	0.012
S93.0 Dislocation of ankle joint	0.012	0.988	0.000
D69.9 Haemorrhagic condition, unspecified	0.012	0.988	0.000
D69.0 Allergic purpura	0.012	0.988	0.000
D69.4 Other primary thrombocytopenia	0.012	0.988	0.000
S90.0 Contusion of ankle	0.011	0.989	0.000
Y84.4 Aspiration of fluid	0.000	0.989	0.011
C16.6 Greater curvature of stomach, unspecified	0.011	0.989	0.000
S91.0 Open wound of ankle	0.011	0.989	0.000
Y84.7 Blood-sampling	0.000	0.989	0.011
Y84.5 Insertion of gastric or duodenal sound	0.000	0.989	0.011
Y84.3 Shock therapy	0.000	0.989	0.011
S96 Injury of muscle and tendon at ankle and foot level	0.011	0.989	0.000
C16.3 Pyloric antrum	0.011	0.989	0.000
C25.3 Pancreatic duct	0.011	0.989	0.000
S90.1 Contusion of toe(s) without damage to nail	0.011	0.989	0.000
S93.1 Dislocation of toe(s)	0.011	0.989	0.000
H40.0 Glaucoma suspect	0.011	0.989	0.000
S92.2 Fracture of other tarsal bone(s)	0.011	0.989	0.000
C16.5 Lesser curvature of stomach, unspecified	0.010	0.990	0.000
C16.2 Body of stomach	0.010	0.990	0.000
C25.7 Other parts of pancreas	0.010	0.990	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.010	0.990	0.000
S90.2 Contusion of toe(s) with damage to nail	0.010	0.990	0.000
D69.8 Other specified haemorrhagic conditions	0.010	0.990	0.000
D69.1 Qualitative platelet defects	0.010	0.990	0.000
C25.8 Overlapping lesion of pancreas	0.010	0.990	0.000
C25.4 Endocrine pancreas	0.010	0.990	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.010	0.990	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.990	0.010
S98 Traumatic amputation of ankle and foot	0.010	0.990	0.000
S97 Crushing injury of ankle and foot	0.010	0.990	0.000
S95 Injury of blood vessels at ankle and foot level	0.010	0.990	0.000
S94 Injury of nerves at ankle and foot level	0.010	0.990	0.000
D69.2 Other nonthrombocytopenic purpura	0.010	0.990	0.000
S91.2 Open wound of toe(s) with damage to nail	0.010	0.990	0.000
S91.3 Open wound of other parts of foot	0.010	0.990	0.000
S91.1 Open wound of toe(s) without damage to nail	0.010	0.990	0.000
M47.89 Other spondylosis (Site unspecified)	0.000	0.990	0.010
S92.20 Fracture of other tarsal bone(s) (closed)	0.010	0.990	0.000
K63.5 Polyp of colon	0.010	0.990	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.009	0.990	0.000
S93.4 Sprain and strain of ankle	0.009	0.990	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.009	0.990	0.000
S93.5 Sprain and strain of toe(s)	0.009	0.990	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.009	0.990	0.000
S90.3 Contusion of other and unspecified parts of foot	0.009	0.991	0.000
S91.7 Multiple open wounds of ankle and foot	0.009	0.991	0.000
S92.9 Fracture of foot, unspecified	0.009	0.991	0.000
S92.5 Fracture of other toe	0.009	0.991	0.000
H40 Glaucoma	0.009	0.991	0.000
S92.31 Fracture of metatarsal bone (open)	0.009	0.991	0.000
S92.7 Multiple fractures of foot	0.009	0.991	0.000
S92.1 Fracture of talus	0.009	0.991	0.000
H35.4 Peripheral retinal degeneration	0.000	0.992	0.008
C25.2 Tail of pancreas	0.008	0.992	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.008	0.992	0.000
Y84.1 Kidney dialysis	0.000	0.992	0.008
H35 Other retinal disorders	0.000	0.992	0.008
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.008	0.992	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.008	0.992	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.008	0.992	0.000
S99 Other and unspecified injuries of ankle and foot	0.008	0.992	0.000
H40.9 Glaucoma, unspecified	0.008	0.992	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.992	0.008
H40.1 Primary open-angle glaucoma	0.008	0.992	0.000
H50.1 Divergent concomitant strabismus	0.008	0.992	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.008	0.992	0.000
S92.0 Fracture of calcaneus	0.008	0.992	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.008	0.992	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.992	0.008
H35.7 Separation of retinal layers	0.000	0.992	0.008
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.007	0.992	0.000
M47.8 Other spondylosis	0.000	0.992	0.008
H40.5 Glaucoma secondary to other eye disorders	0.008	0.992	0.000
H40.3 Glaucoma secondary to eye trauma	0.008	0.992	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.992	0.008
H35.3 Degeneration of macula and posterior pole	0.000	0.992	0.008
S94.9 Injury of unspecified nerve at ankle and foot level	0.007	0.992	0.000
S94.8 Injury of other nerves at ankle and foot level	0.007	0.992	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.007	0.992	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.007	0.992	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.007	0.992	0.000
S94.1 Injury of medial plantar nerve	0.007	0.992	0.000
S94.0 Injury of lateral plantar nerve	0.007	0.992	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.007	0.992	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.007	0.992	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.007	0.992	0.000
S95.2 Injury of dorsal vein of foot	0.007	0.992	0.000
S95.1 Injury of plantar artery of foot	0.007	0.992	0.000
S95.0 Injury of dorsal artery of foot	0.007	0.992	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.007	0.992	0.000
S97.1 Crushing injury of toe(s)	0.007	0.992	0.000
S97.0 Crushing injury of ankle	0.007	0.992	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.007	0.992	0.000
S98.3 Traumatic amputation of other parts of foot	0.007	0.992	0.000
S98.2 Traumatic amputation of two or more toes	0.007	0.992	0.000
S98.1 Traumatic amputation of one toe	0.007	0.992	0.000
S98.0 Traumatic amputation of foot at ankle level	0.007	0.992	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.993	0.007
C25.1 Body of pancreas	0.007	0.993	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.993	0.007
S92.4 Fracture of great toe	0.007	0.993	0.000
F30-F39 Mood [affective] disorders	0.000	0.993	0.007
F32 Depressive episode	0.000	0.993	0.007
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.993	0.007
S93.40 Sprain of unspecified ligament of ankle	0.007	0.993	0.000
H40.8 Other glaucoma	0.007	0.993	0.000
H31 Other disorders of choroid	0.000	0.993	0.007
H30-H36 Disorders of choroid and retina	0.000	0.993	0.007
S92.50 Fracture of other toe (closed)	0.007	0.993	0.000
Z89.4 Acquired absence of foot and ankle	0.007	0.993	0.000
S92.91 Fracture of foot, unspecified (open)	0.007	0.993	0.000
S92.90 Fracture of foot, unspecified (closed)	0.007	0.993	0.000
H40.6 Glaucoma secondary to drugs	0.007	0.993	0.000
S92.71 Multiple fractures of foot (open)	0.007	0.993	0.000
C25.9 Pancreas, unspecified	0.007	0.993	0.000
H31.8 Other specified disorders of choroid	0.000	0.993	0.007
S92.11 Fracture of talus (open)	0.007	0.993	0.000
H34 Retinal vascular occlusions	0.000	0.993	0.007
S92.51 Fracture of other toe (open)	0.007	0.993	0.000
S92.70 Multiple fractures of foot (closed)	0.006	0.993	0.000
H35.9 Retinal disorder, unspecified	0.000	0.993	0.007
S92.10 Fracture of talus (closed)	0.006	0.993	0.000
M47.82 Other spondylosis (Cervical region)	0.000	0.994	0.006
H34.2 Other retinal artery occlusions	0.000	0.994	0.006
H35.1 Retinopathy of prematurity	0.000	0.994	0.006
M47.84 Other spondylosis (Thoracic region)	0.000	0.994	0.006
T43.6 Psychostimulants with abuse potential	0.000	0.994	0.006
H34.8 Other retinal vascular occlusions	0.000	0.994	0.006
H35.8 Other specified retinal disorders	0.000	0.994	0.006
S99.8 Other specified injuries of ankle and foot	0.006	0.994	0.000
S99.7 Multiple injuries of ankle and foot	0.006	0.994	0.000
H31.0 Chorioretinal scars	0.000	0.994	0.006
H40.4 Glaucoma secondary to eye inflammation	0.006	0.994	0.000
S92.01 Fracture of calcaneus (open)	0.006	0.994	0.000
H33 Retinal detachments and breaks	0.000	0.994	0.006
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.994	0.006
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.994	0.006
H33.0 Retinal detachment with retinal break	0.000	0.994	0.006
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.994	0.006
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.994	0.006
H35.2 Other proliferative retinopathy	0.000	0.994	0.006
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.994	0.006
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.994	0.006
H40.2 Primary angle-closure glaucoma	0.006	0.994	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.994	0.005
T43.9 Psychotropic drug, unspecified	0.000	0.994	0.005
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.994	0.005
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.994	0.005
F38 Other mood [affective] disorders	0.000	0.995	0.005
F30 Manic episode	0.000	0.995	0.005
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.995	0.005
H30 Chorioretinal inflammation	0.000	0.995	0.005
H31.9 Disorder of choroid, unspecified	0.000	0.995	0.005
H31.4 Choroidal detachment	0.000	0.995	0.005
H31.3 Choroidal haemorrhage and rupture	0.000	0.995	0.005
H31.2 Hereditary choroidal dystrophy	0.000	0.995	0.005
H31.1 Choroidal degeneration	0.000	0.995	0.005
H33.3 Retinal breaks without detachment	0.000	0.995	0.005
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.995	0.005
D69.6 Thrombocytopenia, unspecified	0.005	0.995	0.000
T43.2 Other and unspecified antidepressants	0.000	0.995	0.005
Y84.2 Radiological procedure and radiotherapy	0.000	0.995	0.005
F32.0 Mild depressive episode	0.000	0.995	0.005
H34.9 Retinal vascular occlusion, unspecified	0.000	0.995	0.005
F39 Unspecified mood [affective] disorder	0.000	0.995	0.005
H34.0 Transient retinal artery occlusion	0.000	0.995	0.005
F32.8 Other depressive episodes	0.000	0.995	0.005
H35.6 Retinal haemorrhage	0.000	0.995	0.005
F32.1 Moderate depressive episode	0.000	0.995	0.005
O20.0 Threatened abortion	0.000	0.995	0.005
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.995	0.005
H33.4 Traction detachment of retina	0.000	0.995	0.005
S92.40 Fracture of great toe (closed)	0.004	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.995	0.005
F34 Persistent mood [affective] disorders	0.000	0.995	0.004
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.995	0.005
S92.41 Fracture of great toe (open)	0.004	0.995	0.000
S92.00 Fracture of calcaneus (closed)	0.004	0.995	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.995	0.005
F30.2 Mania with psychotic symptoms	0.000	0.995	0.004
F30.9 Manic episode, unspecified	0.000	0.996	0.004
C16.9 Stomach, unspecified	0.004	0.996	0.001
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.996	0.004
T42.4 Benzodiazepines	0.000	0.996	0.004
T45.0 Antiallergic and antiemetic drugs	0.000	0.996	0.004
Z89 Acquired absence of limb	0.004	0.996	0.000
F30.8 Other manic episodes	0.000	0.996	0.004
F30.1 Mania without psychotic symptoms	0.000	0.996	0.004
F38.8 Other specified mood [affective] disorders	0.000	0.996	0.004
F38.1 Other recurrent mood [affective] disorders	0.000	0.996	0.004
F38.0 Other single mood [affective] disorders	0.000	0.996	0.004
C25.0 Head of pancreas	0.004	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.996	0.004
Z89.9 Acquired absence of limb, unspecified	0.004	0.996	0.000
H30.9 Chorioretinal inflammation, unspecified	0.000	0.996	0.004
H30.8 Other chorioretinal inflammations	0.000	0.996	0.004
H30.2 Posterior cyclitis	0.000	0.996	0.004
H30.1 Disseminated chorioretinal inflammation	0.000	0.996	0.004
H30.0 Focal chorioretinal inflammation	0.000	0.996	0.004
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.000	0.996	0.004
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
H34.1 Central retinal artery occlusion	0.000	0.996	0.004
V18.0 Driver injured in nontraffic accident	0.004	0.996	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.004	0.996	0.000
S99.9 Unspecified injury of ankle and foot	0.004	0.996	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.996	0.004
N81.3 Complete uterovaginal prolapse	0.000	0.996	0.004
T78.2 Anaphylactic shock, unspecified	0.004	0.996	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.996	0.004
O20 Haemorrhage in early pregnancy	0.000	0.996	0.004
H40-H42 Glaucoma	0.004	0.996	0.000
H35.5 Hereditary retinal dystrophy	0.000	0.996	0.004
M20.2 Hallux rigidus	0.000	0.996	0.004
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.996	0.004
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.996	0.004
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.996	0.004
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.996	0.003
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.996	0.003
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.996	0.003
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.996	0.003
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.996	0.003
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.996	0.003
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.996	0.003
T44.0 Anticholinesterase agents	0.000	0.996	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.996	0.004
H33.5 Other retinal detachments	0.000	0.996	0.004
T42.0 Hydantoin derivatives	0.000	0.996	0.004
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.996	0.003
F34.8 Other persistent mood [affective] disorders	0.000	0.996	0.003
F34.0 Cyclothymia	0.000	0.996	0.003
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.996	0.003
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.996	0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.996	0.003
K72.9 Hepatic failure, unspecified	0.004	0.996	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.997	0.003
T36 Poisoning by systemic antibiotics	0.000	0.997	0.003
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.997	0.003
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.997	0.003
Z89.2 Acquired absence of upper limb above wrist	0.003	0.997	0.000
T42.1 Iminostilbenes	0.000	0.997	0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.997	0.003
T42.3 Barbiturates	0.000	0.997	0.003
T42.2 Succinimides and oxazolidinediones	0.000	0.997	0.003
Z89.8 Acquired absence of upper and lower limbs [any level]	0.003	0.997	0.000
L28.0 Lichen simplex chronicus	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.997	0.003
F30.0 Hypomania	0.000	0.997	0.003
O20.8 Other haemorrhage in early pregnancy	0.000	0.997	0.003
Z89.3 Acquired absence of both upper limbs [any level]	0.003	0.997	0.000
Z89.1 Acquired absence of hand and wrist	0.003	0.997	0.000
H36 Retinal disorders in diseases classified elsewhere	0.000	0.997	0.003
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.997	0.003
T45.5 Anticoagulants	0.000	0.997	0.003
Z34 Supervision of normal pregnancy	0.000	0.997	0.003
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.997	0.003
T45.8 Other primarily systemic and haematological agents	0.000	0.997	0.003
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.003
T45.6 Fibrinolysis-affecting drugs	0.000	0.997	0.003
T45.4 Iron and its compounds	0.000	0.997	0.003
T45.3 Enzymes, not elsewhere classified	0.000	0.997	0.003
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.997	0.003
G91.9 Hydrocephalus, unspecified	0.000	0.997	0.003
M10.9 Gout, unspecified	0.000	0.997	0.003
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.997	0.003
H42 Glaucoma in diseases classified elsewhere	0.003	0.997	0.000
H50 Other strabismus	0.003	0.997	0.000
Z89.5 Acquired absence of leg at or below knee	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.997	0.003
G91.2 Normal-pressure hydrocephalus	0.000	0.997	0.003
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.997	0.003
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.997	0.003
T46.7 Peripheral vasodilators	0.000	0.997	0.003
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.997	0.003
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.997	0.003
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.997	0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.997	0.003
S70.9 Superficial injury of hip and thigh, unspecified	0.003	0.997	0.000
H50.2 Vertical strabismus	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.997	0.003
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.997	0.003
T38.7 Androgens and anabolic congeners	0.000	0.997	0.003
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.003
T38.5 Other oestrogens and progestogens	0.000	0.997	0.003
T38.4 Oral contraceptives	0.000	0.997	0.003
T38.2 Antithyroid drugs	0.000	0.997	0.003
T38.0 Glucocorticoids and synthetic analogues	0.000	0.997	0.003
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.003	0.997	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.003	0.997	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.997	0.003
T46.1 Calcium-channel blockers	0.000	0.997	0.003
G91 Hydrocephalus	0.000	0.997	0.003
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.003
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.997	0.003
T37.5 Antiviral drugs	0.000	0.997	0.003
T37.4 Anthelminthics	0.000	0.997	0.003
T37.3 Other antiprotozoal drugs	0.000	0.997	0.003
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.997	0.003
T37.1 Antimycobacterial drugs	0.000	0.997	0.003
T37.0 Sulphonamides	0.000	0.997	0.003
T41.5 Therapeutic gases	0.000	0.997	0.003
T41.4 Anaesthetic, unspecified	0.000	0.997	0.003
T41.3 Local anaesthetics	0.000	0.997	0.003
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
T41.1 Intravenous anaesthetics	0.000	0.997	0.003
T41.0 Inhaled anaesthetics	0.000	0.997	0.003
T49.9 Topical agent, unspecified	0.000	0.997	0.003
T49.8 Other topical agents	0.000	0.997	0.003
T49.7 Dental drugs, topically applied	0.000	0.997	0.003
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.003
T49.5 Ophthalmological drugs and preparations	0.000	0.997	0.003
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.003
T49.3 Emollients, demulcents and protectants	0.000	0.997	0.003
T49.2 Local astringents and local detergents	0.000	0.997	0.003
T49.1 Antipruritics	0.000	0.997	0.003
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.997	0.003
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.003
M10.99 Gout, unspecified (Site unspecified)	0.000	0.997	0.003
T36.9 Systemic antibiotic, unspecified	0.000	0.997	0.003
T36.8 Other systemic antibiotics	0.000	0.997	0.003
T36.7 Antifungal antibiotics, systemically used	0.000	0.997	0.003
T36.6 Rifamycins	0.000	0.997	0.003
T36.5 Aminoglycosides	0.000	0.997	0.003
T36.4 Tetracyclines	0.000	0.997	0.003
T36.3 Macrolides	0.000	0.997	0.003
T36.2 Chloramphenicol group	0.000	0.997	0.003
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.997	0.003
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.997	0.003
F34.1 Dysthymia	0.000	0.997	0.002
H52.3 Anisometropia and aniseikonia	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.003
H50.5 Heterophoria	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.002
T48.5 Anti-common-cold drugs	0.000	0.997	0.002
T48.4 Expectorants	0.000	0.997	0.002
T48.3 Antitussives	0.000	0.997	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.002
T48.0 Oxytocic drugs	0.000	0.997	0.002
H33.2 Serous retinal detachment	0.000	0.997	0.003
C77.2 Intra-abdominal lymph nodes	0.003	0.997	0.000
K30 Dyspepsia	0.000	0.997	0.003
T36.0 Penicillins	0.000	0.997	0.002
G90 Disorders of autonomic nervous system	0.000	0.997	0.003
M10.93 Gout, unspecified (Forearm)	0.000	0.997	0.003
Z34.8 Supervision of other normal pregnancy	0.000	0.997	0.003
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.997	0.002
N41.0 Acute prostatitis	0.000	0.997	0.003
M10.96 Gout, unspecified (Lower leg)	0.000	0.997	0.003
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.997	0.003
T39.4 Antirheumatics, not elsewhere classified	0.000	0.997	0.002
T39.2 Pyrazolone derivatives	0.000	0.997	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.997	0.002
H50.4 Other and unspecified heterotropia	0.002	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.997	0.002
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.997	0.002
T47.7 Emetics	0.000	0.997	0.002
T47.6 Antidiarrhoeal drugs	0.000	0.997	0.002
T47.5 Digestants	0.000	0.997	0.002
T47.4 Other laxatives	0.000	0.997	0.002
T47.3 Saline and osmotic laxatives	0.000	0.997	0.002
T47.2 Stimulant laxatives	0.000	0.997	0.002
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.002
G91.0 Communicating hydrocephalus	0.000	0.997	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.002
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
M10.98 Gout, unspecified (Other)	0.000	0.997	0.002
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.997	0.002
M10.92 Gout, unspecified (Upper arm)	0.000	0.997	0.002
M10.91 Gout, unspecified (Shoulder region)	0.000	0.997	0.002
H42.8 Glaucoma in other diseases classified elsewhere	0.002	0.997	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.002	0.997	0.000
H50.6 Mechanical strabismus	0.002	0.997	0.000
H50.3 Intermittent heterotropia	0.002	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.997	0.002
G90.2 Horner's syndrome	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
H50.8 Other specified strabismus	0.002	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.998	0.002
T39.0 Salicylates	0.000	0.998	0.002
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.998	0.002
G91.8 Other hydrocephalus	0.000	0.998	0.002
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.002	0.998	0.000
M10.94 Gout, unspecified (Hand)	0.000	0.998	0.002
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.002	0.998	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
G90.8 Other disorders of autonomic nervous system	0.000	0.998	0.002
G90.4 Autonomic dysreflexia	0.000	0.998	0.002
G90.1 Familial dysautonomia [Riley-Day]	0.000	0.998	0.002
M10.90 Gout, unspecified (Multiple sites)	0.000	0.998	0.002
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.000	0.998	0.002
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
V18 Pedal cyclist injured in noncollision transport accident	0.002	0.998	0.000
Z34.0 Supervision of normal first pregnancy	0.000	0.998	0.002
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.998	0.002
T40.8 Lysergide [LSD]	0.000	0.998	0.002
T40.7 Cannabis (derivatives)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations