TreeWAS – Variant ID: rs6698843

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.999	0.001	0.000
E78.5 Hyperlipidaemia, unspecified	0.999	0.001	0.000
E78.1 Pure hyperglyceridaemia	0.865	0.135	0.000
E78.6 Lipoprotein deficiency	0.816	0.184	0.000
E78.4 Other hyperlipidaemia	0.791	0.209	0.000
E78.8 Other disorders of lipoprotein metabolism	0.782	0.218	0.000
E78.3 Hyperchylomicronaemia	0.726	0.274	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.665	0.335	0.000
E78.2 Mixed hyperlipidaemia	0.512	0.488	0.000
E70-E90 Metabolic disorders	0.147	0.853	0.000
E87.7 Fluid overload	0.138	0.862	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.138	0.862	0.000
E72 Other disorders of amino-acid metabolism	0.122	0.878	0.000
E87.6 Hypokalaemia	0.119	0.881	0.000
E77 Disorders of glycoprotein metabolism	0.115	0.885	0.000
E83 Disorders of mineral metabolism	0.113	0.887	0.000
E83.4 Disorders of magnesium metabolism	0.112	0.888	0.000
E84 Cystic fibrosis	0.108	0.892	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.108	0.892	0.000
E76 Disorders of glycosaminoglycan metabolism	0.105	0.894	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.105	0.894	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.105	0.894	0.000
E72.0 Disorders of amino-acid transport	0.104	0.896	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.103	0.897	0.000
E87.4 Mixed disorder of acid-base balance	0.099	0.901	0.000
E87.0 Hyperosmolality and hypernatraemia	0.099	0.901	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.098	0.902	0.000
E70 Disorders of aromatic amino-acid metabolism	0.098	0.902	0.000
E79 Disorders of purine and pyrimidine metabolism	0.093	0.906	0.000
E77.8 Other disorders of glycoprotein metabolism	0.093	0.907	0.000
E74 Other disorders of carbohydrate metabolism	0.092	0.908	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.088	0.912	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.088	0.912	0.000
E72.5 Disorders of glycine metabolism	0.088	0.912	0.000
E72.4 Disorders of ornithine metabolism	0.088	0.912	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.088	0.912	0.000
E72.2 Disorders of urea cycle metabolism	0.088	0.912	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.088	0.912	0.000
E88 Other metabolic disorders	0.087	0.913	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.087	0.913	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.086	0.914	0.000
E87.3 Alkalosis	0.086	0.914	0.000
E87.2 Acidosis	0.083	0.917	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.083	0.917	0.000
E77.1 Defects in glycoprotein degradation	0.083	0.917	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.083	0.917	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.083	0.917	0.000
E83.8 Other disorders of mineral metabolism	0.081	0.919	0.000
E83.2 Disorders of zinc metabolism	0.081	0.919	0.000
E83.0 Disorders of copper metabolism	0.081	0.919	0.000
E84.9 Cystic fibrosis, unspecified	0.080	0.920	0.000
E89.3 Postprocedural hypopituitarism	0.079	0.921	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.079	0.921	0.000
E75.2 Other sphingolipidosis	0.078	0.922	0.000
E84.8 Cystic fibrosis with other manifestations	0.078	0.922	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.078	0.922	0.000
E71.3 Disorders of fatty-acid metabolism	0.076	0.924	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.076	0.924	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.076	0.924	0.000
E71.0 Maple-syrup-urine disease	0.076	0.924	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.076	0.924	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.076	0.924	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.076	0.924	0.000
E76.2 Other mucopolysaccharidoses	0.076	0.924	0.000
E76.1 Mucopolysaccharidosis, type II	0.076	0.924	0.000
E76.0 Mucopolysaccharidosis, type I	0.076	0.924	0.000
E73 Lactose intolerance	0.074	0.925	0.000
E89.1 Postprocedural hypoinsulinaemia	0.075	0.925	0.000
E75.6 Lipid storage disorder, unspecified	0.074	0.926	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.074	0.926	0.000
E75.3 Sphingolipidosis, unspecified	0.074	0.926	0.000
E75.1 Other gangliosidosis	0.074	0.926	0.000
E75.0 GM2 gangliosidosis	0.074	0.926	0.000
E88.2 Lipomatosis, not elsewhere classified	0.072	0.928	0.000
E88.3 Tumour lysis syndrome	0.071	0.929	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.071	0.929	0.000
E89.5 Postprocedural testicular hypofunction	0.071	0.929	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.070	0.929	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.070	0.929	0.000
E70.2 Disorders of tyrosine metabolism	0.070	0.929	0.000
E70.1 Other hyperphenylalaninaemias	0.070	0.929	0.000
E70.0 Classical phenylketonuria	0.070	0.929	0.000
E89.4 Postprocedural ovarian failure	0.070	0.930	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.069	0.931	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.068	0.932	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.067	0.933	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.067	0.933	0.000
E79.1 Lesch-Nyhan syndrome	0.067	0.933	0.000
E83.3 Disorders of phosphorus metabolism	0.067	0.933	0.000
E80.6 Other disorders of bilirubin metabolism	0.067	0.933	0.000
E89.2 Postprocedural hypoparathyroidism	0.067	0.933	0.000
E75.5 Other lipid storage disorders	0.066	0.933	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.066	0.934	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.066	0.934	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.066	0.934	0.000
E74.2 Disorders of galactose metabolism	0.066	0.934	0.000
E74.1 Disorders of fructose metabolism	0.066	0.934	0.000
E74.0 Glycogen storage disease	0.066	0.934	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.065	0.935	0.000
E80.1 Porphyria cutanea tarda	0.064	0.936	0.000
E70.3 Albinism	0.063	0.937	0.000
E80.5 Crigler-Najjar syndrome	0.062	0.937	0.000
E80.3 Defects of catalase and peroxydase	0.062	0.937	0.000
E80.0 Hereditary erythropoietic porphyria	0.062	0.937	0.000
E83.5 Disorders of calcium metabolism	0.062	0.938	0.000
E80.2 Other porphyria	0.062	0.938	0.000
E89.0 Postprocedural hypothyroidism	0.060	0.940	0.000
E85 Amyloidosis	0.059	0.941	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.059	0.941	0.000
E88.9 Metabolic disorder, unspecified	0.059	0.941	0.000
I25.1 Atherosclerotic heart disease	0.058	0.942	0.000
R53 Malaise and fatigue	0.057	0.943	0.000
I25.2 Old myocardial infarction	0.057	0.943	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.056	0.944	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.055	0.944	0.000
I25 Chronic ischaemic heart disease	0.055	0.945	0.000
E88.8 Other specified metabolic disorders	0.054	0.946	0.000
E73.8 Other lactose intolerance	0.053	0.946	0.000
E73.1 Secondary lactase deficiency	0.053	0.946	0.000
E73.0 Congenital lactase deficiency	0.053	0.946	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.053	0.947	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.048	0.952	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.042	0.957	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.042	0.957	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.042	0.957	0.000
E86 Volume depletion	0.041	0.959	0.000
E85.8 Other amyloidosis	0.040	0.960	0.000
I25.6 Silent myocardial ischaemia	0.039	0.961	0.000
E85.3 Secondary systemic amyloidosis	0.037	0.963	0.000
E85.4 Organ-limited amyloidosis	0.036	0.963	0.000
I35.0 Aortic (valve) stenosis	0.033	0.967	0.000
I25.4 Coronary artery aneurysm	0.031	0.969	0.000
E85.9 Amyloidosis, unspecified	0.029	0.971	0.000
I25.5 Ischaemic cardiomyopathy	0.029	0.971	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.028	0.971	0.000
E73.9 Lactose intolerance, unspecified	0.022	0.977	0.001
Y85.9 Sequelae of other and unspecified transport accidents	0.019	0.981	0.000
E80.4 Gilbert's syndrome	0.018	0.982	0.000
I25.3 Aneurysm of heart	0.018	0.982	0.000
Y85 Sequelae of transport accidents	0.018	0.982	0.000
C44.6 Skin of upper limb, including shoulder	0.000	0.983	0.017
E04.9 Non-toxic goitre, unspecified	0.017	0.983	0.000
Y85.0 Sequelae of motor-vehicle accident	0.016	0.984	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.016	0.984	0.000
Y86 Sequelae of other accidents	0.015	0.985	0.000
T91 Sequelae of injuries of neck and trunk	0.013	0.987	0.000
Y88 Sequelae of surgical and medical care as external cause	0.013	0.987	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.013	0.987	0.000
E87.5 Hyperkalaemia	0.013	0.987	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.012	0.988	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.012	0.988	0.000
T93 Sequelae of injuries of lower limb	0.012	0.988	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.012	0.988	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.012	0.988	0.000
Y89 Sequelae of other external causes	0.012	0.988	0.000
T91.3 Sequelae of injury of spinal cord	0.012	0.988	0.000
T93.0 Sequelae of open wound of lower limb	0.011	0.989	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.011	0.989	0.000
T92 Sequelae of injuries of upper limb	0.011	0.989	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.011	0.989	0.000
T95 Sequelae of burns, corrosions and frostbite	0.011	0.989	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.011	0.989	0.000
Z95.1 Presence of aortocoronary bypass graft	0.011	0.989	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.010	0.990	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.010	0.990	0.000
T93.1 Sequelae of fracture of femur	0.010	0.990	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.010	0.990	0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.010	0.990	0.000
T94.1 Sequelae of injuries, not specified by body region	0.010	0.990	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.010	0.990	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.010	0.990	0.000
Y87.1 Sequelae of assault	0.009	0.990	0.000
Y87.0 Sequelae of intentional self-harm	0.009	0.990	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.009	0.991	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.009	0.991	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.009	0.991	0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.009	0.991	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.009	0.991	0.000
T91.1 Sequelae of fracture of spine	0.009	0.991	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.009	0.991	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.009	0.991	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.009	0.991	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.009	0.991	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.009	0.991	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.009	0.991	0.000
Y87.2 Sequelae of events of undetermined intent	0.009	0.991	0.000
Y89.9 Sequelae of unspecified external cause	0.009	0.991	0.000
T92.0 Sequelae of open wound of upper limb	0.009	0.991	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.009	0.991	0.000
Y89.1 Sequelae of war operations	0.008	0.991	0.000
Y89.0 Sequelae of legal intervention	0.008	0.991	0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.008	0.992	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.008	0.992	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.008	0.992	0.000
Z95.0 Presence of cardiac pacemaker	0.008	0.992	0.000
T93.2 Sequelae of other fractures of lower limb	0.008	0.992	0.000
T45.5 Anticoagulants	0.008	0.992	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.008	0.992	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.008	0.992	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.008	0.992	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.008	0.992	0.000
I20.9 Angina pectoris, unspecified	0.008	0.992	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.992	0.008
D16.4 Bones of skull and face	0.008	0.992	0.000
D16 Benign neoplasm of bone and articular cartilage	0.008	0.992	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.008	0.992	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.008	0.992	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.008	0.992	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.008	0.992	0.000
D16.1 Short bones of upper limb	0.008	0.992	0.000
G03.9 Meningitis, unspecified	0.008	0.992	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.007	0.993	0.000
T50.1 Loop [high-ceiling] diuretics	0.007	0.993	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.007	0.993	0.000
D16.5 Lower jaw bone	0.007	0.993	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.007	0.993	0.000
T50.4 Drugs affecting uric acid metabolism	0.007	0.993	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.007	0.993	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.993	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.007	0.993	0.000
D16.0 Scapula and long bones of upper limb	0.007	0.993	0.000
T50.8 Diagnostic agents	0.007	0.993	0.000
T36 Poisoning by systemic antibiotics	0.007	0.993	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.007	0.993	0.000
T92.1 Sequelae of fracture of arm	0.007	0.993	0.000
T45.2 Vitamins, not elsewhere classified	0.007	0.993	0.000
T98 Sequelae of other and unspecified effects of external causes	0.006	0.993	0.000
D16.6 Vertebral column	0.007	0.993	0.000
T50.7 Analeptics and opioid receptor antagonists	0.006	0.993	0.000
T50.5 Appetite depressants	0.006	0.993	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.006	0.993	0.000
T50.0 Mineralocorticoids and their antagonists	0.006	0.993	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.007	0.993	0.000
C71.2 Temporal lobe	0.006	0.994	0.000
D16.2 Long bones of lower limb	0.006	0.994	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.006	0.994	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
E83.1 Disorders of iron metabolism	0.006	0.994	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.006	0.994	0.000
D16.3 Short bones of lower limb	0.006	0.994	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
M13.93 Arthritis, unspecified (Forearm)	0.006	0.994	0.000
T46.1 Calcium-channel blockers	0.006	0.994	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.006	0.994	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.006	0.994	0.000
D16.8 Pelvic bones, sacrum and coccyx	0.006	0.994	0.000
D16.7 Ribs, sternum and clavicle	0.006	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.994	0.000
T36.0 Penicillins	0.006	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.006	0.994	0.000
T45.8 Other primarily systemic and haematological agents	0.006	0.994	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.006	0.994	0.000
T45.6 Fibrinolysis-affecting drugs	0.006	0.994	0.000
T45.4 Iron and its compounds	0.006	0.994	0.000
T45.3 Enzymes, not elsewhere classified	0.006	0.994	0.000
G03 Meningitis due to other and unspecified causes	0.006	0.994	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.006	0.994	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.005	0.994	0.000
T36.3 Macrolides	0.006	0.994	0.000
T47.2 Stimulant laxatives	0.006	0.994	0.000
T47.6 Antidiarrhoeal drugs	0.006	0.994	0.000
T87.6 Other and unspecified complications of amputation stump	0.000	0.994	0.006
M13.9 Arthritis, unspecified	0.006	0.994	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.005	0.994	0.000
I35 Nonrheumatic aortic valve disorders	0.006	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.005	0.994	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.994	0.000
N17.9 Acute renal failure, unspecified	0.006	0.994	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.005	0.994	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.006	0.994	0.000
T36.4 Tetracyclines	0.005	0.995	0.000
T38.1 Thyroid hormones and substitutes	0.005	0.995	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.995	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.005	0.995	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.995	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.005	0.995	0.000
T44.0 Anticholinesterase agents	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
T47.4 Other laxatives	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.005	0.995	0.000
T36.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
T36.8 Other systemic antibiotics	0.005	0.995	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
T36.6 Rifamycins	0.005	0.995	0.000
T36.5 Aminoglycosides	0.005	0.995	0.000
T36.2 Chloramphenicol group	0.005	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.005	0.995	0.000
D16.9 Bone and articular cartilage, unspecified	0.005	0.995	0.000
T98.2 Sequelae of certain early complications of trauma	0.005	0.995	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.005	0.995	0.000
T38.5 Other oestrogens and progestogens	0.005	0.995	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.005	0.995	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.005	0.995	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.005	0.995	0.000
T38.9 Other and unspecified hormone antagonists	0.005	0.995	0.000
T38.7 Androgens and anabolic congeners	0.005	0.995	0.000
T38.4 Oral contraceptives	0.005	0.995	0.000
T38.2 Antithyroid drugs	0.005	0.995	0.000
T38.0 Glucocorticoids and synthetic analogues	0.005	0.995	0.000
T42.1 Iminostilbenes	0.005	0.995	0.000
T45.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.004	0.995	0.000
M13.94 Arthritis, unspecified (Hand)	0.005	0.995	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.005	0.995	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.005	0.995	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.005	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.995	0.000
T48.5 Anti-common-cold drugs	0.004	0.995	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.005	0.995	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.004	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.995	0.000
T48.4 Expectorants	0.004	0.995	0.000
T48.3 Antitussives	0.004	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.995	0.000
T48.0 Oxytocic drugs	0.004	0.995	0.000
G06.1 Intraspinal abscess and granuloma	0.004	0.995	0.000
G03.8 Meningitis due to other specified causes	0.004	0.996	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.004	0.996	0.000
G03.1 Chronic meningitis	0.004	0.996	0.000
G03.0 Nonpyogenic meningitis	0.004	0.996	0.000
I20-I25 Ischaemic heart diseases	0.004	0.996	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.004	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
T41.5 Therapeutic gases	0.004	0.996	0.000
T41.4 Anaesthetic, unspecified	0.004	0.996	0.000
T41.3 Local anaesthetics	0.004	0.996	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
T41.1 Intravenous anaesthetics	0.004	0.996	0.000
T41.0 Inhaled anaesthetics	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.004	0.996	0.000
C71.8 Overlapping lesion of brain	0.004	0.996	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.004	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.996	0.000
T37.5 Antiviral drugs	0.004	0.996	0.000
T37.4 Anthelminthics	0.004	0.996	0.000
T37.3 Other antiprotozoal drugs	0.004	0.996	0.000
T37.1 Antimycobacterial drugs	0.004	0.996	0.000
T37.0 Sulphonamides	0.004	0.996	0.000
T49.9 Topical agent, unspecified	0.004	0.996	0.000
T49.8 Other topical agents	0.004	0.996	0.000
T49.7 Dental drugs, topically applied	0.004	0.996	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.004	0.996	0.000
T49.5 Ophthalmological drugs and preparations	0.004	0.996	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.004	0.996	0.000
T49.3 Emollients, demulcents and protectants	0.004	0.996	0.000
T49.2 Local astringents and local detergents	0.004	0.996	0.000
T49.1 Antipruritics	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
M13.98 Arthritis, unspecified (Other)	0.004	0.996	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
I35.9 Aortic valve disorder, unspecified	0.004	0.996	0.000
C71 Malignant neoplasm of brain	0.004	0.996	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.004	0.996	0.000
T42.3 Barbiturates	0.004	0.996	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.004	0.996	0.000
G06.0 Intracranial abscess and granuloma	0.004	0.996	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.004	0.996	0.000
M86.6 Other chronic osteomyelitis	0.004	0.996	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.996	0.004
I35.8 Other aortic valve disorders	0.004	0.996	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.004	0.996	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.004	0.996	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
T90 Sequelae of injuries of head	0.004	0.996	0.000
T39.0 Salicylates	0.004	0.996	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.004	0.996	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.004	0.996	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.996	0.001
G09 Sequelae of inflammatory diseases of central nervous system	0.004	0.996	0.000
I20 Angina pectoris	0.004	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.003	0.996	0.000
T39.2 Pyrazolone derivatives	0.003	0.996	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.003	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.996	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.003	0.996	0.000
Z95.3 Presence of xenogenic heart valve	0.003	0.996	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.003	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
T90.8 Sequelae of other specified injuries of head	0.003	0.997	0.000
I23 Certain current complications following acute myocardial infarction	0.003	0.997	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.003	0.997	0.000
C71.4 Occipital lobe	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
T40.3 Methadone	0.003	0.997	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.003	0.997	0.000
C71.5 Cerebral ventricle	0.003	0.997	0.000
C71.6 Cerebellum	0.003	0.997	0.000
I22 Subsequent myocardial infarction	0.003	0.997	0.000
C71.3 Parietal lobe	0.003	0.997	0.000
S89.9 Unspecified injury of lower leg	0.003	0.997	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.003	0.997	0.000
G04.1 Tropical spastic paraplegia	0.003	0.997	0.000
G04.0 Acute disseminated encephalitis	0.003	0.997	0.000
M86.68 Other chronic osteomyelitis (Other)	0.003	0.997	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.003	0.997	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.003	0.997	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.003	0.997	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.003	0.997	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.003	0.997	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.003	0.997	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.003	0.997	0.000
C67.8 Overlapping lesion of bladder	0.003	0.997	0.000
G00 Bacterial meningitis, not elsewhere classified	0.003	0.997	0.000
G06.2 Extradural and subdural abscess, unspecified	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
T90.3 Sequelae of injury of cranial nerves	0.003	0.997	0.000
C67.5 Bladder neck	0.003	0.997	0.000
C71.7 Brain stem	0.003	0.997	0.000
T42.4 Benzodiazepines	0.003	0.997	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.003	0.997	0.000
T40.1 Heroin	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.997	0.000
T40.8 Lysergide [LSD]	0.003	0.997	0.000
T40.7 Cannabis (derivatives)	0.003	0.997	0.000
T40.0 Opium	0.003	0.997	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.003	0.997	0.000
S42.30 Fracture of shaft of humerus (closed)	0.003	0.997	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.003	0.997	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.997	0.003
C71.9 Brain, unspecified	0.003	0.997	0.000
D13.2 Duodenum	0.003	0.997	0.000
T40.5 Cocaine	0.003	0.997	0.000
N17 Acute renal failure	0.003	0.997	0.000
T90.5 Sequelae of intracranial injury	0.003	0.997	0.000
T90.0 Sequelae of superficial injury of head	0.003	0.997	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
G02.1 Meningitis in mycoses	0.003	0.997	0.000
K07.3 Anomalies of tooth position	0.003	0.997	0.000
T40.6 Other and unspecified narcotics	0.003	0.997	0.000
T90.4 Sequelae of injury of eye and orbit	0.003	0.997	0.000
F30.0 Hypomania	0.003	0.997	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.002	0.997	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.002	0.997	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.002	0.997	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.002	0.997	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.002	0.997	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.002	0.997	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.002	0.997	0.000
E04 Other non-toxic goitre	0.003	0.997	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.003	0.997	0.000
G00.9 Bacterial meningitis, unspecified	0.002	0.997	0.000
I23.8 Other current complications following acute myocardial infarction	0.002	0.997	0.000
C21.1 Anal canal	0.003	0.997	0.000
M86.9 Osteomyelitis, unspecified	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
C81.9 Hodgkin's disease, unspecified	0.003	0.997	0.000
C81.1 Nodular sclerosis	0.003	0.997	0.000
G00.8 Other bacterial meningitis	0.002	0.997	0.000
G00.3 Staphylococcal meningitis	0.002	0.997	0.000
G00.0 Haemophilus meningitis	0.002	0.997	0.000
S92.50 Fracture of other toe (closed)	0.002	0.997	0.000
C67.2 Lateral wall of bladder	0.003	0.997	0.000
T90.1 Sequelae of open wound of head	0.002	0.997	0.000
F30 Manic episode	0.002	0.997	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.002	0.998	0.000
N17.8 Other acute renal failure	0.002	0.998	0.000
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.002	0.998	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.002	0.998	0.000
G00.2 Streptococcal meningitis	0.002	0.998	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.002	0.998	0.000
M86 Osteomyelitis	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
N17.2 Acute renal failure with medullary necrosis	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.002	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
F30.1 Mania without psychotic symptoms	0.002	0.998	0.000
N75.0 Cyst of Bartholin's gland	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations