TreeWAS – Variant ID: rs6711016

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.115	0.885	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.115	0.885	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.111	0.889	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.111	0.889	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.106	0.894	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.105	0.895	0.000
T42.4 Benzodiazepines	0.101	0.899	0.000
T45.0 Antiallergic and antiemetic drugs	0.101	0.899	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.098	0.902	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.096	0.904	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.095	0.905	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.094	0.906	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.093	0.907	0.000
T43.6 Psychostimulants with abuse potential	0.090	0.910	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.089	0.911	0.000
T40.2 Other opioids	0.089	0.911	0.000
T42.0 Hydantoin derivatives	0.089	0.911	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.089	0.911	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.088	0.912	0.000
T36 Poisoning by systemic antibiotics	0.086	0.914	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.083	0.916	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.082	0.918	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.082	0.918	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.082	0.918	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.082	0.918	0.000
T42.3 Barbiturates	0.082	0.918	0.000
T42.2 Succinimides and oxazolidinediones	0.082	0.918	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.081	0.919	0.000
T43.9 Psychotropic drug, unspecified	0.080	0.920	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.080	0.920	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.080	0.920	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.078	0.922	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.076	0.924	0.000
T50.8 Diagnostic agents	0.076	0.924	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.075	0.924	0.000
T45.8 Other primarily systemic and haematological agents	0.075	0.924	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.075	0.924	0.000
T45.6 Fibrinolysis-affecting drugs	0.075	0.924	0.000
T45.4 Iron and its compounds	0.075	0.924	0.000
T45.3 Enzymes, not elsewhere classified	0.075	0.924	0.000
T45.5 Anticoagulants	0.073	0.927	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.072	0.927	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.072	0.928	0.000
T42.1 Iminostilbenes	0.071	0.929	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.071	0.929	0.000
T50.4 Drugs affecting uric acid metabolism	0.071	0.929	0.000
T40.6 Other and unspecified narcotics	0.070	0.929	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.069	0.931	0.000
T40.8 Lysergide [LSD]	0.069	0.931	0.000
T40.7 Cannabis (derivatives)	0.069	0.931	0.000
T40.5 Cocaine	0.069	0.931	0.000
T40.3 Methadone	0.069	0.931	0.000
T40.1 Heroin	0.069	0.931	0.000
T40.0 Opium	0.069	0.931	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.068	0.932	0.000
T45.2 Vitamins, not elsewhere classified	0.068	0.932	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.067	0.932	0.000
T50.7 Analeptics and opioid receptor antagonists	0.067	0.932	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.067	0.932	0.000
T50.5 Appetite depressants	0.067	0.932	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.067	0.932	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.067	0.932	0.000
T50.1 Loop [high-ceiling] diuretics	0.067	0.932	0.000
T50.0 Mineralocorticoids and their antagonists	0.067	0.932	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.067	0.933	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.067	0.933	0.000
T47.7 Emetics	0.067	0.933	0.000
T47.6 Antidiarrhoeal drugs	0.067	0.933	0.000
T47.5 Digestants	0.067	0.933	0.000
T47.4 Other laxatives	0.067	0.933	0.000
T47.3 Saline and osmotic laxatives	0.067	0.933	0.000
T47.2 Stimulant laxatives	0.067	0.933	0.000
T47.0 Histamine H(2)-receptor antagonists	0.067	0.933	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.065	0.935	0.000
T36.3 Macrolides	0.065	0.935	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.064	0.936	0.000
T48.5 Anti-common-cold drugs	0.064	0.936	0.000
T48.4 Expectorants	0.064	0.936	0.000
T48.3 Antitussives	0.064	0.936	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.064	0.936	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.064	0.936	0.000
T48.0 Oxytocic drugs	0.064	0.936	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.064	0.936	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.064	0.936	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.064	0.936	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.064	0.936	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.064	0.936	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.064	0.936	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.064	0.936	0.000
T44.0 Anticholinesterase agents	0.064	0.936	0.000
T36.0 Penicillins	0.062	0.938	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.062	0.938	0.000
T36.9 Systemic antibiotic, unspecified	0.062	0.938	0.000
T36.8 Other systemic antibiotics	0.062	0.938	0.000
T36.7 Antifungal antibiotics, systemically used	0.062	0.938	0.000
T36.6 Rifamycins	0.062	0.938	0.000
T36.5 Aminoglycosides	0.062	0.938	0.000
T36.4 Tetracyclines	0.062	0.938	0.000
T36.2 Chloramphenicol group	0.062	0.938	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.062	0.938	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.059	0.941	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.059	0.941	0.000
T37.5 Antiviral drugs	0.059	0.941	0.000
T37.4 Anthelminthics	0.059	0.941	0.000
T37.3 Other antiprotozoal drugs	0.059	0.941	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.059	0.941	0.000
T37.1 Antimycobacterial drugs	0.059	0.941	0.000
T37.0 Sulphonamides	0.059	0.941	0.000
T41.5 Therapeutic gases	0.059	0.941	0.000
T41.4 Anaesthetic, unspecified	0.059	0.941	0.000
T41.3 Local anaesthetics	0.059	0.941	0.000
T41.2 Other and unspecified general anaesthetics	0.059	0.941	0.000
T41.1 Intravenous anaesthetics	0.059	0.941	0.000
T41.0 Inhaled anaesthetics	0.059	0.941	0.000
T49.9 Topical agent, unspecified	0.059	0.941	0.000
T49.8 Other topical agents	0.059	0.941	0.000
T49.7 Dental drugs, topically applied	0.059	0.941	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.059	0.941	0.000
T49.5 Ophthalmological drugs and preparations	0.059	0.941	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.059	0.941	0.000
T49.3 Emollients, demulcents and protectants	0.059	0.941	0.000
T49.2 Local astringents and local detergents	0.059	0.941	0.000
T49.1 Antipruritics	0.059	0.941	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.059	0.941	0.000
T38.9 Other and unspecified hormone antagonists	0.058	0.942	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.058	0.942	0.000
T38.7 Androgens and anabolic congeners	0.058	0.942	0.000
T38.5 Other oestrogens and progestogens	0.058	0.942	0.000
T38.4 Oral contraceptives	0.058	0.942	0.000
T38.2 Antithyroid drugs	0.058	0.942	0.000
T38.0 Glucocorticoids and synthetic analogues	0.058	0.942	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.058	0.942	0.000
T38.1 Thyroid hormones and substitutes	0.055	0.945	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.054	0.946	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.052	0.948	0.000
T39.4 Antirheumatics, not elsewhere classified	0.052	0.948	0.000
T39.2 Pyrazolone derivatives	0.052	0.948	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.046	0.953	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.045	0.955	0.000
T43.2 Other and unspecified antidepressants	0.045	0.955	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.044	0.955	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.044	0.955	0.000
T46.7 Peripheral vasodilators	0.044	0.955	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.044	0.955	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.044	0.955	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.044	0.955	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.044	0.955	0.000
T40.4 Other synthetic narcotics	0.044	0.956	0.000
T46.1 Calcium-channel blockers	0.042	0.958	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.041	0.959	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.034	0.966	0.000
T39.0 Salicylates	0.028	0.971	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.972	0.028
M23.8 Other internal derangements of knee	0.000	0.982	0.018
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.982	0.018
F60 Specific personality disorders	0.014	0.986	0.000
F60.3 Emotionally unstable personality disorder	0.014	0.986	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.986	0.014
G57.6 Lesion of plantar nerve	0.000	0.986	0.014
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.987	0.013
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.987	0.013
F60.7 Dependent personality disorder	0.012	0.987	0.000
F60.9 Personality disorder, unspecified	0.012	0.988	0.000
F60.8 Other specific personality disorders	0.012	0.988	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.988	0.011
T39.1 4-Aminophenol derivatives	0.011	0.989	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.989	0.011
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.989	0.011
F60.6 Anxious [avoidant] personality disorder	0.011	0.989	0.000
F60.5 Anankastic personality disorder	0.011	0.989	0.000
F60-F69 Disorders of adult personality and behaviour	0.011	0.989	0.000
F69 Unspecified disorder of adult personality and behaviour	0.011	0.989	0.000
F60.4 Histrionic personality disorder	0.010	0.989	0.000
F60.2 Dissocial personality disorder	0.010	0.989	0.000
F60.1 Schizoid personality disorder	0.010	0.989	0.000
F60.0 Paranoid personality disorder	0.010	0.989	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.990	0.010
F61 Mixed and other personality disorders	0.009	0.991	0.000
F68 Other disorders of adult personality and behaviour	0.008	0.992	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.008	0.992	0.000
F65 Disorders of sexual preference	0.008	0.992	0.000
F63 Habit and impulse disorders	0.008	0.992	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.008	0.992	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.008	0.992	0.000
F64 Gender identity disorders	0.007	0.993	0.000
Q60.0 Renal agenesis, unilateral	0.006	0.994	0.000
F62.9 Enduring personality change, unspecified	0.006	0.994	0.000
F62.8 Other enduring personality changes	0.006	0.994	0.000
F62.1 Enduring personality change after psychiatric illness	0.006	0.994	0.000
F62.0 Enduring personality change after catastrophic experience	0.006	0.994	0.000
F63.9 Habit and impulse disorder, unspecified	0.006	0.994	0.000
F63.8 Other habit and impulse disorders	0.006	0.994	0.000
F63.3 Trichotillomania	0.006	0.994	0.000
F63.2 Pathological stealing [kleptomania]	0.006	0.994	0.000
F63.1 Pathological fire-setting [pyromania]	0.006	0.994	0.000
F63.0 Pathological gambling	0.006	0.994	0.000
F65.9 Disorder of sexual preference, unspecified	0.006	0.994	0.000
F65.8 Other disorders of sexual preference	0.006	0.994	0.000
F65.6 Multiple disorders of sexual preference	0.006	0.994	0.000
F65.5 Sadomasochism	0.006	0.994	0.000
F65.4 Paedophilia	0.006	0.994	0.000
F65.3 Voyeurism	0.006	0.994	0.000
F65.2 Exhibitionism	0.006	0.994	0.000
F65.1 Fetishistic transvestism	0.006	0.994	0.000
F65.0 Fetishism	0.006	0.994	0.000
F66.9 Psychosexual development disorder, unspecified	0.006	0.994	0.000
F66.8 Other psychosexual development disorders	0.006	0.994	0.000
F66.2 Sexual relationship disorder	0.006	0.994	0.000
F66.1 Egodystonic sexual orientation	0.006	0.994	0.000
F66.0 Sexual maturation disorder	0.006	0.994	0.000
F68.8 Other specified disorders of adult personality and behaviour	0.006	0.994	0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.006	0.994	0.000
F68.0 Elaboration of physical symptoms for psychological reasons	0.006	0.994	0.000
Z82.3 Family history of stroke	0.006	0.994	0.000
F64.9 Gender identity disorder, unspecified	0.005	0.994	0.000
F64.8 Other gender identity disorders	0.005	0.994	0.000
F64.2 Gender identity disorder of childhood	0.005	0.994	0.000
F64.1 Dual-role transvestism	0.005	0.994	0.000
N90.7 Vulvar cyst	0.005	0.995	0.000
Q61.0 Congenital single renal cyst	0.005	0.995	0.000
Q61 Cystic kidney disease	0.005	0.995	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.005	0.995	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.995	0.005
F64.0 Transsexualism	0.005	0.995	0.000
Q61.3 Polycystic kidney, unspecified	0.005	0.995	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.005	0.995	0.000
G57 Mononeuropathies of lower limb	0.000	0.995	0.005
T63.4 Venom of other arthropods	0.005	0.995	0.000
Q61.5 Medullary cystic kidney	0.004	0.996	0.000
Q61.4 Renal dysplasia	0.004	0.996	0.000
Q60.2 Renal agenesis, unspecified	0.004	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.004	0.996	0.000
Y86 Sequelae of other accidents	0.004	0.996	0.000
Q61.8 Other cystic kidney diseases	0.004	0.996	0.000
Q61.1 Polycystic kidney, infantile type	0.004	0.996	0.000
Q60.6 Potter's syndrome	0.004	0.996	0.000
Q60.5 Renal hypoplasia, unspecified	0.004	0.996	0.000
Q60.4 Renal hypoplasia, bilateral	0.004	0.996	0.000
Q60.3 Renal hypoplasia, unilateral	0.004	0.996	0.000
Q60.1 Renal agenesis, bilateral	0.004	0.996	0.000
G57.8 Other mononeuropathies of lower limb	0.000	0.996	0.004
G57.5 Tarsal tunnel syndrome	0.000	0.996	0.004
G57.0 Lesion of sciatic nerve	0.000	0.996	0.004
M23 Internal derangement of knee	0.000	0.996	0.004
Q61.2 Polycystic kidney, adult type	0.004	0.996	0.000
M54.37 Sciatica (Lumbosacral region)	0.004	0.996	0.000
G57.4 Lesion of medial popliteal nerve	0.000	0.996	0.004
G57.2 Lesion of femoral nerve	0.000	0.996	0.004
Q61.9 Cystic kidney disease, unspecified	0.003	0.996	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.004	0.996	0.000
G57.1 Meralgia paraesthetica	0.000	0.996	0.003
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
M25.53 Pain in joint (Forearm)	0.000	0.997	0.003
M23.1 Discoid meniscus (congenital)	0.000	0.997	0.003
I08.8 Other multiple valve diseases	0.000	0.997	0.003
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.997	0.003
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
O34.1 Maternal care for tumour of corpus uteri	0.003	0.997	0.000
M23.5 Chronic instability of knee	0.000	0.997	0.003
T63 Toxic effect of contact with venomous animals	0.003	0.997	0.000
O32.8 Maternal care for other malpresentation of foetus	0.003	0.997	0.000
O32.4 Maternal care for high head at term	0.003	0.997	0.000
R03.1 Nonspecific low blood-pressure reading	0.003	0.997	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.003	0.997	0.000
O48 Prolonged pregnancy	0.003	0.997	0.000
O36.9 Maternal care for foetal problem, unspecified	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.000	0.997	0.003
G57.9 Mononeuropathy of lower limb, unspecified	0.000	0.997	0.003
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
O36.3 Maternal care for signs of foetal hypoxia	0.003	0.997	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.003	0.997	0.000
M23.9 Internal derangement of knee, unspecified	0.000	0.997	0.003
O02.1 Missed abortion	0.003	0.997	0.000
T20.2 Burn of second degree of head and neck	0.003	0.997	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.003	0.997	0.000
Q62.5 Duplication of ureter	0.003	0.997	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.003	0.997	0.000
M23.0 Cystic meniscus	0.000	0.997	0.003
M23.4 Loose body in knee	0.000	0.997	0.003
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.003	0.997	0.000
O34.6 Maternal care for abnormality of vagina	0.003	0.997	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.003	0.997	0.000
O34.0 Maternal care for congenital malformation of uterus	0.003	0.997	0.000
G57.3 Lesion of lateral popliteal nerve	0.000	0.997	0.002
O34.4 Maternal care for other abnormalities of cervix	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
O36 Maternal care for other known or suspected foetal problems	0.003	0.997	0.000
G24.9 Dystonia, unspecified	0.003	0.997	0.000
H74.4 Polyp of middle ear	0.000	0.997	0.003
O46 Antepartum haemorrhage, not elsewhere classified	0.003	0.997	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.002
M23.17 Discoid meniscus (congenital)-Capsular lig	0.000	0.997	0.002
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.000	0.997	0.002
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.002
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.002
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.002
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.002
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.000	0.997	0.002
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.002
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.997	0.002
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.997	0.002
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.997	0.002
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.002
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.002
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.002
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.997	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.997	0.003
O30 Multiple gestation	0.003	0.997	0.000
E07.9 Disorder of thyroid, unspecified	0.003	0.997	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.997	0.002
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.997	0.002
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.997	0.002
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.002
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.002
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.002
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.997	0.002
O32.3 Maternal care for face, brow and chin presentation	0.003	0.997	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.002	0.997	0.000
T63.8 Toxic effect of contact with other venomous animals	0.002	0.997	0.000
T63.6 Toxic effect of contact with other marine animals	0.002	0.997	0.000
T63.5 Toxic effect of contact with fish	0.002	0.997	0.000
T63.3 Venom of spider	0.002	0.997	0.000
T63.2 Venom of scorpion	0.002	0.997	0.000
T63.1 Venom of other reptiles	0.002	0.997	0.000
T63.0 Snake venom	0.002	0.997	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.002	0.997	0.000
M23.49 Loose body in knee-Unspec lig/men	0.000	0.997	0.002
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.997	0.000
Q64.4 Malformation of urachus	0.002	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.997	0.000
Q64.0 Epispadias	0.002	0.997	0.000
N36.9 Urethral disorder, unspecified	0.002	0.997	0.000
O46.9 Antepartum haemorrhage, unspecified	0.003	0.997	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.002
O36.6 Maternal care for excessive foetal growth	0.002	0.997	0.000
C20 Malignant neoplasm of rectum	0.003	0.997	0.000
I08 Multiple valve diseases	0.000	0.997	0.003
S52.80 Fracture of other parts of forearm (closed)	0.002	0.998	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.002	0.998	0.000
S31.1 Open wound of abdominal wall	0.002	0.998	0.000
N36 Other disorders of urethra	0.002	0.998	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.998	0.002
M00.94 Pyogenic arthritis, unspecified (Hand)	0.002	0.998	0.000
N36.0 Urethral fistula	0.002	0.998	0.000
O30.0 Twin pregnancy	0.002	0.998	0.000
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.002	0.998	0.000
O34.3 Maternal care for cervical incompetence	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.000	0.998	0.002
N36.8 Other specified disorders of urethra	0.002	0.998	0.000
O43 Placental disorders	0.002	0.998	0.000
O33 Maternal care for known or suspected disproportion	0.002	0.998	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.998	0.002
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.000	0.998	0.002
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.000	0.998	0.002
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.000	0.998	0.002
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.000	0.998	0.002
O42 Premature rupture of membranes	0.002	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.998	0.002
O32.6 Maternal care for compound presentation	0.002	0.998	0.000
O31 Complications specific to multiple gestation	0.002	0.998	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.002	0.998	0.000
O46.8 Other antepartum haemorrhage	0.002	0.998	0.000
M23.43 Loose body in knee-Med lig/oth men	0.000	0.998	0.002
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
O32.0 Maternal care for unstable lie	0.002	0.998	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.998	0.000
M23.07 Cystic meniscus-Capsular lig	0.000	0.998	0.002
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.998	0.002
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
M23.00 Cystic meniscus (Multiple sites)	0.000	0.998	0.002
M23.47 Loose body in knee-Capsular lig	0.000	0.998	0.002
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.998	0.002
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.998	0.002
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.998	0.002
N36.3 Prolapsed urethral mucosa	0.002	0.998	0.000
O36.1 Maternal care for other isoimmunisation	0.002	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
T20 Burn and corrosion of head and neck	0.002	0.998	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
O33.5 Maternal care for disproportion due to unusually large foetus	0.002	0.998	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.002	0.998	0.000
O36.2 Maternal care for hydrops foetalis	0.002	0.998	0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.002	0.998	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.002	0.998	0.000
K50.8 Other Crohn's disease	0.002	0.998	0.000
N36.2 Urethral caruncle	0.002	0.998	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.002	0.998	0.000
H34.2 Other retinal artery occlusions	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
J94.8 Other specified pleural conditions	0.000	0.998	0.002
O32.2 Maternal care for transverse and oblique lie	0.002	0.998	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
O30.9 Multiple gestation, unspecified	0.002	0.998	0.000
O30.8 Other multiple gestation	0.002	0.998	0.000
O30.2 Quadruplet pregnancy	0.002	0.998	0.000
O30.1 Triplet pregnancy	0.002	0.998	0.000
O43.0 Placental transfusion syndromes	0.002	0.998	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
M23.40 Loose body in knee-Mult sites	0.000	0.998	0.002
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
E07.8 Other specified disorders of thyroid	0.002	0.998	0.000
N36.1 Urethral diverticulum	0.002	0.998	0.000
M00.9 Pyogenic arthritis, unspecified	0.002	0.998	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.998	0.002
O41 Other disorders of amniotic fluid and membranes	0.002	0.998	0.000
M23.46 Loose body in knee-O/unsp lat men	0.000	0.998	0.002
S59.9 Unspecified injury of forearm	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
O45 Premature separation of placenta [abruptio placentae]	0.002	0.998	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
O16 Unspecified maternal hypertension	0.002	0.998	0.000
T56 Toxic effect of metals	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
K52.3 Indeterminate colitis	0.000	0.998	0.002
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.000	0.998	0.002
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
Q63.2 Ectopic kidney	0.002	0.998	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.002
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
O33.8 Maternal care for disproportion of other origin	0.002	0.998	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.002	0.998	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.002	0.998	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.002	0.998	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.002	0.998	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.002	0.998	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.002	0.998	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.002	0.998	0.000
O41.1 Infection of amniotic sac and membranes	0.002	0.998	0.000
O43.2 Morbidly adherent placenta	0.002	0.998	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
O31.8 Other complications specific to multiple gestation	0.002	0.998	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.002	0.998	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.002	0.998	0.000
O31.0 Papyraceous foetus	0.002	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.002	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.998	0.002
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.002	0.998	0.000
T56.8 Other metals	0.002	0.998	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.002	0.998	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
D09.0 Bladder	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
O43.8 Other placental disorders	0.002	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.000	0.998	0.002
T20.7 Corrosion of third degree of head and neck	0.002	0.998	0.000
T20.6 Corrosion of second degree of head and neck	0.002	0.998	0.000
T20.5 Corrosion of first degree of head and neck	0.002	0.998	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.002	0.998	0.000
T20.3 Burn of third degree of head and neck	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
O43.1 Malformation of placenta	0.002	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
O43.9 Placental disorder, unspecified	0.002	0.998	0.000
S13.1 Dislocation of cervical vertebra	0.002	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
N90.4 Leukoplakia of vulva	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations