TreeWAS – Variant ID: rs6722456

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I84.9 Unspecified haemorrhoids without complication	0.000	0.973	0.027
N83.2 Other and unspecified ovarian cysts	0.000	0.978	0.022
M20-M25 Other joint disorders	0.019	0.981	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.981	0.019
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.018	0.982	0.000
M23 Internal derangement of knee	0.018	0.982	0.000
M23.8 Other internal derangements of knee	0.018	0.982	0.000
M80-M85 Disorders of bone density and structure	0.018	0.982	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.018	0.982	0.000
M24 Other specific joint derangements	0.018	0.982	0.000
M20 Acquired deformities of fingers and toes	0.018	0.982	0.000
N83.0 Follicular cyst of ovary	0.000	0.983	0.017
M06 Other rheumatoid arthritis	0.017	0.983	0.000
M81 Osteoporosis without pathological fracture	0.017	0.983	0.000
M05-M14 Inflammatory polyarthropathies	0.017	0.983	0.000
M81.9 Osteoporosis, unspecified	0.017	0.983	0.000
M06.9 Rheumatoid arthritis, unspecified	0.016	0.984	0.000
M35 Other systemic involvement of connective tissue	0.016	0.984	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.016	0.984	0.000
M20.5 Other deformities of toe(s) (acquired)	0.016	0.984	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.984	0.016
N83.1 Corpus luteum cyst	0.000	0.984	0.016
M23.5 Chronic instability of knee	0.016	0.984	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.016	0.984	0.000
M84 Disorders of continuity of bone	0.016	0.984	0.000
M20.2 Hallux rigidus	0.016	0.984	0.000
M24.1 Other articular cartilage disorders	0.015	0.985	0.000
M35.0 Sicca syndrome [Sjogren]	0.015	0.985	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.015	0.985	0.000
M40-M43 Deforming dorsopathies	0.015	0.985	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.015	0.985	0.000
M06.0 Seronegative rheumatoid arthritis	0.014	0.985	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.014	0.986	0.000
M24.0 Loose body in joint	0.014	0.986	0.000
M80 Osteoporosis with pathological fracture	0.014	0.986	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.014	0.986	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.014	0.986	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.014	0.986	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.014	0.986	0.000
M34 Systemic sclerosis	0.014	0.986	0.000
M33 Dermatopolymyositis	0.014	0.986	0.000
M32 Systemic lupus erythematosus	0.014	0.986	0.000
M30 Polyarteritis nodosa and related conditions	0.014	0.986	0.000
M06.3 Rheumatoid nodule	0.014	0.986	0.000
N83.7 Haematoma of broad ligament	0.000	0.986	0.014
N83.6 Haematosalpinx	0.000	0.986	0.014
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.000	0.986	0.014
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.000	0.986	0.014
N83.3 Acquired atrophy of ovary and Fallopian tube	0.000	0.986	0.014
M65-M68 Disorders of synovium and tendon	0.014	0.986	0.000
M24.2 Disorder of ligament	0.013	0.986	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.013	0.986	0.000
M15-M19 Arthrosis	0.014	0.986	0.000
M25 Other joint disorders, not elsewhere classified	0.014	0.986	0.000
M85 Other disorders of bone density and structure	0.013	0.986	0.000
M23.9 Internal derangement of knee, unspecified	0.013	0.987	0.000
M23.1 Discoid meniscus (congenital)	0.013	0.987	0.000
M23.0 Cystic meniscus	0.013	0.987	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.013	0.987	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.013	0.987	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.013	0.987	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.013	0.987	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.013	0.987	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.013	0.987	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.013	0.987	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.000	0.987	0.013
M83 Adult osteomalacia	0.013	0.987	0.000
M82 Osteoporosis in diseases classified elsewhere	0.013	0.987	0.000
M45-M49 Spondylopathies	0.013	0.987	0.000
M31 Other necrotising vasculopathies	0.013	0.987	0.000
M21 Other acquired deformities of limbs	0.013	0.987	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.013	0.987	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.013	0.987	0.000
M07 Psoriatic and enteropathic arthropathies	0.013	0.987	0.000
M43 Other deforming dorsopathies	0.013	0.987	0.000
M23.4 Loose body in knee	0.013	0.987	0.000
M84.0 Malunion of fracture	0.013	0.987	0.000
M91-M94 Chondropathies	0.013	0.987	0.000
M60-M63 Disorders of muscles	0.013	0.987	0.000
M00-M03 Infectious arthropathies	0.013	0.987	0.000
M24.9 Joint derangement, unspecified	0.013	0.987	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.013	0.987	0.000
M24.7 Protrusio acetabuli	0.013	0.987	0.000
M24.6 Ankylosis of joint	0.013	0.987	0.000
M24.5 Contracture of joint	0.013	0.987	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.013	0.987	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.013	0.987	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.013	0.987	0.000
M86-M90 Other osteopathies	0.013	0.987	0.000
M81.4 Drug-induced osteoporosis	0.013	0.987	0.000
M81.98 Osteoporosis, unspecified (Other)	0.013	0.987	0.000
M17 Gonarthrosis [arthrosis of knee]	0.013	0.987	0.000
M06.8 Other specified rheumatoid arthritis	0.012	0.987	0.000
M06.4 Inflammatory polyarthropathy	0.012	0.987	0.000
M06.2 Rheumatoid bursitis	0.012	0.987	0.000
M06.1 Adult-onset Still's disease	0.012	0.987	0.000
M81.8 Other osteoporosis	0.012	0.987	0.000
M81.6 Localised osteoporosis [Lequesne]	0.012	0.987	0.000
M81.5 Idiopathic osteoporosis	0.012	0.987	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.012	0.987	0.000
M81.2 Osteoporosis of disuse	0.012	0.987	0.000
M81.1 Postoophorectomy osteoporosis	0.012	0.987	0.000
M81.0 Postmenopausal osteoporosis	0.012	0.987	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.012	0.987	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.012	0.987	0.000
M13 Other arthritis	0.012	0.987	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.013	0.987	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.012	0.987	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.012	0.988	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.012	0.988	0.000
M14 Arthropathies in other diseases classified elsewhere	0.012	0.988	0.000
M12 Other specific arthropathies	0.012	0.988	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.012	0.988	0.000
M08 Juvenile arthritis	0.012	0.988	0.000
S00-S09 Injuries to the head	0.012	0.988	0.000
M20.3 Other deformity of hallux (acquired)	0.012	0.988	0.000
M20.0 Deformity of finger(s)	0.012	0.988	0.000
M05 Seropositive rheumatoid arthritis	0.012	0.988	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.012	0.988	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.012	0.988	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.012	0.988	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.012	0.988	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.012	0.988	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.012	0.988	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.012	0.988	0.000
S06 Intracranial injury	0.012	0.988	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.012	0.988	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.012	0.988	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.012	0.988	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.012	0.988	0.000
J44 Other chronic obstructive pulmonary disease	0.012	0.988	0.000
M20.1 Hallux valgus (acquired)	0.012	0.988	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.012	0.988	0.000
M35.8 Other specified systemic involvement of connective tissue	0.012	0.988	0.000
M35.7 Hypermobility syndrome	0.012	0.988	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.012	0.988	0.000
M35.5 Multifocal fibrosclerosis	0.012	0.988	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.012	0.988	0.000
M35.2 Behcet's disease	0.012	0.988	0.000
M35.1 Other overlap syndromes	0.012	0.988	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.012	0.988	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.012	0.988	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.012	0.988	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.012	0.988	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.012	0.988	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.012	0.988	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.012	0.988	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.012	0.988	0.000
M84.9 Disorder of continuity of bone, unspecified	0.012	0.988	0.000
M84.8 Other disorders of continuity of bone	0.012	0.988	0.000
M84.4 Pathological fracture, not elsewhere classified	0.012	0.988	0.000
M84.3 Stress fracture, not elsewhere classified	0.012	0.988	0.000
M84.2 Delayed union of fracture	0.012	0.988	0.000
D48.5 Skin	0.012	0.988	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.012	0.988	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.012	0.988	0.000
M24.02 Loose body in joint (Upper arm)	0.011	0.988	0.000
M17.0 Primary gonarthrosis, bilateral	0.012	0.988	0.000
M06.34 Rheumatoid nodule (Hand)	0.011	0.988	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.011	0.989	0.000
S01 Open wound of head	0.011	0.989	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.011	0.989	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.011	0.989	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.011	0.989	0.000
M24.07 Loose body in joint (Ankle and foot)	0.011	0.989	0.000
D46 Myelodysplastic syndromes	0.011	0.989	0.000
M50-M54 Other dorsopathies	0.011	0.989	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.011	0.989	0.000
M24.18 Other articular cartilage disorders (Other)	0.011	0.989	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.011	0.989	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.011	0.989	0.000
M24.14 Other articular cartilage disorders (Hand)	0.011	0.989	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.011	0.989	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.011	0.989	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.011	0.989	0.000
M43.1 Spondylolisthesis	0.011	0.989	0.000
M25.7 Osteophyte	0.011	0.989	0.000
D41.4 Bladder	0.011	0.989	0.000
M17.1 Other primary gonarthrosis	0.011	0.989	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.011	0.989	0.000
M84.03 Malunion of fracture (Forearm)	0.011	0.989	0.000
M11 Other crystal arthropathies	0.011	0.989	0.000
M25.8 Other specified joint disorders	0.011	0.989	0.000
M42 Spinal osteochondrosis	0.011	0.989	0.000
M40 Kyphosis and lordosis	0.011	0.989	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.011	0.989	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.011	0.989	0.000
M23.3 Other meniscus derangements	0.011	0.989	0.000
M10 Gout	0.010	0.989	0.001
M80.9 Unspecified osteoporosis with pathological fracture	0.011	0.989	0.000
M66 Spontaneous rupture of synovium and tendon	0.011	0.989	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.011	0.989	0.000
M43.0 Spondylolysis	0.011	0.989	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.011	0.989	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.011	0.989	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.010	0.989	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.010	0.989	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.010	0.989	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.010	0.989	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.010	0.989	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.010	0.989	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.010	0.989	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.010	0.989	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.011	0.989	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.010	0.989	0.000
M41 Scoliosis	0.011	0.989	0.000
M24.09 Loose body in joint (Site unspecified)	0.010	0.989	0.000
M24.08 Loose body in joint (Other)	0.010	0.989	0.000
M24.06 Loose body in joint-Lower leg	0.010	0.989	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.010	0.989	0.000
M24.04 Loose body in joint (Hand)	0.010	0.989	0.000
M24.03 Loose body in joint (Forearm)	0.010	0.989	0.000
M24.01 Loose body in joint (Shoulder region)	0.010	0.989	0.000
M24.00 Loose body in joint (Multiple sites)	0.010	0.989	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.011	0.989	0.000
S06.5 Traumatic subdural haemorrhage	0.010	0.989	0.000
M80.8 Other osteoporosis with pathological fracture	0.010	0.989	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.010	0.989	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.010	0.989	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.010	0.989	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.010	0.989	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.010	0.989	0.000
M07.3 Other psoriatic arthropathies	0.010	0.989	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.010	0.990	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.010	0.990	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.010	0.990	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.010	0.990	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.010	0.990	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.010	0.990	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.010	0.990	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.010	0.990	0.000
D48.0 Bone and articular cartilage	0.010	0.990	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.010	0.990	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.010	0.990	0.000
M30.2 Juvenile polyarteritis	0.010	0.990	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.010	0.990	0.000
M30.0 Polyarteritis nodosa	0.010	0.990	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.010	0.990	0.000
M32.8 Other forms of systemic lupus erythematosus	0.010	0.990	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.010	0.990	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.010	0.990	0.000
M33.9 Dermatopolymyositis, unspecified	0.010	0.990	0.000
M33.2 Polymyositis	0.010	0.990	0.000
M33.1 Other dermatomyositis	0.010	0.990	0.000
M33.0 Juvenile dermatomyositis	0.010	0.990	0.000
M34.9 Systemic sclerosis, unspecified	0.010	0.990	0.000
M34.8 Other forms of systemic sclerosis	0.010	0.990	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.010	0.990	0.000
M34.1 CR(E)ST syndrome	0.010	0.990	0.000
M34.0 Progressive systemic sclerosis	0.010	0.990	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.010	0.990	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.010	0.990	0.000
M36.3 Arthropathy in other blood disorders	0.010	0.990	0.000
M36.2 Haemophilic arthropathy	0.010	0.990	0.000
M36.1 Arthropathy in neoplastic disease	0.010	0.990	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.010	0.990	0.000
M47 Spondylosis	0.010	0.990	0.000
S01.5 Open wound of lip and oral cavity	0.010	0.990	0.000
M65 Synovitis and tenosynovitis	0.010	0.990	0.000
S06.2 Diffuse brain injury	0.010	0.990	0.000
K62.0 Anal polyp	0.000	0.990	0.010
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.010	0.990	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.010	0.990	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.010	0.990	0.000
M06.38 Rheumatoid nodule (Other)	0.010	0.990	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.010	0.990	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.010	0.990	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.010	0.990	0.000
M06.33 Rheumatoid nodule (Forearm)	0.010	0.990	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.010	0.990	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.010	0.990	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.010	0.990	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.010	0.990	0.000
M17.5 Other secondary gonarthrosis	0.010	0.990	0.000
M85.8 Other specified disorders of bone density and structure	0.010	0.990	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.010	0.990	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.010	0.990	0.000
M25.76 Osteophyte (Lower leg)	0.010	0.990	0.000
D48.1 Connective and other soft tissue	0.010	0.990	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.010	0.990	0.000
S00 Superficial injury of head	0.010	0.990	0.000
M24.29 Disorder of ligament (Site unspecified)	0.010	0.990	0.000
M24.28 Disorder of ligament (Other)	0.010	0.990	0.000
M24.26 Disorder of ligament (Lower leg)	0.010	0.990	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.010	0.990	0.000
M24.24 Disorder of ligament (Hand)	0.010	0.990	0.000
M24.23 Disorder of ligament (Forearm)	0.010	0.990	0.000
M24.22 Disorder of ligament (Upper arm)	0.010	0.990	0.000
M24.21 Disorder of ligament (Shoulder region)	0.010	0.990	0.000
M24.20 Disorder of ligament (Multiple sites)	0.010	0.990	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.010	0.990	0.000
M48 Other spondylopathies	0.010	0.990	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.010	0.990	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.010	0.990	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.010	0.990	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.010	0.990	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.010	0.990	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.010	0.990	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.010	0.990	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.010	0.990	0.000
M15 Polyarthrosis	0.010	0.990	0.000
M25.9 Joint disorder, unspecified	0.010	0.990	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.010	0.990	0.000
M25.3 Other instability of joint	0.010	0.990	0.000
M25.2 Flail joint	0.010	0.990	0.000
M25.1 Fistula of joint	0.010	0.990	0.000
M25.0 Haemarthrosis	0.010	0.990	0.000
M85.9 Disorder of bone density and structure, unspecified	0.010	0.990	0.000
M85.6 Other cyst of bone	0.010	0.990	0.000
M85.5 Aneurysmal bone cyst	0.010	0.990	0.000
M85.4 Solitary bone cyst	0.010	0.990	0.000
M85.3 Osteitis condensans	0.010	0.990	0.000
M85.2 Hyperostosis of skull	0.010	0.990	0.000
M85.1 Skeletal fluorosis	0.010	0.990	0.000
M85.0 Fibrous dysplasia (monostotic)	0.010	0.990	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.010	0.990	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.010	0.990	0.000
M23.07 Cystic meniscus-Capsular lig	0.010	0.990	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.010	0.990	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.010	0.990	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.010	0.990	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.010	0.990	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.010	0.990	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.010	0.990	0.000
M23.00 Cystic meniscus (Multiple sites)	0.010	0.990	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.010	0.990	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.010	0.990	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.010	0.990	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.010	0.990	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.010	0.990	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.010	0.990	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.010	0.990	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.010	0.990	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.010	0.990	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.010	0.990	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.010	0.990	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.010	0.990	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.010	0.990	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.010	0.990	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.010	0.990	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.010	0.990	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.010	0.990	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.010	0.990	0.000
T79-T79 Certain early complications of trauma	0.010	0.990	0.000
M21.0 Valgus deformity, not elsewhere classified	0.010	0.990	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.010	0.990	0.000
D37.4 Colon	0.010	0.990	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.010	0.990	0.000
M82.1 Osteoporosis in endocrine disorders	0.010	0.990	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.010	0.990	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.010	0.990	0.000
M83.9 Adult osteomalacia, unspecified	0.010	0.990	0.000
M83.8 Other adult osteomalacia	0.010	0.990	0.000
M83.5 Other drug-induced osteomalacia in adults	0.010	0.990	0.000
M83.4 Aluminum bone disease	0.010	0.990	0.000
M83.3 Adult osteomalacia due to malnutrition	0.010	0.990	0.000
M83.2 Adult osteomalacia due to malabsorption	0.010	0.990	0.000
M83.1 Senile osteomalacia	0.010	0.990	0.000
M83.0 Puerperal osteomalacia	0.010	0.990	0.000
M49 Spondylopathies in diseases classified elsewhere	0.010	0.990	0.000
M31.9 Necrotising vasculopathy, unspecified	0.010	0.990	0.000
M31.8 Other specified necrotising vasculopathies	0.010	0.990	0.000
M31.7 Microscopic polyangiitis	0.010	0.990	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.010	0.990	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.010	0.990	0.000
M31.3 Wegener's granulomatosis	0.010	0.990	0.000
M31.2 Lethal midline granuloma	0.010	0.990	0.000
M31.1 Thrombotic microangiopathy	0.010	0.990	0.000
M31.0 Hypersensitivity angiitis	0.010	0.990	0.000
M18 Arthrosis of first carpometacarpal joint	0.010	0.990	0.000
M21.9 Acquired deformity of limb, unspecified	0.010	0.990	0.000
M21.8 Other specified acquired deformities of limbs	0.010	0.990	0.000
M21.7 Unequal limb length (acquired)	0.010	0.990	0.000
M21.6 Other acquired deformities of ankle and foot	0.010	0.990	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.010	0.990	0.000
M21.4 Flat foot [pes planus] (acquired)	0.010	0.990	0.000
M21.2 Flexion deformity	0.010	0.990	0.000
M47.9 Spondylosis, unspecified	0.010	0.990	0.000
M07.6 Other enteropathic arthropathies	0.009	0.990	0.000
M07.5 Arthropathy in ulcerative colitis	0.009	0.990	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.009	0.990	0.000
M07.2 Psoriatic spondylitis	0.009	0.990	0.000
M07.1 Arthritis mutilans	0.009	0.990	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.009	0.990	0.000
M43.9 Deforming dorsopathy, unspecified	0.010	0.990	0.000
M43.8 Other specified deforming dorsopathies	0.010	0.990	0.000
M43.6 Torticollis	0.010	0.990	0.000
M43.5 Other recurrent vertebral subluxation	0.010	0.990	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.010	0.990	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.010	0.990	0.000
M43.2 Other fusion of spine	0.010	0.990	0.000
M21.1 Varus deformity, not elsewhere classified	0.010	0.990	0.000
M23.47 Loose body in knee-Capsular lig	0.009	0.990	0.000
M23.46 Loose body in knee-O/unsp lat men	0.009	0.990	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.009	0.990	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.009	0.990	0.000
M23.43 Loose body in knee-Med lig/oth men	0.009	0.990	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.009	0.990	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.009	0.990	0.000
M23.40 Loose body in knee-Mult sites	0.009	0.990	0.000
M84.09 Malunion of fracture (Site unspecified)	0.009	0.990	0.000
M84.08 Malunion of fracture (Other)	0.009	0.990	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.009	0.990	0.000
M84.06 Malunion of fracture (Lower leg)	0.009	0.990	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.009	0.990	0.000
M84.04 Malunion of fracture (Hand)	0.009	0.990	0.000
M84.02 Malunion of fracture (Upper arm)	0.009	0.990	0.000
M84.01 Malunion of fracture (Shoulder region)	0.009	0.990	0.000
M84.00 Malunion of fracture (Multiple sites)	0.009	0.990	0.000
M35.3 Polymyalgia rheumatica	0.010	0.990	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.009	0.990	0.000
M02 Reactive arthropathies	0.009	0.990	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.009	0.990	0.000
M00 Pyogenic arthritis	0.009	0.990	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.009	0.990	0.000
M62 Other disorders of muscle	0.009	0.990	0.000
M61 Calcification and ossification of muscle	0.009	0.990	0.000
M60 Myositis	0.009	0.990	0.000
M94 Other disorders of cartilage	0.009	0.990	0.000
M93 Other osteochondropathies	0.009	0.990	0.000
M92 Other juvenile osteochondrosis	0.009	0.990	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.009	0.990	0.000
T51 Toxic effect of alcohol	0.010	0.990	0.000
M45 Ankylosing spondylitis	0.009	0.990	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.009	0.990	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.009	0.990	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.009	0.990	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.009	0.990	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.009	0.990	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.009	0.990	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.009	0.990	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.009	0.990	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.009	0.990	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.009	0.990	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.009	0.990	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.009	0.990	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.009	0.990	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.009	0.990	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.009	0.990	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.009	0.990	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.009	0.990	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.009	0.990	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.009	0.990	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.009	0.990	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.009	0.990	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.009	0.990	0.000
M24.59 Contracture of joint (Site unspecified)	0.009	0.990	0.000
M24.58 Contracture of joint (Other)	0.009	0.990	0.000
M24.57 Contracture of joint (Ankle and foot)	0.009	0.990	0.000
M24.56 Contracture of joint (Lower leg)	0.009	0.990	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.009	0.990	0.000
M24.54 Contracture of joint (Hand)	0.009	0.990	0.000
M24.53 Contracture of joint (Forearm)	0.009	0.990	0.000
M24.52 Contracture of joint (Upper arm)	0.009	0.990	0.000
M24.51 Contracture of joint (Shoulder region)	0.009	0.990	0.000
M24.50 Contracture of joint (Multiple sites)	0.009	0.990	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.009	0.990	0.000
M24.68 Ankylosis of joint (Other)	0.009	0.990	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.009	0.990	0.000
M24.66 Ankylosis of joint (Lower leg)	0.009	0.990	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.009	0.990	0.000
M24.64 Ankylosis of joint (Hand)	0.009	0.990	0.000
M24.63 Ankylosis of joint (Forearm)	0.009	0.990	0.000
M24.62 Ankylosis of joint (Upper arm)	0.009	0.990	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.009	0.990	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.009	0.990	0.000
M24.79 Protrusio acetabuli-Site unspec	0.009	0.990	0.000
M24.78 Protrusio acetabuli-Other	0.009	0.990	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.009	0.990	0.000
M24.76 Protrusio acetabuli-Lower leg	0.009	0.990	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.009	0.990	0.000
M24.74 Protrusio acetabuli-Hand	0.009	0.990	0.000
M24.73 Protrusio acetabuli-Forearm	0.009	0.990	0.000
M24.72 Protrusio acetabuli-Upper arm	0.009	0.990	0.000
M24.71 Protrusio acetabuli-Shldr region	0.009	0.990	0.000
M24.70 Protrusio acetabuli-Mult sites	0.009	0.990	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.009	0.990	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.009	0.990	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.009	0.990	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.009	0.990	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.009	0.990	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.009	0.990	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.009	0.990	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.009	0.990	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.009	0.990	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.009	0.990	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.009	0.990	0.000
M24.98 Joint derangement, unspecified (Other)	0.009	0.990	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.009	0.990	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.009	0.990	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.009	0.990	0.000
M24.94 Joint derangement, unspecified (Hand)	0.009	0.990	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.009	0.990	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.009	0.990	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.009	0.990	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.009	0.990	0.000
M13.9 Arthritis, unspecified	0.010	0.990	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.009	0.990	0.000
S01.8 Open wound of other parts of head	0.009	0.991	0.000
S02 Fracture of skull and facial bones	0.009	0.991	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations